iosr-JDMS   Volume-23 ~ Issue-8 ~ August 2024

Abstract: Background: Aloe is a succulent plant known for its diverse medicinal properties, traditionally used in wound healing, anti-inflammatory, and skin care treatments. The bioactive compounds present in both the gel and skin of Aloe vera, including polyphenols, are believed to contribute to its therapeutic effects. Despite its widespread use, there is a need for scientific validation of its potential antithrombotic and antioxidant activities, which could support the development of new functional biomaterials for medical applications. Materials and Methods: In vitro biological activities of Aloe vera gel and skin extracts were evaluated. The total polyphenol content of Aloe vera skin was measured. Antioxidant activities were assessed using DPPH radical scavenging and superoxide......

Key Word: Intrathecal, Bupivacaine, Buprenorphine, Nalbuphine, Postoperative analgesia

[1]. Klein, A. D. And N. Pennys (1988) Aloe Vera. J . Am. Acad. Dermatol. 18: 714-720.
[2]. Hu, Y., J. Xu And Q. Hu (2003) Evaluation Of Antioxidant Potential Of Aloe Vera (Aloe Barbadensis Miller) Extracts. J. Agric. Food Chem. 51: 7788-7791.
[3]. Chitha, P., G. B. Sajithlal And G. Chandrakasan (1998) Influence Of Aloe Vera On Collagen Characteristics In Healing Dermal Wounds In Rats. Mol. Cell Biochem. 181: 71-76.
[4]. Rhim, J. Y., Y. S. Moon, S. H. Jung, K. Y. Lee, S. Y. Lyu, C. S. Shim And W. B. Park (2002) Antimicrobial Activities Of Combined Extract Of Aloe Vera With Propolis Against Oral Pathogens. J. Korean Soc. Food Sci. Nutr. 31: 899-904.
[5]. Shin, Y. (1997) Studies On The Chromones And Anthraquinones In Aloe Barbadensis. Ph.D. Thesis. Seoul National University, Seoul, Korea.

Abstract: Background: internuclear ophthalmoplegia (ino) is a sign of exquisite localizing value, often due to either infarction or multiple sclerosis. This study considers a case series of 10 inpatients whom i personally examined during a one year period. In this series ,the causes of ino was infarction in 7 patients(70%) ,multiple sclerosis in 1 patient (10%),vasculitis in 1(10%) and unknown cause in 1 patient (10%).ino was unilateral in 70% stroke patients,10% vasculitis.....

[1] Virgo Jd, Plant Gt, Internuclear Ophthalmoplegia Pract Neurol.2017 April17:149-153.
[2] Kochar Ps, Kumar Y,, Sharma P, Kumar V .Isolated Medial Longitudinal Fasciculus Syndrome :Review Of Imaging,Anatoy Pathophysiology And Differential Diagnosis
[3] Abel M P, Murphy M T, Enzenauer Rj , Enzenauer R W . Ino : An Unusual Presentation Of Neuropsychiatric L Upus Erythematosus..
[4] Cogan D , Wray Sg,,Ino As An Early Sign Of Brainstem Tumors.Neurology
[5] Frohman T C , Galetta S ,Fox R ,Solomon D ,Straumann D ,Zee D .The Medial Longitudinal Fasciculus In Ocular Motor Physiology..

Abstract: Resume Introduction : Les résultats actuels de cette étude ne soutiennent pas de façon générale la situation épidémiologique des maladies de la prostate dans notre ville de Lubumbashi mais ils révèlent juste la réalité du problème pour l'hôpital général de référence Sendwe où cette étude a été menée. Matériels et Méthodes : Il s'agit d'une étude descriptive transversale à visée analytique qui avait pour objectifs de déterminer......

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Abstract: Anxiety rates are on the rise and affect individuals of all socio-cultural strata, becoming a serious mental health problem. Anxiety is an innate personality trait that allows us to react to situations of imminent danger. It can also manifest itself as an emotional state in situations of joy or sadness, depending on individual perception. This article aims to conduct a literature review on anxiety in medical students during their rotations, exploring both its manifestation.....

Keywords: Anxiety, Medicine, Clinical rotations

[1] American Psychiatric Association (2013) Diagnostic And Statistical Manual Of Mental Disorders. Fifth (Dsm-5) Edition Arlington: American Psychiatric Association.
[2] Almojali, A. I., Almalki, S. A., Alothman, A. S., Masuadi, E. M., & Alaqeel, M. K. (2017). The Prevalence And Association Of Stress With Sleep Quality Among Medical Students. J Epidemiol Glob Health, 7(3), 169-174.
Https://Doi.Org/10.1016/J.Jegh.2017.04.005 [ Links ]
[3] Alcanda Blanca (2022) Cómo Podemos Aprender A Manejar Nuestra Ansiedad? Psicólogos Online. 2008;23: 157-66. [Internet]. 2020 [Consultado 16-Nov-2021]. Disponible En:
[4] Análisis De La Ansiedad En Los Primeros Encuentros Clínicos: Experiencias Utilizando La Simulación Clínica En Estudiantes De Pregrado Nancy De Los Ángeles Segura Azuara, Irma
[5] Azuri J, Ackshota N, Vinker S. (2010) Reassuring The Medical Students' Disease- Health Related Anxiety Among Medical Students. Med Teach. 2010;32:E270-275. [ Links ].

Abstract: Aim :-The aim of the present study was to determine the prevalence of Temporomandibulardisorders (TMD) among students of RCDS & RC Bhopal (M.P.) Material&Methods:-Data wascollected through a specifically designedquestionnaire and then the collected data was analysed using SPSS software Results:-The results of the study concluded that the overall prevalence of both TMJ sign and symptoms in the student population was 12.2% while the remaining 87.8% Students were asymptomatic.....

[1] Sari S, Sonmez H. Investigation Of The Relationship Between Oral Parafunctions And Temporomandibular Joint Dysfunction In Turkish Children With Mixed And Permanent Dentition. J Oral Rehabil. 2002;29(1):108–112.
[2] Schmitter M, Rammelsberg P, Hassel A. The Prevalence Of Signs And Symptoms Of Temporomandibular Disorders In Very Old Subjects. J Oral Rehabil. 2005;32(7):467
[3] Nilner M, Lassing Sa. Prevalence Of Functional Disturbances And Diseases Of The Stomatognathic System In 7-14 Year Olds. Swed Dent J. 1981;5(5-6):173–187.
[4] Nassif Nj, Hilsen Kl. Screening For Temporomandibular Disorders: History And Clinical Examination. American Dental Association. J Prosthodont. 1992;1(1):42–46
[5] 5.List T, Jensen Rh: Temporomandibular Disorders: Old Ideas And New Concepts . Cephalalgia. 2017, 37:692- 704. 10.1177/0333102416686302.

Abstract: Background In India, COVID-19 infection, saw 3 waves with variation in clinical presentation and outcome in each wave. When the second wave (2021) was declining there was an unusual surge in COVID-19 positive cases, which led to global concern about the changes in virus characteristics. Global vaccine development was accelerated in response to the COVID-19 pandemic......

Key Word: Covid -19, Inflammatory Markers, Immunization

[1] Martinelli Aw, Ingle T, Newman J, Nadeem I, Jackson K, Lane Nd, Et Al. Covid-19 And Pneumothorax:A Multicentre Retrospective Case Series. Eur Respir J. 2020;56:2002697. [Pmc Free Article] [Pubmed] [Google Scholar]
[2] Wenham C, Smith J, Morgan R. Gender And Covid-19 Working Group. Covid-19:The Gendered Impacts Of The Outbreak. Lancet. 2020;395:846–8. [Pmc Free Article] [Pubmed] [Google Scholar]
[3] Rozenberg S, Vandromme J, Martin C. Are We Equal In Adversity? Does Covid-19 Affect Women And Men Differently? Maturitas. 2020;138:62–8. [Pmc Free Article] [Pubmed] [Google Scholar]
[4] Vahidy Fs, Pan Ap, Ahnstedt H, Munshi Y, Choi Ha, Tiruneh Y, Et Al. Sex Differences In Susceptibility, Severity, And Outcomes Of Coronavirus Disease 2019: Cross-Sectional Analysis From A Diverse Us Metropolitan Area. Plos One. 2021;1:E0245556. [Pmc Free Article] [Pubmed] [Google Scholar]
[5] Jin J-M, Bai P, He W, Wu F, Liu X-F, Han D-M, Et Al. Gender Differences In Patients With Covid-19:Focus On Severity And Mortality. Front Public Health. 2020;8:152. [Pmc Free Article] [Pubmed] [Google Scholar].

Abstract: Edentulism is acknowledged as a physical impairment that greatly impairs diet, communication, self-esteem, and perceived beauty. Traditionally, patients who have lost all of their teeth have commonly been treated with complete dentures. However, these patients often face challenges such as reduced ability to keep the dentures in place, lack of stability, and difficulty in chewing due to ongoing loss of bone in the upper jaw. These issues have a negative impact on their overall oral health and quality of life [1]. Alternatively, opting for implant-supported overdentures......

[1] Hsu Yj, Lin Jr, Hsu Jf. Patient Satisfaction, Clinical Outcomes And Oral Health-Related Quality Of Life After Treatment With Traditional And Modified Protocols For Complete Dentures. J Dent Sci. 2021;16:236–40.
[2] Borges Ga, Barbin T, Dini C, Et Al. Patient-Reported Outcome Measures And Clinical Assessment Of Implant-Supported Overdentures And Fixed Prostheses In Mandibular Edentulous Patients: A Systematic Review And Meta-Analysis. J Prosthet Dent. 2020;S0022–391:30694–6.
[3] Leão Rs, Moraes Sld, Vasconcelos Bce, Lemos Caa, Pellizzer Ep. Splinted And Unsplinted Overdenture Attachment Systems: A Systematic Review And Meta-Analysis. J Oral Rehabil. 2018;45:647–56.
[4] Roccuzzo M, Bonino F, Gaudioso L, Zwahlen M, Meijer Hj. What Is The Optimal Number Of Implants For Removable Reconstructions? A Systematic Review On Implant-Supported Overdentures. Clin Oral Implants Res. 2012;23:229–37.
[5] Di Francesco F, De Marco G, Gironi Carnevale Ua, Lanza M, Lanza A. The Number Of Implants Required To Support A Maxillary Overdenture: A Systematic Review And Meta-Analysis. J Prosthodont Res. 2019;63:15–24.

Abstract: Nicolau Syndrome, also known as skin reaction embolism, is a rare but serious complication associated with the improper conversion of calcium hydroxide during endodontic treatment. This inflammation can cause serious side effects such as blood clots, tissue damage, and skin necrosis once the substance enters the bloodstream. Despite its seriousness, this condition rarely occurs during root canal treatment. Calcium hydroxide has been a mainstay of root canal treatment for many years, but its adverse effects on nearby vital structures pose significant......

Keywords: Nicolau syndrome, Livedoid dermatitis, Embolia Cutis Medicamentosa, Drug hypersensitivity, Dermatitis, Calcium hydroxide, Diclofenac, Complication, Tissue damage, Vascular thrombosis

[1] Marangi Gf, Gigliofiorito P, Toto V, Langella M, Pallara T, Persichetti P. Three Cases Of Embolia Cutis Medicamentosa (Nicolau's Syndrome). J Dermatol. 2010; 37:488-492.
[2] Corazza M, Capozzi O, Virgilit A. Five Cases Of Livedo-Like Dermatitis (Nicolau's Syndrome) Due To Bismuth Salts And Various Other Non-Steroidal Anti-Inflammatory Drugs. J Eur Acad Dermatol Venereol. 2001; 15:585-588.
[3] Nicolau S. Dermite Livédoïde Et Gangréneuse De La Fesse, Consécutive Aux Injections Intra-Musculaires, Dans La Syphilis: À Propos D'un Cas D'embolie Artérielle Bismuthique. Ann Mal Vener. 1925; 20:321-339.
[4] Saputo V, Bruni G. Nicolau Syndrome Caused By Penicillin Preparations: Review Of The Literature In Search For Potential Risk Factors. Pediatr Med Chir. 1998; 20:105-123.
[5] Ozcan A, Senol M, Aydin En, Aki T. Embolia Cutis Medicamentosa (Nicolau Syndrome): Two Cases Due To Different Drugs In Distinct Age Groups. Clin Drug Investig. 2005; 25:481-483.

Abstract: Background: This study was conducted to evaluate and compare the fracture resistance of monolithic lithium disilicate glass-ceramic onlays with full coverage metal crowns while restoring posterior teeth with extensive carious lesion involving both the marginal ridges. Materials and Methods: Sixteen molars mounted in acrylic blocks were randomly allocated to two groups(n=8). Group I received bonded partial restoration made from lithium disilicate pressed ceramic involving MOD onlay preparation.....

Keywords: Fracture resistance; bonded ceramic restoration; onlays; full coverage crowns; wide cavities

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Abstract: Background: distal end radius fractures constitute 20% of fractures managed in emergency departments.the objective of our study is to compare functional and radiological outcome of pop cast compared percutaneous k wire fixation in distal radius fractures. Materials and methods: this prospective study included 50 patients with distal radius fractures.25 patients were treated with pop cast and 25 patients were treated with percutaneous k wire fixation. The functional outcome of wrist was assessed using......

Keywords: distal radius fractures,popcast,percutaneous k wire fixation,range of motion,increased stability

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Abstract: Background: acl reconstruction has been described using a variety of approaches till date ranging from open to arthroscopic.the most often used graft in acl reconstruction was bone-patellar tendon-bone graft. However,issues with the knees extensor function loss of mobility,patellar instability and continued presence of anterior knee function have forced surgeons to consider alternate graft materials for use in acl reconstruction. The objective of our study is to compare functional outcome of arthroscopic acl reconstruction with autologous hamstrings tendon graft versus autologous quadriceps tendon graft. Materials and methods:.....

Keywords: anterior cruciate ligament reconstruction,autologous quadriceps tendon autograft,autologous hamstring tendon autograft

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Abstract: Background: Primary insomnia is defined as sleep difficulties that affect day-time functioning. Its prevalence rates for the general adult population are approximately 1%-10% and elderly population is up to 25%. Deep Relaxation Technique (DRT) is guided relaxation technique in yogic practices. There are no scientific evidences available for DRT on primary insomnia. This is to find out the effect of Deep Relaxation Technique on Sleep Quality in Primary Insomnia. Materials and Methods: This is a randomized controlled trial with sample size of 80. Subjects will be divided into two group namely, intervention.......

Keywords: Sleep, Insomnia, Relaxation technique, Yoga, Adjuvant therapy, Quality of life

[1] Zhao Fy, Spencer Sj, Kennedy Ga, Zheng Z, Conduit R, Zhang Wj, Et Al. Acupuncture For Primary Insomnia: Effectiveness, Safety, Mechanism And Recommendations For Clinical Practice. Sleep Medicine Reviews. 2023; 11:101892.
[2] Maire M, Linder S, Dvořák C, Merlo C, Essig S, Tal K, Del Giovane C, Et Al. Prevalence And Management Of Chronic Insomnia In Swiss Primary Care: Cross‐Sectional Data From The "Sentinella" Practice‐Based Research Network. Journal Of Sleep Research. 2020 ;29(5):13121.
[3] Van Someren Ej. Brain Mechanisms Of Insomnia: New Perspectives On Causes And Consequences. Physiological Reviews. 2021;101(3):995-1046.
[4] Khachatryan Sg. Insomnia Burden And Future Perspectives. Sleep Medicine Clinics. 2021;16(3):513-21.
[5] Hrehova L, Mezian K. Non‐Pharmacologic Treatment Of Insomnia In Primary Care Settings. International Journal Of Clinical Practice. 2021 Jun;75(6):14084

Abstract: Background and objective:- Obstructive sleep Apnea is a serious condition that can have significant health consequences. The recurrent episodes of complete or partial blockage of the upper airway during sleep, which may cause pauses in breathing and reduce the amount of oxygen that reaches the brain and the rest of the body2. The present study will attempt to identify the various barriers that are involve in the treatment of obstructive sleep Apnea in geriatric population through questionnaire. Method:-In this study, 325(2016 male and 108 female) edentulous subjects were taken between the ages of 45-60 years. All selected subjects were agreed to take the......

[1] Okşayan R, Sökücü O, Uyar M, Topçuoğlu T: Effects Of Edentulism In Obstructive Sleep Apnea Syndrome. Nigerian Journal Of Clinical Practice. 2015, 1:5. 10.4103/1119-3077.154203
[2] Motamedi Kk, Mcclary Ac, Amedee Rg: Obstructive Sleep Apnea: A Growing Problem. Ochsner Journal. 2009, 21:149-53.
[3] Bernhardt L, Squire I, Robertson N: Barriers And Enablers To The Diagnosis And Treatment Of Obstructive Sleep Apnoea In Chronic Heart Failure From Patients' And Clinicians' Perspectives. European Journal Of Cardiovascular Nursing. 2022, 21:060-011. 10.1093/Eurjcn/Zvac060.011
[4] Colt Hg, Haas H, Rich Gb: Hypoxemia Vs Sleep Fragmentation As Cause Of Excessive Daytime Sleepiness In Obstructive Sleep Apnea. Chest. 19911, 100:1542-8. 10.1378/Chest.100.6.1542
[5] Sanders Ae, Akinkugbe Aa, Slade Gd, Essick Gk: Tooth Loss And Obstructive Sleep Apnea Signs And Symptoms In The Us Population. Sleep And Breathing. 2016, 20:1095-102. 10.1007/S11325-015-1310-Z