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Abstract: Objective: In this study the potency of antibacterial activities of crude organic solvent extracts ethyl acetate, dichloromethane, and methanol extracts of Knoxia corymbosa were tested on bacterial pathogens Escherichia coli, Klebsiella pneumonia, Staphylococcus aureus, Streptococcus pneumonia, Bacillus subtilis and the potency of antifungal activities of crude organic solvent extracts ethyl acetate and methanol extracts were tested on fungal pathogens Aspergillus niger and Candida albicans
Keywords: Anti-bacterial activity, Anti-fungal activity, Potato dextrose agar (PDA), Streptomycin sulphate
[1]. Studies on the Chemical Constituents of Knoxia Corymbosa YB Wang et al. Yao Xue Xue Bao 39 (6), 439-441.( 6) 2004.
[2]. Y. B. Wang, J. X. Pu, H. Y. Ren et al., "New acetylated flavonolglycosides from Knoxia corymbosa," Chinese Chemical Letters, vol. 14, no. 12, pp. 1268–1270, 200
[3]. Das S, Bhattacharya AK (1969). Chemical investigations on Knoxia corymbosa. J. Indian Chem. Soc. 1: 301-02.
[4]. Je-Chiuan Ye1, Wei-Chun Chang 2, Dennis Jine-Yuan Hsieh3 and Meen-Woon Hsiao Extraction and analysis of β-sitosterol in HerbalMedicines Journal of Medicinal Plants Research Vol. 4(7), pp. 522-527, 4 April, 2010
[5]. Feng Zhao, Shuai Zhao, Jing-Tian Han, Yuan-Fang Wang, Ya-Nan Wang, Chun- Hua Antiviral anthraquinones from the roots of Knoxia valerianoides Photochemistry LettersVolume 11, March 2015, Pages 57–60..
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Paper Type | : | Research Paper |
Title | : | Understanding Embryonic Stem Cell Pluripotency Through Its Key Players |
Country | : | India |
Authors | : | Rekha Govindan |
: | 10.9790/3008-1203050512 |
Abstract: Certain transcription factors, cofactors, chromatin regulators are identified as the key players in establishing the embryonic stem cell ground state. The activation and silencing of genes in response to potency and lineage development act as the regulatory circuits. Insights into these regulatory circuitory have uncovered fundamental genetic and epigenetic mechanisms that control gene expressions to maintain the ground state. At one end of the circuit are the core transcription factors that self regulate their own gene expression. These factors further activate transcription of genes involved in pluripotency and contribute to the arrest of expression of lineage specific genes. The core transcription factors mediate binding of the enhancers with signaling factors there by extending the circuit to communicate...........
Keywords: Stem cells, ground state, gene circuits, signaling molecules, epigenetic influences
[1]. Anton R, Kestler HA and Kuhl M. (2007). β-Catenin signaling contributes to stemness and regulates early differentiation in murine embryonic stem cells. FEBS Lett. 581, 5247–5254.
[2]. Boyer LA, Lee TI, Cole MF, Johnstone SE, Levine SS, Zucker JP, Guenther MG, Kumar RM, Murray HL, Jenner RG, Gifford DK, Melton DA, Jaenisch R and Young RA. (2005). Core transcriptional regulatory circuitry in human embryonic stem cells. Cell. 122, 947–956.
[3]. Chambers I, Colby D, Robertson M, Nichols J Lee, Tweedie S and Smith, A. (2003). Functional Expression Cloning of Nanog, a Pluripotency Sustaining Factor in Embryonic Stem Cells. Cell. 113, 643–655.
[4]. Chambers I, Silva J, Colby D, Nichols J, Nijmeijer B, Robertson M, Vrana J, Jones K, Grotewold L and Smith A. (2007). Nanog safeguards pluripotency and mediates germline development. Nature. 450, 1230–1234.
[5]. Fong YW, Inouye C, Yamaguchi T, Cattoglio C, Grubisic I and Tjian R. (2011). A DNA repair complex functions as an Oct4/Sox2 coactivator in embryonic stem cells. Cell. 147, 120–131.
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Abstract: Samia ricini, commonly known as eri silk worm is a domesticated, multivoltine, polyphagous silkworm species which have several morphotypes having distinct morphological differences. This silkworm species is cultured in different regions of North-eastern states specially in Assam. In addition to twenty six different ecoraces, six morphologically distinct strains of Samia ricini have been identified on the basis of larval markings and colour, they are Yellow plain (YP), Yellow spotted(YS), Yellow Zebra(YZ) and Greenish blue plain(GBP), Greenish blue spotted(GBS), Greenish blue zebra(GBZ).The present study was conducted with the aim to evaluate the rearing performance of these six strains of eri silk worm in four different seasons. To achieve this goal Fecundity........
Keywords: Strains, ecoraces, fecundity, hatching, Effective rate of rearing
[1]. Chakravorty, R. and Neog, K.(2006) . Food plants of eri silkworm (Samia ricini Donovan) their rearing performance and prospects for exploitation. Abst. of national workshop on eri food plants. Oct.11-12. pp. 1-27.
[2]. Debraj, Y., Sarmah, M.C., Dutta, R.N., Singh, L.S., Das, P.K. and Benchamin, K.V. (2001) Field trail of elite crosses of eri silkworm, philosamia ricini, Hutt, Indian Silk, 40 (2), 15-16.
[3]. Nagaraju, J. and Goldsmith, M.R. (2002) Silkworm genomics-progress prospects. Curr. Sci.83,415-425.
[4]. Rahmathulla,V.K. and Hiromani, M.S.(2013)Influence of temperature and humidity on growth and development of silk gland of a bivoltine silkworm hybrid. Irnian journal of Entomology 3,24-29.
[5]. Ray, P.P., Rao T.V. and Dash,P. (2010) Comparative studies on rearing performance of some ecoraces of erisilkworm (Philosamia ricini H) in different seasons.
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Abstract: The evaluation of microorganisms present in indoors has become necessary, as how safe the air in our surrounding environment where we spent time is fundamental to our wellbeing. Hence, this study was aimed at assessing the indoor air quality of a private university in Benin City using the settle plate air sampling technique with sampling done morning and evening, once in succession for two weeks. The estimated concentration range of bacterial aerosols in the indoor environments was 7 – 440 cfu/m3 and 4 – 90cfu/m3 for week 1 morning and evening sampling respectively, and 72 – 180 cfu/m3 and 8 - 75 cfu/m3 for week 2 morning and evening sampling respectively...........
Keywords: Indoor air, sample, morning, evening, Staphylococcus aureus
[1]. Awosika, S. A., Olajubu, F. A. and Amusa, N. A. (2012).Microbiological assessment ofindoor air of a teaching hospital in Nigeria.Asian Pacific Journal of Tropical Biomedicine2(6): 465 - 468.
[2]. Chessbrough, M. (1991).Medical laboratory manual for tropical countries. Cambridge University Press UK Pp508-511.
[3]. Dumała, S. M. and Dudzińska, M. R. (2013).Microbiological Indoor Air Quality in Polish Schools.Annual Set The Environment Protection 15: 231–244.
[4]. Graudenz, G. S., Oliveira, C. H., Tribess, A., Mendes, C. Jr., Latorre, M. R. and Kalil, J. (2005). Association of air conditioning with respiratory symptoms in office workers in tropical climate. Indoor Air15: 62-66.
[5]. Hayleeyesus, S. F. and Manaye, A. M. (2014).Microbiological Quality of Indoor Air in University Libraries'..Asian Pacific Journal of Tropical Biomedicine. 4(Supplementary 1): S312-S317
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Paper Type | : | Research Paper |
Title | : | A Chack List of Penaeid Prawns Found In Indian Water with Their Distribution |
Country | : | India |
Authors | : | Angsuman Chanda |
: | 10.9790/3008-1203052631 |
Abstract: Present study is an attempt to up to date the taxonomic information of prawns found in Indian water under family Penaeidae Rafinesque – Schmaltz, 1815. Species composition and their distribution in Indian water is the main part of the work. Family Penaeidae is represented by 25 genera of which 17 genera and 78 species has been recorded from Indian water.
Keywords: Taxonomy, Penaeidae, Genera, Species, Distribution.
[1]. Alcock, A. 1901. A descriptive catalogue of the Indian deep-sea Crustacea Decapoda Macrura and Anomala, in the Indian Museum. Being a revised account of the deep-sea species collected by the Rural Indian marine survey ship "Investigator":1-286 Calcutta: Indian Museum.
[2]. Alcock, A. 1905. A revision of the "Genus" Peneus, with diagnoses of some new species and varieties. Ann. Mag. nat. Hist., (7) 16: 508-532.
[3]. Alcock, A. 1906. Catalogue of the Indian Decapod Crustacea in the collection of the Indian Museum. Part III. Macrura. Fasciculus I. The prawns of the Peneus group. Indian Museum, Calcutta: 1-55.
[4]. Chanda, A. 2016. Diagnosis of genera found in India under family Penaeidae Rafinesque – Schmaltz, 1815. LAP LAMBART Academic Publishing, Germany; p, 93. ISBN: 978-3-659-83468-4.
[5]. Chanda, A. (2016). A Study on Newly Described Genera Alcockpenaeopsis, Batepenaeopsis, Helleropenaeopsis, Kishinouyepenaeopsis and Parapenaeopsis from Indian Water. Poult Fish Wildl Sci, 4: 147. Doi:10.4172/2375-446X.1000147
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Abstract:Urinary tract infection is one among the most commonly diagnosed infection of childhood. Frequent unwanted unwarranted usage of antibiotics does more harm. Its important to know the sensitivity pattern in the community. Method: A total of 75 children were included in the study. Culture and sensitivity patterns were checked. Satististical analysis was done on frequency and mean. Results: More of females were found in the study. E.coli was the most common organism isolated. Culture and sensitivity test were done only for few patients. The most frequent empirical antibiotic used was ceftriaxone and cefixime.............
[1]. Palak Gupta1 , Jharna Mandal2 , Sriram Krishnamurthy3 , Deepak Barathi4 & Nandini Pandit. profile of urinary tract infections in paediatric patients. Indian J Med Res 141, April 2015, pp 473-477 [2]. Salvatore S, Salvatore S, Cattoni E, Siesto G, Serati M, Sorice P, Torella M (June 2011). "Urinary tract infections in women.". European journal of obstetrics, gynecology, and reproductive biology. 156 (2): 131–6.doi:10.1016/j.ejogrb.2011.01.028. PMID 21349630
[3]. Derese B, Kedir H, Teklemariam Z, Weldegebreal F, Balakrishnan S. Bacterial profile of urinary tract infection and antimicrobial susceptibility pattern amongpregnant women attending at Antenatal Clinic in Dil Chora Referral Hospital, Dire Dawa, Eastern Ethiopia. Ther Clin Risk Manag. 2016 Feb 18;12:251-60. doi:10.2147/TCRM.S99831. eCollection 2016. PubMed PMID: 26937197; PubMed Central PMCID: PMC4762443.
[4]. European Association of Urology (UAE). Guidelines on urological infections. Grabe M, Bjerklund-johansen TE, Botto H, Wullt B, Cek M, Naber KG, et al. Arnhem, The Netherlands: UAE; 2013. p. 42-9.
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Abstract: Plaque disruption exposes thrombogenic substances that may produce an extensive thrombus in the infarct-related artery. The precursor of BNP and N-terminal pro – Brain Natriuretic Peptide (NT-proBNP) is a pre-pro hormone BNP, The prohormone is released during homodynamic stress from the left and right cardiac ventricle in response to ventricular volume expansion and pressure overload. Recent data suggest that left ventricular end diastolic wall stress and wall stiffness may be the predominate triggers of BNP release. Objective: To determine the level of serum NT-PRO brain natriuretic peptide which marked an increased incidence of cardiovascular events in unselected community-based individuals with many types of acute coronary syndrome admitted to cardiology care unite within 24 hour............
Keywords: B-type natriuretic peptide, Echocardiographic, ACS.
[1] Watanabe I, Tani S, Washio T, et al. Relationship between the plasma levels of brain natriuretic peptide and left ventricular ejection fraction in asymptomatic patients with previous myocardial infarction. Int Heart J. 2005;46:1007–14.
[2] Talwar S, Squire IB, Downie PF, et al. Profile of plasma N-terminal proBNP following acute myocardial infarction; correlation with left ventricular systolic dysfunction. Eur Heart J. 2000;21:1514–21.
[3] Štambuk K, Bulj N, Trbušić M, Krčmar T, Lukinac L. B-type Natriuretic Peptide as Predictor of Heart Failure in Patients with Acute ST Elevation Myocardial Infarction, Single-vessel Disease, and Complete Revascularization: Follow-up Study, newCroat Med J. October 2009;50(5): 449–54.
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Abstract: Pseudomonas aeruginosa is an important infectious agent which causes nosocomial infections in immune-compromised patients, especially among burnt patients. In recent times, it has emerged as a far-flung Multi-Drug Resistant (MDR) pathogen which needs regular and periodic antibiotic susceptibility surveillance. The aim of this study was to isolate and identify MDR-P. aeruginosa from the burn patients held in the burn unit of Chittagong Medical College Hospital (CMCH) for ~2 months under treatment andto determine their antimicrobial resistance pattern for some commonly prescribed antibiotics. P. aeruginosa isolates were recovered from ten random wound swab samples of burnt patients through selective growth on MacConkey and Cetrimide agar media. Selected isolates............
Keywords: Burn wound, Multi-Drug Resistant, Pseudomonas aeruginosa
[1] Eltahawy, A.T., Gram-negative bacilli isolated from patients in intensive care unit: prevalence and antibiotic susceptibility. J Chemother, 1997. 9(6): p. 403-10.
[2] Mousa, H.A., Aerobic, anaerobic and fungal burn wound infections. J Hosp Infect, 1997. 37(4): p. 317-23.
[3] Saffle, J.R., B. Davis, and P. Williams, Recent outcomes in the treatment of burn injury in the United States: a report from the American Burn Association Patient Registry. J Burn Care Rehabil, 1995. 16(3 Pt 1): p. 219-32; discussion 288-9.
[4] Lister, P.D., D.J. Wolter, and N.D. Hanson, Antibacterial-resistant Pseudomonas aeruginosa: clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin Microbiol Rev, 2009. 22(4): p. 582-610.
[5] Rastegar Lari, A.R., R. Alaghehbandan, and L. Akhlaghi, Burn Wound Infections and Antimicrobial Resistance in Tehran, Iran: an Increasing Problem.Annals of Burns and Fire Disasters, 2005. 18(2): p. 68-73.
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Abstract: Acinetobacter baumannii has emerged over the last decade as a significant opportunistic pathogen and primarily associated with hospital-acquired infections. Increasing multidrug resistance pattern of A. baumannii makes it among the most difficult antimicrobial-resistant Gram-negative bacilli to control and treat. The aim of this study was to isolate and identify A. baumannii from clinical samples and to determine their antimicrobial resistance pattern to commonly prescribed drugs to find out Multi-Drug Resistant A. baumannii (MDRAB). Nine different clinical samples were collected from patients admitted to Comilla Medical College Hospital (CoMCH). A. baumannii were isolated and identified based on their growth, physiological, and biochemical characteristics............
Keywords: Acinetobacter baumannii, Multi-Drug Resistant, Nosocomial Infection
[1] Dijkshoorn, L., A. Nemec, and H. Seifert, An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nature Reviews Microbiology, 2007. 5(12): p. 939-951.
[2] Roca, I., et al., The Acinetobacter baumannii oxymoron: commensal hospital dweller turned pan-drug-resistant menace.Analyzing possible intersections in the resistome among human, animal and environment matrices, 2015: p. 40.
[3] Lockhart, S.R., et al., Antimicrobial resistance among Gram-negative bacilli causing infections in intensive care unit patients in the United States between 1993 and 2004. Journal of clinical microbiology, 2007. 45(10): p. 3352-3359.
[4] Nordmann, P., Acinetobacter baumannii, le pathogène nosocomial par excellence.Pathologiebiologie, 2004. 52(6): p. 301-303.
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Abstract: Chitin is a polysaccharide of animal origin found abundantly in nature and characterized by a fibrous structure. It forms the basis of the main constituent of the outer skeleton of insects and crustaceans like shrimp, crabs and lobster. Chitosan has a broad antimicrobial spectrum to which gram-negative, gram-positive bacteria and fungi are highly susceptible. The activity dependence on polymeric molecular weight (MW) and degree of acetylation (DA) are described. The chitosan minimum inhibitory concentrations (MIC) are summarized from this study. The data indicate that the effectiveness of chitosan varies and is dependent on species of target microorganisms.
Keywords: Shrimp, chitosan, Antimicrobial Effect, polysaccharide
[1] Allan, G G., Fox, J. R., & Kong, N. (1978) A critical evaluation of the potential sources of chitin and chitosan, In R. A. A. Muzzarelli and E. R. Pariser (ed.), Proceedings of the First International Conference on Chitin/Chitosan. MIT Sea Grant Report MITSG, 78(3):64-78.
[2] Chung, Y. C.; Su, Y. P.; Chen, C. C.; Jia, G.; Wang, H. L.; Wu, J. C. G. & Lin, J. G. (2004) Acta Pharmacol. Sinica, 25:932-936.
[3] Coma, V.; Deschamps, A. & Martial-Gros, A. (2003) J. Food Sci., 68:2788-2792.
[4] Cuero, R. G.; Osuji, G. & Washington, A. (1991) Biotechnol. Lett., 13:441-444.
[5] Eaton, P.; Fernandes, J. C.; Pereira, E.; Pintado, M. E. & Malcata, F. X. (2008) Ultramicroscopy, 108:1128-1134
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Abstract: Samanea saman (Albizia saman) is a wide-canopied tree with a large symmetrical crown. It usually reaches a height of 25 m (82 ft) and a diameter of 40 m. The leaves fold in rainy weather and in the evening, hence the name "rain tree" and "five o'clock tree" (Pukul Lima) in Malay. In the present investigation, the bioactive methanolic fraction was subjected to HPTLC and GC-MS analysis. GC- MS analysis revealed the presence of six compounds from the methanolic fraction of the Samanea saman (1) 9,Octadecenoic acid (Z) methyl ester, (2) Dodecanoic acid, 10-methyl, methyl ester, (3) 13- Hexyloxyacylotridec-10-en-2-one, (4) 15-Octadecenoic acid, methyl ester..............
Keywords: Samanea saman (Albizia saman); HPTLC analysis; GC- MS analysis.
[1]. Faisol Ferdous, Khalid Hossain, Md. Rahman, S and Rashid, A., Chemical and Biological investigations of Samanea saman (Jacq.) Merr, Dhaka University. J.Pharm.Sci , 9(2),2010,69-73.
[2]. Ravikumar, A. Rijwana shaik and Yeshwanth, D., Phytochemical evaluation of Delonix Regia and Samanea saman, International Journal of research in Pharmacy and chemistry, 3(4),2013, 5-10.
[3]. Iqbal Azhar, Moht asheemul hasan, M and Ali, M.S., Some biological evaluations on Samanea saman, Pakistan Journal of Pharmacology, 26 (1),2009, 47-53.
[4]. Arul priya, P. Lalitha, P and Hemalatha, S., HPTLC finger print of ethyl acetate extract of Samanea saman (Jacq.) Merr, Asian Journal of Research in Chemistry, 4(2), 2011, 266-269.
[5]. Preethi, S and Mary sarai, A., GC-MS analysis of microwave assisted ethanolic extract of Pithecellobium dulce, Malaya Journal of Biosciences, 1(4), 2014 , 242-247.
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Abstract: The comparative effect of caffeinated and decaffeinated coffee on the histomorphology of the kidney of male albino Wistar rats was investigated. Thirty-five (35) male albino Wistar rats (weighing between 135 - 185g) were grouped into seven (7) groups with 5 rats in each group. Group 1 served as the control while Groups 2 to 7 were the test groups. Caffeinated coffee at doses of 5mg, 10mg and 15mg per kg body weight of rats were administered orally to Groups 2, 3, 4 respectively. 5mg, 10mg, 15mg per kg body weight of decaffeinated coffee were administered orally to Groups 5, 6, 7. After 28 days of administration of the coffee, the animals were sacrificed, kidneys were harvested, fixed, processed and cut at 5 microns, stained using Hematoxylin and Eosin...........
Keywords: Caffeinated Coffee, Decaffeinated Coffee, Kidney, Tubular Necrosis, glomerular inflammation.
[1]. Glodny, B., Unterholzner, V., Taferner, B. (2009). Normal kidney size and its influencing factors.
[2]. Walter, F. (2004). Medical Physiology: A cellular and molecular approach. Elsevier/Saunders.
[3]. Nakajima, K., Hirose, K., Ebata, M., Morita, K., Munakata, H. (2009). Association between habitual coffee consumption and normal or increased estimated glomerular filtration rate in apparently healthy adults. British journal of nutrition, 103:149-152.
[4]. Kotani, K., Sakane, N., Yamada, T., Taniguchi, N. (2010). Association between habitual coffee consumption a nd the estimated
glomerular filtration rate in the general Japanese population: preliminary data regarding c-reactive protein concentration. 48: 1773-1776.
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Abstract: Malaria in pregnancy is one of the leading causes of maternal and child morbidity and mortality worldwide, mainly in high endemic areas. Our study aimed to estimate the prevalence of and to identify the possible risk factors associated with Malaria infection among pregnant women attending to antenatal care at health center in Umtalha village in Gezira State, Sudan. Methods: A cross- sectional facility based study was conducted. A total of 332 pregnant women were selected. A structured questionnaire was used to collect data on socio-demographic characteristics and possible risk factors. Blood was screened for malaria parasite. Results: 42 (12.7%)) of respondents were found.............
Keywords: Malaria, pregnant women, , risk factor, Gezira State, Sudan.
[1] Lopez-Perez M, Pacheco MA, Buritica L, Escalante AA, Herrera S and and Arevalo-Herrera M. Malaria in pregnancy: a passive surveillance study of pregnant women in low transmission areas of Colombia, Latin America. Malaria J. 2016; 15:66
[2] Rijken MJ, Gready R, Boel ME, Poespoprodjo R, Singh N, Syafruddin D, et al. Malaria in pregnancy in the Asia-Pacific region. Lancet Infect Dis.2012; 12:75–88.
[3] Williams J, Njie F, Cairns M, Bojang K, Coulibaly SO, Kayentao K, et al. Non-falciparum malaria infections in pregnant women in West Africa. Malaria J. 2016; 15:53
[4] Brutus L, Santall J, Schenider D, Avila JCand Deloron P. Plasmodium vivax malaria during pregnancy, Bolivia. Emerg Infect Dis. 2013; 19:1605–11.
[5] Sharifi-Mood B. Malaria in Pregnant Women. Int J Infect. 2015; 2(3): e22992.
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Abstract: This study focused on the osmotic fragility of erythrocytes and its indices in rats treated with ethanolic leaf extract of Ageratum conyzoides following the administration of Nigerian Bonnylight crude oil (NBLCO). Twenty female Wistar rats (120-150g body weight) were divided into four groups of five rats each. The rats in group I served as the control group and was oral gavaged 3ml/kg of normal saline; group II gavaged 748.33mg/kg body weight of the extract of A. conyzoides, which was 20% of the LD50 (3741.66mg/kg). Group III was gavaged 3ml/kg body weight of NBLCO. This dose was calculated as 20% of the lethal dose of 14.14 ml/kg. Group IV animals were gavaged 748.33mg/kg body weight of the extract of A. conyzoides, and 3ml/kg body weight of NBLCO. In all cases, doses were applied daily for 31 days according to animal's most recent body weight. The results showed that NBLCO significantly increased osmotic............
Keywords: Crude Oil, Erythrocyte Membrane, Erythrocyte Haemolysis, Osmotic Fragility, Ageratum conyzoides
[1]. Ali, M. S. M. and Kadaru, A. G. M., 2005. In vitro processing of donor blood with sulphadoxine-pyrimethamine for eradication of transfusion-induced malaria. American Journal of Tropical Medicine and Hygiene,73(6): 1119-1123.
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