iosr-JDMS   Volume-17 ~ Issue-6 ~ June-2018

Abstract: Introduction: Hypertensive disorders of pregnancy is a broad spectrum entity complicating pregnancy from 2nd trimester onwards with increasing prevalence leading to unfavourable maternal & foetal outcome Aim: 1. To study the accuracy of elevated S.uric acid levels as a predictor of hypertensive disorders of pregnancy& its complications. 2. To evaluate the maternal & perinatal outcome in relation to raised S. uric acid levels in women with PIH. Methodology: Hundred pregnant women in the age group of 20-40 yrs, in the 3rd trimester of pregnancy, diagnosed as cases of pre ecclampsia, were included in the study after prior informed consent. The patients were investigated & followed up. Records of maternal & foetal outcome and the complications arising due to pre ecclampsia were maintained. The results were correlated with levels of S.uric acid and statistically analysed. Results:The.......

Key words: Pre ecclampsia, Ecclampsia, HELLP syndrome, IUGR, Pre term birth, DIC, APGAR score.

[1]. Steegers EAP, von Dadelszen P, Duvekot JJ, Pijnenborg R. Pre-eclampsia. Lancet 2010;376:631–44.
[2]. von Dadelszen P, Payne B, Li J, Ansermino JM, Pipkin FB, Côté AM, et al. Prediction of adverse maternal outcomes in pre-eclampsia: development and validation of the fullPIERS model. Lancet 2011;377:219–27.
[3]. Payne BA, Hutcheon JA, Ansermino JM, Hall DR, Bhutta ZA, Bhutta SZ, et al. A risk prediction model for the assessment and triage of women with hypertensive disorders of pregnancy in low-resourced settings: the miniPIERS (Pre-eclampsia Integrated Estimate of RiSk) Multi-country Prospective Cohort Study. PLoS Med 2014;11(1):e1001589.
[4]. Kang DH, Finch J, Nakagawa T, Karumanchi SA, Kanellsi J, Granger J, et al. Uric acid, endothelial dysfunction and pre-eclampsia: searching for a pathogenetic link. J Hypertens 2004; 22:229–35.
[5]. Bainbridge SA, Roberts JM. Uric acid as a pathogenic factor in preeclampsia. Placenta 2008;29(Suppl A):S67–72...

Abstract: All major cities of India face haphazard, unplanned expansion leading to increase in population. Ultimately there is creation of slum areas around city peripheries and low-lying areas due to this unchecked growth.. Environmental degradation is fundamentally linked to poverty in India, which is the main obstacle in dealing with environment related problems and health. If effective and practical solutions to remedy environmental hazards are to be taken, this environment poverty nexus cannot be ignored. Objective- To assess environmental risk factors and their resultant diseases in slum areas of Shahabad (Dist. Kurukshetra). Material and methods- This cross sectional........

Key words: Slums, environment, environmental risk factors, diseases.

[1]. WHO/ India statistics. Available from : www.who.int/country/India/en.
[2]. Census of India: Slum population in states/UTs,2011. Available from : www.censusindia.gov.in.
[3]. UN-Habitat. State of the World‟s Cities 2006/2007 (online), Nairobi, Kenya: 2006/7.
[4]. United Nations (UN). The Millennium Development Goals Report. New York, NY: United Nations; 2013.
[5]. Ministry of Urban Housing and Poverty Alleviation. Rajiv Awas Yojana: Guidelines for slum free city planning. New Delhi: Govt. of India; 2010..

Abstract: With the availability of dinoprostone sustained release vaginal pessary in India, for induction of labour (IOL), this study was planned with the aim of studying its clinical efficacy and comparing it with another preparation of dinoprostone which has been available and being used since years for IOL, i.e. instant released intracervical gel. Different study from west has shown the vaginal dinoprostone to be safe and efficacies for IOL, and PGE2 in different forms of tablets, gel and pessary appear to be equally efficacies. The vaginal preparation has an advantage of single application, slow and sustained release of drug over 24 hours, less invasiveness, ease of administration and removal allowing greater dose control. Patients selected for induction were offered sustained release vaginal preparation and intracervical preparation alternatively and relevant data were collected for first 100 patients for each group. There was statistically insignificant difference between the two groups in parity, gestational......

Key words: Induction of Labour, dinoprostone, vaginal pessary, intracervical gel.

[1]. Kandemir O, Dede H, Yalvac S, Aldemir O, Yirci B, et al., "The Effect of Parity on Labor Induction with Prostaglandin E2 Analogue (Dinoprostone): An Evaluation of 2090 Cases", J Preg Child Health April 15, 2015;2:149. [2]. Swartout JP, Ramin KD (2008), "Controlled-release dinoprostonevaginal insert for cervical ripening and labor induction", Expert RevObstetGynecol 3:13-20. [3]. NICE Clinical Guideline number 70, "Induction of Labour" (update of NICE inherited clinical guideline D) National Collaborating Centre for Women's and Children's Health (UK) London: RCOG Press; July, 2008.
[4]. Leduc, D., Biringer, A., Lee, L., and Dy, J. Clinical Practice Obstetrics Committee, Society of Obsetricians and Gynaecologists of Canada. Induction of labour. SOGC Clinical Practice Guideline No. 296, September 2013. J ObstetGynaecol Can. 2013; 36: 248–252.
[5]. DINOPROSTONE 10mg Vaginal Insert in 241 mg hydrogel polymer (cross-linked polyethylene oxide/urethane) with polyester retrieval system. FERRING PHARMACEUTICALS, (Manufactured For: Ferring Pharmaceuticals Inc). Parsippany, Nj 07054 Rev. 02/2016 6870-03..

Abstract: Introduction: Epilepsy is a disorder of the brain. The psychiatric conditions can present either periictally or interictally. Higher rates of psychiatric disorders are observed in people with epilepsy compared with the general population and other medical conditions and that leads to consequences of disability, unemployment, dependence, social limitations, driving restrictions. Aims & Objectives:1.To assess the prevalence and pattern of psychiatric co-morbidity in patient with epilepsy,2.To determine the role of socio-demographic factors in patient with epilepsy having psychiatric illness. Materials & Method: In this cross-sectional study, 200 cases of epilepsy were taken from Medicine OPD, PDU Medial College & Hospital, Rajkot. GHQ-12 scale was applied for screening of psychiatric disorders and thereafter detailed interview was conducted with patient and psychiatric disorders were diagnosed according to DSM-V criteria. Results & Discussion: Psychiatric co-morbidity was...........

Key words: Epilepsy, psychiatric comorbidity.

[1]. Briquet P. Traite´ clinique et therapeutique de l_hysterie. Paris. 1859.
[2]. Morel BA. Traite´ des maladesmentales. Paris: Masson et Cie; 1860. [3]. Gaitatzis A., Trimble, M. R. and Sander, J. W. (2004), The psychiatric comorbidity of epilepsy. Acta NeurologicaScandinavica, 110: 207–220. [4]. Blume W.T, Lunders H.O., Mizrahi E.,Tassinari C., VanEmde B.W. & Engel J.Tr(2001) Glossary of descriptive terminology for ictal semiology: report of the ILAE task force on classification and terminology. Epilepsia42, 1212-18.
[5]. Biraben A., TaussigD.,Thomas P. et al.(2001)Fear as the main feature of epileptic seizures. Journal of Neurology, Neurosurgery and Psychiatry70,186-91..

Abstract: Background: Being the highest contributor to under‑5 mortality, neonatal mortality and morbidity has great impact to the attainment of millennium development goals 4 (MDG 4). In India and other developing countries, this indicator strongly poses a major challenge in achieving this goal. Objectives: To determine the morbidity and mortality pattern of admitted babies in the Sick Newborn Care Unit (SNCU) of Bankura Sammalini Medical College and Hospital,Bankura,West Bengal. Materials and Methods: This is a comparative and descriptive longitudinal study of causes of morbidity and mortality between babies born within (inborn) and outside our hospital facilities (outborn) based on information on place of birth, APGAR scores, age on admission, diagnosis on admission, duration of hospital stay, and outcome of newborns admitted into the sick newborn........

Key words: India, Morbidity, Mortality, SNCU.

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Abstract: Objective: Different tumor and tumor like conditions can affect spinal cord and its supporting structures. They can affect both adults and children. They can lead to severe neurological deficits and several morbidities if not diagnosed in time and treated accordingly. Aim of our study was to assess the distribution, features, localization and extent of tumors of spine at intra-dural region by MRI and to correlate it with the pathology diagnosis. Methods: A total of 116 no of patients diagnosed with tumors of spine by MRI and underwent surgery were provisionally taken for study. Extradural tumors were excluded from study group so that our study included 89 no of patients having intradural tumors. The study was conducted in the departments of Radiodiagnosis, Neurosurgery, and Pathology at SCBMCH, Cuttack, and KIMS, Patia, Bhubaneswar, Odisha, India, from January 2014 to December 2016. It was a retrospective.......

Key Words: Magnetic resonance imaging (MRI), spinal tumors, intradural, extramedullary, intramedullary.

[1]. A. M. Quiles, E. Gomez Rosello, G. Laguillo, R. Garcia, J.-L. Caro, F. Perez, S. Pedraza; A Comprehensive Review of Intraspinal tumors: Diagnostic, classification and radio-pathologic correlation : GIRONA/ES,10.1594/ecr2013/C-2112
[2]. Dr Ravi N et al: MRI Evaluation of Different Spectrum of Spinal Tumors: SSRG International Journal of Medical Science (SSRG-IJMS) – volume 1 Issue 2 December 2014:pp14-30
[3]. Dr Ravi N et al: MRI Evaluation of Different Spectrum of Spinal Tumors: SSRG International Journal of Medical Science (SSRG-IJMS) – volume 1 Issue 2 December 2014:pp14-30
[4]. Constantini S, Houten J, Miller D, et al. Intramedullary spinal cord tumors in children under the age of 3 years. J Neurosurg 1996; 85: 1036–1043.
[5]. Koeller KK, Rosenblum RS, Morrison AL. From the archives of the AFIP: neoplasms of the spinal cord and filum terminale—radiologic-pathologic correlation. RadioGraphics 2000; 20:1721–1749.

Abstract: BACKGROUND:-Induction of labour defines as artificial initiation of uterine contractions leading to progressive dilatation and effacement of cervix and delivery of baby. Includes women with intact membranes and those with spontaneous rupture of membranes but who are not in labour. Induction of labour is indicated when the risk of continuing pregnancy, for the mother or the fetus, exceeds the risk associated with induced labour and delivery. Many different methods have been used, but prostaglandins remain a preferred method for cervical ripening and labour induction. Dinoprostone is the preferred form of prostaglandin and has been shown to increase the rate of vaginal delivery within 24 h and is generally given when the cervix has a Bishop's score of ≤six......

Key Words: Induction, Cerviprime Gel, Propess, Intracervical, Dinoprostone(PGE2 Gel), Bishops Score.

[1]. American College of Obstetricians and Gynecologists. ACOG practice bulletin. Clinical Management Guidelines for Obstetrician-Gynecologists. No. 107. Induction Labor Obstet Gynecol. 2009;114:386-97.
[2]. RANZCOG College statement. Statement No. C-Obs 22, "Use of prostaglandins for cervical ripening prior to the induction of labour," http://www.ranzcog.edu.au/component/content/ article/503-c-obs/423-use-of-prostaglandins-for-cervical-ripening- prior-to-the-induction-of-labour-c-obs-22-.html.
[3]. M.Mukhopadhyay, K. J. H. Lim, and F. M. Fairlie, "Is propess a better method of induction of labour in nulliparous women?" Journal of Obstetrics and Gynaecology, vol. 22, no. 3, pp. 294– 295, 2002.
[4]. E. M. Kho, L. Sadler, and L. McCowan, "Induction of labour: a comparison between controlled-release dinoprostone vaginal pessary (Cervidil) and dinoprostone intravaginal gel (Prostin)," Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 48, no. 5, pp. 473–477, 2008.
[5]. S. A. El-Shawarby and R. J. Connell, "Induction of labour at term with vaginal prostaglandins preparations: a randomised controlled trial of "Cerviprime gel vs Propess," Journal of Obstetrics and Gynaecology, vol. 26, no. 7, pp. 627–630, 2006..

Abstract: Aim and Background: The aim of this study was to detect the carrier rate of methicillin-resistant Staphylococcus aureus (MRSA) among the health care workers (HCWs) in a tertiary care hospital and determine the antimicrobial susceptibility for topically used antimicrobial agents. Increasing number of infections are caused by MRSA strains in the hospitals. About 5% of HCWs become colonized with MRSA and frequently act as vectors of transmission[1]. Methods: Nasal swabs from 200 healthcare workers were collected in the month of October 2017. These swabs were processed using standard laboratory techniques. Results: Of the samples of 200 HCWs we have collected, 52(26%) were nasal carriers of S. aureus and among them 17(32.7%) were carriers of MRSA. The overall carrier rate of MRSA was 8.5 %(17/200). All isolates were sensitive to bacitracin; 76.47.......

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[4]. Wertheim, Heiman FL et al. The role of nasal carriage in Staphylococcus aureus infection The Lancet Infectious Diseases , Volume 5 , Issue 12 , 751 - 762
[5]. Reagan, D. R., B. N. Doebbeling, M. A. Pfaller, C. T. Sheetz, A. K. Houston, R. J. Hollis, and R. P. Wenzel. 1991. Elimination of coincident S. aureus nasal and hand carriage with intranasal application of mupirocin calcium ointment. Ann. Intern. Med. 114:101–106).

Abstract: External inflammatory resorption and replacement resorption (ankylosis) of the root are complicating factors that may result from traumatic dental injures during replantation or repositioning of avulsion and extrusive luxation cases. This is a case of a patient who was followed-up for over 28 years following avulsion of a tooth and extrusive luxation of four teeth and outlines factors that influence the occurrence of resorption..

Keyword: Avulsion teeth, extrusive luxation teeth, root resorption, long-term follow-up.

[1]. Andreasen JO, Andreasen FM. Essential of traumatic injuries to the teeth. Louis. 2nd Edn. Munksgaard, Copenhagen. 2000；85-140.
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Abstract: It has been known for many years that ESRD is associated with very high mortality. The burden of Chronic Kidney Disease is increasing in alarming proportion all over the world. In India, especially in rural areas due to lack of financial resources & infrastructure, quality of dialysis care is not high. This study assesses the facilities and designing required to establish a dialysis centre as per the prevalent guidelines. Objectives: 1. Assessing the physical facilities and area required to setup a 30 bedded dialysis unit
2. Architectural and engineering planning for the dialysis unit.............

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Abstract: MRI evaluation of perianal fistula plays crucial role in diagnosis, classification and surgical management of fistulous disease. Perianal fistulisation is unusual condition but significantly contribute to gastrointestinal morbidity. By use of proper technique, we can accurately diagnose and classify perianal fistula with better depiction of fistulous track and secondary extensions. Our study aims to evaluate efficiency of MRI in detection and classification of perianal fistula. A total of 50 patients who were diagnosed during the study period June 2017 to June 2018 were included andMRI findings were reviewed, tabulated and analysed. MRI fistulography prove to be highly sensitive investigation for perianal fistula with 100% detection rate of fistulous track, its extension and relation to internal and external sphincter. MRI fistulography is highly sensitive and specific in diagnosing type and extent of perianal fistula. All of the fistula were correctly identified and confirmed on surgery.

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Abstract: Cancer is a major public health problem and the third leading cause of death in Malaysia . Breast and ovarian cancers are the first and fourth most common cancer among women in Peninsular Malaysia. Our aim is to assess the risk factors in healthy young adult female students from UMS and will act as an input for further prevention of breast and ovarian cancer. Total 278 Medical and Nursing students from Faculty of Medicine and Health Sciences were participate in this study. Assessing the hereditary risk factor, total 12.34% gives positive result for history of breast tumour in first degree relatives and for ovarian tumour total.......

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[5]. Saxena N, Hartman M, Bhoo-Pathy N, Lim JN, Aw TC, Iau P, et al. Breast cancer in South East Asia: comparison of presentation and outcome between a middle income and a high income country. World J Surg. 2012 Dec; 36(12): 2838-46