Version-3 (March-April 2017)
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| Paper Type | : | Research Paper |
| Title | : | Tranexamic Acid Use in the Total Hip and Total Knee Arthroplasty Population at an Academic Medical Center: a Retrospective Review of Postoperative Outcomes |
| Country | : | USA |
| Authors | : | Brianne E. Kaufman || Julie A. Murphy || Natalie Tuttle || Daniel Gehling |
 |
: | 10.9790/3008-1202030105  |
Abstract: Purpose Excessive blood loss and subsequent blood transfusions in orthopedic procedures have been associated with considerable morbidity and mortality. The primary objective of this study was to determine the incidence of perioperative blood transfusion after hip or knee arthroplasty with the use of tranexamic acid (TXA) versus standard of care. Methods: Any adult patient who underwent a total hip or knee arthroplasty between October 1, 2012 and September 30, 2015 was eligible for inclusion. Patients received 1000 mg of intravenous tranexamic acid preoperatively. Results.........
Keywords: arthroplasty, blood transfusion, thromboembolic complication, tranexamic acid.
[1] Iorio R, Davis CM, III, Healy WL et al, Impact of the economic downturn on adult reconstruction surgery,J Arthroplasty 25, 2010, 1005-1014.
[2] Rana AJ, Iorio R, Healy WL, Hospital economics of primary THA decreasing reimbursement and increasing cost, 1990 to 2008, ClinOrthop469, 2008, 355-361.
[3] Falck-Ytter Y, Francis CW, Johanson NA, Curley C, Dahl OE, Schulman S et al, Prevention of VTE in orthopedic surgery patients: antithrombic therapy and prevention of thrombosis, 9thed: American College of Chest Physicians evidence-based clinical practice guidelines,Chest 141(suppl), 2012, 278S-325S.
[4] Irwin A, Khan SK, Jameson SS, Tate RC, Copeland C, Reed MR, Oral versus intravenous tranexamic acid in enhanced-recovery primary total hip and knee replacement: results of 3000 procedures,Bone Joint J 95, 2013, 1556-1561.
[5] Parvizi J, Mui A, Purtill JJ, Sharkey PF, Hozack WJ, Rothman RH, Total joint arthroplasty: when do fatal or near-fatal compliationsoccur?,J Bone Joint Surg Am 89, 2007, 780-785..
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| Paper Type | : | Research Paper |
| Title | : | Studying the effect of Dielectric Barrier Discharges on the Leukemia Blood Cells Using Digital Image Processing |
| Country | : | Iraq |
| Authors | : | Sabah N. Mazhir || Alyaa H. Ali || Farah W. Hadi || Alaa N. Mazher |
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: | 10.9790/3008-1202030612 |
Abstract: In this research, Plasma physics and digital image processing technique are utilized. Dielectric Barrier Discharges (DBD) plasma at atmospheric pressure is used for the purpose of studying the plasma effect on the blood tissue, The first order statistical features are used to study the effect of plasma on the blood tissue. Different samples are used to reach the aim of this paper: the patients have leukemia and their leukocytes number is abnormal. By studying the results of statistical features (Energy, Mean, Entropy, Skewness, Kurtosis), it is concluded that the blood cells of the sample shows a good response to the cold plasma. So the plasma can be used as a treatment for the blood tissue for the persons with Leukemia............
Keywords: Cold Plasma, Dielectric Barrier Discharges, First-Order Statistics
[1]. P.C. Kong and E. Pfender, "Plasma Processes," in Carbide, Nitride and Boride Materials-Synthesis and Processing, 1st edition, ed., A. W. Weimer (Chapman & Hall, 1997), 359-383
[2]. K. D. Weltmann, TH. V. Woedtke, R. Brandenburg, and J. Ehlbeck, "Biomedical applications of atmospheric pressure plasma," Chem. Listy 102, 1450−1451, 2008. [3]. S. Cheruthazhekatt, M. Černák, and P. Slavicek, "Gas plasmas and plasma modified materials in medicine," J Appl Biomed, 8, 55–66, 2010.
[4]. I.E. Kieft, "Plasma Needle: exploring biomedical applications of non-thermal plasmas". Print service Technics Universities Eindhoven: 153. 2005. [5]. A. Kojtari, U. K Ercan, J. Smith, G. Friedman, R. B. Sensenig, S. Tyagi, Suresh G Joshi, Hai-Feng Ji and Ari D Brooks, "Chemistry for Antimicrobial Properties of Water Treated With Non-Equilibrium Plasma", Nanomedicine Biotherapeutic Discovery 2013, 4:1.
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| Paper Type | : | Research Paper |
| Title | : | Over-The-Counter (OTC) Use/Misuse of Panadol by Undergraduate Students of Taif Medical College, KSA |
| Country | : | Saudi Arabia |
| Authors | : | Nighat Kafil || Nighat Murad || Farzana Rizwan Arain || Nisreen Aref Al Bizrah |
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: | 10.9790/3008-1202031320 |
Abstract: Introduction: The irrational use of OTC medicines is a challenge in both developed and developing countries. In Saudi Arabia, the misuse of a variety of analgesics is common among high school and university students. Amongst medical students Panadol (Acetaminophen) is the most commonly used analgesic and also one of the most frequently used drugs for self-prescription. In this study, the Knowledge, Attitudes & Practices (KAP) towards OTC use/misuse of Panadol in undergrad students of Taif medical college was explored. Aim& methodology: To study the KAP of medical students in Taif city about the use/misuse of Panadol.KAP of 142 male and 139 female medical students from 2nd, 3rd and 4th year was assessed using a structured questionnaire about the use/misuse of Panadol............
Keywords: Over-the-counter, Panadol, analgesics.
[1]. Levy DM, Imundo LF. Nonsteroidal Anti-inflammatory drugs: A survey of practices and concerns of pediatric medical and surgical specialists and a summary of available safety data. Pediatr Rheumatol Online J 2010;8.
[2]. Jain A, Bhaskar DJ, Gupta D et al. Drug prescription awareness among the 3rd year and final year dental students: A cross-sectional survey. J Indian Ass Public Health Dentistry 2015;13:73-78.
[3]. Samarawickrama AAHS, Suraweera RK, Sivayaganthan C et al. A study on Paracetamol consumption by undergraduate students in the faculty of allied health sciences, University of Perdeniya. Int J Sci Research Pub 2014;4:1-6.
[4]. Saab S, Konyn PG, Viramontes MR et al. Limited knowledge of Acetaminophen in patients with liver disease. J Clin Transl Hepatol 2016;4:281-287.
[5]. Chen J, Murtaza G, Nadeem N et al. A questionnaire based survey study for the evaluation of knowledge of Pakistani university teachers regarding their awareness about Ibuprofen as an over the counter analgesic. Acta Poloniae Pharmaceutica-Drug Research 2014;71:337-342.
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| Paper Type | : | Research Paper |
| Title | : | Mosquito Species Diversity And Distribution in Three Riverine Communities in Taraba State, North-Eastern Nigeria |
| Country | : | Nigeria |
| Authors | : | Lamidi, B.T. || Alo,E.B. || Naphtali, R.S. |
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: | 10.9790/3008-1202032128 |
Abstract: Mostmosquitoes are nuisance and public health problem because the females consume blood and transmit diseases. Studies were carried out between September, 2015 and August 2016 to determine the composition and abundance of mosquito species in Taraba state, Nigeria. Indoor mosquitoes in riverine communities of Mayorenewa (Ardo Kola), Bali and Gyatanaure (Donga) were collected using Pyrethrum-Spray Catch complemented with electronic mosquito bat.A total of 3369 mosquitoes were collected comprising five genera: Anopheles 1686 (50.0%), Culex 1587............
Keywords: Mosquito, Shannon-Wiener and Simpson's indices, speciesdiversity,Taraba state
[1]. Service, M. W. Medical entomology for Students 3rdEd( Cambridge Univeristy press, UK,.Ed by Soper, R 2004)
[2]. Tyagi, B.K..Medical entomology:A Handbook of Medically important Insects and other Arthropods. (Pawan Kumar Scientific Publishers, India, 2003)
[3]. Segun, A.O; (1989). Tropical Zoology University Press Limited, Ibadan
[4]. Wikipedia (2014a). Mosquito.www.wikipedia.com. Accessed on 27/5/2014
[5]. Service, M.W.A Guide to Medical Entomology(The Macmillan Press Ltd., London and Basingstoke 1980)
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| Paper Type | : | Research Paper |
| Title | : | Effect of Gum Arabic on Liver Function And Antioxidant Enzymes of Sprague-Dawley Rats |
| Country | : | Sudan |
| Authors | : | Mohammed Babiker || Tarig Abbas || Mohammed Elimam Ahamed Mohammed |
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: | 10.9790/3008-1202032933 |
Abstract: The aim of this study was to investigate the effect of twelve weeks Gum Arabic dose on the liver functions and some antioxidant enzymes activity of 10 Sprague-Dawley rats. Methods: 10 normal Sprague-Dawley rats were fed one liter 10% of gum Arabic solution daily for 12 weeks. As a control group another 10 rats were not fed with gum Arabic. On week twelve, blood samples were collected from each rat and all of them were killed and the liver was obtained. Some of the liver was homogenized and the supernatant was collected. The liver function tests (direct bilirubin, total bilirubin, albumin, total proteins, Asparate transaminase, alanine transaminase and alkaline phosphatase)............
Keywords:Sprague-Dawley rats. Antioxidant activity, liver function, gum Arabic.
[1]. Mariana A Montenegro, Marίa L Boiero Lorena Valle, Claudio D Borsarelli. Gum Arabic: More Than an Edible Emulsifier in: Products and Applications of Biopolymers, Edited by Dr. Johan Verbeek, InTech, 2012, pp 1- 26.
[2]. Badreldin H Ali, Amal Ziada , Gerald Blunden. Biological effects of gum arabic: A review of some recent research. Food and Chemical Toxicology., 47: 1–8 (2009).
[3]. Ghassan F Alubaidy. Study The Biochemical Effect of Gum Arabic in Liver Injury and Blood Serum of Mice Induce by Gentamycin. Bas.J.Vet.Res ., 12(1): 243- 252 (2013).
[4]. Abdelkareem A Ahmed, Jaafar S Fedail, Hassan H Musa, Asghar Ali Kamboh, Amal Z Sifaldin, Taha H Musa. Gum Arabic extracts protect against hepatic oxidative stress in alloxan induced diabetes in rats. Pathophysiology., 22: 189–194 (2015).
[5]. Ali Eskandari, Mokhtar Heidari, Mohammad hosein daneshvar, sadegh taheri. Studying effects of edible coatings of Arabic Gum and olive oil on the storage life and maintain quality of postharvest Sweet Lemon (Citrus Lemontta). Intl J Agri Crop Sci ., 7(4): 207 (2013).
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| Paper Type | : | Research Paper |
| Title | : | Determination of Lead and Cadmium Contents and Microbial Contamination Assessment in Kohl used in Libyan Markets |
| Country | : | Libya |
| Authors | : | Amal Belaid || Asma Eswayah || Intisar El-Sharaa || Salma Shmaghi || Abdulkarem Tamer || Haya AlFassam || FulwahAlqahtani || Fadilah Aleanizy |
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: | 10.9790/3008-1202033438 |
Abstract: This study aims to determine some heavy metals such as lead (Pb) and cadmium (Cd) content in traditional eye cosmetics known as kohl, which is available in Tripoli markets in Libya. An analytical test was performed for ten kohl samples using flame atomic absorption spectrophotometer (AA280-FS). The overall mean (n= 6) concentration for each heavy metal was analyzed. The results of nine kohl samples (2-10) showed that the concentrations of lead and cadmium in these samples were within the range of 12.92-76.14% and 0.36-16.87% respectively. These high concentrations of Pb and Cd were over the safe limits set by the world health organization standards (WHO-2012/FAO-2013)............
Keywords: Kohl, Lead, Cadmium, poisoning, microbial contamination
[1]. F., S., Kohl a long history in medicine and cosmetics. Histoire Des Sciences Medicales, 1982. 17(2): p. 182-183.
[2]. Bouftini S, B.J., Turcant A, Achour, S. , Lead poisoning and use of cosmetic product: Kohl. International Journal of Research in Applied, Natural and Social Sciences, 2014. 2(5): p. 45-48.
[3]. Mahmood, Z.A., et al., Kohl (surma): retrospect and prospect. Pakistan Journal of Pharmaceutical Sciences, 2009. 22(1): p. 107-22.
[4]. Al-Ashban, R.M., M. Aslam, and A.H. Shah, Kohl (surma): a toxic traditional eye cosmetic study in Saudi Arabia. Public Health, 2004. 118(4): p. 292-8.
[5]. Al-Saleh, I., et al., Determinants of blood lead levels in Saudi Arabian schoolgirls. International Journal of Occupational and Environmental Health, 1999. 5(2): p. 107-14.
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| Paper Type | : | Research Paper |
| Title | : | Synergism effect of rosemary essential oil and some antibiotic against Escherichia coli isolated from clinical samples |
| Country | : | Iraq |
| Authors | : | Ghusoon A. Abdulhasan |
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: | 10.9790/3008-1202033942 |
Abstract: Urinary tract infections (UTI) are among the most common infections in humans worldwide, E. coli strains in particular are responsible for 80% of the UTI cases. Therefore, the study aimed to investigate the antimicrobial activity of Rosemary essential oil (EO) and three most antibiotics used for UTI treatment as well as determine the best combinations between the EO and these antibiotics against E. coli isolated from urine samples. The ability to form biofilm formation was performed and antimicrobial activity for antibiotics and rosemary EO were investigated by minimal inhibitory concentration (MIC) in broth microdilution method. The results showed that all isolates had the ability to produce biofilm (100%)...........
Keywords: E. coli, gentamicin, ciprofloxacin, Rosemary essential oil, synergism.
[1]. O. Al-Jiffri, Z. M.F. El-Sayed, and F. M. Al-Sharif. Urinary Tract Infection with and Antibacterial Activity of Some Plants Extracts. International Journal of Microbiological Research, 2 (1), 2011, 01-07.
[2]. A. Ronald .The Etiology of Urinary Tract Infection: Traditional and Emerging Pathogens. Dis.,49(2),2003, 71-82.
[3]. J. R. Johnson. Virulence Factors in Escherichia coli Urinary Tract Infection. Clin. Microbiol. Rev., 4 (1), 1991, 80-128.
[4]. J. Mandal, N. Srinivas Acharya, D. Buddhapriya, and S. Parija. Antibiotic resistance pattern among common bacterial uropathogens with a special reference to ciprofloxacin resistant Escherichia coli. Indian J. Med. Res., 136(5), 2012, 842-849.
[5]. H. Liu, Lin, Y. Lin, S. Yu, W. Wu and Y. Lee. Antimicrobial Susceptibilities of Urinary Extended Spectrum Beta-lactamase Producing Escherichia coli and Klebsiella pneumoniae to Fosfomycin and Nitrofurantoin in a Teaching Hospital in Taiwan. Journal of Microbiology, Immunology and Infection, 44, 2011, 364-368.
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| Paper Type | : | Research Paper |
| Title | : | Embryotoxic and Teratogenic Potentials of Salacia lehmbachii in Rats |
| Country | : | Nigeria |
| Authors | : | G.A. Essiet || G. C. Akuodor || A.D. Essien |
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: | 10.9790/3008-1202034348 |
Abstract: Use of herbal remedies in pregnancy may be deleterious to both mother and fetus. Against this background, aqueous and ethanol root bark extracts of Salacia lehmbachii, widely used herbal remedies for treatment of malaria in some localities were evaluated for embryotoxicity and teratogenicity in albino rats. One hundred and five pregnant rats weighing 170-180g were assigned 7 groups (n=15), labeled Control, 1-6. Control rats had 2 mL of distilled water. Groups 1, 2 and 3 received 250, 500 and 750mg/kg body weight of aqueous extract respectively while groups 4, 5 and 6 had similar doses of ethanol extract. Administration was orally on days 1 to 6 of gestation for implantation studies and days 7 to 15 for teratogenicity...........
Keywords: Embryotoxicity, pregnancy, teratogenicity, root bark, Salacia lehmbachii.
[1]. World Health Organization, 2008. Traditional medicine. Geneva. Available from: http://www.who.int/medicines/areas/ traditional/en/ [Accessed 11 May 2016].
[2]. J Barnes, Quality, efficacy and safety of complementary medicines: fashions, facts and the future. Part1Regulation and quality, British Journal of Clinical Pharmacology 55(3), 2003, 226–233.
[3]. L. Cuzzolin and G. Benoni, Safety issues of phytomedicine in pregnancy and pediatrics in K.J. Ramawat (Ed.), Herbal Drugs, Ethnomedicine to Modern Medicine. (Germany, Springer- Verlag, 2009).
[4]. A. K. Drew, Safety issues in herbal medicine: implication for the health profession, Medical Journal of Australia 166, 1997, 538–541.
[5]. M. Roulet, R. Laurini, L. Rivier and A. Calame, Hepatic veno-occlusive disease in newborn infant of a woman drinking herbal tea, Journal of Pediatrics, 112, 1988, 433-436.
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| Paper Type | : | Research Paper |
| Title | : | Emergence of New Snail Species and Cercariae on Jakara Dam |
| Country | : | Nigeria |
| Authors | : | Rabi Suraj Duwa |
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: | 10.9790/3008-1202034955 |
Abstract: Fresh water snails in Jakara dam were investigated for different types of cercariae. Snails were collected from different parts of the dam in Minjibir, Ugoggo and Gezawa local government area between October 2016 and January 2017 by hand picking only and placed separately in compartmented petridishes for cercarial shedding. Result showed that twenty one snail species from two families comprising Lymnaeidae and Planorbidae were encountered. Bulinus species collected are B. globosus morelet, B. reticulatus, B. truncatus rohlfsi, B truncatus truncatus Egypt, B jousseammei, B. succinoides and B. camerunensis. Fourteen species of Lymnea were encountered from different parts of the dam............
Keywords: Bulinus species, Cercariae, Jakara dam, Kano state, Lymnea species.
[1]. Abebe R, Abunna F, Berhane M, Mekuria S, Megersa B, Regassa A. (2010) Fasciolosis: Prevalence, financial losses due to liver condemnation and evaluation of a simple sedimentation diagnostic technique in cattle slaughtered at Hawassa Munincipal abattoir. Southern Ethiopia Ethiop Vet J.;14(1):39–51.
[2]. A. A. Aliyu, I. A. Ajogi, O. J. Ajanusi and R. C. Reuben (2014) Epidemiological studies of Fasciola gigantica in cattle in Zaria, Nigeria using coprology and serology Journal of Public Health and Epidemiology Vol. 6(2), pp. 85-91
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[4]. Betterton, C., Ndifon, G.T., Tan, R.M., (1988b). Schistosomiasis in Kano State, Nigeria, II. Field studies on aestivation in Bulinus rohlfsi (Clessin) and B. globosus (Morelet) and their susceptibility to local strains of Schistosoma haematobium (Bilharz). Annals of Tropical Medicine and Parasitology 82: 571–579.
[5]. Duwa, M.R. and Oyeyi, T.I (2009) The role of Jakara dam in the transmission of schistosomiasis Bayero Journal of Pure and Applied Sciences, 2(1): 58 – 63
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| Paper Type | : | Research Paper |
| Title | : | Knowledge, Attitudes and Use of Emergency Contraceptives among Female Students of the University of Nigeria, Nsukka |
| Country | : | Nigeria |
| Authors | : | Kosisochi Chinwendu Amorha || Patience Ijele Adayi || Ebere Emilia Ayogu || Chinwe Victoria Ukwe |
|
: | 10.9790/3008-1202035663 |
Abstract: Emergency contraception prevents pregnancy after unprotected sex or contraceptive failure. The objective of the study was to assess the knowledge, attitude and use of emergency contraceptives among female undergraduates in the University of Nigeria, Nsukka (UNN). This study was a cross-sectional, descriptive survey conducted among female undergraduates in UNN from June to August 2016. Data were collected by the 34-item structured, self-administered questionnaires and analyzed using the IBM Statistical Product and Service Solutions (SPSS) Statistics for Windows, Version 20.0 (IBM Corp, Version 20.0, Armonk, NY, USA). A total of 635 questionnaires were completed and returned (63.5% participation rate). Overall, 40% of the students had adequate knowledge of emergency contraceptives............
Keywords: Attitudes, emergency contraceptives, knowledge, use, University of Nigeria Nsukka
[1]. E.J. Kongnyuy, P. Ngassa, N. Fomulu, C.S. Niysonge, L. Kouam, and A.S. Doh. A survey of knowledge, attitudes and practice of emergency contraception among university students in Cameroon, BMC Emergency Medicine. 7(7), 2007.
[2]. S. Young, B. Griffin, and K. Vest. Active-Learning Instruction on Emergency Contraception Counseling, American Journal of Pharmaceutical Education, 77(5), 2013, Article 104.
[3]. H. Ameha, and F.Nebreed. Emergency contraception: potential clients and providers perspectives, Ethiopian Journal of Health Sciences, 16(1), 2006, 2–5.
[4]. F.A. Ahmed, K.M. Moussa, K.O. Petterson, and B.O. Asamoah. Assessing knowledge, attitude, and practice of emergency contraception: a cross-sectional study among Ethiopian undergraduate female students, BMC Public Health. 12, 2012, 110.
[5]. A. Bankole, I.F. Adewole, R. Hussain, O. Awolude, S. Singh, and J.O. Akinyemi. The incidence of abortion in Nigeria. International Perspectives on Sexual and Reproductive Health, 41(4), 2015, 170-181.
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| Paper Type | : | Research Paper |
| Title | : | New Insights into Aging Process with a Focus on Cell Morphology, Autophagy and Role of Macrophages and NFAT |
| Country | : | India |
| Authors | : | Manoj G Tyagi |
|
: | 10.9790/3008-1202036468 |
Abstract: Aging is a multifaceted process and involves cell senescence and apoptosis. Some key processes which may be involved could be the persistantmorphological changes in the cell structure for e.g cell blebbingand the role of physiological stressors. Amongst these are the macrophages which are on the front line of host defense.They possess an array of germline-encoded pattern recognition receptors/sensors (PRRs) that recognize pathogen-associated molecular patterns (PAMPs) and which activate downstream effectors/pathways to help mediate innate immune responses and host defense. Innate immune responses include the rapid induction of transcriptional networks that............
Keywords: Macrophages, autophagy, cell blebbing, NFAT-5, aging
[1]. B. Levine, N. Mizushima, and H. W. Virgin, "Autophagy in immunity and inflammation," Nature, vol. 469, no. 7330, pp. 323–335, 2011.
[2]. Keisuke Mochida, Yu Oikawa, Yayoi Kimura, Hiromi Kirisako, Hisashi Hirano, Yoshinori Ohsumi& Hitoshi Nakatogawa.Receptor-mediated selective autophagy degradesthe endoplasmic reticulum and the nucleus.Nature, 2015, 522 ,359-374
[3]. P. Boya, F. Reggiori, and P. Codogno, "Emerging regulation and functions of autophagy," Nature Cell Biology, vol. 15, no. 7, pp. 713–720, 2013.
[4]. C. C. Mihalache and H.-U. Simon, "Autophagy regulation in macrophages and neutrophils," Experimental Cell Research, vol. 318, no. 11, pp. 1187–1192, 2012.
[5]. Z. Yang and D. J. Klionsky, "Mammalian autophagy: core molecular machinery and signaling regulation," Current Opinion in Cell Biology, vol. 22, no. 2, pp. 124–131, 2010
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| Paper Type | : | Research Paper |
| Title | : | Effect of Aspirin on C- Reactive Protein as a Marker of Risk in Unstable Angina |
| Country | : | India |
| Authors | : | Lincy Joseph || Mathew George || Bhagya Krishnan |
|
: | 10.9790/3008-1202036970 |
Abstract: Angina, is the term used for chest pain caused by reduced blood flow to the heart muscle. Angina is typically described as squeezing, pressure, heaviness, tightness or pain in chest. Aspirin, also known as acetyl salicylic acid (ASA) is a medication used to treat pain, fever and inflammation. Aspirin is also used long term to help prevent heart attacks, strokes and blood clots in people at high risk. Elevated levels of C- reactive protein, a marker for systemic inflammation, have been found among individuals with stable and unstable angina. Elevated circulating levels of C- reactive protein, an inflammatory marker, increase the risk of thrombotic cardiovascular diseases such as myocardial infarction.
Keywords: Unstable angina, Aspirin, C-reactive protein, Cardiovascular diseases.
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[5]. Michelle A Albert, MD, Ellie Danielson, MIA, Nader Rifai, PhD, Paul M Ridker,MD, "Effect of statin therapy on C- reactive protein levels." JAMA, July 2001-vol 286, no.1
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| Paper Type | : | Research Paper |
| Title | : | Acute Toxicity and Lethality of Gladiolous psittacinus |
| Country | : | Nigeria |
| Authors | : | Moshood Abdullah Ishaq || Ola-MudathirFausat Kikelomo || Efere MartinsObuotor || AbdulrahimMarufat Iyaboale || Idris Adegbite Wasiu |
|
: | 10.9790/3008-1202037175 |
Abstract: The use of Gladiolous psittacinusplant in traditional medicine is drastically increasing across the country Nigeria. This study was therefore conducted to evaluate the safety level of G. psittacinus using acute toxicity test (determination of median Lethal Dose; LD50) and the Brine shrimp lethality assay (BSLA). Histopathological analysis of the liver of rats orally administered with different dosages of G. psittacinus (1600, 2800 and 5000 mg/kg body weight) was also conducted. Results revealed amedian lethal dose (LD50) of the aqueous extract of G. psitticanus as 2116.60 mg/kg body weight. Similarly, the lethality concentration (LC50) of methanolic extract of G...............
Keywords: Gladiolous psittacinus, brine shrimp, toxicity, medicinal plant, LD50, oral dose
[1]. Adjanohoun F.J., Ake A. L., Floret J.J., Guinko S., Koumare M. and Ahyi A.M. (1985).Contribution of the ethnobotanicals and flora in Mali to traditional medicine. Paris: Pharmacopia
[2]. Al-Ghaithi F., Mandouh R., El-Ridi M.R., Adeghate E., Amiri M.H. (2004).Biochemical effect of citrullus colocynthis in normal and diabetic rats. Mol Cell Biochem., 261: 143-9.
[3]. Alluri V. K., Tayi V. N. R., Dodda S., Mulabagal V.,Hsin-Sheng T., and Gottumukkala V. S. (2006). Biological Screening of Medicinal Plants Collected from Eastern Ghats of India Using Artemia salina (Brine Shrimp Test) International Journal of Applied Science and Engineering. 4, 2: 115-125
[4]. Ameh, S. J., Obiageri O. Obodozie, Patrick O. Olorunfemi, Innocent E. Okoliko and Nelson A. Ochekpe (2011). Potentials of Gladiolus corms as an antimicrobial agent in food processing and traditional medicine Journal of Microbiology and Antimicrobials Vol. 3(1), pp. 8-12
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| Paper Type | : | Research Paper |
| Title | : | Comparative In Vitro Equivalence Evaluation of Some Loratadine Generic Tablets Marketed in Bangladesh |
| Country | : | Bangladesh |
| Authors | : | Tasnim Motaher Oishi || Sanjida Munna || Zainab Noor || Sajan Das || Rumana Akhter || Sumaiya Huque || Mohammad Shahriar |
|
: | 10.9790/3008-1202037681 |
Abstract:Loratadine is a potent, rapidly effective and long-acting non-sedative, histamine H1 receptor antagonist, with anti-allergic properties. The purpose of this research work was to evaluate the pharmaceutical equivalent of six different brands of loratadine 10 mg tablets using various pharmacopoeial and nonpharmacopoeial tests with special landmark on in vitro dissolution study and with different price ranges purchased from retail pharmacies of Bangladesh. All brands complied with the official specification for friability, uniformity of weight and disintegration time but four brands did not comply with the official specification for hardness................
Keywords: Loratadine, In vitro equivalence, Dissolution, Difference factor (f1), Similarity factor (f2)
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of some Desloratadine generic tablets marketed in Bangladesh. International Journal of Applied Research, 3(2), 2017, 288-293.
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| Paper Type | : | Research Paper |
| Title | : | The Calvary After The Abort Due To Varied Attempts To Treat Rheumatoid Arthirtis By Tnfα Inhibitors And The Final Resolution, Owing To Classic And Orthodox Remedies In An Old Lady Suffering From A Complex Syndrome:A Special Case Report |
| Country | : | Italy |
| Authors | : | Lorenzo Martini |
|
: | 10.9790/3008-1202038283 |
Abstract: Scope of thismodest case report is to demonstratethatitisnotimpossible to conciliate the usage of common and orthodoxmedicaments to combatdifficultoutcomesderiving from an inconceivable series of syndroms in a single individual. The very importance I want this paper has to herald is that TNFα inhibitorsmayresultperilous and sometimesletal (in peculiarcases) for elder, besides to propose a treatment of thatcomplicatedsyndrome by the aids of common and orthodoxremedies.
Keywords: TNFα inhibitors, INR, diabetesmellitustype 1, psoriaticrheumatoidarthritis.
[1]. OtsukaF, Amano T, Uchida H, Ogura T, Makino H.;Acase of idiopathicdeepveinthrombosis improved withglucocorticoidtherapy.Haematologia (Budap). 1999;29(4):305-1
[2]. Johannesdottir SA, Horváth-Puhó E, Dekkers OM, Cannegieter SC, Jørgensen JO, EhrensteinV, Vandenbroucke JP, Pedersen L, Sørensen HT.:2013; Use of glucocorticoids and risk of venousthromboembolism: a nationwidepopulation-based case-control study;2013.JAMA Intern Med.13;173(9):743-52.
[3]. Ruban P, Yeo SJ, Seow KH, Tan SK, Ng SC.; Deepveinthrombosisaftertotalknee replacement.2000;AnnAcadMed Singapore,;29(4):428-33.
[4]. Yunjian Zhang1 , Yawei Shi1 , Runyi Ye1 , Nan Shao1 , Fushun Pan2 , Ying Lin1 , Shenming Wang1 ; Diabetesmellitus-associatedhyperglycemiais a riskfactor for recurringdeepveinthrombosis and post-thromboticsyndrome-a cohortstudy;2016: Int J ClinExpMed 2016;9(9):17739-17749
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| Paper Type | : | Research Paper |
| Title | : | Survey of endophytic Alternaria species isolated from plants in the Brazilian restinga biome |
| Country | : | Brazil |
| Authors | : | Maria das Graça M. Freire || Vicente Mussi-Dias || Thalles C. Mattoso || Daniel A. Henk || Ana Mendes || Maria Lígia R. Macedo || Carolina Turatti || Suzy W. Machado || Richard Ian Samuels |
|
: | 10.9790/3008-1202038494 |
Abstract: Saprophytic, endophytic and pathogenic Alternaria have been isolated from a wide range of environments. Endophytic fungi from Brazilian "restingas" have not been studies to date. Here endophytic Alternaria isolates from a range of restinga plants were investigated. One hundred and fifty seven plant species were screened, from which 71 endophytic Alternaria isolates were provisionally identified. Nineteen isolates were selected for DNA sequencing and phylogenetic analysis. All 19 isolates were confirmed as Alternaria with a division into two distinct clades. Seventeen of these isolates were screened for anti-fungal activity against 4 species of plant pathogenic fungi........
Keywords: Antagonism, bioactive compounds, coastal ecosystem, diversity, tropical plants.
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