iosr-JDMS   Volume-17 ~ Issue-12 ~ December-2018

Abstract: Aims: To evaluate the relationship of Neutrophil toLymphocyte ratio in pregnant women withPreeclampsia and to investigate whether Neutrophil to Llymphocyte ratio has a role in predicting preeclampsia. Patients and methods:This study was conducted in Niloufer hospital,mother and child health care unit, Osmania medical college Hyderabadfrom August2016 to August 2017.This case-control study was conducted on 108 healthy pregnant women and 108 pregnant women with pre-eclampsia. Among 216 cases and controls 16 women were excluded based on exclusion criteria.
Results: The median NLR value of the preeclampsia group was significantly higher than that of the control group [7.39 ± 3.51 vs. 3.20±1.08; p<0.001]. Conclusion: Given that this study has shown..........

Keywords: Neutrophil to Lymphocyte ratio, preeclampsia,pregnant women

[1]. ACOG report of task force of hypr tension in pregnancy Obstetgynecol 122:1122,2013b
[2]. Ramma W, Ahmed A. Is inflammation the cause of preeclampsia?BiochemSoc Trans 2011;39:1619–27
[3]. Akira, S., S. Uematsu, and O. Takeuchi. Pathogen recognition and innate immunity. Cell 2006.124:783–801.
[4]. prasmusinto et al neutrophil-lymphocyte-ratio-and-red-cell-distribution-width-as-a-predictor-of-preeclampsia-a-retrospective-study-2376-127X-1000307.pdf. Journal of Pregnancy and Child Health.volume 4 issue 2.
[5]. Gezer C, Ekin A, Ertas IE, Ozeren M, Solmaz U, Mat E, et al. High first-trimester neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios are indicators for early diagnosis of preeclampsia. Ginekol Pol. 2016;87(6):431–5..

Abstract: Background: Decades of clinical research have established that Acute Pain after surgery has a distinct Pathophysiology that reflects peripheral and central sensitisation as well as humeral factors contributing to pain at rest and during movement, this can impair functional ability and often cumulates in delayed recovery. General Anesthesia involves stressful events at various stages, the most stressful situations are seen during the period of induction, intubation and extubation. Since 1950 Hypertension, Tachycardia has been recognised as commonly associated under light planes of Anesthesia and stressful period. Different techniques with different.......

Keywords: Dexmedetomidine, Lignocaine, Pressor response, Hemodynamic changes, Narcotics, Rescue Analgesia, Numerical Pain Score and Pain-free period.

[1]. Burstein Cl , Lopinto FJ and Newman W : Electrocardiographic studies during endotracheal intubation, Effects during usual routine technics, Anaesthesiology 1950 March, 11(2): 224-37.
[2]. Stoelting RK: Circulatory changes during direct laryngoscopy and tracheal intubation. Influence of duration of laryngoscopy with or without prior lidocaine. Anaesthesiology 1977, 47:381-383.
[3]. Clayton DG , Allt Graham J. Intravenous lignocaine in dental anaesthesia. The effect of pretreatment on the incidence of dysrhythmias. Anaesthesia 1983, 38: 1066-1070.
[4]. Stanley Tam MD FRCP, Frances Chung MD FRCP and Michael Campbell MD FRCP. Intravenous lignocaine: optimal time for injection before tracheal intubation. AnesthAnalg 1987;66: 1036-1038.
[5]. Wu CT, Borel CO, Lee MS, Yu JC, Liou HS, Yi HD, et al. The interaction effect of perioperative cotreatment with dextromethorphan and intravenous lidocaine on pain relief and recovery of bowel function after laparoscopic cholecystectomy. AnesthAnalg. 2005;100:448–53. [PubMed: 15673874]

Abstract: The human periodontium and dental pulp cavity are closely connected by their proximity and by the presence of apical and lateral radicular foramina, which permit the passage of pathogens between these two distinct anatomical areas. The interrelationship between endodontic and periodontic lesion has been a subject of speculation, confusion and controversy for many years. Pulpal and periodontal problems are responsible for more than 50% of tooth mortality today. An endo-perio lesion can have a varied pathogenesis which ranges from quite simple to relatively complex one. When a periapical lesion communicates with a deep periodontal pocket, the etiology can be either endodontic or periodontic. The purpose of this review paper is to explain the nature of that relationship. Successful therapy will only result from the establishment of an accurate diagnosis and forming such a diagnosis requires a methodical multi-staged approach.

Keywords: Endo-perio lesions, Periodontal, Pulpal, Diagnosis

[1]. Khan R.N., Kumar A., Chadgal S. Majid Jan S. ENDO-PERIO INTERRELATIONSHIP- AN OVERVIEW. International Journal of Information Research and Review. 2017.;04(3)-3895-3898.

[2]. Simring M, Goldberg M. The pulpal pocket approach: retrogradeperiodontitis. J Periodontol 1964; 35: 22-48.

[3]. Meshack RA. Tavane P. Srinivasa TS .Guru R. A Systematic review of Effectiveness of Combined Perio – Endo Interventions . J. Adv Oral Research 2011;2(3):5-9.

[4]. Pitt Ford TR. Harty's Endodontics in Clinical Practice. 5th Edition 2009; 215

[5]. Rotstein I. Simon JH. The endo-perio lesion: a critical appraisal of the disease condition. Endodontic Topics 2006, 13, 34–56

Abstract: The study was conducted in District Hospital Baramulla from January 1, 2015, to December 31, 2016. It was a post-operative interventional study. In this study, 100 eyes of 100 patients with primary nasal pterygium were operated, 65 males and 35 females. Simple excision under local anesthesia was performed followed by closure of bare sclera by conjunctival autograft. The conjuctival autograft was sutured by three releasable (10-0 Nylon) sutures, single pass three throw loop knot with long ends, one each at upper and lower limbal corner, third one at middle of graft on nasal side. The three surtures were removed on third postoperative day by pulling the long end of the knot. Follow up period was six months. Recurrence occurred in one patient (1%), other complications include subconjuctival hemorrhage/ sub graft hemorrhage in twelve patients (12%), conjuctival chemosis in nine patients (9%), graft retraction from nasal side in four patients (4%), overriding of graft on cornea in three patients (3%) and granuloma in donor site in one patient (1%)

[1]. Kim HH, Mun JH, Park YJ, Lee KW, Shin PJ. Conjuctivolimbal autograft using a fibrin adhesive in pterygium surgery Korean J Opthalmol 2008;22:147-54.
[2]. Hall RC, Logan AJ, Wells AP. Comparison of fibrin glue with sutures for pterygium excision surgery with conjunctival autografts. Clin Exp Ophthalmol 2009;37:584-9.
[3]. Panda A, Kumar S, Kumar A, Bansal R, Bhartiya S. Fibrin Glue in ophthalmology Indian J opthalmol 2009;57:37, 1-9.
[4]. Goswami S, Chatterjee SS, Goswami S, Bhaduri G. A comparative study of use of fibrin glue and vicryl suture in conjuctival autograft transplantation following pterygiym excision. Indian J Basic Appl Med Res 2014;4:169-75.
[5]. Yuksel B, Unsal SK, Onat S. Comparison of fibrin glue and suture technique in ptergium surgery peformed with limbal autograft. Int J Opthalmol 2010;3:316-20.

Abstract: Introduction: Diabetes mellitus (DM) is the most common metabolic disease and its prevalence is increasing rapidly. Studies have reported that there is thyroid dysfunction in Type 2 Diabetes Mellitus patients. Subclinical hypothyroidism (SCH) is the most common in diabetes mellitus patients. The present study aims to evaluate the subclinical hypothyroidism in type 2 diabetes mellitus patients. Materials & methods: This, cross sectional case-control study, conducted in Department of Physiology in association with Department of Endocrinology, JNU Institute for Medical Sciences & Research Center, Jaipur. A total of 45 ambulatory type 2 diabetes mellitus patients were taken as cases..........

Keywords: Diabetes mellitus, Hypothyroidism, Glycated hemoglobin

[1]. Shokoufeh B and Bahareh Z. Is there Correlation between Subclinical Hypothyroidism and Diabetic Nephropathy?. Austin J NephrolHypertens. 2017; 4(3):1-4.
[2]. Harati H, Hadaegh F, Saadat N, Azizi F. Population-based incidence of Type 2 diabetes and its associated risk factors: results from a six-year cohort study in Iran. BMC public health. 2009; 9:186.
[3]. M.Vijayalakshmi, R.Mahalakshmi, R.Shanthi. Prevalence of Sub-clinical Hypothyroidism in Type 2 Diabetes Mellitus.Stanley Medical Journal. 2016;3(4):5-10.
[4]. Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA. 2004;291(2):228–38.
[5]. S. Shabnam, C.R. Mallikarjuna, Peersab M Pinjar. Study of subclinical hypothyroidism among patients with type 2 diabetes mellitus. ClinSci Res 2015;4:195-8..

Abstract: Background: Vacuum assisted closure dressing is a recent trend and proven method for faster healing of chronic non healing ulcers. Delayed wound healing is a significant health problem imposes social and financial burdens. Vacuum-assisted closure (VAC) therapy has been developed as an alternative to the standard forms of wound management, which incorporates the use of negative pressure to optimize conditions for wound healing and requires fewer painful dressing changes. Aim: To compare the efficacy of the modified vacuum assisted closure (VAC) dressing using gloves and available resources in a low resource setting with routine Povidone iodine dressing in wound healing in patients who are admitted in GRH,MADURAI.........

[1]. Fleischmann W, Strecker W, Bombelli M, Kinzl L. Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg 1993;96:488-92.
[2]. KCI VAC, 2014. Available from: http://www.kci1.com/KCI1/
[3]. educationtraining. [Last accessed on 2014 Nov 11].
[4]. Danu M, Rosadi S. The simplest modified vacuum assisted closure to treat chronic wound: Serial case report. J Plastik Rekonstruksi 2012;1:117-22.
[5]. Singh M, Singh R, Singh S, Pandey V, Singh D. Vacuum assisted closure in wound management – Poor man's VAC. Int J Plast Surg 2008;6...

Abstract: Background: Malaria in Goa is showing a decreasing trend. Most of the malaria cases are found in areas around construction projects. Hence it is important to understand the Knowledge, attitude and practices amongst construction workers about malaria; in order to achieve elimination. Aims and Objectives: To study the knowledge, attitude and practices amongst construction workers regarding the prevention, spread and control of malaria and to assess the status of health cards amongst these construction workers.Materials and Methods: The demographic and the knowledge, attitude and practice towards malaria was assessed using a prestructured questionnaire made from previous studies. Focus group discussions and open ended interviews were also conducted. Results: The knowledge..........

Keywords: Malaria, Goa, Construction Workers, Health Cards

[1] Kumar A, Chery L, Biswas C, Dubhashi N, Dutta P, Dua VK, Kacchap M, Kakati S, Khandeparkar A, Kour D, Mahajan SN, Maji A, Majumder P, Mohanta J, Mohapatra PK, Narayanasamy K, Roy K, Shastri J, Valecha N, Vikash R, Wani R, White J, Rathod PK: Malaria in South Asia: prevalence and control.Acta Trop 2012, 121:246-255.

[2] Tyagi P, Roy A, Malhotra MS. Knowledge, awareness and practices towards malaria in communities of rural, semi-rural and bordering areas of east Delhi (India). J Vector Borne Dis. 2005;42:30–5.

[3] Keating J, Eisele TP, BeNEt A, Johnson D, Mcintyre K. A description of malaria-related knowledge, perceptions, and practices in the Artibonite Valley of Haiti: implications for malaria control. Am J Trop Med Hyg. 2008;78:262–9.

[4] Simsek Z, Kurcer MA. Malaria: knowledge and behaviour in an endemic rural area of Turkey. Public Health. 2005;119:202–8.

[5] A Lindblade, Kim & Steinhardt, Laura & Samuels, Aaron & Patrick Kachur, S &Slutsker, Laurence. (2013). The silent threat: Asymptomatic parasitemia and malaria transmission. Expert review of anti-infective therapy. 11. 623-39. 10.1586/eri.13.45..

Abstract: The association of Sella turcica bridging calcification & midfacial skeleton has been an area of interest for researchers. Based on evidence of common embryologic origin between sella turcica and mid facial skeleton, the aim was to determine an association between sella turcica bridging and facial growth pattern. 60 pretreatment lateral cephalograms were divided into horizontal & vertical facial growth pattern of 30 each and were traced manually with conventional method. Lateral Cephalograms were evaluated by angular measurements (SN-GoGn) to determine facial growth pattern. Sella turcica was calculated using linear measurements. To evaluate & quantify the level of sella turcica bridging, standard scoring scale by Leonardi et al was used. The calculated...........

[1]. Sandham A. Cervical vertebral anomalies in cleft lip and palate. Cleft Palate J 1965;36:273-81.
[2]. Leonardi R, Barbato E, Vichi M, Caltabiano M. Skeletal anomalies and normal variants in patients with palatally displaced canines. Angle Orthod 2009;79:727-32.
[3]. Ali B, Shaikh A and Fidac M. Association between sellaturcica bridging and palatal canine impaction.Am J Orthod. 2014;146:437-41.
[4]. Kjer I, Fischer BH, Reintoft I, Keeling JW. Pituitary gland and axial skeletal malformations in human foetuses with spinal bifida. Eur J OediatrSurg 1999;9354-358
[5]. Miletich I, Sharp PT. Neural crest contribution to mammalian tooth formation. Birth Defects Res C Embryo Today 2004;72:200-212...

Abstract: High Energy Radiation causes most damage to the rapidly dividing cells, therefore it is useful in treatment of cancer because tumor cells divide extreme rapidly. (Several mechanisms can be used to deliver radiations to tumor by modern treatment planning systems on the basis of radiation dose planning). The goal of radiation therapy is to deliver a therapeutic radiation dose to target tissue organs while minimizing the risk of normal tissue complications by evaluating biological based 3D treatment planning. The purpose of present work is to study the effective use of equivalent uniform dose (EUD) based optimization in volumetric modulated arc radiation treatment (VMAT) plans.........

Keywords: Dose planning, EUD, TPS, DV-optimization, dose evolution parameters

[1]. Prostate cancer. [Internet] [place unknown] : National Cancer Institute [last cited on 2018 July 10].
[2]. Pollack A, Zagars Gk, Starkschall G, Antolak JA, Lee JJ, Huang E, et al. prostate cancer radiation dose response : Results of the M.D. Anderson phase-III randomized trail. Int J. Rad at oncol Biol Phys 2002; 53; 1097-105.
[3]. Zietman AL, Desilvio ML, Slater JD, Rossi CJ Jr, Miller DW, Adams JA, et al. comparison of conventional dose Vs. high-dose conformed radiation therapy in clinically localized adenocarcinoma of the prostate. A randomized controlled trail JAMA 2005, 294; 133-9.
[4]. Niemierko A. Reporting and analyzing dose distributions : a concept of equivalent uniform dose. Med phys 1997:24; 103.
[5]. Niemierko A. A generalized concept of equivalent uniform close (EUD). Med phys 1999;26, 1100...

Abstract: Aims and objectives: To identify lesions with cystic appearance in pancreas, to differentiate between pancreatic cystic lesion of neoplastic etiology after exclusion of pseudocyst due to pancreatitis, to differentiate cystic lesion into benign and malignant nature based of CECT morphology, to correlate histopathological reports with CECT morphology. Materials and methods: It was a non-interventional prospective observational study in the department of radiology of Seth G.S. medical college and KEM hospital Mumbai.Patients meeting the inclusion criteria were studied over a period of 12 months. All patients who underwent contrast enhanced CT scan abdomen as advised by the respective physician/surgeon for further evaluation of already diagnosed pancreatic lesion or suspected cystic pancreatic lesionwere included in study..........

Keywords: Cystic pancreatic lesions, contrast enhanced CT scan (CECT), histopathological correlation

[1]. Farrell JJ. Prevalence, diagnosis and management of pancreatic cystic neoplasms: Current status and future directions. Gut Liver. 2015;9(5):571–89.

[2]. Kimura W, Nagai H, Kuroda A, Muto T EY. Analysis of small cystic lesions of the pancreas. Int J Pancreatol. 1995; 18:197–206. [3]. Sahani D V, Kadavigere R, Saokar A, Fernandez-del Castillo C, Brugge WR, Hahn PF. Cystic pancreatic lesions: a simple imaging-based classification system for guiding management. Radiographics. 2005;25(6):1471–84.

[4]. Sahani D V., Kambadakone A, MacAri M, Takahashi N, Chari S, Fernandez-Del Castillo C. Diagnosis and management of cystic pancreatic lesions. Am J Roentgenol. 2013;200(2):343–54..

Abstract: Background Tuberculosis (TB) is a disease of major public health concern especially in Africa where there is significant upsurge because of the HIV epidemic. It is also the commonest cause of death in AIDS patients. The risk of development of active TB in HIV-infected individuals is 20-37 times higher than those that are HIV negative. Studies have reported that knowledge, attitude and practice (KAP) regarding tuberculosis among HIV patients is poor and has been associated with high transmission. A review of available literature of studies on KAP regarding TB among HIV patients have recommended a health education intervention that is specific and directed at this high risk group. This paper outline the study protocol to evaluate the effectiveness of a new developed health education intervention module in improving knowledge, attitude and practice among HIV patients in Nigeria..........

Keywords: Health education intervention, knowledge, attitude, practice, tuberculosis, HIV patients

[1]. .Abebe R, Demissie M. Assessment of knowledge and practices related to tuberculosis and associated factors among HIV positive people in Addis Ababa, Ethiopia.Global Journal of Medicine and Public Health2012; 1(2):35-42

[2]. Cornman DH, Kiene SM, Christie S, Fisher WA, Shuper PA, Pillay S, Friedland GH, Thomas CM, Lodge L, Fisher JD. Clinic-based intervention reduces unprotected sexual behavior among HIV-infected patients in KwaZulu-Natal, South Africa: results of a pilot study. Journal of acquired immune deficiency syndromes 2008; 48(5):553. [3]. Fisher .J.D., Laramie S. (2009). Secondary Prevention of HIV Infection: the current State of prevention for positives. Curr Opin HIV and AIDS. 4(4): 279–287.
[4]. FMOH. (2013). Nigeria Stop TB Partnership Strategic plan 2013-2015.
[5]. Gouda, S., Peerapur, B., Rudramma, J., Kaleem, a, & Sandhya, R. (2014). A study to determine and compare the knowledge, attitude and compliance of Tuberculosis treatment among HIV seropositive and HIV seronegative TB patients. BMC Infectious Diseases, 14(3), 9..

Abstract: Though clitoromegaly is common,its association with Neurofibromatosis is extremely rare. In this case report a female presented to our OPD with painless clitoromegaly associated with features of Neurofibromatosis 1 for the past 15 years. Her hormonal and radiological profile was normal. Features of Neurofibromatosis were plexiform neurofibroma, cafe au lait macules and axillary freckles.

Keywords: Clitoromegaly, Neurofibromatosis, Plexiform neurofibroma, Cafe au lait macules

[1]. Griebel ML, Redman JF, Kemp SF, Elders MJ. Hypertrophy of clitoral hood : presenting sign of neurofibromatosis in female child. Urology. 1991;37:337-9.
[2]. Cost, N.G., F.S. Sanchez, A.G. Weinberg, K. Koral, and L.A. Baker. 2009. Neurofibromatosis presenting as painless clitoromegaly. Urol. J. 6: 220-222.
[3]. Jamie AM. Massie, Judith Lacy. Plexiform Neurofibroma Presenting as Clitoromegaly: Case report and review of the literature. 2008; 21(2):97.
[4]. Haddad HM, Jones HW Jr. Clitoral enlargement simulating pseudohermaphroditism. AMA J Dis Child. 1960;99:282-7.
[5]. Kaneti J, Lieberman E , Moshe P, Carmi R. A case of ambiguous genitalia owing to neurofibromatosis- review of the literature. J Urol. 1988;140:584-5..