Abstract: The aim of the study was to evaluate the effects of date pits powder on body and fat weights, lipid profile, glucose, insulin, leptin hormones, liver enzymes, renal tissue antioxidant enzymes and histopathology of kidneys in obese diabetic rats. Forty five male Albino rats were randomized into 5 equal groups (n=9). Group A (negative control rats) was fed on basal diet, while the other 4 groups were fed on high-fat diet (HFD) for 4 weeks to induce acute obesity and hyperlipidemia. The obese rats were then rendered diabetic by intraperitoneal injection of alloxan (120 mg/kg/day) for 5 days. On becoming diabetic, group B was kept obese diabetic as positive control and while groups C, D and E were fed on basal diet containing 5%, 7.5% and 10% date pits powder respectively replaced.....
Keyword: date pits powder, anti-diabetic, anti-obesity, lipid profile, glucose, insulin, leptin hormones, liver enzymes, renal tissue antioxidant.
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