iosr-JPBS   Volume-13 ~ Issue-3 ~ May-June 2018

Abstract: Nurses play prominent role in the healthcare system through advanced care of patients with chronic illness. This study examined the impact of demographic variables on nurses participation in integrated care of chronically ill patients. Purposive sampling technique was used to select 240 nurses working in secondary and tertiary health institutions in Anambra State of Nigeria. Two research questions and three null hypotheses guided the study. The instrument used for data collection was Questionnaire on Nursing Interventions in Integrated Management of Chronically ill Patients. Standard descriptive statistics was used to summarize the variables. Percentages were used to answer the research questions, while chi-square, Mann- Whitney-U and Wilcoxon tests were used in testing the null hypotheses at 0.01 level of significance.............

Keywords: Chronic illness, Demographic variables, Integrated care, Nurses participation.

Abstract: l'OCT du segment antérieur est un examen anodin, facile à réaliser et qui permet de suivre certaines affections du segment antérieur de manière précise et d'éviter le recours à certaines thérapeutiques agressives. Nous rapportons le cas d'un patient admis pour perforation cornéenne compliquant un syndrome sec ayant bénéficié d'un traitement médical avec pose de lentille thérapeutique. Un suivi régulier à été possible à l'aide de l'OCT du segment antérieur permettant ainsi de noter la bonne amélioration sous traitement.

Abstract: This study was aimed to develop solid lipid nanoparticles (SLNs) as well as nanostructured lipid carriers (NLCs) and evaluate their potential as carrier systems for topical delivery of benzocaine to improve the drug entrapment efficiency and sustained release. SLNs and NLCs were prepared by high shear homogenization followed by ultrasonication method, using different types of solid lipids such as glyceryl monostearate, stearic acid and Compritol 888 ATO. Isopropyl myristate, as a liquid lipid in formulation of NLCs was used in different ratios to study the influence of liquid lipid content on the particle size, entrapment efficiency and zeta potential of the formulated benzocaine loaded lipid nanoparticles. The results indicated that entrapment efficiency and particle size depend on the concentration and the lipid mixture employed. The selected NLCs (NLC6) was further incorporated in 5% carboxymethyl............

Keywords: Benzocaine, Nanostructured lipid carriers, Solid lipid nanoparticles, Topical delivery, Hydrogel.

Abstract: Objective: The present study was conducted to analyze the current prescription pattern and cost analysis of antihypertensive drugs in hypertensive patients in a tertiary care hospital. Materials and Methods: A retrospective cross-sectional study was conducted in tertiary care hospital, Kadapa, A.P., and India for six months and utilized 600 prescriptions for the analysis. The data analyzed from the prescription included patients demographics, stage of hypertension according to JNC VII guidelines, type of drug therapy, class of anti-hypertensive, and cost effectiveness of therapy. Drug Percentage cost variation calculated, using the Minimum and Maximum cost of individual drug. The average maximum and minimum costs were calculated and compared with average range of blood pressure. Statistical analysis was performed by using unpaired t-test..........

Keywords: FDC, Unpaired t-test, % cost variation, Telmisartan, Hydrochlorothiazide..

Abstract: Objective: to verify the effects of pilocarpine mouthwash on vocal acoustic parameters and salivation of healthy volunteers. Method: a clinical, randomized, placebo-controlled (saline) trial was conducted with 36 healthy individuals. Salivation was measured before and 15, 30, 45, 60 and 75 minutes after the administration of pilocarpine solutions (1% or 2%) or saline solution control. Blood pressure, heart rate, voice acoustic analysis, and assessment of symptoms resulting from the use of pilocarpine by visual analogue scale were measured before and at 75 minutes after treatment. Results: the increase in salivation was dosed (p = 0.021) and time-dependent. The 2% pilocarpine solution showed........

Keywords: Pilocarpine, Salivation, Xerostomia, Vocal quality

Abstract: Background Traditionally, in Iraq WE evaluated the degree of neuromuscular blockade during and after anesthesia using clinical criteria alone. which is inaccurate to assess recovery from neuromuscular block (NMB) which is imperative for the patient to have full control of pharyngeal and respiratory muscles. The train-of-4 (TOF) ratio should return to at least 0.90 to exclude potentially clinically significant postoperative residual block. The time gap between clinical recovery (subjective) by using a PNS until objective recovery i.e TOF ratio has returned to _0.90 can be considered "the potentially unsafe period of recovery. AimTo determine the time difference( from giving AD till reach 90% TOF readings..........

Keywords: TOF, PNS; Fade; NMBA; Extubation; Reversal.

Abstract: Oil spill occurs frequently all around the world which adversely affect the environment. Thus a low cost and environmentally friendly bioremediation could be an alternative way to solve the oil pollution problem. The cyanobacteria Anabaena variabilis used in this study to investigate their ability to grow and degrade different concentrations of crude oil. It was found that the growth of cyanobacterium Anabaena variabilis in the presence of crude oil as the sole carbon source increases at the same rate as the control sample. Results obtained from FTIR analysis showed a high ratio analysis of hydrocarbon compounds through the changes that occurred in the composition of the hydrocarbon. GC-MS analysis.........

Keywords: Crude oil, Biodegradation, Cyanobacteria, FTIR, GC-MS

Abstract: Waste water is any water that has been adversely affected in quality by anthropogenic influence. Many pharmaceutical industries is responsible to generates toxic effluent. The waste water generated from these industries possess solids, biodegradable and nonbiodegradable organic compounds. Pharmaceutical compounds typically produced in batch process leading to the presence of a wide variety of products in waste water which are generated in different operations. Various sources of pharmaceutical industries are different sectors of Active pharmaceutical ingredients (API), bulk drugs, and formulation department. Pharmaceutical residues and/or metabolites are usually detected in the environment at trace levels but even that low concentration levels but can induce toxic effects.........

Keywords: Waste water, Biochemical oxygen demand, Total dissolved solids.

Abstract: Liver plays a central role in the metabolism and excretion of xenobiotic which makes it highly susceptible to their adverse effects. The aim of the present work is to evaluate the possible protective effect of Curcuma longa powdered rhizome and /or Nigella sativa powdered seeds against hepatotoxicity of Rifampicin, Isoniazid and Acetaminophen combination in rats. Rats were randomly allocated into 10 groups, all groups were administered the drugs orally for 21 days and the treatments started one hour before drugs administration according to the following scheme:Group (1): Normal group received 2% tween 80.Group (2): Received Curcuma longa (200 mg/kg) .Group (3): Received Nigella sativa (250 mg/Kg) Group (4): Received Curcuma longa + Nigella sativa Group (5): Received........

Keywords: Curcuma longa, Nigella sativa, Rifampicin, Isoniazid and Acetaminophen, Casp-3 , TNF-α hepatotoxicity.

Abstract: Lymphatic filairasis has remained a public health problem,especially in tropical countries of the world. Despite several efforts over the years to eliminate it both by the World Health Organization (WHO) and Non-governmental organizations( NGOs). The prevalence of lymphatic filairiasis was carried out among 400 subjects aged 18 years and above in Ekpri-Ikang, Ikang and Ebot-20 Communities in Bakassi Local Government Area, Cross River State. Of the 400 samples collected 184 (46%) were males while 216(54%) were females. Structured questionnaires were administered to all the participants and their informed consents was also sought and obtained. Two millilitres of venous blood was obtained from each of the consented participants between the hours of 9pm and 10 pm daily. The presence of WuchereriabancroftiWb 123 antigen in the blood was determined using SD bioline IgG4 antigen kit while the presence of micro filaria was determined using knott's concentration method and microscopy......

Abstract: Fenugreek is an annual plant of the family Fabaceae with leaves consisting of three small obviate to oblong leaflets. It is cultivated worldwide as a semiarid crop. Its seeds and leaves are common ingredients in dishes from the Indian subcontinent, its use as a food ingredient in small quantities is safe. They are often roasted to reduce inherent bitterness and to enhance flavour. Fenugreek is sometimes used as animal feed. It provides a green fodder palatable to ruminants. The seeds are also used to feed fish and domestic rabbits.

KEY WORKS: Fenugreek, Fabaceae, Obviate Oblong

Abstract: Folklore Medicine uses in Gangolu village, Bhadradri Kothagudeum District, Telangana State, which is mainly occupied by Koya tribes revealed that some medicinally important plants were used by herbal healers (ages between 54 - 80 years). In the present study, local name, scientific name, family, habit, uses have been identified. Folklore Medicine studies were conducted particularly and dense forest where the koya tribal community inhabits.....

Keywords: Folklore Medicine