iosr-JDMS   Volume-23 ~ Issue-6 ~ June 2024

Abstract: La tuberculose représente un problème majeur de santé publique dans le monde. Elle est responsable de 10 millions de nouveaux cas dans le monde en 2022 et 1,5 million de décès. Son incidence au Maroc en est de à 93/10-5 habitant. La tuberculose une maladie infectieuse évitable et guérissable sous réserve d'un traitement bien conduit et prolongé associant plusieurs antituberculeux. Ce traitement antituberculeux a permis....

[1] Fekih L, Fenniche S, Boussoffara L, Et Al. Manifestations D'hypersensibilité Aux Antituberculeux. Rev Mal Respir 2010; 27: 673-678.
[2] Bévilacqua S, Rabaud C, May T.HIV-Tuberculosis Coinfection. Ann Med Intern 2000; 153: 113- 8.
[3] Gruchalla R. Understanding Drug Allergies. J Allergy Clin Immunol 2000; 105:S634-7.
[4] Ormerod LP, Horsfield N. Frequency And Type Of Reactions To Antituberculosis Drugs: Observations In Routine Treatment. Tuberc Lung Dis 1996; 77: 7-42.5.
[5] Matz T, Borish LC, Routes JM, Rosenwasser LJ. Oral Desensitization To Rifampicin And Ethambutol In Mycobacterial Disease. Am J Respir Crit Care Med 1994; 149: 815 -7.

Abstract: Resume La rifampicine est un antibacillaire majeur, pouvant induire des réactions toxiques dose dépendantes ou des réactions immunoallergiques. La thrombopénie induite par la rifampicine est un effet immunoallergique bien connu mais qui reste rare. Nous présentons ici deux observations de thrombopénie immunoallergique à la rifampicine. Le premier cas est celui d'une femme de 32 ans, présentant une miliaire tuberculeuse, et rapportant 3 semaines après le début d'un traitement par isoniazide, rifampicine, pyrazinamide et éthambutol, des lésions cutanées purpuriques généralisées sans syndrome hémorragique extériorisé. La numération formule sanguine a objectivé une thrombopénie......

[1] Conférence D'expert De La SPLF. Recommandations De La Société De Pneumologie De Langue Française Pour La Prise En Charge De La Tuberculose En France. Rev. Mal. Respir. 2004 ; 3S3–104.
[2] B. Flageul, L. Wagner And F. Cottenot, Accidents Immunoallergiques A La Rifampicine, Acta Leprol. 12 (2001/2002) (2), Pp. 71–78.
[3] Thrombopénie Immunoallergique A La Rifampicine : A Propos D'un Cas. Revue Française d'Allergologie Et d'Immunologie Clinique Volume 46, Issue 7, Novembre 2006, Pages 656-658[4]
L. Cheng-Huei And L. Ching-Jyh, Thrombocytopénia –– A Rare But Potentially Serious Side Effect Of Initial Daily And Interrupted Use Of Rifampicin, Chest 9 (1989) (1), Pp. 202–203.
[5] Y. Mehta, F. Jijina, S. Badakere, A. Pathare And D. Mohanty, Rifampicin-Induced Immune Thrombocytopenia, Tuber. Lung Dis. 77 (1996), Pp. 558–562.

Abstract: La sarcoïdose est une maladie systémique d'étiologie inconnue, dont les manifestations cliniques sont très diverses et pouvant intéresser plusieurs organes avec une prédominance de l'atteinte médiastino-pulmonaire. La prévalence de la thrombopénie au cours de la sarcoïdose n'est pas connue. Des observations isolées sont rapportées. En 1938, Jersild et al. [1] ont été les premiers à signaler la survenue d'une thrombocytopénie dans la sarcoïdose. Cependant, à notre connaissance, moins d'une centaine de cas sont rapportés dans la littérature. Trois mécanismes sont évoqués, un hypersplénisme, un envahissement médullaire par des granulomes ou un mécanisme immunologique......

[1] Jersild M. Le Syndrome De Heerfordt (Fièvre Uvéo-Parotide), Manifestation Du Sarcoïde De Boeck. Acta Med Scand . 1938;97 : 322-328.
[2] Mahevas M, Le Page L, Salle V, Lescure Fx, Smail A, Cevallos R, Garidi R, Marolleau Jp, Duhaut P, Ducroix Jp. Thrombocytopénie Dans La Sarcoïdose. Sarcoïdose Vasculaire Pulmonaire Diffuse . 2006;23 : 229-235.
[3] Mahévas, Matthieu Md; Chiché, Laurent Md; Uzunhan, Yurdagul Md; Khellaf, Medhi Md ; Morin, Anne-Sophie Md; Le Guenno, Guillaume Md; Péronne, Véronique Md; Affo, Louis Md; Lidove, Olivier Md; Boutboul, David Md; Dion, Geneviève Md; Ducroix, Jean-Pierre Md; Papo, Thomas Md, Phd; Pacheco, Yves Md; Schleinitz, Nicolas Md, Phd; Michel, Marc Md, Phd; Godeau, Bertrand Md, Ph.D.; Valeyre, Dominique Md .Association De Sarcoïdose Et De Thrombocytopénie Immunitaire : Présentation Et Résultat Dans Une Série De 20 Patients. Médecine 90(4):P 269-278, Juillet 2011. | Doi : 10.1097/Md.0b013e31822618b3
[4] Fordice J, Katras T, Jackson Re, Cagle Pt, Jackson D, Zaleski H, Asimacopoulos Pj. Splénomégalie Massive Dans La Sarcoïdose. Sud Med J . 1992;85 : 775-778.
[5] Madaule S, Lauque D, Sailler L, Arlet P, Carles P. [Splénomégalie Dans La Sarcoïdose : Caractéristiques Cliniques Et Evolution. Analyse De 17 Cas. Rév Med Interne . 2004;25:348-356.

Abstract: Background: The era of science and technology has evolved to such an extent that the use of dental materials tends to miniaturised itself in the past few decades and rest to come. From macromolecules to micromolecules and thereafter nanomolecules has proved to dictate the evolution of dental materials and technology an everlasting phenomenon. The present paper dictates the role of nanotechnology by using miniaturised forms such as nanofibers, nanorobotics, nanodrugs delivery systems, nanoparicles and how it acts at a nanolevel which proves to be advantageous in different conditions. At this way certain challenges which has been faced previously can now be resolved at a nanolevel.....

Keywords: Microorganism, local drug delivery, nanofibers, nanorobotics

[1] Narayanan Mba, Kumar Sgr, Jayanthi D. Nanodentistry-An Overview. Jiaphd. 2011(18):278-81
[2] Kong Lx, Peng Z, Li Sd, Bartold Pm. Nanotechnology And It's Role In The Management Of Periodontal Diseases. Periodontology. 2000;40:184-196
[3] Karczewski A, Feitosa Sa, Hamer Ei, Pankajakshan D, Gregory Rl, Spolnik Kj, Bottino Mc. Clindamycin Modified Triple Antibiotic Nanofibers-A Stain Free Antimicrobial Intracanal Drug Delivery System. J Endod. 2018 January; 44(1):155-162
[4] Parhizkar A, Asgary S. Local Drug Delivery Systems For Vital Pulp Therapy: A New Hope. Hindawi. 2021:1-9
[5] Park B. Current And Future Applications Of Nanotechnology. Issues In Environmental Science And Technology. 2007;24:1-18

Abstract: Pulmonary candidiasis is a rare entity predominant in immunosuppressed patients , its true incidence ranges from 0.23% to 0.4%. Its occurrence in immunocompetent patients has been rarely described in the literature and its diagnosis is mainly based on bronchoalveolar lavage We report a rare case of pulmonary candidiasis in an immunocompetent patient.

[1] B. Ourari-Dhahri, J. Ben Amar , L. El Gharbi, M.A. Baccar, S. Azzabi,H. Aouina, H. Bouacha : Lung Mycosis In Non Neuropenic Patients ,Journal De Mycologie Médicale,Volume 22, Issue 3, September 2012, Pages 217-220
[2] Durga Shankar Meena Deepak Kumar , Candida Pneumonia: An Innocent Bystander Or A Silent Killer? Med Princ Pract 2022;31:98–102 Doi: 10.1159/000520111
[3] Masur H, Rosen Pp, Armstrong D. Pulmonary Disease Caused By Candida Species. Am J Med. 1977 Dec; 63(6): 914–25.
[4] Haron E, Vartivarian S, Anaissie E, Dekmezian R, Bodey Gp. Primary Candida Pneumonia.Experience At A Large Cancer Center And Review Of The Literature. Medicine. 1993; 72:137–42.
[5] Kumamoto Ca, Vinces Md. Alternative Candida Albicans Lifestyles: Growth On Surfaces. Annu Rev Microbiol. 2005; 59: 113–33.

Abstract: Background – alcohol is one of the most widely consumed substances, and its effects include alterations in the complete blood count (cbc). The primary factors causing these changes in cbc are: myelosuppression , which leads to a slight reduction in all blood cell types, gastrointestinal bleeding, and malnutrition. Individuals with alcoholism may experience moderate anemia, marked by enlarged and structurally abnormal red blood cells (rbcs); a slight decrease in white blood cells (wbcs), particularly neutrophils; and a moderate to severe reduction in platelets......

Keywords: alcoholics, hematological manifestations, non alcoholics

[1] National Council On Alcoholism And Drug Dependence Wikipedia, The Free Encyclopaedia (Citied Oct. 2009) Available From Http: Wikipedia.Org/Alcoholism
[2] Robert M. Morse, Md; Daniel K. Flavin, Md, The Definition Of Alcoholism Jama. 1992;268(8):1012-1014. Vol. 268, No. 22, Aug. 1992 3.
[3] History Of Alcoholic Beverages From Wikipedia, The Free Encyclopaedia
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[5] The Hindu Dated 3 Rd May 2008. Www.Thehindu.Com/2008/05/03/....Html

Abstract: Xeroderma pigmentosum (XP) is a rare genetic disease characterized by hypersensitivity to ultraviolet (UV) radiation due to a defect in DNA repair. While the increased risk of skin cancer is well documented, ocular manifestations of this disease are less common but can have a significant impact on the quality of life of patients. This article presents retrospective study of 40 eyes of Moroccan patients with XP and significant ocular involvement, highlighting the importance of awareness, prevention, early detection, and interdisciplinary collaboration.

Keywords: xeroderma, pigmentusum, ocular , eyelid, conjonctival

[1] Kraemer Kh, Lee Mm, Scotto J: Xeroderma Pigmentosum. Cutaneous, Ocular, Neurologic, Abnormalities In 830 Published Cases. Arch Dermatol 1987;123:241–250.
[2] Laura J. Niedernhofer. Tissue Specific Accelerated Aging In Ner Deficiency. Mecanisms Of Ageing And Development 2008; 129: 408-415.
[3] Zghal M, Fazaa B, Kamoun M R. Xéroderma Pigmentosum. Elsevier Masson (2006): 1-20
[4] B. Fazaa, M.R. Kamoun. Xéroderma Pigmentosum. Ann Dematol Venereol 2003; 130: 69-73
[5] Rouberol F. Et Col. Epithélioma Conjonctival Chez Un Enfant De Neuf Ans Porteur D'un Xéroderma Pigmentosum. J Fr. Ophtalmol. Masson,2001; 24, 6, 639-642

Abstract: Introduction: Abdomen being the third most commonly injured organ, represents 20% of the injuries requiring operative intervention. Despite being frequent, the recognition and treatment of life threatening intra-abdominal injuries remains a challenge, and 10% of all traumatic deaths are the direct consequence of abdominal injuries. There is very little room for error and well co-ordination of surgical, laboratory and radiological skill is the key to manage the patients with penetrating abdominal trauma. Materials and Methods.....

Keywords: Penetrating abdominal trauma, Exploratory laparotomy, Bowel perforation

[1] Minino Am, Heron Mp Ms. Deaths : Final Data For 2004. Natl Vital Stat. 2007;55(19):1–120.
[2] Butt Mu, Zacharias N, Velmahos Gc. Penetrating Abdominal Injuries: Management Controversies. Vol. 17, Scandinavian Journal Of Trauma, Resuscitation And Emergency Medicine. 2009.
[3] Como Jj ,Bokhari F Cw. Practice Management Guidelines For Selective Non Operative Management Of Penetrating Abdominal Trauma. J Trauma. 2010;68(3):721–33.
[4] Schroeppel Tj Cm. Diagnosis And Management Of Blunt Abdominal Solid Organ Injury. Curr Opin Crit Care Curr Opin Crit Care. 2007;13(4):399–404.

Abstract: Eruption failure of the first permanent molar is very rare; the incidence is 0.01% of the population. Adequate occlusal support and facial growth coordination is provided by permanent molars. Failure to erupt leads to an array of complications. It is imperative to diagnose and manage the condition at initial stage. Deeply impacted mandibular first molar cases, the extraction needs delicate technique and in addition requires cautious management to diminish risks of injury to the adjacent teeth, neurovascular bundle and the mandibular fracture. This report summarizes a rare case of impacted mandibular molar treated surgically in a unique way, where in the socket and nerve preservation were carried out simultaneously.

Keywords: Impacted first molar, Nerve preservation, Socket grafting

[1] Management Of Impacted Permanent First Molar-A Case Report Bhawana A Bhagat 1 (Mds), Arun P Nagrik 2 (Mds), Sushil B Yemle 3 (Mds). Available From: Www.Iosrjournals.Orgwww.Iosrjournals.Org
[2] Sonpal Pm, Mundada Bp, Bhola Nd, Kamble R, Mathew J. Impacted Mandibular First Molar: A Rare Riddle. Cureus. 2022 Nov 20

Abstract: Ocular coloboma is due to failure of the closure of the embryonic fissure. It can be can be sporadic, hereditary or associated with chromosomal abnormalities. We present a 12-year-old child diagnosed with unilateral iridochoroidal, crystalline and eyelid coloboma who was referred to our department for a full ocular examination. Ocular coloboma is a rare condition. It is generally located in the inferonasal quadrant. there are some physiopathological hypotheses, but but they are controversial. Treatment is most often conservative. Ocular coloboma is a unique congenital condition that can involve many ocular structures. Early screening helps prevent possible complications.

Keywords: iridochoridal- crsystalline- eyelid-coloboma -child

[1] Nezzar H, Chiambaretta F, Rigal D, Et Al. L'iris Et Sa Pathologie. Rapport Annuel Des Sociétés De Paris. Novembre Marseille: Lamy (2003). 65-80
[2] Duvall J, Miller SL, Cheatle E, Tso MO. Histopathologic Study Of Ocular Changes In A Syndrome Of Multiple
[3] Pederna E, Méndez C. Embriología En La Clínica. Casos Médicos. 2006;21:125–7
[4] Shaheen P. Shah; Amy E. Taylor; Jane C. Sowden; Nicola K. Ragge; Isabelle Russell-Eggitt; Jugnoo S. Rahi; Clare E. Gilbert; For The Surveillance Of Eye Anomalies (SEA-UK) Special Interest Group Anophthalmos, Microphthalmos, And Typical Coloboma In The United Kingdom: A Prospective Study Of Incidence And Risk
[5] Morrison D, Fitzpatrick D, Hanson I. National Study Of Microphthalmia, Anophthalmia, And Coloboma (MAC) In Scotland: Investigation Of Genetic Aetiology. J Med Genet. 2002;39:16–22

Abstract: Les valvulopathies sont l'une des principales causes de morbi-mortalité cardiovasculaires dans le monde avec une répartition géographique diversifiée et évolutive [1]. Les cardiopathies rhumatismales restent la cause la plus fréquente de valvulopathie dans le monde et plus précisément dans les pays en voie de développement et touchent environ 41 millions de personnes [1]. Dans les pays développés, ces valvulopathies sont liées essentiellement à la pathologie dégénérative en rapport avec le vieillissement de la population, la prévalence de........

[1] Aluru, J.S., Barsouk, Adam, Saginala, K., Rawla, P., Barsouk, Alexander, 2022. Valvular Heart Disease Epidemiology. Med Sci (Basel) 10, 32. Https://Doi.Org/10.3390/Medsci10020032
[2] Berti, S., Bonanni, M., D'agostino, A., Celi, S., Mariani, M., 2023. Treatment Of Multiple Valve Disease: Surgery, Structural Intervention, Or Both? Eur Heart J Suppl 25, B21–B24. Https://Doi.Org/10.1093/Eurheartjsupp/Suad061
[3] Vahanian, A., Himbert, D., Brochet, E., 2015. Multiple Valve Disease - Assessment, Strategy And Intervention. Eurointervention 11 Suppl W, W14-16. Https://Doi.Org/10.4244/Eijv11swa3
[4] Vahanian, A., Beyersdorf, F., Praz, F., Milojevic, M., Baldus, S., Bauersachs, J., Capodanno, D., Conradi, L., De Bonis, M., De Paulis, R., Delgado, V., Freemantle, N., Gilard, M., Haugaa

Abstract: Traumatic finger amputations are the most commonly encountered forms of partial hand loss. The prosthetic rehabilitation of an amputated finger is considered when micro-surgical reconstruction is contraindicated, unaffordable or failed. An aesthetic and functional prosthesis can offer distinct psychological and rehabilitative advantages to the patient. This article presents rehabilitation of a young male patient with amputated right ring finger by fabrication of an aesthetic silicone finger prosthesis retained by a dental implant, osseointegrated over a period of four months. The type of attachment was a custom designed ball abutment attached to a telescopic housing carrying an O-ring. An.....

Keywords: Abutment Design; Amputation; Dental Implant; Finger Prosthesis; Surgical Flap

[1]. Aydin C, Karakoca S, Yilmaz H. Implant-Retained Digital Prostheses With Custom-Designed Attachments: A Clinical Report. J Prosthet Dent. 2007 Apr 1;97(4):191–5.
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[4]. Kini Ay, Byakod Pp, Angadi Gs, Pai U, Bhandari Aj. Comprehensive Prosthetic Rehabilitation Of A Patient With Partial Finger Amputations Using Silicone Biomaterial: A Technical Note. Prosthet Orthot Int. 2010 Dec;34(4):488–94.
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Abstract: Confounding factors, including preferences for coronary target grafting, reconstruction procedures, medication regimens, patient variances, and post-operative time limit direct comparisons of coronary bypass conduits. Certain aspects of a patient, such as age, gender, drugs, or coexisting conditions, should have an equivalent impact on conduits. When comparing conduits in a group setting, bias is minimized when all patients receive all three comparison conduits, as opposed to some patients receiving only one or none. This study aims at reviewing.....

Keywords: conduits in CABG, radial artery conduits, radial artery and LIMA, radial artery and other autologous conduits, coronary artery revascularization

[1] A. Carpentier, J. L. Guermonprez, A. Deloche, C. Frechette, And C. Dubose, "The Aorta-To-Coronary Radial Artery Bypass Graft: A Technique Avoiding Pathological Changes In Grafts," The Annals Of Thoracic Surgery, Vol. 16, No. 2, Pp. 111–121, 1973.
[2] A. S. Geha, R. J. Krone, J. R. Mccormick, And A. E. Bauer, "Selection Of Coronary Bypass: Anatomic, Physiological, And Angiographic Considerations Of The Vein And Mammary Artery Grafts," The Journal Of Thoracic And Cardiovascular Surgery, Vol. 70, No. 3, Pp. 414–431, 1975.
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[4] C. Acar, A. Ramsheyi, J.-Y. Pagny, Et Al., "The Radial Artery For Coronary Artery Bypass Grafting: Clinical And Angiographic Results At Five Years," The Journal Of Thoracic And Cardiovascular Surgery, Vol. 116, No. 6, Pp. 981–989, 1998.
[5] P. Achouh, R. Boutekadjirt, D. Toledano, Et Al., "Long-Term (5- To 20-Year) Patency Of The Radial Artery For Coronary Bypass Grafting," The Journal Of Thoracic And Cardiovascular Surgery, Vol. 140, No. 1, Pp. 73–79.E2, 2010

Abstract: The quest for an appealing smile holds significant importance in today's competitive society, impacting individuals' acceptance and self-esteem. Various factors, including tooth shape, position, and gum tissue levels, contribute to smile aesthetics. As the universal expression of human emotion, a smile transcends cultural, linguistic, and socioeconomic barriers, conveying positive emotions like love, joy, and acceptance. Orthodontic treatment, aimed at enhancing dental alignment, must respect biological boundaries to ensure optimal outcomes without compromising periodontal health. This article reviews periodontal interventions necessary before, during,.....

Keywords: Interrelationship, Interdisciplinary, Plaque accumulation, Orthodontic treatment, Periodontal treatment, Clinical assessment

[1]. Pasquinelli LK. Periodontal plastic surgery as an adjunctive therapeutic modality for esthetic restorative dentistry. J Calif Dent Assoc. 2005; 33(3):217-221.
[2]. Butler B, Kinzer GA. Managing esthetic implant complications. Compend Contin Educ Dent. 2012; 33(7):514-188, 520-522.
[3]. Harris RJ. Treatment of a previously placed autogenous masticatory mucosa graft (free gingival graft). A case report. J Periodontol. 1998; 69(6):717-723.
[4]. Polack MA, Mahn DH. Biotype change for the esthetic rehabilitation of the smile. J Esthet Restor Dent. 2013; 25(3):177-186.
[5]. Ravon NA, Handelsman M, Levine D. Multidisciplinary care: periodontal aspects to treatment planning the anterior esthetic zone. J Calif Dent Assoc. 2008; 36(8):575-584.