iosr-JDMS   Volume-22 ~ Issue-6 ~ June 2023

Abstract: Background: COPD , Being An Important Cause Of Mortality And Morbidity In India Have Been Recently Associated With Increased NT-Probnp Levels. NT-Probnp Has Been Used Widely As A Marker Of Heart Failure. However, There Are Few Studies That Analyze The NT-Probnp Levels In COPD Patients. So This Study Was Conducted To Know The Concentrations Of Ntprobnp And The Influence Of The Factors That Usually Modify Them, In A Population Of Patients Of Western Rajasthan With COPD During Episodes Of Decompensation, In Order To Know The Future Uses Of This Biomarker In These Type Of Patients. Materials And Methods: In This Prospective Randomised Observational Study.......

Key Words: COPD, NT-Probnp, GOLD, Biomarker, Pco2

[1]. Daniel, Roy Arokiam1; Aggarwal, Praveen2; Kalaivani, Mani3; Gupta, Sanjeev Kumar1, Prevalence of chronic obstructive pulmonary disease in India: A systematic review and meta-analysis, Lung India: Nov–Dec 2021 - Volume 38 - Issue 6 - p 506-513doi: 10.4103/lungindia.lungindia_159_21
[2]. Fu, S., Ping, P., Wang, F. et al. Synthesis, secretion, function, metabolism and application of natriuretic peptides in heart failure. J Biol Eng 12, 2 (2018). https://doi.org/10.1186/s13036-017-0093-0
[3]. Rogliani P, Ora J, Puxeddu E, Cazzola M. Airflow obstruction: is it asthma or is it COPD? Int J Chron Obstruct Pulmon Dis. 2016 Nov 30;11:3007-3013. doi: 10.2147/COPD.S54927. PMID: 27942210; PMCID: PMC5137932.
[4]. Janssen R, Piscaer I, Franssen FME, Wouters EFM. Emphysema: looking beyond alpha-1 antitrypsin deficiency. Expert Rev Respir Med. 2019 Apr;13(4):381-397. doi: 10.1080/17476348.2019.1580575. Epub 2019 Feb 22. PMID: 30761929.
[5]. Halbert RJ, Natoli JL, Gano A, Badamgarav E, Buist AS, Mannino DM. Global burden of COPD: systematic review and meta-analysis. The European respiratory journal. 2006;28(3):523-32.

Abstract: Background: ACS Encompasses A Wide Range Of Clinical Manifestations From STEMI To NSTEMI Or UA. It Is More Frequent In India, Which Has A Greater Rate Than The Rest Of The World. STEMI Individuals Were More Likely To Be Identified Than NSTEMI Or UA. The Most Common Cause Underlying ACS Is Atherosclerosis. Hypertension, Diabetes, Dyslipidemia And Social Habits Are All Major Risk Factors. In Majority Of Individuals Suffering From NSTEMI Have A Higher Annual Death Rate Than Those Experiencing STEMI. The Study's Major Goal Is To Find Out Which Risk Variables Lead To ACS In An Observational Study. To Identify The Therapeutic Plan For Patients Based On Clinical Profile, To Assess The Co Morbidities As Well As The Therapeutic Approach And The Parameters On Which ACS Has Indeed Been Confirmed..........

Keywords: Acute Coronary Syndrome, Dual Antiplatelet Therapy, Atherosclerosis, Hypertension

[1]. Amsterdam EA, Wenger NK, Brindis RG, et al. 2014 AHA/ACC guideline for the management of patients with non-ST elevation acute coronary syndromes: a report of the American College of Cardiology/ American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014; 64(24): e139-228.
[2]. Xavier D, Pais P Devereaux PJ, et al. Treatment and outcomes of acute coronary syndromes in India (CREATE): a prospective analysis of registry data Lancet. Apr 26, 200; 371(9622): 1435-1442.
[3]. Bastante T, Rivero F Cuesta J, Benedicto A, Restrepo J, Alfonso F. Non-atherosclerotic causes of acute coronary syndrome: recognition and management. Curr Cardiol Rep. 2014; 16(11): 543.
[4]. Varghese T, et al. non-ST elevation acute coronary syndrome in women and the elderly: Recent updates and stones still left unturned. F 1000 Research. 2020; doi: 10.12688/f1000 research. 16492.1.
[5]. Montecucco F et al; Pathophysiology of ST-segment elevation myocardial infarction; Novel mechanisms and treatment. Eur Heart J 37: 1268, 2016.

Abstract: Background: Prolapsed Inter Vertebral Disc (PIVD)Is Commonly Encounter Clinical Entity Which 5-20 Cases Per 1000 Adults Annually And Is Most Common In People In 3rd To 5th Decade Of Life. Pregabalin And Duloxetine Are The Commonly Prescribed Medicine For Controlling Neuropathic Pain In Many Circumstances. But There Is A Limited Number Of Studies Comparing The Efficacy And Safety Of Pregabalin And Duloxetine. Materials & Methods: An Comparative Study Conducted In The Department Of PMR At AGMC And GBP Hospital Between July, 2021 To April, 2022 Among Those Patients Attending The OPD Among 100 Participants Each Treatment Group Of Pregabalin And Duloxetine In PIVD With Neuropathic Pain Due To PIVD. The Efficacy Was Assessed By VAS, DN4 And LANSS Assessment. Both Descriptive And Inferential Statistics Were Used To Analyze The Data.......

Keywords : PIVD, Neuropathic Pain, Pregabalin, Duloxetine, Efficacy, Adverse Effects

[1]. The International Association for the Study of Pain (IASP) revised the definition of Pain available at:
https://www.britishpainsociety.org/about/what-is-pain/. Assessed on 23 Nov, 2022.
[2]. Prolapse Intervertebral Disc. Available at: https://www.medindia.net/ patients/patientinfo/ prolapse-of-intervertebral-disc.htm. Assessed on 23 Nov, 2022.
[3]. Prolapse Intervertebral Disc. Available at: https://orthopedicclinic.com.sg/prolapsed-intervertebral-disc. Assessed on 23 Nov, 2022.
[4]. Fjeld OR, Grovle L, Heeland j, Smastuen MC, Solberg TK Zwart JA, Grotle M. Complications, reoperations, readmissions and lenth of Hospital stay in 34639 surgical cases of lumbar disc herniation. Bone Joint J.2019;101-B(4):470-77.
[5]. Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology. 2008;70(18):1630-35.

Abstract: Background: Laproscopic Cholecystectomy Using Four Port Is Standard Operative Procedure To Remove Gall Bladder Due To Cholelitihiasis With Cholecystitis But New Method As Three Port Is Being Tried To Get Advantage In Reducing Post Op Pain,Duration Of Surgery,Conversion Rate,Complications,Cost,Cosmesis And Hospital Stay.The Main Objective Of This Study Is To Evaluate Efficacy Of Laproscopic Cholecystectomy By Three Port Over Standard Four Port Technique. Material & Methods: In This Prospective Observational Study,100 Patients Undergoing Laproscopic Cholecystectomy Due To Chronic Cholecystitis With Cholelithiasis Dicivded By A Randomized Blind Trail Equally Into Two Groups.....

Keywords: Cholecystitis, Cholelithiasis, Three Port Lap Cholecystectomy, Four Port Lap Cholecystectomy

[1]. Barbara L, Sama C, Labate AM, Taroni F, Rusticali AG, Festi D, Sapio C, Roda E, Banterle C, Puci A, Formentini F. A population study on the prevalence of gallstone disease: the Sirmione Study. Hepatology. 1987 Sep 1;7(5):913-7.Cuschieri A. Laparoscopic cholecystectomy. J R CollSurgEdinb 1999; 44:187-92.
[2]. Ji W, Li LT, Li JS. Role of laparoscopic subtotal cholecystectomy in the treatment of complicated cholecystitis. Hepatobiliary Pancreat Dis Int. 2006 Nov 15;5(4):584-9. [PubMed]
[3]. Navez B, Mutter D, Russier Y, et al. Safety of laparoscopic approach for acute cholecystitis: retrospective study of 609 cases. World J Surg. 2001; 25:1352–6. [PubMed]
[4]. Schafer M, Krahenbuhl L, Buchler MW. Predictive factors for the type of surgery in acute cholecystitis. Am J Surg. 2001; 182: 291 –7. [PubMed]
[5]. Kauvar DS, Braswell A, Brown BD, Harnisch M. Influence of resident and attending surgeon seniority on operative performance in laparoscopic cholecystectomy. J Surg Res. 2006; 132:159-63. Rai R, Sinha A, Rai S: Randomised clinical trial of open versus laparoscopic cholecystectomy in the treatment of acute cholecystitis. Br J Surg. 2005, 92:44-49. Br J Surg. 2005; 92:494-9.

Abstract: Background: Various Literatures Were Available In Different Part Of World And India Regarding Holistic Study Of Lung Pattern And Their Branches And Its Clinical Importance However, There Is Limited Data In This Part Of India. Materials And Methods: 38 Pairs Of Adults And 11 Pairs Of Fetus Lungs Are Examined By Conventional Dissection Method At Dissection Hall, AGMC, Agartala, Tripura. The Branching Pattern Of Lobar Bronchi Was Identified, Named And Observed Its Variation And Compared With The Previous Data Of Various Author's. Data Were Collected In Performa And Descriptive Statistics Were Used To Analyze The Data........

Keywords: Human Cadaver, Lung, Lobar Bronchi, Branching Pattern

[1]. Shah P, Johnson D, Standring S. Thorax. In: Standring S, editor. Gray's Anatomy: The Anatomical Basis of Clinical Practice. 39th ed. Edinburgh: Churchill Livingstone; 2005, 1068-9.
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Abstract:Background: This Clinical Work Was Conducted On Two Cases To Evaluate The Healing Of Bony Periapical Lesions After Surgical Endodontics. Materials And Methods: Conventional Endodontic Treatment Followed By Surgical Endodontic Treatment Was Performed By Confirming Anatomical Configuration Of Bony Defects Like Dehiscence, Before And After Treatment Procedure With A Cone Beam Computed Tomography (CBCT) Image Analysis. Results: It Was Observed That There Was Gradual Increase In Bone Density And Reduction In Surface Area Of Radiolucent Area Over 6 Month Follow-Up In Both The Cases. Conclusion: Sticky Bone In Combination Along With Resorbable GTR Membrane And PRF Membrane Was Seen To Be Promising In Inducing And Accelerating Hard And Soft Tissue Regeneration.

Keywords: Dehiscence, CBCT, Apicoectomy, Guided Tissue Regeneration (GTR), Regeneration, Platelet-Rich Fibrin, Surgical Endodontics.

[1]. Lin L, Chen MY, Ricucci D, Rosenberg PA. Guided tissue regeneration in periapical surgery. J Endod 2010; 36:618-25.
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[3]. BashutskiJD,WangHL.Periodontal and endodontic regeneration. JEndod 2009Mar;35:321-
8.Doi:10.1016/j.joen.2008.11.023.PMID:19249588.
[4]. Dahlin C, Linde A, Gottlow J, Nyman S. Healing of bone defects by guided tissue regeneration. Plast Reconstr Surg 1988;81:672–6.
[5]. Saluja H, Dehane V, Mahindra U. Platelet-rich fibrin: Asecond generation platelet concentrate and a new friend of oral and maxillofacial surgeons. Ann Maxillofac Surg 2011;1:53-7.

Abstract: Since The 1970s, Modern Implantology Is Based On A Concept Of Surgery With Flap Elevation. Gradually, Several Clinical Trials Demonstrated That A Mid-Crestal Incision Gives Similar Success Rates Compared To Those Obtained Using The Classical Protocol 1. However, Over The Past Decade In Medicine It Has Been Established The Concept Of Minimally Invasive Surgery, Consisting In Taking Advantage Of Advancements Experienced In Diagnostic Techniques And Specific Surgical Instruments, To Perform Surgical Procedures Infringing As Less Damage As Possible To The Patient Through Minimal Incisions (Envelope Incision In The Beginning, Actually Without Lineal Incision (Punch), Reducing The Size Of The Instruments8.

Keywords: Dental Implants, Flapless Surgery, Advantage, Limitations, Literature Review

[1]. Kim J-I, Choi B-H, Li J, Xuan F, Jeong S-M. Blood vessels of the peri-implant mucosa: a comparison between flap and flapless procedures. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009;107:508- 12
[2]. Belser UC, Schmid B, Higginbottom F, Buser D. Outcome analysis of implant restorations located in the anterior maxilla: a review of the recent literature. Int J Oral Maxillofac Implants. 2004;19:30-42.
[3]. Campelo LD, Camara JRD. Flapless implant surgery: a 10-year clinical retrospective analysis. Int J Oral Maxillofac Implants 17:271-6.
[4]. Jeong S-M, Choi B-H, Li J, Kim H-S, Ko C-Y, Jung J-H, et al. Flapless implant surgery: an experimental study. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007;104:24-8.
[5]. Casap N, Tarazi E, Wexler A, Sonnenfeld U, Lustmann J. Intraoperative computerized navigation for flapless implant surgery and immediate loading in the edentulous mandible. International Journal of Oral & Maxillofacial Implants. 2005 Jan 1;20(1).

Abstract: Background: In Dental Practice, Dentine Hypersensitivity (DHS) Is A Prevalent Clinical Concern Characterized By Short, Sharp Pain Arising From Exposed Dentin In Response To Non-Noxious Stimuli. A Desensitizing Agent Used To Alleviate DHS Can Also Influence The Bacterial Biofilm. Our Study Compares The Impact Of CSPS And Fluoride-Containing Desensitizing Toothpastes On The Formation Of Streptococcus Mutans Biofilm Based On The Assumption That Any Changes To The Tooth Surface May Have An Effect On Subsequent Biofilm Formation. The Present Study Might Be The First To Compare The Effects Of CSPS And Fluoride Containing Dentifrices On Biofilm Formation......

Keywords: Streptococcus Mutans, Bacterial Biofilm, Calcium Sodium Phosphosilicate Toothpaste, Fluoride Toothpaste, Dentin Hypersensitivity.

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