iosr-JDMS   Volume-23 ~ Issue-9 ~ September 2024

Abstract: Rehabilitating patients with a toothless upper jaw (edentulous maxilla) opposed by natural lower front teeth poses significant challenges for clinicians. This condition, known as Combination Syndrome (Kelly, 1972), is characterized by......

[1] Glossary Of Prosthodontic Terms Terms (2005) J Prosthet Dent 94: 10-92.
[2] Kelly E (1972) Changes Caused By A Mandibular Removable Partial Denture Opposing A Maxillary Complete Denture. J Prosthet Dent 27: 140-150.
[3] Shen K, Gongloff Rk. Prevalence Of The 'Combination Syndrome 'Among Denture Patients. J Prosthet Dent 1989; 62: 642-4.
[4] Jameson Ws. The Use Of Linear Occlusion To Treat A Patient With Combination Syndrome: A Clinical Report. J Prosthet Dent 2001; 85: 15-9
[5] López-Roldán A, Abad Ds, Ber Tomeu Ig, Castillo Eg, Otaolaurruch Es. Bone Resorption Processes In Patients Wearing Overdentures. A 6-Years Retrospective Study. Med Oral Patol Oral Cir Bucal 2009; 14: 203-9.

Abstract: Periapical lesions develop as a sequela to pulpal diseases. The majority of inflammatory periapical lesions are initially treated with conservative non-surgical procedures. The success of root canal treatment is based on thorough cleaning, shaping and obturation of the root canal system. Calcium hydroxide and triple antibiotic paste (TAP) are recommended as intracanal medicaments due to its antibacterial properties. This case report describes the non-surgical management of a large cyst-like periapical lesion in relation to the maxillary lateral incisor of a 19-year-old male with the chief complaint of periodic swelling and pus drainage from the palatine region with a history of a traumatic accident in the same area. The present case highlights the use of calcium hydroxide and TAP as an interappointment endodontic dressing for non-surgical management of large periapical radiolucency, which resulted in favourable clinical and radiographic outcomes.

Keywords: Non-surgical Healing, TAP, Metapex, Periapical Lesion

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[3] Kumar Nk, Brigit B, Annapoorna Bs, Naik Sb, Merwade S, Rashmi K. Effect Of Triple Antibiotic Paste And Calcium Hydroxide On The Rate Of Healing Of Periapical Lesions: A Systematic Review. J Conserv Dent Jcd. 2021;24(4):307–13.
[4] Haapasalo M, Udnæs T, Endal U. Persistent, Recurrent, And Acquired Infection Of The Root Canal System Post‐Treatment. Endod Top. 2003 Nov;6(1):29–56.
[5] Bhaskar Sn. Nonsurgical Resolution Of Radicular Cysts. Oral Surg Oral Med Oral Pathol. 1972 Sep;34(3):458–68.

Abstract: Implant-supported prosthesis has emerged as preferred treatment of choice due to the irreliable functional and aesthetic outcomes. However, the clinician can encounter several challenges in accomplishing the task. Failure to understand stress factors and stress distribution often lead to bone loss and restoration failure. This case study aims to provide a comprehensive explanation of the entire prosthetic rehabilitation process using a fixed dental prosthesis supported by a tooth and an implant, all in accordance with standard guidelines.

Keywords: dental implant, fixed dental rehabilitation, FP-3 prosthesis, DMLS

[1] Maló P, De Sousa St, De Araújonobre M, Mouraguedes C, Almeida R Et Al. A Individual Lithium Disilicate Crowns In A Full-Arch, Implant-Supported Rehabilitation: A Clinical Report. J Prosthodont 2014 Aug; 23(6):495500.
[2] Prabhu R, Prabhu G, Baskaran E, Arumugam Em. Clinical Acceptability Of Metal-Ceramic Fixed Partial Dental Prosthesis Fabricated With Direct Metal Laser Sintering Technique- 5 Year Follow-Up. J Indian Prosthodont Soc. 2016 Apr-Jun; 16(2):193-7.
[3] Krennmair S, Weinländer M, Malek M, Forstner T, Krennmair G, Stimmelmayr M. Mandibular Full-Arch Fixed Prostheses Supported On 4 Implants With Either Axial Or Tilted Distal Implants: A 3-Year Prospective Study. Clin Implant Dent Relat Res. 2016 Dec; 18(6):1119-1133.3
[4] Oscar Figueras-Alvarez, Oriol Canto-Naves, Francisco Real-Voltas, Miguel Roiget Al. Protocol For The Clinical Assessment Of Passive Fit For Multiple Implant-Supported Prostheses: A Dental Technique Doi:10.1016/J.Prosdent.2020.10.001 [5] Brizuela-Velasco A, Álvarez-Arenal Á, Ellakuria-Echevarria J, Del Río-Highsmith J, Santamaría-Arrieta G, Martín-Blanco N. Influence Of Articulating Paper Thickness On Occlusal Contacts Registration: A Preliminary Report. Int J Prosthodont. 2015 Jul-Aug;28(4):360-2. Doi: 10.11607/Ijp.4112. Pmid: 26218017.

Abstract: Background: substantial progress has been made in terms of the immediate placement of dental implants after tooth extraction. In cases were the bone is healthy with no atrophy, Periapical lesions, infection and enough bone component is available immediate implant is considered. Recently implant abutment welding was introduced specially for those edentulous patients who need immediate loading and who wanted to go out of the surgery with full load of teeth.....

Keywords: Computer guided, STL model, wire bending, implant welding, stability, osseointegration, time consumption

[1] The Glossary Of Prosthodontic Terms. J Prosthet Dent 2017;117(5s):E1–105.
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[3] Felton Da. Edentulism And Comorbid Factors. J Prosthodont 2009;18(2):88–96.
[4] Dye B, Thornton-Evans G, Li X, Et Al. Dental Caries And Tooth Loss In Adults In The United States, 2011-2012. Nchs Data Brief 2015;(197):197.
[5] Felton Da. Complete Edentulism And Comorbid Diseases: An Update.J Prosthodont 2016;25(1):5–20.

Abstract: Background: Birth asphyxia and its attendant complications remain a common problem in our neonatal intensive care units. Compelling evidence from various epidemiologic studies shows that Acute Kidney Injury (AKI) is indeed one of the commonest complications of birth asphyxia. The kidneys are sensitive to oxygen deprivation and renal insult may occur within few hours of hypoxic-ischemic episode, which if prolonged could lead to irreversible cortical and or tubular necrosis. Aim: To determine the prevalence.....

[1] American College Of Obstetrics And Gynecology, Task Force On Neonatal Encephalopathy; American Academy Of Paediatrics. Neonatal Encephalopathy And Neurologic Outcome, 2nd Edition. Washington Dc: American College Of Obstetricians And Gynecologists; 2014.
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Abstract: Background: Managing postoperative pain in pediatric anesthesia is challenging, with caudal epidural anesthesia being a preferred technique for its safety and efficacy. Enhancing analgesia duration through adjuvants like midazolam may improve outcomes. Objective: This study compares the effectiveness of caudal epidural bupivacaine alone versus a bupivacaine-midazolam mixture in children undergoing repair of congenital inguinal hernia, circumcision, and hypospadias repair, focusing on postoperative analgesia duration and side effects.....

Keywords: Postoperative analgesia, Caudal epidural anesthesia, Congenital inguinal hernia

[1] Marjanovic V, Budic I, Stevic M, Simic D. A Comparison Of Three Different Volumes Of Levobupivacaine For Caudal Block In Children Undergoing Orchidopexy And Inguinal Hernia Repair. Med Princ Pract2017;26:331–336
[2] Najman Ie, Frederico Tn, Segurado Avr, Tsa, Kimachi Pp, Tsa. Caudal Epidural Anesthesia: An Anesthetic Technique Exclusive For Pediatric Use? Is It Possible To Use It In Adults? What Is The Role Of The Ultrasound In This Context? Rev Bras Anestesiol 2011;61(1): 95-109.
[3] Jaitawat Ss, Kushwaha R, Nagina, Gupta S. Comparision Of Caudal Bupivacaine With Additives Fantanyl Or Ketamine For Post-Operative Pain Relief In Children: A Randomized Controlled, Double Blinded Study, Indian Journal Of Clinical Anaesthesia, 2015;2(4):246-250
[4] Mogahed Mm, Salama Er. Efficacy Of Caudal Ketamine With Different Concentrations Of Levobupivacaine For Postoperative Analgesia In Paediatricsubumblical Surgeries. J Anesth Clin Res 2017; 8: 758

Abstract: A 39-year-old man had been diagnosed after rolling out all the other possible causes as having intracranial hypertension with bilateral papilledema secondary to Behçet's disease with normal MRI scan. Despite treatment with steroids, methylprednisolone and repetitive LPs, he had little to no improvement. The patient later underwent a ventriculoperitoneal shunt operation with corticosteroid therapy and adjuvant treatment with topiramate and acetazolamide, which resulted in symptoms improvement. Thus, it is important to consider NBD in the differential diagnosis of patients with intracranial hypertension and bilateral papilledema and also ventriculoperitoneal shunting as an effective therapeutic alternative when medical treatment fail to normalize the intracranial hypertension building up..

Keywords: Behçet's disease, neurological involvement, intracranial pressure, CSF, ventriculoperitoneal shunt

[1] Thierry Chabin. La Maladie De Behcet : A Propos D'un Cas De Neuro-Behcet D'aspect Pseudo-Tumoral. Médecine Humaine Et Pathologie. 1989.
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[5] Ascaso F.J, Rodriguez A, Cristóbal J.A. Documenta Ophthalmologica. 2002;105(3), 291–299.

Abstract: Behavioral and psychological symptoms of dementia (BPSD), which include agitation, aggression, anxiety, and psychosis, are a common consequence of dementia[1]. BPSD is nearly universal in patients with dementia, where it is correlated with the advanced stage of the illness[2]. Agitation is among the most distressing symptom of dementia, which not only affects patients but also clinicians and caregivers. BPSD is of clinical significance as it is often strongly associated with functional impairment. Therefore, in addition to treating cognitive impairments, targeting BPSD should be considered a priority by mental health providers[3]. Nonpharmacological interventions should be the first line when treating BPSD although many barriers exist in clinical settings to implement......

[1] Cerejeira J, Lagarto L, Mukaetova-Ladinska Eb: Behavioral And Psychological Symptoms Of Dementia. Front Neurol 2012; 3:73
[2] Steinberg M, Shao H, Zandi P, Et Al: Point And 5-Year Period Prevalence Of Neuropsychiatric Symptoms In Dementia: The Cache County Study. Int J Geriatr Psychiatry 2008; 23:170–177
[3] Katona C, Livingston G, Cooper C, Et Al: International Psychogeriatric Association Consensus Statement On Defining And Measuring Treatment Benefits In Dementia. Int Psychogeriatr 2007; 19:345–354
[4] Mcclam Td, Marano Cm, Rosenberg Pb, Et Al: Interventions For Neuropsychiatric Symptoms In Neurocognitive Impairment Due To Alzheimer's Disease: A Review Of The Literature. Harv Rev Psychiatry 2015; 23:377–393.

Abstract: Characterised by a myriad of etiologies, acute pancreatitis occurring in the setting of hypercalcemia is rare. It is crucial to recognise the wide range of symptoms and signs of hypercalcemia in this regard. After having managed the patient according to standard protocols for pancreatitis and specific measures directed at reducing serum calcium levels, it is imperative to warrant an aggressive search for the etiology of hypercalcemia. This is pivotal in ultimately deciding management strategies and guiding further definite treatment plans. Here, we present a unique case of hypercalcemia, which on amalgamating clinical, biochemical, radiological and pathological clues, ultimately unraveled a rather enigmatic presentation of a common disease entity.

Keywords: hypercalcemia, acute pancreatitis, tuberculosis, granulomatous diseases, hyperparathyroidism

[1] Negrón Alick Fm, Aranda G De Q, Ruiz F, Garcia Bejarano He, Marrero Santiago Ei, Pagan Maldonado D, Rivera Benitez Cx, Mora Castillo V, Ahmad Kad, Robledo Amezcua M, Franco Martinez Am, Duran Gonzalez E, Rodriguez Lara Sq, Castañeda Moreno Ja, Alvarez Palazuelos Le, Davalos Benitez Ma. Wcn24-371 Tuberculosis-Induced Hypercalcemia In Previous Stage 5 Ckd Hypocalcemia: A Complex Diagnostic Dilemma. Kidney Int Rep. 2024;9(4 Suppl):S1-S3. Doi:10.1016/J.Ekir.2024.01.001.
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[4] Gkonos Pj, London R, Hendler Ed. Hypercalcemia And Elevated 1,25-Dihydroxyvitamin D Levels In A Patient With End-Stage Renal Disease And Active Tuberculosis. N Engl J Med.
[5] Shai F, Baker Rk, Addrizzo Jr, Wallach S. Hypercalcemia In Mycobacterial Infection. J Clin Endocrinol Metab. 1972;34:251–6..

Abstract: Febrile seizures are the seizures that occur between the ages of 6 months to 60 months with a fever spike of 38 degree Celsius or higher that are not the result of CNS infections or any metabolic imbalance and that occur in the absence of history of prior afebrile seizures. A simple febrile seizure is a primary generalized tonic clonic attack associated with fever lasting for less than 5 minutes and not recurrent within a 24 hour period Recurrence of febrile seizure is common and causes for recurrence includes age less than 1 year, unrecognized high fever spikes, incompliance of clobazam. Educating and counseling of parents about the condition is important....

[1] Abdelrahman Ra, Shokeir Ma, Abd Elmagid Ds. (2020): Serum Zinc Level In Children Presenting With Febrile Seizures. Alexandria Journal Of Pediatrics. 2020 Sep 1; 33(3):144.
[2] Arul J, Kommu Pp, Kasinathan A, Ray L, Krishnan L. (2020): Zinc Status And Febrile Seizures: Results From A Cross-Sectional Study. Journal Of Neurosciences In Rural Practice
[3] Debroy P, Baruah A.: Serum Zinc And Magnesium Levels In Children With Febrile Seizure: A Hospital Based Cross-Sectional Study. Ctice. 2020 Oct; 11(04):597-600.
[4] Ganesh R, Janakiraman L. (2008): Serum Zinc Levels In Children With Simple Febrile Seizure. Clinical Pediatrics. 2008 Mar; 47(2):164-6.
[5] Hameed Za, El-Tellawy Mm, Embaby M, Kamel Ys. (2019): Relation Of Iron And Zinc Deficiencies To The Occurrence Of Febrile Convulsions. Journal Of Pediatric Neurosciences. 2019 Apr; 14(2):61 11.

Abstract: Oral cavity harbours millions of bacteria which interact to form biofilm and thereby helps to maintain homeostasis. Dysbiosis in the normal flora leads to various oral diseases such as dental caries and periodontitis. Dental caries is the most common oral disease where acids are produced by fermentation of carbohydrate molecules by various bacteria such as Streptococcus mutans, Lactobacillus sp, leading to demineralization of the tooth structure. Another disease of interest is Periodontitis where subgingival plaque is associated with the progression of gingivitis to periodontitis. After the success of Fecal Microbial transplant, researchers has been inspired to find out whether Oral Microbial transplant can be used in the treatment of oral diseases..

[1] Preethi Balan, Georgios Belibasakis, Saso Ivanovski, Nagihan Bostanci & Chaminda Jayampath Seneviratne. (2023) Community Dynamics Of Subgingival Microbiome In Periodontitis And Targets For Microbiome Modulation Therapy. Critical Reviews In Microbiology 49:6, Pages 726-738.
[2] Nath S, Zilm P, Jamieson L, Kapellas K, Goswami N, Ketagoda K, Weyrich Ls. Development And Characterization Of An Oral Microbiome Transplant Among Australians For The Treatment Of Dental Caries And Periodontal Disease: A Study Protocol. Plos One. 2021 Nov 29;16(11):E0260433. Doi: 10.1371/Journal.Pone.0260433. Pmid: 34843568; Pmcid: Pmc8629173.
[3] Jinzhi He, Xin Shen, Di Fu, Yutao Yang, Kaixin Xiong, Lei Zhao, Huixu Xie, Georege Pelekos & Yan Li. (2022) Human Periodontitis-Associated Salivary Microbiome Affects The Immune Response Of Diabetic Mice. Journal Of Oral Microbiology 14:1.
[4] Nascimento, M. (2017). Oral Microbiota Transplant: A Potential New Therapy For Oral Diseases. Journal Of The California Dental Association, 45(10), 565–568. Https://Doi.Org/10.1080/19424396.2017.12222506

Abstract: Background And Rationale Soft denture liners in prosthetic dentistry are crucial for patient comfort and oral health preservation, but concerns about disinfectants' properties, viscoelasticity, surface hardness, and color stability have been raised.disinfection treatments, such as 5.25% sodium hypochlorite and 5% chlorhexidine, are commonly used to disinfect soft liners, but the impact on their physical properties is limited....

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Abstract: Background and objectives: recurrent respiratory infections are currently a public health problem due to their high costs and resistance to treatments as well increase morbidity and mortality. An imbalance in the homeostasis of progressive cellular and humoral immunity the application of immunotherapy with trained immunity vaccines (ivie) is currently a therapeutic option in all patients with recurrent respiratory infections by training innate and adaptive immunity by reducing episodes of respiratory exacerbations and improving the quality of life of patients. Methods: using.........

[1] Agenais A, Villalba-Guerrero C And Olivier M (2023) Trained Immunity: A "New" Weapon In The fight Against Infectious Diseases. Front. Immunol. 14:1147476. Doi: 10.3389/Fimmu.2023.1147476
[2] Ochando, J., Mulder, W.J.M., Madsen, J.C. Et Al. Trained Immunity — Basic Concepts And Contributions To Immunopathology. Nat Rev Nephrol 19, 23–37 (2023). Https://Doi.Org/10.1038/S41581-022-00633-5
[3] Pérez-Sancristóbal I, De La Fuente E, Álvarez-Hernández MP, Guevara-Hoyer K, Morado C, Martínez-Prada C, Freites-Nuñez D, Villaverde V, Fernández-Arquero M, Fernández-Gutiérrez B, Sánchez-Ramón S, Candelas G. Long-Term Benefit Of Perlingual Polybacterial Vaccines In Patients With Systemic Autoimmune Diseases And Active Immunosuppression. Biomedicines. 2023 Apr 13;11(4):1168. Doi: 10.3390/Biomedicines11041168. PMID: 37189785; PMCID: PMC10136188.
[4] Brandi P, Conejero L, Cueto FJ, Martínez-Cano S, Dunphy G, Gómez MJ, Relaño C, Saz-Leal P, Enamorado M, Quintas A, Dopazo A, Amores-Iniesta J, Del Fresno C, Nistal-Villán E, Ardavín C, Nieto A, Casanovas M, Subiza JL, Sancho D. Trained Immunity Induction By The Inactivated Mucosal Vaccine MV130 Protects Against Experimental Viral Respiratory Infections. Cell Rep. 2022 Jan 4;38(1):110184. Doi: 10.1016/J.Celrep.2021.110184. PMID: 34986349; PMCID: PMC8755442.
[5] Subiza JL, Palomares O, Quinti I And Sanchez-Ramon S (2021). Editorial: Trained Immunity-Based Vaccines. Front. Immunol. 12:716296.Doi: 10.3389/Fimmu.2021.716296.

Abstract: Résumé Introduction : La Polyarthrite Rhumatoïde (PR) est une maladie inflammatoire auto-immune chronique. Son diagnostic repose sur un ensemble de critères cliniques, radiologiques et biologiques. En effet les anti-peptides cycliques citrullinés (anti-CCP) constituent des marqueurs spécifiques de la PR. L'objectif de notre étude est de déterminer la prévalence des anti-CCP chez les patients présentant une suspicion de PR......

[1] Van Steenbergen Hw, Aletaha D, Beaart-Van De Voorde Ljj, Et Al. Eular Defi-Nition Of Arthralgia Suspicious For Progression To Rheumatoid Arthritis. Annrheum Dis 2017 ;76 :491–6.
[2] Hua C, Daien Ci, Combe B, Et Al. Diagnosis, Prognosis And Classification Of Earlyarthritis: Results Of A Systematic Review Informing The 2016 Update Of Theeular Recommendations For The Management Of Early Arthritis. Rmd Open2017 ;3: E000406.
[3] Combe B, Landewe R, Daien Ci, Et Al. 2016 Update Of The Eular Recommenda-Tions For The Management Of Early Arthritis. Ann Rheum Dis 2017 ;76 :948–59.
[4] Zhu, J. N., Nie, L. Y., Lu, X. Y., & Wu, H. X. (2019). Meta-Analysis: Compared With Anti-Ccp And Rheumatoid Factor, Could Anti-Mcv Be The Next Biomarker In The Rheumatoid Arthritis Classification Criteria. Clinical Chemistry And Laboratory Medicine (Cclm), 57(11), 1668-1679.
[5] Khan, T., Jose, R. J., Renzoni, E. A., & Mouyis, M. (2021). A Closer Look At The Role Of Anti-Ccp Antibodies In The Pathogenesis Of Rheumatoid Arthritis-Associated Interstitial Lung Disease And Bronchiectasis. Rheumatology And Therapy, 8(4), 1463-1475