iosr-JDMS   Volume-16 ~ Issue-7 ~ July-2017

Abstract: Raine syndrome, also known as lethal osteosclerotic bone dysplasia, is a rare genetic disorder with characteristic features of exophthalmos, microcephaly, depressed nasal bridge, bilateralchoanal atresia, gum hyperplasia, osteosclerosis& cerebral calcification.Most of babies with this disorder die immediately after birth. We report a case of baby who is 2 days old at the time of presentation.

Keywords: Raine Hereditary Osteosclerosis Microcephaly

[1]. Raine j, winter rm, daveya, tucker sm, unknown syndrome- microcephaly, hypoplastic nose, exophthalmos, gum hyperplasia, cleft palate, low set ears, osteosclerosis. J med genet 1989:26:786-788
[2]. Simpson ma, sheruerle a, hurst j, patton ma, stewart h, crosby ah, mutation in fasm20c also identified in non lethal osteosclerotic bone dysplasia. Clin genet 2009:75:271-276
[3]. Kan ae, kozlowski k. New distinct lethal osteosclrotic bone dysplasia.(raine syndrome). Am j med genet 1992;43:860-864 Al-mane k, al-dayel f, mcdonald p. Intracranial calcification in raine syndrome: radiologial pathological correlation. Paediatric radiol 1998;28:820-823
[4]. Ohlsson a, cumming wa, paul a, sly ws. Carbonic anhydrase ii deficiency, recessive syndrome with renal tubular acidosis & intracranial calcification. Paediatric . 1986;77:371-81

Abstract: The authors describe a case of osteosarcoma in a 9 years old male who presented with complaints of pain and swelling in Left leg in the OPD facility of RIMS, Ranchi, Jharkhand. Osteosarcoma is the most common malignancy in childhood and adolescence. However, it is very rare in children under 5 years of age. Although studies in young children are limited in number, they all underline high rate of amputation in this population, with conflicting results being recently reported regarding their progress.

Keywords : Osteosarcoma,Young children.

[1]. Rosenberg AE. Robins and cotran pathologic basis of disease. 8th ed. Philadelphia: WB Saunders; 2010. Bone, joints and soft tissue tumors; pp. 1203–56.

[2]. Fletcher CDM, Bridge JA, Hogendoorn PCW, Mertens F, editors. Lyon: IARC Press; 2013. World Health Organization, classification of tumours: Pathology and genetics of tumors of soft tissue and bone.

[3]. Wold LE, Adler CP, Sim FH, Unni KK. 2nd ed. Philadelphia-London: Saunders; 2003. Atlas of orthopaedic pathology; pp. 179–85.

[4]. Jaffe HL. Philadelphia: Lea and Febiger; 1958. Tumors and tumors like conditions of the bones and joints.

[5]. Unni KK. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2010. Inwards CY Bone tumors: General aspects and data on 10,165 cases.

Abstract: The pathogenesis of 'abfraction' has been considered to be multifactorial with contributions from occlusal loading becoming increasingly prominent in recent years. The objective of this study was to find out whether the presence of an extensive occlusal amalgam restoration and eccentric parafunctional loads would cause increased cuspal movement and therefore, increase in cervical stress exceeding the failure stress of enamel, capable of initiating tooth substance loss...........

Keywords: Abfraction, occlusal restoration, cuspal flexure, bruxism finite element study.

[1]. Levitch LC, Bader JD, Shugars DA and Heymann HO. Non- carious cervical lesions. J. Dent. 1994; 22: 195-207.
[2]. Grippo J.O. Bioengineering seeds of contemplation: a private practitioner‟s perspective. Dent Mater 1996; 12:198-202.
[3]. Lee WC and Eakle WS. Possible role of tensile stresses in the etiology of cervical erosive lesions of teeth. J. Prosthet. Dent. 1984; 52:374-380.
[4]. Grippo JO. Abfractions: A new classification of hard tissue lesions of teeth. J. Esthet.Dent.1991; 3:14-19.
[5]. Xhonga FA. Bruxism and its effect on the teeth. J. Oral Rehabil 1977; 4: 65-76

Abstract: Background: The aim of present study was to evaluate the effect of 6 minute walk test in patients suffering with COPD. The study was conducted in 120 male and female subjects between 40- 80 years of age (30 subjects were taken as control and 90 subjects were patients suffering from COPD). Then COPD subjects were further sub-divided on basis of Gold classification (3).Subjects taking current chronic treatment with steroids or history of cystic fibrosis or any respiratory tract infection were excluded from study. Material and method: A structured proforma was given to subject to elicit lifestyle and systemic diseases. Then assessment of anthropometric parameters, cardiovascular parameters and exercise capacity by 6 minute walk test was done as per ATS guidelines 2002 (1). VO2 max was calculated and was compared with normal values (2). Dyspnea and fatigue levels were assessed using Borg dyspneic scale.............

Keywords: Six minute walk test (6MWT), chronic obstructive pulmonary disease (COPD), Borg dyspneic scale

[1]. ATS statement: Guidelines for six minute walk test. Am. J. Resp. Crit. care Med 2002. Jul 1; 166 (1): 111-7
[2]. V. H. Heyward. Advanced fitness assessment and exercise prescription. Fitness/ exercise article/VO2 and VO2 max.
[3]. Rosalie J et al. The clinical utility of GOLD classification of COPD disease severity in pulmonary rehabilitation. Respiratory medicine vol. 102, 2008, Jan 1, 62-171.
[4]. P.J.Barnes COPD cellular and molecular Mechanism VOL 19
[5]. Menezes AM. Chronic obstructive pulmonary disease in five Latin American cities (the PLATINO study): a prevalence study 2005 Nov 26;366(9500):1875-

Abstract: Trauma victims occupy 10-38% of hospital beds in the country as reported by WHO SEARD, Jan., 2001. The burden of road traffic injury alone amount to Rs 55000 crores (3% of GDP) in direct and indirect socio- conomic losses as reported by India Injury Report (2005) 1. Head injury continues to be a nightmare not only for public but also for the neurosurgeon, because of high morbidity and mortality. There has been no change in mortality and morbidity of severe head injury in last 30 years2. Though spontaneous intracranial haemorrhage in uncommon in children , it is an important cause of death and permanent neurological deficit in children. Common causes for spontaneous intracranial haemorrhage include congenital vascular anomalies of brain, brain tumour and congenital heart disease

[1]. 1 Mahapatra AK: A textbook of head injury. Modern Publishers, 3rd Edition, 2005, pg. 1.
[2]. Holland D, Shigaki CL. Educating families and caretakers of traumatically brain injured patients in the new health care
environment: a three phase model and bibliography. Brain Injury 12(12): 993-1009, 1998.
[3]. Junque C, Bruna O, Mataro M. Information needs of the traumatic brain injury patient's family members regarding the
consequences of the injury and the associated perception of physical, cognitive, emotional and quality of life changes. Brain Injury
11(4): 251-258, 1997.
[4]. NIH Consensus development panel on rehabilitation of persons with traumatic brain injury. Rehabilitation of persons with traumatic
brain injury. 282: 974-983, 1999.
[5]. Friedman GF, Suzbon L et al. Apolipoprotein E epsilon 4 genotype predict poor outcome in survivors and traumatic brain injury.
Neurology 15: 244-248, 1999.

Abstract: Successful placement of dental implant is a challenge in posterior edentulous maxilla, where the alveolar bone is lost due to extensive resorption, and the pneumatisation of maxillary sinus and spongy nature of bone. This study compare the merits and demerits of a new technique of crestal condensation - Minimally Invasive Crestal Condensation (MICC) with conventional lateral window approach. In this study we found the following advantages for this new technique which appears promising for doing routine sinus lift ............

Keywords:Dental Implants, minimally invasive, Immediate Implants, crestalcondensation

[1]. Sunitha V. Raja. Management of the Posterior Maxilla with Sinus Lift: Review of techniques. Oral and Maxillo Facial Surgery 67:1730-1734, 2009. [2]. Summers RB. A new concept in maxillary implant surgery: the osteotome technique. Compendium. 15(2):152, 154-6, 1994 Feb;

[3]. MetodiAbadzhiev:Alternative sinus lifts techniques literaturereview: Journal of International Medical Association of Bulgaria Annual Proceeding: 2009.
[4]. M.Esposito, M.G.Grusovin, J.Rees et al., ―Effectiveness of sinus lift procedures for dental implant rehabilitation: a Cochrane systematic review,‖ European journal of oral implantology. 3: 7–26. 2010;
[5]. M.DelFabbro, G.Rosano,andS.Taschieri, ―Implant survival rates after maxillary sinus augmentation,‖ European Journal of Oral Sciences.116: 497–506. 2008;

Abstract: The development of aesthetic and adhesive dentistry and the availability of reliable new dental materials have changed the daily practice of dentistry because these advances have led to more conservative cavity design and preservation of maximum sound dental tissues. The objective of this study is to compare the bond strength and microleakage of Compomer with Composite and Glass ionomer (conventional and light cured); and also to study the tooth-restorative interface using SEM Materials and Method: 88 human premolar teeth extracted for orthodontic purposes were selected for this study, specimens were subjected to shearing stress in the Intron universal Testing machine & autoradiographs...........

Keywords: Compomer, Glass Ionomer, Composite Resins, Bond Strength, Microleakage

[1]. James . S . Reid , William. P. Saunders, Scott. W. Sharkey, Catherine.E.C.S. Williams: An invitro investigation of microleakage and gap size of Glass ionomer/composite resin "sandwich" restorations in primary teeth: J Dent Child, 255-259: 1994.
[2]. Stephen. C . Bayne, Herald.O.Heymann, Edward.J, Swift JR: Update on dental composite restorations: JADA, Vol. 125, 687-701: 1994.
[3]. A.B. Wilson, B.E. Kent: A new translucent cement for dentistry-The glass ionomer cement: BDJ, 132, 133-135: 1972.
[4]. Kidd.E.A.M: Cavity sealing ability of composite and glass ionomer cement restorations: BDJ, 144, 139-142: 1978.
[5]. Maldonado.A, Swartz.M.L, Phillips.R.W: An in vitro study of certain properties of a glass ionomer cement: JADA, 96, 785-791:1978.

Abstract: Introduction: Spinal anesthesia is the most preferred regional anaesthesia technique as it is easy to perform, economical and produces rapid onset of anaesthesia and complete muscle relaxation. The aim of intrathecal local anesthetic is to provide adequate sensory and motor block necessary for all lower abdominal and lower limb surgeries. The sole essence of anaesthesia is relief of pain in intra and post-operative period. Over the last decade, there has been considerable revival of interest in the use of adjuncts to local anaesthetic agents in central neuraxial blockswith the aim of prolonging the duration of sensory and motor block and reducing post-operative analgesic requirements...........

Keywords: Transdermal nitroglycernine patch, Clonidine, Bupivacaine, spinal anaesthesia, lower abdominal surgeries.

[1]. Ellish H, Feldman S and Griffiths OHW, editors. The vertebral canal and its contents. In: Anatomy for Anaesthetists. 8th ed .Oxford: Blackwell Publishing; 2004.p.95-135.
[2]. Kleinman W. Spinal, epidural and caudal blocks. In: Morgan EG, Mikhail SM and Murray JM Editors. Clinical anesthesiology. 3rd ed. New Delhi: Lange Medical Books, McGraw Hill Medical Publishing Division; 2002.p.253-82.
[3]. Brown LD. Spinal, epidural and caudal anesthesia. In: Miller DR Editor. Miller's Anesthesia. 6th ed. Philadelphia: Elsevier Churchill Livingstone; 2005.p.1653-83.
[4]. Chaurasia BD, editor. Bones and joints of thorax. In: Human anatomy, Regional and clinical applied dissection. 4th ed. New Delhi: CBS Publishers and Distributors;2004.p. 189-204.
[5]. International Association for the Study of Pain. Pain 1979;6:249-252.

Abstract: Diabetic foot is a leading cause of DALY with both physical and economic cost to the patient. With increasing cost of healthcare and antibiotic resistance, there is a need for new and innovative methods for management of the diabetic foot ulcers. Ourresearch studied the effect of local application of probiotics on the healing of diabetic foot ulcers by comparing the changes in wound bed score and wound swab culture results in the test and control population. The control group was managed by the current regimen of sharp and chemical debridement at ward, cleaning and dressing, glycemic management and antibiotic therapy...........

Keywords: Probiotics, diabetic foot ulcer, lactobacillus, gangrene

[1]. Wild S, Roglic G, Green A, et al. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 2004;27:1047-53.
[2]. Singh N, Armstrong DG, Lipsky BA. Preventing foot ulcers in patients with diabetes. JAMA 2005;293:217-28.
[3]. Prompers L, Huijberts M, Apelqvist J, et al. Optimal organization of health care in diabetic foot disease: introduction to the Eurodiale study. Int J Low Extrem Wounds 2007;6:11-7.
[4]. Jeffcoate WJ, Harding KG. Diabetic foot ulcers. Lancet 2003;361:1545-51.
[5]. Boulton AJ, Meneses P, Ennis WJ. Diabetic foot ulcers: A framework for prevention and care. Wound Repair Regen 1999;7:7-16.

Abstract: Introduction: Urinary tract infection (UTI) is one of the common hospital-acquired infections and there is increasing interest developing in this area because of external forces, such as mandatory public reporting of nosocomial infections and "zero tolerance" to hospital-acquired infections. Most of the literature concerning the use of antimicrobial catheters for prevention of CAUTI is limited by improper study methods or by a failure to understand the difference between CAUTI and ASB.In our institution we investigated the possibility of reducing CAUTI by instillation of povidone iodine in to the bladder before routine catheter change in long term catheterized patients.............

Keywords: CAUTI, Catheter Associated Urinary Tract Infections,Povidone Iodine

[1]. Weinstein JW, Mazon D, Pantelick E, et al. A decade of prevalence surveys in a tertiary-care center: trends in nosocomial infection rates, device utilization, and patient acuity. Infect Control Hosp Epidemiol.1999 Aug;20(8):543–8. [PubMed]

[2]. Richards M, Edwards J, Culver D, Gaynes R. Nosocomial infections in combined medical-surgical intensive care units in the United States. Infect Control Hosp Epidemiol. 2000;21:510–5. [PubMed]

[3]. Saint S, Kowalski CP, Kaufman SR, et al. Preventing hospital-acquired urinary tract infection in the United States: a national study. Clin Infect Dis. 2008 Jan 15;46(2):243–50. This survey of infection control coordinators at 119 Veterans Affairs and 600 non-federal US hospitals gives a snapshot view of what hospitals were or were not doing in 2005to prevent hospital-acquired UTI. [PubMed]

[4]. Brown J, Doloresco F, III, Mylotte JM. "Never events": not every hospital-acquired infection is preventable. Clin Infect Dis. 2009 Sep 1;49(5):743–6. The authors provide a cogent critique of the Medicare reimbursement changes. [PubMed]

Abstract: Background:.Synechiae is rarely seen as an isolated disease. It is generally observed together with various syndromes such as Van der Woude and cleft palate lateral alveolar synechiae syndrome, and is concomitant with other anomalies in the maxillofacial or other regions of the body. Case:This article reports a case of isolated congenital alveolar synechiae in a 3 year old baby girl. Release of the synechia was performed without complications. We review the current literature and discuss diagnosis and surgical management of this rare condition.

Keywords: Adhesion,Cleft palate, Congenital, Floor of the Mouth, Synechia,Syngantia,

[1]. Michael German, M.D., Hausin Wong, M.D. Oral Synechia With Epithelial Cyst in Neonate With Cleft Palate:A Case Report Cleft Palate–Craniofacial Journal, May 2011, Vol. 48 No. 3
[2]. R. Tanrikulu1, B. Erol2, B. Görgün and ÖIlhan Congenital alveolar synechiae —a case report BRITISH Dental Journal Volume 198 NO. 2 January 22 2005
[3]. Omer Salahuddin, KanwalYousaf, Mamoon Rashid, ShumailaYousaf, Uzair Ahmed Qazi, Ishtiaq-ur-Rehman Congenital alveolar synechiae with cleft palate. Vol. 64, No. 6, June 2014
[4]. Sharan Naidoo1, Kurt W. BütowNonsyndromic palate Synechia with floor of mouth. Annals of Maxillofacial Surgery | January - June 2015 | Volume 5 | Issue 1
[5]. SeyyedHosseinMortazavi and Mohammad HoseinKalantarMotamedi Congenital fusion of Jaws Annals of Maxillofacial Surgery | January - June 2015 | Volume 5 | Issue 1

Abstract: Aim: The aim of this study was to evaluate the dissolving efficacy of four organic solvents on gutta-percha. Materials and methods: Seventy five samples of gutta-percha were prepared using a standardized stainless steel mould and divided into five groups for immersion in the different solvents i.e. Chloroform, Turpentine oil, Eucalyptol, GP solvent (safe plus) and in distilled water (control group) for 2, 5 and 10 minutes. The means of gutta-percha dissolution in the solvents were obtained by the difference between the pre-immersion original weight and the post-immersion weight in a digital analytical scale. Data was statistically analyzed by Analysis of Variance (ANOVA) and multiple comparisons with Scheffes test (p < 0.05)..............

[1]. Gomes Fabio de Almeida et al. Efficacy of gutta percha solvents used in endodontic retreatments. RSBO 2013 Oct-Dec; 10(4): 356-61.

[2]. Limongi O et al. Desobturacao do canal radicular: o desempenho dos solvents oleo de laranja e eucaliptol. RevistaGaucha de Odontologia 2004 Oct-Dec; 53(4): 341-5.

[3]. Zakariasen, K.L.; Brayton, S.M.; Collinson, D.M. Efficient and Effetive root canal retreatment without chloroform. J Canad Dent Assoc 1990; 56: 509-512.

[4]. Cohen S and Hargreaves KM. Pathways of the Pulp. 9th edition. London. Mosby; 2005. p. 372.

[5]. Wilcox LR, Krell KV, Madison S and Rittman B. Endodontic Retreatment. Evaluation of gutta percha and sealer removal and canal reinstrumentation. J Endod. 1987; 13: 453-7.

Abstract: This study was conducted to see the clinical effectiveness and complications of bi-canalicular intubation of silicone tube in congenital nasolacrimal duct obstruction in pediatric age group at Al-Ibrahim Eye, Hospital, ISRA Postgraduate Institute of Ophthalmology. 113 of 172 patients were treated from January, 2015 to January, 2016.The age range was 23.3 months to 10 years. According to protocol for bi-canalicular nasolacrimal silicone intubation in lacrimal surgery in our institute, the silicone tubes remained in situ for weeks on average14 weeks (SD 5.1)............

[1]. Bhandari S, Sengupta S, Yadalla D, Rajagopalan J, Velis GB, Talele D, Kushwaha S. Factors affecting treatment outcome in congenital nasolacrimal duct obstruction: A retrospective analysis from South India. Indian journal of ophthalmology. 2015 Oct;63(10):759.
[2]. Heichel J, Bredehorn-Mayr T, Stuhltraeger U, Struck HG. Dacryoendoscopy for lacrimal duct obstruction manifesting in childhood. J Clin Exp Ophthalmol. 2015;6(394):2.
[3]. M.Muhammed, Khokhar.A.M and Hameed.j. Comparison between early and late nasolacrimal stents for congenital nasolacrimal duct obstruction. Pak J Opthalmol 2016;Vol.32 (3): pp 165-168
[4]. Pemberton JD, Miller J, Commander J, Michalos P, Fay A. Electronically assisted nasolacrimal duct silicone intubation. Ophthalmic Plastic & Reconstructive Surgery. 2013 Jan 1;29(1):18-20.
[5]. Al-Faky YH, Al-Sobaie N, Mousa A, Al-Odan H, Al-Huthail R, Osman E, Al-Mosallam AR. Evaluation of treatment modalities and prognostic factors in children with congenital nasolacrimal duct obstruction. Journal of American Association for Pediatric Ophthalmology and Strabismus. 2012 Feb 29;16(1):53-7.

Abstract: Introduction: Carbapenems are among the few useful antibiotics against multidrug resistant Gram negative bacteria particularly those with extended spectrum beta-lactamase. Resistance to carbapenems is mediated by loss of outer membrane proteins and production of beta lactamase that is capable of hydrolyzing carbapenems. Methods: A total of 200 clinical isolates of Pseudomonas aeruginosa were tested for the presence of MBL. Detection of MBL was performed by various phenotypic methods like Modified Hodge Test, Imipenem(IMP)- EDTA Combined disc test and MBL E-test. The polymerase chain reaction (PCR) test was used for the detection of 3 genes encoding MBLs (IMP, VIM, NDM).........

Keywords: E-test, Modified Hodge test,MBL, Imipenem, blaIMP, blaVIM and bla NDM.

[1]. Lister PD, Wolter DJ, Hanson ND. Antibacterial‑resistant Pseudomonas aeruginosa: Clinical impact and complex regulation of chromosomally encoded resistance mechanisms. Clin Microbiol Rev 2009;22:582‑610.
[2]. Kali A, Srirangaraj S, Kumar S, Divya HA, Kalyani A, Umadevi S. Detection of metallo‑beta‑lactamase producing Pseudomonas aeruginosa in intensive care units. Australas Med J 2013;6:686‑93.
[3]. Hammami S, Boutiba‑Ben Boubaker I, Ghozzi R, Saidani M, Amine S, Ben Redjeb S. Nosocomial outbreak of imipenem‑resistant Pseudomonas aeruginosa producing VIM‑2 metallo‑beta‑lactamase in a kidney transplantation unit. Diagn Pathol 2011;6:106.
[4]. Marchiaro, P., Mussi, M. A., Ballerini, V., Pasteran, F.,Viale, A. M., Vila, A. J. and Limansky, A. S. Sensitive EDTA based microbiological assays for detection of metallo-β-lactamases in non-fermenting Gram negative bacteria. Journal of Clinical Pathology, 2005 43(11), 5648-5652.
[5]. Louis, B., Rice, Robert, A., Bonomo.(Arthur list not complete) Mechanism of resistance to antimicrobial agents. In: Murray, P. R. Baron, E. J. Landry, M. L. Jogensen, J. H. and Pfaller M. A. (eds.) Manual of Clinical Microbiology. 9th ed. Washington DC, ASM Press. 2007;pp.1125-1128.

Abstract: Acute appendicitis can occur any time during pregnancy. Ocuurs most often during 2nd trimester (45%), 30% during 1st trimester & remaining 25% in 3rd trimester. Overall incidence being 0.15 to 2.10 per 1000 pregnancies. Maternal deaths are rare in cases of simple appendicitis but increases to 2% with advanced pregnancy & perforated appendicitis while fetal mortality ranges from 0-1.5% in cases of simple appendicitis to 20-30% in perforated appendicitis. We are reporting case of a 31 week ANC patient with perforated appendix.

[1]. Wijesuriya LI. Imaging as an aid to the diagnosis of acute appendicitis. Malaysian Fam Physician. 2007; 2:106-9.
[2]. Guttman R, Goldman RD, Koren G. Appendicitis during pregnancy. Can Fam Physician 2004; 50:355-7. 3. Anderson REB, Lambe M. Incidence of appendicitis during pregnancy. Int J Epidemiol 2001; 30: 1281-5.
[3]. Borst AR. Acute appendicitis: Pregnancy complicates this diagnosis. JAAPA 2007; 20:36-41.
[4]. Humes DJ, Simpson J. Acute appendicitis. Br Med J 2006; 333:530-4.
[5]. Stone K. Acute abdominal emergencies associated with pregnancy. Clin Obstet Gynecol 2002;45:553-61.