iosr-JDMS   Volume-23 ~ Issue-8 ~ August 2024

Abstract: Background: Prevalence of type 2 diabetes mellitus (T2DM) has increased worldwide to a frightening level in both developed and developing countries over the last decades. Higher prevalence of thyroid dysfunction among diabetic patients has been recognized than that in general population. There is a complex inter-relation between diabetes and thyroid dysfunction which involves biochemical, genetic, hormonal and pathophysiological mechanisms. Objective: Aim of the study was to.....

Keywords: Type 2 diabetes mellitus, Thyroid dysfunction, Thyroid stimulating hormone, plasma glucose

[1]. International Diabetic Federation; Idf Diabetes Atlas: 2019 [Accessed 17 May 2021].
[2]. Vinu V, Chitnis P, Gupta Vk. Evaluation Of Thyroid Dysfunction Among Type 2 Diabetic Patients. International Journal Of Pharmacy And Biological Sciences. 2012;2(4):150-55.
[3]. Perros P, Mccrimmon Rj, Shaw G, Frier Bm. Frequency Of Thyroid Dysfunction In Diabetic Patients: Value Of Annual Screening. Diabetic Medicine. 1995;12(7):622-7.
[4]. Palma Cc, Pavesi M, Nogueira Vg, Clemente El, Vasconcellos Md, Pereira Lc Et Al. Prevalence Of Thyroid Dysfunction In Patients With Diabetes Mellitus. Diabetology & Metabolic Syndrome. 2013; 5:1-5.
[5]. Umpierrez Ge, Latif Ka, Murphy Mb, Lambeth Hc, Stentz F, Bush A Et Al. Thyroid Dysfunction In Patients With Type 1 Diabetes: A Longitudinal Study. Diabetes Care. 2003;26(4):1181-5.

Abstract: Background: Age estimation plays a crucial role in forensic identification and is also valuable in archaeological and anthropological research. Various methods exist for age estimation, among which dental radiography has gained prominence due to its reliability and non-invasive nature. The pulp chamber crown root trunk height ratio (PCTHR) is an emerging method for age estimation using Orthopantomography (OPG). Objective: This study aims to establish a relationship between chronological age and PCTHR and to derive a regression model for accurate......

Keywords: Age estimation, pulp chamber height, Orthopantomography, dental radiography, regression analysis.

[1] Sakuma H, Kondo T, Morita T, Et Al. Adult Forensic Age Estimation Using Mandibular First Molar Radiographs: A Novel Technique. J Forensic Dent Sci. 2013;5(1):56-59.
[2] Agrawal A, Kumar A, Kumar P, Singh A. Age Estimation By Antegonial Angle, Depth Measurement And Tooth Coronal Index By Digital Panoramic Radiography: A Retrospective Study. International Journal Of Health Sciences. 2018;6(S3):998-1005.
[3] Khattab Naf, Marzouk Hm, Abdel Wahab Tm. Application Of Tooth Coronal Index For Age Estimation Among Adult Egyptians. Journal Of Forensic Science. 2019;64(4):988-993.
[4] Zulkarnain, Wuryadi D, Amaliya S, Et Al. Radiographic Age Estimation With Tooth Coronal Index (Tci) Benindra Method At Sultan Agung Dental Hospital Semarang. Denta Jurnal Kedokteran Gigi. 2023;17(1):30-36.
[5] Singh G, Kaur J, Sekhon Ps, Et Al. Digitized Radiographic Analysis Of Coronal Pulp For Age Estimation In Adults Using Tooth Coronal Index Method – A Pilot Study. Journal Of Forensic Dental Sciences. 2021;13(1):38-43..

Abstract: Mandible is one of those facial bones which is more prone to fractures during trauma. The treatment of such fractures is necessary to prevent functional complications like malocclusion. As history has witnessed a leap in the treatment options for mandibular fractures, here we report a case of left parasymphysis and right Angle of mandible fracture treated with a straight 6 holed with gap titanium mini-plate at the right angle and a 3D titanium mini-plate at the parasymphysis, as these are best available options in recent times. The patient presented with swelling on the right lower......

Keywords: mandibular fracture, maxillo-mandibular fixation, 3d plates, mini-plate fixation, history of mandibular fracture treatment

....

Abstract: Background: Shift work has become a prevalent work schedule globally, known to disrupt the circadian rhythm and detrimentally impact worker health. The inflammasome NLRP3, a crucial component in disease development, responds to various stimuli, including pathogen- and damage-associated molecular patterns (PAMPs and DAMPs). Calibration of NLRP3 levels may serve as an early biomarker for health risk prediction .
Method:.......

Keywords: shift work, night work, inflammatory response, NLRP3 inflammasome, autophagy, oxidative stress

....

Abstract: Background: Colorectal cancer is one of the most common malignancies and the fourth leading cause of cancer mortality in the world. HALP score is a comprehensive index that reflects components of the nutritional and immune status of patients, which had been shown to have a prognostic role in gastrointestinal cancers, including gastric cancer, esophageal cancer, colorectal cancer, and genitourinary cancers, including bladder cancer, and renal cell carcinoma. It is calculated according to the following formula: [hemoglobin (g/L) × albumin (g/L) × lymphocytes (/L)] / platelets......

Keyword: Metastatic colorectal Cancer, HALP score, CAPEOX, FOLFOX, Palliative chemotherapy, Progression free survival, Overall Response Rate

[1]. National Comprehensive Cancer Network. Colon Cancer Version 4.2024. Http://Www.Nccn.Org/Professionals/Physician_Gls/Pdf/Colon.Pdf
[2]. Christian Mark Farag, Ryan Antar, Sinan Akosman, Matthew Ng, And Michael J. Whalen. What Is Hemoglobin, Albumin, Lymphocyte, Platelet (Halp) Score? A Comprehensive Literature Review Of Halp's Prognostic Ability In Different Cancer Types. Oncotarget. 2023; 14: 153–172.
[3]. Xu H, Zheng X, Ai J, Yang L. Hemoglobin, Albumin, Lymphocyte, And Platelet (Halp) Score And Cancer Prognosis: A Systematic Review And Meta-Analysis Of 13,110 Patients. Int Immunopharmacol. 2023; 114:109496.
[4]. Gay Lj, Felding-Habermann B. Contribution Of Platelets To Tumour Metastasis. Nat Rev Cancer. 2011; 11:123–34.
[5]. Pinedo Hm, Verheul Hm, D'amato Rj, Folkman J. Involvement Of Platelets In Tumour Angiogenesis? Lancet. 1998; 352:1775–77. 10.1016/S0140-6736(98)05095-8.

Abstract: techniques, expanding the possibilities for effective surgical outcomes. This review explores the latest trends and innovations in the field, including breakthroughs in 3D printing, tailored flap designs, and refined microsurgical techniques. These innovations are examined for their potential to enhance tissue healing, precision, and customized outcomes.This review consolidates various local and regional flaps for the reconstruction of oral and maxillofacial defects, detailing their indications, contraindications, and harvesting techniques. Emerging research.......

Keywords: Oral Reconstruction, Flap Techniques, Free Tissue Transfer, Microsurgery, 3D Imaging, Donor Site Morbidity Functional & Aesthetic Outcomes, Head and neck cancer

[1]. Wong C & Wei F. Microsurgical free flap in head and neck reconstruction. Head. Neck. 2010; 32, 1236– 1245.
[2]. Liu WW, Yang A & Ou YD. The harvesting and insetting of a chimeric anterolateral thigh flap to reconstruct through and through cheek defects. Int. J. Oral. Maxillofac. Surg. 2011; 40, 1421–1423.
[3]. Liu WW, Zhang CY, Li JY, Zhang MF & Guo ZM. A novel classification system for the evaluation and reconstruction of oral defects following oncological surgery. Oncol. Lett. 2017; 14, 7049–7054.
[4]. Wehage IC & Fansa H. Complex reconstructions in head and neck cancer surgery: decision making. Head. Neck Oncol. 2011; 3, 14.
[5]. Huang W, Chen H, Wei F, Cheng M & Schnur DP. Chimeric flap in clinical use. Clin. Plast. Surg. 2003; 30, 457–467.

Abstract: Temporomandibular joint disorders (TMDs) are becoming more common among children and adolescents, presenting distinct diagnostic and treatment challenges. Symptoms such as pain, limited mouth opening, and joint noises differ by age, requiring a nuanced diagnostic approach. Accurate diagnosis demands a detailed clinical examination, comprehensive patient history, and advanced imaging techniques such as Magnetic Resonance Imaging (MRI) and Cone Beam Computed Tomography (CBCT). Initial treatment typically involves conservative measures like occlusal splints and physical therapy, while more severe cases may necessitate orthodontic or, in rare....

Keywords: Temporomandibular Disorders, Children, Adolescents, Diagnostic criteria, Myalgia

....

Abstract: Complicated crown fractures most commonly affect maxillary anterior teeth, which raise significant aesthetic and psychological issues. The location and extent of these fracture significantly influence the available treatment options and their outcome. Restoring oblique crown fractures that extend below the gingival margin and the alveolar bone, can be challenging. In such cases exposing the fracture line into oral cavity would be desirable which can be done by gingival crown lengthening, orthodontic extrusion or surgical extrusion. With orthodontic extrusion there would be no loss.....

Key Word: Complicated crown fracture, Cross bite, Orthodontic extrusion, MTA, Porcelain laminate veneers

[1] Enshaei Z, Ghasemi M. Multidisciplinary Management Of Complicated Crown-Root Fracture: A Case Report. J Dent (Tehran). 2018;15(3):193-6.
[2] Artieda-Estanga A, Castelo-Baz P, Bello-Castro A, Ramos-Barbosa I, Martin-Biedma B, Blanco-Carrion J. Management Of A Crown-Root Fracture: A Novel Technique With Interdisciplinary Approach. J Clin Exp Dent. 2018;10(6): E620-3.
[3] Wang Jing, Huo Na, Cai Chuan, Xu Lulu. Orthodontic Extrusion With Crown Restoration In The Management Of Anterior Teeth Crown-Root Fracture. 2023: A Case Report. 2(1).
[4] Brown, G., Welbury, R. Root Extrusion, A Practical Solution In Complicated Crown-Root Incisor Fractures. Br Dent J 189, 477–8.
[5] Azzaldeen, Abdulgani And Abu-Hussein Muhamad. Restoration Of Esthetics Using Ceramics Laminate Veneer. Clinical Review: A Case Report. 2015

Abstract: Aim: This systematic review aimed to compare different attachment systems used in implant-supported overdentures by assessing outcomes such as prosthodontic maintenance and complications, peri-implant tissue changes, retention, and patient satisfaction for the optimal selection of an attachment system. Settings and Design: This review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Materials and Methods: A comprehensive.....

Key Word: "O" ring attachment, ball and bar, implant supported overdenture, locator attachment, overdenture attachments

...

Abstract: Background and study aims : Our work aimed to describe the epidemiological, clinical, and para-clinical aspects as well as the therapeutic modalities of the portal cavernoma cholangiopathy (PCC). Patients and methods: This was a retrospective single-center descriptive study over 7 years (2016-2023). We included all patients presenting Portal cavernoma cholangiopathy......

Keywords: Portal cavernoma , Portal Cholangiopathy ,Cholangio-pancreatic-MRI , biliary Stent

...

Abstract: The placenta forms a functional unit between the mother and the fetus, and any pathological event concerning the mother or the fetus will influence the normal function of the placenta, resulting in morphological changes. There is a paucity of literature on the histopathology of the placenta in sickle cell anaemia during pregnancy. Hence, the present study was undertaken to analyze the spectrum of histopathological changes in the placenta in sickle cell anaemia during pregnancy. This prospective study on placenta from mothers with prior consent who delivered at a tertiary care centre for a period of 2 years was undertaken in the present study. 112 mothers willing to undergo the study were selected from the admission list and divided into two groups: (1) sickle cell anaemia group (n=56.....

[1] Langston C, Kaplan C, Macpherson T, Manci E, Peevy K, Clark B. Practice Guideline For Examination Of The Placenta. Arch Pathol Lab Med 1997; 121:449-472.
[2] Klebanoff Ma, Shrono Ph, Selby Ju, Trachtenberg Ai, Gaubard Bi. Anemia And Spontaneous Preterm Birth. Am J Obstet Gynaecol 1991; 164: 59-63.
[3] Liebermani E, Ryan Kj, Monson Rr. Association Of Maternal Hematocrit With Premature Labour. Am J Obstet. Gynaecol. 1988; 159:107.
[4] Collins P. Embryology And Development. In: Bannister Lh. Berry Mm, Collins P, Dyson M, Dussek Je, Ferguson Mwj Eds. Grays Anatomy. London: Churchill Livingstone; 1995. 166-173.
[5] Fox H. Pathology Of Placenta. 2nd Edn Philadelphia: W.B. Saunders Co.Ltd; 1997