iosr-JDMS   Volume-15 ~ Issue-4 ~ April-2016

Abstract: The Siddha system of medicine exhibits its glory and significance since time immemorial. It is essentially concerned about utilizing the flora and fauna of the universe for the benefit of the society. Present day treatment modalities for hepatic disorders involve ready use of herbal drugs. Santha santhrodhaya mathirai(SSM) is the widely used Siddha herbo medicinal formulation for the treatment of Pitha suram (Disorders of Liver associated with or without fever) .............

Keywords: Siddha, Santhasanthrodhayamathirai , Herbomineral, acute oral toxicity, Hepatic disorder .

[1]. B. M. Gupta, Adarsh Bala,Mueen Ahmed K.K,Ritu Gupta. Liver disorders: A scientometric study of publication outputs from India during2003-2012.International Journal of Medicine and Public Health Vol4(1), 2014.
[2]. T.S K. Mohamed Saleem, C. Madhusudhana Chetty, S. Ramkanth, V.S.T. Rajan, K. Mahesh Kumar, Gauthaman Hepatoprotective Herbs – A Review Int. J. Res. Pharm. Sci. 2010
[3]. Vol-1(1); 1-5
[4]. Sage Yugi, Yugi vaithiya Sinthamani , Indian medicine and Homeopathy department. Chennai 106 , 2nd edition 2005, .43
[5]. Thiyagarajan. R., Gunapadam Thathu Jeeva vakuppu part -2& 3, Indian medicine and Homeopathy department. Chennai 106 , 4th edition 2004 , 282-440.

Abstract: Spinal anaesthesia is the most preferred regional anaesthesia technique as it is easy to perform, economical and produces rapid onset of anaesthesia and complete muscle relaxation. . Fentanyl, a lipophilic opioid agonist , is used as an adjuvant, which prolongs the duration of spinal block .Dexmedetomidine, an α–2 agonist drug, when given intrathecally, significantly prolongs the duration of spinal block. Therefore, the present study was performed to compare Fentanyl and Dexmedetomidine in their efficacy as adjuvants to sub arachnoid block......

Keywords: Intrathecal Bupivacaine,dexmedetomidine,fentanyl

[1]. Nicholas M. Greene "Distribution of local anesthetic solution within the subarachnoid space", AnesthAnalg 1985 (64): 715 - 730.
[2]. B.R. Raymond Fink "Mechanisms of differential axial blockade in epidural and subarachnoid anaesthesia", Anesthesiology, 1989 (70): 815-858.
[3]. AH Dickenson "Spinal cord pharmacology of pain", Br. J Anesth 1995 (75):193- 200.
[4]. Michael J Cousins and Laurence E Mather "Intrathecal and epidural administration of Opioids", Anesthesiology, 1984 (61) : 276-310.
[5]. Wolfgang C. Ummenhofer, Rosalin H. Arends, Danny SD "Comparative spinal distribution and Clearance Kinetics of Intrathecally administered Morphine, Fentanyl, AlFentanyl and Sufentanil", Anesthesiology 2000 (92) : 739-753.

Abstract: Today, mental disorders are attached with negative and stigmatising attitudes, which are often due to lack ofknowledge about mental illness. It has been hypothesized that as the exposure to psychiatry increases, attitude toward psychiatry increases. Objective-Present study was designed to know the attitude of intern students towards psychiatry before and after their psychiatry posting using 30 item Attitude towards Psychiatry questionnaire.............

Keywords: Stigma, attitude, mental disorders, Psychiatry, medical students

[1]. PW. Corrigan, A. Green, R. Lundin, MA. Kubiak and DL. Penn, Familiarity with and social distance from people who have serious mental illness,PsychiatrServ, 52,2001,953-8.
[2]. AF. Furnham, Medical students‟beliefs about nine different specialties, Br Med J (clin Res Ed), 293(6562), 1986, 1607-10.
[3]. DD. Hunt, et al., Frequent and effect of negative comments ("badmouthing") on medical students "career choices,Acad Med, 71(6),1996,665-9.
[4]. S. Rajagopal, K. Singh, and E. Godfrey, Psychiatry as a career choice compared with other specialties: a survey of medical students, Psychiatry Bulletin, 28, 2004, 444-446.
[5]. P. Tharyan, T. John, A. Tharyan, and D. Braganza, Attitude of "tomorrow‟s doctors‟ toward psychiatry and mental illness, Natl Med J India, 14(6), 2001, 355–9.

Abstract: Concept of fast tracking in anesthesia is getting popular nowadays. α 2 agonists are first approved by FDA for only sedation in ICU. But at present they are explored in various surgeries and in various routes. Intoduction: In present study we evaluate efficacy of Clonidine and Dexmedetomidine in neuroanaesthesia for various intracranial tumors and pituitary adenomas............

Keywords: Dexmedetomidine; Clonidine; Neuroanaesthesia; Fastracking.

[1]. Kuraishi Y, Hirota N, Sato Y, Kaneko S, Satoh M, Takagi H. Noradrenergic inhibition of the release of sobstance P from the primary afferents in the rabbit spinal dorsal horn. Brain Res 1985;359:177-182
[2]. Virtanen R, Savola JM, sanoo V, Nyman L. characterization of selectivity, specificity and potency of medetomidine as an a2 adrenoreceptor agonist. Eur J Pharmacol 1988;150:9-14
[3]. Kallio a, scheinin M, Koulu m, Ponkilainen R, Ruskoaho H, Viinamaki O, scheinin H. effects of dexmedetomidine , a selective α2 adrenoreceptor agonist, on hemodynamic control mechanism. Clin Pharmacol Ther 1989;46:33-42
[4]. Bekker A,Sturaitis MK: dexmedetomidine in neurosurgery.open Neurosurgery journal;volume57;july 2005.
[5]. McCormick JM, McCormick PW, Zabramski JM, Spetzler RF,: intracranial pressure reduction by a central α2 adrenoreceptor agonist after subarachnoid haemorrhage. neurosurgery 32:974-979,1993

Abstract: Hemorrhoids are highly vascularized cushions forming discrete masses of thick submucosa, containing blood vessels, elastic and connective tissue within the normal anal canal. Hemorrhoidectomy is established surgical procedure for third and fourth degree haemorrhoids. There are two methods of hemorrhoidectomy - Milligan-Morgan technique which is more common and also called as open hemorrhoidectomy in which the wound is left open and healing occurs by secondary intention and closed/ Ferguson procedure in which the wound is closed with absorbale sutures......

Keywords: Ferguson, Hemorrhoidectomy, Milligan-Morgan

[1]. Gordon PH, Nivatvongs S. Principles and practice of surgery for colon, rectum and anus. 1st ed. Quality Medical Publishing Inc;
1992. p. 1:10–38, 2:51–62; 8:180–97.
[2]. Keighley and Williams. Surgery of anus, rectum and colon. 3rd ed. Vol 1. Philadelphia: Saunders Publications;. 2008. p. 351–422.
[3]. Russell RCG, Williams NS, Bulstrode CJK. Anus and anal canal. Bailey and Love's short practice of surgery. 24th ed. Arnold
Publications; 2004. p. 1242–63.
[4]. Kubhchandani I, Paonessa N, Azimuddin K. Surgical treatment of haemorrhoids. 2nd ed. Springer; 2009. p. 1–5.

Abstract: Method: Prospective study of 150 patients with suspected osteoporosis and underwent dexa scan. The inclusion criteria are patients above 50 years of age and trivial injury. The exclusion criteria are any pathological fracture, age above 50 years, any associated fractures. All 150 patients were assessed by various risk factors like age, gender, weight ,alcohol etc.............

Keywords: OSTEOPOROSIS, DEXA, BMD

[1]. AC Courtney, EF Wachtel, ER Myers and WC Hayes Age-related reductions in the strength of the femur tested in a fall-loading configuration J Bone Joint Surg Am. 1995; 77:387-395.
[2]. David Metcalfe "‟The pathophysiology of osteoporotic hip fracture‟‟ MJM 2008; 51-57.
[3]. Irene Lambrinoudaki and Annie W.C. Kung,‟‟ Management steroid- induced osteoporosis‟‟ Chinese medical journal 2000; 113 8 681-685.
[4]. J. Porthouse, Y.F. Birks, D.J. Torgerson, S. Cockayne, S. Puffer and I. Watt "Risk factors for fracture in a UK population: a prospective cohort study" Q J Med 2004; 97:569–574.
[5]. M.K. Karlsson, O. Johnell, B.E. Nilsson, I. Sernbo and K.J. Obrant Bone mineral mass in hip fracture patients Volume 14, Issue 2, March-April 1993, Pages 161-165

Abstract: Sturge-Weber syndrome is an embryonal developmental anomaly resulting from errors in mesodermal and ectodermal development. It is caused by a somatic activating mutation occurring in the Guanine nucleotide-binding protein G (q) subunit alpha gene and characterized by vascular malformations present in the skin (port wine stain), eye, and meninges (leptomeningeal angioma).Neuroimaging can provide sufficient information that can guide radiological diagnosis of related brain abnormalities or to differentiate it from other similar types of brain abnormalities.............

Keywords: Sturge–Weber syndrome;Neurocutaneous disorder; Port wine stain; Computed tomography; Magnetic resonance imaging.

[1]. Bebin EM, Gomez MR. Prognosis in Sturge-Weber disease: comparison of unihemispheric and bihemispheric involvement. J Child Neurol.1988; 3:181–184.

[2]. Thomas-Sohl KA, Vaslow DF, Maria BL. Sturge-Weber syndrome: a review. Pediatr Neurol.2004; 30:303–310.

[3]. Roach ES. Neurocutaneous syndromes. Pediatr Clin North Am.1992; 39:591–620.

[4]. Dilber C, Tasdemir HA, Dagdemir A. et al. Sturge-Weber syndrome involved frontoparietal region without facial nevus. Pediatr Neurol.2002; 26:387–390.
[5]. Marti-Bonmati L, Menor F, Mulas F. The Sturge-Weber syndrome: correlation between the clinical status and radiological CT and MRI findings. Childs Nerv Syst.1993; 9:107–109.

Abstract: Objective: Assessment of pain and analgesic efficacy can be made after extraction of a mandibular third molar. The objective of this study is to determine the effect of preemptive administration of nimesulide, metamizole sodium and placebo on the intensity of postoperative pain after extraction of impacted mandibular third molars.......

Keywords: Preemptive analgesia, Third molar surgery, postoperative pain, VAS

[1]. Kehlet H, Holte K . Effect of postoperative analgesia on surgical outcome. Br J Anaesth 2001; 87:62-72
[2]. Macintyre PE, Ready LB. Acute Pain Management – A Practical Guide, 2nd edn. London: WB Saunders, 2001.
[3]. Isiordia-Espinoza, Sánchez-Prieto, Tobías-Azúa et al. Pre-emptive analgesia with the combination of tramadol plus meloxicam for
third molar surgery: a pilot study British Journal of Oral and Maxillofacial Surgery 2012 ;50: 673–677
[4]. Kaczmarzyk T, Wichlinski J, Stypulkowska J, Zaleska M, Woron J. Preemptive effect of ketoprofen on postoperative pain
following third molar surgery. A prospective, randomized, double-blinded clinical trial. Int. J. Oral Maxillofac. Surg. 2010; 39:
647–652.
[5]. Liporaci JLJ Junior. Assessment of Preemptive Analgesia Efficacy in Surgical Extraction of Third Molars Rev Bras Anestesiol
2012; 62: 4: 502-510

Abstract: Candida species inhabit the gut as normal flora and can assume a pathogenic role when host defenses falter. Aims: To determine the percentage isolation of Candida in diarrhoeal stools, to speciate them and to identify the presence of predisposing factors leading to their proliferation in the gut.........

Keywords: Candida, Diarrhoea, antibiotic usage.

[1] Cohen R, Roth FJ, Delgado E. Fungal flora of the human small and large intestine. N Engl J Med 1969; 280:638.
[2] Gracy M, Suharjone M, Sunoto M, Stone D. Microbial contamination of the gut: another feature of malnutrition. Am J Clin Nutr
1973; 26:1170-4.
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diarrhoea in infants. Mycopathologia 1996; 135:145-7.
[4] Larone DH. Medically important fungi: A guide to Identification. 2nd Ed. Washington DC: American Society for Microbiology,
(New York, Elsevier Publishers, 1987).
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Scand 1974; 63:418-22.

Abstract: Abdominal compartment syndrome and Intra-Abdominal Hypertension have been prevalently identified among patients with surgical emergencies such as pancreatitis and intestinal obstruction and among patients in intensive care unit. Objective: To asses the relationship between pre-operative intra- abdominal pressure and postoperative patient morbidity (with special reference to kidney function and pulmonary atelectasis) and mortality........

Keywords: Abdominal Compartment Syndrome, Intra-abdominal hypertension Intra-abdominal pressure.

[1]. Malbrain ML, Cheatham ML, Kirkpatrick A, Sugrue M, Parr M, De Waele J, et al. Results from the International Conference of Experts on Intra-abdominal Hypertension and Abdominal Compartment Syndrome. I. Definitions. Intensive Care Med. 2006;32:1722–32. [PubMed]
[2]. Emerson H. Intra-abdominal pressures. Arch Intern Med. 1911;7:754–84.
[3]. Baggot MG. Abdominal blowout. Curr Res AnesthAnalg. 1951;30:295–9. [PubMed]
[4]. Fietsam R, Jr, Villalba M, Glover JL, Clark K. Intra-abdominal compartment syndrome as a complication of ruptured abdominal aortic aneurysm repair. Am Surg. 1989;55:396–402. [PubMed]
[5]. Moore EE, Burch JM, Franciose RJ, Offner PJ, Biffl WL. Staged physiologic restoration and damage control surgery. World J Surg. 1998;22:1184–90. [PubMed]

Abstract: Fungal infections of skin and its appendages are more prevalent in India due to hot, humid climate. Other factors which influence the prevalence and severity are malnutrition, poor hygiene, poverty and immune suppressive conditions like diabetes, HIV and cancer chemotherapy etc.Among 100 cases of dermatomycoses 70 Percent were Dermatophytosis, 26 percent cases were pityriasis versicolor and 4 percent of cases were candidiasis. Commonest age groups affected were 21 to 30 years. Males are commonly affected than females. Tinea Corporis is the commonest type followed by pityriasis versicolor Tinea cruris and Onychonycosis.

Keywords: Cutaneous mycoses - Clinical patterns – mycology

[1]. Tony Burns, Stephen Breathnach, Christopher Griffiths and Neil Cox, Rook's Text book of dermatology, eighth edition, Wiley Blackwell 2010.
[2]. JagdishChander, Text Book of Medical Microbiology, 2nd edition, Mehta publishers 2002.
[3]. Petmy LJ, Lando AJ, Kaptue L, Tchinda V, Folefack M. Superficial mycoses and HIV infection in Younde, J. EurAcadDermatolVenereol 2004; 8:301-4.
[4]. A.H.M. El.Said. Studies on Fungi Isolated from Dermatomycoses Patients in Egypt. Mycobiology 30(3): 154-159 (2002).
[5]. Krishnenu Das, SukumarBasak, and Subha Ray. A Study on Superficial Fungal Infection from West Bengal: A Brief Report, J. Life Sci, 1(1):51-55 (2009).

Abstract: Lower gastrointestinal bleeding (LGIB) is a frequent cause of hospital admissions and is a factor in hospital mortality and morbidity. Lower gastrointestinal bleeding is a distinct entity and differs from upper gastrointestinal bleeding in epidemiology, management and prognosis. LGIB accounts for approximately 20 to 33% of all episodes of gastrointestinal haemorrhage. Though it is statistically less common than Upper gastro intestinal bleeding, it has been suggested that LGIB is underreported because most of the patients do not seek medical attention (1).

[1]. Talley NJ, Jones M. Self –reported rectal bleeding in a United States Community: Prevalence- risk factor and health care seeking.
Am J Gastro enterol Nov 1998; 93(11): 2179-81.
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56.
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and primarily managed non-operatively. Dis Colon Rectum Sep 1995; 38(9): 479-82.
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1998; 93 920: 175=78.
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May 2011; 125(5); 456-58.

Abstract: Introduction: Simultaneous traumatic bilateral olecranon fractures are rare as similar forces should act bilaterally to cause the fracture. Very few such cases have been reported. Case report: We present the case of a 28 year old female who presented with pain and swelling of both elbows after a fall. Plain radiograph revealed isolated displaced fractures of both the olecranons. The patient was treated with tension band wiring of both elbows which resulted in complete recovery.....

[1]. Wiegand L, BernsteinJ, Ahn J. Fractures in brief: Olecranon fractures. Clin Orthop Relat Res 2012; 470:3637-3641. [2]. Rouleau DM, Sandman E, van Riet R. Galatz LM. Management of fractures of the proximal ulna. J Am Acad Orthop Surg 2013; 21:149-60.
[3]. Kirmani S, Draviaraj K, Madegowda B, Shahane S. Spontaneous bilateral olecranon fractures in a rheumatoid patient. Ann R Coll Surg Engl 2008; 90: 1-3.
[4]. O'Daly BJ, Harty JA, O'Malley N, KilleenR, McDonnell TJ, Quinlan WR. Bilateral olecranon fracture as first presentation of sarcoidosis: Case report and review of the literature. J Shoulder Elbow Surg 2008; 17: 1-5.
[5]. Citlak A, Güzelb N, Kerimoğluc V , Aynacıc O. Bilateral isolated olecranon fractures after trauma: Report of two cases. J Exp Clin Med, 2014; 31:107-110

Abstract: Context: Cholecystectomy is the most commonly performed operation by general surgeons worldwide and the lesser invasive technique i.e. the laparoscopic cholecystectomy is the preferred operative technique both for the patient as well as for the surgeon. Conventionally laparoscopic cholecystectomy is performed by using three or four ports of various sizes. As cosmesis is an important aspect of laparoscopic cholecystectomy, the trend is now towards use of lesser ports thereby resulting in better cosmesis for patients......

Key words: Laparoscopic cholecystectomy; two ports; simplified technique.

[1]. Sakorafas GH, Milingos D, Peros G. Asymptomatic cholelithiasis: is cholecystectomy really needed? A critical reappraisal 15 years
after the introduction of laparoscopic cholecystectomy. Dig Dis Sci2007; 52: 1313-1325
[2]. Freitas ML, Bell RL, Duffy AJ. Choledocholithiasis: evolving standards for diagnosis and management. World J Gastroenterol
2006; 12: 3162-3167
[3]. Martin DJ, Vernon DR, Toouli J. Surgical versus endoscopic treatment of bile duct stones. Cochrane Database Syst Rev 2006;
CD003327
[4]. Slanetz PJ, Boland GW, Mueller PR. Imaging and interventional radiology in laparoscopic injuries to the gallbladder and biliary
system. Radiology 1996; 201: 595-603
[5]. Portincasa P, Moschetta A, Petruzzelli M, Palasciano G, Di Ciaula A, Pezzolla A. Gallstone disease: Symptoms and diagnosis of
gallbladder stones. Best Pract Res Clin Gastroenterol 2006; 20: 1017-1029

Abstract: Background and Objective: Grip and pinch strength measurements provide an objective index of the functional integrity of the upper extremity. Hand strength evaluation is importance in determining the effectiveness of different treatment strategies or effects of different procedures. As studies on the effect of elbow and wrist positions on grip strength remain controversial, the present study aimed to find out the effect of elbow and wrist joint positions on grip strength and the favorable and advantageous position to improve grasp function.....

Keywords: Grip strength, Hand Dynamometer, Elbow and wrist positions.

[1]. Yong-Ku Kong, Young-Woong Song, et al.Effects of hand position on maximum grip strength and discomfort.HFESA 47th Annual Conference 2011.Ergonomics Australia - Special Edition.
[2]. NurgulArinciIncel, EsmaCeceli, et al.Grip Strength: Effect of Hand Dominance.Singapore Med J2002Vol 43(5): 234-237.
[3]. Parvatikar, V.B. and Mukkannavar, P.B. Comparative Study of Grip Strength in Different Positions of Shoulder and Elbow with Wrist in Neutral and Extension Positions.Journal of Exercise Science and Physiotherapy, Vol. 5, No. 2: 67-75, 2009.
[4]. Pauline W. K. Fong, Gabriel Y. F. Ng. Effect of Wrist Positioning on the Repeatability and Strength of Power Grip. The American Journal of Occupational Therapy, Volume 55, Number 2 March/April 2001.
[5]. Su CY, Lin JH, Chien TH, Cheng KF, Sung YT. 1994 : Grip Strength in Different Positions of Shoulder and Elbow. Arch PhysMed Rehabil. Jul;75(7):812-815.

Abstract: Clinicians have been challenged in the past few years by an increasing variety of mesh related infections following widespread use of meshes after repair of hernias. The possibility of mesh related infection occurring weeks or even years after hernia repairs, should be considered in any patient with chronic, persistent, recurrent sinuses formation following hernia repair.......

Keywords : Hernia repair, mesh related infection, infected mesh removal.

[1]. Falagas ME, Kasiakou SK. Mesh-related infections after hernia repair surgery. Clin Microbiol Infect (2005) 11:3–8
[2]. Taylor, SG, O'Dwyer, PJ. Chronic groin sepsis following tension-free inguinal hernioplasty. Br J Surg. 1999;86:562–565
[3]. Ismail W, Agrawal A, Zia MI. Fate of chronically infected onlay mesh in groin wound. Hernia. 2002;6:79–81
[4]. Tolino MJ, Tripoloni DE, Ratto R, Garcia MI. Infections associated with prosthetic repairs of abdominal wall hernias: pathology, management and results. Hernia (2009) 13:631–7.
[5]. Montgomery A, Fredrich K and Ferlinard K ; Evidence for replacement of an infected synthetic by a biological mesh in abdominal wall hernia repair. FrontSurg. 08 Jan 2016/ http://dx.doi.org/10.3389/fsurg.2015,00067.

Abstract: Background: The aim of thestudy was to produce acceptable pain relief in the parturient without producing motor block using either ropivacaine or bupivacaine in combination with fentanyl (2μg/ml)using PCEA, and to evaluate the differences between the two local anaesthetics, if any. Methods:The study model was a prospective, randomized double-blind study;100 (50 in each group) ASA physical status I and II parturient in the age group 18-30 yrs,.......

Keywords: anaesthesia, obstetric; anaesthetic technique, epidural; anaesthetic local, bupivacaine; anaesthetic local, ropivacaine; analgesic opioid, fentanyl

[1]. Philipsen T, Jensen NH. Epidural block or parenteral pethidine as analgesic in labour; a randomized study concerning progress in labour and instrumental deliveries.Eur J ObstetGynecolReprodBiol 1989;30(1):27-33.
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[3]. Abboud TK, Khoo SS, Miller F, Doan T, Henriksen EH. Maternal, fetal, and neonatal responses after epidural anaesthesia with bupivacaine, 2-chloroprocaine, or lidocaine. AnesthAnalg 1982;61(8):638-44.
[4]. Eddleston JM, Maresh M, Horsman EL, Young H, Lacey P, Anderton J. Comparison of the maternal and fetal effects associated with intermittent or continuous infusion of extradural analgesia. Br J Anaesth 1992;69(2):154-8.
[5]. Santos AC, Arthur GR, Pedersen H, Morishima HO, Finster M, Covino BG. Systemic toxicity of ropivacaine during ovine pregnancy. Anesthesiology 1991;75(1):137-41.

Abstract: Background: The aim of the study is to compare I-gel and Air-Q supraglottic airways in terms of time required for insertion ,ease of device insertion ,no.of attempts taken and incidence of complications. Methods: This randomised observational study was conducted on 60 patients, age of 20-60 years ,elective surgery requiring general anesthesia .patients were randomly allocated in two groups.Group 1 :I – gel(no=30):Group II: Air-Q(no=30).....

Keywords: I-gel, Air-Q, Supraglottic airway MANUSCRIPT;

[1]. Sinha PK ,Misra S .Supraglottic airway devices other than laryngeal mask airway and its protypes; Indian J.Anaesth.2005;49(4);281-292.
[2]. Ramesh S,Jayanthi R.Supraglottic airway devices in children;Indian J Anaesth.2011;55(5);476-482.
[3]. Jindal P, Rizvi A,Sharma JP .Is I-gel a new revolution among supraglottic airway device. M.E.J Anesth 2009;20;53-58.
[4]. Halwagi AE, Massicotte N ,Lallo A ,Gauthier A ,Boudreault, Monique Ruel et al.Tracheal intubation Through the I-gel supraglottic
Airway versus the LMA Fastrach. A Randomised Controlled Trial .Anesth Analg 2012;1;152-6.
[5]. Geetha Bhandari,Subhro.shahi,K.S. A comparative study evaluating I-gel and Air-Q LMA for ventilation in anesthetised and
paralysed patients. Ann. of intl. Med & Den. Res.2015;1(1);25-8.

Abstract: The purpose of this study to evaluate the radiological and pathological response to neo-adjuvant radiotherapy in soft tissue sarcoma.Total 30 patients of soft tissue sarcoma of extremities were treated with neo-adjuvant radiotherapy followed by definitive surgery. All patients had MRI imaging pre and post radiotherapy. Radiological tumor response was assessed by volume changes on axial T1 gadolinium enhanced MRI........

Keywords: Liposarcoma, Neoadjuvant Radiotherapy, Pathological Response, Soft tissue Sarcoma, Volumetric Response.

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Abstract: Background: Chronic fluoride toxicity mainly causes dental and skeletal fluorosis. Aims and Objectives: The study describes the spectrum of clinical and radiological features in 204 patients suffering from endemic fluorosis, residing inNasipur village of Birbhum district of West Bengal. Results and Analysis: The patients mainly belonged to the middle age group ( 41-50 years, 38.24% ), and were mostly males .......

Keyword:Fluorosis, low back pain, stiffness of spine, osteosclerosis.

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Abstract: Myositis ossificans also known as "fibrodysplasia ossificans progressiva" is a severe disabling connective tissue disorder uncommonly seen. Hetrotopic ossifications appear spontaneously or flare up on trauma. These patients present for deformity correction and other surgeries. We report a case of 27 year old female, known case of myositis ossificans posted for hip deformity correction under regional blockade.

Keywords : Myosistis Ossificans, Neuraxial Blockade.

[1] Smith R.49th ENMC-Sponsored International Workshop Report: Fibrodysplasia (Myositis) Ossificans Progressiva (FOP) 14–16 February 1997, Naarden, The Netherlands. Neuromuscul Disord 1997;7:407-10
[2] Shore EM, Feldman GJ, Xu M, Kaplan FS. The genetics of fibrodysplasia ossificans progressiva. Clin Rev Bone Miner Metab. 2005;3:201–204. doi: 10.1385/BMM:3:3-4:201
[3] Kaplan FS, Shore EM, Glaser DL, Emerson S. The International Clinical Consortium on Fibrodysplasia Ossificans Progressiva. The medical management of fibrodysplasia ossificans progressiva: current treatment considerations. Clin Proc Intl Clin Consort FOP 2005;1:1-71.
[4] Singh A, Ayyalapu A, Keochekian A. Anesthetic management in Fibrodysplasia Ossificans Progressiva (FOP): a case report. J Clin Anesth 2003;15:211-13