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| Paper Type | : | Research Paper |
| Title | : | A Study On Effects Of The Most Commonly Used Chemotherapeutic Drugs On Haematological Parametres |
| Country | : | India |
| Authors | : | PV.Akshaya || Mounika R || Reddy SV || chaudhary GP || Srinivasan.R || Sharma S |
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: | 10.9790/3008-1204020110  |
Abstract: Cancer is a group of more than hundred diseases that are characterized by uncontrolled cellular growth, local tissue invasion, and distant metastasis. To treat the cancer there are many types of treatments that includes Surgery, Radiation therapy, Chemotherapy.Data collection form was designed and piloted to collect, document and analyse the data. The data collection form had provision for collecting key information like demographics (UHID, age, gender, weight), past medical history.............
Keywords: Chemotherapy, Haematology, Adverse drug reaction, Anaemia and Cancer.
[1] What Is Cancer? - National Cancer Institute.avilable online at
[2] http://www.cancer.gov/about-cancer/what-is-cancer (accessed on 21.4.2016 ,at 2:40pm)
[3] Cisplatin | Cancer Research UK.www.cancerresearchuk.org › ... › Treatment › Cancer drugs http://www.cancerresearchuk.org/about-cancer/cancers-in-general/treatment/cancer-drugs/cisplatin#general (accessed on 21.04.2016, at 2:50pm).
[4] Paclitaxel (Taxol) | Cancer Research UK.www.cancerresearchuk.org › ... › Treatment › Cancer drugs
[5] http://www.cancerresearchuk.org/about-cancer/cancers-in-general/treatment/cancer-drugs/paclitaxel (accesed on 21.04.2016, at 2:55pm)
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| Paper Type | : | Research Paper |
| Title | : | 2D-QSAR analysis on some 8-methoxy quinoline derivatives as H37RV (MTB) inhibitors with comparison of different model |
| Country | : | India |
| Authors | : | Kalpana Prajapati || Satkar Prasad || Sailesh Kumar Ghatuary || Anil Sarathe || Gaurab Duby || Reena Sheride |
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: | 10.9790/3008-1204021119 |
Abstract: activity relationship (QSAR) study has been performed on 8-methoxy quinoline based on inhibitors of H37RV (MTB). The compounds in the selected series were characterized by physicochemical and topological descriptors calculated using 2D-QSAR module of VLife MDS software. Correlations between different inhibitory activities and calculated predicted variables were established through employing the multiple linear regression, Stepwise forward-backward method.............
Keywords: Antimycobacterial activity; Antitubercular activity; 8-Methoxyquinolone Carboxylic acids.
[1] Nakajima H. Tuberculosis: A Global Emergency. World Health, 1993; 46: 3.
[2] Dolin P J, Raviglione M D, Kochi A. Global Tuberculosis Incidence and Mortality during 1990-2000. Bull. WHO, 1994; 72:213-
220.
[3] Rouchi A M. Tuberculosis: A Tough Adversary. Chem. Eng.News 1999; 77: 52-69.
[4] Nunn P, Kochi A. A Deadly DuosTB and AIDS. World Health, 1999; 46:7-8.
[5] Raviglione M D, Snider D, E Jr, Kochi A. Global Epidemiology of Tuberculosis: Morbidity and Mortality of a Worldwide
Epidemic. JAMA, 1995; 273: 220-226..
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| Paper Type | : | Research Paper |
| Title | : | Effect of Environmental Factors on Pollen Viability of Tropical Trees in Garhjungle Sacred Forest Of West Bengal, India |
| Country | : | India |
| Authors | : | Ashoke Bhattacharya |
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: | 10.9790/3008-1204022025 |
Abstract: Tropical trees of Garhjungle sacred forest, West Bengal, India may change in pollen viability according to pollinator, flower exposure, and pollen predacious thrips. A pole clipper system was used, and in vitro viability measures, to evaluate relative impact of such factors in six forest tree species. Relative pollen viability was measured with Alexander's stain, or TTC stain for Madhuca indica Gmelin. (Sapotaceae); Buchanania lanzan Spreng. (Anacardiaceae); Pterocarpus marsupium Roxb. (Fabaceae); Alangium lamarckii Thw. (Alangiaceae); Schleichera oleosa (Lour.)............
Keywords: pollen, pollination, thrips, Garhjungle.
[1] Aizen, M., Rovere A. 1995. Does pollen viability decrease with aging? A cross-population examination in Austrocedrus chilensis (Cupressaceae). International J. Plant Science 156, 227-231.
[2] Alexander, M,P. 1969. Differential staining of aborted and non-aborted pollen. Stain Technology 62, 107-112.
[3] Brewbaker, J.L. 1967. The distribution and phylogenetic significance of binucleate and trinucleate pollen grains in the angiosperms. American Journal of Botany 54, 1069-1083.
[4] Dafni, A. 1992. Pollination ecology: A practical approach. Oxford University Press, Oxford.
[5] Dafni, A., Firmage, D. 2000. Pollen viability and longevity: practical, ecological and evolutionary implications. Plant Syst. Evol. 222, 113 – 132.
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| Paper Type | : | Research Paper |
| Title | : | Anti diabetic activity of the stem bark extract and fractions of Faidherbia albida Del. (Mimosaceae) in murine model. |
| Country | : | Nigeria. |
| Authors | : | A.J.Kashimawo || J.A. Kolawole || J.O. Kemelayefa |
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: | 10.9790/3008-1204022630 |
Abstract: Background: In our continued search for potent anti-diabetic compound(s) from plants and natural sources, we tested crude extract and fractions of the stem bark of Faidherbia albida - a plant traditional used in the management of diabetes mellitus in Northern Nigeria, on alloxan induced diabetic rats to obtain the most active fraction. Space and Duration of Study: The study was conducted between November 2016-March 2017 using laboratories of Departments of Pharmaceutical Chemistry and Department of Pharmacology of Niger Delta University..............
Keywords: F.albida, Diabetes mellitus.
[1] Abdalla M, Abdelatif, Mariam Y, Ibhrahim, Mahmoud S. Antidiabetic Effects of Fenugreek
[2] (Trigonella foenum - graecum) Seeds in the Domestic Rabbit (Oryctolagus cuniculus). Res J of
[3] Medicinal Plant 2012; 6: 449-455.
[4] Brownlee M, Cerami A. The biochemistry of the complications of diabetes mellitus. Annual review of biochemistry 1981; 50 (1): 385-432
[5] Doughari JH, Ndakidemi PA, Human IS, Benade S. Antioxidant, antimicrobial and antiverotoxic potentials of extracts of Curtisia dentata. J Ethnopharmacol2012;141: 1041-1050..
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| Paper Type | : | Research Paper |
| Title | : | Phytochemical Analysis of Some Selected Plants and Families in the University Botanic Garden Of Maseno, Kenya |
| Country | : | Kenya. |
| Authors | : | Stephen F. Sikolia || Seline Omondi |
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: | 10.9790/3008-1204023138 |
Abstract: There has scarcely been any attempt to carry out phytochemical analysis on various insitu and ex situ plants conserved at the University Botanic Garden and no research has been done to document the educational and economic values of the garden. Moreover, the rate at which the plant biodiversity is being cleared is alarming, and calls for urgent need of conserving plants of high economic values. It is on the basis of such need that the study was carried out at the University Botanic Garden..............
Keywords: University Botanic Garden of Maseno, Flavonoids, Terpenes, Alkaloids, Steroids and anthraquinones, Medicinal Plants).
[1] BGCI,The Global network. http://www.bgci.org/global/, accessed on 21/06/2011, 2011a.
[2] Rinker,H.B.,The Weight of a Petal: The Value of Botanical Garden.http://www.actionbioscience.org/biodiversity/rinker2.htm (Published by American Institute of Biological Sciences. 2002).
[3] Jeruto, P.,Ethno-Botanical Survey and Propagation of priority medicinal plants in Aldai region of Nandi south district.M.Sc. thesis, Maseno University, Kenya, 2008.
[4] Oldfield, S.,Tackling Invasive Species. BGjournal,8, 2011, 2.
[5] BGCI (2011b). The Global Trees Campaignhttp://www.bgci.org/ourwork/Rhododendron-Red-List, accessed on 21/06/2011, 2011b.
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| Paper Type | : | Research Paper |
| Title | : | Antihyperlipidemic And Glucose Lowering Effect Of Extract Of Bioregulator Treated Okra (Abelmoschus Esculentus L.) Fruits in Triton-Induced Hyperlipidemia Rats |
| Country | : | Nigeria. |
| Authors | : | A.M. Esan || C.O. Olaiya || V. Sameer || K. Elango || S.P. Dhanabal |
|
: | 10.9790/3008-1204023950 |
Abstract: Extracts from okra have been used to alleviate not only hyperglycemia but also hyperlipidemia in diabetic mice induced by alloxan and streptozocin. However, its hypolipidemic activity has not yet been clearly studied. This study was aimed to study the antihyperlipidemic potential of bioregulator treated okra fruit in triton-X induced hyperlipidemic rats. Hyperlipidemia was induced in rats by administration of triton-X (100mg/kg i.p.). After 14 days of induction..............
Keywords: Bioregulator, Carbohydrate enzymes, lipid profiles, Okra, Triton-X.
[1] G.D. Kolovou, K. K. Anagnostopoulou,D. V. Cokkinos,"Pathophysiology of dyslipidaemia in themetabolic syndrome,"Postgraduate Medical Journal 81 (956), 2005, 358–366.
[2] R.M. Krauss, Y.A. Kesaniemi, "Cardiovascular disease and hyperlipidaemia," Current Opinion in Lipidology, 5 (4), 1994, 249–251.
[3] G.S. Hotamisligil, E. Erbay, Nutrient sensing and inflammation in metabolic diseases. Nat Rev Immunol. 8, 2009, 923-34
[4] J.H. Goedecke, J.A. Dave, M.V. Faulenbach, Insulin response in relation to insulin sensitivity: an appropriatebeta-cell response in black South African women. Diabetes Care. 32(5), 2009, 860-65
[5] D. Hayoz, T. Ziegler, Diabetes mellitus and vascular lesions. Metabolism. Curr. Ther. Res., 47,1998, 16-19..
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| Paper Type | : | Research Paper |
| Title | : | Ecological Implications Of The ẟ13c Values of Plant Species Growing in Natural Environment, Greenhouse and Plant Respired Carbon Dioxide (Captured As Carbonate) |
| Country | : | Kenya. |
| Authors | : | Stephen F. Sikolia |
|
: | 10.9790/3008-1204025158 |
Abstract: ẟ13C values have been used to differentiate the C3 plant species from the C4 species. Light isotope (12C) is favoured against the heavier isotope (13C) during the carbon fractionation in plant species. The ẟ13C valuesof terrestrial plant are useful in diverse applications in ecological, forensic, microbial diagnostic, biochemical and other scientific studies. There is variation of the ẟ13C values between the intraspecies grown in the greenhouse under controlled climatic conditions except respired carbon dioxide concentration. Also, ẟ13C values variation exist between interspecies..............
Keywords: ẟ13C values, C3 and C4 plant species, respired carbon dioxide, climatic factors, Ribulose bisphosphate carboxylase, Phosphoenol pyruvate carboxylase, carbon fractionation.
[1] M.M., Bender, Variations in the 13C/12C ratios of plants in relation to the pathway of photosynthetic carbon dioxide fixation. Phytochemistry, 10, 1971, 1239-1244.
[2] H.E. Epstein, W.K. Lauenroth, I.C. Burke and D.P. Coffin, Productivity patterns of C3 and C4 functional types in the U.S. Great Plains. Ecology, 78(3), 1997, 722-731.
[3] S. Sikolia, E. Beck, J.I. Kinyamario, J.C. Onyango and G. Ouma, 13ẟ values of the Centrospermeae and their ecological implications in the semi-arid conditions. International Journal of Botany, 4(4), 2008, 421-429.
[4] B. Cregg and J. Zhang, Carbon discrimination as a tool to screen for improved drought tolerance. Proceedings of the 11th Metropolitan Tree Improvement Alliance (METRIA) Conference held in conjunction with the Landscape Plant Development Center Gresham, Oregon, August 23-24, 2000.
[5] G.D. Farquhar,J.R. Ehleringer and K.T. Hubick, Carbon isotope discrimination and photosynthesis. Annual Review of Plant Physiology and Plant Molecular Biology, 40, 1989, 503-537...
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| Paper Type | : | Research Paper |
| Title | : | A Measure of Haemoglobin Instability in Individuals phenotyped as haemoglobin AC, SC and CC by Acetate Electrophoresis |
| Country | : | Nigeria. |
| Authors | : | Oluboyo B. O || Taiwo M. S || Oluboyo A. O || Olayanju A. O |
|
: | 10.9790/3008-1204025962 |
Abstract: One of the limitations in haemoglobin electrophoresis technique is the inability to distinguish between stable haemoglobin-C and unstable Haemoglobin-E. Haemoglobins A2, C, E and OArab migrate together during cellulose acetate electrophoresis and are often not differentiated by most diagnostic laboratories. This study investigated the instability of phenotyped haemoglobin-C individuals and the possibility of haemoglobin-E individual..............
Keywords: Unstable Haemoglobins, Haemoglobinopathies, phenotype, instability, isopropanol
[1] B. Wild and B. Bain, Investigation of abnormal haemoglobins and thalasaemia, in S. M. Lewis., B. J. Bain., I. Bates, (Eds), Dacie and Lewis Practical Haematology, 10th Ed, (Churchill Livingstone: Elsevier, 2006), 271-310.
[2] R. Saxena., H. P. Pati., and M. Mahapatra, de Gruchy's clinical haematology in medical practice (Daryaganj, New Delhi: Wiley India pvt Ltd, 2013).
[3] D. Bachir, and F. Galacteros, Hemoglobin E disease.Orphanet Encyclopedia. November 2004), http://www.orpha.net/data/patho/GB/uk-HbE.pdf
[4] R. J. Laudicina, Hemoglobinopathies: Qualitative Defects. in S. B. Mckenzie and J. L. Williams, (Eds), Clinical Laboratory Haematology, 2nd Ed, (New Jersey: Pearson Education, 2010), 210-230.
[5] J. Flint., R. M. Harding., A. J. Boyce and J. B. Clegg, The population genetics of the haemoglobinopathies, Baillieres Clin Haematol, 11, 1998, 1-59...
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| Paper Type | : | Research Paper |
| Title | : | Antihypertensive Activity of Aqueous Extract of Adhatoda Vasica in Hypertensive Rats |
| Country | : | India. |
| Authors | : | Satkar Prasad || Sailesh Kumar Ghatuary || Anil Sarathe || Gaurab Duby || Kalpana Prajapati || Reena Sheride |
|
: | 10.9790/3008-1204026368 |
Abstract: The present study involved the evaluation of effectiveness of aqueous extract of Adhatoda Vasica on blood pressure, Systolic blood pressure, diastolic blood pressure and mean arterial blood pressure in the hypertensive rats. The result of present study was shown that the pretreatment with aqueous extract of adhatoda vasica (100, 200 & 400mg/Kg p.o) for six week and on the day of experiment after administration of aqueous extract of adhatoda Vasica (10, 20 & 40mg/kg i.v.) produced significant reduction in BP, SBP, DBP and MABP at different time interval in dose dependant manner...............
[1] Norman, k., shanthi, M., neal, p., Judith w. 2003. World health organization (WHO) /international society of hypertension (ISH) statement on management of hypertension, journal of hypertension, 21:1983-1992.
[2] Sharma H.L., Sharma K.K,. Principal of pharmacology, First edition, Paras medical publishing, Hyderabad, India, 2007; Page No. 227-296.
[3] Kalia A. N., Text Book of industrial pharmacognosy. New delhi India; Oscar Publication, 2005; pp 3-
[4] Kirtikar K. R. and Basu B. D., Indian Medicinal plants, text vol –III, International book distributors book sellers and publishers, Dehradun, India 2005: pp 1899-1902.
[5] Pundarikakshudu K., Kalantari H., Gotwandi G.C, Effect of Gibberlic acid on quinazoline alkaloid of Adhatoda Vasica nees. Indian drugs 23(12), 1986; Page No. 652-653....
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| Paper Type | : | Research Paper |
| Title | : | Transgenic Potato (Solanumtuberosum) Expressing Two Antifungal Thionin Genes Confer Resistance To Fusarium Spp |
| Country | : | Egypt. |
| Authors | : | I.A. Hammad || A.B. Abdel-Razik || E.R. Soliman || E. Tawfik1 |
|
: | 10.9790/3008-1204026979 |
Abstract: Two thionin genes were isolated from Arabidopsis thaliana (AT1G12660 and AT1G12663). The resulted thionin protein has antifungal activity against potato pathogenic fungi like Fusariumsolani and Fusariumoxysporum. These two thionin genes were respectively inserted into pEGAD vector. After that transformed into Agrobacterium tumifaceins GV3101::pMP90 in order to be transformed into the two potato cultivars (lady and spunta) using internodal cutting technique of tissue culture.Expressions of thionin transgenes in the transgenic plants were confirmed by..............
Keywords: Solanumtuberosum, Arabidopsis thaliana, Agrobacterium Transformation, Fusariumsolani, Fusariumoxysporum, Thionin genes
[1] J.E. Edmonds, M.S. Vorontsova, and S. Knapp, Solanaceae, In: Flora of Tropical East Africa, ed. H. Beentje, Royal Botanic Gardens, Kew, 2012.
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[3] S.I.A Elawady and A.Y. Abdulkheir, An Economic Study of the Growth Determinants for the Egyptian Potatoes Exports to the Global Market, International Journal of Economics and Finance, 7(7), 2015, 89-97.
[4] H.A.M. Mahgoub, G.S.A. Eisa and M.A.H. Youssef, Molecular, biochemical and anatomical analysis of some potato (Solanumtuberosum L.) cultivars growing in Egypt, Journal of Genetic Engineering and Biotechnology, Elseveir. 13, 2015, 39–49.
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