iosr-JDMS   Volume-16 ~ Issue-12 ~ December-2017

Abstract: Objective: To evaluate the performance of a robotic system for CT-guided biopsy in comparison to the conventional manual technique. Materials and methods: Patientsreferred for CT-guided biopsy were randomly assigned to two groups namely, Robot-Assisted Procedure (Group A) and Conventional Procedure (Group B). Procedure duration, dose length product (DLP), accuracyof the needle positioning, diagnostic performance of the biopsy and rate of complications were evaluated to assess the clinical performance of the robotic system as compared to the conventional technique. Results:All biopsies were successfully performed. Procedure duration and radiation dose were significantly reduced in group A as compared to group.......

Keywords: Robot,Biopsy, Cancer.CT-guidance. Interventional radiology

[1]. MacMahon H, Austin JH, Gamsu G, Herold CJ, Jett JR, Naidich DP, Patz EF Jr, Swensen SJ, Fleischner Society (2005) Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society. Radiology 237:395–400
[2]. Naidich DP, Bankier AA, MacMahon H, Schaefer-Prokop CM, Pistols M, Goo JM, Macchiarini P, Crapo JD, Herold CJ, Austin JH, Travis WD (2013) Recommendations for the management of subsolid pulmonary nodules detected at CT: a statement from the Fleischner Society. Radiology 266:304–317
[3]. Gould MK, Donington J, Lynch WR, Mazzone PJ, Midthun DE, Naidich DP, Wiener RS (2013) Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 143: e93S–e120S
[4]. Tuna T, Ozkaya S, Dirican A, Findik S, Atici AG, Erkan L (2013) Diagnostic efficacy of computed tomography-guided transthoracic needle aspiration and biopsy in patients with pulmonary disease. Onco Targets Ther 6:1553–1557
[5]. Lal H, Neyaz Z, Nath A, Borah S (2012) CT-guided percutaneous biopsy of intrathoracic lesions. Korean J Radiol 13:210–226.

Abstract: Of The Study: To study the effect of byrate exposure on pulmonary function in byrate mine workers.

Keywords: Spirometry, FEV1, FVC, FEV1/FVC, restrictive and obstructive lung diseases

[1]. Koh, D. Work and Health: Textbook of Occupational Medicine Practice. Koh, H; Seng, C. K; Jeyaratnam, J. (eds). (2nd ed). Singapore:
[2]. World Scientific. Koningsveld, E. A. P; van der Molen, H, 2001. |
[3]. Hermanus, MA. Occupational health and safety in mining-status, new
[4]. developments, and concerns. The Southern African institute OF Mining and Metallurgy Journal 2007, (107) : 531-538.
[5]. ATS/ERS Task Force: Standardisation of spirometry. Eur Respir J 2005; 26(2): 319-338

Abstract: Acute pancreatitis is an acute inflammatory process involving pancreas and peri-pancreatic tissue, with a range of severity as well as various local and systemic complications. It is a common disorder causing substantial burden to the health care system. The process involved in acute pancreatitis is complex in which pancreatic damage is caused by pancreatic enzyme activation, which results in an acute inflammatory response. BISAP score is a 5 point bedside score. It is inexpensive to perform and easy to obtain. BISAP uses 5 points: Blood Urea Nitrogen (BUN) > 25mg/dl, impaired mental status evidenced by disorientation or disturbance in mental status, presence of SIRS, age > 60 years and Pleural Effusion . BISAP score has been shown to be accurate in predicting the severity of acute pancreatitis in western population.

Keywords: Pancreatitis, BISAP Score, Pleural effusion.

[1]. Whitcomb DC . Clinical practice. Acute pancreatitis . N Engl J Med 2006 ; 354 : 2142 – 50 .
[2]. Banks PA , Freeman ML. Practice guidelines in acute pancreatitis . Am J Gastroenterol 2006 ; 101 : 2379 – 400 .
[3]. Banks PA. Epidemiology, natural history, and predictors of disease outcome in acute and chronic pancreatitis. Gastrointest Endosc. 2002 Dec;56(6 Suppl):S226-230.
[4]. Gittes GK. Developmental biology of the pancreas: a comprehensive review. Dev Biol.2009 Feb 1;326(1):4–35.
[5]. Taborsky GJ, Mundinger TO. Minireview: The Role of the Autonomic Nervous System in Mediating the Glucagon Response to Hypoglycemia. Endocrinology. 2012 Mar;153(3):1055–62...

Abstract: A prospective study was carried out in 100 burns patients admitted in burns unit of S.V.R.R.Government general hospital,Tirupati over a period of one year from October 2016 to August 2017 to evaluate time related changes in aerobic bacteria colonization and their susceptibility pattern. Introduction: A burn is a wound in which there is coagulative necrosis of the tissue, majority of which are caused by heat. Burn injury is a major public health problem in many areas of the world. Burns predispose to infection by damaging the protective barrier function of the skin, thus facilitating the entry of pathogenic microorganisms and by inducing systemic immunosuppression.(1) Objective: The present study was therefore undertaken to isolate and identify the aerobic bacterial flora in burn patients and its antibiotic susceptibility pattern...........

Keywords: Burn wound infection, Antibiotic susceptibility testing, MRSA.

[1]. Lari AR, Honar HB, Alaghehbandan R: Pseudomonas infections in Tohid Burn Center, Iran. Burns 1998; 24: 637-641.
[2]. Vindenes H and Bjerknes R: Microbial colonisation of large wounds. Burns 1995; 21(8): 575-579.
[3]. Bang RL, Gang RK, Sanyal SC, Mokaddas E, Ebrahim MK. Burn septicaemia: an analysis of 79 patients. Burns 1998 Jun; 24(4): 354–61.
[4]. Bang RL, Gang RK, Sanyal SC, Mokaddas EM, Lari ARA: Beta- haemolytic Streptococcus infection in burns. Burns1999; 25: 242–46.
[5]. Altoparlak U, Erol S, Akcay MN, Celebi F, and Kadanali A. The time-related changes of anti-microbial resistance patterns and predominant bacterial profiles of burn wounds and body flora of burned patients. Burns 2004; 30: 660–64...

Abstract: Introduction: Breast carcinoma is most common malignant tumor and leading cause of carcinoma death in women with more than 1000000 cases occurring worldwide annually[1]. Fine needle aspiration cytology(FNAC) is a convenient and rapid preoperative diagnostic procedure. Materials and Method: Retrospective study done in department of pathology, RIMS, Ranchi from January 2015 to December 2016. It included all patients who presented with breast lump and whose FNAC was performed. Results: Total 626 case presented with breast lump in 2 years out of which 180 cases were carcinoma breast. All age group are included. Breast lump most commonly seen in 21-30years age group comprising of benign lesion. Highest prevalence of Breast carcinoma seen in 41-50 years age group (35.5%). Conclusion: Study was observe mostly in females with rural background. Due.........

Keywords: FNAC, Breast carcinoma

[1]. Parkin DM, Bray F, Ferlay J, Pisani P: Estimating the world cancer burden. Globocan 2000. Int J Cancer 2001; 94:153-156.
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[3]. Kelsey JL, Gammon MD, John EM: Reproductive factors and breast cancer. Epidemiol Rev 1993; 15:36-47. Pathak DR, Osuch JR, He J: Breast carcinoma etiology: current knowledge and new insight into the effects of reproductive and hormonal risk factors in black and white populations. Cancer 2000; 88:1230-1238.
[4]. Wang DY, Rubens RD, Allen DS, Millis RR, Bulbrook RD, Chaudary MA, Hayward JL: Influence of reproductive history of age at diagnosis of breast cancer and prognosis. Int J Cancer 1985; 36:427-432.
[5]. Goss PE, Sierra S: Current perspectives on radiation-induced breast cancer. J Clin Oncol 1998; 16:338-347. Hildreth NG, Shore RE, Hempelmann LH: Risk of breast cancer among women receiving radiation treatment in infancy for thymic enlargement. Lancet 1983; 2:273..

Abstract: This paper presents the implementation of an improved inventory management and control system in a Cath lab store. Inventory management system involves the procurement, stocking, and issue of materials to the maintenance department as and when required. Inventory management is the main area in which many process industries are suffering. The aim of this work is to design inventory models for such a system in a process industry. The existing system of inventory control of items reveals that past data cannot be taken as the major decision criteria. The important decision making criterion related to items is criticality, lead time and consumption value which need to be accounted for effective control of inventory management in the organization. Data are collected from various sources like log books, ledgers, annual financial statements and published articles of the company. ABC Analysis, selective ABC and VED analysis, lead time and service level are incorporated in order to obtain 3D models and suggestions were given to improve the inventory management of items. The key performance indicators were also established to give benchmark operations.

Keywords: Selective inventory control, ABC, VED, MUSIC-3D

[1]. Anonymous, 2008. Supply chain: Cost of goods grab executives' attention. Health Facilities Management, 21, 26-28, 30, 32
[2]. Beier, F.J. 1995. The Management of the supply chain for hospital pharmacies: A focus on inventory manage-ment practices.
Journal of Business Logistics, 16, 153- 177
[3]. Das, J.K. 2001.Inventory control. In: Kaushik, M., Agarwal, A.K., Arora, S.B., Eds., Essentials of Logistics and Equipment
Managemnt, Manual of Post Graduate Diploma in Hospital and Health Management. Indira Gandhi National Open University,
School of Health Sciences, New Delhi.
[4]. Doshi, R.P., Patel, N., Jani, N., Basu, M. and Mathew, Simy 2007.ABC and VED analyses of drug management in a government
tertiary care hospital in Kerala.iHEA 2007 6th World Congress: Explorations in Health Economics Paper.
[5]. Duclos, L.K. 1993. Hospital inventory management for emergency demand. Journal of Supply Chain Management, 29, 29-38.
doi:10.1111/j.1745-493X.1993.tb00016.x.

Abstract: Pro-inflammatory cytokines such as tumor necrosis factor alpha and interlukin -8 played a major role in pathogenesis of oral
ulceration. Recently, considerable attention has been focused on using natural herbs as an effective treatment modality for many types of oral ulcers. Curcumin has potent anti- inflammatory properties. Propolis extract is a bee-metabolized resinous substance that exerts
antioxidant, anti-inflammatory and analgesic effects. Aim of study: The present study was conducted to evaluate and compare the effect of topical application of curcumin and propolis on induced palatal ulcers in rats. Materials and methods: A total of 30 adult male Albino rats were divided into three groups: Group I (control group), Group II (curcumintreated group) and Group III (propolis-treated group)..........

Keywords: IL-8, curcumin, inflammatory mediators, propolis, TNF- α

[1]. Femanio F, Lanz A, Buonaiuto A, et al. Guidelines for diagnosis and management of aphthous stomatitis. Pediatr Infect Dis
J. 2007;26(8):728–732.
[2]. Koh TJ, DiPietro LA. Inflammation and wound healing: The role of the macrophage. Expert reviews in molecular medicine.
2011;13:11-24.
[3]. Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest. 2007;117:514–521.
[4]. Gaspari AA: Innate and adaptive immunity and the pathophysiology of psoriasis. J Am Acad Dermatol 2006; 54: (3): 67-80.
[5]. Patil P, Patil L, Kadam V. TNF-α: A potential therapeutic target for inflammatory bowel disease. Asian Journal of Pharmaceutical
and Clinical Research. 2011; 4(1): 158-166. .

Abstract: Chronic renal failure (CRF) presents with an array of cutaneous manifestations. Cutaneous signs of renal failure are mainly related to chronicity of disease. We evaluated the prevalence of various dermatological manifestations in patients undergoing hemodialysis at least twice a week for minimum of six months at our center. Patients were excluded if they were undergoing hemodialysis less than twice a week or on hemodialysis secondary to ESRD following graft dysfunction. 115 patients were evaluated. Among them, there were 90 male and 25 females. Among the skin changes, pruritus accounted for 53.03%, Xerosis was observed in 49.57%, Diffuse blackish hyper pigmentation was seen in 38.26%. Skin infections was seen in 45.2% of patients. Kyrle's disease was observed only...........

Keywords: Chronic Renal Failure, cutaneous changes

[1]. Tony Burns, Stephen Breathnach, Neil Cox, Christopher Griffths, Rooks Textbook Of Dermatology.(Wiley-Blackwell; Hoboken, NJ 2010)
[2]. Kher V, Madias NE, Harrington JT, et al. End-stage renal disease in developing countries. Kidney International. 2002;62(1):350–362. (PubMed)
[3]. Pastan S, Bailey J. Medical progress: dialysis therapy. The New England Journal of Medicine. 1998;338(20):1428–1437. [PubMed]
[4]. Hajheydari Z, Makhlough A. Cutaneous and mucosal manifestations in patients on maintenance hemodialysis: a study of 101 patients in Sari, Iran. Iranian Journal of Kidney Diseases. 2008;2(2):86–90. [PubMed]
[5]. Nunley JR. Dermatologic manifestations of renal disease. eMedicine. 2002:p. 550. .

Abstract: Intra abdominal hypertension, defined as a sustained increase in Intra abdominal pressure can cause direct mechanical impairment of respiratory, hemodynamic, renal and splanchnic function. Organ dysfunction attributable to increased intra abdominal pressure has been termed the abdominal compartment syndrome. The abdominal compartment syndrome has been increasingly recognized as a source of morbidity and mortality in traumatized patient following laprotomy, typically as a result of massive visceral edema, retroperitoneal hemorrhage, or intra abdominal packing1. Abdominal compartment syndrome has also been reported in non traumatized patients. Various systems are involved in this syndrome first the increased abdominal pressure is transmitted to the pleural space so that lung compliance decreases. Hypoventilation and alteration of ventilation or perfusion distribution lead to hypoxia.........

[1]. Chang MC , Miller PR, D'Agostino RJ, Meredith JW. Effects of abdominal decompression on cardio pulmonary function and visceral perfusion in patients with intra abdominal hypertension. J trauma 1998;44:440-445
[2]. Diebel LN , Dulchavsky SA ,Brown WJ .Splanchnic ischemia and bacterial translocation in the abdominal compartment syndrome. J Trauma 1997;43:852-855
[3]. Nakatani T , Sakamoto Y, Kaneko I, Ando H. Effects of intra abdominal hypertension on hepatic metabolism in a rabbit model.J Trauma 1998;44:446-453
[4]. Saggi BH et al .Abdominal compartment syndrome. J Trauma 1998:45:597-609

[5]. Saggi BH, Bloomfield GL ,Sugarman HJ, et al. Treatment of intracranial hypertension using non surgical abdominal decompression. J Trauma 1999;46:646-651. .

Abstract: Neonatal sepsis was found to be the singleton important cause of high mortality and morbidity of the Sick neonatal care Unit of our institution, where the majority of patients were still striving to find proper measures to access the medical facility in time, being entangled in the webs of poor socio-economic conditions, remoteness and lack of transport facilities, poor hygiene, malnutrition, inadequate antenatal care; and above all, ignorance. In this background, prematurity, low birth weight, birth asphyxia including Hypoxic Ischemic Encephalopathy, even sometimes congenital anomalies, were prominent predisposing factors for neonatal sepsis; often requiring intubation and mechanical ventilation which led to ventilator associated pneumonia (VAP). In this study extended over one year, we intended to search for the predictability of ET tube culture reports for VAP among neonatal sepsis cases, the bacteriological.........

Keywords: ET tube culture, Neonatal sepsis, VAP, Ventilator associated pneumonia

[1]. Liu L, Oza S, Hogan D, Perin J, et al. global, regional and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systemic analysis. Lancet. 2015;385:430-440
[2]. Waters D, Jawad I, Ahmed A, et al. aetiology of community-acquired neonatal sepsis in low and middle economic countries. J Glob Health. 2011;1:154-170
[3]. Seale AC, Blencowe H, Manu AA, et al. Estimates of possible severe bacterial infection in sub-Saharan Africa, South Asia, and Latin America for 2012: A systematic review and meta-analysis. La1ncet Infect Dis. 2014;14: 731-741
[4]. Laxminarayan R, Chaudhury RR.Antibiotic resistance in India: drivers and opportunities for action. PLoS Med.2016;13(3): e1001974
[5]. Charles MP, Easow JM, Joseph NM, Ravishankar M, Kumar S, Umadevi S. Incidence and risk factors of ventilator associated pneumonia in a tertiary care hospital. Australas Med J. 2013;6(4):178-82 .

Abstract: Treatment of distal both bone leg fractures include intramedullary nailing, hybrid external fixation, plate fixation or combining any of thesemodalities. While Interlocking nailing of tibial fractures is advantageous in allowing load sharing without disturbing the extra osseous blood supply and less damage to soft tissues with relatively easy learning curve. For correction of alignment before the insertion of nail and maintaining the alignment and to improve the rotational stability of bone implant complex, fibular plating plays a vital role in the management.Hence in our study we analysed the role of fibular plating in the management of distal both bone fractures of the leg. This..........

Keywords: distal both bone fracture of leg, fibular plating

[1]. Canale S. Campbell's operative orthopaedics. 14 ed. 2017.
[2]. Germann CA, Perron AD, Sweeney TW, Miller MD, Brady WJ.Orthopedic pitfalls in the ED: tibial plafond fractures. Am JEmerg Med 2005;23:357—62.
[3]. McKoy BE, Stanitski CL. Acute tibialtubercle avulsion fractures.Orthop Clin North Am 2003;34:397—403.
[4]. ucholz R, Heckman J, Court-Brown C. Rockwood and Green'sfractures in adults. 6 ed. Philadelphia: Lippincott Williams &Wilkins; 2006.
[5]. Egol KA, Weisz R, Hiebert R, Tejwani NC, Koval KJ, Sanders RW.Does fibular plating improve alignment after intramedullarynailing of distal metaphyseal tibia fractures? J Orthop Trauma .

Abstract: Aim: The present study is evaluate and establish the technique of F.N.A.C as a rapid diagnostic tool for cervical lymphadenopathy in paediatric age group and to study the aspiration cytology smear pattern in cervical lymphadenopathy in children, correlating with histopathological examination where ever necessary. [ where surgical resection was done ]. Material And Methods: This is a hospital based retrospective study conducted over a period of 2 years from January 2015 to December 2016. Total 231 patients attending to O P D of the departments of paediatrics , surgery, medicine, pulmonology and ENT, who were advised F.N.A.C for mass lesions in cervical region are included in the study..............

Keywords: F.N.A.C, Reactive lymphadenitis, Granulomatous Tuberculosis, Lymphoproliferative disorder

[1]. Dr.Minal Panchal, Dr.Y.H.Chavan, Dr.S.A. Deshpande, Dr.S.V.Suvernakar, Role of Fine Needle Aspiration Cytology of Cervical Lymphnode in Paediatric Age Group .IOSR, 2014; vol 13: Issue 3 ver.v, pp 59--63.
[2]. B.Deeva Kumar, P. Anil Kiran. Clinicopathological study of Significant Cerv ical Lymphadenopathy in Children,Ijcmr;vol.4: issue 10 ,pp 2025--2027.
[3]. Mittra P, Bharti R, Pandey MK. Role of Fine Needle aspiration cytology in head and neck lesions of pediatric age group. Journal of clinical and Diagnostic research,2013;7:1055-1058.
[4]. SaasRS, Singh H K, Silverman FJ , Fine needle aspiration cytology, In; Orell SR, Sterett GF,editors.Pediatric Tumors. New Delhi; Churchill Livingstone Ltd.2012.pp445—67.
[5]. Jain M, Majumdar DD, Agarwal K, Basis AS, Choudhury M. FNAC as a diagnostic tool in pediatric head and neck lesions. Indian Pediaaaatr. 1999,36:921—3. .

Abstract: Objective: The aim of this study was to identify the prevalence of anemia and predisposing factors contributing to anemia in pregnant women prior to delivery. Material and Methods: A prospective case-control study was conducted on 1000 women who delivered between 28 and 42 weeks of gestation in the month of September and October 2017 at Government General Hospital, Kakinada. Data on the subjects' socioeconomic and demographic characteristics, pregnancy outcomes and hemoglobin levels within 24 hour prior to delivery were collected. The study population was divided into two groups on the basis of presence of anemia within 24 hours prior to delivery. Anemia defined as hemoglobin level<11g/dL. The prevalence of pre-delivery anemia estimated, and antenatal predictors of anemia were determined using multivariate logistic regression analysis............

Keywords: Demographic Area, Socioeconomic factors, Type of Delivery, Perinatal outcome

[1]. Ezzati M, Lopez AD, Rodgers AA, Murray CR. Comparative quantification of health risks: - global & regional burdern of disease attributable to selected major risk factors, Geneva Switzerland: World Health Organization 2004.
[2]. Ezzati M, Lopes AD, Dogers A, Vander HS, Murray C, selected major risk factors & global & regional burden of disease. Lancet 2002.
[3]. Abou Zahr C, Royston E. maternal mortality. A global facebook Geneva World Health Organization 1991.
[4]. PerezEM, Hendricks MK, Beard JL, et al mother Infant Interactions & Infant development are altered by maternal iron deficiency anaemia, Journal of Nutrition, 2005, 135:850-855.
[5]. Beard JL. Why Iron deficiency is important in Infant development Journal of Nutrition. 2008:138:2534-2536. .

Abstract: Atraumatic extraction is an issue of interest for both dentists and patients, as it preserves the alveolar ridge in a sound state where immediate dental implants are indicated or when rapid healingis needed, or even for successful prosthetic rehabilitation. In this study we are using the new technique of extraction where the extraction is performed atraumatically using the physics forceps , by using a single first class lever, creep,stressdistribution,rather than squeezing and pulling the alveolus. Two patients indicated for extraction of their badly decayed teeth, using atraumatic extraction technique were included in this study as case studies, the time taken for extraction was recorded for each case.Postoperative clinical evaluation was performed on the 3rd and 7th day to check the healing, pain intensity, and presence of any complication . In conclusion:physics forceps may be of a help in certain cases to improve the quality of dental extraction.

[1]. [Nicholas C, Jaime L L, Joseph YK . Extraction Defect: Assessment, Classification and Management. International Journal of Clinical Implant Dentistry,( 2009); 1(1):1-11
[2]. Misch CE, Perez HM. Atraumatic extractions: A Biomechanical Rationale. Dentistry today, (2008); 27(8):100-1.Misch G,Golden R. Less than four minute extraction of any tooth. Dentistry Today. August,(2011); 30(8)
[3]. Huang LTKO, Wino C, Vreeman CR, Hagembe M, Njuguna F, R Matthew, Strother MR, Gramelspacher PG, Assessment Of The Face Validity Of Two Pain Scales In Kenya: A Validation Study Using Cognitive Interviewing. BMC Palliative Care.( 2012); 11: 5.
[4]. Dym H, Weiss A. Exodontia: Tips and techniques for better outcome. Dent Clin N Am. (2012);56:245-66.
[5]. Scull P. Beak and bumper.The Dentist.(2010);6:56-61 .

Abstract: Thickness of the resin cement may vary in teeth restored with fibre reinforced composite post especially in situations with large root canal space. The objective of this study was to evaluate the influence of cement thickness on the bond strength of a fibre reinforced composite post system to the root canal dentine. Methods: Eighteen maxillary central incisors were decoronated. The canals were prepared and the specimens were randomly allocated to 2 groups. (n=9). Group A (low cement thickness) in which canals were enlarged to size 1 drill (1.2mm) and size I posts were cemented (1.2) and Group B were enlarged to Size 3 drill (1.5mm) and size 1 post was cemented (1.2). From each sample, 3 sections were taken (1.5 mm thickness). Cement thickness evaluation was done with Universal...........

Keywords: The increase in cement thickness did not significantly affect the bond strength

[1]. Malferrari S, Monaco C, Scotti R. Clinical evaluation of teeth restored with quartz fiber-reinforced epoxy resin posts. IntJProsthodont2003;16:39-44
[2]. Vallittu PK. A review of fiber-reinforced denture base resins. J Prosthod1996;5:270-276
[3]. Vallittu PK. Experiences of using glass fibres with multiphase acrylic resin systems. Theoretical background and clinical examples. In: vallittupk (ed). The first symposium on fibre reinforced plastics in dentistry. University of Turku, Institute of Dentistry, 1998
[4]. VallittuPK. Strength and interfacial adhesion of frc-tooth system. In: VallittuPK (ed). The second symposium on fibre-reinforced plastics in dentistry. University of Turku, Institute of Dentistry, 2001
[5]. Cormier CJ, Burns DR, Moon P. In vitro comparison of the fracture resistance and failure mode of fiber, ceramic, and conventional post systems at various stages of restoration. J Prosthodont2001;10:26-36 .

Abstract: Background: Oral Lichen Planus (OLP) is "a chronic disorder commonly occurs in elderly people usually women with or without skin involvement". Endothelin-1 (ET-1) is a potent vasoconstrictor implicated in vascular biology and tumor carcinogenesis. The current study investigates the level of salivary ET-1 in OLP patients and a control group. Patients and Methods: saliva samples were collected from 32 OLP patients and 30 apparently healthy subjects. ET-1 levels were measured by ELISA, and the results were evaluated with a Mann-Whitney U Test for statistical analysis.........

Keywords: Endothelin-1; ELISA; Oral Lichen Planus; Saliva

[1]. Gangeshetty N and Kumar BP. Oral lichen planus: Etiology, pathogenesis, diagnosis, and management. World J Stomatol. 2015; 4(1): 12–21.
[2]. Lavanya N, Jayanthi P, Rao UK, and Ranganathan K. Oral lichen planus: An update on pathogenesis and treatment. J Oral Maxillofac Pathol. 2011; 15: 127–32.
[3]. Mahboobi N, Agha-Hosseini F and Lankarani KB. Hepatitis C Virus and Lichen Planus: The Real Association. Hepat Mon. 2010; 10(3) :161–64.
[4]. McCartan BE and Healy CM. The reported prevalence of oral lichen planus: a review and critique. J Oral Pathol Med. 2008; 37(8): 447–53. doi: 10.1111/j.1600-0714.2008.00662.x. Epub 2008 Jul 9.
[5]. Boorghani M, Gholizadeh N, Zenouz AT, et al. Oral lichen planus: Clinical features, etiology, treatment and management; A review of literature. J Dent Res Dent Clin Dent Prospect. 2010; 4: 3–9. .

Abstract: Neonatal period is considered the most important age group at all times as newborn are most vulnerable to disease and death. Sepsis is the commonest cause of neonatal mortality. It is responsible for about 30-50% of total neonatal deaths in developing countries.⁽¹̛ ²⁾ Neonatal sepsis can be classified into two subtypes depending upon whether the onset of symptoms is before 72 hours of life (early onset) or after 72 hours of life (late onset)⁽³⁾.The neonate immune system is underdeveloped. An algorithmic approach utilizes sepsis screen for management of asymptomatic as well as symptomatic neonates with sepsis. Clinical symptomatology can be mild and non-specific. The definite diagnosis based on culture is not available for at least 2 days. Also, none of the tests alone have sufficient accuracy and reliability. So a combination of tests is used to diagnose probable sepsis. This combination is called "Sepsis Screen".⁽⁴⁾Thepresent study was carried out to identify risk factors and clinical profile of neonatal sepsis in the neonatal unit. Aim of the study was to find clinical profile and risk factors associated with neonatal sepsis.

[1]. Bang A T, Band R A, Bactule S B, Reddy H M, Deshmukh. Effect of home based neonatal careand management of sepsis on neonatal mortality; field trial in rural India. Lancet. 1999; 354:p. 1955-61.
[2]. Stoll BJ. The global impact of neonatal infection. ClinPerinatol. 1997; 224:p. 1-21.
[3]. Singh M. care of Newborn. 7thed. New Delhi: Sagar publications; 2010.
[4]. Philip AG, Hewitt JR. Early diagnosis of neonatal sepsis. Pediatrics. 1980; 65: p. 1036-41. [5]. Chandra Madhur Sharma, Ravi PrakashAgrawal, HariomSharan. "Neonatal Sepsis": Bacteria & their Susceptibility Pattern towards Antibiotics in Neonatal Intensive Care Unit. Journal of Clinical and Diagnostic Research. 2013 Nov, Vol-7(11): 2511-2513 .

Abstract: The duration and severity of alcohol withdrawal is a great concern while treating alcohol dependent patients. Hyperbaric oxygen therapy (HBOT) has been used in few centers world over, for faster recovery of withdrawal symptoms. The present study aimed to undertake a preliminary study exploring this possibility. Thirty alcohol dependent patients were recruited in this study. They were divided into A: HBOT group (received hyperbaric oxygen therapy for 90 minutes) and B: non-HBOT group (received normobaric oxygen therapy for 90 minutes) using simple randomization technique. Withdrawal symptoms were assessed daily, using the Clinical Institute Withdrawal Assessment scale (CIWA-Ar). The data collected from the two groups were compared. Statistical analysis used was.........

Keywords: Hyperbaric Oxygenation, Alcohol dependence, Alcohol withdrawal

[1]. World Health Organization (WHO). Global Status report on Alcohol and Health. Geneva, Switzerland; 2014.
[2]. Sassi. Tackling Harmful Alcohol Use: Economics and Public Health Policy. Paris: OECD Publishing; 2015.
[3]. Benjamin J. Saddock, M.D, Virginia A. Saddock, M.D, Pedro Ruiz, M.D. Kaplan & Sadock's Comprehensive Textbook Of Psychiatry. 9th edition. Philadelphia. Lippincott Williams & wilkins; 2009.
[4]. Caetano R, Clark CL, Greenfield TK. Prevalence, trends, and incidence of alcohol withdrawal symptoms: analysis of general

[5]. Sanna E, Mostallino MC, Busonero F, Talani G, Tranquilli S, Mameli M, Spiga S, Follesa P, Biggio G. Changes in GABAA receptor gene expression associated with selective alterations in receptor function and pharmacology after ethanol withdrawal. Journal of Neuroscience. 2003 Dec 17;23(37):11711-24 .

Abstract: Background: Delirium Tremens (DTs) is an emergency situation with high mortality rate ranges from 5-15 % due to respiratory failure and cardiac arrhythmias despite in an era of intensive care and advanced pharmacotherapy. Aims and objectives-,
1. To estimate and co relate the level of serum ions (Na+, k+,Mg2+,Cl-) and hepatic enzymes (ALT, AST, GGT) in alcohol withdrawal patients with and without delirium tremens. Methods: A prospective cross sectional study was conducted for a period of one year from July 2013 to July 2014 at department of psychiatry...........

Keywords: Corelation, hepatic enzymes. serum ions, Mortality of delirium tremens

[1]. Pal H, Kumar A ;Epidemiology of substance abuse, Substance abuse disorder; National drug dependence treatment center,Aiims,newDelhi;2005; 3:8-10
[2]. Delirium tremens; http://emedicine.medscape.com/article/166032l
[3]. Zavagli G, Ricci G, Bader G;The importance of the highest normokalemia in the treatment of early hepatic encephalopathy. Miner Electrolyte Metab 1993;19:362-367
[4]. Lerner WD, Fallon HJ; The alcohol withdrawal syndrome, N Engl J Med 1985; 313:951–2.
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Abstract: Hydatid disease - a common disease in the tropics is caused as a result of infection by tapeworm. The disease is widely spread due to close association with sheeps and dogs. This disease affects different parts of the body with liver and kidney being the commonly affected parts. We present to you a 42-year old man with Hydatid diasease with history of abdominal mass occupying his entire right upper abdominal quadrant with associated pain. Imaging modalities such as Ultrasound and Computed Tomography (CT) scan played a vital role in diagnosing this disease.

Keywords: hydatid, man, ultrasound, computed tomography

[1]. G. Marrone, S.C. Francesca Crino, G. Mamone, V. Carollo, M. Milazzo, S. Gruttadauria, A. Luca and B. Gridelli.Multidisciplinary imaging of liver hydatidosis. World Journal of Gastroenterology: WJG, 18 (13), 2012,1438.

[2]. B.V. Czermak, O. Akhan, R. Hiemetzberger, B. Zelger, W. Vogel et al. Echinococcosis of the liver. Abdom Imaging, 2008, 33: 133-143.

[3]. J. Eckert and P. Deplazes. Biological, epidemiological, and clinical aspects of echinococcosis, a zoonosis of increasing concern. Clinical microbiology reviews, 17(1), 2004,107-135.
[4]. D.S. Shah, H. Parikh, B. Shah, S. Banuprakash, J. Shah. Imaging appearances of hydatid cyst. Ind J Radiol Imag., 2006, 533-535.
[5]. D. Filippou, D. Tselepis, G. Filippou, V. Papadopoulos. Advances in liver echinococcosis: diagnosis and treatment. Cli Gastroentrol Hepatol., 2007: 152-159 .

Abstract: Resistance of metallo-β-lactamase has emerged worldwide among Gram-negative bacilli. There are several non-molecular techniques which take advantage of the enzyme's zinc dependence by using chelating agents, such as EDTA to inhibit its activity. Our laboratory has chosen some simple and cost-effective phenotypic MBL detection methods which will identify such organisms. This study was carried out from 1stJanuary 2015 to 31stDecember 2016 in a tertiary care hospital, Kolkata, West Bengal, India. Urine, throat swabs and wound swabs were collected from patients after admission. GNB were isolated and antibiotic resistance were evaluated by Kirby Bauer'.................

Keywords: Metallo-β-Lactamase(MBL), Gram negative bacilli(GNB), Combined Disc test(CMDT)

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