iosr-JDMS   Volume-15 ~ Issue-11 ~ November-2016

Abstract: Objective: to evaluate the maternal profile and neonatal profile and immediate neonatal morbidity and mortality till discharge. Methods: the study was a hospital based prospective study conducted in the dept. of paediatrics, Chittaranjan seva sadan college of obstetrics, gynaecology and child health, during the period of 2012-20143.1871 cases of LBW babies were included out of of the 3335 admission in the said department during the period from2013 to 2014............

Keywords: Antenatal Profile, Preterm Labour, Lbw, Vlbw.

[1]. Ministry of statistics and program implementation chindren in India 2012- A statistical appraisal. P : 10.
[2]. Sachdev HPS, low birth weight in south asia in : malnutrition in south Asia, a regional profile Ed Gillaspie S. United Nations children fund, regional office of south asia. Publication No. 5 1997: P : 43-75.
[3]. K. Kapoor. G. Kumar, C.S. Panda, K. Anand incidence of law birth weight of rural ballabgarh, Haryana India pediatric 2001 : 38 ; 271-275.
[4]. Gopalan C. nutrition research in south East Asia, the emerging agenda of the future. Regional office for South-East Asia, world health organization New Delhi 1994 : P: 13-31 .
[5]. Singh Uma, Singh Nisha, Seth Sikha, J. Obstel Gynacal Indian Vol. 57 , No.1: Jan, Feb, 2007, P: 48-52.

Abstract: Infections caused by extended spectrum beta-lactamase (ESBL) producing Klebsiella spp. are associated with higher morbidity and mortality with limited treatment options. As there is no centralized national data in India, the prevalence of ESBL producing Klebsiella spp. is obtained from various scattered publications across the country. This varies widely from 10.10% to 87.00%. So it is important to do periodic surveillance at each institutional level to monitor the prevalence ESBL producers and take measures to contain their spread. This retrospective study was undertaken to identify the prevalence of ESBL producing Klebsiella spp. and their susceptibility pattern in a tertiary care hospital. Total of 209 Klebsiella spp. isolates were identified from various clinical specimens............

Keywords: extended spectrum beta lactamase (ESBL), Klebsiella species, and susceptibility pattern

[1]. R Podschun, U Ullmann. Klebsiella spp. as Nosocomial Pathogens: epidemiology taxonomy, typing methods and pathogenicity factors. Clin Microbiol Rev 11(4), 1998, 589-603.
[2]. TP Van Boeckel, S Gandra, A Ashok, Q Caudron, BT Grenfell, SA Levin and R Laxminarayanan. Global antibiotic consumption 2000 to 2010: An Analysis of National pharmaceutical Sales Data. The Lancet Infec Dis, 14, 2014, 742-750.
[3]. PM Hawkey. The growing burden of antimicrobial resistance. J Antimicrob Chemother, 62 Suppl. I, 2008, i1-i9.
[4]. AA Medeiros. Evolution and dissemination of beta-lactamases accelerated by generations of beta-lactam antibiotics. Clin Infect Dis, 24, 1997,S19-45.
[5]. A Kapil. The challenge of antibiotic resistance: Need to contemplate. Indian J Med Res, 121, 2005, 83-91.

Abstract: Introduction: Teaching in medicine should focus on enabling students to acquire knowledge and skill which translates in to best clinical outcomes. Class room based teachings or group discussions don't impart principles of team work, coordination or decision making which is prudent in an emergency situation. Introduction of technology based teaching like simulation is the need of the hour in medical curriculum. Methodology: A total of 21 medical students trained in basic life support underwent an algorithm based class room lecture on shockable rhythm following which they were randomly divided in to 2 groups, 10 students were allocated to Non-simulation and 11 in HPS (Simulation) group.........

Keywords: Human patient Simulation, Medical students

[1]. Frohna AZ, Hamstra SJ, Mullan PB, Gruppen LD. Teaching medical education principles and methods to faculty using an active
learning approach: the University of Michigan Medical Education Scholars Program. Academic medicine: journal of the
Association of American Medical Colleges. 2006; 81(11):975-8.
[2]. Graffam B. Active learning in medical education: strategies for beginning implementation. Medical teacher. 2007; 29(1):38-42.
[3]. Ruesseler M, Weinlich M, Muller MP, Byhahn C, Marzi I, Walcher F. Simulation training improves ability to manage medical
emergencies. Emergency medicine journal: EMJ. 2010; 27(10):734-8.
[4]. Han JE, Trammell AR, Finklea JD, Udoji TN, Dressler DD, Honig EG, et al. Evaluating Simulation-Based ACLS Education on
Patient Outcomes: A Randomized, Controlled Pilot Study. Journal of graduate medical education. 2014; 6(3):501-6.
[5]. King JM, Reising DL. Teaching advanced cardiac life support protocols: the effectiveness of static versus high-fidelity simulation.
Nurse educator. 2011; 36(2):62-5.

Abstract: Objective/Aims: The study sought to analyze Whipple procedure in 65 patients' in-hospital evaluation of morbidity and mortality rate after pancreatoduodenectomy (PD) with adjusted duct-to mucosa pancreaticojejunostomy. Methods: A retrospective study of 65 consecutive patients that underwent (PD) at 'The First Affiliated Hospital of Anhui Medical University teaching Hospital during the period of December 2008 to December 2015 was done. A two-layered duct-to-mucosa pancreaticojejunostomy over an internal transanastomotic stent was performed in all 65 patients..........

Keywords: Pancreatoduodenectomy, duct-to-duct (DTD) Pancreatic fistula, Pancreaticojejunostomy

[1]. Horstmann O, Markus PM, Ghadimi MB, Becker H. Pylorus preservation has no impact on delayed gastric emptying after pancreatic head resection. Pancreas 2004; 28: 69-74 [PMID: 14707733. DOI: 10.1007/s00268-009-0179-z.]
[2]. Tajima Y, Kuroki T, Tsuneoka N, Adachi T, Kosaka T, Okamoto T, Takatsuki M, Eguchi S, Kanematsu T. Anatomy-specific pancreatic stump management to reduce the risk of pancreatic fistula after pancreatic head resection. World J Surg 2009; 33: 2166-2176. [PMID: 19657576. DOI: 10.1007/s00268-009-0179-z.]
[3]. Büchler MW, Friess H, Wagner M, Kulli C, Wagener V, Z'GraggenK. Pancreatic fistula after pancreatic head resection. Br J Surg 2000; 87: 883-889. [PMID: 10931023 DOI: 10.1046/j.1365-2168.2000.01465.x]
[4]. Sato N, Yamaguchi K, Chijiiwa K, Tanaka M. Risk analysis of pancreatic fistula after pancreatic head resection. Arch Surg 1998; 133: 1094-1098 [PMID: 9790207 DOI: 10.1007/s00268-009-0179-z.]
[5]. Hashimoto N, Yasuda C, Ohyanagi H. Pancreatic fistula after pancreatic head resection; incidence, significance and management. Hepatogastroenterology 2003; 50: 1658-1660 [PMID: 14571810 DOI: ]

Abstract: A 37 year old female presented to our Out Patient Department with complaints of visual loss in LE since 4months.Visual acuity in RE 6/6 and LE 6/60 not improving with pin hole. Anterior segment examination in RE was within normal limits LE revealed 0.3 log units RAPD. A routine confrontation test showed field defects inferotemporal field defects in BE. 30-2 HFA visual field test showed bi temporal hemifield defects. Fundus examination with 90 D in RE was normal and LE showed temporal pallor of optic disc. MRI scan revealed pituitary macroadenoma with mass effect over left optic chiasma and left optic nerve. Endocrinological reports revealed raised prolactin hormone levels suggestive of prolactin secreting pituitary tumour.

Keywords: Temporal pallor, Pituitary macroadenoma, Optic chiasma, Prolactinoma ,Cabergoline.

[1]. Ezzat,Shereen; Asa, Sylvia l.;Couldwell, William T.;Barr,Charles E.;Dodge,William E.;Vance,Mary Lee;McCutcheon, Ian
E.(2004)."The prevalence of pituitary adenomas". Cancer.101 (3): 613-9.
[2]. Asa SL.Tumours of the pituitary gland.Rosaij(Ed),.(Atlas of tumor pathology.3rd series Fascicle 22.Washington,DC,1998):Armed
Forces Institute of Pathology, :1-214
[3]. Talkad AV, Kattah JC, Xu MY, et al. Prolactinoma presenting as painful postganglionic Horner syndrome. Neurology. 2004 Apr
27.62(8):1440-1
[4]. Asa SL,Ezzat S.(The pathogenesis of pituitary tumors.Nat Rev Cancer.2002);2 836-849
[5]. Fujimoto N, Saeki N, Miyauchi O, Adachi-Usami E. Criteria for early detection of temporal hemianopia in asymptomatic pituitary
tumor. Eye (Lond) 2002;16:731–8.

Abstract: Background: Urinary tract infection (UTI) is a serious problem in the geriatric age group. The knowledge of the clinico-microbiological profile and the antibiotic sensitivity pattern is essential for effective management of the problem. Aim: To find the epidemiological data, common presenting symptomatology, risk factors associated with UTI ,distribution of uropathogens isolated and their sensitivity pattern. Methodology: An observational prospective study done in a tertiary care teaching hospital in Bhubaneswar, India. Elderly patients aged 60 years and above admitted to the hospital in whom UTI was confirmed with culture positivity were included in the study.......

[1]. Health action(2004), Eldercare,Feb. 2004, Vol-17, No.2.
[2]. Lim VH, Whitehurst T, Usoro E, Ng SM. Management of urinary tract infections in elderly patients: Strategies for
improvement.BMJ Qual improve. Report. 2014;3:doi:10.1136/bmjquality.u203314.w1503
[3]. Tal S, Guller V, Levi S, Bardenstien R, Berger D, Gurevich I et al. Profile and prognosis of febrile elderly patients with bacteremic
urinary tract infection.J Infect. 2005;50:296-305
[4]. Durgesh D Wasnik, P M Tumane. Prevelance and antibacterial susceptibility pattern of urinary tract infection causing Human
pathogenic bacteria.Asian Journal of Biomedical and pharmaceutical Sciences. 2(15); 2012:1-3
[5]. Vaudevan R. Urinary tract infection: An overview of the infection and the associated risk factors. J Microbiol Exp.
2014:1(2):00008 doi:15406/jmen.2014.01.00008

Abstract: Therapies to stabilize clinical manifestations and prolong pregnancies to attain fetal viability in preeclampsia do not exist1. Antiangiogenic factor, Soluble fms-like tyrosine kinase1 (sFlt-1) induces preeclampsia-like phenotype in experimental models2, and circulates at high levels inpreeclampsia. Extracorporeal removal of circulating sFlt-1 by Dextran-sulfate apheresis reduces proteinuria and stabilizes blood pressure without apparent adverse effects on fetus and mother1.Serum, Urine, and fractional excretion of sFlt-1 are much higher among severe preeclamptic women compared to mild pre-eclamptic controls3. Consuming plenty oral fluids and producing urine output more than 2500ml/24hrs, may significantly reduce clinical symptoms, and may help to continue pregnancies to viability, as enhanced sFlt1 renal excretion is possibled..............

Keywords: Oral Hydration therapy; Very preterm Preeclampsia.

[1]. Thadhani R,Kisner T, Hagmann H et al, Pilot study of extracorporeal removal of soluble fms-like tyrosine kinase 1 in preeclampsia;Circulation. 2011 Aug 23; 24(8):940-50
[2]. Camille E. Powe, AB.Richard, J. Levine, et al Preeclampsia, a disease of the maternal endothelium: the role of anti-angiogenic factors and implications for later cardiovascular disease. Circulation. 2011 Jun 21; 123(24): 10.1161 [3]. Buhimschi CS1, Magloire L, Funai E, et al. Fractional excretion of angiogenic factors in women with severe preeclampsia.Obstet Gynecol. 2006 May; 107(5):1103-13 [4]. Samartha Ram H. Sai Samyukta I. Padmapriya A,Preeclampsia and Eclampsia: A consequence of Immunological maladaptation. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS); 2279-0861.Volume 14, Issue 11 Ver. III (Nov. 2015), PP 20-32
[5]. C. R. Leitch, A. D. Cameron, J. J. Walker; The changing pattern of eclampsia over a 60-year period; BJOGA. August 1997 Volume 104, Issue 8 Pages 917–922.

Abstract: Malaria is one of the most common disease which is responsible for a major public health problem in Indian Scenario. The National Vector borne disease control programme of India reported 1.6 million cases and 1100 malaria deaths in the year 2009. But according to many reports this number is grossly under-reported. Symptoms of malaria are generally non-specific and usually consists of fever, malaria, weakness, headache, backpain, nausea, vomiting and other GI symptoms.Also if left untreated it can also lead to several complications like Cerebral Malaria, Hypoglycaemia, Hepatic impairement and renal impairement. This study was designed to assess clinical features and laboratory parameters in hospitalized patients of malaria in Western U.P.

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Abstract: Background : Dyslipiemia is a modifiable risk factor for coronary heart disease. Yoga which aims at harmonizing mind, body and spirit, has been shown to be useful in correcting dyslipidemia. Objectives : To assess the effect of Yoga on lipid profile parameters in mild hypertensive patients (stage 1 of JNC 7 classification ) who are not in any form of medication. Materials And Methods : Fifty mild hypertensives (28 males and 22 females ) with systolic blood pressure (SBP) 140 to 159 mmHg and/or Diastolic blood pressure (DBP) 90 to 99 mmHg in the age group of 25-65 years who came to practise yoga at the Yoga Training and Research Centre) Kwakeithel..............

Keywords: yoga, hypertensive, dyslipidemia , blood pressure, heart rate

[1]. Iyengar BKS. Light on Yoga; Yoga Dipika.New York: Schoken Books;1966.
[2]. Cohen D and Townsend RR. Yoga and hypertension. J Clin Hypertens, 9, 2007, 800-801.
[3]. Bijlani RL, Manjunatha S. Understanding Medical Physiology. 4th ed. Daryaganj (New Delhi): Jaypee publishers; 2011.
[4]. Prasad KVV, Sunita M, Raju PS, Reddy MV, Sahay BK and Murthy KJR. Impact of Pranayama and Yoga on Lipd Profile in
normal healthy volunteers. JEP online, 9(1), 2006, 1-6.
[5]. Mahajan AS, Reddy KS and Sachdeva U. Lipid profile of coronary risk subjects following yogic lifestyle intervention. Indian Heart,
51(1), 1999, 37-40.

Abstract: Kartagener syndrome is a subset of primary ciliary dyskinesia, an autosomal recessive condition characterized by abnormal ciliary structure or function leading to impaired mucociliary clearance. The findings of CT thorax, abdomen and PNS support the clinical diagnosis of the Kartageners Syndrome. We report one of this rare syndrome from a rural Medical college &Hospital of West Bengal..............

[1]. Boat TF, Carson JL. Ciliary dysmorphology and dysfunction: Primary or acquired? N Engl J Med.1990;323:1700–2.
[2]. Afzelius BA. Immotile Cilia syndrome: Past, present and prospects for the future. Thorax. 1998;53:894–7.
[3]. Sturgess JM, Chao J, Wong J, Aspin N, Turner JA. Cilia with defective radial spokes: A cause of human respiratory disease. N
Engl J Med. 1979;300:53–6.
[4]. Sturgess JM, Chao J, Turner JA. Transposition of ciliary microtubules: Another cause of impaired ciliary motility. N Engl J
Med. 1980;303:318–22.
[5]. Rutland J, de Iongh RU. Random ciliary orientation. A cause of respiratory tract disease. N Engl J Med.1990;323:1681–4.

Abstract: The present study was undertaken with the aim to evaluate the histopathological correlation with cervical cytology among patients attending GOPD of Gauhati Medical College, Guwahati. It was a prospective, cross sectional study over a period of 1 year from July 2015 – June 2016. Total number of 280 patients with complaints of vaginal discharge, irregular bleeding, post coital bleeding, pain abdomen were randomly selected. Out of 280 cases 153 that is 55 % had NILM in PAP smear, 25% (70/280) had ECA.............

Keywords: Papanicolau smear , cervical cytology, PAP test, ASCUS

[1]. Parkin DM, Pasini P, Ferlay J. Estimates of the worldwide incidence of 25 major cancers in 1990. Int J Cancer 1999;54:827–41.
[2]. Cervical Cancer http://www.cdc.gov/cancer/cervical/pdf/cervical_facts.pdf
[3]. Annekathryn Goodman HPV testing as a screen for cervical cancer BMJ 2015; 350 doi: (Published 30 June 2015).
[4]. Mehta V, Vasanth V , Balachandran C. Pap smear. Indian J Dermatol Venereol Leprol 2009; 75: 214-6
[5]. Bal S M, Goyal R:Detection of abnormal cytology in PAP smear. Cytojournal 2012 ;29(l).45-47

Abstract: Back ground : Vernal keratoconjunctivitis (VKC) is an allergic disease that typically affects young individuals with male preponderance.[1,2] Prevalence of VKC is seen in the regions with hot, humid climate, and higher load of airborne allergens. Patients with VKC experience significant morbidity, which affects the quality of life;[8] moreover, vision-threatening corneal complication in severe and chronic cases coupled with potential iatrogenic side effects makes VKC a concerning ocular surface disorder. Material&methods:.............

Keywords: Allergic Eye Disease, Papillae, Shield ulcer, Vernal Keratoconjuctivitis.

[1]. Leonardi A, Secchi AG. Vernal keratoconjunctivitis. IntOphthalmolClin. 2003;43:41–58.
[2]. Bonini S, Coassin M, Aronni S, Lambiase A. Vernal keratoconjunctivitis. Eye (Lond) 2004;18:345–51.
[3]. Leonardi A, Busca F, Motterle L, Cavarzeran F, Fregona IA, Plebani M, et al. Case series of 406 vernal keratoconjunctivitis
patients: A demographic and epidemiological study. Acta Ophthalmol Scand.2006;84:406–10.
[4]. Lambiase A, Minchiotti S, Leonardi A, Secchi AG, Rolando M, Calabria G, et al. Prospective, multicenter demographic and
epidemiological study on vernal keratoconjunctivitis: A glimpse of ocular surface in Italian population. Ophthalmic
Epidemiol. 2009;16:38–41. 5. Tabarra KF. Ocular complications of vernal keratoconjunctivitis. Can J Ophthalmol. 1999;34:88–92.
[5]. Ukponmwan CU. Vernal conjunctivitis in Nigerians: 109 consecutive cases. Trop Doct. 2003;33:242–5.

Abstract: Objectives: This study was undertaken to assess the resolution of ST segment at 90 min of thrombolysis in ST segment elevation myocardial infarction as a predictor of short term outcome in terms of adverse events& mortality during hospital stay. Methods: A total of 50 patients with first episode of ST elevation myocardial infarction without any conventional contraindication for thrombolysis were taken for the study. Based on the percentage resolution of ST segment at 90 min of thrombolysis, patients were divided into three groups. Complete resolution (>70%), Partial resolution (30-70%) and No resolution (<30%)..............

Keywords:Acute Coronary Syndrome (CAD), ECG, ST segment Elevation MI, ST segment resolution, Thrombolysis.

[1]. Elliott M. Antman᧨ Joseph Loscalzo , ST segment elevation myocardial infarction In: Longo DL, Kasper DL, Jameson JL, Fauci
AS, Hauser SL, Loscalzo J, editors. Harrison's Principles of Internal Medicine. 19th edition New York: McGraw-Hill Companies;
p.1599
[2]. Park K. Epidemiology of Chronic Non-Communicable Diseases And Conditions. In:Park K, editor. Textbook of preventive &
social medicine. 21 ed. Jabalpur(India):Bhanot;2011.p 338-9.
[3]. Ezzati M, Lopez AD, Rodgers A, et al. Comparative Quantification of Health Risks. Global and Regional Burden of Disease
Attributable to Major Risk Factors. Geneva:World Health Organisation; 2004.
[4]. Farrer M. Change in ST segment elevation 60 min after thrombolytic initiation predicts clinical outcome accurately as later
electrocardiographic changes. Heart1997;78:461-71.
[5]. Anthon K. Prognostic clinical significance of ST segment potential determined by body surface mapping in patients with acute
myocardial infarction. Circulation 1987;76(2):287

Abstract: Intestinal obstruction is one of the most common surgical emergency and associated with significant mortality and morbidity. Objective: The objective of this study is to identify the cause, mode of presentation, various modalities of treatment and outcome with least complications of acute intestinal obstruction. Materials and Methods: 50 patients who were admitted in the surgical ward with diagnosis of acute intestinal obstruction in Meenakshi Medical College & Research Institute over a period of two years i.e from July 2014 – August 2016 were taken randomly and managed..............

Keywords:Resection and anastomoses, Adhesions, Obstructed Hernia, Volvulus, Intussusception and Strangulation.

[1]. Michael ML Jr, Knapp L, et al. Acute intestinal obstruction; Comparative studies of small intestinal and colonic obstruction. Surg
1950; 28:90-110.
[2]. Becker WF. Acute obstruction of colon – An analysis of 205 cases. Surg. Gynaec. Obstet.1953.96: 677-82
[3]. Gill SS, Eggleston FC. Acute intestinal obstruction. Arch Surg 1965; 91:389-92.
[4]. Fuzan M, Kaymake E, et al. Principal causes of mechanical bowel obstruction in surgically treated adults in Western Turkey. BJS
1991; 78: 202-3.
[5]. Ramachandran CS. Intestinal volvulus. IJS 1989; 66-70.

Abstract: Background:A wide spectrum of organisms is responsible for neonatal septicaemia and is different in developed and developing countries. CASE CHARACTERISTICS: A single female term baby of birth weight of 2.2kg, small for gestational age (SGA) born to primigravida mother with meconium stained amniotic fluid by assisted vaginal delivery presented with respiratory distress since birth. Sepsis screen was positive and blood culture showed CedeceaLapagei.Chest X-ray showed features of Pneumonia. INTERVENTION: Based on this culture sensitivity report Inj. Ciprofloxacin was continued for 14days and Inj. amikacin was stopped at day 7. MESSAGE:Till date, CedeceaLapagei is an uncommon organism of Neonatal sepsis.

Keywords: CedeceaLapagei,Neonatalsepsis,Pneumonia.

[1]. Report of the National Neonatal Perinatal Database.National neonatology Forum, India, 2002-2003.
[2]. Grimont P.A.D., Grimont F, Farmer III J.J and Asbury M A.Cedeceadavisae gen. nov. sp. Nov. and
Cedecealapageisp.nov..newEnterobacteriaceafrom clinical specimens. International Journal of Systematic Bacteriology,1981. 31:
317-326.
[3]. Janda J, Michael, Sharon L. Abbott.TheEnterobacteria(2nded.) Washington D C.: ASM Press.2006.p.411. ISBN 978-1-55581-342-0.
[4]. Mawardi H, Pavlakis M, Mandelbrot D, Woo S. B. Sirolimus oral ulcer with Cedeceadavisaesuperinfection. Transpl Infect
Dis.2010, 12, 446-450.
[5]. Abate G, Qureshi S and Mazumder S A .Cedeceadavisaebacteemia in a neutropenic patient with acute myeloid leukema. Journal of
Infections2011, 63, 83-85.

Abstract: Objective: to describe the academic performance of substance abusing students in Abakaliki. Design: cross sectional Setting: school based study of adolescents. Participants:Six hundred and twenty senior secondary 2 and 3 students selected in a multi-staged sampling method were screened for substance abuse. Academic performance, school absence, psychosocial impairment of substance abusers was compared with those of their classmates matched for age, sex and socio-economic class. Outcome: Academic performance............

Keywords: academic performance, adolescents,school absences, substance abuse.

[1]. en.wikipedia.org/wiki/Academic_achievement (assessed 14th may 2012).
[2]. Dewey JD. "Reviewing the relationship between school factors and substance use for elementary, middle and high school students." J Prim Prevent 1999;19: 177-25.
[3]. Cox RG, Zhang L, Johnson WB, Bender DR. Academic performance and substance use: Findings from a state survey of public high school students. J Sch Health ASHA 2007; 77: 109-15.
[4]. Ingles CJ, Torregrosa MS, Rodriguez-Marin J, Garcia del Castillo JA, Gazquez JJ, Garcia-Fernandez JM, Delgado B. Alcohol and tobacco use and cognitive-motivational variables in school settings: effects on academic performance in Spanish adolescents. Adicciones 2013; 25: 63-70.
[5]. LukoyeA,Mungla PA, Ndung MN, Kinoti KC, Ogot EM. Prevalence of substance use among college students in Eldoret, Western Kenya. BMC Psychiatry 2011; 11: 34-38.

Abstract: Introduction:The vermiform appendix is considered by most to be a vestigial organ, its importance in surgery is only due to its tendency for inflammation resulting in the syndrome called acute appendicitis. Acute appendicitis is the most common cause of an "acute abdomen" in young adults. Appendectomy is the most frequently performed emergency abdominal operation. Present study was undertaken to study the clinical pattern of presentation and to analyze the difference in the anatomical, biochemical, microbiological, histological determinants in patients of perforated and non-perforated acute appendicitis...........

Keywords: Perforated appendicitis, Non-perforated appendicitis, Alvarado Score, Gangrenous appendicitis

[1]. Lewis FR, Holcroft JW, Boey J, Dunphy E. Appendicitis. A critical review of diagnosis and treatment in 1000 cases. Arch Surg.
1975;110(5):677-684.
[2]. Korner H, Sondenaa K, Soreide JA, Andersen E, Nysted A, Lende TH, Kjellevold KH. Incidence of acute non-perforated and
perforated appendicitis: age-specific and sex-specific analysis. World J Surg. 1997 Mar- Apr;21(3):313.
[3]. Livingston EH, Woodward WA, Sarosi GA, Haley RW. Disconnect between incidence of non-perforated and perforated
appendicitis: implications for pathophysiology and management. Ann Surg. 2007 Jun;245(6):886 PMID no 17522514
[4]. D A Hale, M Molloy, R H Pearl, D C Schutt, and D P Jaques. Appendectomy: a contemporary appraisal. Ann Surg. 1997 March;
225(3): 252-261
[5]. David Oliak, Dan Yamini, Vikram M. Udani, Roger J. Lewis, M.D., Hernan Vargas, M.D., Tracey Arnell, M.D., Michael J. Stamos,
M.D. Can perforated appendicitis be diagnosed preoperatively based on admission factors? al J GASTRO SURG 2000;4:470-474.

Abstract: Introduction: Vaginal discharge (safed pani in Hindi) is one of the leading symptoms for which the women seek care.The concept of safed paani is linked to ayurvedic beliefs about balance among the body dhatus.Safed pani is also widely attributed to heat.It is associated with a variety of psychological disorders.Vaginal discharge is one of the most common symptoms of gynaecological morbidity.Vaginitis is the most common cause followed by cervicitis.The aim of this study was to find out the perception of vaginal discharge among married females of reproductive age group................

Keywords: vaginal discharge,women,perception,rural areas.

[1]. Obeyesekere G.1976.The impact of ayurvedic ideas on the culture and the individual in Sri Lanka.In Asian Medical Systems.C.Leslie,ed,Berkeley:University of California Press.
[2]. Verma ,RKG,Rangaiyan R,Sikngh S,et al.(2001).A study of male sexual health problems in a Mumbai slum population,Culture Health and Sexuality3(3):339-352.
[3]. Bang R,BangA.1994.Womens perceptions of white vaginal discharge.Ethnographic data from rural Maharashtra.In listening to women talk about their health.issues and evidences from India.J.Gittelsohn et al ,eds,New Delhi:The Ford Foundation.pp:79-94.
[4]. Joshi AM,Dhapola,Pelto PJ.2008.Gynaecological problems :perception and treatment.seeking behaviours of rural Gujarati women.In Reproductive Health in India.New Evidence.MA Koenig,S Jeejeebhoy,JC Cleland,b Gantra.eds.pp:133-158.New Delhi.Rawat.

Abstract: Introduction: Solitary kidney individuals develop renal calculi just as the same as people with two kidneys. This study is about outcomes and complications associated with percutaneous nephrolithotomy in patients with solitary kidney . Material and Methods: Between January 2012 and JULY 2016 , 24 patients with a solitary kidney underwent PCNL at Department of Urology ,SVIMS , Tirupati . Routine laboratory tests including srerum creatinine , IVP , CT abdomen plain was performed on all patients. All patients were operated with the classic method of PCNL in prone position with fluoroscopic guidance . Renal function was assessed by serum creatinine and Estimated Glomerular Filtration Rate(calculated using MDRD formula) in preoperative period , post op day 1 and on 3 rd monthly follow up..........

Keywords: estimated glomerular filtration rate ,percutaneous nephrolithotmy , solitary kidney , serum creatinine .

[1]. Fernstorm I , Johansson B . Percutaneous pyelolithotomy . A new extraction technique . ScandJ Urol Nehrol . 1976 ; 10 : 257-259 .
[2]. Tiselius H.G ., Alken P ., Buck C et al: Guidelines on urolithiasis . Eur Assoc. Urol 2008 ; undefined .
[3]. Bucuras V., Gopal Krishnam G , Wolf J.S et al: The clinical research office of the endourological society Percutaneous Nephrolithotomy Global Study : Nephrolithotomy in 189 patients with solitary kidneys. J EndoUrol 2012 ; 26 : pp 336 – 34
[4]. Mahboub M.R., and Shakibi M.H . Percutaneous Nephrolithotomy in patients with solitary kidney . Urol J 2008 ; 5 :pp 24 -27 .
[5]. Segura JW , Preminger GM , Assimos DG et al . Nephrolithiasis clinical guidelines panel summary report on management of staghorn calculi . The American Urological association nephrolithiasis . Clinical Guidelines Panel . J Urol 1994 ; 151: 1648-1651.
[6]. Pardalidis NP , Smith AD . Complications of percutaneous renal procedures . in ; Smith AD editor controversies in endourology . st Philadelphia WB Saunders ; 1995 –p 179 .

Abstract: Aim: To evaluate the pH variation in the surrounding medium after the use of two different vehicles of calcium hydroxide-saline(aq.),propylene glycol and calcium hydroxide points over a period of 7 days as an intra-canal medicament. Materials and Methods: 40 extracted human premolars were decoronated and the canals were instrumented. A standardized external defects were prepared in the coronal third of the mesial surface of each tooth in order to simulate external root resorption. The samples were randomly divided into the 4 experimental groups (n = 10) according to the paste used for filling the root canals- Group I: The root canals were left empty and served as a control, Group II: The root canals were filled with a paste of calcium hydroxide powder and saline, Group III:........

Keywords:calcium hydroxide, calcium hydroxide points, external root resorption, intra-canal medicament, viscous vehicle.

[1]. Punit Fulzele et al. Evaluation of calcium ion, hydroxyl ion release and pH levels in various calcium hydroxide based intracanal
medicaments: An in vitro study. Contemporary Clinical Dentistry 2011 Oct-Dec; 2(4):291-295.
[2]. George GK, Rajkumar K, Sanjeev K, Mahalaxmi S. Calcium ion diffusion levels from MTA and apexcal in simulated external root
resorption at middle third of the root. Dent Traumatol 2009;25:480–3.
[3]. Charu Grover and Neeta Shetty et al. Evaluation of calcium ion release and change in pH on combining calcium hydroxide with
different vehicles. Contemp Clin Dent. 2014 Oct-Dec; 5(4): 434–439.
[4]. Silva LAB, Nelson-Filho P, Leonardo MR, et al. Effect of calcium hydroxide on bacterial endotoxin in vivo. J Endod 2002;28:94–8.
[5]. Duarte MAH, Nickolas V. Balan et al. Evaluation of pH and calcium ion release of calcium hydroxide pastes containing different
substances. J Endod 2012;38:834-837.

Abstract: Hormones play a critical role in breast carcinogenesis. Serum endogeneous sex steroid hormone levels (estradiol, progesterone and testosterone) of 30 confirmed cases of women with breast cancer and 40 healthy controls were analysed using the Enzyme Linked Immunofluoresence Assay (ELFA) method. Serum levels of estradiol were raised in the premenopausal and postmenopausal phases with statistically significant association of p<0.05. Serum values of progesterone and testosterone were statistically insignificant with
p>0.05. Concentration of serum estradiol may predict the risk for breast malignancy and hence may help the clinicians to decide further management to decrease breast cancer risk.

Keywords: Serum estradiol, progesterone, testosterone, breast malignancy

[1]. Eliassen A , Missmer S , Tworoger S , Spiegelman D, Barbieri R , Mitch Dowsett M et al. Endogenous Steroid Hormone
Concentrations and Risk of Breast Cancer Among Premenopausal Women. JNCI 2006;98(19):1406-15
[2]. Schernhammer E, Sperati F, Razavi P, Agnoli C, Sieri S, Berrino F, et al. Endogenous sex steroids in premenopausal women and
risk of breast cancer: the ORDET cohort. Breast Cancer Research 2013 15:R46
[3]. Sowers MF, Beebe J.L , McConnell D, Randolph J, and Jannausch M. Testosterone Concentrations in Women Aged 25–50
Years: Associations with Lifestyle, Body Composition, and Ovarian Status. Am J Epidemiol 2001;153:256-64
[4]. Arora M, Trehan A, Seth S and Chauhan A. Role of endogenous hormones in premenopausal females with breast carcinoma - a
pilot study in north Indian population. Internet Journal of Medical Update 2012 July;7:25-31
[5]. Sieri S, Krogh V, Bolelli G, Abagnato C, Grioni S, Pala V, et al. Sex Hormone Levels, Breast Cancer Risk, and Cancer Receptor
Status in Postmenopausal Women: the ORDET Cohort. Cancer Epidemiol Biomarkers 2009;18:169-76.

Abstract: Les adénomes à prolactine sont les plus fréquents des adénomes hypophysaires, leur association à la maladie de Fahr est rare.
Nous rapportant le cas d'un patient âgé de 35 ans, sans antécédents pathologiques notables, qui nous a été adressé pour exploration d'un processus hypophysaire découvert sur une tomodensitométrie(TDM) orbitaire demandée devant une baisse brutale de l'acuité visuel avec atteinte du champ visuel.L'imagerie par résonance magnétique (IRM) hypophysaire avait mis en évidence un macro-adénome hypophysaire avec présence des calcifications des noyaux gris centraux.Les explorations hormonales avaient conclu à une hyperprolactinémie tumorale avec une insuffisance anté-hypophysaire. Le bilan phosphocalcique était sans anomalies................

Keywords: Adénome hypophysaire, macroprolactinome, maladie de Fahr.

[1]. Delemer B. Adénomes à prolactine : diagnostic et prise en charge. Presse Médicale. 2009; 38: 117–124.
[2]. Chanson P, Young J. Actualités sur les prolactinomes. Annales d'Endocrinologie 77 (2016) 239–240.
[3]. Demas A, Godin M, Hannequin D, Nicolas G. Des calcifications cérébrales révélant un trouble du métabolisme phosphocalcique
génétique rare. Pratique Neurologique 2014;5:249–251.
[4]. Delgrange E, Trouillas J, Maiter D, Donckier J, Tourniaire J. Sex-related difference in the growth of prolactinomas: a clinical and
proliferation marker study. J Clin Endocrinol Metab 1997;82:2102-7.
[5]. Burlacu MC, Tichomirowa M, Daly A, Beckers A. Adénomes hypophysaires familiaux. Presse Médicale. 2009; 38: 112–116..

Abstract: Background: It is suggested that hyperthyroidism protects against thyroid malignancy. It was suggested that the incidence of malignancy is lower in toxic multinodular goiters than in non-toxic multinodular goiters. Recent studies show controversies. Material and methods: The aim of this study is to determine the incidence and type of thyroid carcinoma in toxic and nontoxic multinodular goiter in our country (Albania), through histopathological examination of thyroidectomy specimens............

Keywords: cold nodule (CN), differentiated thyroid carcinoma (DTC), Graves desease (GD), non toxic multinodular goiter (NMG), thyroid carcinoma (TC), toxic multinodular goiter (TMG).

[1] Mittendorf EA, McHenry CR. Thyroidectomy for selected patients with thyrotoxicosis. Arch Otolaryngol Head Neck Surg 2001; 127:61-5
[2] Rios A, Rodriguez JM, Balsalobre MD, Torregrosa NM, Tebar FJ, Parrilla P. Results of surgery for toxic multinodular goiter. Surg Today 2005; 35:901-6.
[3] Pazaitou –Panaiotou K, Michalakis K, Paschke R. Thyroid cancer in patients with hyperthyroidism. Horm Metab Res. 2012;44(4):255-262.
[4] McCall A, Jarosz H, Lawerence AM, et al. The incidence of Thyroid carcinoma in solitary thyroid nodule and multinodular goiter. Surgery 1986; 100:1128 -32. PMid: 3787469.
[5] K. Mukasa, J.Y. Noh,Y. Kunii, M. Matsumoto, S. Sato, S. Yasuda. Prevalence of malignant tumors and adenomatous lesions detected by ultrasonographic screening in patients with autoimmune thyroid diseases Thyroid, 21 (2011), pp. 37-41 Medline.

Abstract: Diabetes mellitus is a chronic disease (i.e. accompanies the patient for life) caused by the lack or shortage of secretion or the lack of effectiveness of insulin hormone produced by specialized cells in the pancreas. The basic function of insulin is to enable the body to make use of sugar as a fuel necessary for different activities and metabolic processes, so in the case of lack of insulin the body does not benefit optimally from sugar leading to the accumulation of large quantities in the blood. The accumulation of sugar leads instantly to symptoms such as increased urination, thirst and the feeling of tiredness, while in the long term it leads to diabetes complications such as chronic arteriosclerosis, renal failure, blindness, heart disease and limb amputation............

...................

Abstract: Root dilaceration is a dental anomaly characterized by an abnormal angulation of the dental root, which can cause problems during eruption and complications in the orthodontic and endodontic treatment or extraction. Dental anomalies have long been a concern to dental profession. Abnormalities in tooth size, shape, and structure result from disturbances during the morpho-differentiation stage of development, while ectopic eruption, rotation and impaction of teeth result from developmental disturbances in the eruption pattern of the permanent dentition . In addition, various maxillofacial pathologies can affect the jaw size, occlusion, diagnosis and treatment plan of orthodontic patients.............

[1]. Proffit WR. Contemporary orthodontics. C.V. Mosby Year Book; 1993.
[2]. White SC, Pharoah MJ. Oral radiology: principles and interpretation. 6th ed. St Louis: Mosby; 2009
[3]. Von Gool AV. Injury to the permanent tooth germ after trauma to the deciduous predecessor. Oral Surg Oral Med Oral Pathol.
1973;35:2-12
[4]. Hervas A, Forner L, Lena MC. Dental manifestations of systemic disease. Med Oral. 2000;5:109-17
[5]. Andreasen JO, Sundström B, Ravn JJ. The effect of traumatic injuries to primary teeth on their permanent successors. I. A clinical
and histologic study of 117 injured permanent teeth. Sc and J Dent Res. 1971;79:219-83..

Abstract: According to the 2005 histological classification of odontogenic neoplasms by the World Health Organization, ameloblastoma is a benign, locally invasive epithelial odontogenic tumor of putative enamel organ which usually affects the mandible. Unicysticameloblastoma (UA) refers to those cystic lesions that show clinical, radiographic, or gross features of a mandibular cyst, but on histologic examination show a typical ameloblastomatous epithelium lining part of the cyst cavity, with or without luminal and/or mural tumor growth. It accounts for 5-15% of all intraosseousameloblastomas. We report a case ofunicysticameloblastoma in a 15-year-old female, and review the literature.............

Keywords: Ameloblastoma; Radiolucency; Fine needle aspiration ;Unicysticameloblastoma

[1]. Agani, Z. et al., 2016. Maxillary unicystic ameloblastoma: a case report. BMC Research Notes, 9(1), p.469. Available at:
http://bmcresnotes.biomedcentral.com/articles/10.1186/s13104-016-2260-7.
[2]. Arora, S., 2015. Unicystic Ameloblastoma: A Perception for the cautious interpretation of radiographic and histological findings.
Journal of the College of Physicians and Surgeons Pakistan, 25(10), pp.761–764.
[3]. Chaudhry, A. et al., Extensive Type III Unicystic Ameloblastoma – A Case Report with Conservative Management. , (617),
pp.202–205.
[4]. Laxmidevi, B., Mohammed, M. & Ashok Kumar, K., 2015. Unicystic ameloblastoma with impacted third molar mimicking
dentigerous cyst. Journal of Interdisciplinary Dentistry, 5(1), pp.37–40. Available at:
http://www.jidonline.com/text.asp?2015/5/1/37/162743.
[5]. Nagalaxmi, V. et al., 2013. Unicystic mural ameloblastoma: an unusual case report. Case reports in dentistry, 2013, p.957418.
Available at: http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=3655499&tool=pmcentrez&rendertype=abstract