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| Paper Type | : | Research Paper |
| Title | : | Effects of Temperature, pH, and Agitation Rate on the Production of Microbial L-Arginase |
| Country | : | Nigeria |
| Authors | : | H. O. Ibrahim || A. B. Agbaje || H. A. Afolabi || H. Usman |
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: | 10.9790/3008-1305050112  |
Abstract: The enzyme arginase metabolizes L-arginine to L-ornithine and urea. Besides its fundamental role in the hepatic urea cycle, arginase is also expressed the immune system of mice and man. While significant interspecies differences exist regarding expression, subcellular localization and regulation of immune cell arginase, associated pathways of immunopathology are comparable between species. Minimal Arginine Agar (MAA) medium was prepared and used for the screening of bacterial isolates for the production of L-arginase. Colonies that formed highest pink zones were picked and maintained on the agar slants at 4°C. The zone of colour change from the agar.........
Key words: Alcaligenes, Arginine, faecalis, L-arginine, L-ornithine, urea
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[2] King, D. E., Mainous, A. G., Geesey, M. E.. Variation in l-arginine intake follow demographics and lifestyle factors that may impact cardiovascular disease risk. Nutritional Research, 28, 2008, 21–24.
[3] Wu, G., Knabe, D. A. Free and protein-bound amino acids in sow's colostrum and milk. Journal of Nutrition, 124, 1994,2437–2444.
[4] Davis, T. A., Nguyen, H. V., Garciaa-Bravo, R., et al. Amino acid composition of human milk is not unique. Journal of Nutrition, 124, 1994, 1126–1132.
[5] Wu, G., Collins, J. K., Perkins-Veazie, P., et al. Dietary supplementation with watermelon pomace juice enhances arginine availability and ameliorates the metabolic syndrome in Zucker diabetic fatty rats. Journal of Nutrition , 137, 2007d, 2680–2685.
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| Paper Type | : | Research Paper |
| Title | : | Effect of Aqueous Leaf Extract of Vernonia Amygdalina on Blood Glucose and Lipid Profile of Alloxan-Induced Diabetic Rats |
| Country | : | Nigeria |
| Authors | : | Ukpabi Chibueze || Nwankwo Juliet || Eshie Tochukwu || Isu John |
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: | 10.9790/3008-1305051317 |
Abstract: The effects of orally administered aqueous leaf extract of Vernonia amygdalina on serum glucose and lipid profile of albino rats were determined. Adult healthy rats of both sexes of about eleven weeks old were randomly assigned into six groups following acclimatization to laboratory and handling conditions. Animals in group A were not intoxicated (normal control) while group B were intoxicated and were gives access to food and water. Animals in groups C, D, E and F were intoxicated and were treated with insulin (40mg/kg), Atorvastatin(30mg/kg), low dose (200mg/kg) and high dose (400mg/kg) extracts of Vernonia amygdalina respectively. Diabetes was induced with a single dose of alloxan (100mg/kg) body weight and serum glucose was taken 72h after induction.........
Key words: Vernonia amygdalina, phytochemicals, antidiabetic and hyperlipidemic activities.
[1]. Ukpabi, Chibueze, Stephen Chinwendu, Onyeji, Maryjane and Ezeigbo, R. O. (2015). Effects of Biherbal Aqueous Extract of Vernonia amygdalina (Bitter leaf) and Gongronemalatifoluim (Utazi leaf) on alloxan induced diabetes rats. International Journal of Scientific Research and Engineering studies (2)(3): 136-140.
[2]. Murray, R. K. Granner, D. K. Mayes, P. A., and Rodwell, V. W. (2003). Harpers illustrated Biochemistry, twenty Sixth edition.
[3]. Zubay, G. C. Parson, W. W. and Vance, D. E. (1995). Principles of biochemistry WM.C. Brown Publishers, USA.
[4]. Ifeoma, I. I. and Chukwunnonso, E. C. (2011). Current perspectives on the medicinal potentials of Vernonia amygadalina Del. J. Med. Plant Res, 5: 1051-1061.
[5]. Akah, P. A. and Okafor, C. I. (1992). Hypoglycemic effect of Vernonia amygdalina in experimental rabbits Plants Med Res. 1: 6-10.
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| Paper Type | : | Research Paper |
| Title | : | Squamous cell carcinomas arising in seborrheic keratosis of external auditory canal: unusual situation |
| Country | : | Morocco |
| Authors | : | J.Benayd || I. Allouch || H.Rahim. O. Lassikri || Bencheikh R || Benbouzid MA || Oujilal A || Essakalli L. |
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: | 10.9790/3008-1305051820 |
Abstract: We report an unusual case of seborrheic keratosis (SK) of theright external auditory canal in 78-year-old female patient, revealed by right malignant otitis externa andcaused impaired hearing, by obstructing the external auditory meatus.Surgical removal of lesion was performed and histopathological examination revealed association of SK with invasive Squamous cell carcinomas.We also reviewed and discuss the aetiology, clinical and histopathological featuresand treatment strategy of these disfiguring lesions.
Key words: Seborrheic keratosis, external auditory canal, malignant otitis externa, Squamous cell carcinomas
[1]. Hafner C, Vogt T. Seborrheic keratosis. J DtschDermatolGes 2008;6:664-77
[2]. Anderson PJ, Zuk JA, Rao GS, et al. Squamous cell carcinoma arisingwithin seborrheic keratosis. PlastReconstrSurg 1998;102:453Y5.
[3]. Hafner C, Vogt T, Landthaler M, Musebeck J (2008) Somatic FGFR3 and PIK3CA mutations are present in familial seborrheic keratoses. Br J Dermatol 159(1):214–217
[4]. Kim KW1, Chang J, Lee S, Im GJ, Chae SW, Jung HH, Choi J.Clinical analysis of seborrheic keratoses in the ear: a retrospectivestudy and literature reviewEur Arch Otorhinolaryngol. 2015 May; 272(5):1113-7
[5]. IzquierdoVelásquez JC, Campos MahechaAM, Duarte Silva JP. Seborrheic keratosis of the external auditory canal. OtolNeurotol. 2012;33(7):e61-e62..
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| Paper Type | : | Research Paper |
| Title | : | Screening of indigenous plants for acetylcholinesterase inhibition by TLC bioautographic method |
| Country | : | India |
| Authors | : | E.N. Gaviraj || B. Shivakumar || S. M. Biradar || B.S. Hunasagi || V. P. Patil || S.R. Karajgi |
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: | 10.9790/3008-1305052125 |
Abstract: Acetylcholinesterase inhibition is considered as the most suitable therapeutic strategy for Alzheimer's disease. As synthetic drugs lack selective activity, efficacy and bioavailability, many traditional remedies have been explored for improving cognitive function. In the present study, indigenous plants namely Mandookaparni, Liquorice, Gaduchi, Long pepper and Ukshi were screened for acetylcholinesterase inhibition. Methanolic extracts of selected plants were prepared by soxhlet extraction and subjected to preliminary solvent-solvent extraction using dichloromethane......
Key Words: Acetylcholinesterase, active constituents, bioautography, Indian Systems of Medicine, inhibition
[1]. P.T. Francis, A.M. Palmer, M. Snape, and G.K. Wilcock, The cholinergic hypothesis of Alzheimer's disease: a review of progress, Journal of Neurology Neurosurgery Psychiatry, 66 (2), 1999, 137-147.
[2]. J.L. Cummings, Alzheimer's disease, The New England Journal of Medicine, 351 (1), 2004, 56-67.
[3]. A. Burns, and S. Iliffe, Alzheimer's disease, British Medical Journal, 338, 2009, 467-471. [4]. P.K. Mukherjee, V. Kumar, M. Mal, and P.J. Houghton, Acetylcholinesterase inhibitors from plants, Phytomedicine, 14 (4), 2007, 289–300.
[5]. S.R. Ingole, S.K. Rajput, and S.S. Sharma, Cognition enhancers: Current strategies and future perspectives, Current Research & Information on Pharmaceutical Sciences, 9 (3), 2008, 42-48..
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| Paper Type | : | Research Paper |
| Title | : | Dysphagia after anterior cervical spine surgery |
| Country | : | Iraq |
| Authors | : | Dr. Wameedh Qays AbdulHussein AlSammak || Dr. Hazim Mohammed Shni || Dr. Mohammed AbdulZehra Neat || Dr. Laith Adnan |
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: | 10.9790/3008-1305052635 |
Abstract: Cervical spondylosis is a chronic degenerative condition of the cervical spine that affects the vertebral bodies and intervertebral disks of the neck (in the form of, for example, disk herniation and spur formation), as well as the contents of the spinal canal (nerve roots and/or spinal cord). Some authors also include the degenerative changes in the facet joints, longitudinal ligaments, and ligamentum flavum. Spondylosis progresses with age and often develops at multiple interspaces. Chronic cervical degeneration is the most common cause of progressive spinal cord and nerve root compression. Spondylotic changes can result in stenosis of the spinal canal, lateral recess, and foramina. Spinal canal stenosis can lead to myelopathy1, whereas the latter 2 can cause radiculopathy.........
[1]. Ellingson BM, Salamon N, Holly LT. Advances in MR imaging for cervical spondylotic myelopathy. Eur Spine J. 2015 Apr. 24 Suppl 2:197-208.
[2]. Miranda P, Gomez P, Alday R. Acute traumatic central cord syndrome: analysis of clinical and radiological correlations. J Neurosurg Sci. 2008 Dec. 52(4):107-12; discussion 112.
[3]. Patel AA, Spiker WR, Daubs M, Brodke DS, Cannon-Albright LA. Evidence of an inherited predisposition for cervical spondylotic myelopathy. Spine (Phila Pa 1976). 2012 Jan 1. 37(1):26-9.
[4]. Young WF. Cervical spondylotic myelopathy: a common cause of spinal cord dysfunction in older persons. Am Fam Physician. 2000 Sep 1. 62(5):1064-70, 1073.
[5]. Kuijper B, Tans JT, van der Kallen BF, Nollet F, Lycklama A Nijeholt GJ, de Visser M. Root compression on MRI compared with clinical findings in patients with recent onset cervical radiculopathy. J Neurol Neurosurg Psychiatry. 2011 May. 82(5):561-3.
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| Paper Type | : | Research Paper |
| Title | : | Phytochemical Screening & Antibacterial activity of Scindapsus officinalis fruit extract against Human Pathogens: An Ethanomedicinal plant |
| Country | : | India |
| Authors | : | Manish Pathak || Amit kumar || U.K Singh |
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: | 10.9790/3008-1305053640 |
Abstract: Scindapsus officinalis used in skin diseases, asthma ulcers, leprosy, nocturnal emissions, diabetes, throat troubles, ophthalmia, tumors and dysentery. Hydro-alcoholic extract of fruits of Scindapsus officinalis were evaluated on the basis of Phytochemical, Physiochemical screening and antibacterial activity against human pathogen bacteria such as Bacillus subtilis, Bacillus cereus, Escherichia coli and Klebsiella pneumonia at various concentrations (10%, 20%, 40%, 60%, 80 %). Findings of work revealed that fruit extracts of Scindapsus officinalis have promising antibacterial properties can be of great significance in therapeutic treatments.
Key words: Scindapsus officinalis, Phytochemical Screening, Physiochemical Screening, Antibacterial activity
[1]. Artur S, Screening methods to determine antibacterial activity of Natural products, Brazilian J Microbiology 2007; 38 : 369-38. List the first two contributors followed by et al.
[2]. Selvamohan T, Antimicrobial activity of selected medicinal plants against some selected human pathogenic bacteria, Advances in Applied Science Research 2012 ; 3: 3374-3381. List the first two contributors followed by et al.
[3]. Mohamed H , Antimicrobial activity and Phytochemical analysis of selected Indian folk medicinal plants, International J Pharma Sciences and Research 2010; 1: 430-434. List the first two contributors followed by et al.
[4]. Kavit M, Antimicrobial Activity of root extract of Phyllanthus fraternus Webster: An Ethnomedicinal plant, Research J of Recent Sciences 2014; 3: 275-278. List the first two contributors followed by et al.
[5]. Velraj M, Pharmacognostical study on the fruits of scindapsus officinalis, International j of Pharmacy and Pharmaceutical Sciences 2013; 5: 1-2. List the first two contributors followed by et al..
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| Paper Type | : | Research Paper |
| Title | : | Sex hormones profiles in Iraqi males patients with symptomatic cholelithiasisbefore cholecystectomy |
| Country | : | Iraq |
| Authors | : | Shaymaa J. Mohammed || Mohammed A. Taher |
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: | 10.9790/3008-1305054147 |
Abstract: Gallstone disease (GD) is a worldwide disease and it remains to be one of the most common health problems leading to surgical intervention. GB stone formation is multifactorial &many theories have been put forwardto explainthe mechanism of stoneformation. It is not fully clear if symptomatic gallstone disease is associated with a specific pattern of some hormonal abnormalities in the serum of male with symptomatic gallstone. The objective is to find the relationship between serum levels of sex hormones (free testosterone, SHBG, dihydrotestosterone (DHT),estradiol (E2), and progesterone)and gallstone formation in men.This cross-sectional study was carried on 50 males' patients and 37 healthy males as control group. After 12 hrs fasting, blood samples were collected from all subjects to evaluate the serum levels of thesex hormones (free testosterone, SHBG, dihydrotestosterone........
Key words: Gallstone disease, sex hormones, males'patients.
[1]. Pradhan SB1, Joshi MR2, Vaidya A: Prevalence of different types of gallstone in the patients with cholelithiasis at Kathmandu Medical College, Nepal. Kathmandu University Medical Journal 2009; 7(3): 268-271.
[2]. Russo MW, Wei JT, Thiny MT, et al: Digestive and liver diseases statistics, 2004. Gastroenterology 2004; 126: 1448-1453.
[3]. Sandler RS, Everhart JE, Donowitz M, et al: The burden of selected digestive diseases in the United States. Gastroenterology 2002; 122:1500-1511.
[4]. PieroPortincasa, Antonio Moschetta, Giuseppe Palasciano: Cholesterol gallstone disease. Lancet 2006; 368: 230–239.
[5]. Leonard V. Crowley: An introduction to Human Disease. 9th ed. Jones & Bartlett Publishers, Canada, 2010 pp: 539-563.
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| Paper Type | : | Research Paper |
| Title | : | Algorithms for Search for Common Ancestors |
| Country | : | India |
| Authors | : | Rita Gitik |
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: | 10.9790/3008-1305054853 |
Abstract: Generation theory was developed as a tool for studying self-reproducing systems. In this paper we show that this theory can be applied to a search for common ancestors of living organisms. We give two algorithms with flowcharts in pseudocode for finding common ancestors of a set of microbes and describe the connections with the genography problem.
Key words: Algorithm, Flowchart, Microbe, DNA, Graph
[1]. Doron M. Behar et al, The Genographic Project Public Participation Mitochondrial DNA Database, PLoS Genetics, 2007, 3, 1083-1095.
[2]. R. Gitik, Generation Theory: Application to Self-Reproducing Systems and Mathematical Insights, University of Michigan Control Group Report, CGR-06-14, 2006.
[3]. R. Gitik, Optimal Seeding and Self-Reproduction from a Mathematical Point of View, J. of Computer Engineering, IOSR, September – October 2016, 18, Issue 5, Version 5, pp. 56-59.
[4]. A. J. F. Griffiths et al, An Introduction to Genetic Analysis, W. H. Freeman, 1999.
[5]. Y. Haile-Selassie et al, New Species from Ethiopia Further Expands Middle Pliocene Hominin Diversity, Nature, 28 May 2015, 521, 483-488..
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| Paper Type | : | Research Paper |
| Title | : | Preliminary Phytochemical , Chromatographic And Antimicrobial Evaluation Of Ethanol Leaves Extract And Fractions Of Andrographis Paniculata (Burm.F.) Nees Family Acanthaceae |
| Country | : | Nigeria |
| Authors | : | T. U Onyekaba || Nwoye David Ifeanyi || Anowi Chinedu Fredrick |
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: | 10.9790/3008-1305055464 |
Abstract: This study is designed to examine the ethanol leaves extract of Andrographis paniculata (Burm.f.) Nees family acanthaceae for its in vitro antimicrobial potential against strains of Streptococcus pneumoniae, Escherisha coli, Pseudomonas aeruginosa and Candida albicans at five concentrations; 200, 100, 50, 25 and 12.5mg/ml respectively by agar well diffusion method to ascertain its folkloric claim to treat various infectious diseases. The extracts showed significant broad spectrum antibacterial activity. The minimum inhibitory concentration of the bacteria ranged between 7mg/mL and 12.5mg/mL while that of Candida albicans was 1.42mg/mL. Phytochemical analysis revealed the presence of terpenoids, tannins, flavonoids, saponins, alkaloids, reducing sugar, steroids........
[1]. Abubacker1 M. N., and S. Vasantha (2010); Antibacterial Activity of Ethanolic Leaf Extract of Andrographis paniculata Nees (Acanthaceae) and Its Bioactive Compound Andrographolide, Drug Invention Today, 2(10),440-442.
[2]. Akindele AJ and Adeyemi OO(2007). Anti‐inflammatory activity of theaqueous leaf extracts of Byrsocarpus coccineus. Fitoterapia.
78: 25‐28.
[3]. Chinedu Fredrick Anowi, Nnabuife Chinedu Cardinal, C.J. Mbah and T.C.Onyekaba; Antimicrobial Properties of the Methanolic Extract of the Leaves of NauclealLatifolia (2012) Int. J. Drug Res. Tech., . 2 (1), 45-55.
[4]. Coon JT and Ernst E. (2004); Andrographis paniculata in the treatment of upper respiratory tract infections: a systematic review of safety and efficacy. Planta Med pp 293–298.
[5]. European Committee on Antimicrobial Susceptibility Testing (EUCAST);(2000). Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by agar dilution. EUCAST Definitive Document E.Def 3.1. Clinical Microbiology & Infection Journal 6: 509-15..
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| Paper Type | : | Research Paper |
| Title | : | Cytotoxic Effect of Methotrexate on Leishmaniadonovani Promastigotes |
| Country | : | Iraq |
| Authors | : | Buraq Abdualameer Fingan || Hayder Zuhair Ali |
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: | 10.9790/3008-1305056569 |
Abstract: Leishmania is auxotroph to folic acid,antifolates drug inhibit the synthesis and conversion of folate derivatives. In this study, cytotoxic effect of methotrexate was investigated on the procyclic promastigotes proliferation of L. donovani.The results showed a significant (p ≥ 0.05) difference in growth of treated groupsat high concentrations (1000, 500, 250, 125.5) μM after 24, 48 hrs., while at 72 hrs. significant difference was observed at all concentration. The IC50 values was measurable after 24, 48 and 72 hrs. and it was 174.238, 52.283 and 109.175 μM, respectively. The present study showed the cytotoxic effect of methotrexate on the proliferation of promastigotes of the visceral type of Leishmania.
[1]. Salam N, Al-Shaqha WM, Azzi A. Leishmaniasis in the Middle East: incidence and epidemiology. PLoS neglected tropical diseases. 2014;8(10):e3208.
[2]. Kevric I, Cappel MA, Keeling JH. New world and old world Leishmania infections: a practical review. Dermatologic clinics. 2015;33(3):579-93.
[3]. McGwire B, Satoskar A. Leishmaniasis: clinical syndromes and treatment. QJM: An International Journal of Medicine. 2013;107(1):7-14.
[4]. Díaz E, Köhidai L, Ríos A, Vanegas O, Silva A, Szabó R, et al. Leishmania braziliensis: Cytotoxic, cytostatic and chemotactic effects of poly-lysine–methotrexate-conjugates. Experimental parasitology. 2013;135(1):134-41.
[5]. Stoops CA, Heintshcel B, El-Hossary S, Kaldas RM, Obenauer PJ, Farooq M, et al. Sand fly surveillance and control on Camp Ramadi, Iraq, as part of a leishmaniasis control program. Journal of Vector Ecology. 2013;38(2):411-4...
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| Paper Type | : | Research Paper |
| Title | : | Qualitative Assessment of Parent's Roles and Views Towards Secondary School Adolescentsexual Behaviour In Cross River State |
| Country | : | Nigeria |
| Authors | : | Lilian Eberechukwu Eyam || Eyam Sunday Eyam || Kaka Agbo Ochago || Theresa Bassey Cletus |
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: | 10.9790/3008-1305057076 |
Abstract: Parents play an important role in the activities of their children because they are frequently in contact with these adolescents and they help to shape their behaviour and the social context in which they grow up. They are therefore expected to watch-over their children's sexual activities as well as identify, sieve and package information and services for them. A study to determine the role of parents in adolescents' sexual behaviour in co-educational secondary schools in Cross River State was done. The specific objectives were to determine parents'/adolescents' relationship, the degree to which parents monitor and supervise their adolescents, assess the level at which parents communicate with their adolescents and how much material support parents give to their adolescents. Parents of adolescents in secondary school were used. Two schools were randomly selected and twenty.......
[1]. Aspy CB, Vesley SK, Oman RF, Rodine S, Mcleroy K, (2007). Parental communication and youth sexual behaviour. Journal of adolescence. 30(449-466) Pubmed
[2]. Borawski E, Levers-Landis C, Lovegree L, and Trapl E (2003) Parental monitoring, negotiation unsupervised time and parent trust. The role of perceived parenting practices in adolescent health risk behaviour. Journal of adolescents Health 33(2), 60-70
[3]. Cence, M. (1997). Rode kaart of carte blanche. Risicofactoren voor seksuele intimidatie en seksueel misbruik in de sport [Red card or carte blanche. Risk factors for sexual intimidation and sexual abuse in sport]. Utrecht, the Netherlands: Taluut. Surveilliance . Report 18: 1-34
[4]. Chimaraoke, Otutubike and yIzugbara.( 2001) Tasting the forbidden fruit: The social context of debut sexual encounters among young persons in a rural Nigerian community. African Journal of Reproductive Health; 5(2): 22-29.
[5]. Fatusi AO, Blum RW (2008): Predictors of early sexual initiation among a nationally representative sample of Nigerian adolescents. Biomedical Central Public Health, 8:136...
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| Paper Type | : | Research Paper |
| Title | : | A Comparative Study on Academic and Nursing Students with a View to Develop a Guideline for Management of Swine Flu In Reference To the Knowledge Regarding Swine Flu |
| Country | : | India |
| Authors | : | ROJARANI.K |
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: | 10.9790/3008-1305057785 |
Abstract: Background of the study: This study talk about the swine flu centers around various view points, for example, the study of disease transmission, medications, and preventive proportions of swine influenza. This is caused due to H1N1 spoiling and this contains eight strands, one of them is gotten from the strains of human influenza and 2 are from the strains of avian and the other 5strands are gotten from swine strains.The aim of the study was to develop a guideline for management of swine flu in reference to the knowledge regarding swine flu Methodology: The study was conducted an Akhil Bharati Vidyapeeth College of Nursing, KGN College of Nursing Colleges, and for the b.sc. Student colleges.......
Keyword:knowledge, regarding, prevention, colleges, develop, guideline, management Swine flu.
[1]. Pandemic InfluenzaA (H1N1), donor report, March1, 2011.Weekly update of the pandemic (H1N1) 2009. August 5, 2010. World Health Association, 2009:2.
[2]. Chaudhary V RK Singh, VK Agrawal, Agarwal A, Kumar R, Sharma Lord mindfulness, perception and myths about the swine flu flu among schoolchildren in Bareilly, Uttar Pradesh. Indian J Public Health. 2010; 54 (3): 161-61.4th
[3]. Singh S, P Kaur, Singh focused G. In assessing consciousness, perception and myths in what refers to the swine flu Common Public Trained in Patiala district.IntJRes Dev Health. 2013; 1 (2): 54-4.60
[4]. Rathi S, M Gandhi, Francis M. Knowledge and awareness of the flu H1N1 in the population adult urban Vadodara, India, studied electronic physics year. 2011; 3: 392-; 5
[5]. Seale H, Mak JP, Razee H, MacIntyre CR. Analyze the knowledge, mentalities and practices of local and global university studies on occasional and pandemic influenza. BMC Public Health. 2012; 12:307..