iosr-JDMS   Volume-21 ~ Issue-8 ~ Aug. 2022

Abstract: Background:- Following a radical cancer surgery resection, reconstruction of the defect by micro vascular free flaps seem to be ideal procedures for reconstruction in head and neck region. These provide ample amount of tissue for large and even complex defects and enhance reconstruction. Microvascular free flaps have also provided flexibility for the onco surgeon for extensive surgical resections. Method :- There were about 48 free flap performed in a span of 3 months from December 2020 till February 2021 in the surgical oncology department of kiran multispecialty hospital , Surat. For reconstruction of both bony and soft tissue defect. The choice of free flaps were the free fibula flap along with radial and Anterio-lateral thigh flap. Results:- the success rate of the viability......

[1]. Seidenberg B. Immediate reconstruction of the cervical esophagus by a revascularized isolated jejunal segment. Ann Surg1959;149:162.
[2]. Taylor GI, Razaboni RM. Michel Salmon's anatomical studies. Book 1. Arteries of the muscles of the extremities and the trunk. St Louis: Quality Medical Publishing; 1994.
[3]. O'Brien BMcC. Microvascular reconstructive surgery. Edinburgh, London, New York: Churchill Livingstone; 1977.
[4]. Kroll SS, Schusterman MA, Reece GP. Comparison of the rectus abdominis free flap with the pectoralis major myocutaneous flap for reconstructions in the head and neck. Am J Surg1992;164:615-8.
[5]. Kroll SS, Schusterman MA, Reece GP. Costs and complications in mandibular reconstruction. Ann PlastSurg1992;29:341-7.

Abstract: Introduction : Palmoplantar dermatoses (PPD) include specific skin diseases affecting palms and soles which are frequently encountered conditions in the dermatological practice. Palmoplantar dermatoses have major impact on our personal as well occupational life and its early detection and treatment is necessary to maintain our livelihood. However, there is paucity of specific as well comprehensive literature revealing characteristics of palmoplantar dermatoses. Method : This was a hospital based descriptive cross sectional study, conducted in the department of Dermatology and Venereology of Tribhuvan University, Teaching Hospital. The study duration was from November 2020 to October 2021. Total....

Keywords : Palmoplantar dermatoses, eczema, palmoplantar psoriasis, diagnosis, analysis

[1]. Singh A, Zaidi S. Dermatoglyphics: A Brief Review. Int J Adv Integr Med Sci. 2016;1(3):111–5.
[2]. Rittié L, Sachs D, Orringer J, Voorhees J, Fisher G. Eccrine Sweat Glands are Major Contributors to Reepithelialization of Human Wounds. Am J Pathol. 2013;182(1):163–70.
[3]. Li S, Zheng X, Nie Y, Chen W, Liu Z, Tao Y, et al. Defining key genes regulating morphogenesis of apocrine sweat gland in sheepskin. Front Genet. 2019;10(JAN):1–16.
[4]. Motswaledi MH. Skin disorders affecting the feet. South African Fam Pract. 2015;57(5):34–8.
[5]. Hongal AA, Rajashekhar N, Gejje S. Palmoplantar dermatoses – A clinical study of 300 cases. J Clin Diagnostic Res. 2016;10(8):4–7..

Abstract: BACKGROUND: Non-specific low back pain is defined as low back pain not owing to a known specific cause / pathology. 90% LBP patients are having Non-specific causes. Low back is very essential in our daily activities like - lifting, carrying, supporting upright posture which is essential for every person out there regardless of the job they are serving. As there is high prevalence of having tight hamstring in patients complaining of low back pain. So, the purpose of study was to investigate the comparative Effect of "Mulligan's BLR and Self hamstring MFR in young adults with non-specific low back pain......

Keywords: Hamstring tightness,Mulligan BLR technique, Nonspecific low back pain, Self Hamstring MFR, Young adults.

[1]. AnandHeggannavar, Santosh Metgud, Sanaja.K.S (2019)- Conducted a study to comapare the effect of Mulliga's BLR versus IASTM in patients with non-specific low back pain,IJHSR , Karnataka,(2019)
[2]. Phadnis and Bhave SM2 Comparative Study of Mulligan Bent Leg Raise vs. Hold Relax Proprioceptive Neuromuscular Facilitation on Hamstring Tightness in High School Student, journal of physical therapy and rehab, Nagpur,3(1), 2018
[3]. Wong KK, Chai HM, Chen YJ, Wang CL, Shau YW, Wang SF. Mechanical deformation of posterior thoracolumbar fascia after myofascial release in healthy men: a study of dynamic ultra-sound imaging. Musculoskeletal SciPract, physical therapy rehabilitation, republic of korea 6(1), 2017;27:124-30
[4]. SudhirGanesan, Anita Shankar Acharya, Shankar Acharya Prevalence and risk factors for low back pain in 1355 young adults: A cross sectional study.Asian Spine Journal. Volume 11(4); 2017
[5]. Beardsley C, Škarabot J. Effects of self-myofascial release: a systematic review. J BodywMovTher, elsevier;19(4):747-58, 2015

Abstract: Background: Despite a growing understanding of coping styles and its determinants, little is known about the mediating role of personality traits in linking depression and coping styles (problem focused and emotion focused). The purpose of this study was to evaluate the mediating role of personality traits in the relationship between depression and coping among pregnant women. Materials and Methods: It was a cross-sectional study involving 200 participants receiving antenatal care at the Enugu State University Teaching Hospital (ESUTH) Enugu, Nigeria between the ages of 17 and 41. Data were obtained using the Hospital Anxiety and Depression Scale (HADS), Brief Coping Scale (BCS) and the Big Five Inventory (BFI). SPSS Version 21/ Process Macro and Pearson Correlation Tests were used to analyze the data. Results: Both coping styles and......

Keywords: Antenatal depression, Personality Trait, Coping style, Mediating role

[1]. Norbeck JS, Anderson NJ. Life stress, social support, and anxiety in mid- and late-pregnancy among low income women. Research in Nursing & Health.1989; 12(5):281–287.
[2]. Ritter C, Hobfoll SE, Lavin J, Cameron RP, Hulsizer MR. Stress, psychosocial resources, and depressive symptomatology during pregnancy in low-income, inner-city
[3]. women. Health Psychology. 2000; 19(6):576–585.
[4]. Glazier, Elgar, Goel & Holzapfel. Stress, social support and emotional distress in a community of pregnant women. Journal of psychosomatic obstetrics & Gynecology. 2004; volume 25 – issue 3-4.
[5]. Vigod & Wilson. Depression in pregnancy. Clinical review BMJ. 2016, 352 doi

Abstract: Background: Craniocerebral trauma is a major cause of death and disability around the world. In most Nigerian cities, poor conditions of roads and increasing urban congestion have led to more road traffic accidents (RTAs). Computed tomography (CT) is an essential tool in the management of head trauma. This study evaluated the CT imaging findings in patients presenting with craniocerebral trauma. Materials and methods: This was a retrospective study which involved radiological CT reports of 139 patients conducted at a tertiary hospital in Uyo metropolis, Akwa Ibom state, Nigeria. Only records of patients who underwent non-contrast cranial CT following head trauma were included this study. Data generated was analysed using descriptive statistics.......

Keywords: Head trauma, TBI, intracranial haemorrhage, brain injury

[1]. Onwuchekwa CR, Alazigha NS. Computed tomography patterns of traumatic head injury in Niger Delta, Nigeria: A multicenter evaluation. International Journal of Critical Illness andInjury Science. 2017, 7: 150-155.
[2]. Akanji AO, Akinola RA, Balogun BO, Akano AO, Atalabi OM, Akinkunmi MAN, Awosanya GOG. Computerized tomography scan and head injury: The experience in a tertiary hospital in Nigeria: A cross sectional study. Medical Practice and Review. 2015, 6(1): 1-15.
[3]. Ohaegbulam SC, Mezue WC, Ndubuisi CA, Erechukwu UA, Ani CO. Cranial computed tomography findings in head trauma patients in Enugu, Nigeria. Surg Neurol Int. 2011, 2: 182. Doi: 10.4103/2152-7806.91137.
[4]. Dewan MC, Rattani A, Gupta S, Baticulon RE, Hung YC, Punchak M, Agrawal A, Adeleye AO, Shrime MG, Rubiano AM, Rosenfeld JV, Park KB. Estimating the global incidence of traumatic brain injury. Journal of Neurosurgery. 2018, 1: 1-18.
[5]. Mata-Mbemba D, Mugikura S, Nakagawa A. Early CT findings to predict early death in patients with traumatic brain injury: Marshall and Rotterdam CT scoring systems compared in the major academic tertiary care hospital in northeastern Japan. Academic Radiology. 2014, 21(5): 605-11

Abstract: Laurence-Moon-Bardet-Biedl syndrome is a rare ciliopathic autosomal recessive disorder mostly seen in children of consanguineous marriages. It is identified by its characteristic features namely retinitis pigmentosa, obesity, mental retardation and polydactyly. Herein, we report a case of a 24 year old female presenting with features of renal dysfunction like anemia, decreased urine output, vit D3 deficiency and further examination was found to show features of LMBBS i.e retinitis pigmentosa, learning disabilities, polydactyly and obesity. It is important for the physicians to be aware of this syndrome for early identification. Multidisciplinary approach and periodic follow up can decrease the morbidity and mortality of the patient.

[1]. Khan BA, Shahid A, Nazir MB, Khan KS, Punshi A. Laurence-Moon-Bardet-Biedl Syndrome: A Case Report. Cureus [Internet]. 2019 Sep 10 [cited 2022 Jan 16];11(9). Available from: https://www.cureus.com/articles/19663-laurence-moon-bardet-biedl-syndrome-a-case-report
[2]. Parakh R, Nairy DM. Bardet-Biedl Syndrome with End Stage Renal Disease. Iran J Med Sci. 2016 Nov;41(6):539–42.
[3]. Qadar LT, Ahmed ZM, Munawar M, Hasan CA, Iqbal SU. Laurence-Moon-Bardet-Biedl Syndrome with Coexisting Abdominal Distension and Positive Fluid Thrill: A Rare Manifestation Reported in Karachi, Pakistan. Cureus. 11(6):e4885
[4]. Khan SA, Muhammad N, Khan MA, Kamal A, Rehman ZU, Khan S. Genetics of human Bardet-Biedl syndrome, an updates. Clin Genet. 2016 Jul;90(1):3–15.
[5]. Abbasi A, Butt N, Sultan B, Munir SM. Hypokalemic paralysis and megaloblastic anaemia in Laurence-Moon-Bardet-Biedl syndrome. J Coll Physicians Surg--Pak JCPSP. 2009 Mar;19(3):186–8.

Abstract: Background: The rising burden of lifestyle risk factors for non-communicable disease among adolescents is a major public health problem worldwide. Objectives: 1. To estimate the prevalence of lifestyles risk factors among school adolescents 2. To determine the role of gender on lifestyles risk factors. 3. To study the association of lifestyle risk factors with high Body Mass Index (BMI) status. Methodology: This Cross sectional study was conducted among school going adolescents of three randomly selected schools of Agartala. Multistage stratified random sampling procedure was adopted and information was collected using global school based student......

Keywords: lifestyles risk factors, adolescent health, school adolescents, physical activity, dietary habit, substance abuse.

[1]. UNICEF Data: Monitoring the situation of children and women.Non-communicable diseases are critically important for adolescents now and in the future. Available from- https://data.unicef.org/topic/child-health/noncommunicable-diseases/. Accessed on 06.07.2021
[2]. WHO adolescent data. Maternal, Newborn, Child And Adolescent Health And Ageing. Available from - https://www.who.int/data/maternal-newborn-child-adolescent-ageing/adolescent-data. Accessed on 06.07.2021
[3]. Adolescent Nutrition. A Review of the Situation in Selected South-East Asian Countries WHO Regional Office for South-East Asia. 2006;8-15.
[4]. Mahmood SE, Khan KMB, Agrawal AK. Study of lifestyle disease risk factors among school going adolescents of urban Bareilly,Uttar Pradesh,India. International Journal of Community Medicine and Public Health 2017. 4(2)
[5]. WHO- Global school based student health survey (GSHS). Available from- https://www.who.int/teams/noncommunicable-diseases/surveillance/systems-tools/global-school-based-student-health-survey. Accessed on 17.2.17

Abstract: The formation and deposition of the -amyloid peptide (A) are largely thought to be responsible for the development of Alzheimer's disease (AD). Researchers have been perplexed by the sluggish to nonexistent association between the degree of clinical dementia and the amount of neuritic plaque disease in the human brain for a long time. This question has been resolved thanks to recent developments in our knowledge of the origins of amyloid disease. The solubility of A and the amount of A in various pools may now be more directly tied to disease state, according to substantial evidence. The make-up of these pools of A reflects various populations of amyloid deposits and is clearly correlated with the patient's clinical condition. Using imaging methods, such as novel amyloid......

Keywords: Amyloid, β-Amyloid Precursor Protein, Aβ, Oligomer, Fibril

[1]. Lee VM, Goedert M, Trojanowski JQ. Neurodegenerative tauopathies. Annu Rev Neurosci. 2001;24:1121–1159.
[2]. Holmes C, Boche D, Wilkinson D, Yadegarfar G, Hopkins V, Bayer A, Jones RW, Bullock R, Love S, Neal JW, Zotova E, Nicoll JA. Long-term effects of Abeta42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial. Lancet. 2008;372:216–223.
[3]. Holtzman DM. Alzheimer's disease: Moving towards a vaccine. Nature. 2008;454:418–420.
[4]. Collinge J, Clarke AR. A general model of prion strains and their pathogenicity. Science. 2007;318:930–936. [PubMed] [Google Scholar]
[5]. Aguzzi A, Sigurdson C, Heikenwaelder M. Molecular mechanisms of prion pathogenesis. Annu Rev Pathol. 2008;3:11–40

Abstract: Background: Abnormal uterine bleeding (AUB) is defined as any type of bleeding in which the amount, duration, frequency and cyclicity is abnormal for a patient.1 In order to treat the condition, it is important to identify the cause of bleeding. Treatment must remain individualised and encompass the impact of pressure symptoms, desire for retention of fertility and contraceptive needs, as well as address the management of their AUB in order to achieve improved quality of life. This study was conducted to study the various treatment modalities in AUB with a detailed analysis of medical management which may effevtively avoid surgical approach in such patients and thereby decrease morbidity and improve quality of life. Materials and Methodology: This study was conducted......

Keywords: Adenomyosis, menorrhagia, ovulatory dysfunction, uterine bleeding.

[1]. Munro MG, Critchley HO, Fraser IS. The flexible FIGO classification concept for underlying causes of abnormal uterine bleeding. InSeminars in reproductive medicine 2011 Sep (Vol. 29, No. 05, pp. 391-399). © Thieme Medical Publishers.
[2]. Munro MG, Critchley HO, Broder MS, Fraser IS, FIGO Working Group on Menstrual Disorders. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. International Journal of Gynecology & Obstetrics. 2011 Apr 1;113(1):3-13.
[3]. Matteson KA, Abed H, Wheeler TL 2nd, Sung VW, Rahn DD, Schaffer JI, et al. A systematic review comparing hysterectomy with less‑invasive treatments for abnormal uterine bleeding. Journal of Minimal Invasive Gynaecology 2012;19:13‑28.
[4]. Kjerulff KH, Erickson BA, Langenberg PW. Chronic gynecological conditions reported by US women: findings from the National Health Interview Survey, 1984 to 1992. American journal of public health. 1996 Feb;86(2):195-9.
[5]. Sinha K, Gurung P, Sinha HH, Bhadani PP. Study on abnormal uterine bleeding among adult women in a tertiary care hospital in Bihar, India. International Journal of Reproduction, Contraception, Obstetrics and Gynecology. 2018 Aug 1;7(8):3136-41.