Series-2 (May-June 2019)May-June 2019 Issue Statistics
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| Paper Type | : | Research Paper |
| Title | : | Evaluation of Patients with Myocardial Infarction Undergoing Percutaneous Coronary Intervention (PCI) Using Low Dose Dobutamine Stress Echocardiography |
| Country | : | Iraq |
| Authors | : | Reem Jamal Jabir || Affan Ezzat Hasan || Qasim Mohammed Jumaah || Layth Rafea Taqa |
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: | 10.9790/3008-1403020106  |
Abstract: Coronary artery disease (CAD) is a spectrum of heart diseases which has the highest mortality in the world. Dobutamine stress echocardiography (DSE) has emerged as a versatile and simple tool to assess myocardial function and has been used extensively to determine myocardial viability and predict reversibility of ischemia induced reduction in functional parameters. Aim of study: assess the function and viability of ischemic myocardium of left ventricle (LV) before and after percutaneous coronary intervention (PCI) by using low dose dobutamine stress echocardiography (LDDSE) and to know the usefulness of low dose dobutamine (LDD) test in detecting the viable ischemic LV area. Method: DSE was performed........
Key words: Left ventricle, dobutamine stress echocardiography, wall motion score index, ejection fraction and percutaneous coronary intervention
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[4]. Pellikka P., Nagueh S., Elhendy A., Kuehl C. and Sawada S. (2007): American Society of Echocardiography recommendations for performance, interpretation, and application of stress echocardiography. Journal of American Society of Echocardiography; 20: 1021–41.
[5]. Armstrong W. and Ryan T. (2019): Feigenbaum's; a textbook of Echocardiography-8thed. Lippincott Williams and Wilkins (page 1596)..
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| Paper Type | : | Research Paper |
| Title | : | Shelf-stability of Gluten Free Cakes Produced from Quinoa Flour and Chia Gel |
| Country | : | Saudi Arabia |
| Authors | : | Essra Khaled Feddah || Maha Ahmed Hijazi || Magda M. Aly |
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: | 10.9790/3008-1403020712 |
Abstract: Bakery products, particularly cakes, represent one of the most consumed foods around the world. The development of gluten-free cakes with the same flavour and texture properties similar to the conventional wheat flour may be an interesting objective. In the market there is a challenge in increasing shelf life for gluten-free cakes, so the aim of this study was to assess shelf-stability of new formulations cupcake. Cake samples were prepared by replacing quinoa flour with wheat flour and chia mucilage gel with shortening at varying levels (0%, 25%, 50%, and 100%). The cake samples stored at 4, 20 and 37ºC for 8 days and analysed every two days. Microbial contents were determined using serial.........
Keywords: Shelf-stability, Gluten, Cakes, Quinoa, Flour, Chia Gel
[1]. Agrahar‐Murugkar, D., Zaidi, A., Kotwaliwale, N. & Gupta, C. 2016. Effect of Egg‐Replacer and Composite Flour on Physical Properties, Color, Texture and Rheology, Nutritional and Sensory Profile of Cakes. Journal of Food Quality, 39, 425-435.
[2]. Ammar, A. S. M. & El-Razik, M. M. A. 2013. Quality Characteristics Of Gluten Free Cake Produced From Cassava, Pumpkin And Potato Flours. Journal Food and Dairy Science, 4, 401 - 412.
[3]. Bennet, R. 1984. Bacteriological Analytical Manual, Food and Drugs Administration (FDA). Association of Official Analytical Chemists.
[4]. Bennion, E., Bent, A. & Bamford, G. 1997. The Technology of Cake Making, Springer Science & Business Media.
[5]. Berti, C., Riso, P., Brusamolino, A. & Porrini, M. 2005. Effect on appetite control of minor cereal and pseudocereal products. British Journal of Nutrition, 94, 850-858.
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| Paper Type | : | Research Paper |
| Title | : | Analysis of ground water and spring water quality in Aljabal Al akhdar |
| Country | : | Libya |
| Authors | : | Nagah A.S. Abubaker || Laila M. Alfageih || Abeer A. Hmoda |
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: | 10.9790/3008-1403021320 |
Abstract: Water samples were collected from 10 wells and 4 spring during two seasons (Autumn and Winter, 2015) to determine bacteriological, chemical and physical quality for ground water and spring water .Physicochemical parameters of water sample were obtained revealed that most of the results were within required levels by WHO. However, the MPN of coliform and feacal coliform were above recommended levels by WHO for all samples. The study showed that all wells and springs were highly contaminated with feacal E. coli. In present study the total coliform varied from 1380 to 1800 per 100 ml, while fecal coliform count varied from 0.4 to 1800 per 100 ml in water samples. The study provides indicators of presence of bacteria that represent a real health hazard in water sources in the Masa city.
[1]. Al-tomi, A .S. 2007,"Manual of bacteriological examination of drinking water". Biotechnology Research Center Libya, Vol. 10, No.19, pp. 230- 254.
[2]. Annual Drinking Water Quality Report Village of Niles Utility Number IL031 2010, 2005, Annual Water Quality Report for the period of January 1 to December 31.
[3]. Knepper, T.P. F. m Sacher, F.T. , Lange, H.J. , Brauch , F. , Karrenbrock, O. and Lahajan, L.B. 2014, " The Study of Bacterial Contamination in Drinking Waters of Urban and Rural Sources and Reservoirs in Iran (Guilan Province) Based on Total Coliform and Fecal Coliform" , World Applied Science Journal, Vol. 31, No. 6, pp. 1045- 1050.
[4]. WHO, 2011, "Guidelines for drinking-water quality", 4th Edn. World Health Organization, Geneva.
[5]. Adeleye, B.A. and Adetunji, A.M. 2013, " Surface and ground water pollution in Abata Ogun Agriculural Weltand", Journal of Natural Sciences Reserarch,vol. 3, No.13
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| Paper Type | : | Research Paper |
| Title | : | The Suppression of Anti-Microbial Peptides on Leukemic THP-1 Monocytes |
| Country | : | Taiwan |
| Authors | : | Yeu-Ching Shi || Jing Liu || David Yue-Wei Lee || Hung-Hung Sung || Cheng-Jeng Tai |
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: | 10.9790/3008-1403022125 |
Abstract: Leukemia is the most common hematological malignancy. Chemotherapy, differentiation induction, and stem cell transplantation are available options for usual clinical therapies inleukemia. Antimicrobial peptides (AMPs) exert antimicrobial activity against Gram-positive and Gram-negative bacteria, fungi, and viruses by various mechanisms. In this study, we found that two AMPs (LPSBD-0 and LPSBD-2) showed lip opolysaccharides (LPS) binding capacity could suppress leukemia. Moreover, these two AMPs could result in oxidative stress and apoptosis in THP-1 leukemic monocytes in a dosage-dependent manner, not depending on autophage. These results suggest that these AMPs may havethe potential to be developed as anti-cancer peptides forhuman leukemia.
Keywords: Leukemia, Antimicrobial peptides (AMPs), oxidative stress, apoptosis, THP-1 leukemic monocytes
[1]. Rajapakse N, Jung WK,Mendis E, Moon SH, Kim SK, A novel anticoagulant purified from fishprotein hydrolysate inhibits factor XIIa and platelet aggregation. Life Sci2005; 76: 2607-19.
[2]. Wang G, Mishra B,Epand RF,Epand RM, High-quality 3D structures shine light on antibacterial,anti-biofilm and antiviral activities of human cathelicidin LL-37 and its fragments. BiochimBiophysActa2014; 1838: 2160-72.
[3]. Huang HN,Rajanbabu V, Pan CY, Chan YL, Chen JY, Wu CJ, Enhanced control ofbladder-associated tumors using shrimp anti-lipopolysaccharide factor (SALF) antimicrobial peptide asa cancer vaccine adjuvant in mice. Mar Drugs 2015; 13:3241-58.
[4]. Huang TC, Lee JF, Chen JY,Pardaxin, an antimicrobial peptide, triggers caspase-dependent andROS-mediated apoptosis in HT1080 cells. Mar Drugs 2011; 9: 1995-2009.
[5]. Chan DI,Prenner EJ, Vogel HJ, Tryptophan- and arginine-rich antimicrobial peptides: Structures andmechanisms of action. BiochimBiophysActa2006; 1758: 1184-202
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| Paper Type | : | Research Paper |
| Title | : | Microbiological Assessment of Some Vegetables Obtained from Irrigated farms within Kaduna Metropolis |
| Country | : | Nigeria |
| Authors | : | James.Y || Gambo, J.B || Aliyu, A.M |
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: | 10.9790/3008-1403022630 |
Abstract: The microbiological assessment of fresh vegetables obtained from irrigated farms has revealed that it is the potential route for transmitting pathogens to humans. This study is aimed at investigating microorganisms commonly found in fresh vegetable farms in Kaduna north western Nigeria. Enumeration and characterization of Total bacterial count, Coliform count and Fungal isolates were determine using a standard methods. The isolated pathogenic bacteria genera and fungi from irrigated fresh vegetable samples includeStaphylococcus aureus, with 31.7% occurrenceEschericiacoli,had 28.6% occurrence, Pseudomonas aeruginosa,15.9 %occurrence while Bacillus spp,had 23.8%. For the fungal isolates,Aspergillusspp had 33.8%Penicilliumspp, 33% occurrenceFusariumspp had 25.6% while Sacharomycesspp and Rhyzopusspp had 3.6% occurrencesrespectively. The bacterial.........
Keywords: Microbiological assessment, Coliforms, Irrigation, Vegetables
[1]. Synder, R.I., Melo- Abreu, J.P. (2005). Frost Protection; fundamental practice and economics food and Agriculture organization of the united nation
[2]. Kalia and Gupta (2006). Fruit Microbiology, in Hiu, Y.H.J, Cano M.P., Sinha N.K. Handbook of fruits processing. Blackwell publishing 1:3-25
[3]. Dunn, R.A., Altamirano, J.V., Dietrich S.E., Johnson, D.R. (2004). International Journal of food Microbiology 16:55-59
[4]. Ibenyassine, (2007)." Bacterial" pathogens recovered from vegetable irrigated by waste water. Journal of Environmental Health 27: 111-116
[5]. Beuchat, C.R. (2009). Pathogenic Microorganisms Associated with Fresh Produce. Journal of Food Production 59:204-221
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| Paper Type | : | Research Paper |
| Title | : | Safe Use of Repeated Injection of 50nm Gold Nanorods on Reproductive Function in Male Albinorats: Histological, Morphometric, Hormonal and Oxidative Stress Parameters |
| Country | : | Egypt |
| Authors | : | Arwa A. Hassan || Ahmed S. Abdoon || Sawsan M. Elsheikh || Mohamed H. Khairy || Amina A. Gamaleldin || Sameh M. Elnabtity |
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: | 10.9790/3008-1403023139 |
Abstract: Gold nanoparticle have received a great focus todays. In this study, we investigated the effect of repeated administration of gold nanorods (AuNRs) on testicular function, sexual hormones and oxidative stress parameters. Twenty adult male albino rats were allocated into two equal groups each of ten rats. The first group received 1ml/kg saline I.P and the second group received 7.5μg/kg of AuNRs (50nm) I.P five consecutive days every month for two months. At the end of the second month, all rats from both groupswere sacrificed. Histopathological examination revealed no histopathological or morphometrical changes in testis,epididymis and seminal vecicle of AuNRs injected male rats. AuNRswere not detected by transmission electron microscope. Biochemical results detected that serum total and free testosterone significantly increased in AuNRs treated group in comparison with control group.........
Keywords: Repeated injection,AuNRs, Testicular function, sexual hormone, Cortisol, oxidative stress.
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[3]. Choi WI, Sahu A, Kim YH, Tae G. Photothermal Cancer Therapy and Imaging Based on Gold Nanorods. Ann Biomed Eng. 2011; 40: 534–46.
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[5]. Larson JK, Carvan MJ 3rd, Teeguarden JG, et al. Low-Dose gold nanoparticles exert subtle endocrine-modulating effects on the ovarian steroidogenic pathway ex vivo independent of oxidative stress. Nanotoxicology. 2014;8(8): 856–866.
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| Paper Type | : | Research Paper |
| Title | : | Seroprevalence of Chikungunya Virus in Febrile Patients in the Kenyan Coast |
| Country | : | Kenya |
| Authors | : | Elizabeth N. Ng'ang'a || Humphrey K. Wanjiku || Eddy Okoth Odari || Allan Ole Kwallah || Matilu Mwau |
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: | 10.9790/3008-1403024044 |
Abstract: Fever is one of the main complaints in patients seen at the Coast Provincial General Hospital in Mombasa, Kenya. There is anecdotal evidence to suggest that Chikungunya virus is a cause of some of those fevers, but published data is scanty.This was a hospital based cross sectional study conducted in patients presenting with fevers of unknown origins. We tested for CHIKV antibodies using Enzyme-linked Immunosorbent Assay (ELISA) and confirmed using Focus Reduction Neutralization Test (FRNT). Prevalence rates were determined using proportions and rates. Odds ratio was used to measure the association between CHIKV seropositivity and associated risk factors.Of the 488 eligible participants who were recruited for this study, 269 (54.7%) were males. The overall seroprevalence of CHIKV was 9.84% (48). Age, gender, yellow fever vaccination status, sub-county, occupation and clinical manifestations were not associated with seropositivity. At high temperatures CHIKV seropositivity peaked to 11.11% in 2014 and in 20.75% in 2015.Chikungunya is an important cause of fever in the Kenyan coast with a seroprevalence of 9.84%. There is a need to maintain constant epidemiological and entomological surveillance. Seroprevalence can be predicted using temperature and rainfall patterns.
[1]. Ravi V: Re-emergence of chikungunya virus in India. Indian J Med Microbiology 2006, 24(2):83-84.
[2]. Pialoux G, Gauzere BA, Jaureguiberry S, Strobel M: Chikungunya, an epidemic arbovirosis. Lancet Infect Dis 2007, 7(5):319-327.
[3]. Rezza G, Nicoletti L, Angelini R, Romi R, Finarelli AC, Panning M, Cordioli P, Fortuna C, Boros S, Magurano F et al: Infection
with chikungunya virus in Italy: an outbreak in a temperate region. Lancet 2007, 370(9602):1840-1846.
[4]. Epstein PR: Chikungunya Fever resurgence and global warming. Am J Trop Med Hyg 2007, 76(3):403-404.
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| Paper Type | : | Research Paper |
| Title | : | Recent Development and Evaluation for Effective Diagnosis and Treatment of Human Onchocerciasis, Using an Antigen Detection Dipstick Techniques: A Review |
| Country | : | Nigeria |
| Authors | : | Hafsat, M. || Galadima, U.S. || Maigari, A.K. || Nusaiba, B.S. || Aliyu, S.M. |
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: | 10.9790/3008-1403024549 |
Abstract: Onchocerciasis still remains a major hindrance to sustainable public health, farming and livestock development. However, the type of diagnostic test used for the detection of infections caused by onchocerciasis varies according to the epidemiological characteristics of the disease and the strategy for control. The clinical signs are not pathognomonic and the standard techniques for the detection of onchocerca species are not sufficiently sensitive. Despite several improvements in the techniques for onchocerca species detection, a high proportion of infections still go undetected as the majority of infections are chronic. This diagnostic challenge has led to the development.........
Key words: Onchocerciasis, Onchocerca volvulus, Diagnosis.
[1]. Morales Hojas R (2009). Molecular systematics of filarial parasite, with an emphasis on groups of medical and veterinary importance and its relevance for epidemiology. Infect Genet Evol 9:748-759.
[2]. Duke BO,Moore PJ,Vincelette J (2017). Factors influencing the passage of Onchocerca volvulus microfilariae into the urine. Tropenmed Parasitol 26:449-468.
[3]. Fuglsang H, Anderson J(2016). Microfilariae of Onchocerca volvulus in blood and urine before,during and after treatment with diethylcarbamazine. J Helminthol 48:93-97.
[4]. Gasser RB (2006). Molecular technologies in parasitology, with an emphasis on genomic approaches for investigating parasitic nematodes. Parasitolo (9) 48:9-11
[5]. Maia Herzog M, Shelley AJ, Bradley JE, Luna Dias AP, Calvao RH, Lowry C, Camargo M, Rubio JM, Post RJ, Coelho GE (2015). Discovery of a new focus of human onchocerciasis in central Brazil. Trans R. Soc Trop Med Hyg 93:235-239.
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| Paper Type | : | Research Paper |
| Title | : | A study to assess the level of awareness about probiotics and their usefulness in MBBS students of a medical college of Meerut |
| Country | : | India |
| Authors | : | Aditi Agrawal || Ravi Shastri || Rahul Bansal || Aditya Solanki || Akshay Chaudhary || Amar Gahlot |
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: | 10.9790/3008-1403025053 |
Abstract: Functional foods like probiotics deliver health benefits to host beyond nutrition and are very advantageous in improving host immunity but many health care providers are not aware of them. Hence this study was conducted to assess and increase the awareness of medical students regarding probiotics. The study was conducted on students of MBBS 2017 and 2018 batches of Subharti Medical College using a self made semi structured questionnaire. In this quasi experimental study, 49% students were initially aware about probiotics out of which 77% had previously used them. The awareness increased by 24% after giving an audio visual presentation and again administering the questionnaire.
[1]. Bassoum O, Sougou NM, Diongue M. Assessment of General Public‟s Knowledge and Opinions towards Antibiotic Use and Bacterial Resistance: A Cross-Sectional Study in an Urban Setting, Rufisque, Senegal. Pharmacy. 2018;(6):1-16.
[2]. Desai AJ, Gayathri GV, DS Mehta. Public‟s Perception, Knowledge, Attitude and Behaviour on Antibiotic Resistance - A survey in Davangere City, India. Journal of Preventive Medicine and Holistic Health. 2016;2(1):17-23.
[3]. Banerjee F, Raghunathan A. Knowledge, attitude and practice of antibiotic use and antimicrobial resistance: a study post the "Red Line‟ initiative. Current science. 2018;114(9):1866-1877.
[4]. Al-Nabulsi AA, Obiedat B, Ali R. Knowledge of probiotics and factors affecting their consumption by Jordanian College students. International Journal of Probiotics and Prebiotics. 2014;9(3):77-86.
[5]. Payahoo L, Nikniaz Z, Mahdavi R. Perceptions of Medical Sciences Students towards Probiotics. Health Promotion Perspectives. 2012;2(1):96-102.
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| Paper Type | : | Research Paper |
| Title | : | Isolation, Characterization and Identification of Biocellulose Producing Strains of Bacteria Isolated from Selected Tropical Fruits |
| Country | : | Kenya |
| Authors | : | Peter KariukiNjenga |
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: | 10.9790/3008-1403025459 |
Abstract: The principal objective of this research was to isolate and characterize cellulose producing bacteria from over ripe fruits through biochemical tests. The study majorly focused on the ability of the isolated strains of bacteria to synthesize cellulose and quantification of the synthesized cellulose so as to determine the modalities of scale up at the industrial level. The study involved culturing the over ripe fruits in Hestrin-Schram medium for 1 week then isolation of the bacterial strains for culturing in glucose yeast extract (GYE) agar from which the colony characteristics and further biochemical tests were carried out. In the project, 5 strains of bacteria were isolated from oranges, mangoes, water melon, lemon, grapes and pineapple. The isolates were 2 Gram positive rods and 3 Gram variables, catalase positive.........
Key words: Bacterial cellulose, Cellulose, Culture media, Gluconacetobacter strains, Tropical fruits.
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[3]. AmornratSuwanposri, PattarapornYukphan, Yuzo Yamada and DaungjaiOchaikul (2013), Identification and biocellulose production of Gluconacetobacter strains isolated from tropical fruits in Thailand, Maejo Int. J. Sci. Technol. 7(01), 70-82.
[4]. Andelib Y. A and Nuran D. A(2009), Isolation Of Cellulose Producing Bacteria From Wastes of Vinegar Fermentation, Vol. 1, October 20-22, 2009,Proceedings of World Congress On Engineering and Computer Science. San Francisco, USA.
[5]. Klemm, D., Schumann, D., Udhart, U., &Marsch, S. (2001) , Bacterial Synthesis Cellulose - Artificial Blood Vessels for Microsurgery. Progress in Polymer Science 26, 1561-1603.
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| Paper Type | : | Research Paper |
| Title | : | Toxicity Analysis of Tapinantus Globiferus in Swiss Albino Mice |
| Country | : | Nigeria |
| Authors | : | Abedo, A. J || Abdullahi, R. || Shettima, F. || Muhammed, I.S. || Irhue, A. E. || Idris, H. Y. || Tasie, C.P. || Tamba, Z. || Ogar, M.U. || Enoh, E. E. || Abedo, O.S. |
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: | 10.9790/3008-1403026070 |
Abstract: Medicinal plants with their derivatives play vital roles in the health of humans as well as animals and have long been knownto possess biological activity. The plant species Tapinantus globiferus, commonly known as mistletoe, is widely used in traditional medicine for the treatments of several diseases such as asthma, cancer, chronic fever, tinnitus, inflammations, dyspepsia, epilepsy, cough etc. The present studies aimed to evaluate acute toxicity of T. globiferus by using lorke's method as well as to determine the after effects on biochemical parameters and histopathological alterations. The study was conducted on albino rats in two phases. In the first phase, animals were divided into 4 groups of 3 animals each.S the first three groups (ABC and D) were treated intraperitoneally.......
Key words: Tapinantus globiferus, toxicity, phytochemical, biochemical, histopathological
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[5]. Jacobs, R.T.; Nare, B.; Wring, S.A.; Orr, M.D.; Chen, D.; Sligar, J.M.;Jenks, M.X.; Noe, R.A.; Bowling, T.S.; Mercer, L.T.; Rewerts, C.;Gaukel, E.; Owens, J.; Parham, R.; Randolph, R.; Beaudet, B.;Bacchi, C.J.; Yarlett, N.; Plattner, J.J.; Freund, Y.; Ding, C.; Akama,T.; Zhang, Y.K.; Brun, R.; Kaiser, M.; Scandale, I. and Don, R.(2011). SCYX-7158, an orally-active benzoxaborolefor thetreatment of stage 2 human African trypanosomiasis. PLoS Neglected Tropical. Diseases.,5(6):e1151.doi:10.1371/journal.pntd.0001151..
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| Paper Type | : | Research Paper |
| Title | : | Investigation of the Phytochemicals and some Biological Parameters of Ficus sycomorus Leaf Extracts |
| Country | : | Nigeria |
| Authors | : | Ayuk Eugene L. || Nwochi Samson P. || Ogugor Juliet C. || Simon Godwin I. || Ebiem- Kenechukwu Peace C. |
|
: | 10.9790/3008-1403027178 |
Abstract: The presence of phytochemicals in plants is responsible for their medicinal values. This work is aimed at investigating the phytochemicals and antimicrobial activity of Ficus sycamorus leaf extracts. Ficus sycamorus leaf extracts of five different solvents namely; distilled water, ethanol, methanol, n-hexane, petroleum ether were screened for the presence of phytochemicals. The result of the phytochemical analysis revealed the presence of alkaloids, flavonoids steroid, glycosides and tannins. The above extracts were also subjected to antimicrobial analysis. The antimicrobial analyses of the Ficus sycamorus leaf extracts for the five solvents revealed different levels.......
Key words: Investigation, Phytochemicals, Biological-Parameters, Minimum inhibitory concentration, Ficus sycamores
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[3]. Sofowora, A. (1993); Medicinal Plants and Traditional Medicine in Africa, Spectrum Books Ltd., Ibadan, Nigeria, 1993, 130
[4]. Orwa C, Mutua A, Kindt R, Jamnadass R and Anthony S (2009); Agro forestry database: A tree reference and selection guide version 4.0.
[5]. Keay R.W (1989) Trees in Nigeria, Clarendon press, Great Britain pp 240
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| Paper Type | : | Research Paper |
| Title | : | Prevalence and Treatment Seeking Behaviour among Malaria Patients in Some Clinics Inmayo Belwa Local Government Area, Adamawa State, Nigeria |
| Country | : | Nigeria |
| Authors | : | Sekari Hickson || Atinga A. |
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: | 10.9790/3008-1403027983 |
Abstract: Prompt access to early diagnosis and effective antimalarial treatment at Health Facility (HF) is one of the major strategies for reducing the burden of malaria. The aim of the study is to assess the prevalence and treatment seeking behaviour among malaria patients attending Health Facilities (HFs) in Mayo belwa Local Government Area, Adamawa State, Nigeria. Health facility-based cross-sectional study was carried out in Mayo belwa L. G.A., between July-August, 2018. Blood samples of 400 patients attending four HFs for malaria diagnosis were examined; thick and thin films were made and stained using standard parasitological procedures. Structured Questionnaires were administered to ascertain the socio-demography, time interval between onset of malaria illness and...........
Keywords: Health facilities; onset; Treatment seeking behaviour; Prevalence; Burden; Strategies; Medication; Malaria
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| Paper Type | : | Research Paper |
| Title | : | Methanolic Leaf Extract of Vernonia Amygdalina on the Testes of Streptozotocin Induced Diabetic Wistar Rats |
| Country | : | Nigeria |
| Authors | : | Victor A. Fischer || Ifoik F. Bassey || Christie E. Fischer |
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: | 10.9790/3008-1403028488 |
Abstract: This study aimed at investigating the effects of methanolic leaf extract of Vernonia amygdalina (VA) on the histology of the testes of streptozotocin (STZ) induced diabetic Wistar rats. Thirty male albino Wistar rats were divided into groups of six rats each for this study. Group A (Normal Control) and B (Diabetic Control) that received 0.5 ml dimethylsulphoxide (DMSO) only. Group C received 5i.u/kg body weight of insulin, Group D received 400mg/kg b.w of VA and Group E received 75mg/kg b.w of flavonoid rich fraction of VA. Group B,C,D and E animals were induced for diabetes by intraperitoneal injection of 40mg/kg b.w of STZ reconstituted in 0.5M sodium citrate buffer........
Keywords: Vernonia amygdalina, diabetes, spermatozoa
[1]. Akpaso, M. I; Igiri, A.O; Fischer;V.A; Fischer, C.E; Asuquo, O.R (2017). Combined Methanolic Leaf Extracts of Vernonia amygdalina (bitter leaf) and Gongronema latifolium Improves Sperm Parameter Impairment and Testicular Damage in STZ Induced Diabetic Wistar Rats. Journal of Biology, Agriculture and Healthcare. The International Institute for Science, Technology and Education (IISTE) Vol. 7 (6) 21-26
[2]. Akpaso, M.I, Atangwho, I.J; Akpantah, A; Fischer,V.A., Igiri, A.O, Ebong, P.E (2011). Effects of combined Leaf Extracts of Vernonia amygdalina (bitter leaf) and Gongronema latifolium (utazi) on the pancreatic B- cells of Streptozotocin Induced Diabetic Rats. British Journal of Medicine and Medical ResearchVol.1(2)
[3]. Ebong, P. E.,I.J. Atangwho, E.U. Eyong,C. Ukere, A.U. Obi (2006) Pancreatic B- cell regeneration. A probable parallel mechanism of hypoglycaemic action of Vernonia Amygdalina and Azadirachta Indica. Proceedings of International neem conference, Kuming China. Nov, 11-12, pp 83-89
[4]. Baris Altay M.D, Sevki Cetinkalp, B Basak, Bulent Semerci M.D (March, 2003). Streptozotocin induced diabetic effects on spermatogenesis with proliferative cell nuclear antigen immunostaining of adult rat testis.
[5]. De Young L, Yu D, Bateman RM, Brock GB. Oxidative stress and antioxidant therapy: their impact in diabetes-associated erectile dysfunction. J Androl 2004; 25(5):830-6.
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| Paper Type | : | Research Paper |
| Title | : | Effects of in-utero exposure to varied doses of alcohol on fetal growth and development in albino rats (rattus norvegicus) |
| Country | : | Kenya |
| Authors | : | Teresiah W. Musa || Kweri J. Kariuki || Thuo Reuben || Kafaya G. Kibe |
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: | 10.9790/3008-1403028997 |
Abstract: In-utero exposure to alcohol has been shown to disturb the normal development of various fetal organs. This is due to the fact that expectant mothers continue to use alcohol as a social drink and this has been shown to have injurious effects on the developing fetal organs. Though this data exist, data on whether this effects are dose or time dependent is lacking .This injurious effects on the developing fetal organs can help elucidate some of the behavioral and functional disorders observed in adulthood that are of unknown cause.The broad objective of this study was to determine the growth and developmental parameters upon administration of varying doses of ethanol,........
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