Series-1 (March-April 2019)March-April 2019 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Antimicrobial Activities of Some Plant Extracts against Some Fungal Pathogens |
| Country | : | Saudi Arabia |
| Authors | : | Madeha N. Alseeni || Enas M. Allheani || Safaa Y. Qusti || Najlaa Y. Qusti || Sulafah A. Alotaibi || Hawazin A. Alotaibi |
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: | 10.9790/3008-1402010110  |
Abstract: One of the major clinical problems is the resistance of fungal species towards most of the used antifungal agents. The search for new antifungal drug from plants helped to overcome this problem. This study evaluated the effects of some fruits extracts cited in the Holy Quran as antifungal agents. In this study, antifungal susceptibilities assessment of water and methanolic extracts of fruits extracts were done against Aspergillus niger, Aspergillus parasiticus, Fusarium oxysporum, and Alternaria alternate by well diffusion method. Microdilution susceptibility assay was used in order to determine the minimal inhibitory concentrations (MICs) of the plant extracts. Among the evaluated plants, methanolic extract was more effective than water extract. The inhibition zone.........
Key words: Antifungal activity; Plant extract; MIC, Garlic
[1]. Adnan, M., Gul, S., Batool, S., Fatima, B., Rehman, A., Yaqoob, S., … Aziz, M. A. (2017). A review on the ethnobotany, phytochemistry, pharmacology and nutritional composition of Cucurbita pepo L. The Journal of Phytopharmacology JPHYTO, 6(62), 133–139.
[2]. Ahmad, I., Owais, M., Shahid, M., & Aqil, F. (2010). Combating Fungal Infections: Problems and Remedy. Springer Science & Business Media. https://doi.org/10.1007/978-3-642-12173-9_13
[3]. Alam, E. A. (2014). Innovare Academic Sciences Volatile Components Of Banana Peels Tea ; A New Pharmaceutical Product, 6(3), 6–7.
[4]. Arif, T., Bhosale, J. D., Kumar, N., Mandal, T. K., Bendre, R. S., Lavekar, G. S., & Dabur, R. (2009). Natural products - Antifungal agents derived from plants. Journal of Asian Natural Products Research, 11(7), 621–638.
[5]. Ateeq, A., Sunil, S. D., Varun, S. K., & Santosh, M. K. (2013). Phoenix dactylifera Linn.(PIND KHARJURA): A review. International Journal of Research in Ayurveda and Pharmacy, 4(3), 447–451.
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| Paper Type | : | Research Paper |
| Title | : | Comparative Quality Assurance Assessment of some Commercially Available Brands of Paracetamol tablets in Benin City Metropolis, Edo State, Nigeria |
| Country | : | Nigeria |
| Authors | : | Obarisiagbon Aiwaguorejohnbull || Ovile Gift || Umoru Albert || Egbunu Hauwa Kulu |
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: | 10.9790/3008-1402011117 |
Abstract: Paracetamol (acetaminophen) is a drug used to temporarily relieve mild to moderate pain associated with headaches, menstrual periods, toothaches, backaches, osteoarthritis, or cold/flu aches and to reduce fever. It is one of the most found over the counter (OTC) drugs in many households and also the most perceived frequently faked product worldwide. This study was carried out to comparatively assess the quality of paracetamol tablet brands sold in the different pharmacies, dispensaries in Benin City metropolis with reference to Pharmacopoeia standards. Materials and method: A total of 11 brands of paracetamol conventional tablets(500mg) were purchased from different locations in Benin City. Quality control parameters like organoleptic, weight variation, hardness, friability, tensile strength, disintegration........
[1]. Dipak J. kanabar (2017). A clinical and safety review of paracetamol and ibuprofen in childen. Inflammopharmocology, 25(1): 1 – 9. doi: 10.1007/s 10 787-016-030 2-3
[2]. Maurizio de Martino and Alberto Chiarug (2015). Recent Advances in Pediatric use of Oral Paracetamol in Fever and Pain Management. Pain Ther. 4(2): 149 – 168. Dio: 10. 1007/s 40122 – 015 – 0040 Z.
[3]. What dose of paracetamol for older people? (2018). Drug and Therapeutics Bulletin, 56(6): 69 – 72.
[4]. Wiffen PJ, Derry S, Moore RA,McNicol ED, Bell RF, Carr DB, Mcintyre M and Wee B (2017).Oral paracetamol (acetaminophen) for cancer pain. Cochrane Database of Systemic Reviews. Issue 7. Art No: CD012637. Doi: 10. 1002/ 14651858. CD012637. Pub2
[5]. Chow S (1997). Pharmaceutical validation and process controls in drug development. Journal of Drug Information, vol. 31, pp 1195 – 1201.
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| Paper Type | : | Research Paper |
| Title | : | Characterisation of a Bacterium Lipase (Pseudomonas Fluoresens) From Vegetable Oil Polluted Soil |
| Country | : | Nigeria |
| Authors | : | Popoola, B.M || Onilude, A.A, || Fakayode I.B |
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: | 10.9790/3008-1402011826 |
Abstract: Bacteria are very useful in protecting the environment. The lipolytic activities of physiologically diverse bacteria have great potential to degrade oil spills in the environment. There is need for extensive characterisation of the bacterium lipase for the treatment of vegetable oil-polluted sites. This work was carried out to preliminarily characterise the lipase of Pseudomonas fluoresens. Pseudomonas fluoresens was screened for lipase production using standard methods. Temperature, pH, ion concentration (NaNO3 and MgSO4), enzyme concentration, nitrogen concentration, substrate concentration, time course and agitation speed were optimised for the lipase activity as well as growth. Crude enzyme of Pseudomonas fluoresens had.......
Key words: Vegetable oil spill, Lipase production, characterisation
[1]. Arpigny, J.L and Jaeger, K. 1999. Bacteria lipolytic enzyme: Classification and properties. Biochemical Journal 343(1): 177-183.
[2]. Becker, P., Koster, D., Popov, M.N., Marboss Ian, S., Antrtanikian, G. and Markl, H. 1999. The biodegradation of olive oil and treatment of lipid rich wool, waste. Water under aerobic thermophilic condition. Water Resources. 133: 653-660.
[3]. Benjamin, S. and Pandey, A 1997. Coconut cake: A potent substitute for production of lipase by Candida rugosa in solid state fermentation. Acta Biotechnology. 17: 241-251.
[4]. Benjamin, S. and Pandey, A 1998. Candida rugosa lipases: Molecular biology and versatility in biotechnology. 14(12): 1069-1087.
[5]. Bradoo, S., Saxena, R.K., Gupta, R., 1999.Partitioning and resolution of mixture of two lipases from Bacillus stearothermophilus SB1 in aqueous two-phase system.ProcessBiochemistry.35: 57– 62..
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| Paper Type | : | Research Paper |
| Title | : | Isolation and identification of Lactobacillus plantarum KM5 from camel milk for β-galactosidase production |
| Country | : | Egypt |
| Authors | : | Khadra Al-Zahrani || Reda Allam || Reda Amasha || Samyah Jastaniah || Magda Aly |
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: | 10.9790/3008-1402012735 |
Abstract: βgalactosidase is a magic and promising enzyme, usually produced frommicroorganisms, plantsand animals for different applications like preparation of lactose-free milk for food and dairy products. It was used for hydrolysis of the glucosidic bond of lactose and produced glucose and galactose. Lactose is the main sugar which was found mainly in milk and whey. Bacteria are usually used as a source of the active enzyme. In this research,twenty lactic acid bacterial isolates were obtained from dairy product samples which were collected from Jeddah, Saudi Arabia. All the bacterial isolates were screened for the presence of β-galactosidase on MRS agar medium. Only seven bacterial isolates showed green colons on MRS (Mann, Rogosa and Sharp) agar medium containing X –gal.The amount of β-galactosidase was determined by spectrophotometer using oNPG as substrate. The highest β-galactosidase producer was the isolates KM5 and W1. Comparing the two isolates deeply, isolate KM5 was the best and.......
Key words: β-galactosidase, Lactic acid bacteria, MRS agar medium, X –gal, Lacobacillus acidophilus
[1]. Akolkar, S.K.; Sajgure, A. and Lele, S.S. (2005). Lactase Production from Lactobacillus acidophilus. World Journal of Microbiology and Biotechnology, 21 :( 6-7): 1119-1122.
[2]. Anumukonda, P. and Tadimalla, P. (2010). Optimization of bioprocess parameters for the production of β-galactosidase by employing statistical methods.International Journal of Pharma and BioSciences, 1(3): 11-17.
[3]. Assefa, E.; Beyene, F. and Santhanam, A. (2008).Isolation and characterization of inhibitory substance producing lactic acid bacteria from Ergo, Ethiopian traditional fermented milk. Livestock Research for Rural Development, 20 (3):1-6.
[4]. Banerjee G, Ray A and Hasa K N (2018). Is divalent magnesium cation the best cofactor for bacterial β-galactosidase?. J.Biosci., Vol. 43, No. 5, pp. 941–945
[5]. Bury, D.; Jelen, P. and Kaláb, M. (2001). Disruption of Lactobacillus delbrueckii ssp. bulgaricus 11842 cells for lactose hydrolysis in dairy products: a comparison of sonication, high-pressure homogenization and bead milling. In novative Food Science and Emerging Technologies., 2 :( 1): 23–29..
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| Paper Type | : | Research Paper |
| Title | : | Chitin and Chitinases, Production, Characterization and Applications |
| Country | : | Egypt |
| Authors | : | Magda M. Aly || Amna N. Sediq || Afraa M. Baghdadi || Reda H. Amasha |
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: | 10.9790/3008-1402013643 |
Abstract: Shrimp shells are used as substrates for the production of Chitinase by Actinomycetes and several species of bacteria used shrimp shells or colloidal chitin for the Chitinase production. Shrimp shell waste is used for culturing of bacteria on media for higher amounts of chitinolytic enzymes. The chitinolytic activity of bacteria of Streptomyces, Bacillus and Pseudomonas genera grown on shrimp and crab shell waste were recorded due to Chitinase production. Chitin can be biodegraded within 2 months in soils resulting in an upgrading in the numbers of soil microorganisms, a decrease of the harmful fugal flora (e.g., Fusuriurn) and preventing microbial infections of the plants which led to increases in plant production. This review aimed to clearfy the importace of chitin and chitinases in nature........
Key words: Chitin, Chitinases, enzyme, bacteria, applications
[1]. Apichaisataienchote B, Altenbuchner J, Buchenauer H (2005) Isolation and identification of Streptomyces fradiae SU-1 from Thailand and protoplast transformation with the chitinase B gene from OPC-131. Curr Microbiol, 51: 116–121.
[2]. Bhattachrya D, Nagpure A, Gupta RK (2007) Bacterial chitinase: Properties and potential. Crit Rev Biotechnol, 27: 8- 21.
[3]. Boyer JN (1994) Aerobic and anaerobic degradation and mineralization of 14C: chitin by water column and sediment inocula of the York River estuary, Virginia. Appl Environ Microbiol, 60: 174–179.
[4]. FEMS Microbiol Rev, 11: 317–338.
[5]. Chang WT, Chen M, Wang SL (2010) An antifungal chitinase produced by Bacillussubtilis using chitin waste as a carbon source. World J Microbiol Biotechnol, 26: 945–950..
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| Paper Type | : | Research Paper |
| Title | : | Impact of Malathion on Hematological Parameters of Clarius Batrachus |
| Country | : | India |
| Authors | : | R S Magar |
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: | 10.9790/3008-1402014445 |
Abstract: Indiscriminate use of pesticides has elevated the risk of contamination of environment and aquatic habitat. Considering above fact, the present investigation was carried out to study the impact of sublethal concentration of malathion exposed after 24, 48, 72 and 96 hours on RBC's and WBC's of Clarius batrachus. The blood analysis showed significant decrease in RBC's and WBC's content of treated group compared with control.
Key words: Clarius batrachus, Malathion, RBC, WBC, Blood
[1]. APHA (1976) : Standard methods for the examination of water and waste water, 20th ed. American Public Health Association, New York, USA.
[2]. Anees M.A. (1978) : Hematological abnormalities in a fresh water teleosl, Channa punctatus (Bloch) exposed to sublethal and chronic levels of three organophosphorus insecticides Int. J. Ecol. Envi. Sci. 4 : 53-60.
[3]. Benarji G. Rajendranath T. (1990) : Hematological changes induced by an organophosphorus insecticide in fresh water fish Clarius batrachus (Linnaeus). Trop. Freshwat. Biol. 2 : 197-202.
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[5]. Khattak I. U.D., Hafeez, M.A. (1996) : Effect of malathion on blood parameters of the fish Cyprinino watsoni. Pak. J. Zool. 8-143...
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| Paper Type | : | Research Paper |
| Title | : | Microbiological Analysis Of Herbal Medicines Collected From Different Areas Of Dhaka, Bangladesh |
| Country | : | Bangladesh |
| Authors | : | Md. Aftab Uddin || Masuma Mahbub Mimi || Salma Akhter |
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: | 10.9790/3008-1402014649 |
Abstract: The present study was attempted to determine the microbiological analysis of commonly available herbal medicines. In this regard, ten marketed herbal drugs from some herbal selling stores in the city of Dhaka, Bangladesh were collected and then examined microbiologically. Total aerobic count showed that most of these drugs were above the acceptable bacteriological limit. The samples contained the microbial contamination with viable bacteria and fungi upto 107 cfu/ml. Among the specific bacterial isolates, Staphylococcus spp. and Pseudomonas spp. were prevalent in all samples. Presence of Klebsiella spp. was also documented. The study of antibiogram profile revealed that Pseudomonas spp. was highly resistant against azithromycin, streptomycin and ampicillin whereas Klebsiella spp. was only resistant against ampicillin. This study was significant from the public health point of view as most of the herbal medicines were highly contaminated with potentially pathogenic bacterial flora having the drug resistant properties.
[1]. Bent et al. Commonly Used Herbal Medicines in the United States: A Review. The American Journal of Medicine. 2004; 116:478-485
[2]. Sharif MDM, Banik GR. Status and Utilization of Medicinal Plants in Rangamati of Bangladesh. Res. J. Agric. Biol. Sci. 2006.; 2(6): 268-273.
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[4]. Esimone, C.O., P.O. Olighe, U.E. Dibaa, and E.C. Ibezium. Gross microbial contamination of herbal medicinal products (HMPs) marketed in mid western Nigeria. International Jour. of Molecular Medicine and Advace Sciences. 2007; 3(2): 87-92
[5]. Chan, K. 2003 some aspects of toxic contaminants in herbal medicines, Chemosphere. 2003; 52:1361-1371.
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| Paper Type | : | Research Paper |
| Title | : | Attenuation of Cognitive Dysfunction in Pediatric Epilepsy with the Co-Administration of Piperine |
| Country | : | |
| Authors | : | Bindu Madhavi Boddupalli || Ramalingam Ramani || Bhrugun Anisetti |
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: | 10.9790/3008-1402015055 |
Abstract: Epilepsy is a common neurological disorder with spontaneous recurrent seizures triggered by abnormal electric impulse in brain cortex. It results in cognitive and learning problems along with seizures in children. Present investigation is aimed to decrease the cognitive problems in pediatric epilepsy with adjunct administration of Piperine along with Topiramate. Pentylenetetrazole induced seizures in mice was used as the experimental model. Seizure assessment was done according to the scale given by modified Racine. Cognitive function assessment was done by Morris water maze test and passive avoidance test. Results indicated the maximum protection from seizures both in topiramatetreated and in topiramate co administered piperine groups with maximum latency time to seizures..........
Keywords: Epilepsy, Topiramate, Piperine and Pentalynetetrazole
[1]. Van Rijckevorsel K. Cognitive problems related to epilepsy syndromes, especially malignant epilepsies. Seizure. 2006; 15 (4): 227–234.
[2]. Giangennaro C, Alberto V, Gianluca R, Silvia F, Gianfranca A, Francesca FO, Antonio P, Topiramate in children and asolescents with epilepsy and mental retardation: A prospective study on behavior and cognitive effects. Epilepsy & Behavior. 2008; 12(2): 253-256.
[3]. Chrysanthy I, Prenatal effects of antiepileptic drugs, Epilepsy Curr. 2010; 10(2): 42-46.
[4]. Yann M, Anne SM, Josette M, Sylviane P, Jean MP.Topiramate: Efficasy and tolerability in children according to epilepsy syndromes, Epilepsy Res. 2003; 53(3): 225-232.
[5]. Careman G, mark D, Petra B, Chrysanthy I, Therapeuyic doses of Topiramate are not toxic to the developing brain. Exp Neurol. 2004; 187 (2): 403-409..
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| Paper Type | : | Research Paper |
| Title | : | Proportion, Aetiology Of Urinary Tract Infections And Healthcare Seeking Behaviours Among Females Of Reproductive Age Attending Out-Patient Clinics In Kinango And Kwale Sub County Hospitals,Kwale County,Kenya |
| Country | : | Kenya |
| Authors | : | Kajambo Muli Rama || Mohamed Karama || Caroline Wangari Ngugi || Lawrence Ndung'u Muthami |
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: | 10.9790/3008-1402015670 |
Abstract: Background information: Urinary tract infection accounts for a major disease burden globally especially in the developing countries. Community-acquired urinary tract infections (UTIs) occur mostly in women and are commonly caused by Escherichia Coli. Objective and study design: This was a cross-sectional study carried out in Kwale and Kinango Sub-county hospitals, Kenya. This study aimed to determine the proportion and etiology of UTI and establish the factors influencing healthcare seeking behaviour of UTI patients among female attending the outpatient department for a period of twelve months(from September 2014 to September 2015)...........
[1]. Alex Boye, Peter Mate Siakwa , Johnson Nyarko Boampong, George Asumeng Koffuor,
[2]. Richard Kwabena Dadzie Ephraim1, Patrick Amoateng,Gyasi Obodai1, DennisPenu,(2012) Asymptomatic urinary tract infections in pregnant women attending antenatal clinic in Cape Coast, Ghana
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[5]. Ayansina, A. D. V., Morolari, B. M. and Ihuoma, J.A(2012), Incidence Of Resistant Enterobacteria In Urine Samples Of Some Undergraduates In A Nigerian University Department of Biological Sciences, Bowen University, P.M.B. 284, Iwo, Osun State, Nigeria
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| Paper Type | : | Research Paper |
| Title | : | Study Of Changes In Blood Parameters And Calculation Of PCT, MPV And DPW For The Platelets Of Laboratory Females And Males Of Albino Mice During Exposure To Doses Of PyrethriodPesticide (Alphacypermethrin) |
| Country | : | Iraq |
| Authors | : | Saphia .Ali Aitte || MysoonHussain.Zain |
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: | 10.9790/3008-1402017178 |
Abstract: The aim of this work to investigated the effect of pyrethriod pesticide alpha cypermethrin insecticide on the hematological parameters as the branch of physiological organs, were female and meal exposure for albino mice exposed to sub –lethal doses(2.5mg/kg bw and 4.75mg/kg bw) for a period 5 weeks to measure blood parameters. The decrease in R.B.C count from (8.57,to5.91(10⁶/mmᶟ), Hb from(11.7 to8.0%) and HCT, from (47.85to 29.91%)observed could be described shrinkage ,distraction and hemolysis of RBC.,MCV,MCH and MCHC then showed significant decrease (p≤0.05) in the males more than in the females compared with control group. And the significant increase was.........
Keywords: Albino mice, Hematological, pesticide, sub lethal effects , Differential erythrocytes
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| Paper Type | : | Research Paper |
| Title | : | Organic Farming: A Sustainable Food Production Strategy |
| Country | : | india |
| Authors | : | Dr. Sanjay Kumar Singh |
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: | 10.9790/3008-1402017982 |
Abstract: The practise of organic farming was previously widespread, particularly in India. However, modern agriculture, particularly the green revolution, changed it. In example, while applying fertilisers, traditional wisdom and indigenous knowledge were disregarded in favour of a scientific approach. The Green Revolution Technologies caused ecosystems to become polluted, natural resources to be depleted, biodiversity to be lost, diets to become less diverse, soil fertility to be lost or depleted, dependence on industrial inputs to be imbalanced or reduced, production to become less productive, farmers' economic returns to be reduced, pesticide use to rise, unscientific water management and distribution to be used, and produce quality to decline. All of these issues with the green revolution resulted in a decrease in output as well as a deterioration of the ecosystem and soil health.......
Keywords: Agriculture, food production, organic farming, and green revolution technology
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[3]. APEDA, National Programme for Organic Production (NPOP). (2010). Present status in India; www.apeda.com/organic.htm.
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