iosr-JDMS   Volume-18 ~ Issue-11 ~ November-2019

Abstract: Alcohol abuse is emerging as a global burden and causes a substantial health loss. Alcohol while using causes no significant effects but its abrupt withdrawal causes deleterious effects. In this study baclofen is used as a novel drug to overcome the alcohol withdrawal effects. Aim: The main objective of the study was to determine baclofen as a safe and effective treatment option for alcohol withdrawal syndrome. Materials and methods: A total of sixty nine patients were enrolled in the study by using CIWA-Ar (clinical institute withdrawal assessment) scale in ACSR GOVT medical college from September 2018 to February 2019. Patients who were attended for three follow ups their CIWA-Ar score is measured and noted. CIWA-Ar scale was used only to evaluate physical symptoms.....

Keywords: Alcohol withdrawal syndrome, baclofen, GABAB analogue

[1]. A Randomized, Open-Label, Standard Controlled, Parallel Group Study of Efficacy and Safety of Baclofen and Chlordiazepoxide In Uncomplicated Alcohol Withdrawal Syndrome By,K.Girish10.1016
[2]. .Baclofen In the Treatment of Alcohol Withdrawal Syndrome: A Comparative Study Vs Diazepam Giovanni addolorato 10.1016/J.Amjmed.2005.08.042
[3]. Baclofen in Managing Acute Alcohol Withdrawal: Preliminary Findings from a Randomised Controlled TrialS.Jegham 10.1016/j.euroneuro.2017.12.102
[4]. Baclofen for the Treatment of Alcohol Use Disorder: The Cagliari StatementRobertaagabio 10.1016/s2215-0366 (18)30303-1
[5]. Baclofen as Add-On to Standard Psychosocial Treatment for Alcohol Dependence: A Randomized, Double-Blind, Placebo-Controlled Trial with 1 Year Follow-UpAlexander M.Ponizovskym.D, Ph.D. 10.1016/J.Jsat.2014.11.007.

Abstract: Venous thrombosis of lower limb is a prevalent condition. Many different imaging modalities were used for its diagnosis. Phlebography is considered the gold standard modality for its diagnosis. Recently, color Doppler has evolved as an easily available, repeatable, non-invasive, dynamic modality. In our study 40 patients who were clinically suspected to have thrombosis were further examined on color Doppler.Majority of the patients were male (72.5%) in the age group of 41 – 50 years (30%). Most of the patient had unilateral (94.12%) involvement in which left lower limb was predominantly involved (70.59%). Superficial femoral vein (79.41%) was more commonly involved followed by common femoral vein (67.65%) and popliteal.........

[1]. Agarwala S, Bhagwat AS, Modhe J. Deep vein thrombosis in Indian patients undergoing major lower limb surgery. Indian J Surg 2003;65:159-62.
[2]. Chinglensana L, Rudrappa S, Anupama K, Gojendra T, Singh KK, Chandra ST. Clinical profile and management of deep vein thrombosis of lower limb. J Med Soc. 2013;27:10-4.
[3]. Huisman MV, Klok FA. Diagnostic management of acute deep vein thrombosis and pulmonary embolism. J Thromb Haemost. 2013;11:412-22.
[4]. Galson SK. Prevention of deep vein thrombosis and pulmonary embolism. Public Health Rep 2008;123:420-1
[5]. Tovey C, Wyatt S. Diagnosis, investigation, and management of deep vein thrombosis. BMJ 2003;326:1180-4..

Abstract: Vaginal bleeding in the first trimester is a common obstetric situation ranging from an insignificant episode to a life threatening emergency. The major causes are abortion, ectopic, and molar pregnancy. It occurs in about a one fourth of pregnancies, approximately half of whom will miscarry [5], while the other half will stop bleeding and complete a normal pregnancy. Ultrasonography is playing an increasing role in the diagnostic process. This study was taken up to evaluate its utility vis-à-vis clinical examination findings. Our study has been done on 50 patients with per-vaginal bleeding in the first trimester of pregnancy who were referred to the department of Radio-diagnosis were studied on TVS after taking consent. In the present study, the most common cause of bleeding in first trimester was missed abortion. The next common cause was Threatened abortion........

[1]. Rumack CM, Wilson SR, Charboneau JW, Levine D, editors: Diagnostic Ultrasound, 4th Edition, Volume 2. U.S.A, Mosby (an affiliate of Elsevier); 2011;1041-1088.
[2]. Bhoj M et al. Int J Reprod Contracept Obstet Gynecol. 2019;8(4):1568-1574.
[3]. Creinin, schwartz J, Guido R, et al. early pregnancy failure–current management concepts. obstet gynecol surv. 2001;56(2):105–113.
[4]. Chen ba, Creinin, contemporary management of early pregnancy failure. clin obstetgynecol. 2007;50(1):67–88.
[5]. Paspulati RM, Bhatt S, Nour S. sonographic evaluation of first-trimester bleeding. radiolclin north am. 2008;46(2):437

Abstract: Magnetic resonance imaging (MRI) is playing an increasingly important role as an non-invasive test for determining the patients of shoulder pain. Aims and Objectives:To assess the role of MRI in the diagnosis and detection of shoulder pain. Results:Among the 100 patients included in the study joint effusion (64%) is the most common pathology, followed by rotator cuff tears (50%), tendinopathy (46%), degenerative diseases(42%) and bursitis(34%). Hill Sachs lesion was observed in 20% patients while Bankarts lesion / Variants in 24% patients. Malignant tumor was present in 1 patient. Conclusion: We recommend the state-of-the-art conventional MRI, be performed in shoulder pathologies in patients with aching shoulder as it is non-invasive, non-ionizing radiation, high degree of resolution and good soft tissue contrast.

Keywords: MRI, Shoulder

[1]. Papatheodorou A, Ellinas P, Takis F, Tsanis A, Maris I, Batakis N. US of The Shoulder- Rotator cuff and Non rotator cuff Disorders. Radiographics. 2006;26:23.
[2]. Farber JM, Buckwalter KA. Sports-related injuries of the shoulder: instability. Radiologic clinics of North America. 2002;40(5):235-249.
[3]. Brox JI. Regional musculoskeletal conditions: shoulder pain. Best Pract Res ClinRheumatol. 2003;17(1):33-56.
[4]. Murphy RJ, Carr AJ. Shoulder pain. BMJ ClinEvid. 2010;1107.
[5]. Ludewig PM, Cook TM. Alterations in shoulder kinematics and associated muscle activity in people with symptoms of shoulder impingement. PhysTher. 2000;80(3):276-91.

Abstract: Papillomaviruses are ubiquitous and are members of a family Papillomaviridae of DNA viruses that infect humans and animals. Human papillomaviruses (HPVs) are small non-enveloped viruses that contain a double-stranded, closed circular DNA genome. Human papillomaviruses cause anogenital warts and are associated with anogenital malignancy including cervical, vaginal, vulvar, penile, and anal carcinoma.This study was carried out to determine the prevalence of HPV IgM among women of reproductive age and associated risk and demographic factors in Funtua zone, Katsina state. A cross-sectional serological survey enrolling 60 women of reproductive age attending ANC of General Hospital Funtua. Serum samples were obtained from randomly selected subjects.....

Keywords: HPV, DNA, prevalence, IgM, ELISA.

[1]. American Cancer Society (2014). Cancer facts and Figures 2014 exit Disclaimer. Atlanta: American Cancer Society.
[2]. Auwal I.K, Amin M, Atanda, Tukur J, and Sarkinfada F, (2013). Prevalence and risk factors of high risk Human Papilomavirus infection among women attending gynecology clinics in kano, Northen Nigeria. Bayero journal of pure and applied sciences, 6(1): 67-71.
[3]. Bashir A, Abdulmalik YB, Musa SK, Mukhtar GL, Muhammad HR, Ummusalma AS, Bahauddeen SD, Sani A and Saddig AB, (2017). Academic project write-up and data analysis: A workshop manual prepared and organized by department of microbiology faculty of natural and applied sciences umaru musa yar'adua university, katsina, (14-16).
[4]. Bruni, L., Barrionuevo-Rosas, L., Albero, G., Serrano, B., Mena, M., Gomez, Z., Muñoz, J., Bosch, FX., de, SS. Human Papillomavirus and related diseases report. ICO Information Centre on HPV and Cancer (HPV Information Centre); 2016.
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Abstract: Introduction: Due to increasing incidence of cirrhosis we can use biomarker like serum prolactin which is elevated in cirrhosis patients. It also predicts the severity and complications of cirrhosis, so it may be helpful for early intervention[1]. Aims and Objectives: The study is done to find the correlation between Child Pugh scoring which is used to determine the severity of cirrhosis and serum marker Prolactin. Materials and Methods:The study was conducted among 100 cirrhosis patients in Govt. Stanley Medical College and hospital Statistical Analysis: The data was analyzed using SPSS version 16 and Microsoft Excel 2007. Summary:.

Keywords: Cirrhosis, Child Pugh score, Prolactin,

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[4]. Prolactin levels in cirrhosis patients correlates with severity of liver disease , Juraj payer, Tomas koller , Lahim baqi and Jana kollarova, Endocrine abstracts 2008.
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Abstract: Primary bone lymphoma is a rare entity in itself. A number of studies on primary bone lymphomas have been reported from western countries but only a few reports are available from Asia....

[1]. https://www.archivesofpathology.org/doi/pdf/10.1043/1543-2165-133.11.1868
[2]. 2.Primary bone lymphoma: A case report and review of the literature HAI-YAN ZHOU, FANG GAO, BING BU, ZHENG FU,XU-JIE SUN,CHENG-SUO HUANG, DENG-GUANG ZHOU, SHU ZHANG, and JUN XIAO
[3]. A Highly Curable Lymphoma Occurs Preferentially in the Proximal Tibia of Young Patients M. Kristina Subik,#, Megan Herr,# Robert E. Hutchison,Jennifer Kelly,Wakenda Tyler, Mihai Merzianu, and W. Richard Burack
[4]. Lakshmaiah, et al.Primary non-Hodgkin's lymphoma of bone: poly-ostotic versus mono-ostotic subtypes ecancer
[5]. A highly curable lymphoma occurs preferentially in the proximal tibia of young patients. Subik MK#, Herr M#, Hutchison RE, Kelly J, Tyler W, Merzianu M, Burack WR..

Abstract: High altitude and associated high altitude illnesses have always been an issue of concern especially in western Himalayan region and northern India. Ladakh has been stated to cause maximum number of cases of high altitude illness. This study was taken to assess the incidence of High altitude illness (HAI) among low landers adult males on rapid exposure to high altitude region and the association of altitude range and acclimatization schedule. An observational study was done prospectively in Ladakh region and all the reported cases of high altitude illness were assessed for two consecutive years. The overall incidence of high altitude illness were 7.6/1000 and 9.2/1000 in.....

Keywords: High altitude illness, acute mountain sickness, acclimatization schedule, high altitude pulmonary edema, high altutitude cerebral edema,

[1]. Terra Daily (News about planet earth), Altitude sickness worst in northern India by staff writers, New Delhi (UPI)Oct 31, 2011.to
[2]. Jean Paul Richalet .Physiological Risk Factors For Severe High Altitude Illness, A Prospective Cohort Study; American Journal Of Respiratory And Critical Care Medicine. Vol 185, No 2, Jan 2012.
[3]. Dash UK, Karamkar AA, Dangi MS. A Study of High-Altitude Associated Conditions in Soldiers less than 50 years of age admitted in the ICU of a tertiary care military hospital operating in a counter insurgency operation area. J Mar Med Soc 2017; 19: 138-41.
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Abstract: Now-a-days; facial appearance and smile are becoming very necessary for everybody psychologically as well as aesthetically. Traumatic dental injuries cause functional disturbances. Most commonly maxillary centrals are involved followed by maxillary laterals and mandibular incisors because of fall in children and contact sports in adoloscents. Here, a case of complicated crown fracture of tooth number 11 and 21 in a 14 year old boy is presented. Ellis class VIII fracture tooth was restored with conservative approach of root canal treatment followed by prosthetic treatment by post and core and Porcelain Fused to Metal crown.The patient was asymptomatic clinically and radiographically after 3 months follow up. It is not always necessary to go for extraction in Ellis Class VIII fracture....

Keywords: Dental trauma, Ellis class VIII fracture, Post and core, Single visit Endodontics

[1]. Kang Y, Franco CS. A story of dental injury and orthodontics. Oral Health Dent Manag 2014;13:243-53.
[2]. Kaushik S, Sharma R, Sharma V, Setya G, Assudani G, Arora A. Management of anterior tooth trauma: Two case re-ports.Endodontology 2016;28:64‐7.
[3]. Geeta, Preethi S.Managment of complex crown root fracture using fibre post – A case report. Endodontology 2014;26:211-6.
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[5]. Patel R, Miner JR, Miner SL. The need for dental care among adults presenting to an urban ED. Am J Emerg Med 2012; 30:18‐25..

Abstract: Aim: To study the role of intravitreal Anti-VEGF as an adjunct in medical & surgical management of neovascular glaucoma. Methods: this hospital based interventional study was conducted on 50 patients, with the clinical presentation suggestive of neovascular glaucoma, after an extensive clinical evaluation. Intravitreal Anti-VEGF was given and the effect was recorded on subsequent follow up. Panretinal photocoagulation was done as soon as media clarity permitted. In refractory cases, trabeculectomy with mitomycin C was done Results: The common mechanism of neovascular glaucoma was CRVO (60%) and PDR (40%).Mean age was 58.44 years. There was a significant improvement in visual acuity (p= 0.0015) and intraocular pressure (IOP) (p=0.0000) at the end of 16 week.....

Keywords: neovascular glaucoma, Anti-VEGF, trabeculectomy with mitomycin C

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Abstract: Background: Acute abdominal pain is a common chief complaint in patients examined in the emergency department (ED) and can be related to a myriad of diagnoses. Of all patients who present to the ED, 10% have acute abdominal pain. Obtaining a careful medical history and performing a physical examination are the initial diagnostic steps for these patients. On the basis of the results of this clinical evaluation and laboratory investigations, the clinician will consider imaging examinations to help establish the correct diagnosis. Aim of Study: To determine the accuracy of the Ultrasonography and the computed tomography in evaluation of patients presenting with acute abdominal pain and to decide which is superior to other regarding sensitivity and specificity......

Keywords: Ultrasound , Computerized Tomography, Acute Abdominal Pain

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Abstract: Aim: To determine the association between dyslipidemia and MGD. Settings and Design: it is a prospective, observational study of 1 year duration. Thirty patients who were diagnosed with meibomian gland dysfunction and 30 age and sex matched controls were taken into study after they gave their informed consent and taking into consideration the inclusion and exclusion criteria. Methods and Material: Meibomian gland status was evaluated by, expressibility, and numerical scoring of staining. test was done by taking venous sample of blood in a red-topped vacutainer after overnight fasting. Values of total cholesterol (TC), high-density lipoprotein (HDL) , low-density lipoprotein (LDL), and triglycerides (TGs) were noted....

[1]. Nelson JD, Shimazaki J, Benitez-del-Castillo JM, Craig JP, McCulley JP, Den S, et al. The International Workshop on Meibomian Gland Dysfunction: Report of the Definition and Classification Subcommittee. Invest Ophthalmol Vis Sci [Internet]. 2011 Mar 1 [cited 2019 Aug 16];52(4):1930–7. Available from: https://iovs.arvojournals.org/article.aspx?articleid=2126284
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[4]. Nichols KK, Foulks GN, Bron AJ, Glasgow BJ, Dogru M, Tsubota K, et al. The International Workshop on Meibomian Gland Dysfunction: Executive Summary. Invest Ophthalmol Vis Sci [Internet]. 2011 Mar 1 [cited 2019 Oct 15];52(4):1922–9. Available from: https://iovs.arvojournals.org/article.aspx?articleid=2126267
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Abstract: Cerebral palsy is a static, non-progressive disorder caused by brain insult or injury in the prenatal, perinatal and postnatal time period, it is one of the major developmental disability which ranges from mild to total handicap, as care giving is associated with high rates of awareness on various services to manage of children, they need support of family and community members such as neighbours, parents experience states of depression, physical and psychological difficulties in supporting the child, Siddha system of medicine reduces the burden of parents for which the arrive to Siddha, investigation conducted among 100 parents of cerebral palsy children with age group between 2 to 12 years in both male and female children, results of this study suggest that the number of non-consanguineous parents is 59%,in gender distribution female children is more which is 51%, the birth asphyxia contributing to 48% of cerebral palsy children, awareness about their children illness and other availability......

[1]. Palpandian, Siddhas masters of the basics,achala siddha, 2008.p.no.85, 103
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[3]. O.P.Ghai,Piyush gupta,V.K.Paul,Ghai Essential Paediatrics,CBS Publishers and distributors, New Delhi and Bangalore ,6th edition, 2004,,p.no.540
[4]. Raju sharma, AGK Sinha, A Study on awareness, beliefs, and service utilization among families of children with cerebral palsy in Jalandhar District of Punjab,2014, volume 1 , Issue 3, pg. no.170-175.
[5]. Mahendra rana,Jyotiupadhyay,Asystematic review on etiology,epidemiology and treatment of cerebral palsy, international journal of nutrition,pharmacology,neurological diseases,2017,volume 7,issue p.n.76

Abstract: Aims & objectives: To evaluate the outcome of concomitant use of conjunctival tissue graft from pterygium itself without use of glue or sutures in primary pterygium surgery. Materials & Methods: Study was conducted on 25 patients whose age>30 yrs with thorough ocular examination and blood investigationsrequired for surgery. After peribulbar anesthesia, thin layer of conjunctival graft was fashioned from pterygium tissue .This conjunctival layer from the pterygium itself was then separated completely from the underlying fibrovascular tissue and kept onto the corneal surface.....

Keywords: Conjunctiva, pterygium ,autograft , fibrin glue , glaucoma , pterygium recurrence.

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