iosr-JDMS   Volume-16 ~ Issue-5 ~ May-2017

Abstract: The goal of prosthodontics is rehabilitation of missing oral and extraoral structures along with restoration of the normal functions of mastication, speech, swallowing, appearance.Hemimaxillectomy patients present with abrupt alterations in the physiologic processes of the maxillae, along with increased anxiety levels due to sudden impairment in aesthetics, mastication, speech. Such patients should be rehabilitated as early as possible. This case report illustrates the rehabilitation of a patient, who had undergone maxillectomy on the left side, due to maxillary neurilemmoma..............

Keywords: Hemi maxillectomy, Obturator, Maxillary Neurilemmoma, Aramany Class II defect.

[1]. Chalian, V.A., Drane, J.B. & Standish, S.M. Maxillofacial Prosthetics. Multidisciplinary practice, The Williams & Wilkins Co., Baltimore: 1971; pp. 133-148.
[2]. Ahila SC, Anitha KV, Thulasingam C.Comparison of obturator design for acquired maxillary defect in completely edentulous patients. Indian J Dent Res 2011; 22(1): 161-163.
[3]. Beumer III, Curtis TA, Firtell DN. Maxillofacial rehabilitation. Prosthodontic and surgical considerations. St Louis, Toronto, London:The CV. Mosby Co.; 1979. p. 188‑243
[4]. Wiens JP. Acquired maxillofacial defects from motor vehicle accidents: Statistics and prosthodontic considerations. J Prosthet Dent 1990;63:172‑81
[5]. Buckner H. Construction of a denture with hollow obturator, lid, and soft acrylic lining. J Prosthet Dent 1974;31:95‑9.

Abstract: This study was conducted to evaluate the incidence and risk factors of chalazion in bundelkhand region. This is retrospective study doneFrom SEPTEMBER 2014 to DECEMBER 2016. 30,720 patients visited our opd in this duration out of which 75pts were diagnosed as chalazion and included in the study. The overall incidence of chalazion is found to be 0.24% among the patients visiting eye opd MLB Medical College Jhansi.Out of 75 pts 24(32%) were male and 51(68%) were female. Among 24 males 16(66%) were 30 yrs or less of age and 8(34%) were more than 30 yrs of age. Among 51 females 40(78%) were 30 yrs or less of age and 11(21%) were more than 30 yrs of age..............

Keywords: eyelid, chalazion, poor lid hyagine, chronic blepharitis.

[1]. Lederman C, Miller M Hardeola and chalazia 1999;20(8):283-4.
[2]. Litoff D balin MW. Ocular infection and inflammation 1992.
[3]. Aoki M. ,kawana S. Bilateral chalazia of lower lid associated with pulmonary tuberculosis, actaderm vnereol.2002;82(5):386-7
[4]. Gilchrist H ,Lee G. Management of chalazion in general practice 2009,38(5);311-314
[5]. Ben Simon GJ,HuangL,NakraT,etal.Intralesional triamcinolone acetonide injection for primary and recurrent chalazia:is it really effective? Ophthalmology.2005;112(5):913-917..

Abstract: A woman's reproductive history may affect her risk for coronary heart disease. Parity has been associated with increased coronary disease risk in some studies, while other studies have shown that nulliparous women are at increased risk (1-3). Pregnancy frequency (including frequency of spontaneous abortion (4, 5)) and age at first pregnancy (6) have also been associated with increased coronary disease risk. Although reports of associations of coronary disease risk with parity, age at menarche, or incidence of miscarriage are not all consistent (7, 8), the majority of cohort studies have shown an increased risk of coronary disease among women with high gravidity or parity (9).........

Keywords: Lipoprotein, Pregnancy, HDL Cholesterol, Primipara, Nullipara, LDL Cholesterol

[1]. Beral V. Long term effects of childbearing on health. J Epidemiol Community Health 1985;39:343-6.
[2]. Ness RB, Harris T, Cobb J, etaJ. Number of pregnancies and the subsequent risk of cardiovascular disease. N Engl J Med 1993;328:1528-33.
[3]. Talbot EO, Kuller LH, Detre K, et al. Reproductive history of women dying of sudden cardiac death: a case-controlled study. Int J Epidemiol 1989;18:589-94.
[4]. Winkelstein W, Stenchever MA, Lilienfeld AM. Occurrence of pregnancy, abortion, and artificial menopause among women with coronary artery disease: a preliminary study. J Chronic Dis 1958;7:273-86.
[5]. Bengtsson C, Rybo G, Westerberg H. Number of pregnancies, use of oral contraceptives and menopausal age in women with ischemic heart disease, compared to a population sample of women. Acta Med Scand 1973;549:75-81.

Abstract: Physicians are often facing the task of predicting the immediate and long-term outcome in stroke patients. Early predictor of mortality and poor outcome are crucial for planning the level of care and optimizing resource utilization. It is important efficiently and optimally to utilize resources. The use of early prognostic data provided by various scores in critically ill stroke patients remains unclear. The objective of the study was to determine validity of GCS for prediction of short-term mortality in acute stroke patients..........

Keywords: GCS, Prognosis, CT scan, ICH and CI, Stroke, Mortality

[1]. Allen CMC, Lueck CJ, Dennis M. Neurological disease. In: Boon NA, Colledge NR, Walker BR, Hunter JAA (eds). Davidson's Principles & Practice of Medicine. 20th ed. Churchill Livingstone, Elsevier 2006; 1145-1256.
[2]. Ropper AH, Brown RH. Adams and Victor's Principles of Neurology. 8th ed. McGraw-Hill companies 2005; 660-740.
[3]. Warlow C. Stroke, Transient ischaemic attack and intracerebral venous thrombosis. In: Donaghy M (ed). Brain's disease of the Nervous system. 11th edi. Oxford 2002; 776-856.
[4]. World Health Organization [WHO]. Geneva: WHO; 2004. World health report 2004: Changing history [online]. Accessed on April 24, 2007.
[5]. World Health Organization [WHO]. Report of the WHO Task Force on Stroke and other Cerebrovascular Disorders. Recommendations on stroke prevention, diagnosis and therapy. Stroke 1989; 20:1407-10.

Abstract: To observe the specific pattern of adverse effect due to Carbamazepine (CBZ) and to determine the clinical relevance. A random once weekly data collection was done for a period of one year. Patients of all ages and both sexes were included in the study. Informed consent was obtained. Every patient was examined clinically and their side effects were detected. The data obtained was analyzed and presented with appropriate statistical methods. Unfortunately it was observed that Carbamazepine has wide spectrum of side effects. Severity of these adverse effects ranges from minimal impairment of the CNS to death from aplastic anaemia.

Keywords: Carbamazepine, antiepileptic, ADR, side effect, aplastic anaemia.

[1]. R. S. Satoskar, Pharmacology and Pharmacotherapeutics (Mumbai: Popular Prakashan,2007)
[2]. KD Tripathi, Essentials of Medical Pharmacology (New Delhi: Jaypee Brothers Medical Publishers Pvt. Ltd.,2014)
[3]. McHugh JC, Delanty N. Epidemiology and classification of epilepsy: gender comparisons. Int Rev Neurobiol; 83, 2008, 11– 26
[4]. Hauser, W. A. and Kurland, L. T., The Epidemiology of Epilepsy in Rochester, Minnesota, 1935 Through 1967. Epilepsia, 16(1):
1– 66
[5]. Christensen, J., Kjeldsen, M. J., Andersen, H., Friis, M. L. and Sidenius, P. (2005), Gender Differences in Epilepsy. Epilepsia, 46:
956– 960.

Abstract: Cardiomyopathy is a primary disorder of the heart muscle that causes abnormal myocardial performance and is not the result of disease or dysfunction of other cardiac structures. Dilated cardiomyopathy is the most common variety of cardiomyopathy. Other types of cardiomyopathy are hypertrophic and restrictive cardiomyopathy. Dilated cardiomyopathy represents the final common pathway produced by a variety of ischaemic, toxic, metabolic and immunological mechanisms damaging the heart muscle. The incidence of DCM is reported to be 5 to 8 cases per 1,00,000 population per year..........

Keywords: FNAC, USG, HPE, Thyroid Nodule.

[1]. Richerdson. WHO report on classification of cardiomyopathy Br. Heart J. 1980; 44: 680-682
[2]. Framingham heart study nih.gov/Framingham
[3]. Braunwald and Bristow MR. Congestive heart failure: fifty years of progress. Circulation 2000; 102; 14
[4]. Hurst's The heart classification of cardiomyopathy. Chap 75: 1886-1887
[5]. Ahmad S, Rabbani M. clinical ECG and echocardiographic profile of patients with dilated cardiomyopathy. Indian J Cardiol 2005;
8: 25-29.

Abstract: There has been an increasing incidence of coronary artery disease in India and a greater Rise is expected in next few years. coronary artery disease in Indians has been found to be more severe and widespread and have been found to be associated with serious complications and increasing mortality. Thus arises the necessity of a tool which act as a risk predictor,can assess the severity and prognosis of acute coronary syndrome also has value in diagnosis and management. The concentration of CRP ( 3mg/dl to >200mg/dl ) at
which it is detectable in serum is not sensitive for the value required to determine the cardiovascular risk in otherwise healthy person...........

Keywords: FNAC, USG, HPE, Thyroid Nodule.

[1]. FOUSSAS SG, Zairis MN, Katsaros et al. Early prognostic usefulness of C reactive protein added to thrombolysis in myocardial
infarction risk score in acute coronary syndrome .Aug 2005;96;P533-537
[2]. Suleiman, AronsonD, LEVY et alAdmission C reactive protein levels and 30 day mortality in patients with acute myocardial
infarction ,Dec 2003,115;9 p695-701
[3]. Distefavo R ,CarpiA. Inflammatory markers and cardiac function in acute coronary syndrome. Differernce in STEMI and in
NSTEMImodels 2009 Dec: 773-80
[4]. Habib SS, Kurdi MI. hsCRP levels are higher in patients with ST elevation than non ST elevevation acute coronary syndrome 2011
Jan;96(1)
[5]. Hersberg PI, Hematocrit and prognosis in patient with acute myocardial infarction, JAMA 1973;219;;855

Abstract: PRP injections have been proposed as a promising alternative for treating tendinopathies. Platelets release various cytokines and growth factors which promote angiogenesis, tissue remodeling, and wound healing. In this studyPRP prepared by drawing blood from patient, centrifuging it , prp(3 to 10 times of the whole blood) will be injected over pathological tendon site over maximum point of tenderness, followed by immobilization of the part for 3 days ,followed by eccentric loading exercise for 6 weeks and results assessed
clinically,visual analogue scale at regular interval .............

[1]. Kannus P, Natri A. Etiology and pathophysiology of tendon ruptures in sports. Scand J Med Sci Sports 1997;7:107‑12.
[2]. Available from: http://orthoinfo.aaos.org/topic. cfm?topic=A00525 [Last accessed on 25th Nov. 2013].
[3]. Roberts TT, Rosenbaum AJ. Bone grafts, bone substitutes and orthobiologics: The bridge between basic science and clinical
advancements in fracture healing. Organogenesis 2012;8:114‑24.
[4]. Paoloni J, De Vos RJ, Hamilton B, Murrell GA, Orchard J. Platelet‑rich plasma treatment for ligament and tendon injuries. Clin J
Sport Med 2011;21:37‑45
[5]. Wehling P, Moser C, Frisbie D, McIlwraith CW, Kawcak CE, Krauspe R, et al. Autologous conditioned serum in the treatment of
orthopedic diseases: The orthokine therapy. Bio Drugs 2007;21:323‑32.

Abstract: Osteomas are the slow growing benign tumours of the lamellar bones. They are the most common benign neoplasm of nose and paranasal sinuses. But osteomas of the temporal bone are rare and that of the zygomatic process are very very rare. In this case, we present a 38 years old female patient with osteoma of the zygmatic process of the left temporal bone. The osteoma was excised under General anaesthesia and the excised specimen was send for histopathology examination. The report came out to be osteoid osteoma. In this article, we present the incidence and clinicopathological features of osteoma.

Keywords: osteoma, osteoid osteoma, exostoses.

[1]. Larem, A. , Sheta, S. , Al-Qahtani, A. and Haidar, H. (2015) Stylomastoid Foramen
[2]. Osteoma: Unique Challenges for Appropriate Management. International Journal ofOtolaryngology and Head & Neck Surgery,4,
277-281. doi:10.4236/ijohns.2015.44047.
[3]. Parelkar, K. , Thorawade, V. , Jagade, M. , Kar, R. , Pandare, M. , Nataraj, R. , Hanwate, R. , Attakil, A. and Kashide, R. (2014)
Osteoma of Temporal Bone—A Rare Case report.
[4]. International Journal of Otolaryngology and Head & Neck Surgery, 3, 252-258.doi: 10.4236/ijohns.2014.3504.
[5]. Bryan, E. and Kalina, P. (2013) Early Initial Diagnosis of Gardner Syndrome in a 12-YearOld Boy. Advances in Computed
Tomography, 2, 1-3. doi: 10.4236/act.2013.21001

Abstract: Background: Magnesium has been used in the treatment of acute exacerbation of asthma for a long time, but the role of hypomagnesaemia in chronic stable asthma and its prognostic implications have not been fully established. Objectives:We conducted this study – (i)To assess the levels of serum magnesium and its prognostic implications in patients with chronic stable asthma and (ii) to find out any correlation between the severity of asthma and hypomagnesemia. Setting: Government Rajaji hospital ,Madurai, TamilNadu............

Keywords: Chronic stable asthma, Magnesium, Disease severity, Spirometry.

[1]. National Asthma Education and prevention programme. Expert panel report3 2007

[2]. Data from Global from initiative for Chronic Obstructive Lung Disease (GOLD) Global strategy for the diagnosis , mamagement and prevention of COPD ,Updated 2011.

[3]. Picado C Classification of severe asthma exacerbations: a proposal. Eur Respir J. 1996 Sep;9(9):1775-8

[4]. NIH and WHO guidelines .Asthma management and prevention. Global initiative for asthma – Global strategy for asthma management and prevention. GINA guidelines updated 2009.

[5]. Guidelines for evaluation of impairment or disability in patients with Asthma ; American Thoracic Society : Vol 147 . pp 1056 -61 , 1993.

Abstract: Aim: To evaluate the advantage of using a single incision by Stoppa's procedure for Bilateral inguinal hernia in comparison with two incisions on either side by Lichtenstein's hernioplasty. Methods: Forty six cases of Bilateral inguinal hernia admitted in the department of General surgery in madurai&thoothukudi medical college and hospitals. Two groups were made. One group underwent single incision Stoppa's procedure and the second group underwent Bilateral Lichtenstein's hernioplasty and the results were tabulated and evaluated.............

Keywords: lichtenstein , hernioplasty , stoppas , mesh , postoperative.

[1]. Talha AR, Shaaban A, Ramadan R. Preperitoneal versus Lichtenstein tension-free hernioplasty for the treatment of bilateral inguinal hernia. Egypt J Surg 2015;34:79-84

[2]. Stoppas procedure: place in present era. IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) e-ISSN: 2279-0853, p-ISSN: 2279-0861. Volume 13, Issue 5 Ver. I. (May. 2014), PP 75-76.

[3]. Comparative study of laparoscopic TEP over Stoppa's and Lichtenstein technique for the management of bilateral inguinal hernia- A prospective study international. Journal of Development Research Vol. 4, Issue, 5, Pp. 1031-1034, May, 2014

[4]. Giant prosthetic reinforcement of the visceral sac: the Stoppa groin hernia repair in 234 patients, From the Department of Surgery, Tabriz University of Medical Sciences, Faculty of MedicineTabriz, Iran,Accepted for publication: February 2005,Ann Saudi Med. 2005;25(3):228–232

[5]. Preperitoneal hernioplasty via Pfannenstiel approach for recurrent inguinal hernia. Sci. Med. J. Cai. Med. Synd., Vol. 2,No. 3, July 1990

Abstract: Local flaps have been commonly used in the reconstruction of facial defects left after excision of primary tumours. The forehead flap (median and laterally based) can be used to close defects in the cheek and floor of the mouth, its pedicle can be used to close defects in the maxilla. In a seventh century Indian medical document, the Sushruta Samita, describes a technique of using a flap from the forehead for nasal restoration. The forehead flap is relatively simple in concept and technique. It is widely used for nasal reconstruction. The importance of this flap is due to its versatility . This flap has been described as the most robust and dependable flap. In addition, it has the advantage of having large arc of rotation...........

[1]. Rohrich RJ, Griffin JR, Ansari M, Beran SJ, Potter JK. Nasal reconstruction-beyond aesthetic subunits: A 15-year review of 1334 cases. Plast Reconstr Surg. 2004;114:1405–19

[2]. Herford AS, Ghali GE. 3rd ed. USA: People's Medical Publishing House; 2010. Local and Regional Flaps. Peterson's Principles of Oral and Maxillofacial Surgery; p. 773.

[3]. Menik FJ. Paramedian Forehead Flap E. Medicine.

[4]. Utilization of the pedicle of the temporal-forehead-flap to close defects in the maxilla after tumour surgery : M. Frans Noorman van der Dussen *,journal of maxillofacial surgery ,volume 11, 1983.

Abstract: T-prolymphocytic leukaemia (T-PLL) is a rare mature T-cell lymphoproliferative disorder. It is seen more often in middle-aged and elderly individuals with a median age of onset of 65 years and a male predominance of 2:1. Patients present with hepatosplenomegaly, lymphadenopathy, 15% may have serous effusions and approximately 20% have skin involvement. The white cell count is often above 200 x 109/l, and the tumour cells are CD3+, CD4+ or CD8+ (co-expression of CD4 and CD8 in 25%), CD7+, and are CD25-. The disease has an aggressive clinical course due its inherently chemoresistant nature, with a median survival of 7 months on conventional chemotherapy............

Keywords: T-cell prolymphocytic leukaemia, aggressive course, poor prognosis, South Africa

[1]. Swerdlow S, Campo E, Harris N, editors. World Health Organization Classification of Tumours of Haematopoietic and Lymphoid Tissues. Lyon: IARC Press; 2008.
[2]. Dearden C. How I treat prolymphocytic leukemia. Blood. 2012 Jul 19;120(3):538-51. PubMed PMID: 22649104. Epub 2012/06/01. eng.
[3]. Graham RL, Cooper B, Krause JR. T-cell prolymphocytic leukemia. Proc (Bayl Univ Med Cent). 2013 Jan;26(1):19-21. PubMed PMID: 23382603. Pubmed Central PMCID: 3523759. Epub 2013/02/06. eng.
[4]. Foucar K. Mature T-cell leukemias including T-prolymphocytic leukemia, adult T-cell leukemia/lymphoma, and Sezary syndrome. Am J Clin Pathol. 2007 Apr;127(4):496-510. PubMed PMID: 17369126. Epub 2007/03/21. eng.
[5]. Dearden C. Alemtuzumab in peripheral T-cell malignancies. Cancer Biother Radiopharm. 2004 Aug;19(4):391-8. PubMed PMID: 15453953. Epub 2004/09/30. eng

Abstract: RCT's has been recognised as the standard method for rationalising treatment outcomes in medical literature. However, many researchers are still unfamiliar with how to properly randomize the study, and it has been shown that there are limitations in studies due to inaccurate performance of the randomization, leading to errors in results, even though they published in indexed International journals. This review on randomization trials, help researchers to develop the skills for critically analysing RCT's in terms of methodology, magnitude and precision of treatment.

[1]. Evans D (2003) Hierarchy of evidence: a framework for ranking evidence evaluating healthcare interventions. J Clin Nurs 12: 77-84
[2]. Ranjita G (2005) "Interferon-alpha-induced depression: when a randomised trial is not a randomised controlled trial". Psychother Psychosomatic 74(6): 387. doi: 10.1159/000087787 PMD 16244516
[3]. Streptomycin in Tuberculosis Trials Committee (1948)"Streptomycin treatment of pulmonary tuberculosis. A Medical Research Council investigation" Br Med J 2(4582): 769-82
[4]. Moher D, Hopewell S, Schulz KF, Montori V, Gotzsche PC, Devereaux PJ, Elbourne D, Egger M, Altman DG (2010) "CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials". Br Med J 340: c869

[5]. Sackett DL, Strauss SE, Richardson WS, et al. (2000) Evidence based medicine. How to practice and teach EBW London: Churchill-Livingstone

Abstract: Introduction: Liver cirrhosis is a major health problem world-wide and peptic ulcer is a condition that is commonly seen in patients with liver cirrhosis.Helicobacter pylori infection remains one of the most common conditions in Liver cirrhosis patients. Thisstudy was done to ascertain the presence of H. pylori in patients with liver cirrhosis being treated a tertiary care hospital in rural part of South India, in both symptomatic and asymptomatic peptic ulcer disease patients. Methodology: All consecutive patients with liver cirrhosis with or without obvious symptoms of peptic ulcer disease (PUD), attending the gastroenterology department of a rural tertiary care center in Southern India was serially recruited after taking written informed consent to join the study...........

[1]. Kusters JG, van Vliet AH, Kuipers EJ: Pathogenesis of Helicobacter pylori infection. ClinMicrobiol Rev 2006; 19:449-90.
[2]. Ernst PB, Peura DA, Crowe SE: The translation of Helicobacter pylori basic research to patient care. Gastroenterology 2006; 130:188-206
[3]. Suerbaum S, Michetti P: Helicobacter pylori infection. N Engl J Med 2002; 347:1175-86.
[4]. Amieva MR, El-Omar EM: Host-bacterial interactions in Helicobacter pylori infection. Gastroenterology 2008; 134:306-23.
[5]. M. Rudler, G. Rousseau:Peptic Ulcer Bleedin

Abstract: Context: Compound fractures of tibia pose a significant challenge to orthopaedic surgeons due to its precarious blood supply, subcutaneous location and poor soft tissue coverage, leading to various complications. This study evaluates the operative outcomes of interlocking intramedullary nailing with reaming for open tibial shaft fractures. Aims: To study the clinical, radiological and functional outcomes, and complications associated with the procedure. Materials and methods: Interlocking Intramedullary Nailing of 30 cases of open tibialdiaphyseal fractures and evaluation of the results. Statistical Analysis Used:Patients evaluated clinically and radiologically, at regular intervals...........

Keywords: interlocking nail, tibia, reaming, open fractures

[1]. Kuntscher G: Practice of intramedullary nailing.J Bone Joint Surg 40A:17,1958
[2]. Ando K ,Yamaji T. Interlocking nailing for tibia shaft fractures. J. Orthop Sci.2000;5:217-222.
[3]. Court-Brown CM, McBirnie J. The epidemiology of tibial fractures. J Bone Joint Surg [Br] 1995;77-B:417-21.
[4]. Coles CP, Gross M. Closed tibial shaft fractures: management and treatment complications: a review of the prospective literature. Can J Surg 2000;43:256-262
[5]. Sakaki MH, Crocci AT, Zumiotti AV (2007) Comparative study of the locked intramedullary nail and Ender pins in the treatment of tibial diaphyseal fractures. Clinics; 62:455-464.

Abstract: Isolated gall bladder injury after blunt trauma abdomen is a rare entity. Its anatomical location allows it to be protected by the liver, intestines, the omentum, and ribs therefore isolated injury of gall bladder is a rare. Due to this the diagnosis is often made during an exploring laparotomy. There is high morbidity and mortality due to delayed diagnosis. Here we are reporting two cases of traumatic isolated gall bladder perforation in the emergency at the stage of peritonitis, then was diagnosed after laparotomy and managed by open total cholecystectomy...........

Keywords: Gallbladder perforation; Biliary peritonitis; Exploratory laprotomy; CECT of abdomen; Total cholecystectomy.

[1]. Penn, I. Injuries to the gallbladder. Br. J. Surg. 1966;49, 636-641.
[2]. Wiener, I., Wastson, L.C. and Wolma, F.J. Perforation of gallbladder due to blunt abdominal trauma. Arch. Surg. Ann. Surg. 1982;117,805-807.
[3]. Soderstrom, C.A., Maekawa, K, Du Priest,R.W.Jr and Cowley, R.A. Gallbladder injuries resulting fromblunt abdominal trauma. Ann. Surg. 1981;193, 60-66.
[4]. Kim SH, Lee KJ, Kim HR, Kim SJ, Lee SC, Kim JG, LeeDH, Ann CJ. Isolated traumatic Gallbladder Rupture. J. Korean Surg SOC. 2008;75(2):145-148.
[5]. Brainbridge J, Shaaban H, Kenefick N, Armstrong CP. Delayed presentation of an isolated Gallbladder rupture following blunt abdominal trauma: a case report. J Med Case Reports 2007; 1(52): 294-295.

Abstract: Intracerebral cavernomas represent 5-10% of all vascular malformations of the central nervous system. Their location in the third ventricle is very rare. Only about a hundred cases have been reported in the literature so far. We present for the first time a case of third ventricular cavernoma encountered in a 39-year-old patient admitted in our department, while detailing the various difficulties encountered in the management of this rare entity

Keywords: cavernoma – third ventricle – transcallosal approach.

[1]. Mohana Rao Patibandla, Amit Kumar Thotakura & Manas Kumar Panigrahi, Third ventricular cavernous malformation, an unusual lesion, British Journal of Neurosurgery, Aug 2013
[2]. Faropoulos K, Panagiotopoulos V, Partheni M, Tzortzidis F, Konstantinou D J, Therapeutic management of intraventricular cavernoma: case series and review of the literature, Neurol Surg, 2015 May
[3]. Z. Milenkovic Z. Milenkovic, Neurosurgical Clinic, Medical Faculty of Nis, Postural intermittent headaches as the initial symptom of a cavernoma in the third ventricle, Acta Neurochirurgica, 30 September 2004
[4]. A. Alves de Sousa Hôpital Santa Casa, hôpital Lifecenter, Belo Horizonte, Brésil, Cavernomes profonds (corps calleux, intraventriculaires, ganglions de la base, insulaires) et du tronc cérébral, expérience d'une série brésilienne, j.neuchi 2007.03.008
[5]. Hiroaki Nagashima Kazuhiro Tanaka, Takashi Sasayama, Yusuke Okamura, Masaaki Taniguchi, Kyoko Otani, Takashi Yamasaki, Tomoo Itoh, Eiji Kohmura, A large cavernous malformation of the third ventricle floor: A case report Department of Neurosurgery, Kobe University Graduate School of Medicine, Kusunoki cho, Chuoku, Kobe, Japan, 2015.08.004

Abstract: Forestier's disease is a musculo-skeletal disorder characterized by diffuse exuberant hyperostosis in anterolateral faces of the vertebral bodies essentially affecting the anterior longitudinal ligament. It generally affects males over 50 years. It is often incidentally discovered on standard spine X rays. Even more rarely, it manifests by neck stiffness, pain or dysphagia. We present a case of a 70 years old patient with difficulty in swallowing solids for several months. Pharyngo-laryngoscopy revealed a bulging of the pharyngeal wall indicating an extrinsic compression. Barium swallow showed paravertebral ossification affecting five consecutive vertebrae from C3 to C7. CT-scan confirmed the osseous proliferation with a split between the vertebral body and the hyperostosis confirming the diagnosis of Forestier's disease...........

Keywords: Forestier's disease – ligamental ossification – dysphagia

[1]. Forestier J, Rote-querol J. Senil ankylosis hypperostosis of the spine, Ann Rheum. 1950; 9: 321-330.
[2]. Kiss C, Szilagyi M, Pasky A, Poor G. Riskfactors for diffuse idiopathic skeletal hyperostosis: a case-control study J Afr Imag, med 2014; (6), 4: 66-69 Rheumatology 2002; 41 : 27-30
[3]. HarigaI., MbarekCh, OuniH,ChammekhiCh, Ben Gamra O, Ben Amor M, Zribi S, El khedim A. Maladie de forestier révélée par une dysphagie. A propos de deux cas. J.TUN ORL 2007 ;18 : 55-57.
[4]. Aydin E, Akdogan V, Akkuzu B. Six cases of forestier syndrome, a rare cause of dysphagia. Acta Otolaryngol. 2006; 126: 775-778. PUBMED
[5]. Squadrito G, Reale F, D'Agostino G, Combined diagnostic imaging in a patient with Forestier disease and dysphagia. Rays 2005; 30(3) :251-5

Abstract: Central haemangioma of the mandible and maxilla is extremely rare. Intraosseous haemangioma comprises less than one percent of all intraosseous tumours. Intraosseous vascular lesions of maxillofacial region are challenging to diagnose considering other jaw lesions. This article describes a case of central haemangioma of mandible with clinical, radiological and histological features which was treated with segmental resection of mandible............

Keywords : Central haemangioma, body of mandible, segmental resection,embolization, radiation

[1]. Alves S, Junqueira JL, De Oliveira EM, Pieri SS, De Magalhães MH, Dos Santos Pinto D Jr, et al. Condylar hemangioma: report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral RadiolEndod.102(5) 2006, e23-7.
[2]. Williams HJ, Wake MJ, John PR. Intraosseous haemangioma of the mandible: a case report. PediatrRadiol.32(8), 2002,605-8.
[3]. Cheng NC, Lai DM, Hsie MH, Liao SL, Chen YB. Intraosseous hemangiomas of the facial bone.PlastReconstr Surg.,117(7), 2006, 2366-72.
[4]. Drage NA, Whaites EJ, Hussain K. Haemangioma of the body of the mandible: a case report. Br J Oral Maxillofac Surg.,41(2),2003,112-4.
[5]. Shira RB, Guernsey LH. Central cavernous hemangioma of the mandible: Report of a case. J Oral Surg, 23, 1965, 636-42.

Abstract: Objective: To compare the beneficial and harmful effects of tobacco use and cigarette smoking on oral health. The methodology used: A structured review of the articles which are analyzed and which were concerned about the effect of smoking either positive or negative on oral health. We have included the articles primarily of last decade. Discussion: Few articles show the positive effect of smoking and tobacco use, while the most of the articles show the negative impact of smoking and tobacco use especially on oral status...........

Key words: Tobacco, Cigarette, positive effect, harmful effect, habit

[1]. Derek Yach, Douglas Bettcher Globalisation of tobacco industry influence and new global responses Tobacco Control 2000;9:206–216
[2]. Millar WJ, Locker D. Smoking and oral health status. J Can Den Assoc 2007;73:155.
[3]. Meraw SJ, Mustapha IZ, Rogers RS. Cigarette smoking and oral lesions other than cancer. Clin Dermatol 1998;16:625-31.
[4]. Zambon JJ, Grossi SG, Matchtei EE, Ho AW, Dunford R, Genco RJ. Cigarette smoking increases the risk for subgingival infection with periodontal pathogens. J Periodontol. 1996 Oct;67(10 Suppl):1050-4.
[5]. Kinane DF, Bartold PM: Clinical relevance of the host responses of periodontitis. Periodontol 2000 2007;43:278-293

Abstract: Background: Well motivated health professionals can be good role models for the communities. Detection of predisposing factors of diseases like hypertension, Diabetes, obesity, anemia etc. is vital in modification of life style diseases particularly in teenagers. Prevalence studies of risk factors of non-communicable diseases and other predisposing factors of ill health in medical students are very few. So the main aim of this study is to know the prevailing risk factorsandto educate the students about Preventive measures. Methodology: A cross sectional study was conducted on 149 first year medical students at Gayatri Vidya Parishad Institute of Health Care and Medical Technology, Visakhapatnam, India..........

Key words: Non-communicable diseases, Risk factors, under graduate medical students

[1]. King H,Aubert RE,Homan WH.Global burden of Diabetes,1995- 2005.Prevalance,numerical estimates and projections.Diabetic Care.1998,21:1414 - 31
[2]. Reddy KS, Yusuf S. emerging epidemic of CVDs in developing countries – Circulation .1998:97:596-601.
[3]. K.Park. Park‟s Textbook of Preventive and social Medicine. 24thEdn. Jabalpur :M/S BanarasidasBhanot: Jan-2017. p-381
[4]. Suryakantha AH. Community Medicine with Recent Advances 3rd Edition. New Delhi: Jaypee Brothers Medical publishers(p)Ltd; C 2014. p -523.
[5]. Awareness of NCDs and their Risk Factors among rural school children. Indian journal of community Health. Oct2012 – Dec 2012 Vol 24,No.4.

Abstract: Stress has been described as a disease of the 21st century. The current pilot research was an attempt to study the effect of Mindful Life Management, a Mindfulness Based Intervention on perceived stress among a group of healthy volunteers The 10 study participants were volunteers who enrolled for the 8 week MLM program. The main tools used for the study were a specially prepared semi-structured proforma for collecting the socio-demographic data, Mini Mental Status Examination (MMSE), Perceived Stress Scale (PSS), and Five Facet Mindfulness Questionnaire (FFMQ). Each facets in FFMQ significantly varied in their mean score before and after MLM training and self- practice. Highest changes were observed in Non- Judgment and Awareness. A significant correlation was established in each facet and Five Face Mindfulness Questionnaire Score as a whole with Perceived Stress...........

[1]. Kabat-Zinn, J. (1990). Full catastrophe living: Using the wisdom of your body and mind to face stress, pain and illness. New York: Delacourt.

[2]. Kabat-Zinn, J. (2003). "Mindfulness-based interventions in context: past, present, and future." Clinical Psychology: Science & Practice 10(2): 144-156.

[3]. Hayes, S. C., Luoma, J., Bond, F., Masuda, A., & Lillis, J. (2006). Acceptance and Commitment Therapy: Model, processes, and outcomes. Behaviour Research and Therapy, 44(1), 1-25.

[4]. Grossman P, Niemann L, Schmidt S, Walach H. (2004). Mindfulness-based stress reduction and health benefits. A meta-analysis. J Psychosom Res 57: 35-43.

[5]. Fjorback, L. O., Arendt, M., Ornbol, E., Fink, P., &Walach, H. (2011). Mindfulness-based stress reduction and mindfulness based cognitive therapy – A systematic review of randomized controlled trials. ActaPsychiatricaScandinavica, 124(2), 102-119

Abstract: Background: complicated malaria is the most dangerous and notorious complication of severe falciparum malaria. In the present study 100 cases with clinical features of complicated malaria (WHO criteria) were included and randomly allocated into two equal groups. One group received i.v. quinine and the other group received i.v. artesunate. Objective: To find out the outcome in terms of relative efficacy and overall cure rate for both drugs, employed for therapy. Methodology: The study was carried out in the Department of Pediatrics, Rajendra Institute of Medical Sciences, Ranchi in which Patients presenting with features of severe malaria and positive blood film for P. falciparum were taken for study,excluding those with no asexual form of P. falciparum or with multispecies forms of malarial parasite in peripheral smear, G6PD deficient cases and cases with hepatitis or renal failure due to other causes............

Key words: Artesunate, quinine, cerebral malaria, outcome and efficacy.

[1]. WHO(2008), World Malaria Report 2008.
[2]. WHO Expert Committee on Malaria. Twentieth report. Geneva, World Health Organization, 2000 (WHO Technical Report Series, No: 892).
[3]. Govt Of India (2007), NRHM News letter, vol. 3, No.2, July-Aug.
[4]. 2007, National Rural Health Mission, Dept of Health and Family Welfare, New Delhi.
[5]. Preventive & Social Medicine – Park - ed.
[6]. Essential Pediatrics – TB – O.P. Ghai – 7th ed. Pg: 227-236.

Abstract: Aim: Snake envenomation is a major cause of death and disability in the developing countries, particularly in South East Asia. Since 1894, commercial snake venom antiserum developed by Calmette is the only specific treatment available for snake bite. The use of plants against the effects of snakes bite has been long recognized; more scientific attention has been given since last 20 years (Santosh et al., 2004). The folklore uses of Indian Medicinal Plant Alstonia scholaris Linn against snakebite treatment has been validated in the present study. Methods & Materials: Viper venom neutralizing activity neutralization with 200mg/kg bw aqueous extract of Alstonia scholaris Linn(AAS) was estimated by in vivo methods in animal models............

Key words: Aqueous Alstonia scholaris(AAS), Minimum edema dose(MED), minimum defrinogenating dose(MDD), minimum necrotizing dose(MND).

[1]. Bhardwaj A., Sokhey J. Snakebites in the hills of North India. Nat. Med. J. Ind., 1998, 11, 264-265.
[2]. Bawaskar H S. Snake venoms and antivenoms: critical supply issues. Journal of the Association of Physicians of India. 2004; 52: 11–13.
[3]. Maya Devi, C., Vasantha Bai, Mary, Vijayan Lal, Arthur, Umashankar, P.R., Krishnan, Lissy K. 2002. An improved method for isolation of antiviper venom antibodies from chicken egg yolk. Journal of Biochemical and Biophysical Methods. 51: 129–138.
[4]. Meenatchisundaram S, Prajish, Parameswari G, Subbraj T, Michael A. Studies on antivenom activity of Andrographis paniculata and Aristolochia indica plant extracts against Echis carinatus venom. The Internet Journal of Toxicology 2008;6(1):1559-3916.
[5]. Alam MI and Gomes A (2003) Snake venom neutralization by Indian medicinal plants (Vitex negundo and Emblica officinalis) root extracts. J. Ethnopharmacol. 86, 75–80.