iosr-JDMS   Volume-20 ~ Issue-11 ~ November 2021

Abstract: Rationale: Dengue is an arthropod-borne viral infection transmitted to humans through bites of infected female Aedes mosquitoes. Pulmonary manifestations are rare can present as pleural effusion, pneumonia, non-cardiogenic pulmonary edema, acute respiratory distress syndrome which coincides with decreased platelet count and capillary leakage. Patient concern: pleural effusion, pneumonia, pneumothorax
Intervention: fluids, antibiotics, analgesics and antipyretics, intercostal drainagetube. Conclusion: Pulmonary manifestations in dengue fever are rare. Dengue fever can be considered as a differential diagnosis in patients with pleural effusion and pulmonary infiltrates if recognized early and intervened to prevent mortality..

Key Word: Dengue,Pleuraleffusion,Pneumonia

[1]. Edson Marchiori, Bruno Hochhegger, Glaucia Zanetti. Pulmonarymanifestations of dengue. J Bras Pneumol. 2020;46(1): e20190246
[2]. SiripenKalyanarooj. Clinical Manifestations and Management of Dengue/DHF/DSS. Tropical Medicine and Health. 2011;39(4): 83-87 3. Swapndeep Singh Atwal, SwapnilPuranik, ShibaniMehra, Umesh Chandra Garga. Pneumocystis Pneumonia-A Novel Complication in a Non-HIV Dengue Patient. Journal of Clinical and Diagnostic Research. 2014;8(9): 01-02 4.Rosana Souza Rodrigues, Ana Livia Garcia Brum, Marciano Viana Paes, etal.
[3]. Lung in Dengue: Computed Tomography Findings. PLOS ONE. 2014;9(5): e96313 5.Gathsaurie NeelikaMalavige, Graham S. Ogg. Pathogenesis of vascular leak in dengue virus infection. Immunology. 2017;151: 261-269
[4]. VirojWiwanitkit. Dengue Pneumonia: A Tropical Problem. InternationalJournal of Pulmonology and Infectious Diseases.2018
[5]. Dengue fever-symptoms, treatment, prevention.southern cross.co.nz.Last Reviewed-March2020

Abstract: Background: Regulatory T cells play a critical role in maintenance immunological tolerance while preserving tumour and microbial immunity. Several clinical trials have found that Tregs can treat and prevent graft versus host disease (GVHD, without increasing the risk of relapse and infection. Tregs are identified by co-expression of CD4, high expression of CD25 and Foxp3. Foxp3is specifically expressed in Tregs and is important to control their stability and development. . Materials and Methods: In this study, 20 consecutive s allogeneic hematopoietic stem cell transplantation (HSCT) recipients during the first year post transplantation were analysed by measuring the percentages of regulatory T cells every month for each patient. Data were presented as minimum, maximum and mean.......

Key words: Allogeneic Hematopoietic stem cell transplantation, Regulatory T cells, Reconstitution, graft versus host disease, Recovery

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[5]. Feuerer M, Hill JA, Mathis D, et al. Foxp3+ regulatory T cells: differentiation, specification, sub phenotypes. Nat .Immunol. 2009; 10(7): 689-695.

Abstract: Carcinoma cervix is one of the leading causes of death of the female population in developing countries. PAP test or PAP Smear is a screening test widely used to identify potentially pre-cancerous & cancerous lesion of the cervix. It was invented by Georgios Papanikolaou in 1920 and introduced in cervical cytological screening in 1940. Cervical lesions if treated in earlier stages, the patient can be cured of the disease because cervical cancer has very long pre-invasive stage. PAP test represents the most effective technique to prevent and detect the precancerous conditions of the uterine cervix before they becomes invasive cancer, its false negative yield due to the potential sampling and interpretation errors yield is still a reason of concern. In this paper we evaluate the pattern of cervical....

Keywords: Pap smear, Cytology, Histopathology & Cervix biopsy

[1]. Das D, Kar A, Rath S, Baliarsingh SK, Prusty D, Dash AK. Cytological pattern of papanicolaou smears and detection of cervical cancers: An experience from a tertiary care center of eastern zone of India. Oncol J India. 2018;2(2):25. 12.
[2]. Narayana G, Suchitra MJ, Sunanda G, Ramaiah JD, Kumar BP, Veerabhadrappa KV. Knowledge, attitude, and practice toward cervical cancer among women attending obstetrics and gynecology department: a cross-sectional, hospital-based survey in South India. Indian J Cancer. 2017;54(2):481. 13.
[3]. Arya R, Arora R, Benwal D, Kumar VK, Verma S. Can visual inspection after acetic acid replace papanicolaou smear. J Evidence-Based Women's Health J Soci. 2015;5(1):38.
[4]. Garg R, Desai R. Cytologic and colposcopic evaluation of all symptomatic women at tertiary care centre. Int J Adv Med. 2017;4:799-80.
[5]. Sinha S, Singh V, Mishra B, Singh A. Comparing the efficacy of visual inspection of cervix with acetic acid and Lugol's iodine with Pap smear cytology in screening for cancer cervix. J Cur Res Scient Med. 2018;4(1):10.

Abstract: Background :Hereditary palmoplantar keratodermas (HPPKD) are a heterogenous group of keratinizing disorders classified based upon their mode of inheritance, age of onset, morphology and distribution of palmoplantar thickening.Clinically classified into four major types :1.Diffuse2.Focal3.Striate and 4.Punctate.They are more prone for secondary infections like tinea pedis, tinea manuum, pitted keratolysis and maceration of skin.As they are rare disorders, literature reports are based on individual family reports.Only few studies are available about the prevalence of palmoplantar keratoderma in the Indian population till date. Aim : To study the clinical and epidemiological trend of hereditary palmoplantar keratoderma. Objective : To analyze the age and sex........

Keywords: Hereditary, Palmoplantar keratoderma , Inherited , Genodermatoses, Syndrome

[1]. R. Judge, W.H.I.Clean, C.S.Munro, Disorders of Keratinization. Rooks Text Book of Dermatology 9th Edition Volume 2 chapter 65 pg 1736.
[2]. David .P Kelsell, Lrene M. Leigh, Inherited Keratoderma of Palms andSoles. Fitzpatricks Dermatology in general medicine 9th edition. volume 1 chapter 48 pg 817.
[3]. Alfrons L KrolKeratodermas,. Dermatology 4th edition by Jean L Bolognia,Joseph L Jorizzo, Ronald P Rapini section 9 chapter 58 pg 924 .
[4]. Schiller S, Seebode C, Hennies HC, Giehl K, Emmert S. Palmoplantar keratoderma (PPK): acquired and genetic causes of a not so rare disease. J Dtsch Dermatol Ges 2014; 12: 781–788.
[5]. Duchatelet S, Hovnanian A. Olmsted syndrome: clinical,molecular and therapeutic aspects. Orphanet J Rare Dis 2015; 10: 33.

Abstract: Background and aims: Covid-19 pandemic and lockdown has brought about a sense of fear and anxiety around the globe. This phenomenon has led to short-term and long-term psychosocial, mental, and physical health implications for children, adolescence, and adults. This study was planned to see the various psychosocial and behavioral effects like sleep patterns, eating habits, extracurricular activities, school closure, electronic gadgets, and internet usage, etc. in children during the lockdown.......

Keywords: Lockdown, Psychosocial and behavioral aspects, Children

[1]. Singh, S., Roy, D., Sinha, K., Parveen, S., Sharma, G., & Joshi, G. (2020). Impact of covid 19 and lockdown on mental health of children and adolescents: A narrative review with recommendations. Psychiatry research vol. 293(2020):113429.
[2]. UNICEF 2021: Covid 19 and children- UNICEF data. http://data.unicef.org/covid-19-and-children/
[3]. Lee J. Mental health effects of school closures during COVID-19. The Lancet Child & Adolescent Health. 2020 Jun 1;4(6):421.
[4]. Viner RM, Russell SJ, Croker H, Packer J, Ward J, Stansfield C, Mytton O, Bonell C, Booy R. School closure and management practices during coronavirus outbreaks including COVID-19: a rapid systematic review. The Lancet Child & Adolescent Health. 2020 May 1;4(5):397-404.
[5]. Kaditis AG, Ohler A, Gileles‐Hillel A, Choshen‐Hillel S, Gozal D, Bruni O, Aydinoz S, Cortese R, Kheirandish‐Gozal L. Effects of COVID-19 lockdown on sleep duration in children and adolescents:A survey across different continents. Pediatric pulmonology.2021 Apr 22..