iosr-JDMS   Volume-17 ~ Issue-9 ~ September-2018

Abstract: Non motor symptoms(NMS) in Parkinson's Disease constitute a major clinical challenge, as they are common,yet often overshadowed by the dominance of motor symptoms and high unawareness of these among treating health care professionals. These NMS significantly affect the quality of life and may precipitate hospitalization. Although common the NMS of PD are not well recognised in clinical practice. The aim of our study was to find the prevalence of nonmotor features across the various stages of Idiopathic Parkinson's Disease and 2) to correlate it with the severity and duration of the disease..

Key words: NMS,NMS Quest, NMSS,UPDRS,Hoehn and Yahr Staging

[1]. Jankovic J (April 2008). Parkinson's disease: clinical features and diagnosis. Journal of Neurology,Neurosurgery and Psychiatry. 79 (4): 368–76.
[2]. Aarsland D, Brønnick K, Ehrt U,et al. (January 2007). Neuropsychiatric symptoms in patients with Parkinson's disease and dementia: frequency, profile and associated care giver stress.Journal of Neurology,Neurosurgery and Psychiatry. 78 (1): 36–42.
[3]. Caballol N, Martí MJ, Tolosa E (September 2007). Cognitive dysfunction and dementia in Parkinson disease.Movement Disorders. 22 Suppl 17: S358–66.
[4]. Pfeiffer RF (February 2003). Gastrointestinal dysfunction in Parkinson's disease.Lancet Neurology. 2 (2): 107–16.
[5]. Davie CA (2008). A review of Parkinson's disease.Br Med Bull. 86: 109–27...

Abstract: Fear connected to anaesthesia has lead to majority of patients from being tentative to undergo routine as well as life saving surgical procedures. Fear and anxiety coupled with the thought of surgical events causes many endocrine as well as hemodynamic instabilities. To evaluate this we formed a question bank which was provided to 400 patients during pre anaesthetic checkups , which included patient demographics, their fears pertaining anaesthesia and previous exposure to anaesthesia. Eighty four percent were subjected to preoperative fear , with pain during surgical procedure being most common at 80%, followed by intra operative awareness (71%) and needle pricks (66%). There are very noteworthy predictors as females experienced more fear and so did those above age of 45 years. We suggest adequate counselling and management of the patients pharmacologically earlier to the procedure as effective steps in gaining trust and relieving anxiety in patient.

Key words: Anaesthesia, Fear, Anxiety, Cross-sectional study

[1]. Kain ZN, Wang SM, Mayes LC, Caramico LA, Hofstadter MB. Distress during the induction of anesthesia and postoperative behavioral outcomes. Anesth Analg. 1999;88:1042–7.

[2]. Mavridou P, Dimitriou V, Manataki A, Arnaoutoglou E, Papadopoulos G. Patient's anxiety and fear of anesthesia: Effect of gender, age, education, and previous experience of anesthesia. A survey of 400 patients. J Anesth. 2013;27:104–8.

[3]. Tolksdorf W, Berlin J, Rey ER, Schmidt R, Kollmeier W, Storz W, et al. Preoperative stress. Study of the mental behavior and parameters of physiological stress in non-premedicated patients during the preoperative period. Anaesthesist. 1984;33:212–7

[4]. Johnson N, Crompton AC. Who finds cervical laser therapy painful? Gynecol Oncol. 1994;52:44–9.

[5]. Mendl G. The effect of the preanesthetic interview on anxiety prior to minor interventions. Cah Anesthesiol. 1990;38:237–9.

Abstract: A fifty-two years old female referred to the oral medicine clinic, Faculty of Dentistry, University of the Western Cape complaining ofmouthburning that has been present for more than two years.The patient mentioned that she had been diagnosed with cutaneous lichen planus in 2010. She felt improvement of her skin condition since the diagnosis and discontinued follow up with no treatment. Her medical history revealed that she was hypertensive and on Pharmapress 10 mg and Radix 12.5 mg daily. She also reported a history of allergy to penicillin and sulphonomide. Extra-oral examination showed round brown- black pigmented macules and papules that were located in the lower back. There were neither lesions located on the flexor surfaces of the extremities nor associated itching with her back lesions (Fig.1)........

[1]. Ismail S, Kumar S, Zain R. Oral lichen planus and lichenoid reactions :ethiopathogenesis, diagnosis, management and malignant transformation. J Oral Sci [Internet]. 2007;49(2):89–106. Available from: http://www.ncbi.nlm.nih.gov/pubmed/17634721
[2]. Roopashree MR, Gondhalekar R V., Shashikanth MC, George J, Thippeswamy SH, Shukla A. Pathogenesis of oral lichen planus - a review. Vol. 39, Journal of Oral Pathology and Medicine. 2010. p. 729–34.
[3]. Au J, Patel D, Campbell JH. Oral Lichen Planus. Vol. 25, Oral and Maxillofacial Surgery Clinics of North America. 2013. p. 93–100.
[4]. Jayachandran S, KoijamSashikumar S. Management of oral lichen planus. Jimsa. 2012;25(3):205–8.
[5]. Lester D., Thompson M. Oral lichen planus. Oral lichen Planus. 2012;87(4):233–9...

Abstract: With the advent of adhesive and digital dentistry along with the introduction of new generations of ceramic materials, endocrowns have become more spread to restore endodontically treated teeth.1 Endocrowns are adhesively placed restorations with total cuspal coverage.2 The clinical impact of bleaching agents over the color stability of ceramics and composite CAD/CAM materials is of major concern regarding the shade and esthetics of the restoration.3 Hydrogen Peroxide (HP) and Carbamide Peroxide (CP), the 2 most popular bleaching products, can change the physical properties of dental restorations such as color, surface roughness, hardness and ion leakage 3. Our study aims to evaluate the effect of two bleaching protocols on the color stability and surface roughness of endocrowns made with two CAD/CAM materials; Ceramill Composite (CC) (Amman Girrbach, Germany) and........

[1]. Erika Lander, D. & /Didier Dietschi. Endocrowns: A clinical report QUINTESSENCE. 28, 877–884 (1993).
[2]. El-Damanhoury, H. M., Haj-Ali, R. N., Platt, J. A. & Hatem El-Damanhoury, R. H.-A. Fracture Resistance and Microleakage of Endocrowns Utilizing Three CAD-CAM Blocks. Oper. Dent. j 40, 201–210 (2015).
[3]. El-Murr, J., Ruel, D. & St-Georges, A. J. Effects of external bleaching on restorative materials: a review. J. Can. Dent. Assoc. 77, b59 (2011).
[4]. Ruse, N. D. & Sadoun, M. J. Resin-composite Blocks for Dental CAD/CAM Applications. J. Dent. Res. 93, 1232–1234 (2014).
[5]. Nguyen, J. F., Migonney, V., Ruse, N. D. & Sadoun, M. Properties of experimental urethane dimethacrylate-based dental resin composite blocks obtained via thermo-polymerization under high pressure. Dent. Mater. 29, 535–541 (2013).

Abstract: Aims and objectives: 1 To evaluate the antidiabetic effect of polyherbal extract in comparison with Gliclazide 2 To evaluate the effect of polyherbal extract on serum creartinine, CRP levels and WBC counts in comparison with standard drug Gliclazide in alloxan induced diabetic Rats Materials and method: Rats were randomly divided into 5 groups, each comprising 6 rats. Group 1 - Normal control distilled water, Group 2 – standard drug gliclazide 25mg/kg, Group 3 – Polyherbal extract (T1)– 300mg/kg, group 4 – Polyherbal..........

Key words: Diabetes, Creatinine, CRP, HbA1c, polyherbal extract, Gliclazide

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[3]. Nam Han Cho. International Diabetes Federation. Diabetes Atlas, 2013, 6th edition, page no 10-13
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Abstract: Congenital high airway obstruction syndrome (CHAOS) is the obstruction of the fetal upper airways, which may be partial or complete. It is usually incompatible with life. Prenatal recognition of the disease is quite important due to the recently described management options. Bilateral renal agenesis is also an uncommon prenatal diagnosis. It is a lethal anomaly with 50% of the fetuses being stillborn; therest would die shortly after birth. It is also associated with many other congenital anomalies many of which have autosomaldominant or recessive inheritance. Absence of kidneys in renal fossae with pulmonary hypoplasia and oligohydramnios or anhydramnios strongly suggests the diagnosis of bilateral renal agenesis..

Key words: hyperechoic lungs, oligohydramnios, congenital anomalies, fetus, Sonography

[1]. J. L. Roybal, K. W. Liechty, H. L. Hedrick et al., "Predicting the severity of congenital high airway obstruction syndrome," Journal of Pediatric Surgery, vol. 45, no. 8, pp. 1633–1639, 2010.

[2]. P. Joshi, L. Satija, R. A. George et al., "Congenital high airway obstruction syndrome-antenatal diagnosis of a rare case of airway obstruction using multimodality imaging," Medical Journal Armed Forces India, vol. 68, no. 1, pp. 78–80, 2012.

[3]. M. Garg, "Case report: antenatal diagnosis of congenital high airway obstruction syndrome. Laryngeal atresia," Indian Journal of Radiology and Imaging, vol. 18, no. 4, pp. 350–351, 2008.

[4]. J. Courtier, L. Poder, Z. J. Wang, A. C. Westphalen, B. M. Yeh, and F. V. Coakley, "Fetal tracheolaryngeal airway obstruction: prenatal evaluation by sonography and MRI," Pediatric Radiology, vol. 40, no. 11, pp. 1800–1805, 2010.

[5]. F. V. Coakley, H. Hricak, R. A. Filly, A. J. Barkovich, and M. R. Harrison, "Complex fetal disorders: effect of MR imaging on management: preliminary clinical experience," Radiology, vol. 213, no. 3, pp. 691–696, 1999.

Abstract: Dysfunctional uterine bleeding is one of the important causes of menstruation abnormality in perimenopausal age group and the causes are to be evaluated by studying the endometrial biopsy meticulously. Among different causes of dysfunctional uterine bleeding, endometrial hyperplasia and endometrial carcinoma are lethal to the patients. Aims: The purpose of this research is to find out the incidence of endometrial hyperplasia and endometrial carcinoma as causative agents of dysfunctional uterine bleeding in this age group (45-55yrs) early, so that the treatment can be started as early as possible. Settings & Design: It is a descriptive study. Materials and Methods: Over........

Key words: Carcinoma; Endometrium; Hyperplasia; Perimenopausal

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[4]. Dangal G: A study of endometrium in patients with abnormal uterine bleeding at Chitwan valley. Kathmandu University Medical Journal, 2003;1(2):110-112.
[5]. Muzaffar M, Akhtar KA, Yasmeen S, Rehman MU, Iqbal W, Khan MA: Menstrual irregularities with excessive blood loss: a clinic-pathological correlation. The Journal of Pakistan Medical Association, 2005;55(11):486-489.