iosr-JDMS   Volume-23 ~ Issue-3 ~ March 2024

Abstract: Background the rate of hip fractures in developing countries like ours is rising and the low socioeconomic status of our patients makes affordability of some treatment options difficult. The purpose of this study was to analyze the epidemiologic pattern of treated hip fractures. Materials and methods a single center retrospective cross sectional study conducted at abubakar tafawa-balewa university teaching hospital (atbuth),bauchi .data of 60 patients over the age of 18 years with hip fractures (femoral neck, intertrochanteric.....

Key words: epidemiologic pattern, treated, hip fractures

[1]. Schmidt Ah, Swiontkowski Mf. Femoral Neck Fractures. Orthop Clin North Am. 2002 Jan;33(1):97–111, Viii.
[2]. Daniel M, Mohammed S, Francis A, William Y, Joseph K, Cornilius E. Early Result Of Hemiarthroplasty In Elderly Patients With Fracture Neck Of Femur. Niger Med J J Niger Med Assoc. 2015 Feb;56(1):64–8.
[3]. Calder Sj, Anderson Gh, Jagger C, Harper Wm, Gregg Pj. Unipolar Or Bipolar Prosthesis For Displaced Intracapsular Hip Fracture In Octogenarians: A Randomised Prospective Study. J Bone Joint Surg Br. 1996 May;78(3):391–4.
[4]. Rogmark C, Carlsson A, Johnell O, Sernbo I. A Prospective Randomised Trial Of Internal Fixation Versus Arthroplasty For Displaced Fractures Of The Neck Of The Femur. Functional Outcome For 450 Patients At Two Years. J Bone Joint Surg Br. 2002 Mar;84(2):183–8.
[5]. Raven Tf, Friedl W, Moghaddam A. Treatment Of Traumatic Femoral Neck Fractures With An Intramedullary Nail In Osteoporotic Bones. Indian J Orthop. 2021 Jun;55(3):621–8..

Abstract: Background Caesarean hysterectomy involves the removal of the uterus during planned (elective) or emergency caesarean delivery in order to prevent maternal mortality. Factors such as the clinical state of the patient, surgery duration, regulation of haemostasis, reduction in blood loss, haemorrhage and reduction of potential postoperative adverse effects, are considered in while choosing the type of caesarean hysterectomy. Objectives.....

Key Word: Caesarean, hysterectomy, uterine rupture, subtotal hysterectomy, total hysterectomy, incidence

[1]. Durfee Rb. Evolution Of Caesarean Hysterectomy. Clin Obset Gynecol 1969;12:575.
[2]. Abdulrahim G, Fadwah T, Hassan L, Bander H, Afaf T, Musab A. Cesarean Hysterectomy: A 10-Year Retrospective Review In Jeddah, Saudi Arabia. J Gynecol Women's Health 2021;22(1):556078:1-9.
[3]. Fatima T, Qayyum Fi, Tabassum Z. Ten Years Experience And Review Of Postpartum Hysterectomy Cases In Fauji Foundation Hospital Lahore. Pjmhs 2019;13(1):37-39.
[4]. Rossi Ac, Lee Rh, Chmait Rh. Emergency Postpartum Hysterectomy For Uncontrolled Postpartum Bleeding: A Systematic Review. Obstet Gynecol 2010;115(3):637-644.
[5]. Dankhonsakul K, Aswakul O. Risk Factors For Cesarean Hysterectomy At Maharat Nakhon Ratchasima Hospital. Thai Journal Of Obstetrics And Gynaecology 2017;25:191-198.

Abstract: Background: The prevalence of obesity is rising at an astonishing rate over the last decade globally making the individual highly susceptible to various diseases. It has transformed into a major public health issues in India. These changes may reduce the compliance of the lungs and the thoracic cavity and increase the load on the respiratory muscles. This may end up with the reduction in forced expiratory volume in first second (FEV1). Aim and Objective: The aim of the study is to see the effect of body mass index (BMI) on the FEV1 in adults. Methodology: This cross sectional.....

[1]. Jones Rl1, Nzekwu Mm Effect Of Body Mass Index On Lung Volume. Chest. 2006 Sep;130(3):827-33
[2]. Ogden Cl, Carroll Md, Curtin Lr Et Al. Prevalence Of Overweight And Obesity In The United States, 1999-2004. Jama 2006;295:1549–1555.
[3]. Elmadfa I, Freisling H. Nutritional Status In Europe: Methods And Results. Nutr Rev 2009;67 Suppl 1:S130–S134.
[4]. Kelly T, Yang W, Chen Cs, Reynolds K, He J. Global Burden Of Obesity In 2005 And Projections To 2030. Int J Obes (Lond) 2008;32:1431–1437.
[5]. Kar Ss, Kar Ss. Prevention Of Childhood Obesity In India: Way Forward. J Nat Sci Biol Med 2015;6:12-7..

Abstract: Résumé L'hypertension artérielle est sans doute le facteur de risque le plus incriminé à l'origine des désordres pouvant toucher le cerveau qu'elles soient vasculaires ou dégénératives. Compromettant ainsi le pronostic vital et fonctionnel (accidents vasculaires cérébraux et démences). Souvent méconnue « le mal silencieux », hélas le diagnostic n'est fait qu'au stade de complications Afin d'éviter ses répercussions fatales une prise en charge précoce et adaptée est plus que nécessaire..

[1]. Enquete Stepwise Algerie 2016-2017 : Meilleure Connaissance Du Profil De Sante Des Algeriens Pour Les Facteurs De Risque Des Maladies Non Transmissibles
[2]. Edvinsson L, Mackenzie Et, Mcculloch J (1993) Autoregulation.Arterial And Intracranial Pressure. In:Edvinsson L, Mackenzie Et Mcculloch J, Editors. Cerebral Blood Flow And Metabolism. New-York: Raven Press, 553-580.
[3]. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-Specific Relevance Of Usual Blood Pressure To Vascular Mortality: A Meta-Analysis Of Individual Data For One Million Adults In 61 Prospective Studies. Lancet 2002;360:1903-13.
[4]. Rothwell Pm. Limitations Of The Usual Blood-Pressure Hypothesis And Importance Of Variability, Instability, And Episodic Hypertension. Lancet 2010;375:938-48.
[5]. Rothwell Pm, Howard Sc, Dolan E, O'brien E, Dobson Je, Dahlöf B, Et Al. Prognostic Significance Of Visit-To-Visit Variability, Maximum Systolic Blood Pressure, And Episodic Hypertension. Lancet 2010;375: 895-905.

Abstract: Résumé Les accidents vasculaires cérébraux (AVC) sont responsables d'une morbi-mortalité élevée, d'où l'importance d'une prise en charge optimale et rigoureuse aussi bien à la phase aigüe par les traitements spécifiques (thrombolyse et thrombectomie) quand cela est possible, qu'à la phase subaigüe et au-delà par une prévention secondaire ayant pour buts le contrôle des facteurs de risque(HTA, Diabète, Dyslipidémie, Tabagisme, Obésité…

[1]. Chen Zm, Sandercock P, Pan Hc, Et Al. Indications For Early Aspirin Use In Acute Ischemic Stroke: A Combined Analysis Of 40 000 Randomized Patients From The Chinese Acute Stroke Trial And The International Stroke Trial. On Behalf Of The Cast And Ist Collaborative Groups. Stroke 2000;31:1240-9.
[2]. Antithrombotic Trialists Coll. Baigent C, Blackwell L, Et Al. Aspirin In The Primary And Secondary Prevention Of Vascular Disease: Collaborative Meta-Analysis Of Individual Participant Data From Randomised Trials. Lancet 2009;373:1849-60.
[3]. Antithrombotic Trialists Collaboration, Baigent C, Blackwell L, Et Al. Aspirin In The Primary And Secondary Prevention Of Vascular Disease : Collaborative Meta-Analysis Of Individual Participant Data From Randomised Trials. Lancet 2009;373:1849-60.
[4]. Cucchiara Bl, Messe Sr. Antiplatelet Therapy For Secondary Prevention Of Stroke. In: Post Tw. Waltham: Ed. Uptodate,, 2016.

Abstract: Summary The term acute myelopathy refers to an impairment of the spinal cord, the origin of which can be infectious, inflammatory, toxic, paraneoplastic, or idiopathic, with onset occurring within a few hours. According to some authors, myelopathy is considered acute when the onset occurs between 4 hours and 3 weeks (1). Vascular myelopathies, characterized by hyper-acute onset (< 4 hours), should be distinguished. Clinically, the presentation depends on the etiology....

[1]. Transverse Myelitis Consortium Working Group. Proposed Diagnostic Criteria And Nosology Of Acute Transverse Myelitis. Neurology 2002;59:499–505.
[2]. Scott Tf. Nosology Of Idiopathic Transverse Myelitis Syndromes. Acta Neurol Scand 2007;115:371–6.
[3]. Collongues N, Kremer S, De Sèze J. Myélopathies Aiguës. Emc - Neurologie 2017;14(1):1-14 [Article 17-071-A-10].
[4]. R. Marignier. Acute And Subacute Myelopathy , Revue Neurologique 177 (2021) 557-566
[5]. Berger Jr. Infectious Myelopathies. Continuum 2011;17:761–75..

Abstract: The sequentially damaging alterations in the oral cavity's hard and soft tissues that occur in individuals who require a single repair of an entirely edentulous arch in opposition to a natural dentition were jointly referred to as combination syndrome by kelly in 1972. Prosthodontists attempt to cure this combination condition with meticulous preparation for treatments. Utilising therapeutic, preventive, and functional treatment modalities that may call for a multidisciplinary approach involving surgical intervention....

Keywords : combination syndrome, single completely edentulous arch, flabby tissue

[1]. Kelly E. Changes Caused By A Mandibular Removable Partial Denture Opposing A Maxillary Complete Denture. The Journal Of Prosthetic Dentistry 1972;27(2):140-50.
[2]. Palmqvist S, Carlsson G. The Combination Syndrome: A Literature Review. The Journal Of Prosthetic Dentistry 2003;90(3):270-5.
[3]. Anumeha Narwalet Al. Prosthodontic Management Of A Patient With Combination Syndrome: A Clinical Case Repor.T Int J Advre.S2015; 4(12):509-13.
[4]. Langer Y, Laufer Bz, Cardash Hs. Modalities Of Treatment For The Combination Syndrome. J Prosthodont. 1995; 4(2):76–81.
[5]. Jyoti N, Shah N, Karthik Mm. Prosthodontic Rehabilitation Of Patients With Combination Syndrome. International Journal Of Dental Clinics. 2010 Jun 28;2(3)..

Abstract: The science of medications is called pharmacology. The primary active ingredient in a medication used for diagnosis, treatment, or prevention is called a drug. The study concerning the way chemicals (drugs) given exogenously interact with living organisms is known as pharmacology. The two primary areas of concern are how pharmaceuticals affect biological systems and how biological systems affect the effectiveness and metabolism of drugs. As a dental specialty that treats patients of all ages, especially the geriatric population, prosthodontics emphasizes the importance of understanding the local and systemic effects as well as the adverse effects of medications. The purpose of this article is to impart drug-related knowledge which is crucial while prescribing medications in a more knowledgeable way. In prosthodontics, pharmacology is one of the most overlooked areas and is usually ignored by general practitioners; consequently, more research and studies must be performed in this domain.

Key words: pharmacology, retraction cord, salivary substitute, xerostomia

[1]. Jagadeeshwaran Ar, Arora D, Kumar Va, Kumar Gr, Balamurugan T, Prabu Ps. Pharmaco-Prosthodontics Revisited. Journal Of Pharmacy & Bioallied Sciences. 2012 Aug;4(Suppl 2):S338.
[2]. Singh Gp, Soni Vk, Nehra S. Pharmacotherapeutics In Prosthodontics–An Overview. Asian Journal Of Pharmaceutical Research And Development. 2021 Apr 19;9(2):87-9.
[3]. Felpel Lp. A Review Of Pharmacotherapeutics For Prosthetic Dentistry: Part I. The Journal Of Prosthetic Dentistry. 1997 Mar 1;77(3):285-92.
[4]. Felpel Lp. A Review Of Pharmacotherapeutics For Prosthetic Dentistry: Part Ii. The Journal Of Prosthetic Dentistry. 1997 Mar 1;77(3):293-305.
[5]. Ahmad N, Yunus N, Jafri Z. Etiology And Management Of Gag Reflex In The Prosthodontic Clinic: A Review. Int J Oral Health Dent. 2015 Jan;1(1):25-8..

Abstract: Myiasis, an infestation by dipteran fly larvae, is common in tropical regions, affecting animals and occasionally humans in unhygienic conditions. This article reports a rare case of umbilical cord myiasis in an 8-day-old neonate from a rural area, causing sepsis. The larvae were successfully removed after applying ether to the umbilical stump. This case highlights the importance of hygiene to prevent such rare and avoidable conditions.

Keywords: Myiasis, Umbilical Cord, Neonate, Sepsis, Hygiene

[1]. Pampiglione S, Fioravanti Ml, Gustinelli A, Onore G, Mantovani B, Luchetti A, Trentini M. Human Urogenital Myiasis Due To Psychoda Spp. Larvae In Italy: A Case Report. Bmc Infect Dis. 2008 Dec;8(1):1-4.
[2]. Francesconi F, Lupi O. Myiasis. Clin Microbiol Rev. 2012 Jul;25(1):79-105.
[3]. Carvalho L, Linardi Pm, Filho Jd. Notes On The Bionomics Of Chrysomya Megacephala (Fabricius) (Diptera: Calliphoridae) In Different Environments. Mem Inst Oswaldo Cruz. 1990 Sep;85(3):331-6.
[4]. Vonarx Vj. A Case Of Cutaneous Myiasis Due To Dermatobia Hominis. Clin Infect Dis. 1995 Jul;21(1):193-4.
[5]. Hall Mjr, Wall Rl, Stevens Jr. Traumatic Myiasis: A Neglected Disease In A Changing World. Annu Rev Entomol. 2016 Jan;61:159-76..

Abstract: Résumé L'hématome du plancher buccal est une complication rare observée en cas de troubles de la coagulation, de traumatismes, d'interventions dentaires et d'utilisation d'anticoagulants. Seules quelques publications ont décrit des hématomes du plancher buccal spontanés idiopathiques, et toutes ont suspecté une hypertension sévère comme étiologie. Notre objectif est de présenter un cas d'hématome du plancher buccal spontané idiopathique chez une patiente de 72 ans, sans antécédents médicaux d'hypertension et de diabète, sous antivitamines K pour une fibrillation auriculaire......

[1]. Lepore Ml (1976) Upper Airway Obstruction Induced By Warfarin Sodium. Arch Otolaryngol 102(8):505–506
[2]. Zacharia Gs, Kandiyil S, Thomas V (2014) Pseudo-Ludwig's Phenomenon:A Rare Clinical Manifestation In Liver Cirrhosis. Acg Case Rep J 2(1):53–54
[3]. Prepageran N, Raman R, Ismail Sm, Rahman Zaa (2002) Spontaneous Sublingual Hematoma As A Complication Of Severe Hypertension: First Report Of A Case. Ear Nose Throat J 81(8):576–578
[4]. Satpathy S, Guha R, Satpathy A, Guha P (2015) Spontaneous Sublingual Space Hematoma Secondary To Hypertension: A Case Report And Review Of Literature. Natl J Maxillofac Surg 6(1):96–98
[5]. Gupta Mk,Mcclymontlg,Hakimhel.Case Of Sublingualhematomathreateningairway Obstruction. Medscimonit2003;9:Cs95–Nbs.
[6]. Reillypiccinra.Médicamentsutilisésdansles Troublesdelacoagulation.Pharmacologiefon- Damentaleetclinique.7e Ed. 2000;P.570–4...

Abstract: Summary: Fractures of the distal radius are very common and pose a public health problem. Their management represents a real challenge. We conducted a prospective descriptive study. Two hundred and six patients, including four with bilateral involvement, were included in our study, which thus comprises 210 cases. Ninety percent of our patients consulted us urgently, the most frequent mechanism being indirect impact by a fall on the hyperextended.....

Keywords: distal radius fractures, Intrafocal cross-pinning HK2, osteoporosis, prospective and descriptive study.

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Abstract: Background: Breast surgery is a common procedure and is associated with an increased incidence of acute and chronic pain in almost 25-60% cases. Regional anaesthesia technique may improve post operative analgesia for patients undergoing breast surgeries. Aims and Ohbjectives: This study is aimed to compare the efficacy and safety of a landmark guided PEC I and PEC II versus thoracic paravertebral block for post operative analgesia after breast surgeries. Materials and Methods: The present study was conducted on 60 ASA grade I and II female patients with age between 18-65 years scheduled.......

Keywords: Paravertebral block, pectoral nerve block I, pectoral nerve block II, analgesia

[1]. Klein Sa, Bergh A, Steele Sm, Georgiade Gs, Greengrass Ra. Thoracic Paravertebral Block For Breast Surgery. 2000 Jun 1;90(6):1402–5.
[2]. Eun Jin Moon, Seung Beom Kim, Jun Young Chung, Jeong Yoon Song, Jae Woo Yi. Pectoral Nerve Block (Pecs Block) With Sedation For Breast Conserving Surgery Without General Anesthesia. 2017 Jan 1;93(3):166–6.
[3]. Gärtner R, Jensen Mb, Nielsen J, Ewertz M, Kroman N, Kehlet H. Prevalence Of And Factors Associated With Persistent Pain Following Breast Cancer Surgery. Jama. 2009 Nov 11;302(18):1985.
[4]. Lynch Ep, Welch Kj, Carabuena Jm, Eberlein Tj. Thoracic Epidural Anesthesia Improves Outcome After Breast Surgery. Annals Of Surgery. 1995 Nov;222(5):663–9.
[5]. Blanco R, Fajardo M, Parras Maldonado T. Ultrasound Description Of Pecs Ii (Modified Pecs I): A Novel Approach To Breast Surgery. Revista Española De Anestesiología Y Reanimación. 2012 Nov;59(9):470–5.

Abstract: Dental trauma is such a situation wherein the patient is affected both socially and psychologically. During their first dental visit, these patients with trauma are in pain and need emergency treatment. Such patients are quite apprehensive because of impaired functions, esthetics, and phonetics. The prime objective while handling such cases is successful pain management with immediate restoration of function, esthetics, and phonetics. The advances in adhesive dentistry have allowed dentists to use the patient's own fragment to restore the fractured tooth. Reattachment is such an ultraconservative technique which provides safe, fast, and esthetically pleasing results. This paper discusses fragment reattachment technique and presents a clinical case of complicated crown fracture.

Keywords – Dental trauma, Fractured fragment re-attachment, Conservative technique, Esthetics

[1]. American Academy Of Pediatric Dentistry Council On Clinical Affairs, "Guidelines On Management Of Acute Dental Trauma," Pediatric Dentistry, Vol. 30, Pp. 175–183, 2008-2009.
[2]. P. C. S. Filho, P. S. Quagliatto, P. C. Simamoto Jr., And C. J. Soares, "Dental Trauma: Restorative Procedures Using Composite Resin And Mouthguards For Prevention," Journal Of Contemporary Dental Practice, Vol. 8, No. 6, Pp. 89–95, 2007.
[3]. C. M. Forsberg And G. Tedestam, "Etiological And Predisposing Factors Related To Traumatic Injuries To Permanent Teeth," Swedish Dental Journal, Vol. 17, No. 5, Pp. 183–190, 1993.
[4]. Textbook And Color Atlas Of Traumatic Injuries To The Teeth, Andreasen J. O., Andreasen F. M., Andersson L., Eds., Blackwell Munksgaard, Copenhagen, Denmark, 4th Edition, 2007. [5] J. C. M. Castro, W. R. Poi, T. M. Manfrin, And L. G. Zina, "Analysis Of The Crown Fractures And Crown-Root Fractures Due To Dental Trauma Assisted By The Integrated Clinic From 1992 To 2002," Dental Traumatology, Vol. 21, No. 3, Pp. 121–126, 2005.
[5]. T. N. Tennery, "The Fractured Tooth Reunited Using The Acid-Etch Bonding Technique," Texas Dental Journal, Vol. 96, No. 8, Pp. 16– 17, 1988.

Abstract: Purpose: To report the factors influencing eye donation among families of successful eye donors in India. Methods: The consenting family members of 100 deceased individuals who donated eyes between April 2022 and March 2023 were retrospectively interviewed via a telephonic questionnaire survey. Details regarding the donors and their families, motivating factors for eye donation, and time taken for tissue recovery were collected and analyzed. Results:.......

[1]. Oliva Ms, Schottman T, Gulati M Turning The Tide Of Corneal Blindness Indian J Ophthalmol 2012 60 423 7
[2]. Gupta N, Tandon R, Gupta Sk, Sreenivas V, Vashist P Burden Of Corneal Blindness In India Indian J Community Med 2013 38 198 206
[3]. Gain P, Jullienne R, He Z, Aldossary M, Acquart S, Cognasse F, Et Al. Global Survey Of Corneal Transplantation And Eye Banking Jama Ophthalmol 2016 134 167 73
[4]. Gupta N, Vashist P, Ganger A, Tandon R, Gupta Sk Eye Donation And Eye Banking In India Natl Med J India 2018 31 283 6
[5]. Williams Am, Muir Kw Awareness And Attitudes Toward Corneal Donation:Challenges And Opportunities Clin Ophthalmol 2018 12 1049 59.

Abstract: Dystonia, a neurological disorder characterized by abnormal and involuntary muscle movements, encompasses a complex interplay of genetic, environmental, and neurochemical factors. This article provides a comprehensive overview of the etiology, pathophysiology, and therapeutic implications of dystonia. Genetic influences, neurotransmitter dysregulation, brain circuitry abnormalities, environmental triggers, neuroinflammation, neuroplasticity, oxidative stress, metabolic factors, and hormonal influences are explored. Understanding these multifaceted dimensions of dystonia is crucial for developing targeted therapeutic interventions.

Keywords – Dystonia, Neurotransmitter Dysregulation, Neuroinflammation

[1]. Breakefield Xo, Blood Aj, Li Y, Hallett M, Hanson Pi. The Pathophysiological Basis Of Dystonias. Nat Rev Neurosci. 2008;9(3):222-234.
[2]. Albanese A, Bhatia K, Bressman Sb, Et Al. Phenomenology And Classification Of Dystonia: A Consensus Update. Mov Disord. 2013;28(7):863-873.
[3]. Klein C, Fahn S. Translation Of Dystonia Genetics To Clinical Practice. Mov Disord. 2013;28(7):754-766.
[4]. Neychev Vk, Gross Re, Lehericy S, Hess Ej, Jinnah Ha. The Functional Neuroanatomy Of Dystonia. Neurobiol Dis. 2011;42(2):185-201.
[5]. Quartarone A, Morgante F, Sant'angelo A. Pathophysiology Of Dystonia: The Role Of The Cerebellum. Front Neurol. 2020;11:182

Abstract: Background: The extraction and characterizations of α-cellulose from rice straw and wheat straw as well as synthesis of cellulose acetate from the extracted α-cellulose by trans-esterification reaction process. Cellulose acetate was synthesized from the extracted α-cellulose following by trans-esterification reaction. The synthesized cellulose acetate was analyzed by Fourier Transform Infrared Spectroscopy (FTIR) and chemical methods. FTIR spectrometry confirmed the synthesis of cellulose acetate i.e. acetylation of cellulose. Degree of acetylation and degree of substitution of the synthesized cellulose acetates were determined by a chemical method.......

Keywords – α-cellulose, trans-esterification, FTIR, Rice straw and Wheat straw

[1]. Han JS. Chemical composition of fibers. Paper and composites from agrobased resources. 1997:83-134
[2]. Lu X, Zhang MQ, Rong MZ, Shi G, Yang GC. Self-reinforced melt processable composites of sisal. Composites science and technology. 2003 Feb 1;63(2):177-86
[3]. Heinze T, Liebert T. Unconventional methods in cellulose functionalization. Progress in polymer science. 2001 Nov 1; 26(9):1689-762.
[4]. Chowdhury MA, Hassan MS. Hand book of agricultural technology. Bangladesh Agricultural Research Council, Farmgate, Dhaka. 2013 May; 230.
[5]. Jin S, Chen H. Near-infrared analysis of the chemical composition of rice straw. Industrial Crops and Products. 2007 Aug 1; 26(2):207-11.

Abstract: Background: The pain following major surgery results in delay in the postoperative recovery of patients after operation, longer hospitalization period, excess use of analgesics and it is very frustrating for both surgery and anesthesia. One of the methods for controlling postoperative pain is preemptive analgesia. Preemptive analgesia is defined as a treatment that is initiated before surgery in order to prevent the establishment of central sensitization evoked by the incisional and inflammatory injuries occurring during surgery and in the early postoperative......

Keywords – Preemptive analgesia, Diclofenac sodium, Non-steroidal anti-inflammatory drugs (NSAID).

[1]. Vadivelu N, Mitra S, Schermer E, Kodumudi V, Kaye AD, Urman RD. Preventive analgesia for postoperative pain control: a broader concept. Local and regional anesthesia. 2014 May 29:17-22.
[2]. Gottschalk A, Smith DS. New concepts in acute pain therapy: preemptive analgesia. American family physician. 2001 May 15;63(10):1979-85.
[3]. Hariharan S, Moseley H, Kumar A, Raju S. The effect of preemptive analgesia in postoperative pain relief—a prospective double-blind randomized study. Pain medicine. 2009 Jan 1;10(1):49-53.
[4]. Ong CK, Lirk P, Seymour RA, Jenkins BJ. The efficacy of preemptive analgesia for acute postoperative pain management: a meta-analysis. Anesthesia & Analgesia. 2005 Mar 1;100(3):757-73.
[5]. Chandrasekaran S, Nanivadekar AC, McKernan GP, Helm ER, Boninger ML, Collinger JL, Gaunt RA, Fisher LE. Sensory restoration by epidural stimulation of dorsal spinal cord in upper-limb amputees. medRxiv. 2019 Oct 22:19009811

Abstract: Background: The administration of analgesics and sedatives are vital for mechanically ventilated patients for providing comfort and reducing stress, as well as to prevent delay in recovery and ventilator weaning. Hypnotic based regime using midazolam-fentanyl combination is commonly used for sedation and analgesia in intensive care unit. The hypnotic component is titrated to a desired level of consciousness and analgesia given as per thought of physicians. Objectives: This study was conducted to explore effectiveness of remifentanil for optimum sedation and analgesia in comparison to midazolam-fentanyl combination in mechanically ventilated patients. Methods: The.......

Keywords –Analgesic, Sedative, Ventilated patients, Midazolam-fentanyl

[1]. Ostermann ME, Keenan SP, Seiferling RA, Sibbald WJ. Sedation in the intensive care unit: a systematic review. Jama. 2000 Mar 15;283(11):1451-9.
[2]. Grounds RM, Lalor JM, Lumley J, Royston D, Morgan M. Propofol infusion for sedation in the intensive care unit: preliminary report. British Medical Journal (Clinical research ed.). 1987 Feb 2;294(6569):397.
[3]. Pearson SD, Patel BK. Evolving targets for sedation during mechanical ventilation. Current opinion in critical care. 2020 Feb;26(1):47.
[4]. Olkkola KT, Ahonen J. Midazolam and other benzodiazepines. Modern anesthetics. 2008 Jan 1:335-60.
[5]. Obata Y, Adachi YU, Suzuki K, Itagaki T, Kato H, Satomoto M, Nakajima Y. The influence of differences in solvents and concentration on the efficacy of propofol at induction of anesthesia. Anesthesiology Research and Practice. 2016 Jan 21;2016.

Abstract: Background: A precancerous cervical lesion is a variation in the cervix's cells that has the potential to progress to cervical cancer. One public health issue that adds to women's deaths globally is cervical cancer. Cervical cancer is the leading cause of death in women. Worldwide, cervical cancer is the fourth leading cause of death in women. Objective: The aim of this study is to evaluate the impact of cervical precancerous lesion by histopathology. Methods: The cross-sectional observational study was conducted in the Department of Colposcopy Clinic of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, from January 2022 to December 2022. A total......

Keywords –Cervical Precancerous Lesions, Histopathology

[1]. FMoH. National cancer control plan 2016–2020. Addis Ababa; 2015.
[2]. World Health Organization, Programme on Cancer Control (World Health Organization), World Health Organization. Reproductive health. In: Cervical cancer screening in developing countries: Report of a WHO consultation. World Health Organization; 2002.
[3]. Teka T, Kote M, Kejela G, Getachew T. Magnitude and factors associated with precervical cancer among screened women in Southern Ethiopia. Advances in Public Health. 2019; 23:2019-2028.
[4]. Tekle T, Wolka E, Nega B, Kumma WP, Koyira MM. Knowledge, attitude and practice towards cervical cancer screening among women and associated factors in hospitals of Wolaita Zone, Southern Ethiopia. Cancer Manag Res. 2020;12: 993-1005.
[5]. Ferlay JS, Soerjomataram I, Ervik M, Dikshit R, Eser S, Mathers C, Rebelo M, Parkin DM, Forman D, Bray F. GLOBOCAN 2012 v1. 0. Cancer incidence and mortality worldwide: IARC Cancer Base. 2013; 11. DOI: 10.1002/ijc.29210