iosr-JDMS   Volume-22 ~ Issue-8 ~ Aug. 2023

Abstract: Background: Diabetes alters the metabolic components of the body. Because of this metabolic abnormalities, many internal structures which depend on the metabolic products are also affected. Internal organelle dysfunction finally leads to organ dysfunction and death. Hypercalcemia is one of the important complication of diabetes mellitus. Hypercalcemia occurs in diabetes due to many mechanisms including insulin resistance. The heart is damaged by many conditions like hypertension, diabetes, dyslipidemia etc.Even though hypercalcemia is not defined as a risk factor for cardiac complications in older days, many trials and studies have proved that hypercalcemia will produce severe cardiac abnormality including systolic and diastolic dysfunction based on morphological changes in the heart. The heart is damaged by many conditions like hypertension, diabetes, dyslipidemia etc.......

Key Word: LVH, Remodelling,Diabeted mellitus

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[3]. Lorenzo C, Hanley AJ, Rewers MJ, Haffner SM. Calcium And Phosphate Concentrations And Future Development Of Type 2 Diabetes: The Insulin Resistance Atherosclerosis Study. Diabetologia. 2014;57(7):1366 74.
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Abstract: Objective: To demonstrate the equivalence of milrinone and levosimendan in the immediate postoperative period in patients with left ventricular systolic dysfunction. Design & Setting: A prospective equivalence study from December 2017 to December 2019 at Amrita Institute of Medical Sciences, Kochi. Patients undergoing OPCAB with EF <40% were included in this study. Participants & Intervention: Randomization done intraoperatively on table or in the ICU. Patients were received either Levosimendan bolus dose of 6 μg kg -1. given over 1 hr. followed by dosage of 0.05 to 0.2 μg kg -1 min -1 or Milrinone 30 μg kg -1 bolus over 1 hour followed by dosage of 0.3 to 0.5 μg kg -1 min -1. The primary outcome was 30-day mortality. Results: Total 78 patients......

Keywords: Milrinone, Levosimendan, Off pump coronary artery bypass surgery, Ischemic cardiomyopathy

[1]. Al-Ruzzeh S. Does Off-Pump Coronary Artery Bypass (OPCAB) Surgery Improve The Outcome In High-Risk Patients? A Comparative Study Of 1398 High-Risk Patients. Eur J Cardiothorac Surg. 2003 Jan;23(1):50–5.
[2]. Hadadzadeh M, Hosseini SH, Mostafavi-Pour-Manshadi SMY, Naderi N, Emami-Meybodi M. Effect Of Milrinone On Short Term Outcome Of Patients With Myocardial Dysfunction Undergoing Off-Pump Coronary Artery Bypass Graft: A Randomized Clinical Trial. 2013; 51(10): 681-686
[3]. Levin R, Degrange M, Mazo CD, Tanus E, Porcile R. Preoperative Levosimendan Decreases Mortality And The Development Of Low Cardiac Output In High-Risk Patients With Severe Left Ventricular Dysfunction Undergoing Coronary Artery Bypass Grafting With Cardiopulmonary Bypass. 2012;17(3):6.
[4]. Landoni G, Lomivorotov VV, Alvaro G, Lobreglio R, Pisano A, Guarracino F, Et Al. Levosimendan For Hemodynamic Support After Cardiac Surgery. N Engl J Med. 2017 May 25;376(21):2021–31.

Abstract: Introduction: Spinal anaesthesia (SA), also called spinal block or subarachnoid block is a type of regional anaesthesia, in which an opioid or local anaesthetic is injected into the subarachnoid space. Local anaesthetics include amides and esters. Postoperative pain relief was a vital issue with for local anesthestics like Ropivacaine. So, an adjuvant is added with Ropivacaine to provide prolonged postoperative analgesia with better intraoperative haemodynamic conditions with minimal side effects.....

Keywords : Ropivacaine, Dexmedetomidine, Spinal Anaesthesia, Lower limb surgeries, Sub arachnoid block

[1]. Han HS, Kang G, Kim JS, Choi BH, Koo SH. Regulation Of Glucose Metabolism From A Liver-Troperspective. Expmol Med 2016;48:E218.
[2]. Hickman IJ, Macdonald GA. Impact Of Diabetes On The Severity Of Liver Disease. Am J Med. 2007;120:829–834.
[3]. Perseghin G, Mazzaferro V, Sereni LP, Et Al. Contribution Of Reduced Insulin Sensitivity And Secretion To The Pathogenesis Of Hepatogenous Diabetes: Effect Of Liver Transplantation. Hepatology. 2000;31:694-703.
[4]. Megyesi C, Samols E, Marks V. Glucose Tolerance And Diabetes In Chronic Liver Disease. Lancet 1967;2:1051-6.
[5]. Muting D, Wohlgemuth D, Dorsett R. Liver Cirrhosis And Diabetes Mellitus. Geriatrics. 1969; 24(1): 91-99.

Abstract: INTRODUCTION: Anti-tubercular medications have been widely used to successfully treat the condition, but despite their effectiveness, there are still many problems that need to be resolved, including the need to manage the side effects of the drugs. One of the often encountered side effects and a significant reason for treatment noncompliance is hepatotoxicity. The degree of severity might range from a straightforward change in the liver's enzymes and acute hepatitis to acute liver failure with a very high death rate. MATERIALS AND METHODS: A Prospective, analytical study.....

Keywords: ATT , hepatotoxicity, Tuberculosis, hepatitis

[1]. Global Tuberculosis Report 2022. World Health Organization; 2022.
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[3]. Shang P, Xia Y, Liu F, Wang X, Yuan Y, Hu D, Et Al. Incidence, Clinical Features And Impact On Anti-Tuberculosis Treatment Of Anti-Tuberculosis Drug Induced Liver Injury (ATLI) In China. Cattamanchi A, Editor. Plos ONE. 2011 Jul 5;6(7):E21836.
[4]. Ch.Sreelatha. Association With Incidence Of Tuberculosis In Visakhapatnam District At 2012.
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Abstract: Background: Dengue Hemorrhagic Fever (DHF) is a severe form of dengue fever, a mosquito-borne disease that is a significant public health concern in tropical and subtropical regions. This study aimed to investigate the association between hematocrit levels and platelet counts in patients with DHF during a 2022 outbreak in Dhaka. Methods: This prospective observational study was conducted with a total of 239 patients diagnosed with DHF. Data were collected on sociodemographic characteristics, clinical presentations, comorbidities, and dengue diagnosis tests. Hematocrit levels and platelet counts were categorized, and their associations with dengue diagnosis tests were analyzed.......

Keywords: Dengue, Fever, Hematocrit, Platelet

[1]. Guzman MG, Harris E. Dengue. Lancet. 2015;385(9966):453-465. Doi:10.1016/S0140-6736(14)60572-9
[2]. Kraemer MUG, Sinka ME, Duda KA, Et Al. The Global Distribution Of The Arbovirus Vectors Aedes Aegypti And Ae. Albopictus. Elife. 2015;4:E08347. Doi:10.7554/Elife.08347
[3]. Rahman MM, Khan SJ, Tanni KN, Et Al. Knowledge, Attitude, And Practices Towards Dengue Fever Among University Students Of Dhaka City, Bangladesh. Int J Environ Res Public Health. 2022;19(7):4023. Doi:10.3390/Ijerph19074023
[4]. Srichaikul T, Nimmannitya S. Haematology In Dengue And Dengue Haemorrhagic Fever. Baillieres Best Pract Res Clin Haematol. 2000;13(2):261-276. Doi:10.1053/Beha.2000.0073
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Abstract: Objective: Objective of study was to compare the clinical efficacy of the Pro-argin in Colgate Sensitive Pro-Relief Toothpaste to that of 8% strontium acetate in Sensodyne Rapid action Toothpaste in reducing dentin hypersensitivity immediately and after two weeks, 1 month, and 2 months of twice-daily brushing. Methods: A randomised, controlled, double blind clinical trial was conducted with 70 participants clinically diagnosed with DH and equally randomized into two groups with parallel treatment assignment of Pro-Argin and 8% strontium acetate and tested for DH with air blast, mechanical, and water jet stimuli on SCHIFF cold air sensitivity scale (.....

Keywords: Dentine hypersensitivity, Strontium Acetate, Arginine

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[2]. Rees, J. S. & Addy, M. A Cross-Sectional Study Of Dentine Hypersensitivity. J. Clin. Periodont. 29, 997–1003.
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[6]. Gillam D, Talioti E. The Management Of Dentine Hypersensitivity. Dentine Hypersensitivity. Amsterdam: Elsevier; 2015. P. 45–76.

Abstract: Background: Oral squamous cell carcinoma is estimated to be the 6th most common cancer that accounts for 0.5 to 5% of all cancers in Europe, United States& Australia, but up to 45% cancers in India1,2,3,4. Most common sites being tongue and floor of mouth and most common etiological factors being tobacco and alcohol abuse5,6.The status of cervical lymph node at presentation is the single most important prognostic factor for patients with oral squamous cell carcinoma and presence of lymph node metastasis decrease survival rate by more than 50%......

Keywords: Squamous Cell Carcinoma (SCC), HPV, Lymph Nodes, Metastasis, Oral Cavity

[1]. Alkaisi A, Zaidan HA, Al Kabtan. The Predictive Value Of Tumor Depth For Cervical Lymph Node Metastasis In Oral Squamous Cell Carcinoma; Prospective And Retrospective Study In Iraq. J Cancer Sci Ther.2014; 6: 253-7.
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[4]. Ayas B, Saleem K, Azim W, Shaikh A.A Clinicopathological Study Of Oral Cancers. Biomedica 2011; 27:29-32.
[5]. Brandizzi D, Gondolfo M, Velazco ML. Clinical Features And Evolution Of Oral Cancer. Med Oral Patol Oral Cir Bucal.2008;13(9): E544-8.

Abstract: Tooth loss can occur by progressive caries, accidents, and gum problems. This can affect the beauty, smile, and chewing efficiency of an individual. This can be corrected by replacing the teeth with an artificial denture. Today, with the stress on the preventive measures in prosthodontics the use of overdenture has increased. Overdenture is a treatment option for individuals with very few teeth. So, preserving the root under the denture will maintain the proprioception, preserve the alveolar ridge by preventing residual ridge resorption and maintain denture stability. This will help to transfer the occlusal force along the tooth long axis and prevents the dislodgement of denture.Overdentures have....

[1]. Verma PR, Rawat M, Kinra MS, Kaur J, Kapoor H.Tooth Supported Overdenture-A Case Report.
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[3]. Brar, A., Mattoo, K.A., Singh, Y., Singh, M., Khurana, P.R.S., & Singh, M. Clinical Reliability Of Different Facial Measurements In Determining Vertical Dimension Of Occlusion In Dentulous And Edentulous Subjects. Int J Prosthodont Restor Dent, 2014: 4; 68-77.
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[5]. Ledger, E. On Preparing The Mouth For The Reception Of A Full Set Of Artificial Teeth. Br J Dent Sci, 1856:1; 90.

Abstract: Tuberculosis in its pseudo-tumor form is a rare entity. It can mimic at any point a bronchopulmonary neoplasia, both primary and secondary. The authors report the case of a patient admitted for a productive cough bringing back whitish sputum, with several episodes of low-abundance hemoptysis and dyspnea on exertion, in a context of declining general condition. Imaging supported a bronchogenic carcinoma while the trans-parietal biopsy biopsy confirmed tumor-like pulmonary tuberculosis.

Keywords: Tuberculosis; lung ; pseudo-tumor

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