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| Paper Type | : | Research Paper |
| Title | : | Histological changes caused by using Celebrex on the stomach, small intestine, and liver of mouse |
| Country | : | Saudi Arabia |
| Authors | : | biauhS riahuZ niaguL || heiteitS layriF |
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: | 10.9790/3008-1301010107  |
Abstract: The administrations of non- steroidal anti-inflammatory drugs (NSAIDs) are widely used due to their les adverse effects and good safety. Celebrex is one of NSAID which works by reducing enzymes that cause inflammation and pain in the body. Celebrex is used as an antipyretics, analgesics, and in the treatment of muscles aches. It also used for patient with rheumatoid arthritis to reduce pain as an anti- inflammatory agent for a long time. However, some recent studies have reported that rheumatoid patients have been identified for varying degrees of stomach, small intestinal bleeding, and liver injuries. This histological investigation helps to explain the adverse effect of Celebrex on the previously mentioned organs. The animals were divided to three groups, group A control, group B treated for four...........
Keywords: Celebrex, NSAIDs, side effects, Histological changes
[1]. .Histology at SIU SOM (2010) "Liver". From: http://www.siumed.edu/ dking2/erg/liver.htm
[2]. .VIVO Pathophysiology, Digestive System "Hepatic Histology". From: http://www.vivo.colostate.edu/hbooks/pathphys/digestion/liver/histo_lobule.html
[3]. Ajuebor MN, Singh A and Wallace JL(2000). Cyclooxygenase-2-derived prostaglandin D2 is an early anti- inflammatory signal in experimental colitis. Gastointestinal and liver Physiology, 279;238-244.
[4]. Arellanes-Robledo J, Marquez-Rosado L, Perez-Carreon JL, Fattel-Fazenda S, Aguirre-Garacia J and Villa-Trevino S (2006).. Celecoxib induces regression of putative preneoplastic lesions in rat liver. Anticancer Research Journal, 26; 1271-1280
[5]. Bednarek D, Ciesielska AS, ZdzisinAska B, Kondracki M, Paduch R (1999). The effect of steroidal and non-steroidal anti-inflammatory drugs on the cellular immunity of calves with experimentally -induced local lung inflammation. Veterinary Immunology and Immunopathology, 71;1-15..
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| Paper Type | : | Research Paper |
| Title | : | Determination & Evaluation of the Effect of Different Seed Rates on the Growth and Yield of Wheat (Triticum aestivum L.) |
| Country | : | Pakistan. |
| Authors | : | Muhammad Nawaz || GhulamRasoolSidhu || Anwar Javed Wahla || Zafaryab Haidar |
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: | 10.9790/3008-1301010811 |
Abstract: Due to high annual variability in rainfall, it is very difficult to maintain agronomic practices for wheat crop. However, planting density has particular importance in production of wheat because it can be controlled at farmer level. A three yield trial was conducted at adaptive Research Farm Sheikhupura, to investigate the impact of different seeding rates on growth, yield and yield parameters of wheat(Triticum aestivumL.). Plant density, number of fertile tillers, biomass and all other yield factors significantly increased with increase in seeding rate by 12%. Four seed rates were compared: 112, 125, 136 and 150 kg ha-1. The maximum germination, productive tillers, plant height and number of grains per spike were observed under seed rate of 136 kg ha-1. However, number of grain per spike is not significantly correlated with seeding............
Keywords: Growth, Seed Rate, Seedcumfertilizerdrill, Wheat, Yield
[1] Joseph, K.D., M.M.S.B Alley., D.L. Brann, and W.D. Gravelle. 2012. Row spacing and seeding rate effects on yield and yield components of soft red winter wheat. Agron. J., vol. 77, pp. 211-214.
[2] Sikander,K.T., H. Imtiaz., M. Asif, M.Y. Mujahid, S. Muhammad, M. Qamar, and M. Asim.2009. Performance of different wheat varieties/lines as affected by different planting dates and seeding rates under high rainfall area of Potohar. Pak. J. Agri. Sci., vol. 46, pp. 102-106.
[3] Govt. of Pakistan. 2014. Economic survey of Pakistan. Government of Pakistan, Economic Advisor's Wing, Finance Div. Islamabad.
[4] Korres N.E. and R.J. Froud-Williams.2002. Weed Res., 42(6): 417.
[5] Hamid E., F.H Taj., J.Bakht.,A.W. Shah,and Shad A.A. 2002. Asian J. Plant Sci., 1: 502-506.. 1994(b); 69: 145 - 157.
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| Paper Type | : | Research Paper |
| Title | : | Medicine Storage at household level and Associated Factors in Wolaita Sodo Town Southern Ethiopia |
| Country | : | Ethiopia |
| Authors | : | Ephrem Thomas || Dr. Kassa Daka Gidebo |
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: | 10.9790/3008-1301011218 |
Abstract: Introduction Medicines are sold in health facility and peoples buy and store at home and used for treatment and prevention of disease. Medicine kept at home allows people to use irrationally and remains a key health problem in many developing countries. Objectives The purpose of this study is to assess Medicine storage at home and associated factors in Wolaita Sodo town, Southern ethiopia From February 1 March 31,2017 Southern Ethiopia. Methods and Materials A community based cross sectional study design was used. The source population of this study was all households residing in Wolaita Sodo town. Eight hundred............
Keywords: Medicine stored, Left over medicine, self medication, Health professional, Sodo Ethiopia
[1]. Jassim A. In-home drug storage and self-medication with antimicrobial drugs in Basrah, Iraq. Oman Med J. 2010;25.
[2]. WHO. The World Medicine Situation on Rational Use of Medicine 2011
[3]. Getachew E, Aragaw S, Adissie W, A. A. Antibiotic prescribing pattern in a referral hospital in Ethiopia. African Journal of Pharmacy and Pharmacology. 2013;Vol. 7(38):2657-61.
[4]. Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet. 2000;356(9237):1255-9.
[5]. WHO. Community-Based Surveillance of Antimicrobial Use and Resistance in Resource-Constrained Settings. 2009..
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| Paper Type | : | Research Paper |
| Title | : | Antibacterial Activity of Astrotrichiliaparvifolia(J.-F. Leroy &Lescot)Leaf Extracts (Meliaceae) |
| Country | : | |
| Authors | : | Rojovola Rasolofonantenaina || Rado Rasolomampianina || HerivonyOnja Andriambeloson || LovarintsoaJudicael Randriamampianina || Laurence Ralamboranto || Victor Louis Jeannoda |
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: | 10.9790/3008-1301011924 |
Abstract: This work was designed to assess the antibacterial activity of Astrotrichiliaparvifolia, a Malagasyendemic Meliaceae used in traditional medicine.Ethyl acetate and methanol extracts from leaves were tested against pathogenic germs including 4 Gram(+) and 4Gram (-) bacteriausing disk diffusion and micro dilution methods.At 1000μg/disk, both extracts showedan inhibitory activityagainstGram(+)but not Gram (-)bacteria. Bacillus cereus was the most sensitive germ with an Inhibition Zone Diameter (IZD) of 13mm and 14mm with ethyl acetate and methanol extracts respectively and Streptococcus pneumoniae the less sensitive with an IZD of 9mm and 10mm. With Minimum Inhibitory Concentration (MIC) and Minimum bactericidal concentration (MBC) values ranging from 230 to 930μg/ml, the two extracts displayed significant activity on Staphylococcus aureus, Bacillus cereus andStreptococcus pyogenes. Theyhad the same level of activity againstStreptococcus pyogenes but the methanol extract.........
Keywords: Astotrichiliaparvifolia, antibacterial activity, Meliaceae,MIC, MBC.
[1]. T.Essawi and M.J. Srour, Screening of some Palestinian medicinal plants for antibacterial activity, Ethnopharmacol., 70(3) (2000), 343-9.
[2]. V. Paritala, K.K.Chiruvella,C. Thammineni, R.G. Ghanta, A. Mohammed, Phytochemicals and antimicrobial potentials of mahogany family, RevistaBrasileira de Farmacognosia, 2015.
[3]. E.H.S. Fong, M. Tin-Wa, N.R. Farnsworth and R.H. Dobberstein, Phytochemical screening methods, Rev. Department ofpharmacognosy and pharmacology, College of pharmacy, University of Illinois, 1977.
[4]. G.B. Marini-Bettolo, S. Nicoletti and M. Patami, Plant screening by chemical and chromatographic procedure under fieldconditions, Journal of Chromatography, 218, 1981, 113-217.
[5]. M.S. Pyun and S. Shin, Antifungal effects of the volatile oils from allium plants against trichophyton species and synergism of theoils with ketoconazole, Phytomedicine, 13(6), 2006, 394-400..
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| Paper Type | : | Research Paper |
| Title | : | Evaluation of some Serum cytokine and adipokines profile in Iraqi celiac patients before and after treatment |
| Country | : | Iraq |
| Authors | : | Reema M.abed || Laith A.Yaaqoob || Israa A. Alwan || Hasan F. Samir || Ruaa A.Jasim |
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: | 10.9790/3008-1301012530 |
Abstract: Celiac disease (CD) is main gastrointestinal disease initiated by an immune reaction to gluten in genetically susceptible people. The objective of this analysis attempted to evaluate the nature as well as effect of systemic cytokine and adipokines levels within the pathophysiology of CD and also the role of therapy with gluten completely free diet on the status of its. Cytokine assays had been carried out on fifty children patients with effective CD and positive TTG IgA antibodies, and the effects were compared with healthy controls. Individuals with active CD with positive antibodies had significantly greater degrees of pro inflammatory cytokines, for example interferon- γ, tumor necrosis factor–α, IL-4 and IL-6,IL-8, and the Th -2 cytokines for example IL-5 and IL-10, in contrast to controls............
Keywords: Celiac disease, adipocytes, Cytokine profile, Gluten
[1]. Kaswala DH, Veeraraghavan G, Kelly CP, Leffler DA. Celiac disease: diagnostic standards and dilemmas. Diseases. 2015;3:86-101.
[2]. Ensari A. Gluten sensitive enteropathy (celiac disease) – controversies in diagnosis and classification. Arch Pathol Lab Med. 2010;134:826-35.
[3]. Dickson BC, Streutker CJ, Chetty R. Celiac disease: an update for pathologist. J Clin Pathol. 2006;59:1008-16.
[4]. Cataldo F, Lio D, Marino V, Scola L, Crivello A, Corazza GR, Working Group of the SIGEP, Working Group of 'Club del Tenue'. Plasma cytokine profiles in patients with celiac disease and selective IgA deficiency. Pediatr Allerg Immunol 2003;14:320–4.
[5]. Sollid LM. Molecular basis of celiac disease. Annu Rev Immunol 2000;18:53–81.
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| Paper Type | : | Research Paper |
| Title | : | Phenytoin Induced Toxic Epidermal Necrolysis: A case Report |
| Country | : | India |
| Authors | : | Nalini Pandey |
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: | 10.9790/3008-1301013133 |
Abstract: Toxic Epidermal Necrolysis is a fatal skin disease induced by the drug with 30 -40% skin detachment involved. Drugs that may induce this syndrome are such as nonsteroidal anti-inflammatory drugs, allopurinol, antimetabolites (methotrexate), antiretroviral drugs and anticonvulsants. Here is a case of 49 yrs old female of TEN induced by phenytoin. Phenytoin is an anticonvulsant drug.
Keywords: TEN, Toxic epidermal Necrolysis Phenytoin, Naranjo scale.
[1]. P Saraogi, CS Nayak, R Pereira, RS Dhurat, Inadvertent provocative oral ondansetron use leading to toxic epidermal necrolysis in an HIV-infected patient, Indian J Dermatol, 57(6), 2012, 503.
[2]. P Tiwari, R Panik, A Bhattacharya, D Ahirwar, A Chandy, Toxic epidermal necrolysis: an update, Asian Pac J Trop Dis, 3(2), 2013,85-92.
[3]. NH Shear, SP Spielberg, DM Grant et al, Differences in metabolism of sulfonamides predisposing to idiosyncratic toxicity, Ann Intern Med, 105, 1986, 179-84.
[4]. G Villada, J Roujeau, T Clerici et al, Immunopathology of toxic epidermal necrolysis, Arch Dermatol, 128, 1992,50-3.
[5]. N Shear, S Spielberg, Anticonvulsant Hypersensitivity Syndrome:In Vitro Assessment of Risk, J Clin Invest, 82, 1988,1826-32.
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| Paper Type | : | Research Paper |
| Title | : | Internal application of some Ethno medicinal plants to treat bone fractures in Eastern Ghats of India, AP. |
| Country | : | India |
| Authors | : | N.V. Jayanth Babu || P. Prayaga Murty || G.M. Narasimha Rao |
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: | 10.9790/3008-1301013437 |
Abstract: The present paper aims to documentation of the traditional wealth of medicinal plants prepared in various uses to cure the fractured bones by the tribal people of Eastern Ghats region of Andhra Pradesh. 22 plant species belongs to 20 genera and 17families used for bone fractures by the natives of Eastern Ghats of Andhra Pradesh. Information on botanical name, vernacular name, family, plant part used, mode of drug preparation, formulations and dosage were presented in this paper. Due to over exploitation of the medicinal plants in this region, plant species are going to extinct from the natural habitats or in endemic condition. So it is suggest that ex-situ and in-situ conservation is necessary to overcome the said problem.
Keywords: Bone fracture, ethno medicinal plants, Eastern Ghats of India Andhra Pradesh.
[1]. M.S. Rawat and S. Chaudhury Ethno-medico botany of Arunachal Pradesh (Nyshi & Apatani Tribes). Bishen Singh and Mahendra Pal Singh. 2005.
[2]. Tag, Hui; A.K. Das and P. Kalita, Plants used by Hill Miri of Arunachal Pradesh in ethnofisheries.Indian J. Trad. Knowl., 2005. 4(1): 57 – 64.
[3]. Legris and VM. Meher – Homji, The Eastern Ghats: Vegetation and Bilclimatic aspects. Pros. Seminar on Resources development and environment in Eastern Ghats.Andhra University. Waltair. 1982. 1-7.
[4]. S.K. Jain, The role of botanist in folklore research. Folklore 5(4): 1964. 145-150.
[5]. S.K. Jain, Observations on Ethnobotany of the tribal of Central India. In: Jain, S.K. (ed.), Glimpses of Indian Ethnobotany. Oxford & IBH, New Delhi, 1981. pp. 193 -198.
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| Paper Type | : | Research Paper |
| Title | : | A Cross-sectional Survey on Knowledge regarding Breast Cancer and Breast Self-examination among Bangladeshi Women |
| Country | : | Bangladesh |
| Authors | : | Nigar Sultana Tithi || Muhammad Asaduzzaman || Nishat Nasrin || Md. Monjur Hossan || Nahin Rahman || Nurunnahar Akter Nizum || Naharin Syeed |
|
: | 10.9790/3008-1301013844 |
Abstract: Breast cancer (BC) is considered as one of the most prevalent cancers among women in Bangladesh. The aim of the present study was to investigate the knowledge about BC, risk factor prevalence and breast self-examination (BSE) practices among female populations of Bangladesh. After taking verbal consent, 1051 females of age ≥20 years from different districts of Bangladesh were interviewed using a pre-tested questionnaire in 2015. Among the respondents, three-forth (77.74%) knew (heard or read) about BC and their main source of information was electronic media (74.54%). Most of them could identify at least one sign and symptom (73.93%) and one risk factor of BC (71.55%). But only 34.16% and 52.14% correctly identified at least one option for early detection and treatment, respectively.............
Keywords: Bangladesh; breast cancer; breast self-examination; knowledge; practice.
[1]. International Agency for Research on Cancer, Latest world cancer statistics global cancer burden rises to 14.1 million new cases in 2012: marked increase in breast cancers must be addressed, 2013 (http://www.iarc.fr/en/media-centre/pr/2013/pdfs/pr223_E.pdf).
[2]. M.S. Hossain, S. Ferdous, and H.E. Karim-Kos, Breast cancer in South Asia: a Bangladeshi perspective, Cancer Epidemiology, 38(5), 2014, 465-470.
[3]. Q. Nahar, S.E. Arifeen, K. Jamil, and P.K. Streatfield, Causes of adult female deaths in Bangladesh: findings from two national surveys, BMC Public Health, 15, 2015, 911-919.
[4]. K. Godfrey, T. Agatha, and J. Nankumbi, Breast cancer knowledge and breast self-examination practices among female university students in Kampala, Uganda: a descriptive study, Oman Medical Journal, 31 (2), 2016, 129–134.
[5]. M.N. Okobia, C.H. Bunker, F.E. Okonofua, and U. Osime, Knowledge, attitude and practice of Nigerian women towards breast cancer: a cross-sectional study, World Journal of Surgical Oncology, 4, 2006, 11-19.
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| Paper Type | : | Research Paper |
| Title | : | Glycerol-3-Phosphate Dehydrogenase Isozymes: A Computational Approach to Their Metabolic Roles in the Flight Muscles of Triatoma Infestans |
| Country | : | Argentina |
| Authors | : | Cossy Isasi S || Stroppa MM |
|
: | 10.9790/3008-1301014550 |
Abstract: Glycerol-3-phosphate dehydrogenase (GPDH) isoenzymes play different roles in Triatoma infestans flight metabolism and only differ in the C-terminal end. We studied with computational models their dynamics and interactions. Homology-modeling dynamics showed models close to minimal energy with amino acid distribution similar to crystallized structures. Radius of gyration decrease because the models presented well fitted folded structures with solvation free energy of non-polar groups increased with temperature. Heat maps suggested the need to form dimeric structures to preserve activity or that temperature could be an activity modulator. Modeled dimeric structures were similar to crystallized references............
Keywords: Docking, GPDH Isoforms, Localization, Molecular Modeling and Dynamics, Triatoma infestans
[1]. World Health Organization, 2013. Geneva: WHO. Chagas disease (American trypanosomiasis). WHO Media centre: Fact sheet N° 340.
[2]. Carcavallo RU, Jurberg J, Galindez Giron I, Lent H, 1997. Atlas of Chagas' Disease Vector in the Americas, Rio de Janeiro: Editora Fiocruz.
[3]. MC Cecere, RE Gürtler, DM Canale, R Chuit, JE Cohen. Effects of partial housing improvement and insecticide spraying on the reinfestation dynamics of Triatoma infestans in rural northwestern Argentina. Acta Trop 84, 2004, 101-116.
[4]. GC Bewley, JL Cook. Molecular structure, developmental regulation, and evolution of the gene encoding glycerol-3-phosphate dehydrogenase isozymes in Drosophila melanogaster. Isozyme 3, 1990, 341-374.
[5]. SJ O´ Brien and RJ MacIntyre. The alpha-glycerophosphate cycle in Drosophila melanogaster. Genet Aspects Genet. 71, 1972, 127–138.
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| Paper Type | : | Research Paper |
| Title | : | Effect of Dietary Counseling on Protein Energy Wasting in Hemodialysis Patients |
| Country | : | India |
| Authors | : | Dr.S.Parveen || S.Padmakar || S.Vijaya lakshmi || S.MD Yaseen shahzadi || Shaik Fouzia || Dr.K.B.Yadavendra Reddy |
|
: | 10.9790/3008-1301015159 |
Abstract: Protein Energy Wasting (PEW) is a state of decreased body stores of protein energy in the most advanced stages of chronic kidney disease maintaining hemodialysis. The main objective of this study is to assess the PEW in hemodialysis patients and to reduce the mortality rate and to improve the patient quality of life by providing dietary counselling through information leaflets. It is a hospital based concurrent interventional study was conducted for a period of six months on 60 hemodialysis patients having PEW in chronic renal failure condition. Patient demographics and laboratory data like Albumin, Cholesterol, BMI, Hemoglobin, Muscle mass was periodically collected and reviewed.............
Keywords: Chronic kidney disease (CKD) ,Hemodialysis(HD) ,Protein Energy Wasting(PEW)
[1]. Renal failure: Its treatment in current systems of medicines by Dr. Mansoor Ahmad. Pg.no.25, 26, 107-110.
[2]. Levey AS, Coresh J, Balk E, Kausz AT, Levin A, Steffes MW, et al. National Kidney Foundation practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Ann Intern Med. 2003; 139(2):137-47.
[3]. Ruan X, Guan Y. Metabolic syndrome and chronic kidney disease. J Diabetes. 2009;1(4):236-45.
[4]. Pendse S, Singh A, Zawada E. Initiation of Dialysis. In: Handbook of Dialysis. 4th edition, New York, NY; 2008:14–21
[5]. F. Esra Gunes-Medical Nutrition Therapy for Hemodialysis Patients.
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| Paper Type | : | Research Paper |
| Title | : | Continuous Flow Injection Analysis- Precipitation Reaction Of Ibuprofen With Sodium Nitro Pros Side Using Low Pressure Mercury Lamp Tube (UV-Light) And Detection Of Diverged Scattered Lights (Visible Light) At 2 X 90o Using Multi Solar Cells That Covers 2 X 100mm Distance Of 2mm Path Length |
| Country | : | Iraq |
| Authors | : | Proph. Nagam Shakir. Turkie || Hussein Fares Abd-Alrazack |
|
: | 10.9790/3008-1301016075 |
Abstract: A new, simple, fast and sensitive method has been developed for the determination of Ibuprofenin pure form and drugs (tablets)by continuous flow injection scatter light. The method was based on the reaction of the Ibuprofen with sodium nitro prosside to form a precipitate, using homemade ASNAG- fluorimeter. Optimum parameter have been studied to increase the sensitivity for developed method. The linear dynamic range for the instrument response versus Ibuprofen concentration was 0.5- 15mmol/L while the L.O.D was 33.934μg/sample from the step wise dilution for the minimum concentration of lowest concentration in the linear dynamic range of the calibration graph. The correlation coefficient (r) was 0.9804 while percentage linearity (R2%) was 96.13%. RSD% for the repeatability (n=8) was lower than 0.5% for the determination............
Keywords: Ibuprofen, flow injection scatter light, homemade instrument.
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| Paper Type | : | Research Paper |
| Title | : | Molecular based test for detection of cyanotoxins in the domestic drinking water tanks in Baghdad |
| Country | : | Iraq |
| Authors | : | Ibrahim J. Abed || Raneen N.Musbah |
|
: | 10.9790/3008-1301017681 |
Abstract: This study was conducted to assess and analyze the common cyanobacteria in the domestic drinking water tanks in Baghdad and to see if they are potentially toxigenic.The study included isolating toxic blue green algae from domestic plastic water tanks .Samples were collected during September 2016 to March 2017. The microscopic diagnosis of the samples examined showed that the predominant blue-green algae which were (Synechococcus elongatus sp., Lyngbya sp.1, Anabena aequalis, Lyngbya sp.2).In this study, four sets of primers were used to detect the genetic material of blue-green algae and detect the toxins of mycrostin, cylindrospermopsin and saxitoxin.............
Keywords: Cyanotoxin, phycocyanin, microcystin, cylindrospermopsin,saxitoxin, PCR.
[1]. H.W. Paerl, R.S. Fulton III, P.H. Moisander, and J. Dyble. Harmful freshwater algal bloom, with an emphasis on cyanobacteria. The Scentific World Journal, 1, 2001, 76–113.
[2]. T.G. Otten, and H.W. Paerl (2015). Health Effects of Toxic Cyanobacteria in U.S. Drinking and Recreational Water : Our current understanding and proposed Direction. Curr. Enviro. Rpt., 2015, 75-84.
[3]. R.W. Zurawell , H. Chen , J.M. Burke , and Prepas. Hepatotoxic cyanobacterium ; A review of the Biological Importance of Microcystins in Fresh water Environments . Toxicol. Environ. Health , 8,1,2005, 1 -37.
[4]. L. Wormer , S. Cires , D. Carrasco, and Quesada. CYlindrospermopsin is not degraded by co –occuring natural bacterial communities during a 40 day .Harmful Algae , 7, 2008, 206-213.
[5]. M. Wiese, D, P.M. Agostino, T.K. Mihali, M.C. Moffitt, and B.A. Neilan. (2010) Neurotoxic alkaloids : saxitoxin and its analogs .Mar Drug , 2010, 2185-2211.
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| Paper Type | : | Research Paper |
| Title | : | The Possible Ameliorative Role of Anethum Graveolens Against Tramadol-Induced Testicular Damage in Male Albino Rat |
| Country | : | Egypt |
| Authors | : | Fawzy M. lashin || Ibrahim M Abo laila |
|
: | 10.9790/3008-1301018290 |
Abstract: Nowadays, tramadol hydrochloride (TM) is becoming abused more popular among teens in most countries worldwide; especially between males. The aim of present study was to investigate the biochemical and histopathological profiles of subchronic model of TM toxicity on testicular functions. Experimental study, Rats was divided into three groups. Group one received saline, group two received oral doses of TM (100 mg / kg b.w), group three received anethum graveolens (AG) two hours before tramadol (NG+TM). The experiment lasted for a one month. The results showed that a significantly decrease in serum testosterone, luteinizing hormone (LH), follicle stimulating hormone (FSH), and cortisol, but elevated prolactin (PRL).............
Keywords: Tramadol, Testis, oxidative damage, Anethum graveolens, Histopathology, rats.
[1] Alvarez JG and Storey BT (1995). Differential incorporation of fatty acids into and peroxidative loss of fatty acids from phospholipids of human spermatozoa. Mol Reprod Dev 42: 334-346.
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[3] Andrade P, Visser-Vandewalle V, Hoffmann C, Steinbusch HW, Daemen MA and Hoogland G (2011). Role of TNF-alpha during central sensitization in preclinical studies. Neurol Sci. 32(5):757–71.
[4] Ashrafzadeh Takhtfooladi M, Haghighi Khiabanian Asl A, Shahzamani M, Ashrafzadeh Takhtfooladi M, Allahverdi A and Khansari M (2015b). Tramadol alleviates myocardial injury induced by acute hindlimb ischemia reperfusion in rats. Arq Bras Cardiol, 105:151-159.
[5] Bahramikia S. and Yazdanparast R. (2009). Efficacy of different fractions of Anethum graveolens leaves on serum lipoproteins and serum and liver oxidative status in experimentally induced hypercholesterolaemic rat models. Am. J. Chinese Med. 37:685-699
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| Paper Type | : | Research Paper |
| Title | : | Distribution of K1and K2 serotypes of Klebsiellapneumoniaein water isolates in compare with clinical isolates |
| Country | : | Iraq |
| Authors | : | Elaf S. Mohammed || May T. Flayyih |
|
: | 10.9790/3008-1301019195 |
Abstract: Serotypes of10 clinical isolates and 20 water isolatesofKlebsiellapneumoniaewere identified by detection of k2A and magA genes by using polymerase chain reaction (PCR) technique.k2Agene was detected in 30% (3/10) of clinical isolates and not found in water isolates, while magA gene was detected in 60% (6/10) of clinical isolates and 15% (3/20)in water isolates. 20% of clinical isolates found to be having both magA and k2Agene. The results in the current study showed that clinical isolates distributed according to their serotypes in to four groups K1(magA positive), K2(k2A positive), K1/K2(magA& k2A positive) and non K1/K2(magA& k2A negative) serotypes, but K1 serotype was more prevalence than other serotypes, while water isolates distributed in to K1(magA positive) and non K1/K2(magA& k2A negative) serotypes, but non K1/K2 serotype was more prevalence than K1 serotype.
Keywords: Klebsiellapneumoniae, water, k2A,magA,serotype.
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| Paper Type | : | Research Paper |
| Title | : | Chemical Composition And Larvicidal Activity Of Essential Oil FromLippiajavanicaagainstRhipicephalusappendiculatuslarvae |
| Country | : | Kenya |
| Authors | : | Caroline J. Kosgei || Josphat C. Matasyoh || Charles M. Mwendia |
|
: | 10.9790/3008-1301019699 |
Abstract: Animal ectoparasites particularly ticks contribute majorly to decreased productivity in the livestock industry globally, due to diseases they transmit. This study evaluated the larvicidal activity of essential oil of Lippiajavanicaleaves against larvae of Rhipicephalusappendiculatus. The oil was obtained by hydro-distillation of fresh leaves and oil components analysedusing Gas Chromatography-Mass Spectrometry (GC-MS). Major components in the oil were monoterpenes as shown by the high percentage of Artemisia ketone (49.52%), m-tert-Butylphenol (8.73%), Linalool (4.43%), beta-myrecene (3.13%), Targetone (2.85%) and Isopiperitenone (2.13%). Sesquiterpenes constituted only 6.06% of the total oil.............
Keywords: Cytotoxicity, Phytochemicals, Bioassay
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