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| Paper Type | : | Research Paper |
| Title | : | Lipid –peroxidation & Non-enzymatic antioxidant (Vitamin E & Vitamin C) serum levels in Anemic Rheumatoid arthritis patients |
| Country | : | India |
| Authors | : | Dr. Shweta Dwivedi, Dr. Shreesh Singh, Dr. Geeta Jaiswal |
 |
: | 10.9790/3008-09110103  |
Abstract: Rheumatoid arthritis (RA) is a chronic multisystem disease with an unknown etiology affecting about 1% of the world's population. Anemia is a frequently occurring extra articular manifestation of RA, being mostly of the normochromic & normocytic type. The aim of our study to assess and affirm whether the increased oxidative stress in inflamed joints is reflected by lipid-peroxidation? Also to check the alteration in levels of non –enzymatic antioxidant (vitamin E & vitamin C) in RA with Anemia. 100 patients with RA and 100 healthy individual were included in this study. A level of malonaldehyde (MDA), a lipid –peroxidation marker was measured by Utley's method. Non enzymatic antioxidant vitamin E and vitamin C was assayed in plasma/ serum by Shami Hashim & Carl A Burtis method. The levels of MDA were significantly increased (P<0.001) in RA as compared to control. Whereas levels of non-enzymatic antioxidant (Vitamin E & Vitamin C) were decreased in patients as compared to control. It is statistically significant (P<0.001). There was a raised oxidative stress and decreased non-enzymatic antioxidant (Vitamin E & Vitamin C) in anemic rheumatoid arthritis patients. These changes are probably due to efforts for reducing lipid-peroxidation and hence to lower tissue damage.
Keywords: Arthritis; lipid-peroxidation; anemia; oxidative stress; rheumatoid arthritis.
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| Paper Type | : | Research Paper |
| Title | : | An isocratic normal-phase high-performance liquid chromatographic method for the simultaneous determination of benzoyl peroxide and benzoic acid in one pharmaceutical preparation and their stability in different solvents |
| Country | : | Iraq |
| Authors | : | Hazim Hamid Hamdu |
|
: | 10.9790/3008-09110412 |
Abstract: A normal-phase high-performance liquid chromatographic method was developed for the simultaneous determination of benzoyl peroxide (BPO) and benzoic acid (BA). The compounds are separated on a normal phase column Eurospher-100, c18.4.6mmID. The mobile phase is methanol - water (65 + 35, v/v). Solutions are injected into the chromatographic system under isocratic conditions at a constant flow rate of 1 mL /min with UV detection at 240 nm. Analysis of stability samples in deferent solvents showed formation of BPO from BA when it dissolved in ether or methanol and very low degradation of BPO to BA when it dissolved in ether compare with when it dissolved in methanol.
Key Words: benzoic acid, benzoyl peroxide, HPLC, normal phase, solvents
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| Paper Type | : | Research Paper |
| Title | : | Studies on an antimicrobial activity of metal (Mn, Fe, Co, Ni, and Cu) chelates of 1, 2 naphthoquinone 1-oxime |
| Country | : | India |
| Authors | : | V. B. Jadhav, N. R. Gonewar, K. D. Jadhav, R. G. Sarawadekar |
|
: | 10.9790/3008-09111319 |
Abstract: Transition metal chelates of the type M [NQO] 2 where M = Mn, Fe, Co,Ni, Cu: NQO = 1, 2 napthoquinone 1-oxime have been synthesized. X-ray studies have been carried out for Mn and Cu chelate of 1, 2 napthoquinone 1-oxime and the chelate of manganese belongs to Triclinic, a = 6.3580, b = 18.9591 c = 7.5697 A0, α = 100.429, β = 74.757, γ = 66.998, and copper chelate belongs to triclinic, a = 7.5528, b = 5.8689 c = 13.6719 A0, α = 63.541, β = 92.028, γ = 103.795. Their particle sizes are in the range of 15-42 nm. All chelates have been characterized by modern methods such as elemental analysis, FTIR and Electronic spectra.Scanning electron microscopy of chelates was carried out. The ligand and the metal chelates have been screened for antimicrobial activity on gram positive, gram negative bacteria and fungi. The results are compared with cisplatin as standard chemotherapy agent.Mechanism of hydrolysis of metalchelates is discussed.
Key Words: 1-2 naphthoquinone1-oxime, Antimicrobial activity, Electronic spectra, X-ray diffraction, IR, SEM.
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| Paper Type | : | Research Paper |
| Title | : | Diversity of Ornamental Fishes in Lower Manair Dam at Karimnagar Dt. Andhra Pradesh |
| Country | : | India |
| Authors | : | K. Rama Rao |
|
: | 10.9790/3008-09112024 |
Abstract: The freshwater ornamental fishes in the Lower Manair Dam were studied from August-2012 toJuly-2013. Samples were collected every week with help of local fishermen by using fishing nets and bamboo traps. In one year study period, 53 species of ornamental fishes were recorded in Lower Manair Dam. The recorded fishes belong to 8 orders, out of these orders cypriniformes was dominant with 23 species contributes 43.40% in 2 families followed by Perciformes 11 species (20.76%) 6 families, Siluriformes 9 species (16.98%) in 5 families, Channiformes 4 species (7.85%) in 1 family, Beloniformes 2 species (3.77%) 2 families, Angulliformes 2 species (3.77%) 1 family, Osteoglossiformes one species and Mogiliformes one species (1.87%) in each family. Of these, 13 species were abundant, 13 species were common, 19 species were moderate and seven species were rare. Family cyprinidae was dominant with 10 genera and genus Puntius was dominant with 5 species followed by other species, IUCN (2013.2) and CAMP (1998) conservation status of each fish was listed.
Key Words: Ornamental fishes, Cypriniformes, IUCN, CAMP.
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[6] Chakravartty,P., Chakravartty, M. & Sharma, S. (2012). A Survey on the Fish Diversity with Special Reference to the Classified Ornamental Fishes and their Prospects in the Kalpa Beel of Barpeta District. The Science Probe, 1.1(2): 12-21.
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| Paper Type | : | Research Paper |
| Title | : | Aquaculture Research Issues, Opportunities and Current Priorities in Nigeria |
| Country | : | Nigeria |
| Authors | : | Ugoala, Emeka |
|
: | 10.9790/3008-09112539 |
Abstract: Fisheries and aquaculture continue to be a very important source of food, employment and revenue in many countries. The growth of commercial aquaculture has brought with it more intensified methods of production. Against a continuing background of diminishing and over-exploited aquatic resources, aquaculture has been widely held up as panacea to the problem of providing a growing world population with ever-increasing amounts of fish for consumption. While innovative aquaculture involves the applications of new and more effective ways or solutions for aquaculture management, there may be interventions related to breeding and farming techniques, aquatic environment management, disease control or animal health monitoring, nutrition and feed management of the cultured organisms, genetics and biotechnological tools which directly or indirectly play roles in improvement of aquaculture production in an environment-friendly and sustainable manner. Aquatic Resource and their sustainable management for biodiversity conservation constitute a multi-facetted complex system. The challenges are manifold.
Key Words: Management; Pollution; Environment.
[1]. Aluko, P. O. and Olufeagba, S. O. (1999). Genetics and food security in Nigeria in the 21st century. Genetically modified fishes; risk and prospects. P.205-206. Genetic Society of Nigeria Annual Conference.
[2]. Aluko, P. O and Olufeagba, S. O (2000).Genetically modified fish: Risks and Prospects. Genetic and food security in Nigeria, 205-208.
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[5]. Bombatta, H. A.; Ajepe, R. G.; Hammed, A. M. and Jimoh, A. A. (2005).Characterization of an ecotype cichlid commonly referred to as 'wesafu' endemic to Epe Lagoon Lagos, Nigeria. World aquaculture 36 (4).
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| Paper Type | : | Research Paper |
| Title | : | Role of Robotic Asistancefor CT Guided Interventions |
| Country | : | India |
| Authors | : | Dr. vasudha Jadhav, Dr. Nikit Mehta, Dr. Pradeep Kulkarni, Dr. Ranjeet sinha jadhav |
|
: | 10.9790/3008-09114045 |
Abstract: Robot attached to Computed Tomography is recently a new modality in Radiology and Pain practices. Use of robotic assistance technique has significant benefits over conventional techniques {1} . It is very helpful in assessing depth of structures like vessels, nerves, tissues, bony structures. It is very help full in biopsy procedures ,in FNAC[2},in RF ablation procedures , in drainage of fluids ,in giving various types of nerve blocks for pain relief. A robot can hold ,orient and guide a needle with CT and fluoroscopic guidance . Physician's radiation exposure is also negligiable during CT fluoroscopy . The source of information is pub med.
Key Words: Computed Tomography, Robotic arm, FNAC.
[1]. N.V.Tsekos, J, Shudy ,E ,Yacoub ,P.v. Tsekos and I.G.Koutlas , Development of a robotic device for MRI guided interventions in the breast ,‖Presented at 2nd IEEE international symposium ‗' ON Bioinformatics and Bioengineering ,Washington DC ,2001.
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| Paper Type | : | Research Paper |
| Title | : | Protective effect of tulsi and levetiracetam on memory impairment induced by pregabalin on mice |
| Country | : | India |
| Authors | : | Asher John Mohan, Krishna K. L., Jisham K. M., Seema Mehdi, Ramesh B. Nidavani |
|
: | 10.9790/3008-09114652 |
Abstract: Memory impairment is the major concern of antiepileptic therapy. This study was undertaken to evaluate the memory impairment potential of Pregabalin (PGBL) and to assess the protective effect of hydro alcoholic extract of Ocimum sanctum leaves (OSHAE) and levetiracetam (LEV). Preliminary phytochemical screening and in-vitro antioxidant activity of OSHAE were done. Memory impairment induced by PGBL was evaluated by Morris water maze (MWM) test using mice as animal model. The animals were observed for Escape Latency Time (ELT) and Time Spent in Target Quadrant (TSTQ). OSHAE exhibited potent antioxidant and free radical scavenging activity. Chronic administration of PGBL was found to induce memory impairment by increasing ELT and decreasing TSTQ when compared to normal animals. Memory impairment of PGBL was restored significantly by co-administration of OSHAE and LEV along with potentiation of anticonvulsant activity of PGBL. PGBL alone treated animals have shown more acetylcholinesterase (AChE) level when compared with normal animals where as co-administration of OS and LEV produced a decrease in AChE levels when compared to vehicle and PGBL treated group. The above study can be used as a reference to correct anti-epileptic drug (AED) induced memory impairment by co-administration of nootropics without compromising on its antiepileptic potential.
Key Words: Levetiracetam, Memory impairment, Ocimum sanctum, Pregabalin.
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| Paper Type | : | Research Paper |
| Title | : | Documentation and Assessment on Knowledge of Ethno-Medicinal Practitioners: A Case Study on Local Meetei Healers of Manipur |
| Country | : | India |
| Authors | : | D. S. Ningombam, S. P. Devi, P. K. Singh, A. Pinokiyo, Bisheswori Thongam |
|
: | 10.9790/3008-09115370 |
Abstract: The traditional medicinal healers of the state Manipur are generally known as Maibas for male health practioner and Maibis in case of female health practioner. Since time immemorial they are involved in prescribing folk-medicine with the help of herbal-medicine or mystic incantation. An investigation on 41 local Maiba and Maibi of Meetei community of Manipur is carried out to find reliability of their knowledge, and tested if these were related significantly to age, literacy, hesitation, results of their treatment, doses and to document such know ledges based on a total of 205 locally available medicinal plant spp. belonging to 87 families used for treating 18 major diseases classes. Traditional medicinal practioners were also interviewed to gather information regarding knowledge of folk medicinal system, diagnostic system of ailments, classification of folk medicinal system, nomenclatural system and uses of medicinal plants found in Manipur as a remedy for various primary health complaints. In the present study three types folk medicinal system were recorded. The diagnostic system is bases on pulsation and symptoms.
Key Words: Manipuris, Maibas,Meetei, mangtak, practioner, ethno medicinal plants.
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| Paper Type | : | Research Paper |
| Title | : | Curative efficacy of methanolic extract of Monochoria vaginalis against Carbontetra chloride (CCl4) induced liver fibrosis in male wistar rats |
| Country | : | India |
| Authors | : | Bhaskara Kurup Latha, Mukalel Sankunni Latha |
|
: | 10.9790/3008-09117176 |
Abstract: The traditional medicine involves the use of different plant extracts or the bioactive constituents and provide cure to many ailments of mankind. Carbontetra chloride (CCl4) induced hepatic fibrosis is a well-established animal model to study the pathogenesis and therapy of chronic liver injury. Objectives: This study was aimed to evaluate antifibrotic efficacy of methanolic extract of Monochoria vaginalis (MEMV) on CCl4 induced liver injury in rats. Methods: Hepatic fibrosis was induced in male wistar rats by oral administration of CCl4 (150μl/100g rat weight) twice a week for 10 weeks. In curative treatment M.vaginals and Silymarin at doses of 100mg, 200mg and 50mg/kg b.wt respectively were administered orally for 2 weeks after the establishment of fibrosis for 10 weeks. Results: CCl4 administration caused a significant decrease in body weight and resulted in significantly increased levels of aspartate transaminase (AST), alanine transaminase (ALT), alkaline phosphatase (ALP),thiobarbituric acid reactive substances (TBARS), conjugated dienes (CD) and hydroxyproline (HP). MEMV at the dose of 200mg/kg b.wt prevented or reversed the decline in body weight and the levels of marker enzymes. The treatment reduced the tissue levels of TBARS, CD & hydroxyproline, and increased the levels of tissue GSH, serum total protein and albumin in chronically treated rats. Histopathological changes of hepatic lesions induced were significantly (p ≤ 0.05) improved by treatment with M.vaginalis. Conclusions:.The results indicate the antifibrotic effect of MEMV and thus scientifically validated the use of root part in traditional medicine for hepatic disorders.
Key Words: Carbontetra choloride, hepatic fibrosis, histopathology, hydroxyproline, Monochoria vaginalis.
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| Paper Type | : | Research Paper |
| Title | : | Common Uropathogens That Cause Utis In Enugu Area And Their Sensitivity To Ciprofloxacin |
| Country | : | Nigeria |
| Authors | : | Onyemelukwe, NF, Nwokocha, ARC |
|
: | 10.9790/3008-09117780 |
Abstract: Introduction: The study aims at assessing the common bacterial agents causing urinary tract infections (UTI) in Enugu and environs and to examine the incidence of Ciprofloxacin resistance in the strains of bacteria isolated from patients suspected to have UTI over an 18 month period. Methods: Ciprofloxacin was evaluated along with other commonly used antibiotics against a total of 147 bacterial isolates obtained in pure cultures from urine samples. The patients were all out-patients seen attending urban and rural health centres in Enugu and environs with signs and symptoms suggestive of UTI. The antibiogram was done using the disk difference method.
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