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| Paper Type | : | Research Paper |
| Title | : | Controlled Release Tablets of Zileuton by Using Gum Based and Hpmc Polymers |
| Country | : | India |
| Authors | : | Ayesha Haseena || Asfia Kauser || Faheem Unnisa Begum || Taiyaba Fatima |
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: | 10.9790/3008-1203030110  |
Abstract: The aim of the present study was to develop Controlled release formulation of Zileuton to maintain constant therapeutic levels of the drug for over 12 hrs. Sodium alginate, Guar gum and HPMC K15M were employed as polymers. Zileuton dose was fixed as 300 mg. Polymers were used in the concentration of 100, 200 and 300 mg concentration. All the formulations were passed various physicochemical evaluation parameters and they were found to be within limits. Whereas from the dissolution studies it was evident that the formulation (F6) showed better and desired drug release pattern i.e., 98.86 % in 12 hours. It contains the natural polymer Zileuton as controlled release material. It followed zero order release kinetics mechanism.
Keywords: Zileuton, Guar gum , HPMC K15 M, Sodium alginate and controlled release tablets.
[1]. 1Nokhodchi, Shaista Raja, Priya Patel, Kofi Asare-Addo. The Role Of Oral Controlled Release Matrix Tablets In Drug Delivery Systems. Bioimpacts. 2(4);175-187:2012.
[2]. 39Amir Badshah, FazalSubhan, Khalid Rauf, Nadeem Irfan Bukhari, Zia Ahmed. Development Of Controlled-Release Matrix Tablet Of Resperidone: Influence OfMethocel®-And Ethocel®-Based Novel Polymeric Blend On In-Vitro Drug Release And Bioavailability. AAPS Pharm. sci.tech. 12(2);525-533:2011.
[3]. Anil K. Anal. Time-Controlled Pulsatile Delivery Systems For Bioactive Compounds. Recent Patents On Drug Delivery & Formulation. 1;73-79:2007.
[4]. Anne B Chang, John G Widdicombe. Cough throughout life: children, adults and the senile. Pulmonary Pharmacology & Therapeutics. 20;371-382:2007.
[5]. Ansel HC, Allen LV, Popvich NG. Pharmaceutical Dosage Forms And Drug Delivery System. 2000;7th :229-243.
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| Paper Type | : | Research Paper |
| Title | : | Improving Problem-Solving Ability Through Culture-Based Learning Model Of Tudang Sipulung |
| Country | : | Indonesia |
| Authors | : | Evi Ristiana || Mohamad Amin || Siti Zubaidah || Mimien Heni Irawati Al Muhdar |
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: | 10.9790/3008-1203031114 |
Abstract: This study aims to describe the problem solving ability of students in the subjects of General Biology. Learning model used culture-based prawn shrimp. Subjects in this study are students semester 1 majoring in biology education academic year 2014-2015 Muhammadiyah University of Makassar and the object of research is the ability problem-solving and student responses with a culture-based model of shrimp ponds. Data analysis techniques used are average, percentage and likert scale. The results of this study indicate that based on the average student problem solving ability after using the BTS model is 84.4 with excellent qualification..............
Keywords: Problem Solving, Culture-Based Learning Model of Tudang Sipulung.
[1]. Susanto, P. 2010. Pengembangan Strategi Pembelajaran Biologi; Bahan Ajar Untuk Pendidikan Profesi Guru. Malang; Jurusan Biologi FMIPA Universitas Negeri Malang
[2]. Gagne, R.M. 1985. The Condition of Learning and Theory of Instruction. New York: Holt Rineehart and Winston.
[3]. Dwiyogo, W.D. 2008b. Pembelajaran Visioner. Bekasi: Media Visioner.
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| Paper Type | : | Research Paper |
| Title | : | Cauda Equina Syndrome: A Case Report |
| Country | : | India |
| Authors | : | T. Hari keerthana || Vijay Jagadeesh Kakimani || N. Surendra Reddy || Kali Chandrasekhar || D. Ranganayakulu |
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: | 10.9790/3008-1203031516 |
Abstract: Cauda equina syndrome (CES) is a rare syndrome which is characterized by low back pain, unilateral or bilateral sciatica, motor weakness of lower extremities, saddle anesthesia, bowel and bladder dysfunction and occasionally paraplegia—resulting from compression of the cauda equina. It can be caused by herniated disc, tumor, infection, fracture, or narrowing of spinal cord. It can be described in two forms based on the onset of signs and symptoms. if symptoms appear within 24hours then it is acute in onset and if patient develop symptoms after several weeks or months then it is gradual in onset.............
Keywords: CES, bladder dysfunction, nerve damage, MRI, surgical decompression
[1]. Alex Gitelman, MD, Shuriz Hishmeh, MD, Brian N. Morelli, MD, Samuel A. Joseph, Jr., MD,Andrew Casden, MD, Paul Kuflik, MD, Michael Neuwirth, MD, and Mark Stephen, MD; Cauda Equina Syndrome: A Comprehensive Review; The American Journal of Orthopedics.
[2]. ER Crowther, BA, DC; Slow onset cauda equina syndrome:a case report; 0008-3194/93/203-209/$2.00/©JCCA 1993.
[3]. http://orthoinfo.aaos.org/topic.cfm?topic=a00362.
[4]. http://www.spine-health.com/conditions/lower-back-pain/treatments-cauda-equina-syndrome.
[5]. Balaji Douraiswami, M.S. (Ortho), D.N.B. (Ortho), M.Ch. (Orth), Kumanan Muthuswamy, M.S. (Ortho), Dilip Kumar Naidu, M.S. (Ortho), M.Ch. (Orth), Sriram Thanigai, M.S. (Ortho), and Vijay Anand, M.S. (Ortho); Indeterminate cauda equina syndrome: A case report; 2016 Jan-Mar; 7(1): 50–54. Published online 2015 Jul 18..
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| Paper Type | : | Research Paper |
| Title | : | Effect of Methods of Hydrolysis on the Composition of Prosopis Africana seed Hydrolysates |
| Country | : | Nigeria. |
| Authors | : | Onah, AI || Okore, VC |
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: | 10.9790/3008-1203031720 |
Abstract: Variations in plant or animal species, climatic conditions as well as processing methods affects the reproducibility, quality and quantity of natural or industrial raw materials. In the present study, Prosopis africana seed was hydrolysed using two distinct methods. In a separate study, the hydrolysates were found to be good sources of peptone for microbial cultures. The proximate analyses of contents of hydrolysates obtained from enzyme-hydrolysed or acid-hydrolysed seeds were determined. The seeds obtained from a local market were thoroughly cleaned and boiled until the seed coats were softened............
Keywords: Prosopis africana seed hydrolysates, papain, Hydrochloric acid
[1]. Keay RWJ, Onochie CFA and Stanfield DP 1964. The Nigeria tree, Vol II. Federal Forestry Research, Ibadan, Nigeria, pp 113-114.
[2]. Sanni AE and Lindberg AM. 1993. Fatty acid composition of Prosopis africana and its fermented products
[3]. "Okpehe".Food Chemistry Microbiology Technology 15: 89-90
[4]. Gberikon GM., Agbulu CO and Yaji ME. 2015. Nutritional composition of fermented Prosopis africana soup condiment with and without inocula. International Journal of Current Microbiology and Applied Sciences 4(2): 166-171.
[5]. Adenike AOO, Mopelola O and Ayansina ADV. 2007. Microbial studies and Biochemical characteristics of controlled fermented Afiyo- a Nigerian fermented Food Condiment from Prosopis africana (Gull and Perr.) Taub. Park Journal of Nutrition 6:620-627...
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| Paper Type | : | Research Paper |
| Title | : | A Study to Predict the Conversion of Laparoscopic To Open Cholecystectomy Using Ultrasound Score |
| Country | : | India |
| Authors | : | Manivannan .R, Jagadeesh |
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: | 10.9790/3008-1203032128 |
Abstract: The aim of this study is to preoperatively predict the conversion of Laparoscopic to open cholecystectomy by using ultrasound scoring the following factors: GB Status, GB Wall thickness, No of stones, Pericholecystic collection , Stone size............
Keywords: .....
[1]. Murphy JB. The diagnosis of gallstones. Am Med News 1903:825–833.
[2]. Litynski GS. Erich Muhe and the rejection of laparoscopic cholecystectomy (1985): a surgeon ahead of his time. JSLS : Journal of the Society of Laparoendoscopic Surgeons/Society of Laparoendoscopic Surgeons. 1998;2:341–6
[3]. Gutt CN, Encke J, Koninger J, Harnoss JC, Weigand K, Kipfmuller K, et al. Acute cholecystitis: early versus delayed cholecystectomy, a multicenter randomized trial (ACDC study, NCT00447304). Ann Surg. 2013;258:385–93. Takada T, Strasberg SM, Solomkin JS, Pitt HA, Gomi H, Yoshida M, et al. TG13: Updated Tokyo Guidelines for the management of acute cholangitis and cholecystitis. J Hepatobiliary Pancreat Sci. 2013;20:1–7.
[4]. Committee AT, Adler DG, Conway JD, Farraye FA, Kantsevoy SV, Kaul V, et al. Biliary and pancreatic stone extraction devices. Gastrointest Endosc. 2009;70:603–9
[5]. Yokoe M, Takada T, Strasberg SM, Solomkin JS, Mayumi T, Gomi H, et al. TG13 diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 2013;20:35–46.
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| Paper Type | : | Research Paper |
| Title | : | Biosynthesis of Silver Nanoparticles by Food-Origin E. coli and Candida Species and Testing Its Antimicrobial Activity against Pathogenic Bacteria and Fungi |
| Country | : | Iraq. |
| Authors | : | Marwa Hameed. M. Al-Khafaji || Sura Muayad Abdul Majeed || Rabaab Qzar Basi |
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: | 10.9790/3008-1203032934 |
Abstract: Due to the growing demand to improve an environmentally friendly, nonhazardous and cost-effective technology as a biocide to control the drug-resistant microorganism, thus in the present study; food-origin Escherichia coli, Candida zeylanoides and C. krusei were used for the biosynthesis of silver nanoparticles. The biosynthesis of silver nanoparticles was monitored upon the colour change of the reaction mixture by ultraviolet-visible spectroscopy. Furthermore, the product was explored by Atomic Force Microscopy..........
Keywords: Biosynthesis, Silver nanoparticles, C. zeylanoides, C. krusei, E. coli, Atomic Force Microscopy
[1]. Xue, B.; He, D.; Gao, S.; Wang, D.; Yokoyama, K. and Wang, L. (2016). Biosynthesis of silver nanoparticles by the fungus Arthrodermafulvum and its antifungal activity against genera of Candida, Aspergillus and Fusarium. International Journal of Nanomedicine,11: 1899-1906.
[2]. Singh, P.; Kim, Y. J.; Singh, H.; Wang, C.; Hwang, K. H.; Farh, M. and Yang, D.C. (2015). Biosynthesis, characterization, and antimicrobial applications of silver nanoparticles. International Journal of Nanomedicine, 10: 2567–2577.
[3]. Zhang, X., et al., (2011). Synthesis of nanoparticles by microorganisms and their application in enhancing microbiological reaction rates. Chemosphere. 82(4): p. 489-494.
[4]. Divya, K.; Kurian, L.C.;Vijayan, S. andJisha, M.S.(2016). Green synthesis of silver nanoparticles by Escherichia coli : Analysis of antibacterial activity. J. Water Environ. Nanotechnol. 1(1): 63-74 .
[5]. Mann, S.(2001). Biomineralization: principles and concepts in bioinorganic materials chemistry. Vol. 5.Oxford University Press...
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| Paper Type | : | Research Paper |
| Title | : | Occurrence Of Nematodes And Trematode Cercariae In Lymnea Species Of Danmadahun Part Of Jakara Dam, Kano State, Nigeria |
| Country | : | Nigeria |
| Authors | : | Rabi Suraj Duwa |
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: | 10.9790/3008-1203033539 |
Abstract: This paper reports the occurrence of nematodes and trematode cercariae in Lymnea species of one part of Danmadahun in Jakara dam, Kano state, Nigeria. This study was initially carried out between October to January 2017 to determine the types of trematode cercariae in freshwater snails in the water body. Freshwater snails were collected from the accessible sites on Danmadahun part of Jakara dam and placed individually in compartmented petridishes for cercarial shedding.............
Keywords: Cercariae, Danmadahun, Jakara dam, Lymnea species, Nematodes
[1]. Agbolade, OM., Gledhil, T., Fajebe, OT., Abolade, OM. and Olateju, TM., (2007). Population, seasonal abundance, Dockovdia oruensis infection and other parasites of Potadoma moerchi in southwestern Nigeria. African Journal of Biotechnology, vol. 6, no. 6, p. 826-830.
[2]. Alan Buse (1974) The Relationship of Chaetogaster limnaei (Oligochaeta: Naididae) with a Variety of Gastropod Species The Journal of Animal Ecology, Vol. 43, No. 3 pp. 821-837 Published by: British Ecological Society
[3]. Bem, A.A, Antsa, R.T., Orpin, J.B, Bem, S.L, And Amua, Q.M (2014) Root-Knot Nematode (Meloidogyne Species) Distribution in Some Tomato Fields in Makurdi IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS). Volume 9, Issue 4 Ver. II PP 143-146
[4]. Betterton, C., Ndifon, G.T., Tan, R.M., (1988b). Schistosomiasis in Kano State, Nigeria, II. Field studies on aestivation in Bulinus rohlfsi (Clessin) and B. globosus (Morelet) and their susceptibility to local strains of Schistosoma haematobium (Bilharz). Annals of Tropical Medicine and Parasitology 82: 571–579.
[5]. Duwa S R (2017b) Emergence of New Snail Species and Cercariae on Jakara Dam
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| Paper Type | : | Research Paper |
| Title | : | Traditional Medicinal Plants Used By Tigrigna Ethnic Group In Central Region Of Eritrea |
| Country | : | Eritrea |
| Authors | : | Biniam Yemane || Mehari Andebrhan || Kunduru Surender Reddy |
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: | 10.9790/3008-1203034046 |
Abstract: An ethnobotanical study was conducted from October 2015 to April 2016 to investigate the uses of medicinal plants by the Tigrigna people of 15 villages and towns of Central region of Eritrea such as Asmara, Serejaka, Himbirti, Ebardea, Kitmowlie, Tseada-krstian, Nefasit, Embaderho,Embeyto, Adi-Hawesha, Tsazega,AdiTeclay, Adi-guadad, Selae-daero andAdemneger.Information was gathered from 50 people: 19 female and 31 males, using semi-structured questionnaire of which 22 are local healers. The informants, except the healers, were selected randomly and no appointment was made prior to the visits............
Keywords: Conservation, Ethnobotany, Tigrigna, Healthcare, IK, Medicinal plant
[1]. BayafersTamene (2000). A Floristic Analysis and Ethno botanical Study of the Semi Wet land of Cheffa Area, South Wello, Ethiopia.M. Sc. Thesis, Addis Ababa University.
[2]. Biniamyemaneand GhebrehiwetMedhanie (2014).Ethnobotanical study of medicinal plants in sub zobaDebarwa, zobaDebub, Eritrea. Eritrea journal of Science and engineering 2 (1):63-97.
[3]. Central statistics unit of the Maekel region (2016).Eritrea, North East Africa.
[4]. Cotton, C. M. (1996). Ethnobotany: Principles and Applications. John Wiley and Sons
[5]. Ltd. Chichister, England, pp. 347.
[6]. Cunningham, A. B. (1996). People, park and plant use recommendation for multiple uses
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| Paper Type | : | Research Paper |
| Title | : | Development of functional nourishing cream using fulvic acid |
| Country | : | Korea. |
| Authors | : | ByungWan Jo || JunHo Jo || Yunsung Lee1 |
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: | 10.9790/3008-1203034758 |
Abstract: Fulvic acid is a natural material contained within soil that contains an ample amount of minerals and various functionalities such as antioxidation, currently making it a popular choice as a raw material for food, medicine and cosmetic products. Therefore, the research is to develop functional cosmetics for the prevention of skin aging by using fulvic acid, a natural humic substance that is effective in improving whitening and wrinkle. However, adenosine, edelweiss-cultured natural extracts, Niacinamide, Bio-AHP 500H, etc. are mixed in the cream to minimize the effective chelate reaction............
Keywords: Fulvic Acid, Functional Nourishing Cream, Cosmetic.
[1]. Carmen Donisa, Raluca Mocanu, and Eiliv Steinnesl (2003) Distribution of some major and minor elements between fulvic and humic acid fractions in natural soils. Science direct. Geoderma 111, 75-84.
[2]. Syuntaro Hiradate, Takuya Yonezawa and Hiroshi Takesako (2006) Isolation and purification of hydrophilic fulvic acids by precipitation. Science direct. Geoderma 132: 196-205.
[3]. Daqing Gan, Shaban, I. Kotob, and Daman, S. Walia (2007) Evaluation of a spectrophotometric method for practical and cost effective quantification of fulvic acid. Annals of Environmental Science. 1: 11-15.
[4]. Rauthan, B. S. and M. Schnitzer (1981) Effects of a soil fulvic acid on the growth and nutrient content of cucmber (cucumis sativus) plants. Plant Soil. 63: 491-495.
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| Paper Type | : | Research Paper |
| Title | : | Iodometric Determination of the Ascorbic Acid (Vitamin C) content of mango and tomato consumed in Mettu Town Ilu Abba Bora Zone, Oromia Ethiopia |
| Country | : | Ethiopia |
| Authors | : | Kebena Gebeyehu Motora |
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: | 10.9790/3008-1203035961 |
Abstract: The objective of this study was to determine the ascorbic Acid (Vitamin C) Content of mango and tomato fruit Consumed in Mettu Town of Ethiopia. Representative commercial fruits of mango and tomato were purchased randomly from local market found in Mettu Town which is found in Oromia regional state of Ethiopia and brought to Chemistry Department in Mettu University and preserved in Refrigerator. The fruit samples were first washed with water; thejuice from each fruit was squeezed out, and filtered. Then, the obtained juice was centrifuged until a clear sample was obtained, which was subsequently analyzed for Ascorbic acid content of fresh fruit juices by volumetric method...........
Keywords: Ascorbic acid, friuts, Iodometric determination
[1]. K.J. Thurlor. and I.D. Lumley. (1989). Fruit classification. International Journal of Plant Sciences. 13(5) 85-91.
[2]. J.E. Alibone. (2000). Livestock feeds and feeding. Nutrition Abstracts and Reviews. 72(12) 651-659.
[3]. A. Ralph. and D.A. Bender. (2000). Vitamin C, Journal of Human Nutrition and Dietetics. 2(2) 75-81.
[4]. D.E. Okwu and I.N. Emenike. (2007). Nutritive value and mineral content of different varieties of citrus fruits. Journal of Food Technology. 5(2) 105-108.
[5]. G.D.P. Roger. (2002). Encyclopedia of medicinal plants, education and healthy library. Editorial Safeliz S.L. Spalm. 1,153-154; 265-267.
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| Paper Type | : | Research Paper |
| Title | : | Action of Melatonin on Severe Acute Liver Failure in Rats |
| Country | : | Brazil. |
| Authors | : | Jeferson de Oliveira Salvi || Elizângela Gonçalves Schemitt || Josieli Raskopf Colares || Renata Minuzzo Hartmann || Cláudio Augusto Marroni || Norma Anair Possa Marroni |
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: | 10.9790/3008-1203036275 |
Abstract: Severe acute liver failure (ALF) manifests itself as a rare syndrome, with multiple etiologies for similar clinical conditions. Melatonin (MLT) is a lipophilic indolamine that is synthesized in the pineal gland from serotonin. This study was designed to evaluate hepatic changes resulting from the thioacetamide-induced ALF model, as well as the effects of MLT treatment in male Wistar rats (n = 56) in 24- and 48-h experiments. The results indicate a hepatoprotective effect of MLT, with no difference between the studied times, and increased animal survival.
Keywords: N-acetyl-5- methoxytryptamine, antioxidant, oxidative stress, liver failure
[1] Panackel C, Thomas R, Sebastian B, Mathai SK. Recent advances in management of acute liver failure. Indian J Critic Care. 2015;19(1): 27-33.
[2] Soultati A, Dourakis S. Pathogenesis of Fulminant Hepatic Failure. Ann Gastroenterol, North America. 2007;19(4): 313-24.
[3] Romero M, Palmer SL, Kahn JA, Ihde L, Lin LM, Kosco A, et al. Imaging appearance in acute liver failure: correlation with clinical and pathology findings. Dig Dis Sci. 2014;59(8): 1987-95.
[4] Lee WM, Sstravitz RT, Larson AM. Introduction to the revised American association for the study of liver diseases position paper on acute liver failure. Hepatology. 2012;55: 965-7. [5] Bernal W, Wendon J. Acute Liver Failure. N Engl J Med. 2013; 369:2525-34.