iosr-JDMS   Volume-18 ~ Issue-3 ~ March-2019

Abstract: IgG4-related disease (IgG4-RD) is a newly recognized disorder, characterized by massive IgG4+ lymphocyte and plasma cell infiltration, storiform fibrosis, causing enlargement, nodules or thickening of the various organs, simultaneously or metachronously [1–4]..The present case report describes the clinical case of a 62 year male with complaint of fever, jaundice, abdominal pain & loss of weight since 1 month. CECT Whole Abdomen shows hepatospleenomegaly,subdiaphragmatic and abdominal lymphadenopathy .Exploratory laparotomy done & abdominal lymph nodes sent for histopathology shows features of Florid follicular lymphoid hyperplasia with infilteration by plasma cells........

[1]. Masaki Y, Shimizu H, Sato Nakamura T, Nakamura T, Nakajima A, Iwao KH. IgG4-related disease: diagnostic methods and therapeutic strategies in Japan. J Clin Exp Hematop. 2014;54(2):95–101.
[2]. Stone JH, Zen Y, Deshpande V. IgG4-related disease. N Engl J Med.2012; 366:539–51.
[3]. Woo CG, Yook JH, Kim AY, Kim J. IgG4-related disease presented as a mural mass in the stomach. J Pathol Transl Med. 2016;50:67–70.
[4]. Koizumi S, Kamisawa T, Kuruma S, Tabata T, Chiba K, Iwasaki S. Immunoglobulin G4-related gastrointestinal diseases, are they immunoglobulin G4-related diseases. WJG. 2013;19(35):5769–74
[5]. Decker L, Crawford AM. Orenzo GL, et al. IgG4-related Hypophysitis: case report and literature review. Cureus. 2016;8:e907.

Abstract: Background: Studies from different developed countries & south-east Asian countries revealed sudden increase in syphilis cases in the last decade especially in MSMs. Reports in India showed increase in latent syphilis cases. Aims and objectives: 1.To Know the prevalence of syphilis and its sub-types 2.To know its relationship to sexual practices and occurrence of syphilis Methodology: All patients attending DVL OP with H/O sexual contact interviewed and examined. Those cases with syphilis, their age............

Key Words: Syphilis Upsurge Latent syphilis MSMHIV Pregnancy

[1]. International journal of research in Medical sciences
[2]. Asian pacific journal of tropical biomedicine
[3]. Indian journal of medical microbiology
[4]. Morton RS. The treponemas. In: Rook A, Wilkinson DS, Ebling FJ, Champion RH, editors. Textbook of Dermatology. 4th ed. London: Blackwell; 1986. pp. 839–83.
[5]. Thin RN. Early syphilis in the adult. In: Holmes KK, Mardh PA, Sparling PF, Wiesner PJ, editors. Sexually Transmitted Diseases. 2nd ed. New York: McGraw-Hill; 1990. pp. 221–30.

Abstract: Introduction: Canal perforation is an undesired complication that can occur during endodontic procedures. Earlier inadequacy of repair materials had contributed to the poor outcome of repair procedures. This case report includes cases of perforation repair with Mineral Trioxide Aggregate (MTA), which has recently shown successful outcome. Method: The perforations were cleaned with sodium hypochlorite and saline and sealed with MTA without internal matrix. Result: After 1 year, the absence of periradicular lesions, pain, and swelling along with functional tooth stability indicated the successful use of MTA for repair. Conclusion: MTA has shown great potential as a material for repair of perforations.

Key Words: furcation, management, mishaps, transportation

[1]. Fuss Z, Trope M. Root perforations: classification and treatment choices based on prognostic factors. Endod Dent Traumatol. 1996 Dec;12(6):255–64.

[2]. Beavers RA, Bergenholtz G, Cox CF. Periodontal wound healing following intentional root perforations in permaent teeth of Macaca mulatta. International Endodontic Journal. 1986 Jan;19(1):36-44.

[3]. Hartwell GR, England MC. Healing of furcation perforations in primate teeth after repair with decalcified freeze-dried bone: a longitudinal study. Journal of endodontics. 1993 Aug 1;19(7):357-61.

[4]. Perdigão J, editor. Restoration of Root Canal-Treated Teeth: An Adhesive Dentistry Perspective. Springer; 2015 Oct 2.

[5]. Koh ET, McDonald F, Ford TR, Torabinejad M. Cellular response to mineral trioxide aggregate. Journal of Endodontics. 1998 Aug 1;24(8):543-7.

Abstract: Seizure are one of the commonest pediatric neurological disorder.The incidence of seizure is highest i.e. 5% children experience seizure during the first 5 year of life, with a decreasing frequency in older age. Seizure in childhood may interfere with family and social life of parents,imposing fear and anxiety to parents.Parental response on seizure is determined by their knowledge on seizure. Objective of study:To assess the knowledge and attitude of parents towards the first seizure of their children in the Jharkhand context. Result:Maximum number of cases was in between the age of 1-5yearsi.e. 63%.Only34%consulted to their doctor after first episode. Most of the parents started to take treatment after more than two episodes of seizure i.e.89%after counselling.Only43%........

Keywords: Seizure, Knowledge, Parents, Children, Attitude, Hospital,Jharkhand

[1]. Mohamed A. Mikati and Abeer J. Hani ,Seizures in childhood. Nelson's Texbook of Pediatrics First south asia Edition vol 3 Chapter 593 Page no. 2823.
[2]. Approach to a child with seizure. Essential paediatricsGhai, vinod k paul, ArvindBagga, Eighth edition, Chapter 18, Page no. 552.
[3]. Indian guideline of epilepsy,writer-mrinalkantiroy and dhiman das , chapter-116.
[4]. International journal of science and research ISSN(online)2319-7064 index value(2013):6.14,impact factor(2013):4.438.
[5]. Paediatric oncall child health care volume 13/issue 1|January _march2016DOI: https//doi.org/10.7 199/ped.oncall.2016.8.
[6]. Flury T, Aebi C, Donati F. Febrile seizures and parental anxiety: does information help? Swis Med Wkly.2001; 131(37-38):556- 560..

Abstract: Objective: To study the effect of smoking on development and progression of nephropathy in type II diabetic and non diabetic patients and to compare the effect of smoking on progression of nephropathy in above two groups. Material and methods - It was a cross sectional study done over a period of 2 years on total 120 subjects which were divided in 4 groups of 30 subjects each, Diabetic smokers, diabetic non smokers, non diabetic smokers and non diabetic non smokers. The main parameters assayed were: blood urea, serum creatinine, urine albumin creatinine ratio (ACR ) , glomerular filtration rate (GFR) , fasting plasma glucose (FPG) and serum lipid profile. The parameters assayed in the different groups were compared .Logistic regression analysis was done to study the effect of smoking on renal function. Results: Mean difference....

[1]. Alvin C Powers. Harrrison's Principles Of Internal Medicine.(19th )edition 2015; 419: 2424-26. Mc Graw Hill.
[2]. Jose M J ,VipinVarkey. Role of smoking as a modifiable risk factor in diabetic nephropathy. Journal Of Association Of Physicians Of India 2016; Volume 64:34-7.
[3]. Rask-Madsen C, King GL. Mechanisms of Disease: endothelial dysfunction in insulin resistance and diabetes. Nat. Clin. Pract. Endocrinol. Metab. 2007;3:46–56.
[4]. Hua P, Feng W, Ji S, Raij L, Jaimes EA. Nicotine worsens the severity of nephropathy in diabetic mice: implications for the progression of kidney disease in smokers. Am J Physiol Renal Physiol. 2010;299: F732–39.
[5]. Pinto Sietsma SJ, Mulder J. Smoking is related to albuminuria and abnormal renal function in non diabetic persons. Ann Intern Med.2000;133:585-91..

Abstract: Malaria is an acute parasitic illness mainly caused by Plasmodium Vivax and Plasmodium falciparum in India. Studying its prevalence is necessary to implement effective control measures. The aim of this study was to determine three-year blood smear positive rate of malaria. A retrospective study was conducted at Government Theni medical college, Theni. Three years malaria cases data has been collected from laboratory register from the May 2012 to May 2015. Among the total 7,545 blood smears examined 3345 smears were from fever cases and examined for malaria. Of these smears 31 (0.93%) smears were positive for malaria. Among the positive smears predominant species detected was Plasmodium vivax 28 cases (90%) followed by Plasmodium falciparum 3 cases (10%). The smear positive rate of malaria in Theni district is almost constant in three years with slight fluctuation..........

Key words: Malaria, peripheral smear, plasmodium vivax, plasmodium falciparum.

[1]. Ashwani Kumar,Neena Valecha,Tanu Jain, and Aditya P. Dash.Burden of Malaria in India: Retrospective and Prospective View. Supplement to Volume 77(6) of American Journal of Tropical Medicine and Hygiene;2007 Dec
[2]. H. Rodulfo,M. De Donato, R. Mora, L. González and C.E. Contreras. Comparison of the diagnosis of malaria by microscopy, immunochromatography and PCR in endemic areas of Venezuela. Brazilian Journal of Medical and Biological Research (2007) 40: 535-543
[3]. Sushil Kumar, Roma Goyal, P.K. Jain. A Comparison of Smear versus QBC and Rapid Malaria card tests as diagnostic tool for Malarial parasites. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) Volume 16, Issue 9 Ver. IX (September. 2017), PP 41-44..

Abstract: Introduction: Crowding is the one of the most common problems motivating the patient to seek orthodontic treatment. Only few studies are available on the evaluation of the cephalometrics with mandibular crowding in the same population. The objective of this study was to compare cephalometric measurements in permanent dentition. Material and methods: It was conducted on the dental casts and lateral cephalograms of 100 subjects (40 males and 60 females) between 16 years to 25 years of age, who were divided into two groups according to the presence or absence of mandibular crowding (50 crowed and 50 non crowed). The crowded sample included those in which dental crowding of more than 1 mm was present and noncrowded sample had tooth size-arch length discrepancy between +1 to-1mm. Conclusion: We found statistically significant.........

Key words: Crowding, tooth size, arch length, cephalometric measurements

[1]. Janson G, Goizueta OEFM,Garib DG, Janson M. Relationship between maxillary and mandibular base lengths and dental crowding in patients with complete class II malocclusions. Angle Orthod 2011; 81:217-21.
[2]. Turkkahramana H, Sayina MO. Relationship between mandibular anterior crowding and lateral dentofacial morphology in early mixed dentition. Angle Orthod 2004; 74: 757-62.
[3]. Bernabe E, Castillo CED, Mirb CF. Intra-arch occlusal indicators of crowding in the permanent dentition. Am J Orthod Dentofacial Orthop 2005; 128: 220-25.
[4]. Puri N Pradhan KL, Chandna A, Sehgal V, Gupta R. Biometric study of tooth size in normal, crowded, and spaced permanent dentitions. Am J Orthod Dentofacial Orthop 2007; 132: 279, e7-279,e14.
[5]. Bolton WA. Disharmony in tooth size and its relation to the analysis and treatment of malocclusion. Angle orthod 1958; 28; 113-28.

Abstract: Introduction: Fibromatosis of mesentery are rare tumor frequently associated with Gardner syndrome. They are usually asymptomatic and are usually diagnosed post-operatively. The clinic-pathological features of these patients are retrospectively reviewed in this study. Method: Study period was August 2014 to July 2015 done at NIMS, Hyderabad in department of surgical oncology. All patient with histological proven cases of mesenteric fibrosis were included in the study.
Observation: A total of 2 patient were proved to be case of mesenteric fibrosis. Both presented with abdominal lump. CECET abdomen.....

Keywords: fibromatosis, mesentery, Gardner syndrome

[1]. Weiss SW, Goldblum JR. Fibromatosis. In: Enzinger FW, Weiss SW. Soft tissue tumors, 4th ed. St. Louis: C.V. Mosby,2001:309–346.
[2]. Li M, Cordon-Cardo C, Gerald WL, Rosai J. Desmoid fibromatosis is a clonal process. Hum Pathol. 1996;27:939–943.
[3]. Almon BA, Pajerski ME, Diaz-Cano S, Corboy K, Wolfe HJ. Aggressive fibromatosis (desmoid tumor) is a monoclonal disorder. Diagn Mol Pathol. 1997;6:98–101.

[4]. McAdam WA, Goligher JC. The occurrence of desmoids in patients with familial polyposis coli. Br J Surg. 1970 Aug;57(8):618–631. [PubMed]
[5]. Reitamo JJ, Hayry P, Nykyri E, Saxen E. The desmoid tumor. Incidence, sex, age, and anatomical distribution in the Finnish population. Am J Clin Pathol. 1982;77:665–673.

Abstract: Tripod fractures constitute ofzygomatic bone and its four articulations viz; frontal bone, maxillary bone, sphenoid bone and temporal bone. When ever a Tripod fracture happens ,one or more of these articulations are interrupted. Up to 40% of all facial fracturesfall into this category. The prominence of this bone results in high incidence of its fracture. Motor vehicle accident is the most common cause.4There are various approaches for open reduction of this fracture which include lateral eyebrow incision, sub ciliary, sub tarsal, trans conjunctival and maxillary vestibular incision. Aim: The purpose of this retrospective study was to compare one point fixation with two point fixation for isolated zmc fractures. Materials And Methods:.........

Keywords: zygomatic complex, mini Plates, Tripod fracture, one point fixation

[1]. Kim JH, Lee JH,Hong SM, Park CH .The Effectiveness of 1-Point Fixation for Zygomaticomaxillary Complex Fractures:ArchOtolaryngol Head Neck Surg. 2012;138(9):828-832
[2]. Vatsa R, Priyadarshini P, Singh ADB. Comparison of One Point Fixation Versus Two Point Fixation in the Treatment of Zygomatico Maxillary Complex Fractures. IntHealthc Res J 2018;2(9):229-234. doi: 10.26440/ihrj.v2i9.177
[3]. Chakranarayan A ,Thapliyal GK, Sinha R , Suresh Menon P. Efficacy of two point rigid internal fixation in the management of zygomatic complex fracture: J Maxillofac Oral Surg 8(3):265–269

[4]. Parashar A, Sharma R K, Makkar S .Rigid internal fixation of zygoma fractures: A comparison of two-point and three-point fixation :Indian J PlastSurg January-June 2007 Vol 40 Issue 1
[5]. Jo. T, Kim. J .An Anthropometric and Three-Dimensional Computed Tomographic Evaluation of Two-Point Fixation of Zygomatic Complex Fractures: Arch PlastSurg 2014;41:493-499.

Abstract: squamous cell carcinoma is a rare and distinctive variant of squamous cell carcinoma of the uterine cervix, which differs by histology and clinical behaviour from conventional squamous cell carcinoma .[1] Histologically, composed of papillary projections that are covered by several layers of atypical epithelial cells.[2] We are reporting a case of 65 years old female who presented with complaint of post menopausal bleeding and foul-smelling vaginal discharge since 6 months. A cervical biopsy was Performed and the histopathological examination showed malignant tumor tissue in papillary arrangement with fibrovascular core. Case is reported because of its rare incidence and its importance to differentiate from other subtypes of invasive squamous cell carcinoma.

[1]. Patil NJ, Shukla DB, Bharti M, Mehta M. Papillary squamotransitional carcinoma of cervix: a series of four cases. Int J Reprod Contracept Obstet Gynecol 2016;5:1820-2.
[2]. Witkiewcz AK, Wright TC, Ferenczy A, Ronnett BM, Kurman
[3]. RJ: Carcinoma and other tumors of the cervix. In Blaustein's
[4]. Pathology of the Female Genital Tract. 6th edition. Edited by Kurman RJ, Ellenson LH, Ronnett BM.NewYork: Springer-Verlag;2010:253–303.
[5]. Randall ME, Andersen WA, Mills SE, Kim JC: Papillary.

Abstract: Background: This study aims to monitor changes in IFN-γ, TNF-α and IL-6 serum levels in patients with tuberculous spondylitis during oral antituberculosis administration. Methods: With a observational prospective cohort study involving 27 patients with tuberculosis spondylitis treated at Saiful Anwar Hospital, Malang in January-December 2017, serum IFN-γ, TNF-α and IL-6 levels were measured by enzyme-linked immunosorbant assay (ELISA ) at the time prior to oral antituberculous therapy, and after 2 months of therapy. Assessed correlation relationship of cytokine levels change compared with clinical change after 2 months of anti tuberculosis..........

Keywords: IFN-γ, TNF-α, IL-6, tuberculous spondylitis,

[1]. Abbas A.K.,Lichtman A.H. Cellular and Molecular Immunology, 5th ED.,WB Saunders., Philadelphia.
[2]. Agrawal V, Patgaonkar PR, Nagariya SP. Tuberculosis of Spine. Journal of Craniovertebral Junction and Spine 2010, 1: 14.
[3]. Ahn JS, Lee JK. Diagnosis and Treatment of Tuberculous Spondilitis nd Pyogenic Spondilitis in Atypical Cases. Asian Spine Journal.Vol. 1, No. 2, pp 75~79, 2007.
[4]. Albar Z. Medical treatment of Spinal Tuberculosis. Cermin Dunia Kedokteran No. 137, 2002 29.
[5]. Camillo FX. Infections of the Spine. Canale ST, Beaty JH, ed. Campbell's Operative Orthopaedics. edisi ke-11. 2008. vol. 2, hal. 2237.

Abstract: Background: The burden of snakebite envenoming causing both morbidity and mortality still has a great impact on the population and on health-care systems. Hospital records fall far short of the actual number owing to dependence on traditional healers and practitioners. Objectives: Clinicoepidemilogical profiling of snake bite cases admitted in a tertiary care hospital in rural South Bengal over a period of 1 year (2016-17). Materials & Methods: Prospective hospital..........

[1]. Mulay DV, Kulkarni VA, Kulkarni SG, Kulkarni ND, Jaju RB.Clinical profile of Snakebites at SRTR Medical College Hospital, Ambajogai (Maharashtra). Indian Med Gaz. 1986;131:363-6.
[2]. Kasturiratne A, Wickremasinghe AR, de Silva N, Gunawardena NK, Pathmeswaran A, Premaratna R, et al. The global burden of snakebite: A literature analysis and modelling based on regional estimates of envenoming and deaths. PLoS Med. 2008;5(11):e218.
[3]. David AW. Guidelines for the Clinical Management of Snake-Bites in the South-East Asia Region. New Delhi: World Health Organization, Regional Office for South East Asia; 2005. p. 1-67.
[4]. Swaroop, S., and Grab, B. 1954. Snakebite mortality in the world. Bull World Health Organ 10: 35–76.
[5]. Theakston, R.D.G., Warrell, D.A., and Griffiths, E. 2003. Report of a WHO workshop on the standardization and control of antivenoms.Toxicon 41: 541–557.

Abstract: The major objectives of surgical treatment in patients with temporomandibular joint ankylosis are meticulous and radical removal of the ankylotic bone and, reconstruction and restoration of the physiologic functions of the lower jaw. A successful reconstructed temporomandibular joint should reproduce normal joint structure, provide functional articulation, and permit adaptive growth and remodeling. Difficulty in achieving the treatment goal is illustrated by the multiplicity of autologous and allogenic materials proposed or currently used to reconstruct temporomandibular joint. In 1989, Mosby and Hiatt described a new technique to securely fix the graft and therefore the dimension of gap between the rib graft and the mandible minimized while pressing the graft against the mandibular surface. In our study, we...........

[1]. Macintosh Henny, A spectrum of application of autogenous Costochondral Graft J Maxillofacial Surgery 15:257, 1977.
[2]. Miyamato, et al, The effect of partial immobilization of temporomandibular joint ankylosis reconstructed with costo chondral graft. A sheep study IJOMS 2001;39;196;203
[3]. Adekeye, E.O., Ankylosis of the mandible-Analysis of 76 cases. J Oral Maxillofacial surgery 41:422-449, 1983.
[4]. Ried et al, The Clavicular head of Pectoralis major musculo cutaneous free flap. British J. of Plast. Surg 39:57,1986
[5]. Thoma K.H, Textbook of Oral Surgery. Ed. 4 St-Louis, Cx Mosby 10, 1969..

Abstract: Fractures of the mandibular angle represent the largest percentage of mandibular fractures. Therapeutic goal of any fracture management is to restore form and function at the earliest without any morbidity. Fractures of the mandibular angle represent an important clinical challenge because their treatment is plagued with the highest post surgical complication rate of all mandibular fractures. Traditional modalities include;maxillomandibular fixation alone in favorable fracture cases and open reduction and internal fixation in unfavorable fracture cases. A number of fixation methods have been advocated for treatment of mandibular angle fractures.1 A study was done to evaluate the usefulness of two miniplate technique on patients who reported to, The Department of Oral and Maxillofacial surgery, Tamil Nadu Government Dental College and hospital, Chennai with mandibular angle fractures...........

[1]. E.Ellis III: Treatment methods for fractures of mandibular angle. Int. J. Oral Maxillofac. Surg. 1999; 28: 273-252
[2]. Michelet, et al; Osteosynthesis with miniaturized screwed plates in maxillofacial surgery. J. Maxillofacial Surg. 1973; 1: 79
[3]. Champy M: Mandibular osteosynthesis by miniature screwed plates via a buccal approach. Journal of Oral and Maxillofacial Surgery. 1978; 6: 14
[4]. Choi B.H., et al., Stability testing of a two miniplate fixation technique for mandibular angle fractures. An in vitro study. J Craniomaxillofac. Surg. 1995; 23(2): 123-5
[5]. E.Ellis., et al., Treatment of Mandibular angle fractures using two non compression miniplates. Journal of Oral and Maxillofacial Surgery. 1994; 52(10): 1032-6.

Abstract: Background- Skin warts is a fairly common condition and primarily treated with destructive method which may be associated with scarring in multiple warts. Treatment with intralesional injections has gained momentum due to its efficacy in clearing not only the local warts but also distant warts by stimulating the cell-mediated immunity against human papillomavirus. Aims- To evaluvate the safety and effectivness of intralesional Vitamin D3 for the treatment of multiple skin warts. Materials and Methods- Patients with multiple ( ˃2 in number ) skin warts were selected for immunotherapy. Intralesional Vitamin D3 (0.2 ml.........

Keywords - Warts, vitamin D3

[1]. Sterling JC, Handfield-Jones S, Hudson PM. British Association of Dermatologists. Guidelines for the management of cutaneous warts. Br J Dermatol. 2001;144:4–11
[2]. Gibbs S, Harvey I, Sterling J, Stark R. Local treatments for cutaneous warts: Systematic review. BMJ. 2002;325:461.
[3]. Bourke JF, Berth-Jones J, Hutchinson PE. Cryotherapy of common viral warts at intervals of 1, 2 and 3 weeks. Br J Dermatol. 1995;132:433–6.
[4]. Gonçalves MA, Donadi EA. Immune cellular response to HPV: Current concepts. Braz J Infect Dis. 2004;8:1–9.

[5]. Aktas H, Ergin C, Demir B, Ekiz Ö. Intralesional Vitamin D injection may be an effective treatment option for warts. J Cutan Med Surg. 2016;20:118–22.