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Abstract: One of the plant commonly consumed in Nigeria for dietary and therapeutic purpose is Garlic (Allium sativum). Often time, the effect of the plant on the spleen is not considered by users. This present study is to investigate the histologic effect of garlic extract on the spleen of adult Wistar rats. This was a descriptive experimental study involving twenty-four (24) adult wistar rats as experimental animals. Twenty-four (24) adult Wistarrats weighing between 150-250 g were used for this research. The experimental animals were obtained from the Animal House of the faculty of Basic Medical...........
Keywords: Garlic, Wistar rats, Dietary and lymphoid tissue
[1] Eluwa, M. A., Isamoh, T. E., Asuquo, O. R., Akpantah, A. O. and Ekanem, T. B. (2013)Evaluation of Consumption of Mixed Diet of Garlic, Garden Egg and Groundnut on the Cytoarchitecture of the Spleen of AnaemicWistar Rats. International Journal of Science and Research 2(10) 2319-7064
[2] Omotoso, G. O., Saibu, S. A., Akinlolu, A. and Kadir, E. (2011) Effects of Aqueous Extract of Garlic and Vitamin C on the Kidney of Albino Rats. Asian J. Exp. Biol. Sci. 2(3) 2011: 455-461
[3] Hodge G, Hodge S, Han P. 2002. Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: potential therapeutic use in the treatment of inflammatory bowel disease. Cytometry. 48: 209–215.
[4] Kyo, E., Uda, N., Kasuga, S. and Itakura, Y. (2001). Immunomodulatory effects of aged garlic extract. supplement of conference: recent advances on the nutritional effects associated with the use of garlic. J. Nutr131: 1075–1079.
[5] Lau BHS, Yamasaki T, Gridley DS. 1991. Garlic compounds modulate macrophage and T-lymphocyte functions. MolBiother3: 103–107..
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Abstract: Since their discovery antibiotics have been central to modern healthcare and have been extensively and effectively used to prevent and treat infections in humans and animals. They have also been used in agriculture, aquaculture, and in livestock as growth promoters. In the last several years, antibiotic usage has received a lot of attention due to their emergence as a potential source of pollution. This paper collects information from other published articles on............
Keywords: Antibiotics, ecotoxicity, genotoxicity, sources, pollution, wastewater treatment plants
[1] Adams, C., Wang, Y., Loftin, K., Meyer, M. (2002). Removal of antibiotics from surface and distilled water in conventional water treatment processes. J Environ Eng, 128, 253–260.
[2] Al-Ahmad, A., Daschner, F. D., and K¨ummerer, K. (1999). Biodegradability of cefotiam, ciprofloxacin, meropenem, penicillin G, and sulfamethoxazole. Archives of Environmental Contamination and Toxicology, 37(2), 158-163.
[3] Alexy, R. (2004). What do we know about antibiotics in the environment? In: Pharmaceuticals in the Environment: Sources, Fate, Effects and Risks (Kümmerer K, ed). Berlin: Springer, 209–221.
[4] Andreozzi, R., Caprio, V., Ciniglia, C., De Champdor´e, M., Lo Giudice, R., Marotta, R., and Zuccato, E. (2004). Antibiotics in the environment: Occurrence in Italian STPs, fate, and preliminary assessment on algal toxicity of amoxicillin. Environ. Sci. Technol., 38, 6832–6838.
[5] Arriaga-Alba, M., Barrón-Moreno, F., Flores-Paz, R., García-Jiménez, E., Rivera-Sánchez, R. (1998). Genotoxic evaluation of norfloxacin and pipemidic acid with the Escherichia coli Pol A-/Pol A+ and the ames test. Archives of Medical Research, 29(3), 235-240...
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Abstract: In thepresentstudy, an easy and green method for the phytosynthesis of silver nanoparticles is reported. The leaf extract of Wedeliaurticifoliawas used for the synthesis. Overall, three ratios of leaf extract to metal salt concentrationviz 9:1, 1:1 and 1:9 were used to achieve the best ratio to be treated for getting abetter yield. The silver nanoparticles (AgNPs)synthesis was confirmed by thecolour change.The produced nanoparticles were examined by UV-Visible spectroscopy, Dynamic Light Scattering (DLS/Zeta-Sizer), XRD (X-Ray Diffraction Spectroscopy)...........
Keywords: Antibacterial activity, Biosynthesis, Silver nanoparticle, Wedeliaurticifolia,.
[1] M. Vanaja andG. Annadurai.Coleus aromaticus leaf extract mediated synthesis of silver nanoparticles and its bactericidal activity. Applied Nanoscience. 3, 2013,211–223.DOI 10.1007/s13204-012-0121-9
[2] S. Dhuper, D. Panda and P. L. Nayak. Green synthesis and characterization of zero-valent iron nanoparticles from the leaf extract of Mangiferaindica. Nano Trends: Journal of Nanotechnology. 13(2), 2012, 16–22.
[3] A. Ahmad, P. Mukherjee, S. Senapati, D. Mandal, M. I. Khan, R. Kumar and M. Sastry.Extracellular biosynthesis of silver nanoparticles using the fungus Fusariumoxysporum. Colloids and Surfaces B: Biointerfaces. 28(4), 2013, 313–318.https://doi.org/10.1016/S0927-7765(02)00174-1.
[4] T. Klaus-Joerger,R. Joerger,E. Olsson and C. Granqvist.Bacteria as workers in the living factory: metal accumulating bacteria and their potential for materialsscience. Trends in Biotechnology. 19(1), 2001, 15–20.
[5] S. Ahmed, M. Ahmad, B. L. Swami and S. Ikram. A review on plants extract mediated synthesis of silver nanoparticles for antimicrobial applications: A green expertise.Journal of Advanced Research. 7(1), 2016, 17–28.https://doi.org/10.1016/j.jare.2015.02.007...
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Paper Type | : | Research Paper |
Title | : | Changes in Nitrogen and Protein Content of Cowpea (Vigna unguiculata) due to Geminivirus Infection |
Country | : | India |
Authors | : | Shail Pande |
: | 10.9790/3008-1204052427 |
Abstract: Cowpea, Vigna unguiculata is an important legume crop cultivated worldwide as vegetable and pulse crop Cowpea is susceptible to many virus diseases amongst which geminivirus infection is more prevalent in northern India. Yellow mosaic caused by geminivirus for which whitefly acts as a vector reduces yield from 40-80% area. Virus infection generally results in the drastic bio-chemical and physiological changes in the host plants. For the estimation of protein and nitrogen, stem...........
Keywords: Cowpea, Geminivirus, Nitrogen, Protein
[1] Malathi, V.G., Usharani, J.S., Sivalingam, P.N., Rouhibaksh, A., Padma Latha, K.V. and Periasamy, M., Diversity and Complexity of Begomoviruses. Annu. Rev. Plant Pathal. 3, 2004, 225-270
[2] Singh, A.B. The Effect of Infection with Papaya Leaf Reduction Virus on the Total Nitrogen and carbohydrate Content of Papaya Leaves. Phyton (Austria) Vol. 15 Fasc. 1 — 2,1973, 37-43,
[3] Pande Shail Effect of Cowpea Golden Mosaic Virus Infection on Chlorophyll Content in Vigna Unguiculata Leaf. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 8(2), 2017, 2480-2486
[4] Plummer, D.T. An Introduction to practical Biochemistry. (Tata Mc Graw Hill, Publishing Co. Ltd.,, Bombay, 1971
[5] Bawden, F.C. and Pirie, N.W. (1952). Physiology of virus diseases. Ann. Rev. Pl. Physiol., 3 , 1952, 177 - 188.
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Abstract: Epithelial ovarian cancer contributes to a large proportion of mortality among all cancer in women due to late diagnosis at an advance stage. The present study was done on 40 ovarian cancer patients which include 35 patients wuth epithelial tumor, 3 patients with germ cell tumor, 2 patients with sex chord stromal tumorand 8 healthy controls. Objective was to test the usefulness of CHI3L1 for diagnosis of ovarian cancer at an early stage. CHI3L1 level (80.0-414.2 ng/ml) was significantly higher in ovarian cancer patients as compared control group (24.8-123.4 ng/ml..........
Keywords:Biomarker, CHI3L1, Gynaecological malignancy, Ovarian Cancer, glycoprotein
[1] A. Chetrit, G. Hirsh-Yechezkel, Y. Ben-David, F. Lubin, E. Friedman, S. Sadetzki, Effect of BRCA1/2 mutations on longterm survival of patients with invasive ovarian cancer: The National Israeli Study of Ovarian Cancer, Journal of Clinical Oncology, 26, 2008, 20-25.
[2] LAG. Ries, M. Eisner, C.L. Kosary, SEER Cancer Statistics Review.1973 – 1999. Bethesda, Md: National Cancer Institute; 2002
[3] N.S. Murthy, S. Shalini, G. Suman, S. Pruhvish, A. Mathew, Changing trends in incidence of ovarian cancer - the Indian scenario, Asian Pacific Journal of Cancer Prev, 10(6), 2009, 1025-30.
[4] I. Vind, J.S. Johansen, P.A. Price, P. Munkholm, Serum YKL-40, a potential new marker of disease activity in patients with inflammatory bowel disease, Scand J Gastroenterol, 38(6), 2003, 599-605.
[5] J.S. Johansen, B.V. Jensen, A. Roslind, D. Nielsen, P.A. Price, Serum YKL-40, a new prognostic biomarker in cancer patients, Cancer Epidemiology Biomarkers Prev, 15, 2006, 194-202..
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Abstract: Background: Malaria is one of the major public health problems in the Northeast India. Ignorance, low awareness and not prioritizing health are some of the issues in early identification and prompt treatment of diseases. Studies focusing on knowledge, attitude and practices showed that direct interaction with community plays an important role in the occurrence of malaria problem.
Aims and Objective: To assess the knowledge, attitude and awareness of malaria among the Kalita community.
Study Design: A community based descriptive cross sectional study method...........
Keywords: Malaria, Knowledge, Attitude, Dhemaji, Dibrugarh
[1]. World malaria report 2013. Geneva, World Health Organization, 2013, Available from: www.who.int/iris/bitstream/10665/97008/1/9789241564694_eng.pdf, accessed on March 11, 2014.
[2]. Ahorlu CK, Dunyo SK, Afari EA, Koram KA, Nkrumah FK., Malaria-related beliefs and behaviour in southern Ghana: implications for treatment, prevention and control. Trop Med Int Health., 1997, 2(5),488–99.
[3]. Dev V, Phookan S, Sharma VP, Anand SP., Physiographic and entomologic risk factors of malaria in Assam, India. Am J Trop Med Hyg , 2004, 71:451–456.
[4]. Singh N, Singh MP, Saxena A, Sharma VP, Kalra NL., Knowledge, attitude, beliefs and practices (KABP) study related to malaria and intervention strategies in ethnic tribals of Mandla (Madhya Pradesh). Current Science,1998.
[5]. Dharampal G. Dambhare, Shyam D. Nimgade & Jayesh Y. Dudhe, Knowledge, Attitude and Practice of Malaria Transmission and Its Preve
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Abstract: To identify the metal concentration levels of Zinc, Cadmium, Lead, Chromium, Copper, Nickel and Iron were studied in water and sediments of Kolleru Lake A.P, India. Water and sediment samples were collected monthly from the study area during October 2015 to September 2016.The samples were collected from 8 sampling stations of Kolleru Lake. Sampling stations were selected based on inlet of lake, lake points and outlet of the lake. From each sampling station water and sediment samples were collected and analyzed by using AAS. Microwave digestions have been used for sample preparation method. Metal analysis in water and sediments were calculated by.............
Keywords: Kolleru Lake, Metal analysis, Physico-chemical parameters, Sampling stations, Sediments, Water
[1]. Chandra Sekhara K ,*, Charya N.S, Kamalaa C.T, D.S. Suman Rajb C.T., Sreenivasa Rao A.c (2004)Fractionation studies and bioaccumulation of sediment-bound heavy metals in Kolleru lake by edible fish..J.Environment International 29 (2003) 1001– 1008.
[2]. Adhikari S , LopaGhosh 1,.Giri B.S 2, Ayyappan S 3 2009 . Distributions of metals in the food web of fishponds of Kolleru Lake,India J . Ecotoxicology and Environmental Safety 72 (2009) 1242–1248.
[3]. Shibani Rosyshree Mishra*, Amy L. Griffin (2010) Encroachment: A threat to resource sustainability in Chilika Lake, India J.Applied Geography 30 (2010) 448–459.
[4]. Senapathi VENKATRAMANAN1,2, Sang-yong CHUNG3, Thirunavukkarasu RAMKUMAR4, Gopalakrishnan GNANACHANDRASAMY5, Tae Hyung KIM6 (2015) Evaluation of geochemical behavior and heavy metal distribution of sediments: The case Study of the Tirumalairajan river estuary, southeast coast of India . J.International Journal of Sediment Research 30 (2015) 28-38. [5]. Andrew D.Eaton et al., 19th Edition (1995), Standard methods for the examination of water and waste water, Washington, DC, American Public Health Association, c1995.
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Abstract: The WHO defines depression as a pessimistic sense of inadequacy and a despondent lack of activity. Antidepressants are a class of drugs that reduce symptoms of depressive disorders by correcting chemical imbalances of neurotransmitters in the brain. Based on this a prospective observational study was performed in Department of Psychiatry, RMMCH, Annamalai University, TamilNadu, for a period of study 6 months; Between November 2015 and April 2016. Totally 82 patients who satisfied the inclusion and exclusion criteria were enrolled. The objectives were to observe.........
Keywords: Adverse drug reactions Antidepressants, Compliance, Medication Adherence, Patient education.
[1]. Nosé, M., Barbui, C., Gray, R., Tansella, M. Clinical interventions for treatment non-adherence in psychosis: meta-analysis. The British Journal of Psychiatry. 2003;183:197–206.
[2]. WHO. Failure to Take Prescribed Medicine for Chronic Diseases is a Massive, World-Wide Problem. 2003. Available from: http://www.who.int/mediacentre/news/releases/2003/pr54/en/
[3]. Cramer JA, Rosenheck R. Compliance with medication regimens for mental and physical disorders. Psychiatr Serv. 1998;49(2):196–201
[4]. Chakraborty K, Avasthi A, Kumar S, Grover S. Attitudes and beliefs of patients of first episode depression towards antidepressants and their adherence to treatment. Soc Psychiatry Psychiatr Epidemiol. 2009;44:482–8.
[5]. Chisholm-Burns MA, Kim Lee J, Spivey CA, et al. US pharmacists' effect as team members on patient care: systematic review and meta-analyses. Medical Care. 2010;48:923-933.
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Abstract: A study was conducted to investigate the changes insomehormones,lipid profile and liver enzymes in the first trimester pregnant Iraqi women as compared with the apparently healthy control women.A total of 60 women included30 pregnant women at first trimester selected from women admitted to Gynecology Department at Medical City of Baghdad Teaching Hospital ,all pregnant women aged between (20-35) yearsandcompared with30 apparently healthy women. The cortisol, progesterone,and prolactin hormones were measured using Biomerieux.........
Keywords: progesterone,
[1]. A.G. Guyton, Hall, Text Book of Medical Physiology. 9th ed. W.B. Saunders. Company, 2011.
[2]. A.R. Fucls, O. Behrens, and H. C. Liu, Correlation of nocturnal increase in plasma oxytocin with a decrease in plasma estradiol/progesterone ratio in late pregnancy. Am J Obstet Gynecol,167, 2000, 1559–1563.
[3]. C. Jung, J.T. Ho, D.J. Torpy, A. Rogers, M. Doogue, J.G. Lewis, J. Czajko , and J.R. Inder, A longitudinal study of plasma and urinary cortisol in pregnancy and postpartum, J ClinEndocrinolMetab., 96(5), 2011,1533–1540.
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[5]. C.A. Tiezts, W. Burtis, R. Edward, and M. Ashwood, Chemistry of pregnancy".Clinical Chemistry, 48, 2000,1740–1741
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Abstract: Transfusion-transmitted malaria unfortunately is still common in malaria endemic countries such as Nigeria because blood donors are not routinely screened for malaria before donation. Also the diagnostic method of malaria is still an issue in the scientific community. This study compared Giemsa-stained blood film microscopy and malaria rapid diagnostic test (RDT)in the determination of the prevalence of malaria parasite among blood donors in Port Harcourt, Rivers State. A total of 300 (202 male and 98 female) blood donors were studied, 123 (41.00%)were infected with malaria parasite out of which 91 (30.33%) were male and 32 (10.67%) were female.The difference in prevalence of malaria...........
Keywords: Malaria parasite; Prevalence;blood donors; microscopy; RDT; Rivers state.
[1]. Abah, A.E. and Joe-Cliff, O. (2016) Current status of malaria parasite among blood donors in Port Harcourt, Rivers State, Nigeria. Journal of Applied Science and Environmental management 20(1) 187-191.
[2]. Abba, K., Jonathan, J., Piero, L., Cho-min, N. Sally, M., Yemisi, T., Sarah, D. and Garner,P. (2012) Rapid Diagnostic tests can extend access of Diagnostic services for uncomplicated Plasmodium falciparum malaria.Cochrane Database of Systematic Reviews.
[3]. Agboola, T.F., Ajaji,M.B., Adeleke, M.A. andGyang, P.V. (2010). Prevalence of Malaria parasite among blood donors in Lagos University Teaching Hospital, Lagos , Nigeria. Annal of Biological Research, 1(3): 72-75.
[4]. Cheesbrough M., (2010). District Laboratory Practice in tropical Countries, Second edition update, 239-258.
[5]. Cheesbrough, M., (2005). District Laboratory Practice in tropical Countries, Cambridge low price editions, 239-258.
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Abstract: Cashew Nut Shell Oil (CNSO) is a versatile component of the Cashew fruit's nut shell. The CNSO is subjected to preliminary phytochemical screening with ethanol, chloroform, acetone, petroleum ether and aqueous extracts. The antibacterial activity had been tested on the CNSO extract against two Gram positive bacteria namely Staphyloccocus aureus and Enteroccocus faecalis, four Gram negative bacteria namely Escherichia coli, Klebsiella pneumonia, Pseudomonas aeruginosa and Salmonella typhi. The Antifungal activity had been tested against the growth..........
Keywords: Cashew Nut Shell Oil, Phytochemical content, Antibacterial and Antifungal activity
[1]. Subbarao N V, Krishna Prasad K M, Prasad VSRK.(2011) Review on applications, extraction, isolation and analysis of Cashew nut shell liquid.(CNSL). The Pharma Research Journal. 6(1) :21-41.
[2]. Achal (2002) Cashew :Nutrition and Medicinal value, Calarado State University.pp159-165.
[3]. Akash P, Dahale VD, Joshi, Arun BJ, (2009) Antimicrobial screening of different extract of Anacardium occidentale Linn. Leaves. Int.J.of Chem Tech Research 1: (4) 856-858.
[4]. Murthy BGK & Sivasamban MA,(1985) Recent trends in CNSL utilization. Cashew Research and Development: proceedings of the International Symposium, Cochin, Kerala, India. Pp12-15.
[5]. Rajapakse RA, Gunatillake PA, WijcoonKB, (1977) A preliminary study on processing of cashew nuts and production of Cashew Nut Shell Liquid (CNSL) on a commercial scale in Srilanka. J. of National Science Council of Srilanka. Vol.5(2) 117-124
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Abstract: Antimicrobials are probably one of the most successful forms of chemotherapy in the history of medicine. New resistance mechanisms emerge and spread globally threatening our ability to treat common infectious diseases, resulting in death and disability of individuals. In this context, this prospective observational study observes the use of antimicrobials in the department of DVL at RMMCH, Annamalai university, Tamil nadu, period of study 6 months; Between November 2015 and April 2016.The sample size comprised of 500 patients, who satisfied..........
Keywords: Antimicrobials, Antifungals, Dermatology, Resistance, Sensitivity
[1]. Goodman Gilman manual of Pharmacology and therapeutics. Edition IX
[2]. SusanY. Chon*et.al Antibiotic overuse and resistance in dermatology; Dermatologic Therapy,Vol. 25, 2012, 55–69
[3]. Lori M. Dickerson, Pharm.D* et.al, The Pharmacist's Role in Promoting Optimal Antimicrobial Use: (Pharmacotherapy 2000;20(6):711–723)
[4]. (4)World Health Organization. Bulletin of the World Health Organization vol.83: November 12, December 2005;881-968
[5]. Khan NA8 et,al Impact of Clinical Pharmacist's Intervention on Use of Antimicrobials in Dermatology Department in Tertiary Care Hospital,Indian J. Pharm. Pract. 2(2), Apr-Jun, 2009
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Abstract: Soybean is a source of vegetable protein, fats, minerals, and vitamins, currently its position as a very important raw material industry. Indonesia's soybean need reaches 2.20 million tons/year; its domestic production is sufficient 35-40%, so the shortage (60-65%) is met from import (Ministry of Agriculture 2008). The domestic need continues to increase to 9.55% per year. The entire body of S. litura is almost obscured by the white-colored mycelia. With a 109/mL density to shut down up to 50% of the population takes 5 days and 95% of death takes 10 days. B. bassiana infects the insects through the cuticle and multiplies in the body of the insect, while producing beauverisin toxins which can damage the structure of the insect cell membrane to death
Keywords: fungi; soyabean, b; conventional; hymenoptera parasitoid
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[5]. Atmadja, W. R., T. E, Wahyono, T. H. Savitri, dan E. Karmawati. 2000. Keefektifan beauveria bassiana Terhadap Helopeltis antonii SIGN. Hal:176-186 dalam P. Sukartana, I. Prasadja, M. Arifin, E. A. Wikardi, Kaomini, Soesilawati (eds) Prosiding Seminar Nasional III Pengelolaan Serangga Yang Bijaksana Menuju Optimasi Produksi, Bogor, 6 November 2001.
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Abstract: Pattern of adverse drug reaction studies in cancer patients is rare in India. Adverse drug reactions associated with the use of anticancer drugs are a worldwide problem which cannot be ignored. Adverse drug reactions can range from mild reaction like nausea, vomiting or any other to severe myelosuppression. This study was planned to observe adverse drug reactions in cancer patients receiving radiation therapy orchemotherapy aged above 18 years and visiting MGM Hospital for treatment and regular check-ups. During the study period, 201 cancer patients who came to the hospital were screened for occurrence of adverse drug reactions during their treatment with chemotherapy.........
Keywords: Adverse drug reactions [ADRs], chemotherapy. Radiation therapy, anti-cancer drugs.
[1]. Poddar S, Sultana R, Sultana R, Akbar MM, Azad MA, Hasnat A; Pattern of adverse drug reactions due to cancer chemotherapy in tertiary care teaching hospital in Bangladesh. Dhaka Univ J Pharm Sci 2009; 8:11‑6.
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[3]. Stephanie N. Schatz and Robert J. Weber; Adverse drug reactions, CNS/Pharmacy practice, PSAP 2015; https://www.accp.com/docs/bookstore/psap/2015B2.SampleChapter.pdf.
[4]. Sze Ling Chan, XiaohuiAng, Levana L. Sani, Hong Yen Ng, Michael D. Winther, Jian Jun Liu, Liam R. Brunham and Alexandre Chan; Prevalence and characteristics of adverse drug reactions at admission to hospital: a prospective observational study.Br J ClinPharmacol. 2016 Dec; 82(6): 1636–1646.
[5]. Anju Prasad, PratyayPratimDatta,Jibak Bhattacharya, ChaitaliPattanayak, Ashok Singh Chauhanand Parbaty Panda; Pattern of Adverse Drug Reactions Due to Cancer Chemotherapy in a Tertiary Care Teaching Hospital in Eastern India J Pharmacovigilance 2013, 1:2
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Paper Type | : | Research Paper |
Title | : | Bacterial Contamination of In-Use Ocular Medications |
Country | : | India |
Authors | : | Sangeetha J || Arvind prasanth D |
: | 10.9790/3008-12040596100 |
Abstract: Forty in-use ocular medications from 34 patients were collected from out-patients at Dr.Agarwal's Eye Hospital, Salem. The present study was carried out by culturing the bottle caps, the cover, nosil and a drop produced by simple inversion by standard methods. The bacterial isolates which were considered significant growth in culture media and positive for direct microscopic findings were taken for the study. These isolates were identified by standard biochemical tests. Commonly Gram positive organism were significantly (71.95%) to be isolated from all medication sites than Gram negative organism (28.04%). Gram positive organism include Staphylococcus saprophyticus..........
Keywords: Ocular medications, Eye drop bottles, Ophthalmic solutions, Bacterial contamination, Duration of use.
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