Abstract: This study was carried out to determine the antibacterial effects of saponins from Prosopis africana and Ziziphus abyssinica. Saponins were isolated using ethanol, diethyl ether and isopropanol as solvents, and evaluated for antimicrobial activity against medically important bacteria (S. aureus, and E. coli), using nutrient agar. Antimicrobial activity was performed using paper disc method. The saponin isolated from P. africana leaves was active and showed the highest zone of inhibition at concentration 30mg/ml against S. aureus and E. coli. The saponin isolated from Z. abyssinica leaves showed the highest zone of inhibition at concentration 10 and 30mg/ml respectively..........
Key Words: Extract; Prosopis Africana; Zizipus abyssinica; Saponins; Inhibition
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