iosr-JDMS   Volume-21 ~ Issue-4 ~ April 2022

Abstract: BACKGROUND: Diabetes Mellitus is a group of metabolic disease with increasing incidence every year with severe complications. The occurrence of ulcers in diabetic patients is the most common, attributed to the presence of thrombosis due to increased platelet function. Platelet volume indices (PVI) such as mean platelet volume (MPV), platelet distribution width (PDW), and platelet-large cell ratio (P-LCR) are the indicators of increased platelet activity and can be considered as potential biomarkers for diabetic complications. AIM To study PVI in Type 2 diabetics with and without diabetic ulcer in comparison to non diabetic patients. MATERIALS AND METHODS:......

Keywords: Diabetes, mean platelet volume, platelet distribution width and platelet large cell ratio, platelet volume indices

[1]. Whiting D R, Guariguata L, Weil C and Shaw J 2011 IDF diabetes atlas: global estimates of the prevalence of diabetes for 2011 and 2030 Diabet. Res. Clin. Pract. 3 11-21
[2]. Jabeen F, Fawwad A, Rizvi H A and Alvi F 2013 Role of platelet indices, glycemic control and hs-CRP in pathogenesis of vascular complications in type-2 diabetic patients Pak. J. Med. Sci. 29(1) 152-6
[3]. Waspadji S 2014 Kaki diabetes Buku ajar ilmu penyakit dalam vol 6, ed S Setiati, I Alwi, et al. (Jakarta: Interna Publishing) pp 2367-73
[4]. Citirik M, Beyazyildiz E, Simsek M, Beyazyildiz O and Haznedaroglu I C 2015 MPV may reflect subcinical platelet activation in diabetic patients with and without diabetic retinopathy Eye 29 376–9
[5]. Marshall SM, Barth JH. Standardization of HbA1c measurements – A consensus statement. Diabet Med. 2000;17:5–6. [PubMed] [Google Scholar].

Abstract: Objectives: The present study was conducted to assess patient characteristics and to determine Pulmonary Function impairments in treated sputum positive pulmonary tuberculosis patients. Also, to compare and correlate patient characteristics and pulmonary function derangements in such patients. Materials and methods: A prospective study was conducted on 30 patients visiting a tertiary care centre for treatment of tuberculosis. Newly diagnosed sputum positive PTB cases (age > 18 years) who completed 6 months of AKT and declared cured, were included and evaluated within 1 year duration of completion of their treatment Results: Total 30 patients were examined. 22 patients were males and 8 were females. 14 (47%) were found to have normal PFT while rest 16 (53%) had an abnormal......

Keywords: pulmonary function test, obstruction ,restriction ,dyspnoea , Endobrochial

[1]. WHO India (2012). Core Programme Clusters, Communicable diseases and disease surveillance. Tuberculosis. http://www.whoindia.org/en/section3/section123.htm (accessed on 21/11/21).
[2]. S K Verma et al. A Study on Prevalence of Obstructive Airway Disease among Post Pulmonary Tuberculosis Patients. Pulmon. 2009;11(1):4- 7.
[3]. S.K. Verma et al. Post Tubercular Obstructive Airway Impairment', Indian Journal of Allergy Asthma and Immunology. 2009;23(2):95-99
[4]. Tada A, Matsumoto H, Soda R, Endo S, Kawai H, Kimura G et al. Effects of pulmonary rehabilitation in patients with pulmonary tuberculosis sequelae. Nihon KokyukiGakkaiZasshi (2002 Apr);40(4):275-81.
[5]. Baig IM, Saeed W, Khalil KF. Post-tuberculous chronic obstructive pulmonary disease

Abstract: Juvenile ossifying fibroma is a benign fibro-osseous lesion.1 Ossifying fibromas are of two types, the central type and peripheral type. Central ossifying fibroma is also of two types, conventional type and juvenile type. 2Juvenile ossifying fibroma (JOF) is a locally aggressive variant of central ossifying fibromas of the jaws, and it has a high tendency of recurrence with more common in young ones.2 Lesion found both in maxilla and mandible,most commonly in maxilla,paranasal sinus and sometimes orbit. It rarely involves mandible.3 It mostly affects the children less than 15 years of age.3 On the basis of histopathology,it is of 2 types psammamatoid and trabecular.3 This article reports a rare case of young adult who presented with a benign lesion in floor of mouth of mandible.

[1]. Sarah Lemoine; Elisabeth Cassagnau; Hélios Bertin; Maria Poisson; Pierre Corre; Julien Guiol(2017). Juvenile ossifying fibroma: case report and literature review.Management and differential diagnosis.journalof oral med oral surgery,24,67-71.
[2]. Kundu PR, Beniwal K, Singh B, Kaur S. Juvenile ossifying fi broma: An unusual case report and review of the literature.
Saudi Surg J 2014;2:57-9. [3]. Khanna J;Ramaswami R(2018).Juvinle ossifying fibroma in mandible.Annals of maxillofacial surgery,8(1),147-150.
[4]. Sondos Abuzinad; Alyamani A2 (2009) Management of juvenile ossifying fibroma in the maxilla and mandible. J Maxillofac Oral Surg 9(1):91-95 [5]. Riitta Leimola-Virtanen; Kimmo Vähätalo; Stina Syrjänen (2001). Juvenile active ossifying fibroma of the mandible: A report of 2 cases. , 59(4), 439–444.

Abstract: BACKGROUND- We wanted to compare the success rate of classical supraclavicular approach of brachial plexus block with and without a nerve stimulator. METHODS- A prospective, randomized, comparative study was conducted at department of anaesthesiology , ACSR Govt Medical college on 100 ASA I, II patients aged between 18 to 60years posted for elective upper limb surgeries, during the period of November 2020 to February 2022 ,by dividing the patients in to two groups RESULTS-The comparision between paraesthesia technique and use of nerve stimulator in performing supraclavicular brachial plexus block with respect to onset of sensory and motor blockade was significantly faster with the nerve stimulator technique.Duration of block was longer with the nerve stimulator technique,Total duration of block was more with Nerve stimulator technique as compared to Paraesthesia technique (7.28 hrs vs 6.54 mins; p-0.057).......

Keywords: PNS-Peripheral nerve stimulation ,SC Block-Supraclavicular block

[1]. Moore D: Supraclavicular approach for block of the brachial plexus, in Moore D(ed): Regional block. A handbook for use in the clinical practice of medicine and surgery, 4th ed. Springfield, Charles C Thomas Publisher, 1981; pp 221-41.
[2]. Labat G: Regional anaesthesia. Its technic and clinical application. Philadelphia, W.B. Saunders Company, 1922.
[3]. Kulenkampff D, Persky M. Brachial plexus anaesthesia. Its indications, technique and dangers. Ann Surg 1928;87:883-91
[4]. Winnie AP. Historical consideration.Chapters 2 and 4.Plexus Anaesthesia. New York: Churchill Livingstone 1984;1:43-116,192-202.
[5]. Liguori GA, Zayas VM, Ya Deau JT. Nerve localisation techniques for interscalene brachial plexus blockade: a prospective, randomised comparison of mechanical paresthesia versus electrical stimulation.

Abstract: INTRODUCTION: Management of condylar fractures had generated great deal of discussion and controversy than any other fields of maxillofacial trauma. Condylar fractures account for a total of 25% to 35% of all the mandibular fractures. The current scenario of management of condylar fractures had moved towards open reduction and internal fixation by using different plating systems. Single and two miniplates placed along the fractured condyle could not totally neutralise the dynamic osteosynthesis of the condyle which showed the way towards the usage of three dimensional plating system. Diminution of micro movements between implant and the bone interface increases the implant stability which lead to the shift of era towards the locking plates.......

Keywords: condyle fracture, dynamic osteosynthesis, delta plate, locking plate.

[1]. Manoj Chaudhary, Harshvardhan Pant. Evaluation of trapezoidal- shaped 3D plates for internal fixation of mandibular sub condylar fractures in adults, journal of oral biology and craniofacial research 2015, Sep-Dec; 5(3): 134–139.
[2]. Soichiro Ibaragi1 , Norie Yoshioka1 , Koji Kishimoto1 , Akira Sasaki Endoscope-Assisted Transoral Reduction and Internal Fixation of a Mandibular Subcondylar Fracture with a 3D - Shaped Plate International Journal of Contemporary Medical Research ISSN 2393-915X; 2454-7379 | ICV (2015): 77.83
[3]. Ellis E 3rd , Graham J. Use of a 2-00mm locking plate/ screw system for mandibular fracture surgery. J oral and maxillofac surg. 2002;60:642-5.
[4]. Niezen ET, Bos RRM, van Minnen B, Eckelt U, Tavassol F, et al. Fractures of the mandibular condyle: a comparison of patients, fractures and treatment characteristics between Groningen (The Netherlands) and Dresden (Germany). J Craniomaxillofac Surg 2018;46:1719-25.
[5]. B. Edwards ∗, E. Burke, C. Fowell The incidence and pattern of mandibular fractures in a United Kingdom Regional Trauma units journal of oral and maxillofacial surgery. ijoms 2017.02.874

Abstract: Chronic Kidney Disease (CKD) is a global health issue with a rising incidence and prevalence. In individuals with Chronic Kidney Disease, abnormalities in the structure and function of the thyroid gland, as well as the metabolism and plasma levels of thyroid hormones, are common. Because thyroid function tests in patients with CKD have been inconsistent in prior research, a prospective investigation of various thyroid functions is being conducted to see if there is a link between thyroid malfunction and the severity of renal disorders. Method: A prospective study was carried out on 50 patients with chronic kidney disease who were being treated conservatively. The Enzyme Linked Immunosorbent Assay was used to measure T3, T4, and TSH quantitatively, and the results were examined.......

[1]. Andrew S. Levey, Josef Coresh, Ethan Balk, Annamaria T. Kausz, Ronald D. Perrone. National Kidney Foundation Practice Guidelines for Chronic Kidney Disease: Evaluation, Classification, and Stratifiction. MD Ann Intern Med. 2003;139:137-147.
[2]. Joanne M.Bargman, Karl S.Korecki. Chronic kidney disease. In: Dan L.Lango, Anthony S.Fauci, Dennis Kasper et al. Harrison's Principles of Internal Medicine, Vol. 2, 18th edn., 2011; McGraw Hill, USA, pp. 2289-2293; 2308-2313.
[3]. Feinstein EI, Kaptein EM, Nicoloff JT &Massry SG. Thyroid function in patients With nephrotic syndrome and normal renal Function. American Journal of Nephrology 1982 2 70-76.
[4]. Kaptein EM, Quion-Verde H &Massry SG. Hemodynamic effects of thyroid Hormone. Contributions to Nephrology 1984 41 151-159.
[5]. Kaptein EM. Thyroid function in renal Failure. Contributions to Nephrology 1986 50 64-72.

Abstract: Palato gingival groove (PGG) is an extremely unusual developmental defect that is most commonly present on the palatal surface of maxillary teeth. PGG forms as the central fossa passes the cingulum and persists in an apical axis for variable distances. The flaw is hidden from cleaning attempts and provides an ideal environment for plaque or calculus to accumulate. If the issue is not addressed, it can lead to a slew of periodontal problems, including attachment loss, pocket formation, and progressive bone loss. Clinicians must choose a way to eradicate the causal pathologic cause and obtain a favourable outcome from the different therapeutic alternatives available. A unique approach for the management of PGG is described in this case report. It is a trustworthy alternative that provides proper physiology, anatomy, and quality of life while delivering satisfactory results.

Keywords: Endodontic, Palato gingival groove, Modified reimplantation, SynOss putty

[1]. Lee KW, Lee EC, Poon KY. Palato-gingival grooves in maxillary incisors. A possible predisposing factor to localised periodontal disease. Br Dent J 1968;124(1):14-8.
[2]. Ennes JP, Lara VS. Comparative morphological analysis of the root developmental groove with the palato-gingival groove. Oral Dis 2004;10(6):378-82.
[3]. Simon JH, Glick DH, Frank AL. Predictable endodontic and periodontic failures as a result of radicular anomalies. Oral Surg Oral Med Oral Pathol 1971;31(6):823-6.
[4]. Bose BB, Sudarsan S. Palatogingival groove – An added dimension in the etiology of localised periodontitis. Int J Dent Sci Res 2013;1(1):5-7.
[5]. Gao ZR, Shi JN, Wang Y, Gu FY. Scanning electron microscopic investigation of maxillary lateral incisors with a radicular lingual groove. Oral Surg Oral Med Oral Pathol 1989;68(4):462-6.

Abstract: Root canal therapy has enabled us to save numerous teeth over the years. Revitalizing a tooth with diseased pulp or nonvital tooth will be the most desired outcome of any endodontic treatment.Tissues are organized as three-dimensional structures, and appropriate scaffolding is necessary to provide a spatially correct position of cell location and regulate differentiation, proliferation, or metabolism of the stem cells. Extracellular matrix molecules control the differentiation of stem cells. Regeneration of different tissues are facilitated by different scaffolds. An appropriate scaffold selectively localizes, bind cells and contain growth factors. Scaffolds undergo biodegradation over time. Thorough and precise knowledge about the suitable scaffold for the required tissue is needed for successful regeneration. The current review presents how for dentin–pulp complex regeneration, the application of fibrin scaffolds could represent a promising approach.

Key Words: Regeneration, Stem cells, Growth factors, Fibrin Scaffolds, Hydrogel

[1]. Bekhouche M, Bolon M, Charriaud F, Lamrayah M, Da Costa D, Primard C, Costantini A, Pasdeloup M, Gobert S, Mallein-Gerin F, Verrier B. Development of an antibacterial nanocomposite hydrogel for human dental pulp engineering. Journal of Materials Chemistry B. 2020;8(36):8422-32.
[2]. Mao JJ, Kim SG, Zhou J, Ye L, Cho S, Suzuki T, et al. Regenerative endodontics: Barriers and strategies for clinical translation. Dent Clin North Am.2012;56:639–49.[PMCID: PMC4093795][PubMed:22835543]
[3]. Moussa DG, Aparicio C. Present and future of tissue engineering scaffolds for dentin‐pulp complex regeneration. Journal of tissue engineering and regenerative medicine. 2019 Jan;13(1):58-75.
[4]. Abbass M, El-Rashidy AA, Sadek KM, Moshy SE, Radwan IA, Rady D, Dörfer CE, Fawzy El-Sayed KM. Hydrogels and Dentin–Pulp Complex Regeneration: From the Benchtop to Clinical Translation. Polymers. 2020 Dec;12(12):2935.
[5]. Fahmy, S.H.; Hassanien, E.E.S.; Nagy, M.M.; El Batouty, K.M.; Mekhemar, M.; Fawzy El Sayed,K.;Hassanein, E.H.; Wiltfang, J.; Dorfer, C. Investigation of the regenerative potential of necrotic mature teeth following diff erent revascularisation protocols. Aust. Endod. J. 2017

Abstract: Aims and objectives There is a paucity of Indian studies on clinic-pathological profile and long-term relapse rates of Non-Hodgkin`s lymphoma (NHL). Hence this study was undertaken to assess the clinic-pathological profile & relapse rates in NHL. Methods All newly diagnosed patients of NHL from 2017 to 2019 were enrolled in the study. The data was collected prospectively after due IEC clearance. The patients were interviewed using predesignate standardized proforma fully vetted by medical education faculty. Clinical details of pallor, icterus, lymphadenopathy, bulky lymph nodal mass, hepatomegaly, or splenomegaly were examined. These patients underwent a hemogram and findings of peripheral blood smear were noted. Liver function tests, renal function tests, serum electrolytes, serum uric acid, serum LDH, HIV, HBsAg, Anti HCV Ab serology.......

Keywords: Non-Hodgkin`s lymphoma, clinic-pathological profile, PET, flow cytometry, biopsy, relapse rate.

[1]. Nair R, Arora N, Mallath MK. Epidemiology of non-Hodgkin's lymphoma in India. Oncology. 2016;91(Suppl. 1):18-25. [2]. Jaffe ES, Harris NL, Stein H, Isaacson PG. Classification of lymphoid neoplasms: the microscope as a tool for disease discovery. Blood, The Journal of the American Society of Hematology. 2008 Dec 1;112(12):4384-99 [3]. Jaffe ES, Harris NL, Stein H, Vardiman JW. World Health Organization Classification of Tumours: Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. Vol 3, 3rd ed. Lyon: IARC; 2001.submit your manuscript | www.dovepress.comDovepress Dovepress265Treatment of relapsed/refractory non-Hodgkin's lymphomaCancer Management and Research downloaded from https://www.dovepress.com/ by 42.109.228.49 on 25-Jul-2021For personal use only.Powered by TCPDF (www.tcpdf.org) [4]. Chen Y, Han T, Iqbal J, Irons R, Chan WC, Zhu X, et al. Diffuse large B-cell lymphoma in Chinese patients. Am J Clin Pathol. 2010;133(2):305–13.
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Abstract: Diverticulum of the lacrimal sac is a rare condition characterized by an outpouching of the lacrimal sac. It could be congenital, inflammatory or post-traumatic. Herein management of a case of a 13 year old boy who presented with 8 months history of swelling in the left lacrimal region associated with epiphora diagnosed as lacrimal sac diverticulum is reported. The need for careful evaluation of masses arising from the lacrimal region and consideration of rare conditions such as lacrimal sac diverticulum as a differential diagnosis is highlighted.

Key words : Lacrimal sac, diverticulum, epiphora

[1]. Chakraborti C, Barua N, Chishti K R, Kumar S. A rare case of lacrimal sac diverticulum associated with rhinosporidosis. J Clin Ophthalmol Res 2017; 5: 97 – 100.
[2]. Ali M J. Naik M N. congenital lacrimal sac diverticulum. Saudi Journal of Ophthalmology 2017;31:199 – 200.
[3]. Ormrod JN. Diverticulum of the lacrimal sac. Br J Ophthal 1958; 42: 526 – 528.
[4]. Zhang C, Wu Q, Yu J, Cui Y, Cao W, et al. Lacrimal Sac Diverticulum Presenting as a Lower Eyelid Mass with a Secreting Fistula. J Clin Exp Ophthalmol 2013; 4: 310 – 313.
[5]. Ali MJ, Kakizaki H. Embryology of the lacrimal drainage system: In Principles and practice of lacrimal surgery. Springer India 2015; Chp 2: Pg 14.

Abstract: Objective: This study aimed to compute the heart rate and patients' anxiety in Saudi patients during an oral surgical procedure. Methods: A male referral patients (N=20) for 3rd molar extraction who were recruited with their written consent. Inclusion criteria' a need for surgical 3rd molar extraction, negative medical history, low to high-income status, free of medical drugs, age 18-45 years,. Before the start of the surgical procedure, a video demonstration was given to the participants. Heartbeat and dental fear were recorded at distinct intervals namely in the waiting area, sitting on the dental chair, surgical incision, bone drilling, tooth extraction, suturing and in the postoperative area.......

Keywords: 3rd Molar extraction, Dental anxiety, Heartbeat

[1]. Domschke K, Stevens S, P fleiderer B, Gerlach AL Interoceptive sensitivity in anxiety and anxiety disorders: an overview and integration of neurobiological findings. Clin Psychol Rev 2010; 30:1-11 [2]. Tsunoda T, Yoshino A, Furusawa T, Miyazaki M, Takahashi Y, Nomura S. Social anxiety predicts unconsciously provoked emotional responses to facial expression. Physiol Behav 2008; 93:172–6
[3]. Milgrom P, Newton J T, Boyle C, Heaton L J, Donaldson N. The effects of dental anxiety and irregular attendance on referral for dental treatment under sedation within the National Health Service in London. Community Dent Oral Epidemiology 2010; 38:453–9.
[4]. Serra-Negra J, Paiva S M, Oliveira M, Ferreira E, Freire-Maia F, Pordeus I. Self-reported dental fear among dental students and their patients. Int J Env Res Pub Health 2012;9:44–54
[5]. de Jongh A, Schutjes M, Aartman I H A. A test of Berggren's model of dental fear and anxiety. Eur J Oral Sci 2011; 119:361–5.

Abstract: Background: Inguinal hernia is defined as an abnormal protrusion of the contents of the abdominal cavity or preperitoneal fat through a defect in the inguinal area. The tissue-based techniques are still acceptable for primary inguinal hernia repair according to the European Hernia Society guidelines. In 2001, Desarda described a new method which is a tissue-based hernia repair using an undetached strip of external oblique aponeurosis to build up strength of the posterior wall of the inguinal canal. Objective: To compare the early clinical outcomes of the tissue-based Desarda Technique with Lichtenstein mesh-based repair. Methods: A total of 60 patients were randomly allocated into two groups i.e., Desarda and Lichtenstein.......

Keywords: Desarda repair, Inguinal hernia, Lichtenstein repair, Recurrence

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