iosr-JDMS   Volume-16 ~ Issue-10 ~ October-2017

Abstract: BACKGROUND: Seizure disorder is one of the most common treatable neurological disorders of brain.The essential diagnostic evaluation for unprovoked seizure remains source of debate. Only few studies have evaluated the utility of EEG (Electroencephalogram) and Neuroimaging in seizure disorder in clinical practice. OBJECTIVE: To determine correlation between clinical features, EEG findings and neuroimaging (MRI-Magnetic Resonance Imaging) abnormalities in children with seizure disorder. MATERIAL AND METHODS: It is cross sectional, non-interventional, observational study carried out from March 2014 to May 2015. We enrolled children diagnosed with.........

Keywords –EEG, MRI, Seizure disorder

[1]. Atlas: Epilepsy Care in the World. Programme for Neurological Diseases and Neuroscience,Department of Mental Health and Substance Abuse, World Health Organization; 2005.
[2]. Mikati MA. Seizures in childhood.Kliegman R. Nelson Textbook of Pediatrics; Elsevier/Saunders; 2011; page 2013
[3]. Bano S, Yadav SN, Chaudhary V, Garga UC. Neuroimaging in epilepsy. J PediatrNeurosci 2011 Jan;6(1):19-26.
[4]. Wolf P. Determinants of outcome in childhood epilepsy. ActaNeurolScandSuppl 2005;182:5-8.
[5]. Patel NH, Jain AR, Iyer VK, Shah AG, Jain DA, Shah AA. Clinico – diagnostic and therapeutic relevance of computed tomography scan of brain in children with partial seizures. Ann Indian AcadNeurol 2013 Jul;16(3):352-6.

Abstract: As COPD progresses, patients develop more frequent and severe exacerbations. AECOPDs can range in severity from mild to life threatening. A disease specific severity of illness score for AECOPD would serve to improve treatment. It would identify patients who might potentially benefit for early and aggressive use of selected interventions, such as noninvasive ventilation. In this study, we selected BAP-65 score as a predictive tool for assessing the severity and the need for mechanical ventilation or mortality in AECOPD patients. 80 patients were included in the study and grouped basing on the score. Accordingly 9, 30, 24,12,5 patients were grouped under score groups 0,1,2,3,4 respectively. Analysing the data statistically for the correlation between the total score and end points showed..........

Key words: AECOPD, BAP-65 score, need for mechanical ventilation and mortality.

[1] Lopez AD, Shibuya K, Rao C, et al. Chronic obstructive pulmonary disease: current burden and future projections. European Respiratory Journal 2006;27:397-412.
[2] Reilly J, Silverman E, Shapiro S (2011) Chronic Obstructive Pulmonary Disease. In: Longo DL, Fauci AS, Kasper DL, et al. (eds.) Harrison‟s Principles of Internal Medicine (18th edn.) New York: McGraw-Hill pp: 2151-2160.
[3] Burge S, Wedzicha JA. COPD exacerbations: definitions and classifications. European Respiratory Journal Suppl 2003;41:46s-53s.130.
[4] Celli BR, Barnes PJ. Exacerbations of chronic obstructive pulmonary disease. European Respiratory Journal 2007;29:1224-38.
[5] Hurst JR, Vestbo J, Anzueto A, et al; Evaluation of COPD Longitudinally to Identify Predictive Surrogate End points (ECLIPSE) Investigators. Susceptibility to exacerbation in chronic obstructive pulmonary disease. New England Journal of Medicine. 2010; 363(12):1128-1138.

Abstract: Introduction: Huntington's disease (HD) is a dominantly progressive, inherited neurodegenerative disorder characterized clinically by a combination of abnormal involuntary movements mainly chorea, neuropsychiatric manifestations, and dementia. It is caused by an unstable CAG repeat expansion in the gene IT15 which encodes a Huntingtin protein. The characteristics of Juvenile Huntington's Disease (JHD) differ from those of adult‑onset HD, as chorea does not occur in JHD although bradykinesia, dystonia, and signs of cerebellar disorder such as rigidity are present frequently in association with convulsive episodes and psychotic manifestation........

Keywords: CAG, Huntington Disease-DNA PCR, Juvenile Huntington's disease (JHD),Magnetic Resonance Imaging, tremors

[1] Gonzalez‑Alegre P, Afifi AK. Clinical characteristics of childhood‑onset (Juvenile) Huntington disease: Report of 12 patients and review of the literature. J Child Neurol 2006;21:223‑9.
[2] Ross CA, Margolis RL. Huntington's disease. Clin Neurosci Res 2001; 1:142-152.
[3] The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-983.
[4] Cardoso F, Seppi K, Mair KJ, Wenning GK, Poewe W. Seminar on choreas. Lancet Neurol. 2006 Jul;5(7):589–602.
[5] Quarrell OW, Nance MA, Nopoulos P, Paulsen JS, Smith JA, Squitieri F. Managing Juvenile Huntington's disease. Neurodegener Dis Manag2013;3:267-76.

Abstract: This retrospective study was conducted in a peripheral medical college of west Bengal nearly 180 km away from state capital during September 2015 to August 2017 to assess the pathological cause & manner of death amongst burnt female victims coming for medicolegal autopsy. Total 100 burn cases were taken all togther in all age group of female deceased. It was predominantly 65% cases of early death within 36 hrs of onset because of shock either neurogenic or hypopvolumic & 32% cases were septicaemic shock & remaing 3% of other causes like injuries of vital organs. Among 100 cases 54% are from accidents,44% suicidal ,1% homicidal & 1% undetermined.

Keywords: homicidal, medicolegal autopsy, shock, suicidal

[1] Vaghela PC, Ahir GN, Patel MH. Epidemiology of fatal burn cases in GK General Hospital, Bhuj.National Journal of Community Medicine. 2012;3(2):326-29.
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Abstract: Introduction: Intra operative facial nerve monitoring using nerve mapper during parotid surgeryhas shown to decrease the incidence of post operative facial nerve palsy. Aims and objectives:  To assess the incidence of facial nerve palsy following parotidectomy.  To assess the role of intraoperative facial nervemonitors (mapper) in preventing facial palsy. Materials And Methods Study design Longitudinal study - Prospective. Study period Aug 2015 to Aug2017 Sample size 36........

Keywords: parotid swelling, facial nerve, nerve mapper

[1]. Sabiston text book of surgery; 19th edition; 2012.
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[5]. Witt RL. Facial nerve monitoring in parotid surgery: the standard of care? Otolaryngological Head Neck Surgery 1999; 121(6): 846...

Abstract: Background: Since few decades in the state of Andhra Pradesh the high number of Incisional Hernia is being observed among the young & middle aged female population because of happening of high rate of caesarean sections as the commonest mode of safe delivery being practiced in private health setup, alarmed me to conduct the present study on female Incisional hernia patients attending government general hospital Guntur, Andhra Pradesh, India. Objectives: 1. To know the Socio-demographic profiles of the study group 2. To identify the factors associated with the development of Incisional hernia.............

Keyords: Incisional hernia, LSCS (Lower Segment Caesarean Section), House wives.

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continuous vs interrupted suture technique. Ann Surg 1983; 197:238-43
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randomized trial. Ann Surg 1995; 61:980-3
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Abstract: Hysterectomy is the most commonly performed major gynecological surgery worldwide .The cause for hysterectomy being done varies from country to country and region to region. Hysterectomy may be total /complete, partial /subtotal / supracervical hysterectomy. The study is a retrospective analysis of 454 cases of hysterectomy specimens received in Department of Pathology ,Govt.Stanley Medical College, Chennai, Tamilnadu during a one year period from January to December 2016. The objective of this study is assess the age distribution of females undergoing hysterectomy and analyze the various histopathological features of uterine lesions in these specimens. In our study..............

Keywords-:Hysterectomy, Simple hyperplasia, Endometrioid Cancer, Carcinoma Cervix, Benign, Malignant, Adenomyosis, Leiomyoma

[1]. Forae GD, Aligbe JU. Histopathological patterns of endometrial lesions in patients with abnormal uterine bleeding in a cosmopolitan population. J Basic Clin Reprod Sci 2013;2:101-4.
[2]. Wu JM, Wechter ME, Geller EJ. Hysterectomy rates in the United States 2003. Obstet Gynaecol 2007; 110 (5): 1091-95
[3]. John, A., Rock, M. D., Jhon, D., & Thompson, M. D. (2003). Telind's Operative Gynaecology. 1st edition Lipincott –Ravenplace.
[4]. Yakasai, D. I. (2013). Complications of hysterectomy: A review. British Journal of Science, 9, 23-30.
[5]. Bahamondes, L., Bahamondes, M. V., & Monteiro, I. (2008). Levonorgestrel-releasing intrauterine system: uses and controversies. Expert review of medical devices, 5(4), 437-445.

Abstract:Purpose: To study the effect on intraocular pressure during the bench press exercise in young athletes. Methods: Descriptive study was done. 36 healthy athletes were selected without any preexistent ocular or systemic disorder. IOP immediately before and during the bench press exercise was measured by single examiner. Results: Mean IOP in the right eye recorded before exercise was 13.86.±2.22 mm Hg. The mean IOP measured during the exercise was 21.35±1.85 mm Hg, with p value(<0.001) statistically significant.
Discussion: Significant rise in intraocular pressure from the baseline was observed which was statistically significant.

Keywords: Bench press exercise, Intraocular pressure, Schiotz tonometer

[1]. Risner D, Ehrlich R, Kheradiya NS, et al (2009) Effects of exercise on intraocular pressure and ocular blood flow: a review. J
Glaucoma 18:429–436. doi: 10.1097/IJG.0b013e31818fa5f3.
[2]. Rüfer F, Schiller J, Klettner A, et al (2014) Comparison of the influence of aerobic and resistance exercise of the upper and lower
limb on intraocular pressure. Acta Ophthalmol 92:249–252. doi: 10.1111/aos.12051
[3]. Vera J, Jiménez R, García JA, Cárdenas D (2017) Intraocular pressure is sensitive to cumulative and instantaneous mental
workload. Appl Ergon 60:313–319. doi: http://dx.doi.org/10.1016/j.apergo.2016.12.011
[4]. Aykan U, Erdurmus M, Yilmaz B, Bilge AH (2010) Intraocular pressure and ocular pulse amplitude variations during the Valsalva
maneuver. Graefe's Arch Clin Exp Ophthalmol 248:1183–1186. doi: 10.1007/s00417-010 -1359-60
[5]. Song, H.Y., et al., The Effect of Positional Changes during Heavy Weight Lifting on Intraocular Pressure. J Korean Ophthalmol
Soc, 2009. 50(12): p. 1831-1839.

Abstract: Backgroud : Extra pulmonary tuberculosis (EPTB) is one of the major health problem in india. The term EPTB, which includes all forms of tuberculosis other than pulmonary tuberculosis (PTB), has a broad spectrum of clinical manifestations, hence a real diagnostic challenge.Obtaining material for Histopathological examination&culture is much more difficult for diagnosis. Material and methods : This is an observational study of patients of all types of Extra pulmonary tuberculosis from January 2016 to August 2017 in all age groups, evaluated at RIMS Medical College and Hospital , Ongole ,Andhra Pradesh, India.........

Keywords: Extra pulmonary tuberculosis, Pleural TB, lymph node TB,CNS TB...

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[3]. Zhang X, Andersen AB, Lillebaek T, Kamper-Jørgensen Z, Thomsen et al. Effect of sex, age, and race on the clinical presentation
of tuberculosis: a 15-year population-based study. Am J Trop Med Hyg. 2011 Aug; 85 (2):285-90.
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Abstract: Introduction: Chronic Osteomyelitis has been continuing as the most important cause of morbidity among patients with bone infections. Even though early detection of cases and advanced treatments are in process, osteomyelitis is still continued as a major problem due to treatment failures and multidrug resistance. This study was conducted to determine the pus culture of chronic osteomyelitis and their susceptibility pattern to variousantimicrobial drugs. Aim: 1)To isolate and identify the Aerobic bacteria causing chronic osteomyelitis in one hundred fifty patients attending Orthopaedic outpatient department and those admitted in Orthopaedic wards of Shri M.P. Shah Government Medical College, Jamnagar...........

Keywords: Osteomyelitis, S.aureus,P. aeruginosa, antibiotic resistance

[1]. Canale ST, James HB. Campbell's Operative Orthopaedics, 11thed. St Louis Missouri: Mosby 2008; 1: 695-709.
[2]. Zuluaga AF, Galvis W, Vesga O et al.. Etiologic diagnosis of chronic osteomyelitis. Arch Intern Med 2006; 166: 95- 100.
[3]. Abid AS, Ehan AH, Yonis AR. Epidemiological and bacteriological study of chronic osteomyelitis. Tikrit Medical Journal 2008; 14(1): 59-62.
[4]. Reza M, Shahab F, Jalal K, Farhad J et al.. Epidemic assessment of bacterial agents in osteomyelitis and their antibiotic resistance pattern determination. Journal of Biological Sciences 2008; 8(2): 478-481.
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Abstract: Purpose: To analyze the indications and outcome of use of dry amniotic membrane graft for reconstruction of various conjunctival disorders . Materials And Methods: It is a prospective interventional study done on patients attending a tertiary health care centre with disorders of conjunctival surface who underwent restoration with dry amniotic membrane graft.This study was conducted between Aug 2015 to July 2016 with a mean follow up of 7 weeks. Results: Ten eyes of nine patients were operated which included 4 cases of pterygium, 2 symblepharon with pseudopterygium,1 cojunctivalnevus, 1chemical burn, 1 ocular surface squamous neoplasia and 1malignant melanoma.One eye developed amniotic membrane retraction postoperatvely and in one eye recurrence of growth was seen...........

Keywords: Dry amniotic membrane, Symblepharon, Junctional nevus

[1]. Davis JW. Skin transplantation with a review of 550 cases at the Johns Hopkins Hospital. Johns Hopkins Med J. 1910;15:307.
[2]. Dua HS, Azuara-Blanco A. Amniotic membrane transplantation. Br J Ophthalmol. 1999;83:748–752.
[3]. Meller D, Pauklin M, Thomasen H, Westekemper H, Steuhl K-P. Amniotic membrane transplantation in the human eye. Dtsch
Arztebl Int. 2011;108(14):243–248.
[4]. Rahman I, Said DG, Maharajan VS, Dua HS. Amniotic membrane in ophthalmology: indications and limitations. Eye (Lond).
2009;23(10):1954–1961.
[5]. Prabhasawat P, Barton K, Burkett G, Tseng SC. Comparison of conjunctival autografts, amniotic membrane grafts and primary
closure for pterygium excision. Ophthalmology 1997;104:97485...

Abstract: Background: Himachal Pradesh because of its varied topography is endemic to various medical ailments which are either already present or coincidentally diagnosed in patients presenting for elective or emergency surgical procedures. Aim: The aim of the present study was to determine the incidence and severity of associated medical ailments in Himachal Pradesh population presenting for any surgical intervention and also to evaluate their perioperative course under different anaesthetic techniques. Materials and methods: The present study was prospective........

Keywords-: Diabetes mellitus, Hypertension, Hypothyroidism, Chronic Obstructive Airway Disease, Ischemic Heart Disease, Himachal Pradesh, Surgical patients, Associated medical ailments.

[1]. District Census 2011. Census 2011.co.in.2011. Retrieved 2011-09-30.
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Abstract: Colorectal cancer is a dynamically changing disease entity due to multifactorial reasons. The incidence of cancers is much higher in western countries, suggesting environmental and genetic factors. The frequency has been increasing in our country over last few years, possibly related to changing dietary social habits. In this comprehensive study about colorectal malignancies etiopathogenesis, clinical presentation and various treatment modalities were analysed so that patients must be educated about the symptom and etiology of colorectal malignancy and importance of screening in those with family history, in order to get earlier treatment and better outcome.

Keywords: Colorectal cancer, malignancy, etiopathogenesis

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Abstract: Darier's disease ( keratosis follicularis or Darier- white disease ) is a rare congenital acantholytic , autosomal dominant disease .We report three rare cases of 22-28 year old full term pregnant women with Darier's disease during a observation period of 3 years.Only few such cases have been reported earlier in literature.

[1]. Susan M cooper,susan m burge: darrier disease : American Journal of Clinical Dermatology,February 2003, Volume 4, Issue 2, pp 97–105
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Abstract: To assess the current practices of mothers regarding breastfeeding and weaning of their children up to 2 years of age attending Pediatrics OPD in Gauhati Medical College and Hospital, Guwahati.  To compare the knowledge, attitude and practices of mothers with respect to educational status. Design: Cross sectional study Setting: OPD of a tertiary care hospital. Participants: 536 mothers of children upto 2 years of age. Methods: 536 mothers of children aged upto 2 years........

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Abstract: In CKD patients liver enzymes to be in the lower levels of normal reference range value, while ALP is high due to renal osteodystrophy. As a result the diagnosis and follow up of liver disease in these patients are dilemma and challenging. Aims: The need for new reference ranges of liver enzymes in chronic kidney disease patients for accurate diagnosis and assessment of any liver disease and its progression. Settings and Design: A cross sectional study, which was conducted from January 2014 to January 2015. Methods and Material: Fifty patients in each group were enrolled in the current study according to inclusion criteria and each one was sent for: serum aminotranferases, total serum bilirubin, serum albumin, PT & INR, renal function test and serum electrolyte, virology screen, CBC and abdominal ultrasound. Statistical analysis used: One way ANOVA...........

Keywords: Chronic kidney disease, Hemodialysis, Liver enzymes.

[1]. Hrstic I, Ostojic R. Chronic liver diseases in patients with chronic kidney disease. Acta Med Croatica 2011; 65:349-53.
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Abstract: Background: A valid benchmark for Radiologic equipment failure analysis using a nine mode factor of chronological categories; Improper storage and transportation, Initial failure, Inappropriate handling, Inadequate maintenance, Environmental stress, Production deficiencies, Radom failure, Inappropriate repairs techniques, Wear-out failure. Objectives: To present failure modes that analyze the causes of Radiologic equipment failure based on maintenance history and age of the equipment with preventive and repair maintenance policy Materials and Methods: A triangulational...........

Keywords: Failure mode, Maintenance history, Radiologic equipment, Initial failure

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Abstract: PURPOSE: To report a case of patch graft performed for corneal perforation in a patient with Terrien's marginal degeneration.
METHOD: A young woman presented with sudden painless loss of vision following a trivial trauma to her right eye. On examination, corneal thinning with perforation, lipid deposition and vascularization was noted. Left eye examination also revealed a crescentic thinning with lipid deposition and vascularization. A patch graft was done for the right eye. RESULT: At two months follow-up, graft was clear and her visual acuity was CF2m in right eye with tectonic stable globe.......

Keywords:Terrien's marginal degeneration, patch graft, trivial trauma, perforation

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