iosr-JDMS   Volume-23 ~ Issue-4 ~ April 2024

Abstract: Background: Oral manifestations can be used to detect a range of systemic disorders. Gingival enlargement can occur owing to local circumstances, drugs, hormonal changes, or malignant disorders. Dental surgeons must accurately diagnose and refer patients with leukemia, a malignancy characterized by abnormal white blood cell proliferation in the bone marrow. Oral changes may be the only presenting feature, making timely diagnosis and referral crucial to avoid fatal outcomes. This article discusses a case of acute myeloid leukemia (AML) characterized by swollen gums for...

[1] Hasan S, Khan Ni, Reddy Lb. Leukemic Gingival Enlargement: Report Of A Rare Case With Review Of Literature. Int J Appl Basic Med Res. 2015 Jan-Apr;5(1):65-7. Doi: 10.4103/2229-516x.149251. Pmid: 25664273; Pmcid: Pmc4318106.
[2] Chowdhri K, Tandon S, Lamba Ak, Faraz F. Leukemic Gingival Enlargement: A Case Report And Review Of Literature. J Oral Maxillofac Pathol. 2018 Jan;22(Suppl 1):S77-S81. Doi: 10.4103/Jomfp.Jomfp_205_17. Pmid: 29491612; Pmcid: Pmc5824525.
[3] Menezes L, Rao Jr. Acute Myelomonocytic Leukemia Presenting With Gingival Enlargement As The Only Clinical Manifestation. J Indian Soc Periodontol. 2012;16:597–601.
[4] Carranza Fa, Hogan El. Gingival Enlargement. In: Newman Mg, Takei Hh, Carranza Fa, Editors. Clinical Periodontology. 10th Ed. Philadelphia: Wb Saunders Co; 2002. Pp. 279–96.
[5] Demirer S, Ozdemir H, Sencan M, Marakoglu I. Gingival Hyperplasia As An Early Diagnostic Oral Manifestation In Acute Monocytic Leukemia: A Case Report. Eur J Dent. 2007;1:111–4

Abstract: A sixteen year old boy was presented with esthetic concerns in his upper anterior teeth. On clinical examination both the maxillary central incisor revealed fracture of the crown. Radiographic evaluation revealed open apex of both central incisors. Apexification with Biodentine was carried out in two different methods as bioroot inlay and thermoplastized condensation. In six months follow up both the tooth were clinically and radiographically asymptomatic

Keywords: Open apex, Trauma, Apexification, Bioroot inlay, Thermoplastized condensation, Biodentine

[1] Ravindran V, Jeevanandan G, Marimuthu M, Et Al. Comparison Of Mineral Trioxide Aggregate And Biodentine For Open Apex Management In Children With Nonvital Immature Permanent Teeth: A Systematic Review. European Journal Of General Dentistry. 2022;11(2):84-93
[2] Andreasen Jo, Ravn Jj. Epidemiology Of Traumatic Dental Injuries To Primary And Permanent Teeth In A Danish Population Sample, Int J Oral Surg 1972;1: 235.
[3] Bastone Eb, Freer Tj, Mcnamara Jr. Epidemiology Of Dental Trauma: A Review Of The Literature, Aust Dent J 2000;45: 2.
[4] Ravindranath Megha1 , Newbegin Selvakumar Gold Pearlin Mary2 , Arumugam Karthick3 , Paramasivam Vivekanandhan3. (2020). Diagnosis And Treatment Modalities Of Open Apex – A Review. Indian Journal Of Forensic Medicine & Toxicology, 14(4), 1380–1384.
[5] Villat C, Grosgogeat B, Seux D, Farge P. Conservative Approach Of A Symptomatic Carious Immature Permanent Tooth Using A Tricalcium Silicate Cement (Biodentine): A Case Report. Restor Dent Endod. 2013;38(4):258–62. Doi:10.5395/Rde.2013.38.4.258.

Abstract: Background: Anemia is a prevalent blood condition resulting from decreased red blood cells (RBCs), also called the RBC count or haemoglobin (Hb) concentration of the peripheral blood, below the normal level in proportion to age and sex. Anemia is prevalent in every age group and gender. Around one-third of people worldwide have anemia, which is a big public health problem affecting 1·62 billion people worldwide. It is estimated that anemia causes 5, 91,000 neonatal deaths and about 1, 15,000 maternal deaths worldwide each year.....

Keywords: anemia, morphological patterns of anemia, microcytic anemia, normocytic anemia, macrocytic anemia, hypochromic anemia, normochromic anemia, causes of anemia, treatment of anemia in a tertiary care unit

[1] King, Tc. Hematopoietic Pathology. In: Elsevier's Integrated Pathology. Philadelphia (Pa): Mosby Elsevier; 2007. Pp. 263-289.
[2] Mclean E, Cogswell M, Egli I, Wojdyla D, De Benoist B. Worldwide Prevalence Of Anemia, Who Vitamin And Mineral Nutrition Information System, 1993–2005. Public Health Nutra 2009; 12: 444–54.
[3] Mclean E, Cogswell M, Egli I, Wojdyla D, De Benoist B. Worldwide Prevalence Of Anemia, Who Vitamin And Mineral Nutrition Information System, 1993–2005. Public Health Nutr 2009; 12: 444–54.
[4]
Mclean E, Cogswell M, Egli I, Wojdyla D, De Benoist B. Worldwide Prevalence Of Anemia, Who Vitamin And Mineral Nutrition Information System, 1993–2005. Public Health Nutr 2009; 12: 444–54.
[5] Mclean E, Cogswell M, Egli I, Wojdyla D, De Benoist B. Worldwide Prevalence Of Anemia, Who Vitamin And Mineral Nutrition Information System, 1993–2005. Public Health Nutr 2009; 12: 444–54.

Abstract: This case report discusses the management of Grade III Oral Submucous Fibrosis (OSMF), a debilitating condition prevalent in the Indian subcontinent, characterized by oral mucosal stiffness and functional limitations, often associated with areca nut chewing. The patient, a 26-year-old male, presented with difficulty in mouth opening due to OSMF. Conservative treatment involving intralesional injections of placental extract, hyaluronidase, and dexamethasone, along with adjuvant therapy including lycopene supplementation and physiotherapy, was administered.....

Keywords: Oral Submucous Fibrosis, Intralesional Injections, Placental Extract, dexamethasone

[1] More Cb, Rao Nr. Proposed Clinical Definition For Oral Submucous Fibrosis. J Oral Biol Craniofac Res. 2019;9(4):311-314. Doi:10.1016/J.Jobcr.2019.06.016
[2] Shih Yh, Wang Th, Shieh Tm, Tseng Yh. Oral Submucous Fibrosis: A Review On Etiopathogenesis, Diagnosis, And Therapy. Int J Mol Sci. 2019;20(12):2940. Published 2019 Jun 16. Doi:10.3390/Ijms20122940
[3] Hazarey Vk, Erlewad Dm, Mundhe Ka, Ughade Sn. Oral Submucous Fibrosis: Study Of 1000 Cases From Central India. J Oral Pathol Med. 2007;36(1):12–7.
[4] Hazarey Vk, Erlewad Dm, Mundhe Ka, Ughade Sn. Oral Submucous Fibrosis: Study Of 1000 Cases From Central India. J Oral Pathol Med. 2007;36(1):12–7.
[5] Wollina U, Verma Sb, Ali Fm, Patil K. Oral Submucous Fibrosis: An Update. Clin Cosmet Investig Dermatol. 2015;8:193-204. Published 2015 Apr 13. Doi:10.2147/Ccid.S80576.

Abstract: Neuroendocrine small cell carcinomas are most commonly seen in the lung and they rarely aries in the extrapulmonary sites. Small cell carcinoma of tongue is an extremely rare entity with only eight cases reported till date.A50 years old male presented with left side neck swelling proliferative growth at the base of tongue Histopathologically and immunohistochemistry confirmed as a small cell carcinoma of base of tongue. We discuss clinical, pathological, radiological finding and management of small cell carcinoma of base of tongue. These are all important for the correct diagnosis of small cell carcinoma. As no standard therapeutic regimen exists for extrapulmonary SCC .The patient was treated with combination of chemotherapy and radiotherapy.

Keywords: Extrapulmonary SCC, Base of Tongue

[1]. Globocon 2020 The Global Cancer Observatory
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[4]. Kim Ko, Lee Hy, Chun Sh, Shin Sj, Kim Mk, Et Al. (2006) Clinical Overview Of Extra Pulmonary Small Cell Carcinoma. J Korean Med Sci 21: 833-837.

Abstract: Porcelain laminate veneers have emerged as a popular choice in cosmetic dentistry, offering a blend of aesthetic appeal and functional durability. This case series presents two distinct clinical scenarios where porcelain laminate veneers were employed to address aesthetic concerns and restore dental integrity. Case 1: A 32-year-old female presented with chipped front teeth, affecting her smile aesthetics. Following a comprehensive diagnostic process, including history, examination, and shade selection, the patient underwent the placement of three porcelain...

Keywords: Porcelain laminate veneer, laminate bonding, bonding, emax

[1] .Turgut S, Bagis B. Colour Stability Of Laminate Veneers: An In Vitro Study. J Dent. 2011 Dec;39 Suppl 3:E57- 64. Doi: 10.1016/J.Jdent.2011.11.006. Epub 2011 Nov 12. Pmid: 22101122
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[3] Calamia Jr, Simonsen Rj. Effect Of Coupling Agents On Bond Strength Of Etched Porcelain. J Dent Res 1984;63:162–362.
[4] Kugel G, Ferreira S. The Art And Science Of Tooth Whitening. J Mass Dent Soc. 2005;53(4):34–7.
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Abstract: Background: Dengue (break-bone fever) is a vector-borne viral disease caused by the dengue virus (DENV) spreads through the infected female mosquito bite. Aedes aegypti mosquito act as vector in transmitting the disease to humans. The dengue virus initially replicates in the mosquito midgut later disseminate to secondary tissues, including the salivary glands. Diabetes Mellitus has been significantly linked to chronic inflammation is unambiguous. Our study aims to compare the severity of dengue infection among diabetic and non-diabetic populations in JSS hospital, Mysuru, Karnataka.....

Keywords: Dengue virus; Diabetic; Thrombocytopenia; Leucopenia; Immunopathogenesis

[1] Jentes, E. S., Lash, R. R., Johansson, M. A., Sharp, T. M., Henry, R., Brady, O. J., ... & Brunette, G. W. (2016). Evidence-Based Risk Assessment And Communication: A New Global Dengue-Risk Map For Travellers And Clinicians#. Journal Of Travel Medicine, 23(6), Taw062.
[2] Gould, E. A. (1998). Dengue Haemorrhagic Fever: Diagnosis, Treatment, Prevention And Control-. Geneva: World Health Organization, 1997. Vii+ 84pp. Price Sw. Fr. 26/Us $23.40 (In Developing Countries Sw. Fr. 18.20) Isbn 92-4-154500-3. Available In English; French Version In Preparation. Transactions Of The Royal Society Of Tropical Medicine And Hygiene, 4(92), 470.
[3] Lee, K., Hsieh, C. J., Lee, C. T., & Liu, J. W. (2020). Diabetic Patients Suffering Dengue Are At Risk For Development Of Dengue Shock Syndrome/Severe Dengue: Emphasizing The Impacts Of Co-Existing Comorbidity (Ies) And Glycemic Control On Dengue Severity. Journal Of Microbiology, Immunology And Infection, 53(1), 69-78.
[4] Singh, R., Goyal, S., Aggarwal, N., Mehta, S., Kumari, P., Singh, V., ... & Emran, T. B. (2022). Study On Dengue Severity In Diabetic And Non-Diabetic Population Of Tertiary Care Hospital By Assessing Inflammatory Indicators. Annals Of Medicine And Surgery, 82, 104710.
[5] Kalayanarooj, S., Vaughn, D. W., Nimmannitya, S., Green, S., Suntayakorn, S., Kunentrasai, N., ... & Ennis, F. A. (1997). Early Clinical And Laboratory Indicators Of Acute Dengue Illness. Journal Of Infectious Diseases, 176(2), 313-321.

Abstract: Caroli's disease, a rare congenital condition, among the ductal plate malformations characterized by non-obstructive saccular or fusiform dilatation of larger intrahepatic bile ducts that occur at different levels in the developing biliary tree. The disease is also characterized by the formation of intraductal calculi and susceptibility to infection. It as an autosomal recessive disease which is often associated with congenital hepatic fibrosis & autosomal...

Keywords: Caroli disease, USG (Ultrasonography), CT scan

[1] Caroli J, Soupault R, Kossakowski J, Plocker L, Paradowska E. (1958) Congenital Polycystic Dilation Of The Intrahepatic Bile Ducts, Attempt At Classification. [In French.] Sem Hop 34:488–495
[2] Gupta Ak, Gupta A, Bhardwaj Vk, Chansoria M. Caroli's Disease. Indian J Pediatr2006; 73: 233-235
[3] Tiotia R, Sharma M, Narayani V, Singh S, Dewan V, Deswal S Et Al Atypical Presentation Of Caroli's Syndrome: A Case Report. Indian Journal Of Case Reports. 2019:76-8.
[4] Sweeney We, Avner Ed. Polycystic Kidney Disease, Autosomal Recessive. In: Adam Mp, Feldman J, Mirzaa Gm, Pagon Ra, Wallace Se, Bean Ljh, Gripp Kw, Amemiya A, Editors. Genereviews® [Internet]. University Of Washington, Seattle; Seattle (Wa): Jul 19, 2001
[5] Madjov R, Chervenkov P, Madjova V, Balev B. (2005) Caroli's Disease.Report Of 5 Cases And Review Of Literature. Hepatogastroenterology52:606–609.

Abstract: Background: Decompressive craniectomy (DC) is a crucial procedure for managing intracranial hypertension (ICHT) refractory to medical treatment. The increasing utilization of DC has led to a growing demand for subsequent cranioplasty, particularly among patients with traumatic brain injury (TBI), spontaneous subarachnoid haemorrhage, and malignant cerebral infarction. Hemodynamic changes following cranioplasty play a pivotal role in patient outcomes, necessitating comprehensive monitoring to ensure perioperative stability and minimize neurological complications. This prospective observational study aimed to assess hemodynamic parameters in patients undergoing cranioplasty at a tertiary health center. Material & Method: The study....

Keywords: Cranioplasty, Traumatic brain injury, Cerebral blood flow, Transcranial Doppler ultrasound.

[1] Paredes I, Castaño Am, Cepeda S, Alén Jaf, Salvador E, Millán Jm, Et Al. The Effect Of Cranioplasty On Cerebral Hemodynamics As Measured By Perfusion Computed Tomography And Doppler Ultrasonography. J Neurotrauma. 2016;33(17):1586–97.
[2] Honeybul S, Ho Km. Decompressive Craniectomy For Severe Traumatic Brain Injury: The Relationship Between Surgical Complications And The Prediction Of An Unfavourable Outcome. Injury. 2014;45(9):1332–9.
[3] Alahmadi H, Vachhrajani S, Cusimano Md. The Natural History Of Brain Contusion: An Analysis Of Radiological And Clinical Progression. J Neurosurg. 2010;112(5):1139–45.
[4] Honda M, Ichibayashi R, Yokomuro H, Yoshihara K, Masuda H, Haga D, Et Al. Early Cerebral Circulation Disturbance In Patients Suffering From Severe Traumatic Brain Injury (Tbi): A Xenon Ct And Perfusion Ct Study. Neurol Med Chir (Tokyo). 2016;56(8):501–9.
[5] Stocker Ra. Intensive Care In Traumatic Brain Injury Including Multi-Modal Monitoring And Neuroprotection. Med Sci (Basel, Switzerland). 2019;7(3):6–9..

Abstract: Introduction-Cerebral venous thrombosis (CVT) is a rare cerebrovascular disease which occurs due to the occlusion of dural Venous sinus or cerebral veins. CVT has an incidence rate of 1-12 cases per million and constitutes 0.5-3% of all types of cerebrovascular diseases. . Mortality rate of severe CVT can be as high as 34%. Materials and methods-It is a Retrospective study based on review from hospital database of Cortical venous thrombosis patients admitted at our hospital (Travancore Medical college) from October 2019 to September 2023.The aim of the study....

Keywords: CVT, clinical features, Risk factors

[1] Shakywar M, Agarwal A, Srivastava Mp, Bhatia R, Singh Mb, Rajan R, Gupta A, Pandit Ak, Garg A, Sharma J, Gupta A. Predictors Of Seizures And Associated Functional Outcome In A Cerebral Venous Thrombosis Cohort: An Ambispective Cohort Study. Annals Of Indian Academy Of Neurology. 2022 Nov 1;25(6):1056-61.
[2] Duman T, Uluduz D, Midi I, Bektas H, Kablan Y, Goksel Bk, Milanlioglu A, Orken Dn, Aluclu U, Colakoglu S, Tüfekci A. A Multicenter Study Of 1144 Patients With Cerebral Venous Thrombosis: The Venost Study. Journal Of Stroke And Cerebrovascular Diseases. 2017 Aug 1;26(8):1848-57.
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[4] Narayan D, Kaul S, Ravishankar K, Suryaprabha T, Bandaru Vs, Mridula Kr, Jabeen Sa, Alladi S, Meena Ak, Borgohain R. Risk Factors, Clinical Profile, And Long-Term Outcome Of 428 Patients Of Cerebral Sinus Venous Thrombosis: Insights From Nizam′ S Institute Venous Stroke Registry, Hyderabad (India). Neurology India. 2012 Mar 1;60(2):154-9.

Abstract: Spinal teratomas, particularly in the pediatric population, present a diagnostic and therapeutic challenge due to their rarity and diverse clinical presentations. We present a case of a dorsal mature teratoma in a two-year-old child, a rare occurrence not associated with dysraphism. The patient's clinical history revealed delayed walking followed by progressive paraparesis leading to incomplete paraplegia with trophic disorders in both lower limbs. Diagnostic imaging, particularly MRI, played a crucial role in preoperative assessment, while histopathological......

[1] Danison Ap, Ramanathan D, Matin M, Kim K, Panchal Rr. Adult Thoracic Intradural Exophytic Mature Teratoma: About A Case And Review Of The Literature. Asian J Neurosurgery. 2018 ; 13 :1182-5. [ Free Pmc Article ] [ Pubmed ] [ Google Scholar
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Abstract: Adolescence is an important development phase between childhood and adulthood, which is marked by many physical, psychological and social changes. During this period, the individuals are highly energetic, enthusiastic and often show the tendencies to take independent decisions. These behaviors often lead the adolescents to drug abuse. By considering all these facts, it is necessary that concrete steps have to be formulated for eliminating drug abuse among adolescents.....

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Abstract: Mesiodens, a supernumerary tooth located in the midline of the maxilla, is a relatively common developmental anomaly. This case report presents the clinical and radiographic findings of a nine-year-old boy diagnosed with mesiodens. The patient presented with complaints of discomfort and aesthetic concerns in the upper front region of the oral cavity. Clinical examination revealed the presence of an additional tooth between the central incisors. Radiographic evaluation confirmed the presence of a mesiodens, which was identified as a conical supernumerary tooth. Treatment options were.....

Keywords: Supernumerary tooth, mesiodens, extraction

...

Abstract: Résumé Les urgences neurologiques constituent un ensemble de pathologies diverses souvent graves mettant en jeu le pronostic vital et donc nécessitant un diagnostic et un traitement optimal rapide. Dans cet article nous étudierons la fréquence et les caractéristiques des urgences neurologiques au CHU Blida. Patients et méthodes : il s'agit d'une étude prospective au niveau des urgences de neurologie situées au pavillon des urgences du CHU de Blida sur une durée de 05 mois et ayant inclue tous les patients consultant au PU de neurologie quel que soit le motif de consultation......

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[4] Depression After Stroke: A Systematic Review Of Observational Studies. Stroke 36, 1330-1340.
[5] Moulin T, Sablot D, Vidry E, Belahsen F, Berger E, Lemounaud P Et Al. Impact Of Emergency Room Neurologists On Patient Management And Outcome. Eur Neurol 2003 ; 50 : 207-214

Abstract: L'artérite ou la maladie de Takayasu (MT) est une panartérite inflammatoire primitive des vaisseaux de gros calibres qui touche principalement l'aorte et ses principales branches de division. C'est une maladie rare son incidence est estimée à 1,11 /million/ an (1), elle associe des signes généraux inflammatoires non spécifiques à des manifestations ischémiques polymorphes périphériques....

[1] Rutter M, Bowley J, Lanyon Pc, Grainge Mj, Pearce Fa. A Systematic Review And Meta-Analysis Of The Incidence Rate Of Takayasu Arteritis. Rheumatology 2021;60:4982–90.
[2] Shimizu K, Sano K. Pulseless Disease. J Neuropathol Clin Neurol 1951;1: 37–47.
[3] Numano F. The Story Of Takayasu Arteritis. Rheumatology 2002;41: 103–6.
[4] Guédon Af, Bourgade R, Toquet C, Espitia O, Fain O, Mekinian A. Maladie De Takayasu. Emc - Angéiologie 2023;27(1):1-9 [Article 19-1520].
[5] Seko Y, Minota S, Kawasaki A, Shinkai Y, Maeda K, Yagita H, Et Al. Perforin-Secreting Killer Cell Infiltration And Expression Of A 65-Kd Heatshock Protein In Aortic Tissue Of Patients With Takayasu's Arteritis. J Clin Invest 1994;93:750–8

Abstract: Background: The lower limbs pose challenges for reconstruction in cases of complex injuries due to less distensible skin and scant subcutaneous tissue. Satisfactory muscular flaps are limited to the proximal two-thirds of the leg, while graft use is constrained. The sural flap, with its diverse sources of nourishment, provides a viable alternative, particularly for treating complex wounds in the distal region of the legs and feet without microsurgery. This study aims to provide a theoretical review and report the experience of the plastic surgery department at Hospital de Base.....

Keywords: Surgery, Plastic; Surgical Flaps; Lower Extremity; Plastic Surgery Procedures; Sural Nerve

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