Abstract: Anemia is a condition with a reduced amount of total blood cell (RBC) or blood hemoglobin or reduced blood oxygen-carrying capacity. Blood loss, decreased production of red blood cells and increased breakdown of red blood cells can cause anemia. Trauma and gastrointestinal bleeding are a source of blood loss, but certain factors, including iron deficiency, vitamin B12 deficiency, lower erythropoietin level, slight bone marrow neoplasm thalassemia, genetic disorders such as sickle cell, parasitic infection including malariaand other autoimmune diseases are the causes of lower erythrocytes. Anemia is also associated with oxidative stress owing to two processes. Oxidative stress affects the function of the kidney......
Key words: Anemia, Oxidative Stress, Red blood cell, Erythropoiesis, Hemoglobin
[1]. Aapro, M. S., &Linkb, H. (2008). Anemia Management with Erythropoiesis-Stimulating Agents. The Oncologist, 13, 33-36. [2]. Amer, J., Atlas, D., &Fibach, E. (2008). N-acetylcysteine amide (AD4) attenuates oxidative stress in beta-thalassemia blood cells. Biochimica et Biophysica Acta (BBA)-General Subjects, 1780(2), 249-255. [3]. Beutler, E., &Waalen, J. (2006). The definition of anemia: what is the lower limit of normal of the blood hemoglobin concentration? Blood, 107(5), 1747-1750. [4]. Birben, E., Sahiner, U. M., Sackesen, C., Erzurum, S., &Kalayci, O. (2012). Oxidative stress and antioxidant defense. World Allergy Organization Journal, 5(1), 9-19. [5]. Bissinger, R., Bhuyan, A. A. M., Qadri, S. M., & Lang, F. (2019). Oxidative stress, eryptosis and anemia: a pivotal mechanistic nexus in systemic diseases. The FEBS journal, 286(5), 826-854.