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| Paper Type | : | Research Paper |
| Title | : | A Review on Plectranthus vettiveroides: An Endemic to South Indian High Value Aromatic Medicinal Plant |
| Country | : | India |
| Authors | : | B. A. Nisheeda || P. M. Safeer || S. Sreekumar || C. K. Biju || G. Seeja || C. Manivannan |
Abstract: Plectranthus vettiveroides (K. C. Jacob) N. P. Singh & B. D. Sharma is an endemic to South Indian aromatic medicinal plant which is at present extinct in the wild and cultivated only in Kollidam in Cuddallore district, Tamil Nadu by few farmers as part of fulfilling their religious customs and belief. It's root extract has been used as a single or an ingredient in more than 75 herbal drugs which are marketed by leading manufactures in all over the world. But when commensurate with its production it is obvious that the drug manufactures are using substitute or adulterants......
Keywords: Agrotechnology, Coleus, Essential Oil, Herbal Drug, Iruveli, Plectranthus vettiveroides
[1]. K. Cherian Jacob, A new species of Coleus, Journal of Bombay Natural Historical Society, 42, 1941, 320-322.
[2]. P. K. Warrier, V. P .K. Nambiar, and C. Ramankutty, Indian medicinal plants: A compendium of 500 species Vol. 4, (Orient Longman1995), 978-81.
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[4]. H. Soni, and Akhlesh Kumar Singhai, Recent updates on the genus Coleus: A review, Asian Journal of Pharmceutical and Clinical Research, 5, 2012, 12-17.
[5]. B. Mamatha, and T. N. Shivananda, Influence of different growth media to promote plant and root growth of Coleus vettiveroides, Crop Research, 43 (1, 2 & 3), 2012,128-130.
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| Paper Type | : | Research Paper |
| Title | : | Anti-Diabetic Effect of Occimum Gratissimum on Blood Glucose Level in Alloxan Induced Diabetic Rats |
| Country | : | Nigeria |
| Authors | : | Ekaiko, M.U || Ndulaka J.C || Ogbonna C.R || Asiegbu E.I |
Abstract: In The Present Study, The Anti Diabetic Effect Of Occimum Gratissimum On Alloxan Induced Diabetic Rats Was Investigated Using Standard Methods. The Result Revealed That The Blood Glucose Levels Of The Rats Were Reduced Following Treatment With The Aqueous Extract Of Occimum Gratissimum. From The Result, At 400mg/Kg, The Blood Glucose Level Reduced Down To 50.0±3.16mg/..........
Keyword : Anti-Diabetes, Occimum Gratissimum, Alloxan, Diabetes, Blood Glucose Level.
[1]. M. Chukwuma. Bitter leaf, Scent leaf extract protects Diabetics from Heart, Testicular Damage. Guardian. 19 July, 2012.
[2]. J.B. Calixto, Efficacy, safety, quality control marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents) Braz. J. Med. Biol. Res.33: 2000 179-189.
[3]. J. E. Ehiagbonare, Macropropagation of Ocimum gratissimum L: A multi purpose medicinal plant in Nigeria. African Journal of Biotechnology Vol. 6 (1), 2004 pp. 013-014.
[4]. S. Y Giami, Achinewhu S.C and Ibaakee .C, The quality and sensory attributes of cookies supplemented with basil (Ocimum gratissimum) in J. Food Sci. Technol., 40: 2005,613-620.
[5]. T. Essawi, M. Srour, Screening of some Palestinian medicinal plants for antibacterial activity. Journal of Ethnopharmacology 70, 2000; 343-349.
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| Paper Type | : | Review Paper |
| Title | : | Continuing Aspirin Therapy Does Not Increased Risk Of Bleeding For Patients Undergoing Minor Dental Procedures |
| Country | : | |
| Authors | : | Azzaldeen Abdulgani || Omar Sadeq || Jabareen Ali || Ziyad Kamal Mohammad || Kontoes Nikos || Thomy Kouremada || Georges Chlorokostas || Muhamad Abu-Hussein |
Abstract: Aspirin is a common, chronically administered preventive treatment for cardiovascular disease . It has been used traditionally as analgesic and anti- inflammatory for centuries and is one of the world's most widely used drug. Aspirin or acetyl salicylic acid is still the only non steroidal anti-inflammatory drug used in the treatment and prevention of thromboembolic diseases.....
Keywords: Aspirin, Dental Extraction, Bleeding, Thromboembolism
[1]. Jafri SM, Zarowitz B, Goldstein S, Lesch M. The role of antiplatelet therapy in acute coronary syndromes and for secondary prevention following a myocardial infarction. Prog Cardiovasc Dis 1993;36:75-83.
[2]. Owens CD, Belkin M. Thrombosis and coagulation: Operative management of the anticoagulated patient. Surg Clin North Am 2005;85:1179-89, x.
[3]. Shah M, Dave D, Dave R, Bharwani A, Shah A. Management of medically compromised patient in periodontal practice: An overview (Part 1). Adv Hum Biol 2013;3:1-6.
[4]. Cañigral A, Silvestre FJ, Cañigral G, Alós M, Garcia-Herraiz A, Plaza A. Evaluation of bleeding risk and measurement methods in dental patients. Med Oral Patol Oral Cir Bucal 2010;15:e863-8.
[5]. Dogne JM, de Leval X, Benoit P, Delarge J, Masereel B, David JL. Recent advances in antiplatelet agents. Curr Med Chem2002;9:577-89.
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| Paper Type | : | Review Paper |
| Title | : | Phytochemical Screening And Antibacterial Activity Of Yemeni Henna (Lawsonia Inermis) Against Some Bacterial Pathogens |
| Country | : | Nigeria |
| Authors | : | Khaled S. Ali || Fuad A. Al-hood || Khaldoon Obad || Mohammed Alshakka |
Abstract: The presence of trypanosome parasites in ixodidae ticks of cattle naturally infected with trypanosomiasis in semi-extensively managed herd of white Fulani cattle was studied. The ticks were naturally attached to the cattle. Each of the cattle harbours about 120 ticks with one tick marked for this study on each of the following regions; sternal region, peri-anal region and under the tail......
Keywords: Amblyomma variegatum, Ixodidae, peri-anal, sternal and trypanosomiasis,
[1]. Stevens JR, Brisse S (2004). Systematics of trypanosomes of medical and veterinary importance. In: The trypanosomiases (Eds. 1. Maudlin, P. H. Holmes and M. A. Miles), CABI publishing, Cambridge, USA, pp. 1-24.
[2]. Ormerod WE (1970). Pathogenesis and pathology of trypanosomiasis in man. In. The African trypanosomiases (Ed. H.W. Mulligan). George Allen and Unwin, pp 587-607.
[3]. Animal Disease Factsheets. (2005). The Center for Food Security and Public Health Iowa State University, Ames, IA, USA. Retrieved from http://www.cfsph.iastate.edu.
[4]. Oluwafemi RA, Ilemobade AA, Laseinde EAO (2007). The Impact of African Animal trypanosomosis and tsetse on the livelihood and well being of cattle and their owners in the BICOT study area of Nigeria. Sci. Res. Essay 2(9): 380-383.
[5]. Leach TM (1973). African trypanosomiasis. Adv. Vet. Sci. Comp. Med. 17: 119 - 162.
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| Paper Type | : | Review Paper |
| Title | : | Phytochemical Screening and in-vitro Anti-Inflammatory Activity of Methanolic Extract of Sterculia foetida L. |
| Country | : | India |
| Authors | : | Rubina NS || Mubeen MA || Kiran N || Vijay P || Asmabutool S || Imaduddin MD |
Abstract: Sterculia foetida (S. foetida) is a tall tree located in India, Malaysiaand North East Australia. Decoction of bark in folklore medicine was used for the treatment of dropsy and rheumatism. The main focus of this work was to evaluate in-vitro anti-inflammatory activity of methanolic extract of sterculia foetida (MESF) bark using Human Red Blood Cell(HRBC) membrane stabilization technique. In this study Diclofenac sodium was used as standard drug at a conc......
Keywords: Anti-inflammatory,HRBC membrane, Membrane stabilization,S. foetida.
[1]. L. Ferrero-Miliani, O.H. Nielsen, P.S. Andersen, S.E. Girardin, Chronic inflammation: importance of NOD2 and NALP3 in
interleukin-1beta generation, Clin. Exp. Immunol, 147 (2), 2007, 227-235.
[2]. A.B. Abbas, A.H. Lichtman, "Ch.2 Innate Immunity". In Saunders. Basic Immunology. Functions and disorders of the immune
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[3]. "Handout on Health: Rheumatoid Arthritis". National Institute of Arthritis and Musculoskeletal and Skin Diseases. August 2014.
Retrieved July 2, 2015.
[4]. R. Lozano, M. Naghavi, K. Foreman, S. Lim, K. Shibuya, V. Aboyans, J. Abraham, T. Adair, "Global and regional mortality from
235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010",
Lancet, 380 (9859), 2012, 2095–128.
[5]. Y. Alamanos, P.V. Voulgari, A.A. Drosos, Voulgari, Drosos, "Incidence and prevalence of rheumatoid arthritis, based on the 1987
American College of Rheumatology criteria: a systematic review", Semin. Arthritis Rheum, 36 (3), 2006, 182–188.
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| Paper Type | : | Review Paper |
| Title | : | Validation of Russell's Viper Venom Detoxification Activity of Azadirachta indica through In Silico Method |
| Country | : | India |
| Authors | : | Deepa V. || S. Sreekumar and C. K. Biju |
Abstract: Azadirachta indica A. Juss. (neem) is one of the Indian medicinal plants used as antidote to snake venom particularly against viper envenomation. In the present study 335 phytochemicals reported from Azadirachta indica were docked with Daboia russelii venom proteins, basic phospholipase A2 VRV-PL-VIIIa (PDB id 1OXL) and class II anticoagulant phospholipase A2 (PDB id 1VIP) using the tool AutoDock 4.2. To avoid error in lead identification, the top ranked hit molecules (ΔGbind<-10 kcal/mol) were docked using different docking tools such as SwissDock, PatchDock, iGemDock and Hex......
Keywords: AutoDock, Daboia russelii, Phospholipase A2, Venom, Viper , Azadirachta indica, Neem
[1]. L .S. Cruz, R. Vargas, and A.A. Lopes, Snakebite envenomation and death in the developing world, Ethnicity & Disease, 19(1), 2009, 42-46.
[2]. A. K. Mukherjee, and C. R. Maity, Biochemical composition, lethality and pathophysiology of venom from two cobras-Naja naja and Naja kaouthia, Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 131 (2), 2002, 125-132. [3]. P. H. De Silva, Snake fauna of Sri Lanka: With special reference to skull, dentition, and venom in snakes, (National Museums of Sri Lanka, 1980).
[4]. S. A. M. Kularatne, Epidemiology and clinical picture of the Russell's viper (Daboia russelii) bite in Anuradhapura, Sri Lanka: A prospective study of 336 patients, Southeast Asian Journal of Tropical Medicine and Public Health, 34 (4), 2003, 855-862.
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| Paper Type | : | Review Paper |
| Title | : | Congenital Chloride Diarrhoea |
| Country | : | India |
| Authors | : | Dr. Nandita Basak |
Abstract: Congenital chloride losing diarrhea (CLD) is a medical emergency case in pediatrics. It is a rare genetic disorder caused due to mutation of chromosome 7.It is commonly seen in Saudi Arabic countries ,It is seen in early neonates with features of absence of meconium,"urine like diarrhea" ,antennal finding shows hydraminous child in fetus ,fecal chloride concentration is more than 90mmol/l. The main treatment for CLD is continuous lifelong replacement of faecal loss water ,NaCl and KCl by salt substitution therapy, use of proton pump inhibitor etc ,with early diagnosis long term outcome is favourable .
[1]. Alam NH, Ashraf H. Treatment of infectious diarrhea in children. Paediatr Drugs. 2003;5:151–65. [PubMed]
[2]. Darrow DC. Congenital alkalosis with diarrhoea. J Pediatr. 1945;426:519–32.
[3]. Holmberg C, Perheentupa J, Launiala K, Hallman N. Congenital chloride Diarrhoea. Clinical analysis of 21 Finnish patients. Arch Dis Child. 1977;52:255–67. [PMC free article] [PubMed]
[4]. Lundkvist k,Ewald U, Lindgren PG,Congenital Chloride diarrhea :a perinatal differential diagnosis of small bowel atresia .Acta Paediatr 1996;85:295-298
[5]. Al-Hamad NM, Al-Eisa AA. Renal abnormalities in congenital chloride diarrhea. Saudi Med J. 2004;25:651–5. [PubMed]
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| Paper Type | : | Review Paper |
| Title | : | Analysis of Hepatic Protein Expression in Fisher-344 Rats Fed 2-Aminoanthracene |
| Country | : | United States |
| Authors | : | Walter, Jackson L || Govan, Richard D || Huang, Yisong || Linder Daniel F || Gato, Worlanyo E |
Abstract: The effect of 2-aminothracene (2AA) ingestion in Fisher-344 rats was examined. Protein expression was examined via bulk proteins isolated from the liver and analyzed on a mass spectrometry. 2AA is an aromatic amine that can be classified as a polycyclic aromatic hydrocarbon (PAH). 2AA is used in the manufacture of chemicals, dyes, inks, and it is also a curing agent in epoxy resins and polyurethanes. 2AA has also been found in tobacco smoke and cooked foods.......
Keywords: Aminoanthracene, proteomics, Fisher-344 rats, mass spectrometry, catalase, hemopexin
[1]. Agency ForToxic Substances And Disease Registry (ATSDR). 1995. Toxicological Profile For Polycyclic Aromatic Hydrocarbons (Pahs). US Department Of Health And Human Services, Public Health Service. Atlanta GA.<Http://Www.Atsdr.Cdc.Gov/Toxprofiles/Tp69.Pdf>
[2]. CaroloDos Santos K, Pereira Braga C, Octavio Barbanera P, Seiva FR, Fernandes Junior A, Fernandes AA. 2014. Cardiac Energy Metabolism And Oxidative Stress Biomarkers In Diabetic Rat Treated With Resveratrol. PlosOne. (7):E102775. Doi: 10.1371/Journal.Pone.0102775
[3]. Chen W, Syldath U, Bellmann K, Burkart V, AndKolb H. 1999. Human 60-Kda Heat-Shock Protein: A Danger Signal To The Innate Immune System. J Immunol162:3212-3219
[4]. Dail MB, Shack LA,Chambers JE, Burgess SC. 2008. Global Liver Proteomics Of Rats Exposed For 5 Days To Phenobarbital Identifies Changes Associated With Cancer And With CYP Metabolism. Tox. Sci. 106:556-569
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| Paper Type | : | Review Paper |
| Title | : | Rasibhavanti Lohani Mritani Survandite Verse Resembles As Nanotechnology- A Critical Study |
| Country | : | India |
| Authors | : | Shubham Jain || Swati Dubey || Madhuri Vindhyaraj || S.M.Parhate || Manoj Dash |
Abstract: Ayurveda, one of the ancient systems of medicine, holds a vast domain of traditional knowledge within himself. It is considered as the science of life and has been practiced in India since times immemorial. The system frequently employs unique metallic preparations known as Bhasma for the treatment of various ailments. The essence of these metals based drugs is that they function best when converted from their original metals to metal oxide forms.......
Keywords: Rasibhavan , Bhasma , Sindoor kalpana , Nano technology.
[1]. Vishva bandhu , commentary of Atharvaveda,(vishveshvaranand Vedic Research institute , Hoshiyarpur),1960 , 5/4/1 , 1/12/3
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| Paper Type | : | Review Paper |
| Title | : | Formulation and Evaluation of Etoricoxib Oro Dispersable Tablets by Direct Compression Method |
| Country | : | India |
| Authors | : | Lakshmi Usha Ayalasomayajula || Radha Rani Earle || Prasanthi T || V. Harika || N. RamyaSree |
Abstract: Oral disintegrating tablet (ODT) is defined as "A solid dosage form containing medical substances or active ingredient which disintegrates rapidly usually within a matter of seconds when placed upon the tongue". The main aim of the present study is to formulate Etoricoxib oral disintegrating tablets. Etoricoxib is a selective COX-II inhibitor which acts by inhibiting the COX–2 enzyme and decreases the incidences of side effects associated with these agents.......
Keywords: Etoricoxib, Oro-dispersable tablets, Direct compression method, Cross povidone, Cross carmellose sodium, Sodium starch glycolate, Calcium silicate
[1]. Lachman L, Lieberman HA, Kanig JL. The Theory And Practice Of Industrial Pharmacy: Varghese Publishing House; 3rd Ed. Bombay 1986; 293-342.
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| Paper Type | : | Research Paper |
| Title | : | Follicle Stimulating Hormone, Luteinizing Hormone, Prolactin, Progesterone and Testosterone Level in Chlamydia Trachomatis Infected Subject |
| Country | : | Nigeria |
| Authors | : | Ifeanyichukwu Martin Ositadinma || Dele-Ochie Patricia Ejenawome || Ebunu Ezekiel || Inege Lucky Chukwudi || Ngwu Amauche Martina |
Abstract: Background: Chlamydia trachomatis (Ct) is an obligate intracellular gram negative bacterial pathogen. Ct infection is a major and increasing public health problem worldwide. Currently, is the main cause of sexually –transmitted infection........
Keywords: progesterone, FSH, LH, infertility and Chlamydia trachomatis
[1]. Gurunath, S., Pandian, Z., Anderson, R. A., Bhattacharya, S. 2011. "Defining infertility--a systematic review of prevalence studies. Human Reproduction Update. 17 (5): 575–88.
[2]. Scholes, D. A., Stergachis, F. E., Heidrich, H., Andrilla, K., Holmes, K., Stamm, W.E., 1996. Prevention of pelvic inflammatory disease by screening for cervical chlamydial infection.New England journal of Medicine. 334: 1362-1366.
[3]. World Health Orgnisation. 1999. Contraceptive efficacy of testosterone-induced azoospermia in normal men, Task Force on methods for the regulation of male fertility. Lancet. 336 (8721): 955–959.
[4]. Korenromp, E.L., Sudaryo, M.K., deVlas, S.J., Gray, H.R; Sewankambo, N.K., Serwadda D., Wawer, M.J., Habbema, J.F., 2002. What proportion of episodes of gonorrhea and Chlamydia trachomatis in urogenital becomes symptomatic. International of Sexually transmitted Disease AIDS. 13: 91-101.
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| Paper Type | : | Research Paper |
| Title | : | Effect Of Surface Modification In Conventional Liposome With Lipophilic Agents |
| Country | : | India |
| Authors | : | Susmita Chandra || Mridula Misra || Kakali De || Indranil Banerjee |
Abstract: Conventional liposomes normally shows frequent uptake by reticuloendothelial system(RES). To reduce the RES uptake and to prolong the biological half life researchers aimed to prepare sterically stabilized liposomes containing charged or neutral particles as surface modifier for targeting various organs for therapeutic or diagnostic purposes........
Keywords: Biodistribution, liposome, Peptide synthesis, stability
[1]. S. Itakura, S. Hama, T. Ohgita and K. Kogure, Development of Nanoparticles Incorporating a Novel Liposomal Membrane Destabilization Peptide for Efficient Release of Cargos into Cancer Cells. PLOS One, 9(10), 2014,1-11
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