Abstract: Background: Sunflower seeds are widely used in the food, cosmetic, and pharmaceutical industries due to their numerous benefits. However, before introducing new products or ingredients into the market, safety evaluations such as irritation tests and risk assessments are necessary. To date, no clinical trials have been conducted on the topical application of sunflower seed oil and its potential to cause irritant contact dermatitis (ICD) or allergic contact dermatitis (ACD). This study aims to provide an overview of whether sunflower seed oil gel (Helianthus annuus L.) with a concentration of 20% causes ICD/ACD or not and determine if it has irritant potential, using the single closed patch test and repeated open application test......
Keywords: Sunflower Seed Oil, Patch test, Repeated open application test, Skin Irritation test
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