iosr-JDMS   Volume-21 ~ Issue-3 ~ March 2022

Abstract: Purpose: to Compare between micro tensile and micro shear bond strength of three adhesive systems (Futurabond U adhesive, Single Bond Universal adhesive, Swiss TEC SL Bond) to dentin. Materials&Methods: sixty freshly extracted sound human third molars were selected from patients aged 20- 25 years. The occlusal enamel is removed to expose the occlusaldentin, The prepared specimens were randomly divided into three groups according to the type of adhesive used (n=20 each): each adhesive were applied on dentin surface then composite resin were applied . All specimens were stored in distilled water for 24 hours. specimens of each group were subjected to......

Keywords: micro tensile bond strength , micro Shear bond strength, adhesive system , Occlusal dentin, Thermocycling.

[1]. Bhuva B, Giovarruscio M, Rahim N, Bitter K, Mannocci F. The restoration of root filled teeth: A review of the clinical literature. Int Endod J. 2021;54:509–35.
[2]. Hamdy TM. Modifications of dental adhesive systems. J Dent Health Oral Disord Ther. 2018;9:5.
[3]. Plotino G, Turchi M. Strategies for the Restoration of Minimally Invasive Endodontically Treated Teeth. InMinimally Invasive Approaches in Endodontic Practice 2021; 171-201.
[4]. Jayasheel A, Niranjan N, Pamidi H, Suryakanth MB. Comparative Evaluation of shear Bond Strength of universal Dental Adhesives-An in vitro study. J Clin Exp Dent. 2017;9: 892-95.
[5]. Morsy SM, Moustafa ES, Elsharkawy M. Micro Shear Bond Strength of Universal Dental Adhesives to Dentin Using Different Etching Modes (In Vitro Study). Alex Dent J. 2020;45:84–90

Abstract: Background: Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver and sixth most common cancer in the world. The morphological features of hepatocellular carcinoma often overlap with those of metastatic tumors and intrahepatic cholangiocarcinoma. There is a limited number of immunohistochemical biomarkers used for distinguishing HCCs from non HCCs. Arginase-1 has been described in literatures as a potential immunohistochemical marker of hepatocellular differentiation. Only few studies have evaluated Arg-1 expression as a distinguishing marker of HCCs from nonHCCs .The aim of this study is to find out the expression....

Key Word: Arginase1,Hepatocellular carcinoma,immunohistochemistry

[1]. McKnight R, Nassar A, Cohen C, Siddiqui MT. Arginase-1: a novel immunohistochemical marker of hepatocellular differentiation in fine needle aspiration cytology. Cancer Cytopathol. 2012 Aug 25;120(4):223-9. doi: 10.1002/cncy.21184. Epub 2012 Feb 1. PMID: 22298472[2]. Obiorah,.Chahine,J.,KO, K.,Park B.,Deguzman,J,Kallakury,Prognostic Implications of Arginase and Cytokeratin 19 Expression in Hepatocellular Carcinoma After Curative Hepatectomy: Correlation With Recurrence-Free Survival. Gastroenterol Res. 2019;12(2):78-87.
[3]. Quaglia, A.Hepatocellular carcinoma: a review of diagnostic challenges for the pathologist. Journal of Hepatocellular Carcinoma, Volume 5, 99–108. doi:10.2147/jhc.s159808.
[4]. Shams U M,Loya A,Waqas O,Rias S. Arginase-1: A Useful Immunohistochemical Marker in Differentiating Hepatocellular Carcinomas from Non-Hepatocellular Carcinomas of Liver S.Z.P.G.M.I. Vol: 31(1): pp. 41-46, 2017.
[5]. Yan BC Gong C, Song J, et al. Arginase-1: a new immunohistochemical marker of hepatocytes and hepatocellular neoplasms. Am J Surg Pathol 2010;34:1147–54.

Abstract: The aim of this study is to evaluate the effect of root canal preparation with XP-endo Shaper (XPS) used at high rotation speed on the fracture resistance of roots. Fifty mandibular canine teeth were decoronated to obtain a standard root length of 14 mm. They were randomly divided into 4 experimental groups and 1 control group (n=10): no preparation, preparation with XPS at 1000 rpm and 3000 rpm, preparation with XPS at 1000 rpm and 3000 rpm and filling with cold lateral compaction. Data were statistically analysed using 1-way analysis of variance (P=.05) The highest fracture resistance was observed in the control group, followed by the group with root canal preparation and root canal filling at 3000 rpm. The use of the XPS at 1000 rpm and 3000 rpm, or filling the root canals with epoxy resin-based sealers had no significant effect on the fracture resistances of the roots..

KEY WORDS: Fracture Resistance; High Rotation Speed; XP-Endo Shaper; Root Fracture

[1]. Lam PP, Palamara JE, Messer HH. Fracture strength of tooth roots following canal preparation by hand and rotary instrumentation. J Endod. 2005; 31: 529-32.
[2]. Fuss Z, Lustig J, Katz A, Tamse A. An evaluation of endodonti- cally treated vertical root fractured teeth: impact of operative procedures. J Endod. 2001; 27: 46-8.
[3]. Karapinar Kazandag M, Sunay H, Tanalp J, Bayirli G. Fracture resistance of roots using different canal filling systems. Int Endod J. 2009; 42: 705-10.
[4]. Cobankara FK, Ungor M, Belli S. The effect of two different root canal sealers and smear layer on resistance to root fracture. J Endod. 2002; 28: 606-9.
[5]. Uzunoglu E, Aktemur S, Uyanik MO, Durmaz V, Nagas E. Effect of ethylenediaminetetraacetic acid on root fracture with respect to concentration at different time exposures. J Endod. 2012; 38: 1110–3

Abstract: SARS-CoV2 infection, since its outbreak in Wuhan of Hubei Province, China in December 20191 has been declared by the World health Organization (WHO) as a public health emergency of International concern and declared a pandemic on March 11, 2020.2 Although children and adolescents have less severe presentations as compared to children, they are at a risk of developing secondary conditions. Multi-system inflammatory syndrome in children (MIS-C) is an emerging syndrome which was first reported in April 2020 by paediatricians in the United Kingdom.3 It is usually seen within 2-6 weeks after SARS-CoV-2 ( severe acute respiratory syndrome coronavirus 2/COVID-19) infection....

[1]. World Health Organization (WHO). Novel Coronavirus (2019-nCoV) Situation Report – 1. Available at: https:// www.who.int/docs/default-source/coronaviruse/situation ˇreports/20200121-sitrep-1-2019-ncov.pdf.
[2]. World Health Organization (WHO). Director-General's ope ning remarks at the media briefing on COVID19 - March 2020. Available at: https://www.who.int/director-general/ speeches/detail/who-director-general-s-opening-remarksˇat-the-media-briefing-on-covid-19---11-march-2020..
[3]. Riphagen S, Gomez X, Gonzalez-Martinez C, Wilkinson N, Theocharis P. Hyperinflammatory shock in children during COVID-19 pandemic. The Lancet. 2020;395(10237):1607-1608.
[4]. Multisystem Inflammatory Syndrome in Children (MIS-C) Interim Guidance [Internet]. Aap.org. 2022 [cited 4 February 2022]. Available from: https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/clinical-guidance/multisystem-inflammatory-syndrome-in-children-mis-c-interim-guidance/

Abstract: Background: Cancer antigen 15-3 (CA 15-3) is used to monitor response to breast cancer treatment and disease recurrence.The range of serum CA 15-3 is less than 30 U/mL. The upper limit of the reference range varies depending on the laboratory and kit used for the test. Values of CA 15 -3 obtained with different assay kits, methods, or laboratories cannot be used interchangeably.CA 15-3 levels are most commonly used to monitor metastatic carcinoma breast during active therapy. Tumor marker 15-3 levels must be used in conjunction with the history, physical....

KEY WORDS: CA15-3, prognostic marker,breast cancer

[1]. Swart R. Breast Cancer. Medscape Drugs and Diseases.
[2]. Bon GG et al. Clinical and technical evaluation of ACS™BR serum assay of MUC1 gene-derived glycoprotein in breast cancer, and comparison with CA15-3 assays. Clinical Chemistry. 1997.
[3]. Wu JT. Expression of monoclonal antibody-defined tumor markers in four carcinomas . Ann Clin Lab Sci. 1989 Jan-Feb.
[4]. Duffy MJ, Shering S, Sherry F, McDermott E, O'Higgins N. CA 15-3: a prognostic marker in breast cancer. Int J Biol Markers. 2000 Oct-Dec.
[5]. Klee GG, Schreiber WE. MUC1 gene-derived glycoprotein assays for monitoring breast cancer (CA 15-3, CA 27.29, BR): are they measuring the same antigen?. Arch Pathol Lab Med. 2004 Oct.

Abstract: Background: Atopic dermatitis (AD) is the most common chronic relapsing skin disease in children. It affects 10-20% of children worldwide and commonly occurs in families with a history of asthma, allergic rhinitis, and food allergies. The study aimed to determine the prevalence and clinical profile of atopic dermatitis in children attending the dermatology clinic in UPTH, Port Harcourt. Materials and Methods: A retrospective review of the case notes of all children diagnosed with atopic dermatitis over a three (3) year period was done.
Results: Among the 486 children seen in the dermatology clinic over the study period, 69 (14.2%) were diagnosed with atopic dermatitis. There were....

KEY WORDS:Atopic dermatitis, Children, Dermatology clinic, Nigeria

[1]. Leung DYM, Sicherer SH. Atopic Dermatitis (Atopic Eczema). In Kliegman RM, St. Geme JW, Blum NJ, Shah SS, Tasker RC, Wilson KM, Behrman RE (eds.) Nelson Textbook of Pediatrics. 21st ed. Philadelphia: Elsevier; 2020. 1209-1216.
[2]. Nutten S. Atopic Dermatitis; Global Epidemiology and Risk Factors. Ann Nutr Metab 2015, 66(suppl 1:8-16.
[3]. Dhar S. Atopic Dermatitis. In Color Atlas and synopsis of Pediatric Dermatology. 3rd ed. New Delhi: Jaypee Brothers Medical Publishers,2015. 146-148.
[4]. Bagazgoitia L, Gutierrez M, Garcia BCHernandez MA, Torrelo A. Epidemiologic, pathogenic, clinical and diagnostic aspects of atopic dermatitis. Is it possible the prevention? Rev Pediatr Aten Primaria 2009; 11:31-47
[5]. Odhiambo JA, Williams HC, Clayton TO, Robertson CF, Asher MI. ISAAC Phase Three Study Group Global variations in prevalence of eczema symptoms in children from ISAAC Phase Three. J Allergy Clin Immunol 2009;124:1251.e23-1258.e23

Abstract: Gastric cancer is one of the commonest cancers seen in day to day surgical practice. In a resource poor country like India where the screening services for gastric cancer are not frequent, many patients present late with advanced stage of the disease. The role of gastric bypass as a palliative procedure in advanced gastric cancer is controversial. This study was conducted at a tertiary care hospital of Odisha to study the role of gastric bypass as a palliative procedure as compared to resection in a case of advanced gastric cancer. In our study, in-hospital morbidity rate for the entire study group was 24.45% which is similar to the rates obtained in other........

KEY WORDS: stomach, gastric bypass, palliation, resection,

[1]. L o NN, Kee SG, Nambiar R (1991) Palliative gastrojeju- nostomy for advanced carcinoma of the stomach. Ann Acad Med Singapore 20:356–358
[2]. D oglietto GB, Pacelli F, Caprino P, Alfi eri S, Carriero C, Malerba M et al (1999) Palliative surgery for far advanced gastric cancer: a retrospective study on 305 consecutive pa-tients. Am Surg 65:352–355
[3]. M edina-Franco H, Contreras-Saldivar A, Ramos-De LaMedina A, Palacios-Sanchez P, Cortes-Gonzalez R, UgarteJA (2004) Surgery for stage IV gastric cancer. Am J Surg187: 543–546
[4]. Miner TJ, Brennan MF, Jaques DP (2004) A prospective, symptom related, outcomes analysis of 1022 palliative procedures for advanced cancer. Ann Surg 240 719–726
[5]. Stephens MR, Lewis WG, White S, Blackshaw GR, Ed- wards P, Barry JD, Allison MC (2005) Prognostic significance of alarm symptoms in patients with gastric cancer. Br - J Surg 92:840–846

Abstract: Background: Stomal necrosis following stomal reconstruction may be due to venous congestion which can be managed conservatively or due to vascular compromise which warrants an redo-laparotomy for stomal revison. This paper describes an simple bed side test using an test tube and hand held flash light to determine the vascular integrity of the stoma. This technique is life saving, simple, safe and cost effective in resource poor settings. Materials and Methods: Patients who fulfill the inclusion criteria will be recruited for the study after obtaining informed written consent from the patient. Tube test will be performed. Effectiveness of using tube test in detection of stomal necrosis will be evaluated.......

Key Word: stoma, tube test, mucosal excision, re-laparotomy

[1]. Kann BR, Cataldo TC. Early stomal complication. Clin Colon Rectal Surg 2002;15:191–198
[2]. Devi Mukkai Krishnamurty, MD1 Jeffrey Blatnik, MD2 Matthew Mutch, MD1. stoma complications. Clin Colon Rectal Surg 2017;30:193–200.
[3]. Formijne Jonkers HA, DraaismaWA, Roskott AM, van Overbeeke AJ, Broeders IA, Consten EC. Early complications after stoma formation: a prospective cohort study in 100 patients with 1-year follow-up. Int J Colorectal Dis 2012;27(8):1095–1099
[4]. Harris DA, Egbeare D, Jones S, Benjamin H, Woodward A, Foster ME. Complications and mortality following stoma formation. Ann R Coll Surg Engl 2005;87(6):427–431 5
[5]. Bafford AC, Irani JL. Management and complications of stomas. Surg Clin North Am 2013;93(1):145–166

Abstract: Background: Orthopedic implant site infection is one of the major constituent of surgical site infection associate with high morbidity and mortality. Incidence of orthopedic implant infection varies from 0.5-2% in fixation of closed fractures and 30% after fixation of open fractures. Infection can occur by infected implant, aseptic failure, predisposing patient conditions, biofilm production on implant by bacteria.
Methods: A prospective study was carried out on the patients who had undergone orthopedic implant surgeries and present with signs and symptoms of implant site infections admitted a tertiary care hospital in Punjab from January 2020- June 2021. The aim of this study was to determine the bacteriological profile of orthopedic implant site infections, to study the antimicrobial susceptibility pattern and biofilm production by bacterial isolates........

[1]. Jain A, Bhatawadekar S, Modak M. Bacteriological profile of surgical site infection from a tertiary care hospital, from Western India. Indian J Appl Res 2014; 4(1): 397-400.
[2]. LakshminarayanaSA,Chavan KD, Prakash R, Sangeetha S. Bacteriological profile of orthopedic patients in a tertiary care hospital, Bengaluru. International Journal of Science & Research, 2015; 4(6):1504-8.
[3]. Khosravi AD, Ahmadi F, Salamnzadeh S. Study of Bacteria Isolated from orthopedic implant infections and their antimicrobial susceptibility pattern.
[4]. Brady R, Calhoun J, Leid J, Shirtliff, M. Infections of Orthopaedic Implants and Devices. Springer Berlin Heidelberg. 2008;1-41.Research Journal of Microbiology, 2009; 4 (4): 158-63.
[5]. Washington Jr, Allen S, Janda W, Koneman E, Procop G, Schreckenberger P et al., Introduction to microbiology: part 1; The Role of Microbiology Laboratory in the Diagnosis of Infectious Diseases: Guidelines to Practice and Management; Koneman's colour atlas and textbook of Diagnostic Microbiology. 6th Ed, Philadelphia: Lippincott Williams and Wilkins;2006;1- 66.

Abstract: Background: Malnutrition is common at hospital readmission and tends to worsen during hospitalization. As critical illness has a major impact on nutritional status of children it is imperative to be aware of the nutritional status of the children at readmission in order to direct the health care strategies towards the overall improvement of these little lives. Materials and Methods: This is hospital based cross sectional study in cases readmitted to PICU. The study was carried out in 100 pediatrics readmitted subjects. Inclusion criteria for study participant's included age group between 1month to 12 years.......

Key Word: Pediatric Intensive Care Unit, Readmission

[1]. Adam S, Batson S. A study of problems associated with the delivery of enteral feed in critically ill patients in five ICUs in the UK. Intensive Care Med. 1997;23:261-266.
[2]. Agarwal DK, Agarwal KN. Physical growth in Indian affluent children (Birth – Six years). Indian Paediatrics. 1994; 31, 377-413.
[3]. Albers MJ, Steyerberg EW, Rietveld T, Tibboel D. Clinical relevancy of nonurinary nitrogen excretion in newborns and infants after digestive tract surgery. J Parenter Enteral Nutr 2003;27:327-32.
[4]. Alexander JW, Gonce SJ, Miskell PW, Peck MD, Sax H. A new model for studying nutrition in peritonitis: the adverse effect of overfeeding. Annals of Surgery 1989;209(3):334–40.
[5]. Ash JL, Gervasio JM, Zaloga GP, Rodman GH. Does the quantity of enteral nutrition affect outcomes in critically ill trauma patients. Nutrition in Clinical Practice 2005;29 Suppl(1):10–11.

Abstract: Oral squamous papilloma (OSP) is a benign tumor and it is one of the most common lesions of the oral mucosa usually seen in hard and soft palate of adults. It is mostly asymptomatic with slow progressive changes in size. It often raises suspicion of malignancy in clinicians and patients and can lead to inappropriate management. Squamous papilloma are common lesions of the oral mucosa with a predilection for the mucosa of the hard and soft palate. As an oral lesion, it raises concern because of its clinical appearance, which may mimic exophytic carcinoma, verrucous carcinoma or condyloma acuminatum. It is related to human papilloma virus even though the controversy regarding its pathogenesis still exists. It most often occurs on the tongue and the hard palate. It is important to diagnose it correctly as it may mimic malignant lesions. This article describes a case of squamous papilloma in the oral cavity..

Keywords –Oral squamous papilloma , White keratotic lesion, Ulceroproliferative tissue, Verricuos carcinoma.

[1]. Du M, Nair R, Jamieson L, Liu Z, Bi P. Incidence trends of lip, oral cavity, and pharyngeal cancers: global burden of disease 1990–2017. Journal of dental research. 2020 Feb;99(2):143-51.
[2]. Parkin DM, Bray F, Ferlay J, Pisani P. Estimating the world cancer burden: Globocan 2000. International journal of cancer. 2001 Oct 15;94(2):153-6.
[3]. Marur S, D'Souza G, Westra WH, Forastiere AA. HPV-associated head and neck cancer: a virus-related cancer epidemic. The lancet oncology. 2010 Aug 1;11(8):781-9.
[4]. Jaju PP, Suvarna PV, Desai RS. Squamous papilloma: Case report and review of literature. Int J Oral Sci. 2010; 2(4):222-5.
[5]. Nai R, Ra KK. An unusual presentation of squamous papilloma on the buccal mucosa. Indian Journal of Multidisciplinary Dentistry. 2014 May 1;4(3).

Abstract: Guillain-Barré syndrome (GBS) is an acute, frequently severe, and fulminant polyradiculoneuropathy that is autoimmune in nature. It has two axonal variants, which are often clinically severe—the acute motor axonal neuropathy (AMAN) and acute motor sensory axonal neuropathy (AMSAN) subtypes..

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