iosr-JDMS   Volume-23 ~ Issue-5 ~ May 2024

Abstract: Background: Chronic hepatitis C virus (HCV) infection is a major public health problem. Psychiatric side effects induced by antiviral treatment (interferon alpha) of this condition are frequent (20-30%). These are mainly mood disorders, which interfere with the management of the disease. Psychiatric evaluation and follow-up are necessary to treat any associated psychiatric disorders, and thus enable better management of patients with hepatitis c virus. The aim of the study was to identify and diagnose interferon-alpha-induced psychiatric disorders, and to assess their impact on compliance with antiviral treatment, through a bi-disciplinary approach involving a hepato-gastroenterologist and a psychiatrist......

Keywords: Procedure. Interferon alpha. Psychiatric disorders

[1]. Afssaps. Therapeutic Update. Evaluation And Management Of Psychiatric Disorders In Adult Patients Infected With Hepatitis C Virus And Treated With (Peg) Interferon Alfa And Ribavirin. May 2008.
[2]. Lang Jp, Michel L, Melin P, Schoeffler M, Gauchet A, Cartier V, Et Al. Management Of Psychiatric Disorders And Addictive Behaviors In Patients With Hepatitis C In France.
[3]. France. Gastroenterrol Clin Bio 2009; 33: 1-7.
[4]. Castera L, Constant A, Henry C, Champbenoit P, Bernard Ph, De Ledinghen V, Et Al. Impact On Adherence And Sustained Virological Response Of Psychiatric Side Effects During Peginterferon And Ribavirin Therapy For Chronic Hepatitis C. Aliment Pharmacol Ther 2006; 24: 1223-30.
[5]. Constant A, Castéra L, Dantzer R, Couzigou P, De Ledinghen V, Demotes-Mainard J, Et Al. Mood Alterations During Interferon-Alfa Therapy In Patients With Chronic Hepatitis C: Evidence For An Overlap Between Manic/Hypomanic And Depressive Symptoms. J Clin Psychiatry 2005 ; 66 : 1050-7.

Abstract: Introduction: Ameloblastoma ranks as the second most prevalent neoplasm arising from odontogenic epithelial tissues within the maxillofacial region, marked by a notable propensity for local recurrence following excision. Recurrences often manifest within the mandible, soft tissues, and even in various reconstructive materials employed. However, instances of ameloblastoma recurrence within autogenous iliac bone grafts remain scarcely documented in the literature.....

Keywords - Ameloblastoma, Recurrence, Autograft, Iliac graft, Bone graft, Adenoid ameloblastoma

[1] Angadi Pv. Head And Neck: Odontogenic Tumor: Ameloblastoma. Atlas Genet Cytogenet Oncol Haematol. 2011;15(2):223-9.
[2] Barnes L. World Health Organization Classification Of Tumours. Pathology And Genetics Of Head And Neck Tumours. 2005;232-5.
[3] De Ac Almeida R, Andrade Ed, Barbalho Jc, Vajgel A, Vasconcelos Bd. Recurrence Rate Following Treatment For Primary Multicystic Ameloblastoma: Systematic Review And Meta-Analysis. International Journal Of Oral And Maxillofacial Surgery. 2016 Mar 1;45(3):359-67.
[4] Gold L. Biologic Behavior Of Ameloblastoma. Oral Maxillofac Surg North Am 1991;3:21-5.
[5] Adekeye Eo, Mccallum Lavery K. Recurrent Ameloblastoma Of The Maxillo-Facial Region. Clinical Features And Treatment. J Maxillofac Surg 1986;14:153-8

Abstract: Purpose: The aim of the study was to investigate the effect of circuit training on sleep and cognition in collegiate with poor sleep quality. Methods: The present study was conducted among 30 subjects having poor sleep quality, who were randomly allocated via lottery method to either a circuit training group or a control group i.e., a treadmill running group. The intervention was given for 3 weeks, with 3 sessions of 30 minutes per week each. Subjects were assessed for poor sleep and cognition at the beginning and end of the 3rd week....

Keywords: Circuit Training, Sleep, Poor Sleep Quality

...

Abstract: We report the case of a 23-year-old patient presenting with spinal cord compression evolving over 4 months, with persistent back pain refractory to treatment, hypoesthesia at the D10 level, and paraparesis 4/5 without
sphincter disturbances. Anatomical imaging revealed epidural lipomatosis. No predisposing factors were found. Surgical treatment was decided upon. A T10-T11 laminectomy with excision of the intradural lipoma was performed......

Keywords: Intradural extramedullary lipoma, spinal cord compression, surgical treatment, epidural
lipomatosis, neurological symptoms, idiopathic lipomatosis, obesity

...

Abstract: Cavernomas, also known as cavernous angiomas, are small vascular malformations in the brain or spinal cord that resemble a blackberry. They consist of small blood-filled cavities and their growth typically occurs through recurrent microbleeding. Diagnostic imaging, particularly MRI, allows for reliable diagnosis and monitoring, while intraoperative ultrasound could facilitate surgical procedures and consequently improve patient prognosis. We report the case of a 35-year-old patient presenting with drug-resistant generalized tonic- clonic seizures. Surgical excision of the lesion often leads to better seizure control in such patients.

Keywords: Cavernoma, Familial cavernomatosis, Epilepsy, Cerebral MRI

[1] Cave´-Riant F, Denier C, Labauge P, Et Al. Spectrum And Expression Analysis Of Krit1 Mutations In 121 Consecutive And Unrelated Patients With Cerebral Cavernous Malformations. Eur J Hum Genet 2002;10:733–40.
[2] Chin D, Harper C. Angiographically Occult Cerebral Vascular Malformations With Abnormal Computed Tomography. Surg Neurol 1983;20:138–42.
[3] Dubovsky J, Zabramski Jm, Kurth J, Et Al. A Gene Responsible For Cavernous Malformations Of The Brain Maps To Chromosome 7q. Hum Mol Genet 1995;4:453–8.
[4] Craig Hd, Gu¨Nel M, Cepeda O, Et Al. Multilocus Linkage Identifies Two New Loci For A Mendelian Form Of Stroke, Cerebral Cavernous Malformation, At 7p15-13 And 3q25.2-27. Hum Mol Genet 1998;7:1851–8.
[5] Denier C, Labauge P, Bergametti F, Et Al. Genotype-Phenotype Correlations In Cerebral Cavernous Malformations Patients. Ann Neurol 2006;60:550–6.

Abstract: Background: Cervical cancer is a cancer of the cervix, the fourth deadliest cancer in women. Diagnosed in more than 90% of cervical cancers, Human papilloma virus (HPV) is currently the most common pathogen responsible for female cancers. Numerous molecular genetic studies have provided strong evidence that HPV is an oncogenic virus. HPV was found to inactivating some of the mechanisms which regulating the cellular mitotic cycle. Due to this mitotic insult, the virus takes an advantage to launches a cascade of uncontrolled genetic events that may lead to malignant transformation of the host cell......

Keywords: Cervical cancer, cervical intraepithelial neoplasia (CIN), HPV, genotypes, DNA, PCR.

[1] Baseman Jg, Koutsky La. The Epidemiology Of Human Papillomavirus Infections. J Clin Virol. 2005; 32:S16–24.
[2] Bosch Fx, Lorincz A, Munoz N, Meijer Cj, Shah Kv. The Causal Relation Between Hpv And Cervical Cancer. J Clin Pathol 2002;55:244–65.
[3] Woodman Cb, Collins Si, Young Ls. The Natural History Of Cervical Human Papilloma Virus Infection: Unresolved Issues. Nat Rev Cancer 2007;7:11–22.
[4] The World Health Organization (Who). Comprehensive Cervix Cancer Prevention And Control: A Healthier Future For Girls And Women. Geneva, Switzerland: The World Health Organization (Who); 2013
[5] Cobo F, Concha A, Ortiz M. Human Papillomavirus Genotype Distribution In Females With Abnormal Cervical Cytology; A Correlation With Histological Study. Open Virol J 2009;3: 60–6.

Abstract: Background: Infections are one of the most common causes of seizures. Central nervous system infections can cause subsequent seizures. Parenchymal infections (viral encephalitis, bacterial meningoencephalitis, brain abscess) are particularly epileptogenic.The objective of our study was to determine and analyse infectious causes of late onset epilepsy in the Algerian population. Materials and Methods: The study population includes all Algerian patients whose age of onset of the first seizure is 25 years or more, recruited during the period from January 2008 to December 2016 at ALI AIT IDIR Hospital in Algiers........

Keywords: Late onset epilepsy, Infectious pathology, Encephalitis, Meningo-encephalitis, Cerebral abscess, Algerian population.

[1]. Weber M. Epilepsie De L'adulte : Etiologie, Diagnostic, Evolution, Pronostic, Traitement. Rev Prat. 1998, Vol. 48 : 1249-55.
[2]. Hauser WA, Annegers JF, Kurland LT. Incidence Of Epilepsy And Unprovoked Seizures In Rochester, Minnesota: 1935-1984. Epilepsia. 1993, Vol. 34(3) :453-68.
[3]. Annegers JF, Dubinsky S, Coan SP, Et Al. The Incidence Of Epilepsy And Unprovoked Seizures In Multiethnic, Urban Health Maintenance Organizations. Epilepsia. 1999, Vol. 40(4) :502–506.
[4]. Gaches J, Malon S. Herpes Simplex Encephalitis In Neuro-Surgery. Electro-Encephalographic Contribution To Early Diagnosis (Author's Transl). Sem Hop. 1982. Vol. 25; 58(12):748-53.
[5]. Persidsky, Y., & Poluektova, L. Immune Privilege And HIV-1 Persistence In The CNS. Immunological Reviews. 2006, Vol. 213(1), 180–194.

Abstract: Background: 10% of patients with Alzheimer's disease have epilepsy. Frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP - 17q) initially described in 1994 has been repeatedly associated with the presence of epilepsy. A degenerative dementia process occurring after the age of 30 is frequent in trisomy 21 and associated with neuropathological changes of the Alzheimer type, it is readily accompanied by epileptic seizures. In Huntington's disease, clinical semiology includes a choreo-athetotic syndrome, myoclonus and epileptic seizures.The objective of our study was to determine and analyse degenerative causes of late onset epilepsy in the Algerian population.......

Keywords: Late onset epilepsy, Degenerative pathology, Alzheimer's disease, Algerian population.

[1]. Hauser Wa, Annegers Jf, Kurland Lt. Incidence Of Epilepsy And Unprovoked Seizures In Rochester, Minnesota: 1935-1984. Epilepsia. 1993, Vol. 34(3) :453-68.
[2]. Annegers Jf, Dubinsky S, Coan Sp, Et Al. The Incidence Of Epilepsy And Unprovoked Seizures In Multiethnic, Urban Health Maintenance Organizations. Epilepsia. 1999, Vol. 40(4) :502–506.
[3]. Olafsson E, Ludvigsson P, Gudmundsson G, Hesdorffer D, Kjartansson O,Hauser Wa Incidence Of Unprovoked Seizures And Epilepsy In Iceland And Assessment Of The Epilepsy Syndrome Classification: A Prospective Study. Lancet Neurol. 2005, Vol. 4(10):627-34.
[4]. Gordon Eb, Sim M. The E.E.G. In Presenile Dementia. J Neurol Neurosurg Psychiatry. 1967, Vol. 30(3):285-91.
[5]. Soininen H, Partanen J, Laulumaa V, Pääkkönen A, Helkala El, Riekkinen Pj. Serial Eeg In Alzheimer's Disease: 3 Year Follow-Up And Clinical Outcome. Electroencephalogr Clin Neurophysiol. 1991.

Abstract: Mesentric cyst being one of the rare forms of abdominal cyst are usually asymptomatic and occur at a mean age of 25 years. Ultrasonography of the abdomen helps in the diagnosis and complete excision is the treatment of choice. This case report discusses a case of a large mesenteric cyst that was successfully managed by laparotomy and complete excision of the cyst.

Keywords: Mesenteric cyst, Enterogenous, Chylolymphatic, Enucleation.

[1] Ferreira Mav, Monteiro C, Monteiro C Et Al. A Large Mesenteric Cyst. Int J Case Rep Images. 2018;9:100974z01mf2018.
[2] Asgharnia M, Rahbar T, Dalil Heirati Sf. Mesenteric Cysts: A Rare Case. Clin J Obstet Gynecol. 2019;2: 067-070.
[3] Casarotto A, Cerofolini A, Denitto F Et Al. Cisti Mesenteriale: Case Report E Revisione Della Letteratura [Mesenteric Cyst: Case Report And Review Of The Literature].2010 May;31(5):239-42.
[4] Abiyere Oh, Rosiji Ob, Osho Ai Et Al. Huge Mesenteric Cyst :Case Report. Int J Surg Res Pract 8:128.
[5] Blooq Ay, Hussain S S, Elmy M. Giant Chylolymphatic Mesenteric Cyst And Its Successful Enucleation : A Case Report. International Journal Of Surgery Case Reports.2014;5(8):469-470.
[6] Kurtz Rj, Heimann Tm, Holt J Et Al. Mesenteric And Retroperitoneal Cysts. Ann Surg. 1986;203(1):109-112.

Abstract: Introduction : Congenital diaphragmatic hernia is a rare developmental defect of diaphragm Most common in childhood and rare in adult. Bochdalek hernia is the most common type Case report : A 27 years old female came to casualty with complaints of vomiting for 3 days, sudden in onset, non projectile, bilious. History of left upper abdominal pain for 3 days. History of breathlessness for 3 days. History of decreased food intake present. No history of trauma. Discussion : Congenital diaphragmatic hernia most commonly occurs on the left side of diaphragm than right. Most common organs to herniate are stomach, ileum, colon, spleen, pancreas, liver (on right side). Complete eventration occurs on left side (1) and rare on right side (2) Conclusion : Surgery is indicated for both symptomatic (2) and asymptomatic patients (3,4,5)with primary closure of defect.

[1] T. V. Thomas, "Congenital Eventration Of The Diaphragm," The Annals Of Thoracic Surgery, Vol. 10, No. 2, Pp. 180–192, 1970.
[2] M. Al-Emadi, H. Ismail, M. A. Nada, And H. Al-Jaber, "Laparoscopic Repair Of Bochdalek Hernia In An Adult," Surgical Laparoscopy And Endoscopy, Vol. 9, No. 6, Pp. 423–425, 1999.
[3] B. K. P. Goh, M. C. C. Teo, S.-P. Chng, And K.-C. Soo, "Rightsided Bochdalek's Hernia In An Adult," American Journal Of Surgery, Vol. 194, No. 3, Pp. 390–391, 2007
[4] M. Swain, A. Klaus, S. R. Achem, And R. A. Hinder, "Congenital Diaphragmatic Hernia In Adults," Semin
[5] G. D. Rice, C. J. O'boyle, D. I. Watson, And P. G. Devitt, "Laparoscopic Repair Of Bochdalek Hernia In An Adult," Anz Journal Of Surgery, Vol. 71, No. 7, Pp. 443–445, 2001

Abstract: Background: Acute lower respiratory tract infections (ALRIs) are the substantial cause of morbidity and mortality in children, especially in developing countries. Different factors were identified for the increased risk of LRTIs in children. Some of them include low birth weight, malnutrition, lack of breastfeeding, maternal literacy, smoking, low socio-demographic status etc. It is therefore crucial to identify the potential risk factors contributing to LRTI in children to suggest appropriate prevention strategies. So, a cross-sectional study was done to assess the risk factors associated with these Lower Respiratory Tract Infections........

Keywords: Pneumonia, Respiratory tract infections, Breast feeding, Immunization,

[1] Pham Ht, Nguyen Ptt, Tran St, Phung Ttb. Clinical And Pathogenic Characteristics Of Lower Respiratory Tract Infection Treated At The Vietnam National Children's Hospital. Can J Infect Dis Med Microbiol. 2020;2020:7931950.
[2] Agrawal R. Pneumonia. In: Iap Textbook Of Pediatrics. 5th Edition. New Delhi: Jaypee Brothers Medical Publishers (P) Ltd.; 2013.
[3] Rudan I, Boschi-Pinto C, Biloglav Z, Mulholland K, Campbell H. Epidemiology And Etiology Of Childhood Pneumonia. Bull World Health Organ. 2008 May;86(5):408–16.
[4] Boloursaz Mr, Lotfian F, Aghahosseini F, Cheraghvandi A, Khalilzadeh S, Farjah A, Et Al. Epidemiology Of Lower Respiratory Tract Infections In Children. J Compr Ped [Internet]. 2013 Mar 2 [Cited 2023 Nov 25];4(2):93–8. Available From: Https://Brieflands.Com/Articles/Jcp-19765.Html
[5] S. S, Patel S. A Study On Distribution Pattern Of Lower Respiratory Tract Infections In Children Under 5 Years In A Tertiary Care Centre. Int J Contemp Pediatr [Internet]. 2018 Feb 22 [Cited 2023 Nov 25];5(2):456. Available From:
Http://Www.Ijpediatrics.Com/Index.Php/Ijcp/Article/View/1371

Abstract: Introduction: Congenital cyanogenic heart disease (CCHD) accounts for 10% of all heart malformations, with Tetralogy of Fallot (TOF) representing 82.7%, characterized by a right-to-left shunt. Anesthesia before surgical correction of the shunt carries significant risks. We report the anesthetic management of uncorrected cyanogenic heart disease in a 4-year-old girl undergoing thoracic surgery......

Keywords: congenital heart diseases, anesthesia, pulmonary arterial hypertension crisis

[1] Brown Ml, Dinardo Ja, Nasr Vg. Anesthesia In Pediatric Patients With Congenital Heart Disease Undergoing Non-Cardiac Surgery: Defining The Risk. Journal Of Cardiothoracic And Vascular Anesthesia. 2020; 34:470-8.
[2] White Mc, Peyton Jm. Anesthetic Management Of Children With Congenital Heart Disease For Non-Cardiac Surgery. Continuing Education In Anaesthesia, Critical Care & Pain. 2012; 12:17-22.
[3] Miller-Hance Wc. Chapter 23: Anesthesia For Non-Cardiac Surgery In Children With Congenital Heart Disease. In: Cote Cj, Lerman J, Anderson Bj, Eds. A Practice Of Anesthesia For Infants And Children. 6th Ed. Elsevier; 2019:534-59.
[4] Beerman Lb, Md, Children's Hospital Of Pittsburgh Of Upmc, University Of Pittsburgh School Of Medicine, December 2020, High Mortality.
[5] European Society Of Cardiology, Vahanian A, Baumgartner H, Bax J, Butchart E, Dion R, Et Al. Guidelines On The Management Of Valvular Heart Disease. The Task Force.

Abstract: Introduction: Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare autosomal recessive tubular disease that eventually progresses to renal failure, depending on the extent of nephrocalcinosis. Its fundamental pathogenesis involves impaired tubular reabsorption of magnesium and calcium in the thick ascending limb of the loop of Henle due to a genetic defect of paracellin-1 (a tight junction protein expressed at the thick ascending limb). Mutations in the claudin-16 (CLDN16) gene, formerly known as the paracellin-1 (.......

Keywords: hypomagnesemia with hypercalciuria and nephrocalcinosis, Paracellin-1, CLDN16

[1] Michelis Mf, Drash Al, Linarelli Lg, De Rubertis Fr, Davis Bb. Decreased Bicarbonate Threshold And Renal Magnesium Wasting In A Sibship With Distal Renal Tubular Acidosis: Evaluation Of The Pathophysiological Role Of Parathyroid Hormone. Metabolism. 1972;21:905-20.
[2] Benigno V, Canonica Cs, Bettinelli A, Von Vigier Ro, Truttmann Ac, Bianchetti Mg. Hypomagnesaemia-Hypercalciuria-Nephrocalcinosis: A Report Of Nine Cases And A Review. Nephrol Dial Transplant. 2000;15:605–10.
[3] Lodha R, Hari P, Bagga A. Syndrome Of Renal Magnesium Wasting And Nephrocalcinosis. Indian Pediatr. 1999;36:1046–8.
[4] Weber S, Hoffmann K, Jeck N, Et Al. Familial Hypomagnesaemia With Hypercalciuria And Nephrocalcinosis Maps To Chromosome 3q27 And Is Associated With Mutations In The Pcln-1 Gene. Eur J Hum Genet. 2000;8:414–22.
[5] Weber S, Schneider L, Peters M, Et Al. Novel Paracellin-1 Mutations In 25 Families With Familial Hypomagnesemia With Hypercalciuria And Nephrocalcinosis. J Am Soc Nephrol. 2001;12:1872–81.

Abstract: Duplications of alimentary tract are found in 1 in 10,000 births. They may be either cystic or tubular. Approximately 80% cases present before age of 2 years [1]. Although they can be detected in any part of the digestive tract from the oral cavity to the anus, they are most frequently identified in the small intestine.[2] They usually present with complaints like pain, abdominal distention and vomiting [3]. Features like obstruction, bleeding per rectum, perforation......

[1] Holcomb 3rd Gw, Gheissari A, O'neill Jr Ja, Shorter Na, Bishop Hc. Surgical Management Of Alimentary Tract Duplications. Annals Of Surgery. 1989 Feb;209(2):167.
[2] Ildstad St, Tollerud Dj, Weiss Rg, Ryan Dp, Mcgowan Ma, Martin Lw. Duplications Of The Alimentary Tract. Clinical Characteristics, Preferred Treatment, And Associated Malformations. Annals Of Surgery. 1988 Aug;208(2):184.
[3] Wrenn El, Hollabaugh Rs, Ashcraft Kw. Pediatric Surgery.
[4] Karnak I, Ocal T, Senocak Me, Tanyel Fc, Büyükpamukçu N. Alimentary Tract Duplications In Children: Report Of 26 Years' Experience. The Turkish Journal Of Pediatrics. 2000 Apr 1;42(2):118-25.
[5] Ildstad St, Tollerud Dj, Weiss Rg, Ryan Dp, Mcgowan Ma, Martin Lw. Duplications Of The Alimentary Tract. Clinical Characteristics, Preferred Treatment, And Associated Malformations. Annals Of Surgery. 1988 Aug;208(2):184

Abstract: Pupillary block is a frequent complication of cataract surgery with anterior chamber intraocular (ACIOL) implantation. This study is to report pupillary block after complicated Cataract surgery other than ACIOL. In our case series, 2 cases have pupillary block after complicated cataract surgery (Retropupillary Iris Claw lens, Posterior capsular rent) and in one case, pupillary block after YAG Capsulotomy. In all 3 cases, pupillary block is relieved by Nd-YAG (Neodymium doped Yttrium Aluminum Garnet) Peripheral Iridotomy. All patients got visual acuity improved to 20/20 with normal intraocular pressure. None of the patients were on anti-glaucoma medications. So, early diagnosis and treatment of pseudophakic pupillary block can prevent the permanent vision loss.

Keywords: Pupillary block Glaucoma, Cataract surgery, Nd-Yag Capsulotomy, YAG peripheral iridotomy

[1] Gaton Dd, Mimouni K, Lusky M, Ehrlich R, Weinberger D. Pupillary Block Following Posterior Chamber Intraocular Lens Implantation In Adults. Br J Ophthalmol. 2003 Sep;87(9):1109-11.
[2] Cohen Js, Osher Rh, Weber P, Et Al. Complications Of Extracapsular Cataract Surgery. The Indications And Risks Of Peripheral Iridectomy. Ophthalmology 1984;91:826–30.
[3] Schulze Rr, Copeland Jr. Posterior Chamber Intraocular Lens Implantation Without Peripheral Iridectomy: A Preliminary Report. Ophthalmic Surg 1982;13:567.
[4] Vajpayee Rb, Angra Sk, Titiyal Js, Et Al. Pseudophakic Pupillary-Block Glaucoma In Children. Am J Ophthalmol 1991;111:715–8.
[5] Naveh N, Wysenbeek Y, Solomon A, Et Al. Anterior Capsule Adherence To Iris Leading To Pseudophakic Pupillary Block. Ophthalmic Surg 1991;22:350–2.