Abstract: Botanical profile: Guizotia abyssinica (L. f.) cass. of family Asteraceae (Compositae) is an oilseed crop cultivated in Ethiopia and India. It is a moderately to well branched herb which grows up to 2 m tall. The seed contains about 40% oil with fatty acid composition of 75-80% linoleic acid, 7-8% palmitic and stearic acids, and 5-8% oleic acid. In the present investigation phytochemical profile of Niger seeds was assayed qualitatively and quantitatively in six solvent extracts viz. acetone, petroleum ether, ethanol, methanol, benzene and distilled water. The results revealed the presence of various phytochemicals such as tannins, phlobatannins, saponins, terpinoids, diterpinoids, emodins, flavonoids, cardiac glycosides, anthraquinones, carotenoids, reducing sugars, alkaloids, anthocyanin, coumarins, steroids, phytosterols, phenol, fatty acids, proteins and amino acids. terpenoid, diterpinoid, emodin, cardiac glycoside,
Keywords: Guozotia abyssinica, Niger, Ramtil, Phytochemicals, acetone, petroleum ether, ethanol, methanol, benzene and distilled water.