iosr-JDMS   Volume-20 ~ Issue-11 ~ November 2021

Abstract: Resume Au milieu du 20ème siècle, l'unique traitement d'une tumeur osseuse était l'amputation. Actuellement, la chirurgie prothétique de reconstruction a permis d'améliorer le pronostic et la qualité de vie du patient. L'objectif de notre travail est d'étudier la contribution des prothèses de reconstruction lors de la chirurgie tumorale dans l'amélioration de la qualité de vie des patients, d'énumérer leurs indications, leurs intérêts, ainsi que les résultats des patients opérés, au sein de notre formation. Notre étude porte sur 4 cas de tumeurs osseuses traitées par prothèse de reconstruction chirurgicale, au sein du service de Traumatologie-Orthopédie II de l'Hôpital militaire......

[1]. Prise en charge des tumeurs osseuses malignes autour du genou. T.RED.Fleury-H.H.Miazzari- P.J.Hoffmeyer. RevMed Suisse 2014 ; 10 ; 24038.
[2]. P. Journeau , G. Dautel , P. Lascombes Prise en charge chirurgicale des tumeurs osseuses chez l'enfant. Annales Françaises d'Anesthésie et de Réanimation.
[3]. Zoubir KARA service d'orthopédie CHU de Blida- Algérie Traitement conservateur des tumeurs osseuses malignes primitives des membres (2009) PP. 2 à 93
[4]. Evans S, et al. Megaprostheses in the management of trauma of the knee, J Orthop. (2015)
[5]. Melican MC, Zimmerman MC, Dhillon MS, Ponnambalam AR, Curodeau A,Parsons JR. Three- dimensional printing and porous metallic surfaces: a neworthopedic application. J Biomed Mater Res. 2001 May; 55(2):194-202. PMID:11255171

Abstract: Gingival fibromatosis (GF) is a rare and benign genetic pathology, characterized by a slow and progressive fibrous hyperplasia of the marginal, attached and papillary gingiva. Its appearance is most often related to the eruption of temporary and/or permanent teeth. It is pathology with variable severity; it can partially or totally cover the dental crowns, generating an aesthetic prejudice and numerous functional problems such as malocclusions, difficulties in mastication and traumatic ulcerations. It can be isolated (autosomal dominant transmission) or associated with several individualized syndromes to which are added numerous extra-oral signs (mental retardation, hypertrichosis, hepatosplenomegaly, epilepsy...). The dental surgeon plays a key role in its diagnosis and management. The treatment of this disorder is mainly surgical. This work aims to describe this little known pathology and its management through the illustration of a case managed at the University Hospital of Sidi bel Abbes..

Key words: gingival fibromatosis, genetic pathology, aesthetic and functional damage, surgery

[1]. Almiñana-Pastor.PJ , Buitrago-Vera.PJ ,Alpiste-Illueca .FM , Pizarro.MC . Hereditary gingival fibromatosis: Characteristics and treatment approach. J Clin Exp Dent. 2017;9(4):e599-602. PubMed
[2]. Gawron K, Bereta G, Nowakowska Z, Łazarz-Bartyzel K, Potempa J, Chomyszyn-Gajewska M, et al. Analysis of mutations in the SOS-1 gene in two Polish families with hereditary gingival fibromatosis. Oral Dis. 2017;23(7):983-9. PubMed
[3]. Fang L, Wang Y, Chen X. Gene expression profiling and bioinformatics analysis of hereditary gingival fibromatosis. Biomed Rep. 2018;8(2):133-7. PubMed
[4]. Yadav VS, Chakraborty S, Tewari S, Sharma RK. An unusual case of idiopathic gingival fibromatosis. Contemp Clin Dent. 2013;4(1):102-4. PubMed
[5]. Dani NH, Khanna DP, Bhatt VH, Joshi CP. Idiopathic gingival fibromatosis. J Indian Soc Periodontol. 2015;19(6):698-700. PubMed

Abstract: India alone accounts for one-fourth of global burden of cervical cancers. It is the commonest malignancy in female population in rural India.Usually it present in a locally advanced stage[1].Chemoradiotherapy usually the treatment of choice for locally advanced stage[1,2].The main aim of this study is to find out the prognostic factors which are most important for treatment outcome & survival.It is a retrospective study done in the department of Radiotherapy in a rural based medical college of west Bengal (Bankura sammilani medical college & Hospital Bankura) from september 2008 to august2013. A total of three hundred fifty six patients were included in this retrospective study. Patients were treated with Radical radiotherapy with concomitant cisplatin...

Keywords: cancer cervix,radiotherapy, chemotherapy, prognostic factor,survival

[1]. Whitney CW, Sause W, Bundy BN, Malfetano JH. Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic
Oncology Group and Southwest Oncology Group study. J Clin Oncol. 1999 May;17(5):1339-48
[2]. Eifel PJ, Winter K, Morris M. Pelvic irradiation with concurrent chemotherapy versus pelvic and para-aortic irradiation for high risk cervical cancer: an update of radiation therapy oncology group trial (RTOG) 90-01. J Clin Oncol. 2004 Mar 1;22(5):872-80
[3]. Rose PG, Ali S, Watkins E, Thigpen JT, Deppe G; Long-term follow-up of a randomized trial comparing concurrent single agent cisplatin, cisplatin-based combination chemotherapy, or hydroxyurea during pelvic irradiation for locally advanced cervical cancer: a Gynecologic Oncology Group Study. J Clin Oncol. 2007 Jul 1;25(19):2804-10
[4]. Keys HM, Bundy BN, Stehman FB, Okagaki T, Gallup DG; Radiation therapy with and without extrafascial hysterectomy for bulky stage IB cervical carcinoma: a randomized trial of the Gynecologic Oncology Group. Gynecol Oncol. 2003 Jun;89(3):343-53
[5]. Nandakumar A, Anantha N, Venugopal TC. Incidence, mortality and survival in cancer of the cervix in Bangalore, India. . Br J Cancer. 1995 Jun;71(6):1348-52

Abstract: On March 11, 2020 World Health Organization (WHO) declared corona virus disease (COVID-19) a public health emergency of international concern since its outbreak in Wuhan, China.1Coronaviruses are enveloped RNA viruses that are distributed widely among humans, other mammals and birds and they cause respiratory, neurologic, hepatic and enteric diseases.2,3 Six coronavirus species are known to cause human disease and four of them - 229E, OC43, NL63, and HKU1 are less pathogenic causing common cold symptoms in immunocompetent individuals.4The two other strains - severe acute respiratory syndrome coronavirus (SARS CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) - are zoonotic in origin and sometimes causes fatal illness.5 Towards the end of 2019, a novel mutation of coronavirus (labelled as SARS-CoV2) was identified as the cause of a severe respiratory.........

[1]. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. China novel coronavirus investigating and research team. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727-33.
[2]. Weiss SR, Leibowitz JL. Coronavirus pathogenesis. Adv Virus Res. 2011;81:85-164.
[3]. Masters PS, Perlman S. Coronaviridae. In: Knipe DM, Howley PM, eds. Fields virology. 6th ed. Lippincott Williams and Wilkins; 2013:825-858.
[4]. Su S, Wong G, Shi W, Liu J, Lai AC, Zhou J, et al. Epidemiology, genetic recombination, and pathogenesis of coronaviruses. Trends Microbiol. 2016;24:490-502.
[5]. Cui J, Li F, Shi ZL. Origin and evolution of pathogenic coronaviruses. Nat Rev Microbiol. 2019;17:181-92.

Abstract: Objective: A regular collection of cytology specimens from bronchoalveolar washing is expected to increase the ability of bronchoscopy to diagnose lung cancer. However, we aimed to study the sensitivity of cytology washing tests for diagnosing malignant lung lesions. Methods: This is a retrospective study including 68 patients who underwent different thoracic surgeries for lung cancer in St. Vincent University Hospital from June 2013 to March 2020. The results of all cytology specimens from bronchoalveolar washing were reviewed from the patients' files.....

Key Words: cytology, lung cancer, sensitivity

[1]. Patrick James Villeneuve. Interventions to avoid pulmonary complications after lung cancer resection . J Thorac Dis. 2018 Nov; 10(Suppl 32): S3781–S3788.
[2]. Bo Cheng, Shan Xiong . An annual review of the remarkable advances in lung cancer clinical research in 2019.J Thorac Dis. 2020 Mar; 12(3): 1056–1069.
[3]. William D Travis. Lung Cancer Pathology: Current Concepts. Clin Chest Med. 2020 Mar;41(1):67-85.
[4]. John R Handy Jr, Michael Skokan. Results of Lung Cancer Screening in the Community. Ann Fam Med. 2020 May;18(3):243-249.
[5]. Gerard A Silvestri, Benjamin T Bevill. An Evaluation of Diagnostic Yield From Bronchoscopy: The Impact of Clinical/Radiographic Factors, Procedure Type, and Degree of Suspicion for Cancer. Chest. 2020 Jun;157(6):1656-1664

Abstract: Background : Soft tissue tumours (STTs) have various presentations depending on their tumor site and size; they may be accompanied by swelling, pain, tenderness, or motion impairment and are classified by their origin as muscular, fatty, fibrous, neural, vascular, or synovial. STTs frequently occur in the limbs, and the thigh is the most commonly affected site. However the characterization of musculoskeletal soft tissue lesions is challenging as most malignant, benign and non-neoplastic soft tissue lesions following trauma or inflammation have similar presentations. Magnetic resonance imaging (MRI) can be used to accurately detect the anatomical extent of musculoskeletal Soft tissue tumours . The technique is important in STT......

[1]. Miwa S, Otsuka T. Practical use of imaging technique for management of bone and soft tissue tumors. J Orthop Sci 2017;22:391–400.
[2]. Ramu EM, Houdek MT, Isaac CE, Dickie CI, Ferguson PC, Wunder JS. Management of soft-tissue sarcomas; treatment strategies, staging, and outcomes. SICOT J 2017:3–20.
[3]. Van Rijswijk CS, Kunz P, Hogendoorn PC, et al. Diffusion-weighted MRI in the characterization of soft tissue tumors. J Mag Res Imaging 2002;15(3):302–7.
[4]. Ahlawat SH, Fayad LM. De novo assessment of pediatric musculoskeletal soft tissue tumors: beyond anatomic imaging. Pediatrics 2015;136(1):194–201.
[5]. Szafer A, Zhong J, Gore JC. Theoretical model for water diffusion in tissues. Magn Reson Med. 1995; 33:697–712. https://doi.org/10.1002/mrm.1910330516 pmid:7596275..

Abstract: Background: This was a study conducted to assess the contraception awareness among women with unplanned pregnancies and their outcomes, during lockdown period of COVID-19 pandemic. Materials and Methods: We conducted an observational study on 50 cases of unplanned pregnancies during the lockdown period from 25 March 2020 till 31 July 2020. Women were assessed based on their basic information and knowledge of contraception. Maternal outcomes were assessed based on the period of gestation, mode of abortion and choices of future contraceptives. Results: Incidence of unplanned....

Keywords: unplanned pregnancy, COVID-19, contraception

[1]. V Chandrashekar, Ankur Sagar. Impact of COVID 19 on India's Family Planning Program. Foundation for Reproductive Health Services India Policy Brief May 2020.
[2]. Susheela S, Rubina H, Chander S, Rajib A, Ann M M, Melissa S et al. Abortion and Unintended Pregnancy in Six Indian States: Findings and Implications for Policies and Programs, New York: Guttmacher Institute, 2018.
[3]. Kaye W, Kyle GJ, Catherine HM, Clare T, Soazig C, Jessica D et al. The prevalence of unplanned pregnancy and associated factors in Britain: findings from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). Lancet.2013 Nov; 382(9907): 1807-1816.
[4]. Habib MA, Camille RG, Nausheen S, Soofi SB, Sajid M, Bhutta ZA et al. Prevalence and determinants of unintended pregnancies amongst women attending antenatal clinics in Pakistan. BMC Pregnancy and Childbirth. 2017; 17:156.
[5]. Edward K A, Eugene B, Francis S, Linus B, Francis A, Abdul A S et al. Prevalence and determinant of unintended pregnancy in sub-Saharan Africa: A multi-country analysis of demographic and health surveys. PLOS ONE. 2019 Aug; 14(8): e0220970..

Abstract: Background :This study is on the effect of aqueous extract of Abelmoschusesculentus on the epididymis of male adult Wister rats on the body weight. Materials and Methods :Twenty one adult male wistar rats weighing 100-120g were assigned into three groups (A, B and C). Group A for control received standard grower feed and water, Group B for low dose received food, water and aqueous of Abelmoschusesculentus at a dose of 1.0mg/KgBw and Group C for high dose received food, water and aqueous extract of Abelmoschusesculentus at a dose of 3.0mg/kgBw. Administration was done orally for two weeks. At the end of the administration, the body weight was recorded using sensitive weighing balance and the animals were sacrificed using cervical dislocation and the epididymis was harvested and preserved in 10% buffered formalin (NBF) followed by H&E staining. Result shows an observable.....

Keywords: Epididymis, Abelmoschusesculentus, wistar rats, tubule, tissue, weight

[1]. Kumar, D.S., D.E. Tony., Kumar A. P.,Kumar K. A, Rao D. B. S and Nadendla R., (2013). A review on: Abelmoschusesculentus (okra). International Research Journal of Pharmaceutical and Applied Sciences, 3(4): 129-132.
[2]. Lengsfield C, Tigemeyer F., Faller G., Hensel A. (2014). Glycosylated compounds from okra inhibits adhesion from Helicobacter pylori to human gastric mucosa. Journal of Agricultural and Food Chemistry. 5 2(6): 1495-1503
[3]. Gemede H., Ratta N., Haki G.D., WoldegiorgisAshagrie Z.B.F.( 2014). Nutritional Quality and Health Benefits of Okra (Abelmoshusesculentus): A review, International Journal of Nutritional and Food Science. 4(2): 2008-215
[4]. Mehran D., Seyyed M. S., Ayoob J (2013). Effects of Fumariaparviflora leaves extract on reproductive parameters in adult male rats. Iran J Reprod Med Vol. 11. No. 11. pp: 891-898
[5]. Mairuae N, cheepsunthorn CL, Tongjaroenbuangam W. (2015). Okra (Abelmoschusesculentus Linn) on cellular events associated with Alzhiemer's disease in a stably expressed HFE neuroblastoma SH-SY5Y cell line. Neuroscience Letters.603:6-11

Abstract: Bisphosphonates are widely used in medical practice. Osteonecrosis of the jaw (ONJ) was first reported in the dental literature in 2003. Eighteen years later, this pathology is still topical and increasingly publicized, particularly because of its disabling clinical consequences and the complexity of treatment. The objective of this work is to focus on this pathology which is disabling , very difficult to treat and to show that preventive treatment based on patient information in relation to the risks of this therapy ,the restoration of the oral cavity before the introduction of bisphosphonate treatment and the eviction of avulsions except in extreme cases of mobility remains the only way to avoid this complication.

Keywords: osteonecrosis, Bisphosphonates, metastatic breast cancer

[1]. Marx RE. 2003 .Pamidronate (Arédia) and zoledronate (Zométa) induced avascular necrosis of the jaws: a growing epidemic. J Oral Maxillo.fac.Surg. PubMed.
[2]. Ruggiero.SL, Marx.RE, Mehrotra.2009.American Association of Oral and maxillofacial Surgeons (AAOMS) position paper on bisphosphonate- related ostéonécrosis of the jaw; update. J Oral Maxillo facial Surgery . PubMed.
[3]. Stockmann. P. 2010.Panoramic radiograph, computed tomography or magnetic resonance imaging. which imaging technique should be preferred in bisphosphonate-associated osteonecrosis of the jaw? a prospective clinical study clin oral invest, 14 : 311–317.
[4]. Hutchinson. M et al .2010.Radiographic Findings in Bisphosphonate- Treated Patients With Stage 0 Disease in the Absence of Bone Exposure J Oral Maxillofac Surg, 68 : 2232-2240
[5]. Treister, n. woo,s et al.2009. Dental panoramic radiographic evaluation in bisphosphonate-associated osteonecrosis of the jaws oral diseases, 15 : 88–92.

Abstract: Most common genitourinary malignancy in men & the third most common known cause of death in men – "Prostate cancer" (1). The multiparametric (Mp-MRI) approach using 3 different techniques, T2-weighted (T2W) MRI, diffusion-weighted imaging (DWI), and dynamic contrast-enhanced MRI (DCE-MRI) improve the diagnostic accuracy (3). Prostate Imaging Reporting and Data System (PI-RADS) has been purposed by European Society of Urogenital Radiology (ESUR) , the body has called a panel of experts in February 2012 and published a guideline providing recommendations for the performance of mp-MRI investigations......

[1]. Dickinson L, Ahmed HU, Allen C, et al. Magnetic resonance imaging for the detection, localization, and characterization of prostate cancer: recommendations from a European consensus meeting. Eur Urol 2011;59:477–94.
[2]. Daniel J, Georg S, Michael E, et al. Evaluation of the PI-RADS Scoring System for classifying mpMRI findings in men with suspicion of prostate cancer. BioMed Res Int 2013:9 252939.
[3]. Barentsz JO, Richenberg J, Clements R, et al. ESUR prostate MR guidelines 2012. Eur Radiol 2012;22:746–57.
[4]. Joyce GR, Jelle OB. Standardization of multiparametric prostate MR imaging using PI-RADS (Review Article). BioMed Res Int Vol 2014:9 431680.
[5]. Hamoen EH, de Rooij M, Witjes JA, et al. Use of the prostate imaging reporting and data system (PI-RADS) for prostate cancer detection with multiparametric magnetic resonance imag- ing: a diagnostic meta-analysis. Euro Urol 2015;67:1112–21.