iosr-JDMS   Volume-17 ~ Issue-9 ~ September-2018

Abstract: BACKGROUND: All patients who present with clinical features of hepatitis or chronic liver disease or who have elevated serum elevated transaminase levels should be screened for an alcohol use disorder.Typical laboratory findings in ALD include transaminase levels with aspartate aminotransferase greater than alanine aminotransferase as well as increased mean corpuscular volume, gamma-glutamyltranspeptidase, and A:G ratio . AIM: To study the pattern of Hepatic enzymes after abstinence among alcohol dependent patients MATERIALS AND METHODS: : A prospective study on all patients with alcohol dependence attending de addiction centre.A total of 118 patients have been enrolled in the study. Serum biomarkers SGOT {AST} and SGPT (ALT) were analysed at 0,15,30, 60 90 and 180 days RESULTS: Mean age in years of the study population...........

Key words: serum biomarkers AST (SGOT) , ALT (SGPT), Abstinence of alcohol

[1]. Associates of severity of alcohol dependence,Ranjana tiwari, AS Srivatsava,Indian j of Prev. Soc .Med. vol.43,No.1 ,2012
[2]. Analysis of patients admitted with alcohol dependence syndrome in a tertiary care hospital in a calendar year,Nishanth J H, Harish M Tharayil, Praveenlal Kuttichira1 Department of Psychiatry, Government Medical College, Kozhikode, Health Sciences 2014;1(3):JS001A
[3]. Age at onset of alcohol use and alcohol use disorder: Time- trend study in patients seeking De- addiction services in Kerala . Unnikrishnan Raghuraman Nair, K. Vidhukumar, Anil Prabhakaran ; Indian Journal of psychological medicine, jul- aug, 2016,vol 38, issue 4
[4]. Prevalence and pattern of substance use –a study from deaddiction centre,Viney kumar , dharmendar kumar, Delhi journal of psychiatry , vol 16 , no 1, april 2013
[5]. Study of socio demographic and psychosocial aspects of male alcoholics with admission in psychiatry ward ,Deshmukh Deepanjali , Mule Sangita , Faye Abhijeet , Gawande Sushil , Tadke Rahul , Bhave Sudhir , Kirpekar Vivek , PJMS- Volume 4 : Number 2 : July - Dec. 2014..

Abstract: Prognosis of patients with peritonitis due to perforation and its complications was studied using Mannheim peritonitis index score.Patients admitted with diagnosis of secondary peritonitis due to hollow viscous perforation were the study subjects. The total number of study subjects was 30 cases with only 1 mortality which was a case of gastric perforation due to malignancy. As the MPI SCORE rises ,there was increase in morbidity and mortality. MPI scoring system was able to predict morbidity and mortality ,thus serving as a useful tool in the analysis of secondary peritonitis.

Key words: Peritonitis, APACHE -II,Complications,Perforation

[1]. Bohen J,BoulangerM,MeakinsJL,Mclean APH. Prognosis in generalised peritonitis .Relation to cause and risk factors.ArchSurg 1983;118:285-90.
[2]. Tripathi MD,NagarAM,SrivastavaRD,PartapVK:Peritonitis- study of factors contributing to mortality. Indian J Surgery 1933 ,55:342-49 .
[3]. Notash AY ,Salimi J ,RahimianH,Fesharaki MSH ,Abbasi A .Evaluation of Mannheim peritonitis Index and Multiple organ failure score in patients with peritonitis. Indian J .Gastroenterol.2005 ;24(5):197-200.
[4]. Basnet R B,Sharma V K.Evaluation of predictive power of Mannheim Peritonitis Index. PMJN .2010;10(2):27-32.
[5]. Malik AA WaniKA ,Dar LA , Wani MA , Wani RA, Parray FQ .Mannheim Peritonitis Index and APACHE II-Prediction of outcome in patients with peritonitis. Ulus TravmaAcilCerrahiDerg. 2010;16(1):27-32..

Abstract: Background: First reports of fine-needle aspiration cytology (FNAC) as a technique for obtaining diagnostic material date back to the 19th century when, at St Bartholomew's Hospital, London, aspiration was undertaken on a large mass in the liver by the surgeons Stanley and Earle. USG is operator dependent and has a limitation in obese patients and those with large amount of bowel gas. Computed tomography (CT) is a reliable modality and provides good definition of lesions and facilitates visualization of the entire extent of pancreatic pathology. Aims: To study the role of fine needle aspiration cytology in diagnosis of hepatobilliary and pancreatic lesions of patients attending tertiary care hospital and their correlation with ultra sonography. Materials and Methods: 50 patients presented with intra-abdominal lumps attending the outpatient department as well as admitted in Medicine, Surgery and...........

Key words: Liver, Pancreas, Ultrasound, Ultrasonography, Cytology

[1]. Deeley TJ. Needle Biopsy. London: Butter-worths, 1974
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[4]. Griegg EDW, Gray ACH. Note on the lymphatic gland in sleeping sickness. Lancet 1904; 1:1570
[5]. Guthrie CG. Gland puncture as a diagnostic measure. Bull Johns Hopkins Hosp 1921; 32:266-9..

Abstract: Hemifacial microsomia is a congenital deformity with deficiency of skeletal, soft tissue on one side of the face. It is a syndrome including hypoplastic mandibular ramus, ears, defects in facial nerve muscles and temporomandibular joint. The soft tissue malformations are present in the external ear. Underdevelopment of middle ear ossicles can be associated leading on to hearing loss with small external auditory meatus . we present a case of 6-year-old girl, who presented with history of loss of hearing with clinical facial asymmetry and congenital deformity of bilateral external ears.

Key words: Hemifacial microsomia, Hypoplasia, atresia, deformed external ear, facial asymmetry

[1]. Romsee MC, Verdonck A, Schoenaers J, Carels C. Treatment of hemifacial microsomia in a growing child: the importance of co-operation between the orthodontist and the maxillofacial surgeon. J. Orthod. 2004;31:190–200.

[2]. McCarthy JG, Hopper RA, Grayson BH. Craniofacial microsomia. In : Mathes SJ, Hentz VR, editor. Plastic surgery. 2 nd ed. Elsevier Saunders: Philadelphia; 2005. p. 113-34Note that the journal title, volume number and issue number are set in italics.

[3]. Vento AR, LaBrie RA, Mulliken JB. The O.M.E.N.S. classification of hemifacial microsomia. Cleft palate Craniofac J 1991;28:68-77.

[4]. Romsee MC, Verdonck A, Schoenaers J, Carels C. Treatment of hemifacial microsomia in a growing child: the importance of co-operation between the orthodontist and the maxillofacial surgeon. J. Orthod. 2004;31:190–200.

[5]. Heude E, Rivals I, Couly G, Levi G. Masticatory muscle defects in hemifacial microsomia: a new embryological concept. Am J Med Genet A. 2011.

Abstract: Aim: To study pattern of expression of Hormone receptors- ER, PR and HER2 in breast carcinoma and to correlate ER, PR status and HER2/neu expression with traditional prognostic factors. Background: Breast cancer is one of the most common cancers in females. As breast carcinoma is a biologically heterogeneous disease, it is important to assess prognosis for each patient before a therapeutic plan is agreed upon .The use of established biomarkers such as estrogen, progesterone receptors and Her2 over expression play significant role in management of patients. Material Methods: Total 54 histologically.........

Key words: Breast carcinoma, hormone receptors, prognostic factors, predictive markers

[1]. Donegan WL. Tumor-Related Prognostic Factors for Breast Cancer. CA Cancer J Clin. 1997;47:28– 51.
[2]. Cianfrocca M, Fox LJG. Prognostic and predictive factors in early-stage breast cancer.Oncologist. 2004;9:606–16.
[3]. Elston CW, Ellis IO. Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology. 1991;19(5):403–10.
[4]. Walker RA .Immunohistochemical markers as predictive tools for breast cancer. J Clin Pathol.2008;61:689–96.
[5]. Hammond MEH, Hayes DF, Dowsett M, Allred DC, Hagerty KL, Badve S. et al .American Society of Clinical Oncology/College of American

Abstract: Background Cervical cancer is the second most common cancer among women world wide. The estimated burden of cervical cancer in 2012 was approximately 5,28,000 new cases and 2,66,000 deaths with mortality ratio of 52% .Developing countries account for 88% of cases.. In India 1,22,644 new cases occurred of which 50% died of the disease. This study is conducted to assess the risk factors and warning signs of cancer cervix among women in field practice area of Rangaraya Medical College, Kakinada.

Key words: Cervical cancer, risk factors, warning signs, Pap smear

[1]. Madhutandra Sarkar, HiralalKonar, DK Raut. Gynecological malignancies: Epidemiological characteristics of the patients in atertiary care hospital in India.Asian Pacific Journal of cancer Prevention 2012; 13: 2997-3004.
[2]. Hemalatha AL, Gayathri MN, Deepthi B Ramesh, Neelima P Chamarthy, Giripunja M, NayanaNS. Evaluation of trends in the profile of gynecologic malignancies at a tertiary care hospital in Karnataka, South India. Int j Med Res Health Sci. 2013; 2(4)-
[3]. Raja Rao P and Hemanth Kumar B. Study of Socio Demographic Profile of Cancer Cervix patients in Tertiary care Hospital,Karimnagar. Int J Biol Med Res 2012; 3(4):2306-2310.
[4]. Chhabra S, Sonak M, Prem V, Sharma S.Gynaecological malignancies in a rural institute in India. J ObstetGynecol India 2002;58:518-88
[5]. K.Nkyekyer. Pattern of gynecological cancers in Ghana East African Medical Journal October 2000; 77:10.

Abstract: The authors report a case of bilateral lens ectopia in Marfan's disease, in a 16 years old female child, who underwent surgery for the first time at the University Clinics of Lubumbashi, by phacophagy technique associated with a anterior vitrectomy by the pars plana. This observation helps to draw the attention of the community scientist on early surgery in case of bilateral lens ectopia in children to prevent amblyopia.

Key words: lens ectopia, Marfan, phacophagy, vitrectomy

[1]. Charif M. et al. Les manifestations oculaires du syndrome de Marfan. A propos d'un cas.
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[3]. De Paepa A. et al. Revised diagnostic criteria for the Marfen syndrome. American Journal of Medical Genetics, 1996; 62:417-426.
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[5]. Roussat B. et al. Chirurgie de l'ectopie cristallinienne dans la maladie de Marfan chez l'enfant et l'adulte jeune. J.Fr Ophtalmolo, 1995, 18, 3:170-177.

Abstract: I present a case of ectopic pregnancy located within the remnant tube following ipsilateral salpingectomy. This particular pathology is rare and yet has significant consequences for the patient, with mortality rates 10–15 times higher than other ectopic pregnancies. It demonstrates that salpingectomy does not exclude ectopic pregnancy on the ipsilateral side. We suggest careful clinical consideration and bring attention to the current surgical technique.

[1]. S. Boufous, M. Quartararo, M. Mohsin, and J. Parker, ―Trends in the incidence of ectopic pregnancy in New South Wales between 1990–1998,‖ Australian and New Zealand Journal of Obstetrics and Gynaecology, vol. 41, no. 4, pp. 436–438, 2001.

[2]. G. Condous, ―Ectopic pregnancy—risk factors and diagnosis,‖ Australian Family Physician, vol. 35, no. 11, pp. 854–857, 2006. M. Rajkhowa, M. R. Glass, A. J. Rutherford, A. H. Balen, V. Sharma, and H. S. Cuckle, ―Trends in the incidence of ectopic pregnancy in England and Wales from 1966 to 1996,‖ British Journal of Obstetrics and Gynaecology, vol. 107, no. 3, pp. 369–374, 2000

[3]. T. Yano, H. Ishida, and T. Kinoshita, ―Spontaneous ectopic pregnancy occurring in the remnant tube after ipsilateral salpingectomy: a report of 2 cases,‖ Reproductive Medicine and Biology, vol. 8, no. 4, pp. 177–179, 2009. O. Storeide, M. Veholmen, M. Eide, P. Bergsjø, and R...Sandvei, ―The incidence of ectopic pregnancy in Hordaland county, Norway 1976–1993,‖ ActaObstetricia et GynecologicaScandinavica, vol. 76, no. 4, pp. 345–349, 1997. S. Fischer and M. Keirse, ―When salpingectomy is not salpingectomy—ipsilateral recurrence of tubal pregnancy,‖ Obstetrics and Gynaecology International, vol. 2009, Article ID 524864, 3 pages, 2009. S. Lau and T. Tulandi, ―Conservative medical and surgical management of interstitial ectopic pregnancy,‖ Fertility and Sterility, vol. 72, no. 2, pp. 207–215, 1999

Abstract: Background: Agnikarma is an important parasurgical procedure of Ayurvedic surgeons, which has been used widely in the clinical practice. Agnikarma has emerged as an integral part of the Ayurvedic therapeutics. In Ayurveda, agnikarma is a treatment in which heat is applied to a particular part of body to reduce inflammation there and hence the underlying pain. Based on the degree of burn, Agnikarma is classified as Plusthdagdha, Durdagdha, SamyakDagdha and Atidagdha. The agni karma are more superior than kshara as disease treated with agnikarma never happen again...........

Key words: Calcaneal Spur, Agnikarma, Biomechanical, Pronation, Pancha Dhatu Shalaka

[1]. Sharma PV: Cakradatta- (Sanskrit text English translation) Edited and translated edn 2nd. Varanasi: Chowkambha Publishers; 1998 [2]. Gupta P: Agnikarma Technological Innovations (Treatment by Therapeutic Burning) edn 1st. Nagpur: Prabha publications; 1992
[3]. Ramkaran S, Vaidya Bhagwan D: Agnivesha's Charaka Samhita. Text with English translation. Translated , vol 1. Varanasi: Chowkambha Publishers; 2005

[4]. A Clinical Study of Efficacy of Agnikarm: An Ancient Treatment Method in the Management of Heel Pain. Aaccessed Apr 27 2018..

Abstract: Maxillary first molar with two palatal canals is a rare finding as mostly extra canals are found in the mesial canal as MB2. Clinicians should have a good knowledge on the anatomy of root canal system and be alert about the possible existence of any variation in the canal morphology. Careful examination of the radiograph along with careful detection of the pulp chamber will go a long way in the success of endodontic treatment.

Key words: Maxillary first molar, canal, root canal, radiograph, pulp chamber

[1]. SilkeHolderrieth, Christian Ralf Gernhardt. Maxillary Molars with Morphologic Variations of the Palatal Root Canals: A Report of Four Cases.JEndod. 2009 Jul;35(7):1060-5.

[2]. Cleghorn BM, Christie WH, Dong CC. Root and root canal morphology of the human permanent maxillary first molar: a literature review.JEndod. 2006 Sep;32(9):813-21

[3]. Ingle JI, Bakland L, J. Craig Baumgartner. Endodontics 6th ed.2008, 174-77p.
[4]. Frank J. Vertucci, Gainesville, Fla. Root canal anatomy of the human permanent teeth. Oral surgery,OralMedicine,Oral Pathology. 1984;58:589-99.

[5]. Maggiore F, Jou YT, Kim S. A six-canal maxillary first molar: case report. IntEndod J 2002;35:486–91...

Abstract: Since the original description of porokeratosis in 1893 by Mibelli, various other forms of this disease have been described. Among these variants zosteriform porokeratosis is considered to be extremely rare with higher rate of malignant transformation. We are reporting an unusual presentation of zosteriform porokeratosis resembling nevoid psoriasis in a 19 year old boy over the left side of abdomen associated with intense pruritus.

Key words: zosteriform porokeratosis, nevoid psoriasis, pruritus

[1] Bolognia JL, Jorizzo JL, Rapini RP. Dermatology. 2008; 2:1708–09.
[2] Schamroth JM, Zlotogorski A, Gilead L. Porokeratosis of Mibelli. Overview and review of the literature. Acta Derm Venereol 1997; 77:207-213.
[3] Schamroth JM, Zlotogorski A, Gilead L. Porokeratosis of Mibelli. Overview and review of literature. Acta Derma Venereol 1997;77:207-213.
[4] Otsuka F, Iwata m, Watanabe R, Chi Hi, Ishibashi Y. Porokeratosis: clinical and cellular characterization of its cancer- prone nature.J Dermatol 192;19:702-706.

[5] Singh G, Nigam PK, Kumar M, Linear porokeratosis. Indian J Dermatol Venerol Leprol. 1987; 53:41-42...

Abstract: Le léiomyosarcome du col utérin (LMS) représente une entité histologique particulièrement rare et agressive. Nous rapportant les observations de cinq patientes traitées à l'institut national tunisien de cancérologie Salah Azaïez entre 1998 et 2014 pour un LMS du col confirmé histologiquement dont deux cas survenant après une hystérectomie subtotale pour des pathologies bénignes. L'âge moyen de nos patientes était de 48.6 ans. Une patiente était classée au stade IV de FIGO 2009, trois patientes étaient au stade Ib2 et une autre patiente était au stade IIb. Nous avions réalisé une colpo-hystérectomie totale avec lymphadénectomie pelvienne bilatérale (CHL) chez trois patientes, une cervicectomie associée...........

[1]. Bansal S, Lewin SN, Burke WM, Deutsch I, Sun X, Herzog TJ, et al. Sarcoma of the cervix: natural history and outcomes. Gynecol Oncol. 2010;118(2):134–138.
[2]. Cymek S, Zyliński A, Soszka T. Cervical leiomyosarcoma after uterine surpravaginal amputation. Ginekol Pol. 2002;73(7):613–616.
[3]. Sturdy DE. Leiomyosarcoma of cervical stump following subtotal hysterectomy. Br J Surg. 1959;46(198):369–370.
[4]. Fadare O, Ghofrani M, Stamatakos MD, Tavassoli FA. Mesenchymal lesions of the uterine cervix. AJSP Rev Rep. 2006;11(3):140–152.
[5]. Irvin W, Presley A, Andersen W, Taylor P, Rice L. Leiomyosarcoma of the cervix. Gynecol Oncol. déc 2003;91(3):636‑42...

Abstract: Various bio-compatible materials can be used to restore the function and esthetics of any congenital or acquired defects. Proper assessment, examination, planning and rehabilitation of the distorted body parts has been the target of clinical maxillofacial prosthodontics. The aim of this article is to present a case report of fabrication of silicone prosthesis for a patient with a congenital bilateral auricular defect.

[1]. PS Kumar, RC Savadi. Bilateral implant - retained auricular prosthesis for a patient with congenitally missing ears. A clinical report. J Prosthodont. 2012;21:322–27. [PubMed]

[2]. JC Lemon, MS Chambers, PJ Wesley, JW Martin.Technique for fabricating a mirror image prosthetic ear. J Prosthet Dent. 1996;75:292–93. [PubMed]

[3]. LM Sykes, AM Parrot, P Owen. Applications of rapid prototyping technology in maxillofacial prosthetics. Int J Prosthodont. 2004;17:454–89. [PubMed]

[4]. Singh Ajay, G Shounak, Sumankar, Ahmed Imran. Silicone prosthesis for a patient with unilateral ear defect: a clinical case report. Eur J Gen Dent. 2013;2:315–19.

[5]. HG EL Charkawi, AG EL Sharkawi. A simplified technique for orientation of a bone anchored auricular prosthesis: a clinical report. J Oral Maxillofac Res. 2012;3:1–7. [PMC free article] [PubMed]..

Abstract: Constitutional thrombophilia is a rare disease, with rather complex mechanisms. Several factors are incriminated, including environmental factors but especially genetic factors sometimes involving several anomalies. Faced with the occurrence of thrombotic manifestations at a young age or with a family history of these, the constitutional origin of thrombophilia is strongly suspected and requires the search for the causal genetic anomaly. Through our two observations and a literature review of this pathology, we recall the physiopathological mechanisms, while highlighting the different etiologies of constitutional thrombophilia.

Key words: constitutional thrombophilia, pathophysiology, etiology

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[5]. Michot C,GarnierA,DaugerS.Thrombose néonatale des veines rénales : l'expérience récente de l'hôpital Robert-Debré. ArchPediatr2011;18:1055–61...