iosr-JDMS   Volume-19 ~ Issue-7 ~ JuLy 2020

Abstract: Introduction:Metastatic spine tumors are a frequent problem in patients afflicted with cancer and are oftenassociated with significant morbidity and mortality. The The most common symptom is pain, present in up to 85–96 % of cases . Pain can be caused from periosteal stretching and inflammation from local tumor growth, which results in constant, dull, nocturnal pain. Spinal metastases can also result in spine instability, which can lead to mechanical pain that worsens with movement or axial loading. Case report:We report the successful management of a 57 year old neurologically sound patient with dorsal spine metastasis associated with morphine dependency due to severe pain; treated with combo minimal invasive procedures- percutaneous vertebroplasty and posterior percutaneous.....

Keywords: spine tumors, metastasis

[1]. K. D. Harrington, "Metastatic disease of the spine," Journal of Bone and Joint Surgery, vol. 68, no. 7, pp. 1110– 1115, 1986.
[2]. * D. M. Sciubba, R. J. Petteys, M. B.Dekutoski et al., "Diagnosis and management of metastatic spine disease: a review," Journal of Neurosurgery: Spine, vol. 13, no. 1, pp. 94–108, 2010.
[3]. * D. M. Sciubba and Z. L. Gokaslan, "Diagnosis and management of metastatic spine disease," Surgical Oncology, vol. 15, no. 3, pp. 141–151, 2006.
[4]. - "‟Current concepts in the management of metastatic spinal disease "‟ K.Singh, D.Samartzis, A.R.Vaccaro , G.B.S.Anderson, H.S.An , J.G.Heller
[5]. - Joseph H. Schwab,1 Alessandro Gasbarrini, Michele Cappuccio,LucaBoriani, Federico De Iure, Simone Colangeli,and Stefano Boriani JUNE 2011

Abstract: BACKGROUND : Anaemia during pregnancy is most common cause of adverse maternal and perinatal outcomes. Anaemia during pregnancy treated by various routes. This study will evaluate the effects of ferric carboxymaltose in antenatal patients and its Feto-Matenal Outcomes. MATERIALS & METHODS : This is a prospective study. Study was carried out at tertiary care centre, on 100 Antenatal patients having iron deficiency anaemia. After investigations and dose calculation, inj. FCM (Ferric carboxymaltose) was administered with proper aseptic precautions and monitoring. Patients were evaluated at the end of 3 weeks......

Key Word: FCM (Ferric carboxymaltose), Hemoglobin (Hb), Multigravida, Anaemia, Anaphylactic reaction

[1]. De Mayor EM, Tegman A, Prevalence of Anaemia in the world, world Health Organisation 1998;38:302-16.
[2]. WHO, WHO global database on anaemia / Edited by Bruno de Benoist,Erin McLean, Ines Egli and Mary Cogswell, 2008. http://whqlibdoc.who.int/publications/2008/9789241596657_eng.pdf retrieved on July February 6th, 2014.
[3]. JL Beard, J Nutr, 2005, 135, 267 – 274.
[4]. Kalaivani K. Prevalence and consequences of anaemia in pregnancy. Indian J.Med Res. 2009:627-33.
[5]. Roy S. Chakravorty PS Maternal and peri -natal outcome in severe anemia, J Obs Gynae Ind 1992;42:74350.

Abstract: Background:Abnormal uterine bleeding (AUB) is a common gynecological problem in women, affecting their quality of life and making them seek treatment. AUB has many causes which makes it important to have a systematic approach that can lead to the correct diagnosis and guide management accordingly. The primary aim is to study the various causes of AUB and categorize the women presenting with the complaint as per the FIGO PALM-COEIN system after reaching a final diagnosis based of clinical, laboratory, imaging and histopathology findings. The study also enables to compare the different causes of AUB as per the frequency of occurrence. Materials & Methods: An observational study was carried out on a 100 women in the reproductive age group, who presented with the complaint.....

Key words: Abnormal uterine bleeding, PALM-COEIN, leiomyoma

[1]. Fraser IS, Critchley HO, Munro MG, et al. Can we achieve international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding? Hum Reprod 2007; 22(3):635-643 [2]. NICE. Clinical Guideline 44; Heavy menstrual bleeding 2007. National Institute for Health and Clinical Excellence (NICE)
[3]. Fraser IS, Critchley HO, Munro MG. The two FIGO systems for normal and abnormal uterine bleeding symptoms and classification of causes of abnormal uterine bleeding in the reproductive years: 2018 revisions
[4]. Ryan GL, Syrop CH, Van Voorhis BJ. Role, epidemiology, and natural history of benign uterine mass lesions. Clin Obset Gynecol 2005;48(2):312-314
[5]. FIGO Committee for Menstrual Disorders, Duration: 2015 – 2021, Chair: Professor Malcolm Munro, USA.

Abstract: Anemia is a common and predominant blood disorder globally, in which the level of hemoglobin or healthy red blood cells are abnormally lower. The most common type anemia is Iron deficiency anemia (IDA). In Siddha system Veluppu Noi is almost correlated with clinical conditions of anemia as described in modern medicine. Veluppu is described as a diseased condition in which the nature color of the body including nail beds and conjunctiva becomes pallor. Siddha system has better medicines for the treatment and management of Veluppu Noi. One among them is Vallarai Nei the ingredients of this preparation contains as its chemical constituents iron, folic acid, vitamin C, vitamin B12, copper, zinc, carbohydrate, protein, tannin, flavonoids. The ingredients of this medicine exhibits anti-oxidant, anti-microbial, immunomodulatory and hepatoproductive. The medicine improved both the haemoglobin level in RBC's and also strength in the immune system.

Key words: Iron deficiency anemia, Veluppu Noi, Vallarai Nei

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[5] Sakshi Singh, Asmita Gautam, Abhimanyu Sharma and Amla Batra. Centella asiatica (l.): a plant with immense medicinal potential but threatened. Jaipur, India. International Journal of Pharmaceutical Sciences Review and Research. September – October 2010.Volume 4, Issue 2, Article 003. P 9-17..

Abstract: Hypertriglyceridemia (HTG) is a rare but well known cause of acute pancreatitis (AP), after alcohol and gall stone disease. It is alleged to account for up to 10% of all pancreatitis episodes. Studies suggest that in patients with triglyceride (TG) levels>1000 mg/dL (>11.3 mmol/L), hypertriglyceridemia-induced acute pancreatitis (HTGP-AP) occurs in approximately 15-20% of all subjects referred to Lipid Clinics. This can be a life- threatening complication if the degree of HTG is severe enough. It might be primary in origin or secondary to alcohol abuse, diabetes mellitus, pregnancy, or drugs. A serum triglyceride (TG) level of more than 1,000 to 2,000 mg/dL in patients with type I, IV, or V hyperlipidemia (Fredrickson's classification) is the identifiable risk factor. A thorough family history of lipid abnormalities should be obtained, and an attempt to identify secondary causes should be made. HTG-induced AP typically.....

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[3]. L. Linares, A. L. Pelletier, S. Czernichow et al., ―Acute pancreatitis in a cohort of 129 patients referred for severe hypertriglyceridemia,‖ Pancreas, vol. 37, no. 1, pp. 13–22, 2008.
[4]. S. Sandhu, A. Al-Sarraf, C. Taraboanta, J. Frohlich, and G. A. Francis, ―Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study,‖ Lipids in Health and Disease, vol. 10, article 157, 2011. K. Bessembinders, J. Wielders, and A. van de Wiel, ―Severe hypertriglyceridemia influenced by alcohol (SHIBA),‖ Alcohol and Alcoholism, vol. 46, no. 2, Article ID agq088, pp. 113–116, 2011..
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Abstract: Infectious diseases are major public health problem globally in terms of mortality andmorbidity. Human genetic variation exerts a major influence on the course of disease caused by many infectious micro-organisms. However, host immunity and susceptibility is affected by many environmental factors such as nutritional status,intercurrent disease, pregnancy, immunosuppressive drugs and malignancy. Advanced DNA technology has mapped human genome and identified genes that are involved and related to resistance and susceptibility to most common microbial infections. Genome-wide association studies have identified various strong association between genetic polymorphisms and susceptibility to infectious disease phenotypes. Thisresulting the development of new branch in medicine and therapy, the personalized medicine. Understanding the human genome individual variations and specific polymorphism enabling potential selective therapy with best response and highest safety margin to ensure better patient care and treatment .Paper discuss the susceptibility and resistance to some of common pathogenic microbial infection related to the genome variation.

Keys words: Genetic, Humaninfection, Disease and genetic link, Genetic disease axis

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Abstract: COVID-19 is currently a public health emergency of international concern that needs to be addressed as soon as possible through effective medical intervention.1 This is a contagious respiratory illness which spreads from person to person via close contact, infected droplets or interaction with surfaces that contain the virus. The first case of COVID-19 was identified in Wuhan, China and reported to World Health Organisation on 31 December 2019.2 On 30 January 2020, World Health Organisation declared COVID-19 a pandemic.3 SARS-CoV-2 is highly contagious and potentially fatal for some people who contract it. This study has been planned to assess knowledge pertaining to patients infected with SARS-CoV-2 amongst the health care professionals working in the COVID- 19 treating center. Knowing the level of knowledge in the early stages of pandemic can help in organizing relevant training and framing policies during the outbreak.

[1]. COVID-19 as a Public Health Emergency of International Concern (PHEIC) under the IHR | Strategic Partnership for IHR and Health Security (SPH) [Internet]. [cited 2020 Jul 21]. Available from: https://extranet.who.int/sph/covid-19-public-health-emergency-international-concern-pheic-under-ihr
[2]. Wu Y-C, Chen C-S, Chan Y-J. The outbreak of COVID-19: An overview. Journal of the Chinese Medical Association. 2020 Mar;83(3):217–220.
[3]. Jee Y. WHO International Health Regulations Emergency Committee for the COVID-19 outbreak. Epidemiol Health [Internet]. 2020 Mar 19 [cited 2020 Jul 21];42. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7285442/
[4]. Lauer SA, Grantz KH, Bi Q, Jones FK, Zheng Q, Meredith HR, et al. The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application. Annals of Internal Medicine. 2020 Mar 10;172(9):577–82.
[5]. Metlay JP, Waterer GW. Treatment of Community-Acquired Pneumonia During the Coronavirus Disease 2019 (COVID-19) Pandemic. Annals of Internal Medicine [Internet]. 2020 May 7 [cited 2020 Jul 21]; Available from: https://www.acpjournals.org/doi/10.7326/M20-2189

Abstract: Wound dehiscenes is the most dreaded complications faced by surgeons having incidence ranges from 0.4% to 3.5% in post operative patients. It is of greatest concern because of risk of evisceration, the need for immediate intervention, and the other complications and has mortality rates reported as high as 45%. Various risk factors are responsible for wound dehiscence such as emergency surgery, intraabdominal infection, malnutrition (hypoalbuminaemia ,anaemia), advanced age >65yrs, systemic diseases( uremia, diabetes mellitus) etc. This retrospective observational study which was carried out on 50 patients clinically presenting as gaping of abdominal wound and discharge from the surgical site admitted in Department of Surgery, People's College of Medical.....

[1]. .Waqer S, Malik Z, Razzaq A, et al.: Frequency and risk factors for wound dehiscence/burst abdomen in midline laparotomies. Journal Ayub Med Coll 2005, 17(4):70-73.
[2]. Spiliotis J, Konstantino S, Tsiveriotis, Datsis AD, Archodaula, Georgios et al. Wound Dehiscence. World Journal of Emergency surgery 2009;4:12.
[3]. Gabrie¨lle H. van Ramshorst • Jeroen Nieuwenhuizen •Wim C. J. Hop •Pauline Arends • Johan Boom . Johannes Jeekel • Johan F. Lange. Abdominal Wound Dehiscence in Adults: Developmentand Validation of a Risk Model.World J Surg (2010) 34:20–27.
[4]. Afzal S., Bashir M.M. Determinants of Wound Dehiscence in Abdominal Surgery in Public Sector Hospital. Annals vol14. NO. 3 jul-sept. 2008
[5]. Granam DJ, Stevenson JT, Mettenry CR. Association of intrabdominal infections and abdominal wound dehiscence. Am Surg 1998 Jul;64 (7):660-5..

Abstract: Purpose:In-vitro study to assess the effect of children's coloring beverages on resin modified glass ionomer and compomer in relation to microleakage, color stability, microhardness.
Materials and Methods: Microleakage was evaluated in eighty extracted primary molars, standard class V cavities were prepared on buccal surfaces of the teeth. They were randomly divided into two equal groups (n=40) according to tested materials. For color and microhardness assessment 160 disks were prepared using teflon mold, each disk was 5mm diameter and 2mm thickness. Disks divided into two groups each (n=80) according to type of restoration used.
Each group was divided into four subgroups regarding beverages used to: Water (subgroup A),Orange (subgroup B), Pepsi (subgroup C), Chocolate milk (subgroup D). Samples were immersed in beverages for 3 hours per day and the rest of the day in distilled water for 7 days. Microleakage test was assessed by dye penetration technique and observed under a stereomicroscope. For color values each specimen was measured using a portable Reflective spectrophotometer. Microhardness measurements was....

Key Word: compomer, resin modified glass ionomer, microleakage, color stability, microhardness

[1]. Yoonis E, Kukletová M. Tooth-colored dental restorative materials in primary dentition. Scripta Medica. 2009;82(2):108-14.
[2]. .Xavier AM, Sunny SM, Rai K, Hegde AM. Repeated exposure of acidic beverages on esthetic restorative materials: An in-vitro surface microhardness study. Journal of clinical and experimental dentistry. 2016;8(3):e312–e7.
[3]. Rios D, Honório HM, Francisconi LF, Magalhães AC, Machado MAdAM, Buzalaf MAR. In situ effect of an erosive challenge on different restorative materials and on enamel adjacent to these materials. Journal of dentistry. 2008;36(2):152-7.
[4]. Mali P, Deshpande S, Singh A. Microleakage of restorative materials: an in vitro study. Journal of Indian Society of Pedodontics and Preventive Dentistry. 2006;24(1):15-8.
[5]. Ren Y-F, Feng L, Serban D, Malmstrom HS. Effects of common beverage colorants on color stability of dental composite resins: the utility of a thermocycling stain challenge model in vitro. Journal of dentistry. 2012;40:e48-e56..

Abstract: Introduction: This study explored knowledge of vasectomy and its acceptance as a method of contraception among married males residing near RHTC of a tertiary care hospital in Amroha, UttarPradesh. Methods: A population based cross-sectional study was undertaken in a rural health training centre field practice area of a tertiary care hospital at Amroha from 1st August 2019 to 10th January 2020 using a pre-tested, self-administered questionnaire. Results: There were 250 male participants with a mean age of 32.6 ± 1.1 years. The largest proportion of respondents was from age group 31-35 (26%). The vast majority were Hindu (41%) followed by Buddhists (18%) & Muslims (17%). Out of total 250 married....

Key Word: Knowledge, acceptance, Married men, vasectomy, Public Health

[1]. Family welfare statistics in India, 29 August 2011 Statistics Division Ministry of Health and Family Welfare Government of India, National Rural Health Mission.
[2]. National Family Welfare statistics in India. Section – e; survey findings (nfhs, dlhs & facility survey)-Ministry of Health and Family Welfare, Government of India, 2009.
[3]. Akpamu U et al. Knowledge and acceptance of vasectomy as a method of contraception amongst literate married men in Ekpoma, Nigeria. Afr. J. Biomed. Res. 13 2010 May;153-156
[4]. Coulter A, Parsons S, Askham J. Where Are the Patients in Decision- Making About Their Own Care? Copenhagen, Denmark: WHO RegionalOffice for Europe; 2008.
[5]. A.Saoji et al. Denial mode for vasectomy among married men in Central India. Causes and suggested strategies. J Psychol Psychother 2013: 3(4).