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| Paper Type | : | Research Paper |
| Title | : | Design and Characterization of Effervescent Gastro Retentive Floating Tablets by Using Venlafaxine Hcl as a Model Drug |
| Country | : | India |
| Authors | : | Asfia Kauser || Ayesha Haseena || Faheem Unnisa Begum || Taiyaba Fatima |
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: | 10.9790/3008-1203020111  |
Abstract: In the present research work the gastro retentive floating matrix formulation of Venlaflaxine hydrochloride by using various hydrophillic polymers. Initially analytical method development was done for the drug molecule. Absorption maxima was determined based on that calibration curve was developed by using different concentrations. Gas generating agent sodium bicarbonate concentration was optimized. Then the formulation was developed by using different concentrations of polymers of various grades of HPMC and Guar gum. The formulation blend was subjected to various preformualation studies, flow properties and all the formulations were found to be good indicating that the powder blend has good flow properties............
Keywords: Venlaflaxine hydrochloride, HPMC polymers, Floating tablets.
[1]. Leon Lachman, Herbert A. Liberman, the Theory and Practice of Industrial Pharmacy: P.293-302.
[2]. Robinson Jr, Lee V.H.L, Controlled drug delivery: Fundamentals and Applications, 2nd edn. Marcel Dekker, New york: (1978) P.24-36.
[3]. Brahmankar D.M, Jaiswal S.B, Biopharmaceutics and Pharmacokinetics a treatise, 1st ed. Vallabh prakashan; New Delhi: (1995) P.64-70.
[4]. Chein Y.W, Novel Drug Delivery Systems, 2nd ed.: Marcel Dekker; New York: (1992) P.4-56.
[5]. Ansel, Pharmaceutical Dosage form and Drug Delivery System, Lipincott, 7th edition: P. 553.
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| Paper Type | : | Research Paper |
| Title | : | Ethnobotanical Survey of Uses of Leguminosae in Raipur District |
| Country | : | India |
| Authors | : | Dewangan P || Acharya V |
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: | 10.9790/3008-1203021217 |
Abstract: Plants have been the part of life forms even with the progenitors of man. Term "Ethnobotany" was coined to denote use of plants by human being.Ethnobotany deals with the direct relationship of plants with man. The term today has come to denote the entire realm of direct relationship between plant and man. Plants show enormous diversity in the form of Algae, Fungi, Bryophytes, Pteridophytes, Gymnosperms, and Angiosperms of which later are the most diversified plants. Present study focuses on ethnobotanical study of one of the largest family of Angiosperms, the family Leguminosae, of Raipur city area. Leguminosae include three subfamilies viz: Papilionoideae, Caesalpinoideae and Mimosoideae. The family has approximately 18,000 species grouped into around 650 genera with cosmopolitan distribution............
Keywords: Leguminosae, ethnobotany, herbal medicine.
[1]. Agharkar, S.P, Medicinal Plants of Bombay presidency (Scientific Publishers, Jodhpur India) 1991.
[2]. Ambasta, S. P., The useful plants of India (Publication, and Information on: CSIR, New Delhi) 1986.
[3]. Banerjee M (2002) Public policy on Ayurveda. Economic and political weekly. 37: 1136-1146.
[4]. Cotton, C.M., Ethnobotany : Principles and Applications (John Wiley and Sons, Chichester. New York. Pp-6-8, 15-18.) 1996.
[5]. Dastur J F, Useful Plants of India and Pakistan (Taraporevala and sons, Bombay, India) 1964.
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| Paper Type | : | Research Paper |
| Title | : | Factors Affecting Biodegradation of the Organophosphorus Insecticide Diazinon by Bacterial Mono-Culture of Bacillus Sefensis 7, Isolated From the Rhizosphere of Date Palm Tree |
| Country | : | Egypt |
| Authors | : | Magda M. Aly || Buthinah A. Al-aidaroos || Fahad A. Alfassi |
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: | 10.9790/3008-1203021826 |
Abstract: Due to widespread use pesticides for crop protection, they are considered as contaminants in the, environmental matrices such soil which are exposed to large quantities. Three isolates from soil samples using enrichment culture technique have been isolated and grown in the minimal growth medium where Diazinon served as a sole carbon source (60 mg/l). Total three bacterial strains were screened for Diazinon degradation. The most active one was isolate BMNF7 (33% degradation. Lower degradation percentages were recorded for the two other isolates, BMRF3 and BMTF 8 (21-30%). The isolate BMNF7 was identified by morphological and biochemical studies as Bacillus sp. and identification............
Keywords: Bacillus, Diazinon, Insecticide, Degradation, 16srRNA.
[1]. Abouseada, N., Moheb, M. and Moez, P. (2016). Impact of MALDI-TOF in the Routine Diagnostic Microbiology Laboratory in Alexandria University, Egypt. Egypt. J. Med. Microbiol., 3:616-620.
[2]. Adawiyah, I. (2008). Isolation, characterization and identification of microorganism from soil contaminated with pesticide (Doctoral dissertation, Universiti Malaysia Pahang).
[3]. Agarry, S.E., Olu-Arotiowa, O.A., Aremu, M.O., and Jimoda, L.A. (2013). Biodegradation of Dichlorovos (Organophosphate Pesticide) in soil by bacterial isolates. Journal of Natural Sciences Research, 3(8):12-16.
[4]. Agwa H, Aly MM, Bonaly R (2000). Isolation and characterization of two Streptomyces species produced non polyenic antifungal agents. J. Union Arab Biol. 7:62-82.
[5]. Anderson, M.J., Gorley, R.N. and Clarke, K.R. (2008). PERMANOVA for PRIMER: Guide to Software and Statistical Methods. PRIMER-E: Plymouth, UK. 214 pp
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| Paper Type | : | Research Paper |
| Title | : | Molecular characterization of some food borne pathogens in soft cheese samples collected from Jeddah, Saudi Arabia |
| Country | : | Egypt |
| Authors | : | Sanaa Tork || Safa Qutub Alfattani || Tahani Mansour Al-Kahtani || Madeha N. Al-Seeni || Magda M. Aly |
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: | 10.9790/3008-1203022734 |
Abstract: The growing industrial attention toward rapid methods and the wide use of nucleic acid amplification techniques has led for developing and applying of PCR based methods for food-borne pathogens recognition. In the current study, 20 cheese samples, collected from a local supermarket of Jeddah, Saudi Arabia were examined for the presence of metals and some pathogenic bacteria. Cheese content of Na+ and K+ were found to be higher in fresh cheese than other elements. Cr2+, Ni2+, Zn2+ and Al3+ were detected at low concentrations in cheese. Additionally a multiplex PCR method was developed for detection of Salmonella spp., Listeria monocytogenes and Escherichia coli...........
Keywords: Soft cheese, E. coli O157:H7, Listeria monocytogenes, Salmonella spp, Universal – Multiplex- primer
[1]. Alexandre M, and Prado V. Detection of Shiga toxin-producing Escherichia coli in food. Expert Review of Molecular Diagnostics, 2003; 3: 105–115.
[2]. Aly M, Al-Seeni M, Qusti S, El-Sawi N. Mineral content and microbiological examination of some white cheese in Jeddah, Saudi Arabia during summer 2008 Food and Chemical Toxicology, 2010; 48: 3031–3034
[3]. Andrews W H, Hammack T S. Salmonella. In: United states food and drug administration. Bacteriological Analytical Manual, 8. ed. 2001, p.5.01-5-20.
[4]. Anonymous. Microbiology of food and animal feeding stuffs. Protocol for the validation of alternative methods (EN ISO 16140). European Committee for Standardization, AFNOR, Paris, France, 2002.
[5]. Aziz NH. Etiology of toxin producing fungi from the class of deuteromycetes occurring in various feed products. Ph.D. Thesis, Agricultural University,Cracow, Poland, 1987.
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| Paper Type | : | Research Paper |
| Title | : | Studies on Skin Sensitivity to Various Allergens in Jeddah, Saudi Arabia Using Skin Prick Test |
| Country | : | India |
| Authors | : | Eman Beyari || Hussein A. Almehdar |
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: | 10.9790/3008-1203023540 |
Abstract: Skin prick test is one of the more important diagnostic tests against allergic diseases, it uses a synthesized allergic extracts from different allergens. In this study skin prick test was done on 83 allergic persons and 20 controls (54 male and 49 female). The test was done in the Allergic Clinic in the King Abdulaziz University Hospital with 9 different allergens which were isolated from Jeddah city. The used allergens were extract of 2 species of house dust mite, extract of house dust and extracts of 6 species of identified fungi. The extracts were used in the skin prick test and compared with the same commercial allergen extracts, imported from Omega company, Canada.............
Keywords: Allergerns, Skin prick, Patients, Diagnosis
[1]. Aas K, Belin L. (1974). Suggestion for biologic qualitative testing and standardization of allergen extracts. Acta Allergol., 29:238-40.
[2]. Al Frayh, A., Hasnain, S., Gad Al Rab, M., Schwarts, B. and Al Sedairy, S. (1997) House Dust Mite Allergen in Saudi Arabia : Region Variations and Immune Response, Annals of Saudi Arabia 17(2) : 156- 160.
[3]. Al Nahdi, M. and Al Qurain, A. (1989) IgE level in Saudi Arabia. Allerg Immunol., 21(8):308-310.
[4]. Arshad, S.H. (2002) Allergy, London: Churchill Livingstone.
[5]. De Fátima Maçãira, E. Algranti, E. Medina Coeli Mendonça, E. and Antônio Bussacos, M. (2007). Rhinitis and asthma symptoms in non-domestic cleaners from the Sao Paulo metropolitan area, Brazil, Occup Environ Med. 64(7):446-453.
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| Paper Type | : | Research Paper |
| Title | : | Betterment the production of prodigiosin that was produced from Serratia marcescen by means mutations |
| Country | : | Iraq |
| Authors | : | Hussam Mahmood Hasan |
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: | 10.9790/3008-1203024145 |
Abstract: Serratia marcescens was exposed to mutation for becoming better the production of prodigiosin (quantitatively and qualitatively) and examined it as antibacterial activities. One isolate of S.marcescen (Wild) was exposed to different kinds of antibiotics (Gentamycin 10μg/ml) to produce mutant isolates from S.marcescen and examined to produce prodigiosin. The isolate that produce the largest amount of prodigiosin among four isolates was used for more studies. Staphyllococcus Baciilus, E.coli, and Pseudomonas were exposed to prodigiosin for testing inhibiting activity of it against these bacterial strains.
Keywords: Serratia marcescens, prodigiosin, Gentamycin, mutation
[1] W.S. Richardson, M.C. Wilson, J. Nishikawa, R.S. Hayward .The well-built clinical question: a key to evidence-based decisions. ACP J Club 123, 1995, A12–13.
[2] American Dental Association. Policy on evidence-based dentistry: introduction. http://www.ada.org/1754.aspx. Accessed 8 Mar 2015. 2008
[3] G.E. Gray, L.A. Pinson. Evidence-based medicine and psychiatric practice. Psychiatr Q 74, 200, 387–99.
[4] L.M. Prisant. Hypertension In: Conn RB, Borer WZ, Snyder JW, editors. Current Diagnosis. Philadelphia: W.B. Saunders.1997, 349–59.
[5] D.L. Sackett, W.M. Rosenberg, J.A. Gray, R.B . Haynes, W.S. Richardson. Evidence based medicine: what it is and what it isn't. Brit Med J 312, 1996, 71–72.
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| Paper Type | : | Research Paper |
| Title | : | A Study On Effect Of Pharmacist Mediated Patient Counseling In Hypertensive Patients In Terms Of Knowledge, Compliance And Quality Of Life |
| Country | : | India |
| Authors | : | Chaudhary Gp || M. Navyashree || D. Sen Roy || R.Srinivasan |
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: | 10.9790/3008-1203024654 |
Abstract: To create awareness about hypertension in order to improve their quality of life. Free health camps were conducted; screening of blood pressure was done. Data were collected based on medical history, family history, food and social habits and so on. Individual counselling was done in the respective languages in which they were comfortable. Feedback was collected from the patients regarding their satisfaction towards the camp and the services provided to them. Also, patient information leaflets containing the basic information about hypertension were provided to each patient to enhance their knowledge even further.............
Keywords: Hypertension, Social Habits, Medical history, Counselling, Quality of life.
[1]. Williams Lippincott, Wilkins, practical cardiology evalution and treatment of common cardiovascular disorders, 2008 :219-227
[2]. Pawar S, Lokhande KD, Padma S, Diwan A. Effect of pharmacist mediated patient counseling in hypertensive patients in terms of knowledge , compliance and lifestyle modification. Int J Pharm Pharm Sci. 2014;6(4):277–2781.
[3]. Biradar SS, Reddy S, Raju SA, Kapatae R. Assessment of pharmacist mediated patient counseling on knowledge, attitude and practices on hypertension in compliance with antihypertensive drugs in south Indian city. Int J Pharm life Sci. 2012;3(6):1733–1738.
[4]. Biradar S., Rajashekhar K, Srinivas R, S A R. Role of pharmacist towards knowledge attitude and practice in compliance with hypertension in north karanataka in south indian. Int Res J Pharm. 2012;3(5):17–20.
[5]. Biradar SS, Rajashekhar K, Srinivas R, Raju SA. Assesment of pharmacist mediated patient counseling on hypertension incompliance with quality of life in south indian city. 2012;3(1):206–209.
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| Paper Type | : | Research Paper |
| Title | : | Lipases, Definition, and their Application |
| Country | : | China |
| Authors | : | Waznah Moayd || Yunjun Yan |
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: | 10.9790/3008-1203025560 |
Abstract: Esterase and lipase have been consisted of α/β hydroxylase super family that characterized primarily by their α/β hydroxylase fold (common fold), which is in the center, pre-dominantly parallel β-sheet and flanked via the connections of α-helical. Nucleophilic elbow is an esterases and lipases that shared the characteristic sequence motifs (GXSXG). The residues of these amino acids compose a triad of catalyse in the specific-order (serine – aspartic acid - histidine) in the chain of polypeptide. Consequently, the most of lipases and esterases resemble serine-proteases..........
Keywords: Lipase; Definition; Properties; Applications
[1]. D. Ollis, E.C., M. Cygler, B. Dijkstra, F. Frolow, S. Franken, M. and S.J.R. Harcel, I. Silman, The hydrolase fold. Protein Eng, 1992. 5(197–211).
[2]. M. Nardini, B.W.D., Hydrolase fold enzymes: the family keeps growing. Curr Opin Struct Biol, 1999. 9(732–737).
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[4]. L. Brady, A.M.B., Z.S. Derewenda, E. Dodson, G. Dodson, S. Tolley, J.P. Turkenburg, L. Christiansen, B. Huge-Jensen, L.
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| Paper Type | : | Research Paper |
| Title | : | Large Obstructed Epigastric Hernia: an Unusual Presentation |
| Country | : | India |
| Authors | : | Dr. Partha Pratim Mandal || Dr. Tanushree Mondal || Dr .Syed Shahjahan Siraj |
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: | 10.9790/3008-1203026163 |
Abstract: Epigastric hernia is a rare form of ventral hernia. Obstructed epigastric hernia containing gut is very very rare presentation of usual epigastric hernia. We presented here a 72 years old man with an unusual presentation of very large voluminous mass in the anterior abdominal wall (epigastric hernia) of more than 30 years duration. Surgery revealed an epigastric hernia presenting as an inter-parietal hernia. The hernial sac contained omentum, transverse colon, part of stomach and the patient presented with acute obstruction. No similar case has been found in the medical literature.
Keywords: Epigastric, Interparietal hernia, obstruction, Omentum, transverse colon,
[1] Mark A. Malangoni, MD Michael J. Rosen, MD; Townsend: Sabiston Textbook of Surgery, 18th ed. CHAPTER 44 – Hernias
[2] Badoe E.A., Archampong E.Q., da Rocha-Afodu J.T. Principles and Practice of Surgery. 3rd ed. Ghana Publishing Corporation; Accra, Ghana: 2000. Hernia. p. 482–502.
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