iosr-JDMS   Volume-17 ~ Issue-1 ~ January-2018

Abstract: Objective: The aim of this study is to evaluate the result of type Itympanoplasy in geriatric age group( age> 60 years) in terms of closure of perforation and hearing improvement. Study Design: It's a prospective study done between July 2015 to December 2016 at Burdwan Medical College and Hospital. Materials and Method:40 new cases with mucosal type of Chronic OtitisMedia (COM) are included in this study. Type-I tympanoplasty done for all cases. At 6 months post operatively patients are examined for graft uptake status and hearing improvement. Result:among 40 patients 26 were male and rest 14 were female, mean age of our sample is 63.65 with SD10.39. Patients mostly complain about discharge from the affected ear(90%) and hearing loss(83%). The pre and post-operative pure tone mean are calculated at 0.5kHz, 1kHz, 2kHz and 3kHz frequency. Hearing gain is measured as the difference of mean of pre and post operative pure tone averages. Hearing gain is significant with p value <0.05 in all frequencies measured............

[1]. George GB, Saumil NM, Gerard K, Iain RS, Richard C, Willam SM. Chronic Otitis Media. Scott-Brown's Otorhinolaryngology, Head and Neck Surgery. 7th edition, vol 3. 2008; 237(c):3395-3445.
[2]. Nitin VD, Priyanka K, Sonali PK, Vivek VH, Priti RD, Kanchan SD, Rahul V, Prajakta SG. OUTCOME OF TYPE I TYMPANOPLASTY IN TUBOTYMPANIC CHRONIC SUPPURATIVE OTITIS MEDIA IN RELATION TO SITE AND SIZE OF TYMPANIC MEMBRANE PERFORATION. Journal of Evolution of medical and dental sciences. 2015 Nov; 93:15834-38.
[3]. Gyo K, Yanagihara N, Saiki T, HinohiraY.Chronicotitis media and tympanoplasty in aged patients. Aurisnasus larynx. 1990;17(3):141-8
[4]. Falagas ME, MourtzoukouEG, Vardakas KZ. Sex differences in the incidence and severity of respiratory tract infections. Respiratory Medicine 2007; 101:1845-1863.
[5]. Lin YS, Lin LC, Lee FP, Lee KJ.The prevalence of chronic otitis media and its complication rates in teenagers and adult patients.Otolaryngol-Head and Neck Surg 2009; 140:165-70.

Abstract: Objective: To study the incidence and clinical profile of triple negative breast cancer (TNBC) patients.MethodsPatients with histopathological evidence of breast cancer were evaluated for ER, PR HER-2 neu by immunohistochemistry. Their incidence and clinical profile were studied and result were analyzed statistically. Results: 196 out of 600 (32.67%) patients had TNBC. Patients with TNBC had younger age at presentation (51.48% were <50 years age) when compared to non-TNBC group (37.56% younger than 50). Patients with TNBC had significantly large tumor size (>5 Cm 24.85% vs 15.73%, p=0.012), higher node positivity (74.56% vs 64.86%, p=0.032), high recurrence whether distant or local (27.22% vs 16%, p=0.03), higher histopathological grade (55.90% vs 41.14%, p=0.05) when compared for non-TNBC group. 3 year DFS (Disease Free Survival) was significant lower in TNBC group (74.24% vs 85.66%, p<0.05). 5 year DFS rate was less in TNBC group, but not statistically significant...........

Keywords:TNBC (Triple Negative Breast Cancer), Non-TNBC( Non triple negative breast cancer), Hormone receptor, ER, PR, HER-2 neu.

[1]. Carey LA, Perou CM, Livasy CA, et al. Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study. JAMA 2006; 295: 2492–2502.
[2]. Perou CM, Sorlie T, Eisen MB, et al. Molecular portraits of human breast'tumours. Nature 2000; 406:747-752.
[3]. Reis-Filho JS, Tutt AN. Triple negative tumours: a critical review. Histopathological 2008; 52:108-118.
[4]. Vinayak W Patil, Rajeev Singhai, Amit V Patil, Prakash D Gurav, Department of Biochemistry, Grant Medical College and Sir JJ Group of Hospitals, Mumbai, India; Department of Surgery, Government Medical College, Miraj 2011. Breast Cancer: Targets and Therapy 2011:3 9–19.
[5]. Dent R, Trudeau, M, Pritchard K, et al. Triple-negative breast cancer: clinical features and patterns of recurrence. Clin Cancer Res 2007; 13:4429-4434...

Abstract: Aim: To study spectrum and histopathology of premalignant and malignant lesions of oral cavity. Introduction: Oral health is important for the quality of life of all individuals. Oral cancer is the most common cancer in the Indian subcontinent accounting for 40% of all cancers as compared to 2-4% of malignancies in the west. Materials And Methods: This was a retrospective study over a period of one year. Histopathological examination of total number of 302 casesfor a period of one year from January 2016 to December 2016 was done. Results: Out of 302 cases, 261 were malignant tumorsand 41were premalignant. Among malignant tumors most common was Well differentiated squamous cell carcinomaand among premalignant lesions most common was Leukoplakia with dysplasia. Peak incidence of tumors of both premalignant and malignant lesions was in the age group of 40-60yrs.

Keywords: Oral cavity lesions, premalignant, malignant, histopathology

[1]. Mehrotra R, Gupta A, Singh M, Ibrahim R. Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions.Mol Cancer. 2006 Mar 23;5:11.
[2]. B. W. Neville and T. A. Day, "Oral Cancer and Precancerous Lesions," CA A Cancer Journalfor Clinicians, Vol. 52, No. 4, 2002, pp. 195-215.
[3]. Liu W, Shen ZY, Wang LJ, Hu YH, Shen XM, Zhou ZT, et al. Malignant potential of oral and labial chronic discoid lupus erythematosus: a clinicopathological study of 87 cases. Histopathol. 2011;59:292-8.
[4]. Dr. Yasmin Khan, Dr. Shivaji D. Birare, " Study of Histopathology of the Tumour like Lesionsand Tumours of the Oral Cavity", International Journal of Science and Research (IJSR), https://www.ijsr.net/archive /v5i4/v5i4.php, Volume 5 Issue 4, April 2016, 915 - 920.
[5]. Dietrich T, Reichart PA, Scheifelea C. Clinical risk factors of oral leucoplakia in a representative sample of the US population. Oral Oncol. 2004;40:158-63

Abstract: The use of headgear has several clinical applications like distalization, restricting maxillary growth and anchorage control. The main being control of the vertical maxillary excess. In this article a 11 yr old patient with a high pull headgear for a period of 10 months is detailed. Cephalometrically the result indicates the use of high pull headgear causes both skeletal and dentoalveolar changes.

Keywords: High pull headgear, Maxillary splint, Intrusion

[1]. William R Profit- Contemporary Orthodontics- fifth edition.
[2]. Biomechanics & esthetic strategies in clinical orthodontics Ravindra Nanda, Elsevier Inc. copyright 2005.
[3]. Michael R Marcotte. Biomechanics in orthodontics, copyright 1990, Decker publisher.
[4]. Caldwell SF, Hymas TA, Timm TA. Maxillary traction splint: a cephalometric evaluation. Am J Orthod. 1984; 85(5):376-84.
[5]. Martins RP, Martins JCR, Martins LP, Buschang PH. Skeletal and dental components of class II correction with the bionator and removable headgear splint appliances. Am J Orthod Dentofacial Orthop. 2008; 134(6):732-41...

Abstract: The past couple of decades have witnessed one of the most rapid and extensive technological evolutions in dentistry.This paper aims to review the recent advances in the field of endodontics with respect to endodontic imaging, root canal preparation, disinfection and obturation..

Keywords: Endodontics, advances, dental treatment.

[1]. Kessler, S., Endodontics 1973: a review. J Dent Assoc S Afr, 1975. 30(12): p. 917-24.

[2]. Bellizzi, R. and W.P. Cruse, A historic review of endodontics, 1689-1963, part 3. J Endod, 1980. 6(5): p. 576-80.

[3]. de Souza, S.N., et al., Technological advances in endodontics: treatment of a mandibular molar with internal root resorption using a reciprocating single-file system. Gen Dent, 2017. 65(3): p. e5-e8.

[4]. Kishen, A., et al., Advances in endodontics: Potential applications in clinical practice. J Conserv Dent, 2016. 19(3): p. 199-206.

[5]. Pecora, J.D., et al., Detection of root canal isthmuses in molars by map-reading dynamic using CBCT images. Braz Dent J, 2013. 24(6): p. 569-74.

Abstract: Aim: To study clinical features and prognostic significance of various clinical, biochemical parameters and serial ascitic fluid cell count in SBP.. Study design: Prospective, observational, single centre, non-blind (open label). Place and duration of study: General Medicine Department, Maharaja's Institute of Medical Sciences, Nellimarla, Vizianagaram, Vizianagaram Dist, India from October 2014 to September 2016. Methodology: 50 patients admitted to MIMS General Hospital, Nellimarla, diagnosed as cirrhosis of liver with SBP were studied. SBP was diagnosed based on ascetic fluid cell PMN count of > 250. Serial ascitic fluid cell count was done at 0 hour, 24 hours, 48 hours, and at 5 days. The results were compared between the survivors and non-survivors and subjected to appropriate statistical analysis..............

Keywords: SBP and serial ascitic fluid cell count

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[3]. Wyle RJ. SBP a common complication of chronic active hepatitis. European ASS. Study liver, 1979:13.
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Abstract: Aims and objectives: To study the endoscopic biopsies of gastrointestinal lesions, to assess the overall utility of endoscopic biopsy in gastro- intestinal lesions and to study the various gastro intestinal lesions in relation to age and sex of the patients, site of occurance and distribution. Materials & methods: A total number of 100 cases of esophageal lesions are clinically identified and subjected to endoscopic biopsy, the departments of Gastroenterology and Pathology, Government General Hospital, Rangaraya Medical College, Kakinada, over a period of two years from 1999 to 2001.Observations: Out of 100cases of gastro intestinal lesions, male patients are 64 and female patients are 36 with male to female ratio of 1.8:1. In the100 cases of gastro intestinal lesions 43(43%) cases were esophageal lesions, 34(34%) cases were gastric lesions, 5(5%) cases were duodenal lesions and 18 .............

Key words: Endoscopic biopsies, gastro intestinal lesions, Pathological study.

[1]. Michael V, Sivak, Donna A. schleutermannGastroenterologic endoscopy text book, second edition Volume 1.
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[5]. Kobayashi S, Yoshii Y, Kasugai T; Biopsy and Brush cytology in the diagnosis of early gastric cancer". Endoscopy 1976;8:53-8...

Abstract: Aim: To study spectrum and histopathology of premalignant and malignant lesions of oral cavity. Introduction: Oral health is important for the quality of life of all individuals. Oral cancer is the most common cancer in the Indian subcontinent accounting for 40% of all cancers as compared to 2-4% of malignancies in the west. Materials And Methods: This was a retrospective study over a period of one year. Histopathological examination of total number of 302 casesfor a period of one year from January 2016 to December 2016 was done. Results: Out of 302 cases, 261 were malignant tumorsand 41were premalignant. Among malignant tumors, Most common was Well differentiated squamous cell carcinoma and among premalignant lesions. Most common was Leukoplakia with severe........

Keywords: Oral cavity lesions, premalignant, malignant, histopathology

[1]. Mehrotra R, Gupta A, Singh M, Ibrahim R. Application of cytology and molecular biology in diagnosing premalignant or malignant oral lesions.Mol Cancer. 2006 Mar 23;5:11.
[2]. B. W. Neville and T. A. Day, "Oral Cancer and Precancerous Lesions," CA A Cancer Journalfor Clinicians, Vol. 52, No. 4, 2002, pp. 195-215.
[3]. Liu W, Shen ZY, Wang LJ, Hu YH, Shen XM, Zhou ZT, et al. Malignant potential of oral and labial chronic discoid lupus erythematosus: a clinicopathological study of 87 cases. Histopathol. 2011;59:292-8.
[4]. Dr. Yasmin Khan, Dr. Shivaji D. Birare, " Study of Histopathology of the Tumour like LesionsandTumours of the Oral Cavity", International Journal of Science and Research (IJSR), https://www.ijsr.net/archive /v5i4/v5i4.php, Volume 5 Issue 4, April 2016, 915 - 920.
[5]. Dietrich T, Reichart PA, Scheifelea C. Clinical risk factors of oral leucoplakia in a representative sample of the US population. Oral Oncol. 2004;40:158-63..

Abstract: The aim of this retrospective study is to analyze the distribution pattern, etiology and prevalence of maxillofacial trauma in the population of Tiruvannamalai district, Tamilnadu.

Keywords: Maxillofacial injury, zygomatic complex, alcohol influence

[1]. Gassner R, Tuli T, Hächl O, Rudisch A, Ulmer H. Cranio-maxillofacial trauma: A 10 year review of 9543 cases with 21 067 injuries. J Cranio-Maxillofacial Surg. 2003;31(1):51-61. doi:10.1016/S1010-5182(02)00168-3.
[2]. Qudah MA, Bataineh AB. A retrospective study of selected oral and maxillofacial fractures in a group of Jordanian children. Oral Surg Oral Med Oral P 2002; 94; 310-4
[3]. Dibaie A, Raissian S, Ghafarzadeh S. Evaluation of maxillofacial traumatic injuries of forensic medical center of ahwaz, Iran, in 2005. Pakistan J Med Sci. 2009;25(1):79-82.
[4]. Fasola AO, Obiechina AE, Arotiba J. Soft Tissue Injuries of the Face: A 10 Year Review. Vol 29.; 2000.
[5]. Udeabor S, Akinmoladun VI, Olusanya A, Obiechina A. Pattern of midface trauma with associated concomitant injuries in a nigerian referral centre. Niger J Surg Off Publ Niger Surg Res Soc. 2014;20(1):26-29..

Abstract: Introduction: Corticosteroids are widely used in peripheral nerve blocks for acute pain control and are routinely injected into the epidural space for treating radicular pain with a reliably acceptable side effect profile .This study has been undertaken to evaluate the adjuvant use of dexamethasone in supraclavicular brachial plexus nerveblocks with a focus on block characteristics. Aims And Objectives: To evaluate the efficacy of Dexamethasone as an adjuvant to Lidocaine with Adrenaline in supraclavicular brachial plexus block in terms of Onset of sensory block,Onset of motor blockade,Duration of sensory block ,Duration of motor blockade. Conclusion: In conclusion, admixture of..........

Keywords: Dexamesone, Brachial Plexus Block, Lidocaine1.5%..

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[2]. Shrestha BR, Maharjan SK, Tabedar S: Supraclavicular brachial plexus block with and without dexamethasone - A comparative study. Kathmandu University Medical Journal (2003) Vol. 1, No. 3, 158-160.
[3]. Biradar PA, Kaimar P, Gopalakrishna K. Effect of dexamethasone added to lidocaine in supraclavicular brachial plexus block: A prospective, randomised, double-blind study. Indian J Anaesth2013; 57:180-184.
[4]. Parrington SJ, O'Donnell D,Chan VW, Brown-Shreves D, Subramanyam R, Qu M,et al. Dexamethasone added to mepivacaine prolongs the duration of analgesia after supraclavicular brachial plexus blockade.RegAnesth Pain Med 2010;35:422-6.
[5]. Movafegh A, Razazian M, Hajimaohamadi F, Meysamie A.Dexamethasone added to lidocaine prolongs axillary brachial plexus blockade.AnesthAnalg 2006;102:263-7.

Abstract: Diabetic foot ulcer is a historically important disease which has been managed in myriad ways over the ages. Dressings form an important aspect of the treatment protocol. Here efficacy some of the newer dressings-namely collagen, alginate, topical hydrogel were compared with that of the conventional saline dressing. The study was done over a period of 6 months from March to October 2016 among 100 consenting diabetic foot ulcer patients admitted to Govt.Rajaji Hospital, Madurai. It was found out that patients in the collagen group had faster development of granulation tissue, shorter hospital stay and overall better healing. Even though the search for the ideal dressing material continues, among the materials studied here collagen appears superior..

[1]. Gibbons GW. The diabetic foot: amputations and drainage of infection. JVasc Surg.1987;6(5):791-793
[2]. Schmidt RJ (1986) "Alginate dressings".Pharmaceutical Journal 236: 36-37
[3]. Jones V (1999) "Alginate Dressings and Diabetic Foot Lesions".The Diabetic Foot 2(1): 8-14
[4]. SarkarPK.Ballantyne S.Management ofLeg Ulcer.Postgrad Med Journal 2000;76: 674-682
[5]. Higgins KR, Ashry HR. Wound dressing and Topical Agents.ClinPodiatr Med Surgery 1995; Jan; 12 (1): 31-40.

Abstract: Endometrial carcinoma is predominantly a disease of postmenopausal women .Only 1-6% occur in women under 40 years. Majority of cases are associated with hype- estrogenic states. Younger patients present with clinical challenges as there is loss of fertility and surgical menopause with standard surgical treatment. Young women have an early stage distribution at diagnosis and a good prognosis. This is a retrospective study to emphasize the need for endometrial evaluation in young women presenting with abnormal uterine bleeding .A retrospective case study was carried out at our tertiary health care centre, Sri Ramachandra Medical Centre And Research Institute(2015-2017)............

Keyword: Endometrial carcinoma, prognosis, risk factors, treatment, young women

[1]. Kaku T, Matsumura M, Sakai K, et al. Endometrial carcinoma inwomen 65 years of age or older: a clinical study. Eur J Gynaecol.1996;17:35
[2]. Fadhlaoui A, Hassouna JB, Khrouf M, Zhioua F, Chaker A (2010) Endometrial adenocarcinoma in a 27-years old women. Clin Med Insights Case Rep 3: 31-39.
[3]. Shyamala G, Lavanya R, Prashanth A, Rajagopal K, Kurien NJ, et al. (2008) An unusual case of endometrial cancer in a young lady. Int J Oncol 5: 1.
[4]. Gupta M, Malik TR, Wani ML, Lone MM (2012) Endomerial carcinoma in a 20 years old female: a rare presentation. J Clin Case Rep 2: 9.
[5]. Ota T, Yoshida M, Kimura M, Kinoshita K (2005) Clinicopathologic study of uterine endometrial carcinoma in young women aged 40 years and younger. Int J Gynecol Cancer 15: 657-662.

Abstract: Background: Many worldwide studies have investigated the anatomical differences between males and females. One of the most areas was studied is the morphological differences in the bony pelvis. Apart from their medical and anatomical values these information had been used in forensic and anthropological studies. Objectives: This study is held to shed a light in presence of difference in bony pelvis regarding the subpubic angle among Sudanese males and females subjects. Methods: A sample of 54 males and 53 females X-ray pelvises had been collected, examined and the subpubic angle was measured for each individual. Results: The range of the subpubic angle in male was found (82 to 128) and the mean was 106. In females the range was found (104 to 170) and the mean was 140 with significant statistical difference. Conclusion: The anatomical difference of the subpubic angle in males and females was significant in this study. Our results are comparable to that obtained from other regional studies held in Africa with some minor differences that may reflect ethnic variation.

Keywords: Anthropological studies, Bony pelvis, Morphological differences, Subpubic angle, X-ray.

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Abstract: The pituitary gland width was measured by Magnetic Resonance Imaging Technique, in 69 individuals, the data was evaluated according to sex and age groups. In all cases the mean value of the female pituitary gland width (11.77) mm, which was higher than male (9.60) mm. A gradual increase in the pituitary gland width was noted in the age group (20-29) yrs old, while a decrease in the pituitary width was noted after age (50-59) yrs.Nevertheless, there was a conspicuous increase in the pituitary gland width in the 61yrs in females, and 67 yrs in male, this study reflect the role of puberty and lactation and their relation to the pituitary width. This study opened new doors for more researches in this field to use other specific sciences like histology and physiology of the pituitary cells in details to determine which lobe or cell has got changes exactly.

Keywords: Adnohypophysis, Magnetic Resonance Imaging, pituitary gland, pituitary width, Neurohypophysis

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Abstract: The aim of this research was to determine the most common anatomical form of roots and canals configuration of the maxillary first premolar among Sudanese population. The study was an observational descriptive in nature. Diagnostic periapical radiographs were used along with clinical findings. Data was collected from departments of restorative dentistry in some Khartoum state's clinics and hospitals. The study included a total of 80 patients, of which (30) were males and (50) were females with a minimum age of 15 years and a majority ranging between 26 and 36 years. It revealed that 30 (37.5 %) of the maxillary first premolars under study had a single root, while 49 (61.25%) had two roots and only one tooth...........

Keywords: Buccal canal, First premolar, Maxillary, Palatal canal, Periapical.

[1]. DEFINITION OF MAXILLARY FIRST PREMOLAR. AVAILABLE FROM: HTTPS://EN.WIKIPEDIA.ORG/WIKI/MAXILLARY FIRST PREMOLAR
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[3]. Ferit Koçani, Blerim Kamberi, Edmond Dragusha, Et Al. Correlation Between Anatomy And Root Canal Topography Of The First Maxillary Premolar, Kosovar Population.Open Journal Of Stomatology, 2014; 4: P. 332-339.
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Abstract: TYPE1Diabetes mellitus is a form of diabetes in which there is absolute deficiency of the hormone insulin due to autoimmune destruction of the Beta cells of the pancreas.This is a prospective study conducted in Type1diabetic patients to know about the disease awareness and its complications if left untreated.It is a validated Questionnaire study conducted by us in theDiabetic Outpatient department

Keywords: Type1 Diabetes, Questionaire, Awareness, Health education importance, sick day regime

[1] M Ozaki, Y. Adachi, Y. Iwahori, and N. Ishii, Application of fuzzy theory to writer recognition of Chinese characters, International Journal of Modelling and Simulation, 18(2), 1998, 112-116.
Note that the journal title, volume number and issue number are set in italics. Books:
[2] R.E. Moore, Interval analysis (Englewood Cliffs, NJ: Prentice-Hall, 1966).
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Abstract: Patients with oral squamous cell carcinoma (OSCC) respond to treatment modalities such as surgery and radiochemotherapy. Clinicians are, however, continuously testing other treatment combinations to see if they can improve the therapeutic results, lessen side effects or quality of lives in cancer survivors. The aim of this study was to investigate the effectiveness of prescription of Ganoderma lucidum powder and/or extract on OSCC patients undergoing radiochemotherapy treatment following surgical removal of primary cancerous tissues. After surgery, G. lucidum was prescribed in three forms: G. lucidum powder capsule (500 mg/capsule), brushing teeth with dental paste (containing 0.5% extract) and drinking tea (containing 0.2% extract) thrice daily for three months.............

Keywords: Squamous Cell Carcinoma, Palliative Treatment, G. lucidum, LPO, TNF

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