iosr-JDMS   Volume-23 ~ Issue-5 ~ May 2024

Abstract: Background. Adrenalin was supposed to have an anti-inflammatory effect; hence adrenalin concentration in blood serum might be lower in inflammatory diseases. Coffee contains caffeine that is thought to have the potency to increase adrenalin secretion in inflammatory diseases. This study aimed to analyze the effect of coffee consumption on adrenalin blood levels in periodontitis rat model. Materials and Methods. This in vivo experimental study used the post-test-only control group design. Wistar male rats (Rattus novergicus) were divided into four groups (four rats/group) i.e. 1) Periodontitis (no coffee), 2) periodontitis + coffee, 3) Coffee (no periodontitis), 4) Control (no coffee, no periodontitis).........

Key Words: Caffeine; Elisa; Inflammatory disease; Phorpyromonas gingivalis; Robusta coffee

[1]. Tintinger Gr, Theron Aj, Anderson R, Ker Ja. The Anti-Inflammatory Interactions Of Epinephrine With Human Neutrophils In Vitro Are Achieved By Cyclic Amp-Mediated Accelerated Resequestration Of Cytosolic Calcium. Biochemical Pharmacology 2001;61(10):1319–1328. [2]. Engdahl Rk, Opperman K, Yerrum S, Monroy A, Daly J. Epinephrine Regulation Of Pro-Inflammatory And Anti-Inflammatory Macrophage Cytokine Expression. Journal Of The American College Of Surgeons 2007;205(3) Supplement:S35. [3]. Jenei-Lanzl Z, Capellino S, Kees F, Fleck M, Lowin T, Straub R. H. Anti-Inflammatory Effects Of Cell-Based Therapy With Tyrosine Hydroxylase-Positive Catecholaminergic Cells In Experimental Arthritis. Annals Of The Rheumatic Diseases 2015;74(2):444–451. [4]. Chen S, Liu Gl, Li Mm, Liu, Liu H. Effects Of Epinephrine On Inflammation-Related Gene Expressions In Cultured Rat Cardiomyocytes. Translational Perioperative And Pain Medicine 2017;2(1):13–19. [5]. Linden Gj, Lyons A, Scannapieco Fa. Periodontal Systemic Associations: Review Of The Evidence. Journal Of Clinical Periodontology 2013;40 (Suppl. 14):S8–S19.

Abstract: Background: Cleft lip and palate (CLP) is the most common congenital anomalies. CLP patients need multiple surgeries to correct these deformities to achieve function and esthetic needs. As a result of these surgeries, CLP individuals suffer from midface hypoplasia. The correction of maxillary hypoplasia is by conventional orthognathic or maxillary distraction osteogenesis. Materials and Methods: This review of literature is based on searches through main databases included Pubmed, Sciencedirect and Scoupus. Also, through grey literature EKB, Google Scholar to expand our search. We used searching keywords include cleft lip and palate, conventional orthognathic surgery, maxillary distraction osteogenesis connected with Boolean operators OR, AND.........

Keywords: cleft lip and palate, cleft non syndromic patients, conventional osteotomy le fort I, maxillary distraction osteogenesis, stability and relapse, speech, velopharyngeal incompetence, soft tissue changes, morbidity and blood supply.

[1] Mossey Pa, Modell B. Epidemiology Of Oral Clefts: An International Perspective, In Cleft Lip And Palate. Front Oral Biology. 2012;16(1):1–18.
[2] Stuppia L, Capogreco M, Marzo G, La Rovere D, Antonucci I, Gatta V, Et Al. Genetics Of Syndromic And Nonsyndromic Cleft Lip And Palate. Journal Of Craniofacial Surgery. 2011;22(5):1722–6.
[3] Dixon Mj, Marazita Ml, Beaty Th, Murray Jc. Cleft Lip And Palate: Understanding Genetic And Environmental Influences. Nat Rev Genet. 2011;12(3):167–78.
[4] Parker Se, Mai Ct, Canfield Ma, Rickard R, Wang Y, Meyer Re, Et Al. Updated National Birth Prevalence Estimates For Selected Birth Defects In The United States, 2004-2006. Birth Defects Res A Clin Mol Teratol. 2010;88(12):1008–16.
[5] Frederick R, Hogan Ac, Seabolt N, Stocks Rms. An Ideal Multidisciplinary Cleft Lip And Cleft Palate Care Team. Oral Dis. 2022 Jul 1;28(5):1412–7.

Abstract: Background: Dyke-Davidoff-Masson syndrome is a rare condition of unknown frequency resulting from brain injury due to a multitude of causes; especially in early life. Characteristics include cerebral hemiatrophy/ hypoplasia, contralateral hemiparesis, seizures, and compensatory osseous hypertrophy. Due to Its rarity , it may be misdiagnosed or under-reported by majority of clinicians.[1-3]. Case presentation: We present a case of 8 yr old girl who presented to us with breakthrough seizures Conclusions: Due to its rarity, Dyke-Davidoff-Masson syndrome may easily be missed by the majority of treating clinicians. Knowledge of its features on imaging enables timely and accurate diagnosis – allowing appropriate management.

Keywords: Dyke-Davidoff-Masson syndrome, Computed tomography (CT)

[1] Verma R, Sahu R. Dyke-Davidoff-Masson Syndrome. Bmj Case Reports. 2012.Https://Doi.Org/10.1136/Bcr-2012-006729.
[2] Piro E, Piccione M, Marrone G, Giuffre M, Corsello G. Dyke-Davidoff-Masson Syndrome: Case Report Of Fetal Unilateral Ventriculomegaly And Hypoplastic Left Middle Cerebral Artery. Ital J Pediatr. 2013;39:32.
[3] Roy U, Panwar A, Mukherjee A, Biswas D. Adult Presentation Of Dyke Davidoff-Masson Syndrome: A Case Report. Case Rep Neurol. 2016;8:20–6.
[4] Dyke Cg, Davidoff Lm, Masson Cb. Cerebral Hemiatrophy And Homolateral Hypertrophy Of The Skull And Sinuses. Surg Gynecol Obstet. 1933;57:588–600.
[5] Gokce E, Beyhan M, Sade R. Radiological Imaging Findings Of Dyke-Davidoff Masson Syndrome. Acta Neurol Belg. 2017;117(4):885–93.

Abstract: Background: Due to decreased physical activity, muscle flexibility in modern housewives is usually reduced. The habit of toileting seems to affect the flexibility for most of the population. Materials and Methods:The subjects included 30 subjects were randomly allocated in two groups :Group A [N = 50 ]shank muscle training and Group B [N=15]Control group .All the subjects were given informed consent form will be taken from each of the subjects to participation. Instruction are given to the subjects about technique performed. The subjects was included in the study through self made screening score and measured using ankle dorsiflexion wall test (using inch tape).........

Key Words: Ankle flexibility, Inch tape,VISAA scale,ankle dorsiflexion test.

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Abstract: The occurrence of CNS tumours during pregnancy is rare and it poses a serious risk for both mother and baby. The incidence of CNS tumours complicating pregnancy is 1/11460.

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Abstract: Isolated sixth nerve( Abducens Nerve) palsy is a type of mononeuropathy resulting in the weakness of lateral rectus muscle. Neoplasia, vascular disease, and trauma are among the most common causes. Microvascular ischemia related to hypertension and / or diabetes is a commonly identified cause of sixth nerve palsy in older adults.

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Abstract: Background Calcaneal spurs are bony outgrowths that develop on the calcaneus (heel bone) and are frequently associated with heel pain conditions such as plantar fasciitis. Despite their clinical significance, there is limited understanding of the prevalence, distribution, and morphological characteristics of calcaneal spurs in specific populations. Addressing this knowledge gap is crucial for informing diagnostic and treatment approaches tailored to individual patient needs. Therefore, this study aimed to investigate the prevalence, distribution, and morphological features of calcaneal spurs in a sample population from western Gujarat. This study aimed to investigate the prevalence, distribution, and morphological features of calcaneal spurs in a sample population from western Gujarat........

Keywords: Morphometric Analysis, Calcaneal Enthesophytes, Human Calcanea, Western Gujarat

[1]. Perumal A, Anand A. Morphometric Study Of Spur Formation In Dry. 2013;05(07):92–6.
[2]. Kullar J, Kullar K, Randhawa G. A Study Of Calcaneal Enthesophytes (Spurs) In Indian Population. Int J Appl Basic Med Res. 2014;4(3):13. [3]. Kose N. , Gokturk E. , Turgut A. , Seber S. , Hazer B. The Relationship Between Pes Planus And Calcaneal Spur To Plantar Heel Pain. Acta Orthopaedica Et Traumatologica Turcica. 2006; 32(4): 322-324.
[4]. Velagala Vr, Velagala Nr, Kumar T, Singh A, Mehendale Am. Calcaneal Spurs: A Potentially Debilitating Disorder. Cureus. 2022 Aug 28;14(8):E28497. Doi: 10.7759/Cureus.28497. Pmid: 36185871; Pmcid: Pmc9514376.
[5]. Lourdes, R. K., & Ram, G. G. (2016). Incidence Of Calcaneal Spur In Indian Population With Heel Pain. International Journal Of Research In Orthopaedics, 2(3), 173.

Abstract: The management of chronic inflammatory bowel diseases requires a therapeutic arsenal. Among the treatments offered, we have biological therapies including ustekinumab, a monoclonal antibody, which acts by inhibiting interleukins 12 and 23, thus reducing the inflammatory activity observed in this type of disease. We report the case of a patient suffering from Crohn's disease who developed unexpected nail and skin involvement such as trachyonychia and erythematous axillary plaques following initiation of treatment with ustekinumab. Despite its rarity, this case highlights the importance of vigilance for adverse reactions and the need for continued monitoring as well as a thorough understanding of the mechanisms of biologic drugs in the management of chronic inflammatory diseases.

Key Word: Ustekinumab; nail damage; paradoxical psoriasis; anti IL 12/23; Crohn's disease

[1]. Higashiyama M, Hokaria R. New And Emerging Treatments For Inflammatory Bowel Disease. Digestion. 2023;104(1):74-81. Doi: 10.1159/000527422.
[2]. Jullien D, Staumont-Salle D; Groupe De Recherche Sur Le Psoriasis De La Société Française De Dermatologie. Ustékinumab [Ustekinumab]. Ann Dermatol Venereol. 2019 Jun-Jul;146(6-7):497-502. French. Doi: 10.1016
[3]. Naik Pp. Adverse Effects Of Anti-Interleukin-23 Agents Employed In Patients With Psoriasis: A Systematic Review. Dermatology. 2022;238(5):886-896. Doi: 10.1159/000524199.
[4]. Klimko A, Olteanu Ao, Tieranu I, Orzan Oa, Toma Cv, Ionescu Em, Preda Cm, Tieranu Cg. Paradoxical Psoriasis Induced By Ustekinumab: A Comprehensive Review And Case Report. Medicina (Kaunas). 2024 Jan 6;60(1):106. Doi: 10.3390
[5]. Deepak P, Loftus Ev Jr. Ustekinumab In Treatment Of Crohn's Disease: Design, Development, And Potential Place In Therapy. Drug Des Devel Ther. 2016 Nov 11;10:3685-3698. Doi: 10.2147

Abstract: The utility arch is a crucial and versatile tool that assists in both interceptive and comprehensive orthodontic treatments. It can be used during different stages of orthodontic treatment, whether it is in mixed or permanent dentition. Originally developed in 1977 by C.J. Burstone, the utility arch was created to align the curve of Spee in the mandible utilizing biomechanical principles. Over time, the utility arch was further adapted and refined by Ricketts and became an essential key component of Bioprogressive Therapy, a modern orthodontic treatment approach. The utility arch is particularly useful for intruding upper and lower incisors, as well as protruding and retruding anterior teeth.....

Keyword: Utility arch, Intrusion arch, Class II div 2

[1] Burstone Cd. Deep Overbite Correction By Intrusion. Am J Orthod 1977;72:1-22.
[2] Mcnamara Ja. Utility Arches. Am J Orthod 1986;20:452-56.6
[3] Ricketts Rm. Dr. Robert M. Ricketts On Early Treatment (Part 2). J Clin Orthod 1979;13:115-27.
[4] Strang R. Class Ii Division 2 Malocclusion. Angle Orthodontist 1958;28(4):210–214. 5.
[5] Rakesh A, Reddy V, Reddy D. Utility Arches In Orthodontics – Case Reports. Ann Essences Dent 2011;3(1):60–64.

Abstract: Jejunal diverticulosis (JD), a rare condition characterized by outpouchings of the small intestine, often presents a diagnostic challenge. While typically asymptomatic, JD can lead to complications like intestinal obstruction and diverticulitis. This case report describes a 75-year-old male who presented with acute abdominal pain, vomiting, and signs of intestinal obstruction. Imaging studies suggested a small bowel obstruction with a possible right para duodenal hernia. However, exploratory laparotomy revealed a more complex picture: multiple inflamed jejunal diverticula with adhesions and impending perforation, consistent with jejunal diverticulitis.....

Keywords: Jejunal diverticulosis, small bowel obstruction, peritonitis, case report

[1] Banerjee, Divya & Chauhan, Himesh. (2024). Jejunal Diverticular Perforation In An Acute Abdomen: A Case Report. Indian Journal Of Case Reports. 10. 44-46. 10.32677/Ijcr.V10i2.4363.
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[3] Tenreiro T, Moreira H, Silvia S, Marcques R, Monterio A, Gasper J, Et Al. Jejunoileal Diverticulosis, A Rare Cause Of Ileal Perforation-Case Report. Ann Med Surg (Lond) 2016;6:56-9.
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Abstract: Background: Genital fistula is a psycho-sexual problem characterized by disruption in sexual relationships due to continuous leakage of urine and/or faeces. We aimed to report sexual activity and associated factors among women with genital fistula in our environment. Methodology: It was a descriptive cross-sectional study carried out in a fistula hospital in Southern Nigeria among sixty women with genital fistula admitted for surgical repair. Informed consent was obtained. Information was obtained using interviewer-administered questionnaires and entered into an electronic database. Data was analysed using descriptive statistics.....

Keywords: Genital Fistula; Obstetric fistula; Sexual Activity; Vesicovaginal Fistula

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Abstract: Aim: To assess Knowledge and Awareness of Diabetes amongst people living in southern Rajasthan. Background: Awareness of various aspects of Diabetes is essential for the prevention, management and control of the disease. However, several studies have consistently shown that awareness of diabetes in the general population is low. Diabetes is a common chronic disease with increasing prevalence worldwide; it leads to devastating human, social....

[1] Standl E, Khunti K, Hansen TB, Schnell O. The Global Epidemics Of Diabetes In The 21st Century: Current Situation And Perspectives. Eur J Prev Cardiol. (2019) 26: Page No 7–14. Doi: 10.1177/2047487319881021
[2] Saeedi P, Petersohn I, Salpea P, Malanda B, Karuranga S, Unwin N, Et Al. Global And Regional Diabetes Prevalence Estimates For 2019 And Projections For 2030 And 2045: Results From The International Diabetes Federation Diabetes Atlas, 9th Edition. Diabetes Res Clin Pract. (2019) 157:107843. Doi: 10.1016/J.Diabres.2019.107843
[3] Cho NH, Shaw JE, Karuranga S, Huang Y, Da Rocha Fernandes JD, Ohlrogge AW, Et Al. IDF Diabetes Atlas: Global Estimates Of Diabetes Prevalence For 2017 And Projections For 2045. Diabetes Res Clin Pract. (2018) 138:271– 81. Doi: 10.1016/J.Diabres.2018.02.023
[4] Wu Y, Ding Y, Tanaka Y, Zhang W. Risk Factors Contributing To Type 2 Diabetes And Recent Advances In The Treatment And Prevention. Int J Med Sci 2014;11:1185-200.
[5] Cunningham-Myrie C, Younger-Coleman N, Tulloch-Reid M, Mcfarlane S, Francis D, Ferguson T, Et Al. Diabetes Mellitus In Jamaica: Sex Differences In Burden, Risk Factors, Awareness, Treatment And Control In A Developing Country. Trop Med Int Health 2013;18:1365-78.

Abstract: Cerebellar ataxia can be antibody- mediated, and this can occur in the setting of paraneoplastic syndrome or in the absence of an ongoing malignancy. Interestingly, the detection of specific types of autoantibodies has been found to be statistically linked to different etiologies. Anti-Yo, -Zic, -CARPVIII, -Tr, -Ri, -Hu, -Ma, -CRMP-5, -ANNA-3, -PCA-2, -VGCC, and -mGluR antibodies were more commonly associated with paraneoplastic processes, while anti-GAD, -thyroid, and -gliadin were usually non-paraneoplastic. We present a case of ataxia due to both anti-glutamic acid decarboxylase (GAD) antibodies and anti- ZIC4 (Zinc-finger protein 4) not associated with malignancy.

Keywords: Cerebellar ataxia, Anti GAD, Anti ZIC4

[1] Ariño H, Gresa-Arribas N, Blanco Y, Martínez-Hernández E, Sabater L, Petit-Pedro Lm, Rouco I, Bataller L, Dalmau J, Saiz A, Graus F. Cerebellar Ataxia And Glutamic Acid Decarboxylase Antibodies: Immunologic Profile And Long-Term Effect Of Immunotherapy.Jamaneurol.2014;71:1009–1016.
[2] Honnoratj,Saiza,Giomettob,Vincenta,Brieval,Andresc,Maestrej,Fabienn,Vighetto A, Casamitjana R, Thivolet C, Tavolato B, Antoine Jc, Trouillas P, Graus F.Cerebellar Ataxia With Anti-Glutamic Acid Decarboxylase Antibodies: Study Of 14 Patients .Arch Neurol. 2001; 58: 225–230.
[3] Philip A. Loehrer, Lars Timmermann, Anika Pehl, Corinna I. Bien , Andreas Pfestroff, And David J. Pedrosa. Rhombencephalitis Associated With Isolated Zic4-Antibodiesin Paraneoplastic Cerebellar Degeneration: A Case Report.Bmc Neurol.2020;20:208.
[4] Leypoldt F, Wandinger K-P. Paraneoplastic Neurological Syndromes: Clin Exp Immunol.2014;175:336–348.
[5] Crawford Jr, Say D. Vitamin B12 Deficiency Presenting As Acute Ataxia. Bmj Case Rep. 2013;2013 Pii: Bcr2013008840.

Abstract: Adequate Inter-arch space is necessary in case of a successful prosthesis. Reduced interarch space can further affect the stability, crown/root ratio alteration, and poor aesthetics. Rehabilitation of a distal extension in partially edentulous patient become more difficult once the patient neither accepts the treatment choice of implant placement nor for a removable prosthesis. The solution in such a vital scenario is to place a combined prosthesis. The case report describes the management of reduced inter-arch area with periodontics and prosthodontics interdisciplinary approach. It encompasses of periodontal approach to extend the space for an ideal prosthesis..

Keywords: Dental Prosthesis, Precision Attachment, Reduced inter-arch space, Combined Prosthesis, Fixed- Removable prosthesis, Crown lengthening, Alveoloplasty

[1] Misch Ce. Dental Implant Prosthetics. Mosby. 2005:165–6.
[2] Basutkar N & Alamoudi R & Alharbi R. (2020). Full Mouth Rehabilitation Of A Patient With Restorative Space Issues -A Case Report. Asian Journal Of Pharmaceutical Research And Health Care (Ajprhc). 12. 1-7. 10.18311/Ajprhc/2020/25374.
[3] Mukherji A, Rath Sk. Full-Mouth Aesthetic Rehabilitation: A Perio-Prostho Interdisciplinary Approach. J Int Clin Dent Res Organ 2015;7:155-8.
[4] Soni R, Yadav H, Priya A. Combined Prosthesis With Precision Attachment For Distal Extension Kennedy Class Ii Arch: A Case Report. Indian J. Sci. Res. 2018 Mar 1;20(2):126-8.
[5] Jain A.R., 2013. A Prosthetic Alternative Treatment For Severe Anterior Ridge Defect Using Fixed Removable Partial Denture Andrew's Bar System. W Joud., 4(4):282-285..

Abstract: Objective: The aim of this study was to evaluate the awareness about orthodontic aligners and newer treatment modalities among the dental students and perception about other treatment modalities that can be performed using the same. Methods A questionnaire-based study was conducted on 246 dental students. from December 2022 to March 2023. An original 22 question survey was prepared and distributed to the dental students studying in various dental colleges in....

Keywords: Dental students, Orthodontic Aligner therapy, Invisible orthodontics, Esthetic treatment

[1] Koroluk Ld, Jones Je, Avery Dr. Analysis Of Orthodontic Treatment By Pediatric Dentists And General Practitioners In Indiana. Asdc Jdent Child 1988;55:97-101 2.
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[4] Borda Af, Garfinkle Js, Covell Jr Da, Wang M, Doyle L, Sedgley Cm. Outcome Assessment Of Orthodontic Clear Aligner Vs Fixed Appliance Treatment In A Teenage Population With Mild Malocclusions. The Angle Orthodontist. 2020 Jul 1;90(4):485-90.
[5] Rossini G, Parrini S, Castroflorio T, Deregibus A, Debernardi Cl. Efficacy Of Orthodontic Aligners In Controlling Orthodontic Tooth Movement: A Systematic Review. The Angle Orthodontist. 2015 Sep;85(5):881-9..

Abstract: We aimed to measure and compare the golden proportion and gingival zenith position in adult volunteers in Saurastra region, Gujarat. In esthetic dentistry, anterior rehabilitation and smile designing cases thorough knowledge of golden proportion and gingival zenith position of maxillary anterior teeth merit clinical importance. Young adult's volunteers in age group between 18 to 30 years without any dental deformity were selected for the study. Inclusion criteria involved absence of periodontal diseases. Alginate impressions were made and diagnostic casts.....

Keywords: Golden proportion, Gingival zenith position, Maxillary anterior teeth, Esthetic dentistry, Digital caliper

[1] Ahmed N, Halim Msb, Ghani Za, Khan Za, Abbasi Ms, Jamayet Nb, Alam Mk. A 2d Photographic And 3d Digital Dental Model Analysis Of Golden Percentage In Maxillary Anterior Teeth. Biomed Res Inter 2021, Article Id 6674400 |
Https://Doi.Org/10.1155/2021/6674400
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[4] Sharma A. A Descriptive Study Of Some Of The Dentogingival Components Of Esthetics Of Patients At A Tertiary Care-Center In The Eastern Part Of Nepal. Inter Jour Dent 2022, Article Id 558930; Doi.Org/10.1155/2022/5589309
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Abstract: Background: The field training course for nursing specialization is considered one of the important courses that provide students with specialized practical skills, so the study aimed to reveal the problems faced by training students in the nursing specialty for the diploma stage. Materials and Methods: The researchers used the descriptive survey method through the electronic questionnaire tool. The study sample consisted of (78) students registered for the field training course in the nursing specialty during the second semester of the academic year 2023 -2024, at Ajloun University College, Al-Balqa Applied University (Jordan)......

Keywords: Nursing Specialty, Diploma Program, Training.

[1]. Al-Balqa Applied University, Regulations And Instructions. Retrieved......

Abstract: Asthma is a serious global health problem affecting all age groups whose prevalence is increasing , especially among children. Asthma imposes an unacceptable burden on health care systems, and on society through loss of productivity in the workplace and, especially for pediatric asthma, disruption to the family. Asthma is a chronic inflammatory condition of the lung airways resulting in episodic airflow obstruction . Asthma is a common......

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