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| Paper Type | : | Research Paper |
| Title | : | Investigation into the aphrodisiac properties of aqueous and ethanol root extracts of Manniophyton fulvum in male Wistar rats |
| Country | : | Nigeria |
| Authors | : | Emudainohwo J.O.T. || Ejebe, D.E. || Erhirhie, E.O. || Moke E.G. |
Abstract: Manniophyton fulvum root is a popular herb amongst traditional medicine practitioners in Nigeria for the enhancement of male sexual behavior. This study therefore investigated the aphrodisiac property of aqueous and ethanol root extracts of Manniophyton fulvum by observing the sexual behavior of male Wistar rats against a standard aphrodisiac drug (Sildenafil citrate, 25 mg/kg). The mount frequency, mount latency, ejaculation latency and post-ejaculation latency were observed in animals to evaluate their sexual activity.
[1]. NIH Consensus Development Panel on Impotence. NIH Consensus Conference. Impotence. Journal American Medical Association. 270: 1993, 83-90.
[2]. M. Monga, The aging penis: erectile dysfunction. geriatric nephrology urology., 9(1), 1999, 27-37.
[3]. National Institutes of Health (NIH). Erectile Dysfunction. The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) 2004. Mar 9, (Eds: Melman A, Hirsch M. NIH Publication, December 2003; No. 04-3923. http://kidney.niddk.nih.gov/kudiseases/pubs/impotence/index.htm).
[4]. LI. Lipschultz, and E.D. Kim, Treatment of erectile dysfunction in men with diabetes, Journal American Medical Association, 281(5), 1999, 465-466.
[5]. Food and Drug Administration (FDA). Announces Revisions to Labels for Cialis, Levitra and Viagra". 2007. Retrieved on 08-06-2015 from http://www.fda.gov/bbs/topics/NEWS/2007/NEW01730.html.
[6]. WC. Evans, Trease and Evans Pharmacognosy. (15thed.). 2002. London: W. b. Saunders.
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| Paper Type | : | Research Paper |
| Title | : | Optimization of Growth Factors of Hexa Valent Chromium Reducing Bacterial Strain. |
| Country | : | India |
| Authors | : | Nagendram.K || Prof. Z. Vishnuvardhan || V.V. Ravindra |
Abstract: The aim of this work is to optimize the growth parameters for the reduction of Hexavalent Cr using isolated soil bacteria (SS 31). Different growth conditions like the nitrogen sources, pH, incubation time, temperature, agitation rate and the effect of different additional supplements was studied. The isolated strain shows more than 50% reduction on most of the conditions. But high reduction activity was found to be 0.2g/L Beef extract as nitrogen source in the broth at pH 7, incubation period of 24H at 35OC with agitation rate of 50rpm. The presences of additional supplements like Cystine amino acid, EDTA as metabolic inhibiter, Thiamine vitamin and Streptomycin antibiotic in the culture broth was found enhance the Cr reduction activity. All the optimization studies were studied at Cr concentration of 100μg/ml.
Key Words: Bioremediation, Soil bacteria, Cr Reduction, Optimization of growth parameters
[1]. Sarkar B. (ed.). Heavy Metal in the Environment, (ed.) Marcel Dekker, Basel, Switzerland. pp. 271-309
[2]. Ahluwalia SS, Goyal D. Microbial and plant derived biomass for removal of heavy metals from wastewater. Bioresource Technology. 2007; 98(12):2243–2257
[3]. Adriano DC. Trace Elements in Terrestrial Environments: Biogeochemistry, Bioavailability, and Risks of Metals. Springer, 2001, 316–348.
[4]. Das S, Chandra AL., Chromate reduction in Streptomyces., Experientia., 1990, 46: 731-733.
[5]. Nagendram Kattepogu, Prof. Z. Vishnuvardhan, V.V. Ravindra, isolation and screening chromium reducing Bacteria from industrial effluents and Polluted soil, The Experiment, 2015., 33(2), 2090-2095.
[6]. Massaccesi G, Romero MC, Cazau MC, Bucsinszky AM. Cadmium removal capacities of filamentous soil fungi isolated from industrially polluted sediments, in La Plata (Argentina) World Journal of Microbiology and Biotechnology. 2002; 18(9):817–820.
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| Paper Type | : | Research Paper |
| Title | : | Assessment of Healthcare Professional Awareness towards Haemovigilance (HvPI) Programme of India in South India |
| Country | : | India |
| Authors | : | Narmada Sireesha. V || Pavan Kumar Reddy. G.V || Jollireddy Sravani || Dr. Shoba Rani. R. H || Dr. Mohanraj Rathinavelu |
Abstract: Haemovigilance concerns the follow-up of whole blood and labile blood components for transfusion: red cell concentrates, platelets and plasma (fresh frozen plasma, FFP). The major requirement of any transfusion medicine is 'zero risk' to the recipient, as the aftermaths of any error during transfusion is huge. The proposed prospective observational study of six month duration was performed in a tertiary care teaching hospital of Andhra Pradesh aimed in evaluation and to explore the awareness among healthcare professionals towards Haemovigilance Programme of India (HvPI), which included 83 healthcare professionals, provided with an validated questionnaire designed with an extensive literature survey and expertise suggestion.
[1] R. R. P. de Vries, J.-C. Faber, P. F. W. Strengers, Muhammad Amir, Haemovigilance: an effective tool for improving transfusion practice; Vox Sanguinis 2010 International Society of Blood Transfusion, Vox Sanguinis (2011) 100, 60–67. [2]. Bernard J: La legende du Sang. Paris, Ed. Flammarion, 1992. [3]. Schmidt PJ, Leacock AG: Forgotten transfusion history: John Leacock of Barbados. BMJ 2002; 325(7378): 1485–1487. [4]. Noel L, Debeir J, Cosson A: The French haemovigilance system. Vox Sang 1998; 74(Suppl 2):441–445. [5]. Andreu G, Morel P, Forestier F, et al.: Hemovigilance network in France: organization and analysis of immediate transfusion incident reports from 1994 to 1998. Transfusion 2002. [6]. ihm-org.com [about/definition-of-haemovigilance] International Haemovigilance Network. [Cited: 5/2/2014]. Available from: http://www.ihn-org.com/about/definition-ofhaemovigilance/42(10):1356–1364. [7]. Engel Brecht S, Wood EM, Cole-Sinclair MF, "Clinical transfusion practice update: haemovigilance, complications, patient blood management and national standards.‟ PMID: 24033212 [PubMed - indexed for MEDLINE].
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| Paper Type | : | Research Paper |
| Title | : | In vitro Ovicidal Activity of Encapsulated Ethanolic Extract of Prosopis juliflora Against Haemonchus contortus Eggs |
| Country | : | Kenya |
| Authors | : | Cheruiyot Kipyegon || Kutima L. Helen || Kareru G. Patrick || Njonge K. Francis || Rechab S. Odhiambo || Mutembei K. Jackson || Madivoli Edwin |
Abstract: Haemonchus contortus is one of the most prevalent and highly pathogenic nematode parasites of small ruminants. Development of resistance and degradation of active compounds of conventional anthelmintic drugs prompted evaluation of encapsulated medicinal plant extracts as alternative anthelmintics. The in vitro ovicidal activity of encapsulated extract of Prosopis juliflora was determined using Egg hatch inhibition assay on H.contortus eggs. The tests were evaluated at six concentrations (0.63, 0.13, 0.25, 0.5, 1.0 and 2.0 mg/ml) and in drug to polymer ratios of (1:2, 1:1 and 2:1).
[1]. Akhtar, M. S., Kabal, Z., Khan, M. N. and Lateef, M. (2000). Anthelmintic activity of medicinal plants with particular reference to their use in animals in Indo-Pakistan sub-continent. 38: 99-107. Small Ruminant Research , 38: 99-107.
[2]. Bachaya, H., Iqbal, Z., Jabbar, A. and Ali, R. (2006). Copping with loss of livestock. Retrieved from http://www.dawn.com/2006/02/26/eber5.htm.
[3]. Barger, I. and Cox, H. W. (1984). Wool production of sheep chronically infected with Haemonchus contortus. Veterinary Parasitology , 15: 169-175.
[4]. Coles, G. C., Geerts, S., Klei, T. R., Tailor, M. A. and Waller, P. J. (1992). World association for advancement in veterinary parasitology (WAAVP) methods for the detection of anthelmintic resistance in nematodes of veterinary importance . Veterinary Parasitolology , 44: 35–43.
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| Paper Type | : | Research Paper |
| Title | : | Phytochemical Constituents and Toxicological Study of Vitex Doniana Leaf |
| Country | : | Nigeria |
| Authors | : | Dawang N. D |
Abstract: The continuous emergence of multidrug resistance by microorganisms to antibiotics has lead to increased use of medicinal plants. Therefore it is needful to ascertain the presence of thephytochemical constituents and toxicity of Vitex doniana leaf. The phytochemical screening was performed using standard qualitative procedure. The acute toxicity effect of ethyl acetate Vitex doniana leaf extract was determined by Lorke's method. The experiments involved oral administration of different doses of the plant extract on mice per body weight. The leaf extract of V. doniana contained alkaloids, flavonoids, cardiac glycosides, terpenes, steroids and resins.
[1]. Prajapati B,Rai GK,Rai SK,Upreti HC,Thapa M,Singh G and Shretha RM (2008).Prevalence of Salmonella Typhi and Paratyphi infection in children:a hospital based study. Nepal Medical Journal, 104(4):238-241.
[2]. Harley RM, Atkins S, Budantsev A, Cantino PD, Conn, BJ, Grayer RJ, Harley,MM, de Kok, RP, KrestovskajaTV,Morales R, Paton AJ and Ryding PO. "Labiatae" The families and Genera of Vascular Plants, Vol.V11. Springer-Verlag:Berlin, Heidelberg, Germany,2004; 167-275
[3]. Dauda, BEN, Oyeleke SB, Jigam AA, Salihu, SO and Balogun, MM Phytochemical and In-vitro antibacterial investigation of Vitex doniana leaves stem Bark and Root bark Extracts. Australian Journal of Basic and Applied Science ,2011;5(7):523-528.
[4]. Irvine FI.Woody plants of Ghana with special reference to their uses. Oxford University Press, London, 1961; pp868
[5]. Etta EN Preliminary investigation into the anti-diarrheal activity of extracts of the leaves of Vitex doniana Sweet. B. Pharm.Thesis, Pharmacology, University of Nigeria, Nsukka, Nigeria, 1984
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| Paper Type | : | Research Paper |
| Title | : | Study of the cytotoxic effect of new transition metals complexes: Cobalt (II) and Cadmium (II) on cancer cell line (Hep2) comparison with two anticancer drugs |
| Country | : | Iraq |
| Authors | : | Jinan Hussein Murtadha || Iman Hashim Abdul Razzaq || Mahasin Faisal Alias |
Abstract: The present study involved the cytotoxic effect of cobalt complex with formula [CoL(H2O)NO3]. 4ETOH where L= Nitro [5-(P-nitro phenyl)-4-phenyl-1,2,4-traizole -3- dithiocarbamato hydrazide] aqua cobalt (II). Ethanol (4) and cadmium complex with formula [CdL2]. 1/2 H2O where L= Bis [5-(P-nitro phenyl) – 4- phenyl -1,2,4- traizole -3- dithiocarbamato hydrazide] cadmium (II) hydrate (0.5) on the growth of heaptocellulare carcinoma (Hep2) cell line by using in vitro system comparison with two anticancer drugs (Cyclophosphamide and Cisplatin ) as appositive control..
[1]. Shazia, R., Muhammed, I., Anwar, N., Haji, A and Amin, A. 2010. Transiton metal complexes as potential therapeutic agents. Biotechnology and molecular Biology Reviews. Vol. 5(2), PP.38-45.
[2]. Hartwig, A., Asmuss, M., Ehleben, I., Herzer, u., Kostelac, D., Pelzer, S. and Burkle, A. 2002. Interference by toxic metal ions with DNA repair processes and cell cycle control: molecular mechanisms, 110(5): 797 – 799.
[3]. Shriver, F., Atkins, P.w., Overtone, T.L., Rouke, J.P., Weller, M.I and Arrmstone, F.A. 2006.
[4]. Pan jehpour , M. and Bayesteh , M. 2008 . The cytotoxic effects of Cadmium chloride on the human lung carcinoma ( Calu -6) cell line , Res . Pharm . Sci.3(2) : 49 -53 .
[5]. Okwuosa, C.N., Achukwu, P.V. and Aboh, A. 2012. Protective effect of the leaf exracts of combretum racemosum, P. Beauv (combretacea on cyclophophamide induced pancytopaenia and liver injury in made rats research, J. pharm. 6(2): 30-34.
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| Paper Type | : | Research Paper |
| Title | : | Status And Risk Factors Associated With Infantile Geohelminths Infections In Sokoto State, Nigeria. |
| Country | : | Nigeria |
| Authors | : | Isyaku, N.T || Nock, I.H || Ndams, I.S || Luka, S.A |
Abstract: A study on geohelminths infections among infants in Sokoto State was conducted in nine Local Government Areas between the months of August, 2013 to December, 2014 in order to evaluate the status of infantile geohelminthiasis and the associated risk factors in Sokoto State. Stool samples obtained from 1620 infants aged 1 to 24 months were screened using the formol- ether concentration techniques. An overall low prevalence of 1.4% was obtained in the State. Hookworm has the highest prevalence of 17(1.0%), followed by S. stercoralis with an overall prevalence of 4(0.2%).
[1]. Abdullahi, I. O. and Abdulazez, A. J. (2000). Prevalence of intestinal parasites in some human patients in Zaria. The Nigerian Journal of Parasitology, 21: 25-30.
[2]. Adamu, T., Abubakar, U., Lawal, M. and Aliyu, B. A. (2006). Intestinal Helminth Parasites Among School Children in Wamakko Local Government Area of Sokoto State, Nigeria. The Zoologist, 3:34-39.
[3]. Adebote, D.A., Balarebe, M.L, .Kogi, E., Oniye, S.J. and Olorunsola, G.O. (2004). Preliminary observation on helminth infections in pre-school children in three villages in Zaria. Nigerian Journal of Tropical Biosciences, 4:83-88.
[4]. Alemu, A., Atnafu, A., Addis, Z., Shiferaw Y. and Teklu, T. (2012). Soil transmitted helminths and schistosoma mansoni infections among school children in Zarima town, northwest Ethiopia. Parasitology International, 61: 101–106.
[5]. Allen, A.V. and Ridley,D.S.(1970). Further observations on the formol-ether concentration techniques for faecal parasites. Journal of Clinical Pathology, 23:545-546.
[6]. Arcari, M., Baxendine, A. and Bennett, C.E. (2000). Diagnosing Medical Parasites through Coprological Techniques. www.soton, Ac. Uk/ceb/Diagnosis/vol 1. htm.
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| Paper Type | : | Research Paper |
| Title | : | Analysis of Water Quality by Physico-Chemical Parameters in Fateh Sagar Talab in Bagar, Dist. of Jhunjhunu (Raj.), India |
| Country | : | India |
| Authors | : | Sunita Verma || J.B. Khan |
Abstract: This Paper Present to study of the Physico-chemical Parameters of Fateh Sagar Talab in Bagar of Jhunjhunu district in Rajasthan. The study was carried out for a period of one year i.e. July 2012 to June 2013. Water samples were collected monthly from surface water and analyzed for Temp, pH, electric conductivity, total hardness, Alkalinity, TDS (Total dissolved solid), chloride, DO (Dissolved oxygen). This study was aimed to estimate current status of Physico-chemical chararacterstics.
Keywords: Water sample, physico-chemical parameters, pollution, aquatic organisms.
[1] A. U. Uduma and M.B. Uduma, Physico-chemical analysis of the quality of Sachet water consumed in Kano metropolis. Americal Journal of Environmnt Energy and Power Res, (2)1, 2014, 01-10.
[2] S. Abdullah, M.A. Iqbal, M.I. Fazil, Physico-chemical Analysis of the Fresh Water at Kundalika Dam, Upli Dist. Beed, (M.S.) India. Global Journal of Environmental Research, 4 (1), 2010. 01-05.
[3] M.M. Bhat, K. Narain, A. Ahmad, R.N. Shukla and M. Yunus, Seasonal Variations of Physico-chemical Characteristics in several Ponds of Lucknow city affected by Urban Drainage. Advanced in Envronmental Biology, 6(10), 2012, 2654-2663.
[4] G.E. Hutchinson, A treatise on limnology Vol. I & II Geography, Physics and Chemistry. John Willey Inc. New York, 1957.
[5] B.K. Dwivedi and G.C. Pandey, Physico-chemical factors and algal diversity of two ponds, (Girija Kund and Maqubara pond), Faizabad. Poll. R.S. 21, 2002, 361-370. [6] V. Kannan and S.V. Job, Diurnal depth-wise and seasonal changes of physico-chemical factors in Sathiar reservoir. Hydrobiologia, (70)1-2, 1979, 103-117.
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| Paper Type | : | Research Paper |
| Title | : | Biochemical Evaluation of the Metabolic Abnormalities Associating with Hepatitis C virus Patients |
| Country | : | Egypt |
| Authors | : | E. El Agroudy || Omnia .E. STEAT || Mostafa .A. Hussien || Nahla.H.Anber || Shereen .M. Attallah |
Abstract: Hepatitis C virus (HCV) is one of the main causes of liver disease worldwide, with more than 150 million of persons chronically infected, at risk of developing liver cirrhosis and cancer. Moreover, HCV infection is associated with glucose and lipid metabolism disturbances. HCV can induce insulin resistance through several mechanisms. Indeed, the virus interferes with insulin signaling both directly and indirectly, inducing the production of pro-inflammatory cytokines. In this study, we assess the metabolic abnormalities in patients with chronic hepatitis C virus infection, in order to estimate the potential link between HCV patients and metabolic syndrome. The study included 65 subjects, 55 HCV patients&10 healthy individuals with matched age &sex. Determination of oral glucose tolerance test (OGTT), liver enzymes, lipid profile and serum insulin were done for all subjects. Total cholesterol, triglycerides and LDL levels were lower in HCV with DM when compared to control group (statistically significant difference p<0.001).
[1]. Narita R, Abe S and Kihara Y (2004): Insulin resistance and insulin secretion in chronic hepatitis C virus infection. J Hepatol, 41: 132-138.
[2]. Petit JM, Bour JB and Galland-Jos C (2001): Risk factors for diabetes mellitus and early insulin resistance in chronic hepatitis C. J Hepatol; 35: 279-283.
[3]. Okuda M, Gosert R, Xiao SY, Weinman SA and Lemon SM (2002):Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus. Gastroenterology, 122, 352
[4]. Adinolfi LE, Durante-Mangoni E and Zampino R (2005):Review article: hepatitis C virus-associates steatosis – pathogenic mechanisms and clinical implications. Aliment PharmacolTher, 22(suppl2): 52-55. [5]. Agnello V, Abel G, Elfahal M, Knight GB, Zhang QX. Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. ProcNatlAcadSci U S A. 1999; 96(22):12766–12771.
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| Paper Type | : | Research Paper |
| Title | : | Effect of Alpha-Glucosidase Inhibitory Property and Glucose Uptake Assay In L6 Cell Line ByGriffithsia Pacifica Kylin |
| Country | : | India |
| Authors | : | R. Lalitha || S. Palani |
Abstract: The whole red algae Griffithsia Pacifica Kylin (GPK) has not yet been known for its in vitro anti-diabetic property. This research was performed to investigate the ability of GPK fractions as an anti-diabetic agent. On the first stage extraction of GPK was performed using ethanol. On the second stage in vitro anti-diabetic activity was performed using α-glucosidase enzyme and determination of cytotoxic properties of GPK in selected L6 cell line of rat skeletal muscles.In brief, the 24 hr. cell cultures with 70-80% confluences in 40mm petri plates were allowed to differentiate by maintaining in DMEM with 2% FBS for 4-6 days. The extent of differentiation was established by observing multinucleation of cells.
[1]. Abid M, Khan NA, Krishna A, Yadav MK, KishoreK, Ghosh AK. Prescription pattern of Drug andDiseases Related to diabetes mellitus. Journal ofAdvanced Pharmaceutical Research 2010; 1(2), 140-145.
[2]. Bhagwat DA, Killedar SG, Adnaik RS. Anti-diabeticactivity of leaf extract of Tridaxprocumbens.International journal of green pharmacy 2008.
[3]. Riaz S. Diabetes mellitus. Scientific Research andEssay 2009; Vol. 4 (5) pp. 367-373, Academicjournals.
[4]. Bastaki S. Diabetes mellitus and its treatment.International journal of diabetes and metabolism2005; 13:111-134.
[5]. 5.Maritim AC, Sanders RA, Watkins JB. Diabetes, oxidative stress, and antioxidants: a review. J Biochem Mol Toxicol 2003;17(1):24-38.