iosr-JDMS   Volume-17 ~ Issue-12 ~ December-2018

Abstract: Hypertensive disorders in pregnancy complicate 1 in 10 pregnancies, often associated with maternal and neonatal mortality and morbidity. It accounts for nearly one fifth of all maternal deaths. The only treatment for preeclampsia is delivery, which may lead to premature death. Despite the last two decades of research into this condition,the ability of clinicians to predict gestational hypertension/preeclampsia prior to the onset of symptoms has not improved remarkably. The purpose of this study is to Compare the efficacy of urine microalbuminuria and uterine artery Doppler resistance index in prediction of gestational hypertension/preeclampsia with sensitivity, specificity, positive predictive value and negative predictive value.

Keywords: Gestational hypertension, urine microalbuminuria, uterine artery Doppler

[1]. Mangal s puri et al,A study of uterine artery colour Doppler at 20-24 weeks gestation as a predictor of PIH & IUGR from industrial town in western india.RJPBCS.ISSN;0975-8585.jan-mar 2013.
[2]. K Fatema et al.,Role of urinary albumin in the prediction of preeclampsia,Faridpur med.coll.j.2011;6(1);14-18.
[3]. Montan S.Sjoberg O-O. Svenningsen. N. Hypertension in pregnancy—fetal and infant outcome. Clin Exp Hypertens –Hyper in Pregnancy 1987; B62: 337-348.
[4]. Paz I, Gale R, Laor A, Danon YL, Stevenson DK, Seidmans D, The cognitive outcome of full term small for gestational age infants at late adolescence. Obstet Gynecol 1995;85:452.
[5]. Piper JM, Xenakin CMJ, McFarland M, Elliot BD, Barkers MD, Langer D: Do growth retarded premature infants have different rates of perinatal morbidity and mortality than appropriately grown premature infants? Obstet Gynecol 1996;87:169...

Abstract: Cutaneous wound infection due to zygomycosis (mucormycosis) is an uncommon presentation. We report a case of Syncephalastrum recemosum in an immunocompetant male after a Post Achilles Tendon repair . The patient was successfully treated with I.V. Amphotericin B (liposomal) and a meticulous aseptic dressing.

Key words : Cutaneous Zygomycosis, Syncephalastrum recemosum, immunocompetant, I.V. Amphotericin B( liposomal)..

[1]. Chander J. Textbook of medical mycology, 3rd ed.New Delhi: Mehta Publishers; 2011. pp 361-386
[2]. Baby S , Ramya T.G. , Geetha R.K. . Onychomycosis by Syncephalastrum recemosum: Case report from Kerala, India . Dermatology Reports 2015;7:5527
[3]. Roden MM, Zaoutis TE, Buchanan WL, Knudsen TA, Sarkisova TA, Schaufele RL, et al. Epidemiology and outcome of zygomycosis: A report of 929 reported cases. Clin Infect Dis 2005;41:634-53.
[4]. Petrikkos G, Skiada A, Lortholary O, Roilides E, Walsh TJ, Kontoyiannis DP. Epidemiology and clinical manifestations of mucormycosis. Clin Infect Dis 2012;54:S23-34
[5]. Skiada A, Rigopoulos D, Larios G, Petrikkos G, Katsambas A. Global epidemiology of cutaneous zygomycosis. Clin Dermatol 2012;30:628-32.

Abstract: The traditional treatment of intra-abdominal liver abscess has been operative drainage as originally described by Volkmann in 1879. But during the last few decades, with the invention of newer radiological techniques like computed tomography (CT) and ultrasonography (USG), which are not only useful for accurate localization but also helpful in their safe aspiration and drainage of these abscess thus obviating the need for surgical intervention. The recent trend in management of liver abscesses has been shifted strongly toward nonsurgical methods. Several study have shown that a large proportion of patients can be treated with excellent results with a combination of parenteral (I/V) antibiotics and image-guided percutaneous treatment. Whether to perform percutaneous catheter drainage or intermittent..........

Keywords: Liver abscess, Percutaneous Needle Aspiration (PNA)' Percutaneous Pigtail Catheter Drainage(PCD)' Ultrasonography Guided Procedures, Antibiotic Therapy

[1]. Sharma MP, Ahuja V. Management of amebic and pyogenic liver abscess. Indian J Gastroenterology 2001; 20(Suppl 1):C33–6.
[2]. Thompson JE Jr, Forlenza S, Verma R. Amebic liver abscess: a therapeutic approach. Rev Infect Disease 1985;7: 171–9.
[3]. Thompson JE Jr, Forlenza S, Verma R. (1985) Amoebic liver abscess: a therapeutic approach. Rev Infect Dis 7:171–179.
[4]. Sherlock S, Dooley J. (1993) Diseases of the Liver and Biliary System, 9thedn. Oxford: Blackwell Science Publishing, pp. 471–502.
[5]. Huang CJ, Pitt HA, Lipsett PA, Osterman FA Jr, Lillemoe KD, Cameron JL et al. (1996) Pyogenic hepatic abscess: changing trends over 42 years. Ann Surg 223:600–607..

Abstract: Pelvic abscess is considered as one of the terminal complication of intra-abdominal or pelvic pathology which is extremely rare in male patients.1 This is a case report of intra-abdominal pelvic abscess in a male patient with unknown source and suspected atypical mycobacterial etiology. A 25 year old male chronic alcoholic presented with lower abdominal pain and distension for two weeks duration associated with on-off diarrhea, with no history of weight loss or anorexia. On examination, patient was hemodynamically stable and on per abdominal examination, there was a palpable supra pubic swelling associated with tenderness reaching upto umbilicus which was present even after catheterisation. Ultrasound showed pelvic collection which was confirmed to be pelvic abscess by CECT abdomen. Percutaneous drainage under ultrasound guidance was done and around 300ml of frank pus was drained out. Culture reports showed direct smear AFB positive even though no AFB growth was seen. Patient recovered uneventfully and was discharged with advice for regular follow up.

[1]. Saugat R, Kumari S, Chhabra M, Kapoor A. A case report: pelvic abscess by non-tubercular mycobacterium: a very unusual presentation. EJBPS. 2015 May 18;2(3):498-503.

[2]. Ansari P. Intra-Abdominal Abscesses - Gastrointestinal Disorders - MSD Manual Professional Edition. [online] MSD Manual Professional Edition. Available at: https://www.msdmanuals.com/professional/gastrointestinal-disorders/acute-abdomen-and-surgical-gastroenterology/intra-abdominal-abscesses [Accessed 13 Oct. 2018].

[3]. Benigno BB. Medical and surgical management of the pelvic abscess. Clinical obstetrics and gynecology. 1981 Dec;24(4):1187-97. [4]. Desai G, Ali S, Thomas S, Meena K, Aggarwal L, Kumar J. De novo pelvic abscess: An unreported primary presentation of Pott's spine. Annals of Tropical Medicine and Public Health. 2013 Nov 1;6(6):674.

[5]. Centers for Disease Control and Prevention (CDC. Updated guidelines for the use of nucleic acid amplification tests in the diagnosis of tuberculosis. MMWR. 2009 Jan 16;58(1):7.

Abstract: To compare the use of negative pressure wound therapy(NPWT) with negative pressure wound therapy with saline instillation(NPWTi) in cases of diabetic foot ulcers in terms of............

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Abstract: The incidence of sexual offence against women are increasing all over the world. The factors which predispose a woman to become a victim of these incidences are multiple. Understanding these risk factors is essential to prevent these offences. Among those risk factors, failure to suspect or identify potential perpetrator increase the chance of a woman to become a victim. The social relationship, shared between the victim and the perpetrator before the act of sexual offence are at times misleading and may bar the victim to suspect or identify potential perpetrator. In this background........

Keywords:Sexual offence, victim, accused, social relationship

[1]. Smith SG, Chen J, Basile KC, Gilbert LK, Merrick MT, Patel N, Walling M, Jain A. (2017). The National Intimate Partner and Sexual Violence Survey (NISVS): 2010-2012 State Report. Atlanta, GA: National Center for Injury Prevention and Control, Centers for Disease Control and Prevention
[2]. Preventing intimate partner and sexual violence against women: taking action and generating evidence. Geneva, World Health Organization, 2010.
[3]. Shankar Reddy Dudala, Arlappa N, An Updated Prasad's Socio Economic Status Classification for 2013. International Journal of Research and Development of Health. April 2013; Vol 1(2).
[4]. Park K, Park's Textbook of Preventive and Social Medicine, 21st Edition, 2011.
[5]. Tjaden P, Thoennes N (2006). Extent, nature, and consequences of rape victimization: findings from the National Violence Against Women Survey. Washington DC, US Department of Justice. Available at: www.ojp.usdoj.gov/nij/pubs-sum/210346.htm

Abstract: Back ground: A Drug-Related Problem is an event or circumstance involving drug therapy that actually or potentially interferes with desired health outcomes. When reviewing a patient's drug therapy, one of the main objectives of Clinical Pharmacist are to identify systematic review of each drug order on the patient's medication charts for its appropriateness and resolve any drug-related problems. Aim: To conduct a study on the identification of the drug related problems by Clinical Pharmacist. Method: A Prospective observational study was conducted for a period of 6 months and then patients were categorized according to their disease condition. Adverse drug reactions were identified and classified according to Naranjo's scale. Other drug related problems were analyzed from the prescription and referred from standard literature..........

Keywords: Adverse drug reaction, Clinical Pharmacist, Drug related Problems, Drug- Drug Interactions, Naranjo's causality assessment

[1]. PCNE Classification for Drug related problems, revised 29-05-06, V- 5.01, Pg.No:1-3.
[2]. G. Parthasarathi, "a textbook of clinical pharmacy practice-essential concepts & skills" (Orient Longman Private Limited Publishers; 2005, Pg.No:193-196)
[3]. Achyuth Kumar, V. Raghu Kumar, Akram Ahmad, G. P. Mohanta & P. K. Manna, Pharmacists Interventions and Pharmaceutical Care in an Indian Teaching Hospital, international journal of advanced research in pharmaceutical & bio sciences (ijarpb), 1(3), 2012, Pg.No:386-396.
[4]. Sonal Sekhar .C, Adheena Mary B, P.G. Anju B & Nishana Ameer Hamsa, Study on drug related hospital admissions in a tertiary care hospital in South India, Saudhi Pharmaceutical journal, 19(4), 2011, Pg.No:273-278.
[5]. Shankar PR Bajracharya. O, Gurung SB, Singh KK & Jha.N, Adverse drug reaction reporting in a pharmacovigilance centre of Nepal, Australasian Medical Journal [AMJ], 5(5), 2012,Pg.No:268-271.

Abstract: INTRODUCTION: Polycystic ovary syndrome(PCOS) may be associated with overweight and obesity,hyperandrogenism, insulin resistance and impaired glucose tolerance, anovulation and infertility and abnormal lipid profile. Aim of our study is to compare the efficacy of metformin and atorvastatin in treatment of PCOS. METHODS: A total of 108 patients suffering from polycystic ovary syndrome were recruited in this study according to Modified Rotterdam criteria. They were divided into equal three groups each comprising of 36 patients. They were given single blind (patient) treatment either with metformin (500mg twice daily) or atorvastatin (20mg once daily) or with both (metformin 500mg twice daily and atorvastatin 20mg once daily). The patients were followed up at the end of third.......

[1]. Stein IF, Leventhal ML. Amenorrhoea associated with bilateral polycystic ovaries. Am J. Obstet Gynecol 1935;29: 181-191.
[2]. LeonSperoff, Marc A. Fritz. Chronic Anovulation and the Polycystic Ovary Syndrome;ClinicalGynecologic Endocrinology and Infertility.Eighth edition;516.

[3]. LeonSperoff, Marc A. Fritz. Chronic Anovulation and the Polycystic Ovary Syndrome;ClinicalGynecologic Endocrinology and Infertility.Eighth edition;514.
[4]. Dunaif A. Hyperandrogenic anovulation (PCOS) : A unique disorder of insulin action qssociated with risk of non insulin dependent diabetes mellitus. AM J Med 1995; 98: 335.
[5]. Pasquali R,CasimimF,VenturoliS,ParadisiR,MattioliL,CapelliM,Melchionda N and Lobo G. Insulin resistance in patients with polycystic ovaries: its relationship to body weight and androgen level.Actaendocrinol 1983;104:110-106.

Abstract: Background: Burn wounds injuries continue to be prevalent and devastating form of trauma. People with burn wound are specially vulnerable to infections. The goal of systematic antibiotics is to prevent/treat infections. Infection of burn wound is a serious problem because it can delay healing, and invasive infections may lead to septicaemia that may result in the death of the patient. Antibacterial therapy is one of the several interventions that may prevent/treat burn wound infections and protect the burn patient from invasive infections which may lead to septicaemia and multiple organ failure. Objective: To access the pattern of microbial flora and sensitivity of systemic Antimicrobial Therapy in burn wound management......

Key Words: Burn, Pseudomonas aeruginosa, Staphylococcus aureus, Antibiotics, Methicillin-resistant staphylococcus aureus(MRSA),Extended-spectrum beta-lactamases (ESBL), Multi drug resistant(MDR)

[1]. Atiyeh BS, Gunn SW, Hayek SN. State of art in burn management. World J. Surg 2005;29:131-148.
[2]. Bang RL, Sharma PN, Sanyal SC, Najjdah IAI. Septicaemia after burn injury : a comparative study , Burns 2002:28:746-51.
[3]. Fitzwater J.Purdue GF, Hunt JL , O'Keefe GE . The risk factors and time course of sepsis and organ dysfunction afet burn trauma J. Trauma 2003:54;959-66.
[4]. Hunt JL, Purdue GF. The elderly burn patient. Am J Surg 1992;164:472-6.
[5]. Pruitt BA, Goodwin CW, Mason Jr D. Epidemiological, demographic, and outcome characteristics of burn injury. In: Herndon D, editor. Total Burn Care. London, England: Saunders; 2002. p. 6-30.

Abstract: Background: Platelet-rich concentrates are the most widely used regenerative biomaterials. Stimulation and acceleration of soft and hard tissue healing are due to local and continuous delivery of growth factors and proteins, mimicking the needs of the physiological wound healing and reparative tissue processes. This article aims to evaluate the clinical efficacy of open flap debridement (OFD) with or without platelet-rich fibrin (PRF) in the treatment of intrabony defects. Methods: Fifteen subjects with thirty intrabony defects were treated with either autologous PRF with open-flap debridement (test, n = 15) or open-flap..........

Keywords: Intrabony defect, open flap debridement, periodontal grafts, platelet rich fibrin, reconstructive osseous surgery

[1]. Karring T, Lindhe J, Cortellini P. Regenerative periodontal therapy. In: Lindhe J, Karring T, Lang NP, editors. Clinical Periodontology, and Implant Dentistry. Copenhagen: Blackwell Munksgaard; 2003. pp. 650–704.

[2]. Polimeni G, Xiropaidis AV, Wikesjö UM. Biology and principles of periodontal wound healing/regeneration. Periodontol 2000. 2006;41:30–47. [PubMed]

[3]. Zander HA, Polson AM, Heijl LC. Goals of periodontal therapy. J Periodontol. 1976;47(5):261–6. [PubMed]

[4]. Pradeep AR, Shetty SK, Garg G, Pai S. Clinical effectiveness of autologous platelet-rich plasma and platelet-rich fibrin in intrabony defect treatment. J Periodontol. 2009;80:62–71.[PubMed]

[5]. Siciliano VI, Andreuccetti G, Siciliano AI, Blasi A, Sculean A, Salvi GE. Clinical outcomes after treatment of non-contained intrabony defects with enamel matrix derivative or guided tissue regeneration: A 12-month randomized controlled clinical trial. J Periodontol. 2011;82(1):62–71. [PubMed]

Abstract: Introduction: Initial histopathological analysis of a pulmonary lesion is mandatory when ever a bronchogenic carcinoma is suspected in order to determine the diagnostic and management strategy. The 2 main methods to obtain adequate samples are flexible fibreoptic bronchoscopy and Computed Tomography (CT) guided biopsy. Aims And Objectives: To determine the test performance characteristics of various modalities ie. Bronchoscopy guided, CT guided procedures for histopathological specimen and to determine the Type of cancer.Materials And Methods:Bronchoscopy Guided-Bronchial washings, Bronchial brushings, Endobronchial biopsy, Trans bronchial needle aspiration and Fine........

Key words: Bronchogenic carcinoma, Flexible fibreoptic bronchoscopy, FNAC, CT guided biopsy.

[1]. Arora VK, Seetharaman ML, Ramkumar S, Mamatha TV, Subbarao KSVK, Banerjee A et al. Bronchogenic carcinoma, Clinicopathological pattern in South Indian Population. Lung India. 1990; 8(3): 133-136
[2]. Johnston WW, Elson CE. Comprehensive cytopathology. Respiratory tract. In: Bibbo M, editor. 2nd ed. Philidelphia: W. B. Saunders company.1997; 2: 325-401.
[3]. Ernst and D. Anantham. Bronchus sign on CT scan discovered. Chest. 2010;138(6): 1290–1292.
[4]. Wongsurakiat P, Wongbunnate S, Dejsomritrutai W, Charoenratanakul S, Tscheikuna J,Youngchaiyud P. et al. Diagnostic value of bronchoalveolar lavage and Postbronchoscopic sputum cytology in peripheral lung cancer. Respirology, 1998; 3:131-7.
[5]. Gaur DS, Thapliyal NC, Kishore S, PathakVP. Efficacy of broncho-alveolar lavage and bronchial brush cytology in diagnosing lung cancers. 2007; 24(2): 73-77.

Abstract: Telepathology in India is still in the evolving stages. Although, much progress has been made around the world specially in the field of digital imaging and virtual slides, the practice of telepathology in India still revolves around static telepathology, be it in telelearning or distance learning, or in remote diagnosis. Websites such as telepathology.org.in have been very successful in popularizing telepathology through quizzes of interesting and rare cases. The only study of teleconsultation from India, has shown that a good concordance with glass slide and static telepathology images. The reasons for the relative delay in acceptance of telepathology in India are manifold..

Keywords: Acceptance, India, successes, telepathology

[1]. MedicineNet.com: MedTerms medical dictionary [Internet]. San Clemente (CA): MedicineNet; c1996-2009. Definition of telepathology; 2004 [cited 2010 Jun 20]. Available from: http://www.medterms.com/script/main/art.asp?articlekey=33621
[2]. Furness P. A randomized controlled trial of the diagnostic accuracy of internet-based telepathology compared with conventional microscopy. Histopathology. 2007 Jan;50(2):266-73.
[3]. Weinstein RS, Graham AR, Richter LC, Barker GP, Krupinski EA, Lopez AM, et al. Overview of telepathology, virtual microscopy, and whole slide imaging: prospects for the future. Hum Pathol. 2009 Aug;40(8):1057-69.
[4]. Moqadem K, Pineau G. Summary: telepathology: guidelines and technical standards, literature review [Internet]. Montreal: Agence d'Evaluation des Technologies et des Modes d'Intervention en Sante (AETMIS); 2008. [cited 2010 Jun 29]. Available from: http://www.aetmis.gouv.qc.ca/site/phpwcms_filestorage/e520c4569179a2999ae600c8d38 be465.pdf 5. Krupinski EA. Virtual slide telepathology workstation-of-the-future: lessons learned from teleradiology. Seminars in Diagnostic Pathology. 2009;26(4):194-205.

[5]. Weinstein, RS (1986), "Prospects for telepathology (Editorial)", Hum Pathol, 17 (5): 433–434,doi:10.1016/s0046-8177(86)80028-4

Abstract: Introduction: Since the advent of laparoscopic technique of surgery majority of hernioplasties are performed laparoscopically. The purpose of this surgery is to compare laparoscopic hernia repair with the open repair. There is less postoperative pain and early mobilization of the patient in laparoscopic hernioplasty than the open technique. Materials and Methods: this study is carried out in Department of General Surgery, Maheshwara Medical College and Hospital, Isnapur, Hyderabad. A total of 80 patients were included, who were then divided into two study groups containing 40 patients in each group. each patient was included into respective group of their choice after explaining both.........

Key Words: TAPP, open repair, open Lichtenstein

[1]. Katri KM. Open preperitoneal mesh repair of recurrent inguinal hernia. Hernia 2009;13(6):585–589 13.
[2]. Kouhia STH, Huttunen R, Silvasti SO, Heiskanen JT, Ahtola H, Uotila-Nieminen M et al. Lichtenstein hernioplasty versus totally extraperitoneal laparoscopic hernioplasty in treatment of recurrent inguinal hernia–a prospective randomized trial. Ann Surg 2009;249(3):384–387.
[3]. Neumayer L, Giobbie-Hurder A, Jonasson O, Fitzgibbons RJ, Dunlop D, Gibbs J et al. Open mesh versus laparoscopic mesh repair of inguinal hernia. N Engl J Med 2004;350(18):1819-1827
[4]. Schmedt CG, Sauerland S, Bittner R. Comparison of endoscopic procedurs vs Lichtenstein and other open mesh techniques for inguinal hernia repair: a meta-analysis of randomized controlled trials. Surg Endosc 2005;19(2):188-199.
[5]. Eklund A, Rudberg C, Leijonmarck CE, Rasmussen I, Spangen L, Wickbom G et al. Recurrent inguinal hernia: randomized multicenter trial comparing laparoscopic and Lichtenstein repair. Surg Endosc 2007;21(4):634–640.

Abstract: Aims and Objective: To find out the presence of obsessive – compulsive disorder in patients with schizophrenia and to find out there clinical and demographic difference. Methods: Study consisted of 82 subjects including male/female who fulfill ICD10 criteria for schizophrenia and assessed by applying appropriate rating scales including Positive and Negative syndrome scale ( PANSS) for schizophrenia . The Yale Brown Obsessive Compulsive Scale (Y-BOCS) was then used in those subjects who fulfill ICD 10 criteria for OCD and to determine presence and severity of any OCD symptoms. Result: In the individuals with schizophrenia with OCD was 23.1%. And subjects shows higher score on YBOCS and PANSS negative symptoms were lower as compared to schizophrenia alone. fear of contamination (36.8 %) and fear of harming oneself or other was (26.3%) . And among compulsions cleaning/washing was(31.5%) while checking and counting was ( 21.0%).

Key Words: About five key words in alphabetical order, separated by comma

[1]. Michael Poyurovskya,e, Sophia Hramenkovb, Victoria Isakovb. Obsessive compulsive disorder in hospitalized patients with
chronic schizophrenia. Psychiatry Research 102 2001 4957.
[2]. Sterk B, Lankreijer K, Linszen DH, De Haan L. Obsessive compulsive symptoms in first episode psychosis and in subjects at ultra
high risk for developing psychosis; onset and relationship to psychotic symptoms. Aust N Z J Psychiatry. 2011;45:400–406.
[3]. Michael poyurovsky, joseph Zohar, Ira Glick. Obsessive compulsive symptoms in schizophrenia: implication for future psychiatric
classifications. Comprehensive psychiatry 53 (2012) 480-483.
[4]. Rosen I. The clinical significance of obsessions in schizophrenia. J Ment Sci 1957; 103 (433):773-85.
[5]. Buckley PF, Miller BJ, Lehrer DS, Castle DJ. Psychiatric comorbidities and schizophrenia. Schizophr Bull. 2009;35: 383–402.