iosr-JPBS   Volume-16 ~ Issue-4 ~ Jul.-Aug. 2021

Abstract: The intent of the present study was to investigate the effect of Ulmus fulva extract in inflammatory bowel diseased rats. About 30 wistar rats were divided into 5 groups (n=6). After 48hr overnight fasting, under light anaesthesia (Phenobarbitone) colitis was induced by intera-colonic administration 1ml of 4% acetic acid to all group except the normal group. All the animals were treated as per treatment protocol. Animals treated with Ulmus fulva extract produced a significant (P<0.05) improvement in both morphological and histophological score as compared to nearer to control group. There was also a dose dependent reduction in serum Lactate dehydrogenase LDH level (P<0.001) in the test group as compared to diseased induced group. Ulmus fulva is effective in the treatment of Inflammatory Bowel Disease may be due to the development of a defensive mucosal layer.

Key Words: Inflammatory bowel disease, Ulmus fulva, LDH level, Nitric oxide and sulphasalazine.

Abstract: Contexte : Serratia marcescens est considérée comme un pathogène opportuniste, elle touche le personnel hospitalier ou les patients. Cette espèce fait partie des entérobactéries qui présentent une résistance aux agents antibactériens. Aujourd'hui, l'hôpital soigne des malades de plus en plus fragiles, exécute des actes chirurgicaux de plus en plus hardis et utilise des techniques des soins de plus en plus lourdes et invasives qui sont autant des portes d'entrée à l'infection. Cette étude se veut déterminer la proportion de souches de Serratia marcescens impliquées dans les infections nosocomiales, ainsi le taux de résistance par rapport aux antibiotiques les plus utilisés dans notre milieu........

Key Word: Nosocomial diseases ; Serratia marcescens ; incidence ; resistance to antibiotics ; Ngaliema.Clinic

Abstract: Background: Obesity is an increasing, global public health issue. Patients with obesity are at major risk for developing a range of comorbid conditions, including cardiovascular disease (CVD), which may significantly affect their daily lives as well as increased mortality risks. Cardiovascular disease (CVD) mortality and morbidity have been shown to be elevated in individuals who are overweight, particularly with central deposition of adipose tissues. Abdominal obesity has been shown to be a risk factor for CVD worldwide. Materials and Methods: A total of 300 patients attending cardiology department were subjected to prospective study for a period of 3 months in Warangal region........

Key Word: Obesity, Cardiovascular diseases, sedentary lifestyle

Abstract: Aim:- The study was carried out to assess the safety and efficacy of Majoon Aqrab and Sharbat-e-Aalu Balu in patients with ureteric stones. Material & Methods:- Study was conducted on 10 Patients having ureteric calculi less than 10 mm in size confirmed by symptomatology of the patients, Urine (R & M), ultrasound (whole abdomen), and X-ray KUB. Patients were given Majoon Aqrab and Sharbat-e-Aalu Balu for 3 months and after completion of treatment, investigations were repeated to evaluate the site, size and expulsion of stones. Results:- We found that more than 8 mm stones were expelled out completely after treatment but stone of more than 8 mm are very difficult to expelled out. Conclusion:- It was concluded that Majoon Aqrab and Sharbat-e-Aalu Balu are effective in the expulsion of small ureteric stones (less than 8 mm in size).

Key Word: Ureteric Stone, Majoon Aqrab, KUB, Sharbat-e-Aalu Balu

Abstract: In respect with increasing pollution and subsequent algal growth in River waters, study on algal flora of Kano River was conducted between October 2014 and September 2015 based on anthropogenic activities. Five stations were selected during the process sampled and examined for water physico-chemistry and phytoplankton community structure using basic statistical measurement of diversity indices to characterize the flora of the River. Parameters were examined using established procedure. The results obtained were in the following ranges: conductivity (93.57±61.28±22.10), pH (7.29±0.77-6.96±0.26), Temperature (25.83±4.36-24.53±4.23), Transparency (142.08±77.31-52.11±8.40), DO (6.57±2.75-4.67±2.03), BOD5 (3.30±1.962.16±1.59), Nitrate (2.80±1.64-1.61±1.23) and Phosphate (2.74±1.59-1.85±1.37). A total of 49 species of Phytoplankton characteristics of water samples from the River revealed varying levels of pollutions. The algae identified at the sites selected belong to the following.....

Key Word: Phytoplankton, Physicochemical Parameters, Water Quality, Seasonal Variation, Kano River

Abstract: In this paper, we studied the effect of Mn-Zn-Fe2O4/Se nanocomposite which was synthesized by coprecipitation method and investigated its therapeutic effect that induced by an alternating magnetic field on xenograft liver cancer in mice. Mn-Zn-Fe2O4/Se was described by X - ray diffraction (XRD), transmission electron microscopy (TEM) and Fourier transform infrared spectroscopy (FTIR). We also studied cytotoxicity of Mn-Zn-Fe2O4/Se nanocomposite on the HepG2 cell line. The cytotoxicity results revealed high toxicity against HepG2 cells for higher concentrations (>250 μg/mL) of Mn-Zn-Fe2O4/Se but were found to be non-toxic at lower concentrations. Reverse transcription polymerase chain reaction (RT-PCR) was used to evaluate gene expression of caspase 3, Bcl-2 and p53. The results were showed that the expression level of P53 and Casp3 was clearly up-regulated, while the expression level of Bcl-2 was down-regulated (P<0.05) after hyperthermia in treated groups.

Key Word: Mn-Zn-Fe2O4/Se nanocomposite; cytotoxicity; RT-PCR.